CN203060453U - Closed-loop insulin delivery device integrating micropump and microneedle array - Google Patents
Closed-loop insulin delivery device integrating micropump and microneedle array Download PDFInfo
- Publication number
- CN203060453U CN203060453U CN 201320057605 CN201320057605U CN203060453U CN 203060453 U CN203060453 U CN 203060453U CN 201320057605 CN201320057605 CN 201320057605 CN 201320057605 U CN201320057605 U CN 201320057605U CN 203060453 U CN203060453 U CN 203060453U
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- China
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- medicine storage
- microneedle array
- micropump
- battery
- drug administration
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Abstract
The utility model relates to a closed-loop insulin delivery device integrating a micropump and a microneedle array. The closed-loop insulin delivery device comprises a micropump device, the microneedle array and a drug delivery catheter connecting the microneedle array and the micropump device, wherein the micropump device comprises a battery cover, a battery, a master control circuit board, a force sensor, a servo motor, a drug delivery device body, a propelling screw, a drug storage device piston, a drug storage device and an external panel. The closed-loop insulin delivery device reduces a pain of a diabetic patient greatly; materials adopted by the microneedle array can be recovered more conveniently; and an environment cannot be polluted.
Description
Technical field
This utility model relates to a kind of insulin delivery device, the closed-loop insulin conveyer device of especially a kind of integrated Micropump and microneedle array.
Background technology
Diabetes are chronic diseases that a kind of common glucose metabolism and dyshormonia cause the general metabolism disorder then, and hyperglycemia is its main clinical characteristics.At present, the mode of most diabetics insulin injections is gradation injections clinically, generally is to inject every day three times, and respectively at injection in 20～30 minutes before the meal, the injection site generally was muscle.The mode of insulin gradation injection is simple and convenient, and the patient can oneself grasp very soon, but through long-term clinical observation and summary, its defective is also very outstanding, main performance is: 1) glycemic control instability, and hyperglycemia or hypoglycaem ic condition appear easily, bring misery and danger to the patient; 2) long-term blood glucose instability can cause the symptom of diabetics to increase the weight of gradually, also may cause various severe complications, jeopardizes patient's health and lives; 3) be difficult to the administration of insulin accurate quantification; The patient keenly feels obviously when 4) injecting, and is inconvenient to inject in public arenas such as social activities.
Along with the development of modern medical equipment industry, insulin pump has been born.Insulin pump has inevitably also brought the misery of injection as a kind of medical apparatus and instruments to the patient when having brought convenience, practicality to the patient.Insulin pump generally is made up of injection needle, conduit and syringe pump etc., and conduit links to each other with syringe pump, by the subcutaneous purpose that reaches drug release of the long-term implantation of injection needle.Up to now, must insulin could be injected in the body through painful and invasive injecting method.Because some safety problems that the implantation of syringe needle brings and environmental pollution also are difficult problems of puzzlement diabetics, in addition, because injection of insulin dosage is to set in advance, thereby can not accurately inject corresponding dosage according to blood glucose condition in the body in real time, thereby the hypoglycemia that also can cause or hyperglycemia.
Summary of the invention
This utility model provides a kind of closed-loop insulin conveyer device based on Micropump and microneedle array at the deficiency of existing insulin pump, can overcome pain problem, a safety and environmental protection difficult problem that insulin pump brings because of the implantation of syringe needle, also can overcome the problem that blood glucose condition is misfitted in insulin injection dosage and the body, be a kind of safer, succinct, better insulin delivery device of the suitability.
This utility model is realized by the following technical solutions:
This utility model comprises Micropump device, microneedle array and the infusion administering catheter that connects microneedle array and Micropump device.
Described Micropump device comprises battery cover, battery, master control circuit board, force transducer, servo motor, drug administration device body, augering screw, medicine storage piston, medicine storage and external panel.
Front end in drug administration device body one side is provided with for the draw-in groove that medicine storage is installed.
Be provided with servo motor in the rear end of drug administration device body one side the storehouse is installed, servo motor is installed in the storehouse, servo motor links to each other with augering screw, head at augering screw, a medicine storage piston is housed, this medicine storage piston can be free to slide along the inner chamber of medicine storage, at the afterbody of servo motor a force transducer is housed and is used for being captured in the power output signal that insulin is sent process.
