CN203059897U - Renal artery orbit radio frequency ablation electrode catheter - Google Patents
Renal artery orbit radio frequency ablation electrode catheter Download PDFInfo
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- CN203059897U CN203059897U CN 201220289499 CN201220289499U CN203059897U CN 203059897 U CN203059897 U CN 203059897U CN 201220289499 CN201220289499 CN 201220289499 CN 201220289499 U CN201220289499 U CN 201220289499U CN 203059897 U CN203059897 U CN 203059897U
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Abstract
The utility model discloses a renal artery orbit radio frequency ablation electrode catheter. The renal artery orbit radio frequency ablation electrode catheter is used for improving a therapeutic effect of the hypertension and a therapeutic effect of the intractable hypertension, and is safe and convenient to use. The renal artery orbit radio frequency ablation electrode catheter is provided with a spiral orbit guide wire and a radio frequency ablation catheter. The far end of the spiral orbit guide wire is a section which is in a spiral shape. The radio frequency ablation catheter slides along the helix of the spiral orbit guide wire. Compared with the prior art, a spiral spring at the far end of the spiral orbit guide wire is released to be in a spiral circle shape, is arranged inside a renal artery blood vessel, and is tightly attached to the inner wall of the renal artery blood vessel, the radio frequency ablation catheter slides along the helix of the spiral orbit guide wire to carry out radio frequency ablation, beaks a sympathetic nerve which is attached to the inner wall of the renal artery blood vessel, the purpose of curing the intractable hypertension is achieved, a doctor can easily control the radio frequency ablation catheter to carry out the radio frequency ablation on different positions of a spiral circle, operation is convenient, damage to a renal artery is little, an operation is safe, and an therapeutic effect is remarkably improved.
Description
Technical field
This utility model relates to a kind of structure of medical apparatus and instruments, particularly a kind of renal artery radio-frequency ablation electrode conduit that is used for the treatment of intractable hypertension.
Background technology
Intractable hypertension is more common clinically, paathogenic factor is numerous, pathogenesis is indeterminate, medication effect is very poor, diagnosis and treatment means are still not mature enough, become one of great difficult problem of hypertension therapeutic, and this patient is usually with other cardiovascular diseasess' risk factor, as coronary heart disease, diabetes, heart failure, hyperlipidemia, nephropathy, peripheral arterial disease, apoplexy, left ventricular hypertrophy etc.In hypertensive various complication, the most remarkable with the infringement of the heart, brain, kidney, for example according to World Health Organization's statistics, 50% cardiovascular disease is caused by hypertension.At present because pressure value increases, the cardiovascular and cerebrovascular vessel event takes place cause the annual whole world about 7,100,000 of dead number.And in China crowd's more than 40 years old the cause of death, heart disease and cerebrovascular are classified the-position and the 3rd respectively as, and first risk factor of total death is hypertension.
Medical circle thinks that always sympathetic activation and the hypertension of kidney are in close relations.When the sympathetic nerve of kidney was overexcited, renal blood vessels was shunk, and reduced the excretion of kidney, make moisture and salt retention in vivo, promote the renal secretion feritin simultaneously, caused the increase of the nervous plain II of blood medium vessels and aldosterone, then two kinds of materials, the factor of hypertension just.
In March, 2009, in the 58th science conference of american heart institute (ACC) that Global Home Textiles is held, professor Krum of Australia Monash university proposed a kind of brand-new treatment intractable hypertension non-pharmaceutical method---radio-frequency (RF) ablation is removed the sympathetic nerve of domination kidney, namely by femoral artery puncture and angiography, special radio-frequency (RF) ablation conduit is imported renal artery, send the sympathetic nerve of radio-frequency (RF) energy destruction domination kidney and treat hypertension, thereby significantly reduce intractable hypertension patient's blood pressure.The theoretical basis of this blood pressure lowering treatment new method is: the sympathetic nerve of kidney imports the superficial place that is distributed in renal artery wall below with efferent fiber into, its active and hypertensive generation and keep closely relatedly carry out in the renal artery part that radio-frequency (RF) ablation can be damaged the kidney sympathetic nerve and the nervous tissue of not involving other abdominal paries, pelvic cavity or lower limb.Thereby the denervated method safety of this kidney is good.The observation of process December is studied as can be known in the curative effect aspect, and when treating back 1 month, patient's blood pressure obviously reduces, and its blood pressure further reduces in the time of 3 months, and the effect that blood pressure reduces in the time of 1 year is highly significant still, does not also find tangible neuranagenesis simultaneously.
This shows that blood pressure is mainly regulated by kidney.Nowadays the thinking of hypertension therapy is to reduce angiotensin by medicine, yet the sympathetic nerve that spreads all on the renal artery also is to cause hypertensive arch-criminal.If these nerves are too active, the secretion feritin is too much too fast, just be enough to the effect that " payment " falls the medicine blood pressure lowering.Renal artery inner membrance radio-frequency ablation procedure is eliminated exactly and thisly orthosympatheticly is overexcited.Easy and the safety of this therapy method.During treatment, the doctor carries out radio-frequency (RF) ablation by conduit to the sympathetic nerve that spreads all on the renal artery tube wall down image-guided, cuts away partial nerve, thereby reduces the function of sympathetic nerve conducts information.Renin secretion thereby minimizing, angiotensin will reduce, and blood pressure reduces.
