CN203060019U - Biodegradable nanometer medicine carrying slow release intrauterine device - Google Patents

Biodegradable nanometer medicine carrying slow release intrauterine device Download PDF

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Publication number
CN203060019U
CN203060019U CN 201320012274 CN201320012274U CN203060019U CN 203060019 U CN203060019 U CN 203060019U CN 201320012274 CN201320012274 CN 201320012274 CN 201320012274 U CN201320012274 U CN 201320012274U CN 203060019 U CN203060019 U CN 203060019U
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CN
China
Prior art keywords
arm
transverse arm
sphere
intrauterine device
trailing arm
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN 201320012274
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Chinese (zh)
Inventor
张晓梅
王大新
吕芳
魏勉
顾方乐
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SCHOOL OF CLINICAL MEDICINE YANGZHOU UNIVERSITY
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SCHOOL OF CLINICAL MEDICINE YANGZHOU UNIVERSITY
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Priority to CN 201320012274 priority Critical patent/CN203060019U/en
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Publication of CN203060019U publication Critical patent/CN203060019U/en
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  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicinal Preparation (AREA)

Abstract

The utility model provides a biodegradable nanometer medicine carrying slow release intrauterine device and belongs to the technical field of contraception and birth control devices. The biodegradable nanometer medicine carrying slow release intrauterine device is characterized in that a flat umbrella-shaped structure is made of nanometer medicine carrying slow release degradable biological materials, the flat umbrella-shaped structure is formed by connection of a semi-circular transverse arm and a longitudinal arm, and the cross section of the transverse arm and the cross section of the longitudinal arm are circular shapes with equal diameters. Seven balls are attached to the transverse arm, four balls are attached to the longitudinal arm, two tail ends of the transverse arm and the tail end of the longitudinal arm are ball-shaped, the size of the balls is the same, radii of the balls are equal to the diameters of the transverse arm cross section and the longitudinal arm cross section, and the outer surface of the transverse arm, the outer surface of the longitudinal arm and the outer surfaces of the balls are provided with chitosan coatings. The biodegradable nanometer medicine carrying slow release intrauterine device does not need to be taken out after being placed into the uterine cavity, secondary operation is avoided, tail fiber structures are eliminated, partial stimulation and the side effect of retrograde infection on the uterine neck by the tail fibers are reduced, and the biodegradable nanometer medicine carrying slow release intrauterine device is simple and reasonable in structure, low in manufacturing cost and reliable in contraception effect and has good application prospect.

Description

Biodegradable nano carried medicine sustained-release intrauterine device
Technical field
This utility model relates to a kind of Biodegradable nano carried medicine sustained-release intrauterine device, belongs to the device technique field that avoids conception and control birth.
Background technology
The ancient Egyptian puts into the camel intrauterine with finger stone, prevents that camel from becoming pregnant in desert long-distance transport.Inspired by this, people learn and put into the effect that foreign body can have antifertility in the cavity of uterus.Accordingly, the mankind are constantly designing and are using optimal material to put into cavity of uterus to reach the contraception purpose, and be referred to as intrauterine device (Intrauterine Device, IUD).According to the difference of design concept, in utero birth control product and be widely used in clinical of three generations appears in the market in succession.The design of first generation IUD starts from 1909, is raw material with silkworm silk, plastics or rustless steel, claims the 'inertia' intrauterine device; Second generation IUD is called " activity " intrauterine device, plays a role by adding active component (copper ion, progestational hormone hormone), has improved contraceptive effect greatly; The appearance of Ji Nihuan can be considered to third generation intrauterine device, this birth control product has been abandoned the supporting structure of traditional intrauterine device, be made up of several copper sheathings of polyamide monofilament wear that can not absorb, an end of monofilament has a brief summary to be fixed in the flesh layer of bottom, uterus.But, applicable various in utero birth control product causes damage that side reactions such as hemorrhage, pain take place to inner membrance because of its support easily in the market, come off easily or the shift affects contraceptive effect simultaneously, in utero the birth control product is inserted the taking-up of must performing the operation again behind the uterine cavity at present, so clinical practice has certain limitation.
The utility model content
The purpose of this utility model is at above-mentioned the deficiencies in the prior art, thereby provide a kind of inserting to need not behind the uterine cavity to take out, reduced tailfiber simultaneously to cervix uteri local excitation and retrograde infection, the reliable Biodegradable nano carried medicine sustained-release of contraceptive effect intrauterine device.
The purpose of this utility model is achieved through the following technical solutions: Biodegradable nano carried medicine sustained-release intrauterine device, it is characterized in that, make the plane beveled structure by nano drug-carrying slow release degradable biomaterial, described plane beveled structure is connected and composed by a semicircle transverse arm and a trailing arm, the section of transverse arm and trailing arm is the circle of equal diameters, adhere to 7 spheres above the transverse arm, adhere to 4 spheres on the trailing arm, two ends terminal and trailing arm of transverse arm are sphere, the size of all spheres is consistent, the equal diameters of the radius of sphere and transverse arm and trailing arm section, described transverse arm, the outer surface of trailing arm and sphere has chitosan coat.
The diameter of described transverse arm and trailing arm section is 2mm.
Sphere on the described transverse arm evenly distributes, and the centre of sphere of the terminal sphere of transverse arm overlaps with the center of circle of transverse arm end face, and the height on 5 outstanding transverse arm surfaces of sphere is 2mm in the middle of the transverse arm.
Sphere on the described trailing arm evenly distributes, and the centre of sphere of the terminal sphere of trailing arm overlaps with the center of circle of trailing arm end face, and the height on the outstanding trailing arm surface of sphere is 1mm.
The length of described trailing arm is 20mm.
The length of described transverse arm is 31.4mm.
This utility model is made by nano drug-carrying slow release degradable biomaterial, itself has certain toughness and elasticity, and does not have the tailfiber structure, is convenient to insert uterine cavity.On the nano drug-carrying slow release degradable biomaterial levonorgestrel is arranged, medicine carrying total amount 52mg discharges 20 μ g every day, and material degradation time and medicament slow release time are controlled to be 5 years, can recover fertility naturally after material is fully degraded, and contraception influences completely reversibility.This utility model has avoided endometrium to the caused a series of uncomfortable reactions of the repulsion of traditional material (metal, plastics etc.) and side reaction, contraceptive effect, therapeutic effect are more definite, need not to take out after inserting uterine cavity, avoided second operation, remove the tailfiber structure, reduced the side reaction of tailfiber to cervix uteri local excitation and retrograde infection.This utility model design science, simple and reasonable, cheap for manufacturing cost, contraceptive effect is reliable, and is simple to operate, has a good application prospect.
Description of drawings
Fig. 1 is structural representation of the present utility model;
Fig. 2 inserts intrauterine sketch map for this utility model;
Among the figure: 1 semicircle transverse arm, 2 trailing arms, 3 spheres.
The specific embodiment
Biodegradable nano carried medicine sustained-release intrauterine device is made the plane beveled structure by nano drug-carrying slow release degradable biomaterial, and the plane beveled structure is connected and composed by a semicircle transverse arm and a trailing arm.
The section of transverse arm and trailing arm is the circle of equal diameters, and the diameter of transverse arm and trailing arm section is 2mm.The length of trailing arm is 20mm, and the length of transverse arm is 31.4mm.
Adhere to 7 spheres above the transverse arm, the sphere on the transverse arm evenly distributes, and the centre of sphere of the terminal sphere of transverse arm overlaps with the center of circle of transverse arm end face, and the height on 5 outstanding transverse arm surfaces of sphere is 2mm in the middle of the transverse arm.
Adhere to 4 spheres on the trailing arm, the sphere on the trailing arm evenly distributes, and the centre of sphere of the terminal sphere of trailing arm overlaps with the center of circle of trailing arm end face, and the height on the outstanding trailing arm surface of sphere is 1mm.
Two ends terminal and trailing arm of transverse arm are sphere, and the size of all spheres is consistent, the equal diameters of the radius of sphere and transverse arm and trailing arm section, and the outer surface of transverse arm, trailing arm and sphere has chitosan coat.
This utility model does not have the tailfiber structure, inserts to need not behind the uterine cavity to take out, and has avoided second operation, has removed the tailfiber structure, has reduced the side reaction of tailfiber to cervix uteri local excitation and retrograde infection.Sphere can increase the surface area of nano controlled-release material, increases local resistance, prevents from coming off.Two ends terminal and trailing arm of transverse arm are sphere, effectively to prevent the birth control apparatus down uterine cavity that pauses, increase local resistance simultaneously, prevent from coming off.