Opposite side at the drug administration device body is provided with battery compartment, and battery is housed in battery compartment, is provided with battery cover in the battery compartment outer end, is used for self-contained battery, and battery cover adopts with the drug administration device body and is threaded; The two ends of battery are provided with lead-out wire, are used for powering to master control circuit board.
Described main control circuit is contained in the middle part of drug administration device body, is used for the loading system is controlled.
In the drug administration device structural body, an external panel also is housed, on be embedded with liquid crystal display and film key, liquid crystal display be used for to show relevant information, film key is used for loading parameter, system are opened and closed and arrange.
Head at medicine storage is provided with an infusion administering catheter, and the one end links to each other with medicine storage, and the other end links to each other with the package casing of microneedle array.
The beneficial effects of the utility model: because the length of microneedle array is shorter, only can thrust the epidermal area of skin histology, can not thrust nerve and the blood vessel of human skin tissue, thereby the patient does not have pain, the employed syringe needle of this insulin pump than routine, greatly reduced the misery of diabetics, the material that microneedle array adopts is all recyclable also more convenient, can not pollute environment.
Description of drawings
Fig. 1 is insulin Micropump apparatus structure sketch map;
Fig. 2 is insulin Micropump device A-A cut-away view;
Fig. 3 is closed-loop insulin conveyer device operation principle figure structure schematic representation.
The specific embodiment
The utility model is described in further detail below in conjunction with accompanying drawing.
As depicted in figs. 1 and 2, this utility model comprises Micropump device, microneedle array and the infusion administering catheter that connects microneedle array and Micropump device.
The Micropump apparatus structure comprises: battery cover 1, battery 2, master control circuit board 3, bonnet 4, force transducer 5, servo motor 6, drug administration device body 7, shell fixture 8, augering screw 9, medicine storage piston 10, medicine storage 11, infusion administering catheter 12, external panel 15.
Be provided with medicine storage in drug administration device body front side, drug administration device body front end has adopted the draw-in groove design, when medicine storage is installed, earlier medicine storage is embedded in the draw-in groove, then clockwise or be rotated counterclockwise 90 degree, medicine storage then is fixed on drug administration device body front end safely and reliably.
Be provided with servo motor at the medicine storage rear portion storehouse is installed, servo motor is installed in the storehouse, fixing by shell fixture 8, servo motor links to each other with augering screw, head at augering screw, a medicine storage piston is housed, and this piston can be free to slide along the inner chamber of medicine storage, a force transducer is housed at the back of servo motor is used for being captured in the power output signal that insulin is sent process.
Opposite side at the drug administration device body is provided with battery compartment, and battery is housed in battery compartment, is provided with battery cover in the battery compartment outer end, is used for self-contained battery, and battery cover adopts with the drug administration device body and is threaded.The two ends of battery are provided with lead-out wire, are used for powering to master control circuit board.
At the middle part of drug administration device body, a master control circuit board is housed, be used for the loading system is controlled, the corresponding drug administration device body of master control circuit board place is provided with bonnet 4.
In the drug administration device structural body, an external panel also is housed, on be embedded with liquid crystal display and film key, liquid crystal display be used for to show relevant information, film key is used for loading parameter, system's switching etc. is arranged.
Head at medicine storage is provided with an infusion administering catheter, and the one end links to each other with medicine storage, and the other end links to each other with the microneedle array package casing 13 of microneedle array 14.
Microneedle array is embedded on the microneedle array package casing that has cavity.Microneedle array is to adopt micro-nano technology to make, and is a kind of similar injection needle but the size micron order hollow needle array more much smaller than injection needle.Be 1CM at area
2Matrix material on, make 40 empty micropins, the empty micropin external diameter is that 80 μ m, internal diameter are 30 μ m, length is 400 μ m, the empty micropin head adopts pinnacle type design.Matrix material is silicon materials, and the cavity material can be macromolecular material, as politef.
