CN203132975U - Biological tissue clamp for testing adhesive power of biological tissue adhesion material - Google Patents

Biological tissue clamp for testing adhesive power of biological tissue adhesion material Download PDF

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Publication number
CN203132975U
CN203132975U CN 201320071949 CN201320071949U CN203132975U CN 203132975 U CN203132975 U CN 203132975U CN 201320071949 CN201320071949 CN 201320071949 CN 201320071949 U CN201320071949 U CN 201320071949U CN 203132975 U CN203132975 U CN 203132975U
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CN
China
Prior art keywords
biological tissue
adhesion
adhesion material
anchor clamps
plate
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Expired - Lifetime
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CN 201320071949
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Chinese (zh)
Inventor
纪晓寰
周颖
吴国华
邓峰
韩晴晴
孙宾
朱美芳
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Donghua University
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Donghua University
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Priority to CN 201320071949 priority Critical patent/CN203132975U/en
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Publication of CN203132975U publication Critical patent/CN203132975U/en
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Abstract

The utility model belongs to the field of mechanical testing instruments, and in particular relates to a biological tissue clamp for testing adhesive power of a biological tissue adhesion material. The biological tissue clamp for testing the adhesive power of the biological tissue adhesion material comprises an upper clamp plate and a lower clamp plate, wherein the upper clamp plate comprises an upper fixing plate fixedly connected with the lower fixing plate, and a bearing table which is protruded in the upper fixing plate; and the lower clamp plate comprises a lower fixing plate fixedly connected with the upper fixing plate and a through hole matched with the bearing table in the lower fixing plate. According to the technical scheme provided by the utility model, various biological tissue slices are effectively fixed for a long time, the surface flatness of the biological tissues is guaranteed. Because the size and the shape of the bearing table are immobile, the contact area of the biological tissues and adhesion material samples is immobile every time, so that faults during experiment measurement are reduced, and the clamping process of the biological tissues is easy, the clamping is convenient to operate, and the experiment efficiency is greatly improved.

Description

Be used for test organisms and organize biological tissue's anchor clamps of adhesion material adhesion
Technical field
The utility model belongs to the mechanical testing instrument field, is specifically related to a kind of biological tissue's anchor clamps of organizing the adhesion material adhesion for test organisms.
Background technology
Biological tissue's adhesion material mainly is the macromolecular material for biologic adhesion preparation and sealer field.Wherein biologic adhesion preparation has the characteristic of certain affinity to biological mucosa by some macromolecular material, with these polymer substances as pharmaceutical carrier, make preparation have the preparation technique of location, sustained release performance, and biological sealer refers to that biodegradable film class or glue family macromolecule material adhesion are to the wound of tissue, avoid wound to be subjected to outside the infection, prevent effectively organize blood oozing from the wound surface and veinlet hemorrhage, seal defective tissue, promote wound healing, prevent tissue adhesion.Therefore biological tissue's adhesion material most important with the testing in vitro biological tissue adhesion in above-mentioned field.
Be used at present the metering mechanism that test organisms is organized the device of adhesion material adhesion mainly to comprise the pedestal of biological tissue's anchor clamps, the adhesion material sample plummer relative with biological tissue anchor clamps, secure attachment material sample plummer and applied variable force to biological tissue's anchor clamps, the power that pedestal and metering mechanism apply is opposite, increase the power that applies along with metering mechanism, make the biological tissue section and the adhesion material sample separation that adhere to each other, during by separation, the power that metering mechanism applies can calculate the size of adhesion.
But biological tissue section is to be attached to fully on the anchor clamps by seccotine at present, makes that biological tissue is difficult for fixing because tissue contains tissue fluid, causes the failure of an experiment.And because artificial sample preparation can't guarantee that the shape and size of biological tissue section are unified, will cause the poor repeatability of experimental data like this, the comparison difficulty.
The utility model content
Technical problem to be solved in the utility model is the fixedly geomery disunities of shakiness and biological tissue section of existing biological tissue anchor clamps, cause test data inaccurate, in order to overcome above deficiency, a kind of biological tissue's anchor clamps of organizing the adhesion material adhesion for test organisms are provided.
In order to solve the problems of the technologies described above, the technical solution of the utility model is: describedly organize biological tissue's anchor clamps of adhesion material adhesion to comprise train wheel bridge and lower plate for test organisms, described train wheel bridge comprises the upper mounted plate of fixedlying connected with lower plate and the plummer of upper mounted plate protrusions, described lower plate comprise with the fixedly connected bottom plate of upper mounted plate and bottom plate in the through hole that matches with plummer.The center section of biological tissue section overlays on the plummer, plummer passes through hole, the marginal portion of biological tissue section is clamped in fixedly connected upper mounted plate and bottom plate between train wheel bridge and the lower plate, biological tissue section is fixed between train wheel bridge and the lower plate, is overlying on the size and dimension of biological tissue section of carrier-table surface by relative fixed.
Further, described upper mounted plate is fixedlyed connected by fixture with bottom plate, and described fixture is magnet or threaded connector.
Further, described upper mounted plate is provided with fixed orifice, and described bottom plate is provided with and last fixed orifice lower fixed hole one to one, and last fixed orifice and lower fixed hole are used for arranging fixture.
Further, describedly organize biological tissue's anchor clamps of adhesion material adhesion to comprise a lower plate that above clear size of opening is different for test organisms.Cross the unitarity that pine or tension can not influence final detection result because be fixed between train wheel bridge and lower plate biological tissue section, so the different-thickness biological tissue section needs the lower plate of different clear size of opening to cooperate with plummer.
Further, describedly organize the material of biological tissue's anchor clamps of adhesion material adhesion to be selected from lightweight stainless steel, vitallium, titanium alloy, polypropylene or tygon for test organisms, above-mentioned material density is less to be suitable for making this small and exquisite testing tool, and often contact with biological fluid in the test, above-mentioned material is corrosion-resistant, easy to clean, is difficult for contaminated.
Can carry out series of tests at the different biological tissue's anchor clamps of many group plummer sizes during test, for reducing test error.
The technical scheme that the utility model provides can be effective, permanent fixing various biological tissue sections, guarantee the surfacing of biological tissue.Because the size and dimension of plummer is fixed, so the contact area of each biological tissue and adhesion material sample is fixed, and reduced the error in the experiment measuring process, and the process of biological tissue clamped is simple, be convenient to operation, improved conventional efficient greatly.
Description of drawings
Fig. 1 is the separation synoptic diagram of biological tissue described in the utility model anchor clamps;
Fig. 2 is the wiring layout of biological tissue described in the utility model anchor clamps.
Shown in the figure:
The 1-train wheel bridge, 11-upper mounted plate, 12-plummer, the last fixed orifice of 13-;
The 2-lower plate, 21-bottom plate, 22-through hole, 23-lower fixed hole.
Embodiment
Below in conjunction with accompanying drawing the utility model is described in detail:
As illustrated in fig. 1 and 2, described in the utility modelly organize biological tissue's anchor clamps of adhesion material adhesion to comprise train wheel bridge 1 and 4 lower plates 2 for test organisms, described train wheel bridge 1 comprises the plummer 12 of upper mounted plate 11 and upper mounted plate 11 protrusions, described plummer 12 is the cylinder of round section, and each described lower plate 2 comprises the manhole 22 that matches with plummer in bottom plate 21 and the bottom plate.
Go up fixed orifices 13 around on average being arranged with four in 12 1 weeks of plummer on the described upper mounted plate 11, described bottom plate 21 is provided with and last fixed orifice 13 lower fixed hole 23 one to one.
Described upper mounted plate 11 is fixedlyed connected by the fixture (not shown) with bottom plate 12, when described fixture is magnet, Xi Fu two blocks of magnet are separately positioned in the corresponding last fixed orifice 13 and lower fixed hole 23 mutually, when described fixture is bolt, bolt passes lower fixed hole 23 and last fixed orifice 13, by nut lower plate 2 is fixed on the train wheel bridge 3.
The diameter of described cylindrical plummer 12 is 20mm, and the diameter of the through hole 22 of 4 described lower plates 2 is followed successively by 22mm, 24mm, 26mm and 28mm, is respectively applied to test the biological tissue section that thickness is 1mm, 2mm, 3mm and 4mm.
Describedly organize the material of biological tissue's anchor clamps of adhesion material adhesion to be selected from lightweight stainless steel, vitallium, titanium alloy, polypropylene or tygon for test organisms.
It is to be noted that the cross section of plummer can be circle, also can be other shapes such as square, triangle, and through hole matches with pole section and gets final product.
The course of work of described biological tissue's anchor clamps of organizing the adhesion material adhesion for test organisms is as follows:
At first select lower plate with suitable vias size according to the thickness of the biological tissue section of preparation, the biological tissue section center section is coated on the plummer, after biological tissue section smoothed, pass the through hole of lower plate, the marginal portion of biological tissue section is clamped between train wheel bridge and the lower plate, adjust train wheel bridge and lower plate, make fixed orifice and lower fixed hole corresponding and fixing mutually.After fixedly finishing, train wheel bridge is connected on the adhesion proving installation, carry out the adhesion test, after testing, unclamp fixture, biological tissue section is taken off, finish one and take turns test, successively the biological tissue section with same thickness carries out viscosity test at biological tissue's anchor clamps that the plummer diameter is followed successively by 20mm, 25mm, 30mm, 35mm and 40mm, the accuracy of verification msg, and the through-hole diameter of biological tissue's anchor clamps of all the other size plummers is analogized with reference to the embodiment of 20mm diameter plummer.