Claims (6)

1. Biodegradable nano carried medicine sustained-release intrauterine device, it is characterized in that, make the plane beveled structure by nano drug-carrying slow release degradable biomaterial, described plane beveled structure is connected and composed by a semicircle transverse arm and a trailing arm, the section of transverse arm and trailing arm is the circle of equal diameters, adhere to 7 spheres above the transverse arm, adhere to 4 spheres on the trailing arm, two ends terminal and trailing arm of transverse arm are sphere, the size of all spheres is consistent, the equal diameters of the radius of sphere and transverse arm and trailing arm section, described transverse arm, the outer surface of trailing arm and sphere has chitosan coat.
2. Biodegradable nano carried medicine sustained-release intrauterine device according to claim 1 is characterized in that, the diameter of described transverse arm and trailing arm section is 2mm.
3. Biodegradable nano carried medicine sustained-release intrauterine device according to claim 1, it is characterized in that, sphere on the described transverse arm evenly distributes, and the centre of sphere of the terminal sphere of transverse arm overlaps with the center of circle of transverse arm end face, and the height on 5 outstanding transverse arm surfaces of sphere is 2mm in the middle of the transverse arm.
4. Biodegradable nano carried medicine sustained-release intrauterine device according to claim 1, it is characterized in that, sphere on the described trailing arm evenly distributes, and the centre of sphere of the terminal sphere of trailing arm overlaps with the center of circle of trailing arm end face, and the height on the outstanding trailing arm surface of sphere is 1mm.
5. Biodegradable nano carried medicine sustained-release intrauterine device according to claim 1 is characterized in that, the length of described trailing arm is 20mm.
6. Biodegradable nano carried medicine sustained-release intrauterine device according to claim 1 is characterized in that, the length of described transverse arm is 31.4mm.
CN 201320012274 2013-01-10 2013-01-10 Biodegradable nanometer medicine carrying slow release intrauterine device Expired - Fee Related CN203060019U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201320012274 CN203060019U (en) 2013-01-10 2013-01-10 Biodegradable nanometer medicine carrying slow release intrauterine device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 201320012274 CN203060019U (en) 2013-01-10 2013-01-10 Biodegradable nanometer medicine carrying slow release intrauterine device

Publications (1)

Publication Number Publication Date
CN203060019U true CN203060019U (en) 2013-07-17

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN 201320012274 Expired - Fee Related CN203060019U (en) 2013-01-10 2013-01-10 Biodegradable nanometer medicine carrying slow release intrauterine device

Country Status (1)

Country Link
CN (1) CN203060019U (en)

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20130717

Termination date: 20200110

CF01 Termination of patent right due to non-payment of annual fee