As shown in Figure 3, during work, microneedle array is affixed on patient's skin somewhere, arm-type non-invasive blood sugar instrument is gathered patient's the interior blood glucose condition of body in real time, by wireless transmission method relevant parameter is reached the controller of Micropump system then, after the corresponding calculating of via controller, servomotor is just changeing the promotion augering screw and is travelling forward, thereby promoting the medicine storage piston travels forward along the medicine storage inner chamber, thereby promote the inner chamber that insulin to be injected enters the microneedle array package casing, the endoporus through microneedle array enters in the human body skin again.The servomotor counter-rotating drives augering screw and moves backward, thereby makes the medicine storage piston move backward along the medicine storage inner chamber, realizes reset motor.
Claims (1)
1. the closed-loop insulin conveyer device of an integrated Micropump and microneedle array comprises Micropump device, microneedle array and the infusion administering catheter that connects microneedle array and Micropump device, it is characterized in that:
Described Micropump device comprises battery cover, battery, master control circuit board, force transducer, servo motor, drug administration device body, augering screw, medicine storage piston, medicine storage and external panel;
Front end in drug administration device body one side is provided with for the draw-in groove that medicine storage is installed;
Be provided with servo motor in the rear end of drug administration device body one side the storehouse is installed, servo motor is installed in the storehouse, servo motor links to each other with augering screw, head at augering screw, a medicine storage piston is housed, this medicine storage piston can be free to slide along the inner chamber of medicine storage, at the afterbody of servo motor a force transducer is housed and is used for being captured in the power output signal that insulin is sent process;
Opposite side at the drug administration device body is provided with battery compartment, and battery is housed in battery compartment, is provided with battery cover in the battery compartment outer end, is used for self-contained battery, and battery cover adopts with the drug administration device body and is threaded; The two ends of battery are provided with lead-out wire, are used for powering to master control circuit board;
Described main control circuit is contained in the middle part of drug administration device body, is used for the loading system is controlled;
In the drug administration device body, an external panel also is housed, on be embedded with liquid crystal display and film key, liquid crystal display be used for to show relevant information, film key is used for loading parameter, system are opened and closed and arrange;
Head at medicine storage is provided with an infusion administering catheter, and the one end links to each other with medicine storage, and the other end links to each other with the package casing of microneedle array.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320057605 CN203060453U (en) | 2013-02-01 | 2013-02-01 | Closed-loop insulin delivery device integrating micropump and microneedle array |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320057605 CN203060453U (en) | 2013-02-01 | 2013-02-01 | Closed-loop insulin delivery device integrating micropump and microneedle array |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203060453U true CN203060453U (en) | 2013-07-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201320057605 Expired - Fee Related CN203060453U (en) | 2013-02-01 | 2013-02-01 | Closed-loop insulin delivery device integrating micropump and microneedle array |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203060453U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103083758A (en) * | 2013-02-01 | 2013-05-08 | 杭州电子科技大学 | Closed-loop insulin delivery device integrating micropump and microneedle array |
| WO2018201930A1 (en) * | 2017-05-04 | 2018-11-08 | 张艳 | Automatic medication injection device |
| CN109999275A (en) * | 2019-04-28 | 2019-07-12 | 甘甘医疗科技江苏有限公司 | A kind of insulin injection device based on intelligent distant control |
| CN111050822A (en) * | 2017-08-31 | 2020-04-21 | 贝克顿·迪金森公司 | System and method for detecting force applied during injection |
-
2013
- 2013-02-01 CN CN 201320057605 patent/CN203060453U/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103083758A (en) * | 2013-02-01 | 2013-05-08 | 杭州电子科技大学 | Closed-loop insulin delivery device integrating micropump and microneedle array |
| WO2018201930A1 (en) * | 2017-05-04 | 2018-11-08 | 张艳 | Automatic medication injection device |
| CN111050822A (en) * | 2017-08-31 | 2020-04-21 | 贝克顿·迪金森公司 | System and method for detecting force applied during injection |
| CN109999275A (en) * | 2019-04-28 | 2019-07-12 | 甘甘医疗科技江苏有限公司 | A kind of insulin injection device based on intelligent distant control |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130717 Termination date: 20160201 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |