CN203164163U - Medical breath testing device - Google Patents
Medical breath testing device Download PDFInfo
- Publication number
- CN203164163U CN203164163U CN 201320129968 CN201320129968U CN203164163U CN 203164163 U CN203164163 U CN 203164163U CN 201320129968 CN201320129968 CN 201320129968 CN 201320129968 U CN201320129968 U CN 201320129968U CN 203164163 U CN203164163 U CN 203164163U
- Authority
- CN
- China
- Prior art keywords
- acoustic wave
- surface acoustic
- adsorption tube
- chromatographic column
- detecting device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Abstract
The utility model discloses a medical breath testing device which is low in testing cost, simple in process, short in duration, accurate in result and extensive in application. The medical breath testing device comprises a sample feed opening, a sampling pump, a six-way valve, a gas carrying bottle, an adsorption tube, a chromatographic column, a surface acoustic wave detector and a data processing system, wherein the six-way valve is respectively connected with the sample feed opening, the gas carrying bottle, the first end of the adsorption tube, the second end of the adsorption tube, the sampling pump and one end of the chromatographic column, the other end of the chromatographic column is connected with the surface acoustic wave detector, and the output end of the surface acoustic wave detector is connected with the data processing system.
Description
Technical field
The utility model belongs to technical field of medical, relates in particular to a kind of medical breath detection device.
Background technology
The uncommon ripple of ancient Greek undercuts the epoch, and doctors come the auxiliary diagnosis disease with regard to knowing the smell by detecting patient exhales.In the France in 18th century, the pioneer of Antoine Lavoisier-modern chemical analysis, he is that first analyzes expiration, proves that it contains carbon dioxide.Modern breath tester starts from 1971, and Nobel chemistry Prize winner Linus ripple woods finds that the human normal concentration that comprises many different volatile organic compounds of exhaling is very low.But, these technology are just used by indivedual experts at present, also be not widely applied in the medical practice, this is because the organism kinds in detect exhaling and the variation of quantity can only manually be finished by experienced expert, so just makes that this expiration testing cost is high, process is complicated, the time is very long, out of true as a result.
Summary of the invention
The technical problems to be solved in the utility model provides that a kind of testing cost is lower, process is simple, the time is short, the result is accurate, widely used medical breath detection device.
The technical scheme that addresses the above problem is: this medical breath detection device, it comprises injection port, sampling pump, six-way valve, carrier gas bottle, adsorption tube, chromatographic column, surface acoustic wave detecting device, data handling system, six-way valve connects second end, the sampling pump of first end, the adsorption tube of injection port, carrier gas bottle, adsorption tube, an end of chromatographic column respectively, the other end of chromatographic column connects the surface acoustic wave detecting device, and the output terminal of surface acoustic wave detecting device inserts data handling system.
During sampling, injection port connects first end of adsorption tube, adopts pump to connect second end of adsorption tube, and carrier gas bottle connects chromatographic column, and the expiration sample is inhaled into injection port by sampling pump, enters adsorption tube and is adsorbed at this via six-way valve; Injection port connects sampling pump during analysis, carrier gas bottle connects first end of adsorption tube, second end of adsorption tube connects chromatographic column, adsorption tube heating, sample desorption, brought into chromatographic column by the carrier gas in the carrier gas bottle and separate, separating the different material in back can flow out from chromatographic column successively, arrives the surface acoustic wave detecting device then, and the surface acoustic wave detecting device detects frequency change, record these variations, after data-switching, obtain chromatogram; Utilize data handling system that chromatogram is handled and obtain comparing result; Testing cost is lower like this, process is simple, the time is short, the result is accurate, be widely used.
Description of drawings
Structural representation when Fig. 1 is preferred embodiment sampling of medical breath detection device of the present utility model;
Fig. 2 is the structural representation of preferred embodiment of medical breath detection device of the present utility model when analyzing.
Embodiment
We know now, and sample normal person's expiration comprises usually and surpasses 200 different volatile organic compounds, and wherein great majority are in picomole (Pico molar) concentration.The kind of these compounds and content, metabolic closely bound up with in the body.When (pathology) when unusual, the variation that will produce new compound or existing compound generating capacity in the body appear in part organ in the body.Detect these organism kinds in exhaling and the variation of amount, according to the way of artificial neural network isotype identification, we can make diagnosis to disease (for example in lung cancer, pulmonary tuberculosis, breast cancer, the organ transplant body rejection etc.).