Claims (5)

1. one kind is used for biological tissue's anchor clamps that test organisms is organized the adhesion material adhesion, it is characterized in that, comprise train wheel bridge and lower plate, described train wheel bridge comprises the upper mounted plate of fixedlying connected with lower plate and the plummer of upper mounted plate protrusions, described lower plate comprise with the fixedly connected bottom plate of upper mounted plate and bottom plate in the through hole that matches with plummer.
2. a kind ofly organize biological tissue's anchor clamps of adhesion material adhesion for test organisms according to claim 1 is described, it is characterized in that described upper mounted plate is fixedlyed connected by fixture with bottom plate, described fixture is magnet or threaded connector.
3. according to the described a kind of biological tissue's anchor clamps of organizing the adhesion material adhesion for test organisms of claim 2, it is characterized in that, described upper mounted plate is provided with fixed orifice, described bottom plate is provided with and last fixed orifice lower fixed hole one to one, and last fixed orifice and lower fixed hole are used for arranging fixture.
4. according to the described a kind of biological tissue's anchor clamps of organizing the adhesion material adhesion for test organisms of claim 1, it is characterized in that, describedly organize biological tissue's anchor clamps of adhesion material adhesion to comprise a lower plate that above clear size of opening is different for test organisms.
5. according to the described a kind of biological tissue's anchor clamps of organizing the adhesion material adhesion for test organisms of claim 1, it is characterized in that, describedly organize the material of biological tissue's anchor clamps of adhesion material adhesion to be selected from lightweight stainless steel, vitallium, titanium alloy, polypropylene or tygon for test organisms.
CN 201320071949 2013-02-07 2013-02-07 Biological tissue clamp for testing adhesive power of biological tissue adhesion material Expired - Lifetime CN203132975U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201320071949 CN203132975U (en) 2013-02-07 2013-02-07 Biological tissue clamp for testing adhesive power of biological tissue adhesion material

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 201320071949 CN203132975U (en) 2013-02-07 2013-02-07 Biological tissue clamp for testing adhesive power of biological tissue adhesion material

Publications (1)

Publication Number Publication Date
CN203132975U true CN203132975U (en) 2013-08-14

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CN 201320071949 Expired - Lifetime CN203132975U (en) 2013-02-07 2013-02-07 Biological tissue clamp for testing adhesive power of biological tissue adhesion material

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107402180A (en) * 2017-06-22 2017-11-28 中国石油天然气集团公司 A kind of glue adhesive strength measurement apparatus
CN108956453A (en) * 2018-07-10 2018-12-07 瀚德(中国)汽车密封系统有限公司 A kind of removing of sealing element and test device
CN111579465A (en) * 2019-02-15 2020-08-25 中国科学院水生生物研究所 Device and method for measuring adhesive strength and dynamic falling process of attachment in liquid environment
CN112649625A (en) * 2020-12-08 2021-04-13 广东省医疗器械研究所 Method for detecting tissue mechanical property based on atomic force microscope

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107402180A (en) * 2017-06-22 2017-11-28 中国石油天然气集团公司 A kind of glue adhesive strength measurement apparatus
CN107402180B (en) * 2017-06-22 2020-01-07 中国石油天然气集团公司 Glue bonding strength measuring device
CN108956453A (en) * 2018-07-10 2018-12-07 瀚德(中国)汽车密封系统有限公司 A kind of removing of sealing element and test device
CN111579465A (en) * 2019-02-15 2020-08-25 中国科学院水生生物研究所 Device and method for measuring adhesive strength and dynamic falling process of attachment in liquid environment
CN111579465B (en) * 2019-02-15 2021-10-15 中国科学院水生生物研究所 Device and method for measuring adhesive strength and dynamic falling process of attachment in liquid environment
CN112649625A (en) * 2020-12-08 2021-04-13 广东省医疗器械研究所 Method for detecting tissue mechanical property based on atomic force microscope

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CX01 Expiry of patent term

Granted publication date: 20130814

CX01 Expiry of patent term