Be example with lung cancer.
Lung cancer is one of modal malignant tumour in the world at present, accounts for 16% of whole malignant tumours, 28% of malignant tumour death.At present, only 14.1%, 60% patient is dead in back 1 year of diagnosis for 5 years survival rates of patient diagnosed.Means such as the triage techniques of tradition lung cancer such as X line, phlegm inspection, Bronchofiberscope can not reduce screened crowd's lung cancer mortality.Testing process is comparatively loaded down with trivial details, and the time is longer, dynamic monitoring in early days and being restricted.Advanced technologies such as new technology such as spiral CT, positron emission imaging, molecule damage check technology be applied to the lung cancer early diagnosis and by stages, dynamic monitoring state of an illness aspect obtains certain progress.But because of its expense costliness, methodology complexity, the technical requirement height is difficult at present as conventional lung cancer early diagnosis and dynamic monitoring means.
Shown in Fig. 1-2, applicant's this medical breath detection device, it comprises injection port 1, sampling pump 5, six-way valve 2, carrier gas bottle 3, adsorption tube 4, chromatographic column 6, surface acoustic wave detecting device 7, data handling system 8, six-way valve connects second end, the sampling pump of first end, the adsorption tube of injection port, carrier gas bottle, adsorption tube, an end of chromatographic column respectively, the other end of chromatographic column connects the surface acoustic wave detecting device, and the output terminal of surface acoustic wave detecting device inserts data handling system.
During sampling, injection port connects first end of adsorption tube, adopts pump to connect second end of adsorption tube, and carrier gas bottle connects chromatographic column, and the expiration sample is inhaled into injection port by sampling pump, enters adsorption tube and is adsorbed at this via six-way valve; Injection port connects sampling pump during analysis, carrier gas bottle connects first end of adsorption tube, second end of adsorption tube connects chromatographic column, adsorption tube heating, sample desorption, brought into chromatographic column by the carrier gas in the carrier gas bottle and separate, separating the different material in back can flow out from chromatographic column successively, arrives the surface acoustic wave detecting device then, and the surface acoustic wave detecting device detects frequency change, record these variations, after data-switching, obtain chromatogram; Utilize data handling system that chromatogram is handled and obtain comparing result; Testing cost is lower like this, process is simple, the time is short, the result is accurate, be widely used.
Preferably, described carrier gas bottle 3 is inert gas carrier gas bottles, for example helium tank, nitrogen cylinder, argon bottle etc.
Preferably, described surface acoustic wave detecting device 7 comprises mode of resonance surface acoustic wave component, piezoelectric crystal plate, semiconductor temperature assembly.
Preferably, described data handling system 8 is computing machines.
Preferably, this pick-up unit also comprises attemperating unit (not shown among Fig. 1-2), and attemperating unit connects injection port, six-way valve, adsorption tube, chromatographic column, surface acoustic wave detecting device respectively, in order to control the temperature of these parts respectively.
The above; it only is preferred embodiment of the present utility model; be not that the utility model is done any pro forma restriction; any simple modification, equivalent variations and modification that every foundation technical spirit of the present utility model is done above embodiment all still belong to the protection domain of technical solutions of the utility model.
Claims (5)
1. medical breath detection device, it is characterized in that: it comprises injection port (1), sampling pump (5), six-way valve (2), carrier gas bottle (3), adsorption tube (4), chromatographic column (6), surface acoustic wave detecting device (7), data handling system (8), six-way valve (2) connects injection port (1) respectively, carrier gas bottle (3), first end of adsorption tube (4), second end of adsorption tube (4), sampling pump (5), one end of chromatographic column (6), the other end of chromatographic column (6) connects surface acoustic wave detecting device (7), and the output terminal of surface acoustic wave detecting device inserts data handling system (8).
2. medical breath detection device according to claim 1, it is characterized in that: described carrier gas bottle (3) is the inert gas carrier gas bottle.
3. medical breath detection device according to claim 1 and 2, it is characterized in that: described surface acoustic wave detecting device (7) comprises mode of resonance surface acoustic wave component, piezoelectric crystal plate, semiconductor temperature assembly.
4. medical breath detection device according to claim 3, it is characterized in that: described data handling system (8) is computing machine.
5. medical breath detection device according to claim 1, it is characterized in that: this pick-up unit also comprises attemperating unit, attemperating unit connects injection port, six-way valve, adsorption tube, chromatographic column, surface acoustic wave detecting device respectively, in order to control the temperature of these parts respectively.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 201320129968 CN203164163U (en) | 2013-03-21 | 2013-03-21 | Medical breath testing device |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 201320129968 CN203164163U (en) | 2013-03-21 | 2013-03-21 | Medical breath testing device |
Publications (1)
Publication Number | Publication Date |
---|---|
CN203164163U true CN203164163U (en) | 2013-08-28 |
Family
ID=49025340
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 201320129968 Expired - Fee Related CN203164163U (en) | 2013-03-21 | 2013-03-21 | Medical breath testing device |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN203164163U (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103163268A (en) * | 2013-03-21 | 2013-06-19 | 北京华新安科科技有限公司 | Medical breath testing device and testing method thereof |
CN107041751A (en) * | 2017-04-01 | 2017-08-15 | 浙江大学 | A kind of surface acoustic wave sensor of breathing state detecting system and wireless and passive |
-
2013
- 2013-03-21 CN CN 201320129968 patent/CN203164163U/en not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103163268A (en) * | 2013-03-21 | 2013-06-19 | 北京华新安科科技有限公司 | Medical breath testing device and testing method thereof |
CN107041751A (en) * | 2017-04-01 | 2017-08-15 | 浙江大学 | A kind of surface acoustic wave sensor of breathing state detecting system and wireless and passive |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Wang et al. | Investigation and identification of potential biomarkers in human saliva for the early diagnosis of oral squamous cell carcinoma | |
CN103163268A (en) | Medical breath testing device and testing method thereof | |
Zhang et al. | Noninvasive strategy based on real-time in vivo cataluminescence monitoring for clinical breath analysis | |
CN108956792A (en) | The high performance liquid chromatography detection of free serum mannose and glucose | |
CN102495146B (en) | Compound fingerprint atlas model used in early-stage gastric cancer diagnosis/early warning, and establishing method thereof | |
US11692978B2 (en) | VOC markers in saliva for diagnosis of gastric cancer and gastric cancer diagnostic method using same | |
CN112305121B (en) | Application of metabolic marker in atherosclerotic cerebral infarction | |
CN203164163U (en) | Medical breath testing device | |
CN107462647A (en) | Pheochromocytoma diagnostic kit and its application method | |
Marder et al. | A multiple‐method comparative study using GC–MS, AMDIS and in‐house‐built software for the detection and identification of “unknown” volatile organic compounds in breath | |
CN112986441A (en) | Tumor marker screened from tissue metabolism contour, application thereof and auxiliary diagnosis method | |
CN101246176B (en) | Mass spectrum kit for detecting squamous-cell carcinoma antigen feminine cervical carcinoma serum protein and preparation method thereof | |
CN110763776B (en) | LC-HG-AFS detection method of thioarsenate | |
CN102182116B (en) | Preparation and application method of filter paper collecting biological sample | |
CN101839890B (en) | Method for detecting serum polypeptide for kidney transplantation rejection | |
CN105067390A (en) | Method for measuring ammonia content in mainstream smoke of cigarettes | |
CN102324001A (en) | Method for predicting gastric cancer on the basis of high performance liquid chromatography/mass spectrometry (HPLC/MS) metabonomics data analysis | |
CN107022018B (en) | Detect the composition and product and purposes of insulin resistance | |
CN112285232B (en) | Application of Ulexin C detection reagent in preparation of COPD (chronic obstructive pulmonary disease) diagnostic kit | |
CN101961472A (en) | Detection method for lung-soothing syrup | |
CN104614462B (en) | A kind of plateau pneumochysis diagnosis marker and application thereof and diagnostic kit | |
Yang et al. | Isolation of leukemia and breast cancer cells from liquid biopsies and clinical samples at low concentration in a 3D printed cell separation device via transferrin-receptor affinity | |
CN211576692U (en) | Sampling device with nitrogen-filled protective layer | |
CN103822993B (en) | Method for detecting content of herba lagotis in preparation | |
Åkesson et al. | Operator dependent variability in quantitative analysis of myocardial perfusion images |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130828 Termination date: 20140321 |