Also there is not a kind of medical apparatus and instruments really to be used for the clinical treatment intractable hypertension at present.The finding report all also only limits to the experimental stage.One of report is by handling a handle far-end stretch bending of conduit to be made it to fit with the renal artery blood vessel wall, a turn-knob on the turning handle is controlled the rotation of ablation catheter far-end simultaneously, thereby mobile ablation locations, reach at different parts and melt, because distal end of catheter is very soft, the rotational angle of ablation catheter far-end can not keep consistent with the rotational angle of control turn-knob during turning handle, cause the actual ablation locations can not be in full accord with the ablation locations of expectation, may influence therapeutic effect.Two of report is to adopt the ARR ablation catheter for the treatment of to melt renal artery, the treatment intractable hypertension, and this kind conduit diameter is thicker, handle inconvenience in the renal artery blood vessel, and it is bigger to melt area, can cause bigger damage to renal artery.
Summary of the invention
The purpose of this utility model provides a kind of renal artery orbital radio frequency melting electrode catheter, and the technical problem that solve is to improve the effect for the treatment of hypertension intractable hypertension, and safety, convenience.
This utility model is by the following technical solutions: a kind of renal artery orbital radio frequency melting electrode catheter, described renal artery orbital radio frequency melting electrode catheter is provided with helical orbit seal wire and radio-frequency (RF) ablation conduit, the helical orbit wire distal is one section helical form, and the radio-frequency (RF) ablation conduit slides along the helix of helical orbit seal wire.
Radio-frequency (RF) ablation distal end of catheter of the present utility model has electrode retaining collar, and electrode retaining collar slides along the helix of helical orbit seal wire.
Radio-frequency (RF) ablation conduit of the present utility model is provided with catheter body, and the far-end outer rim of catheter body embeds the electrode retaining collar that annular is arranged, and the near-end of catheter body passes contiguous block, is connected with the far-end of seat.
Catheter body of the present utility model is provided with coaxial pipe, internal diameter 0.46mm, coaxial pipe outer from far-end to near-end, order is equipped with soft tip, electrode retaining collar, first section sleeve pipe, second section sleeve pipe, the 3rd section sleeve pipe; Described soft tip is taper, long 10mm, and maximum outside diameter is 1.50-1.60mm, selects flexible plastic PU80AE pipe or metal coil spring for use; Described electrode retaining collar is platinumiridio or platinum ring, long 1-3mm, external diameter 1.52mm, internal diameter 1.40mm; The hardness of described first section sleeve pipe, second section sleeve pipe, the 3rd section sleeve pipe is from distal-to-proximal hardening gradually, and its material is polyurethane, nylon elastomer, high density polyethylene (HDPE) or nylon.
The plastic layer that coaxial pipe of the present utility model is made of polyurethane, nylon elastomer or nylon, the metal spring and the metallic steel silk screen that embed are wherein formed; One section 30mm length range of described plastic layer distal end external diameter 0.61mm, the remainder external diameter is 0.66mm; Described metal spring adopts the stainless steel silk of diameter 0.025mm, turns to external diameter 0.48mm, pitch 0.076-0.127mm, and length is 1200 helical spring; It is the stainless steel silk of 0.0127mm * 0.038mm that described metallic steel silk screen adopts the cross section, is woven into density for contain the steel wire in 55-120 cross point along coaxial pipe axis per inch length.
Helical orbit seal wire of the present utility model is provided with the wire guide axle, the wire guide axle adopts the niti-shaped memorial alloy silk of diameter 0.36-0.46mm, and 30-50mm turns to coil spring shape at the distance distal end, and its external diameter is 4-6mm, pitch 15-20mm, length is 30-40mm.
Wire guide axle far-end of the present utility model is nested with and is connected with the spring-guide wire head, and the spring-guide wire head adopts stainless steel silk or the platinum wire of diameter 0.1mm, turns to external diameter 0.36mm, pitch 0.1-0.127mm, and length is the coil spring shape of 20-40mm.
Helical orbit seal wire of the present utility model is provided with taenidium and raw silk rings; Described taenidium adopts the niti-shaped memorial alloy silk of diameter 0.36-0.41mm, turns to coil spring shape at distance distal end 30-50mm place, and helical spring external diameter is slightly less than the diameter of renal artery blood vessel, and pitch is 15-20mm, and long is 30-40mm; Described raw silk rings adopts the stainless steel silk of diameter 0.41-0.46mm; Described raw silk rings and taenidium are set up in parallel, and at one section of coil spring shape and its axis coaxle, far-end is welded to connect.
The far-end of taenidium of the present utility model and raw silk rings is nested with and is connected with the conductive filament head spring, and the conductive filament head spring adopts stainless steel silk or the platinum wire of diameter 0.1mm, turns to external diameter 0.36mm, pitch 0.1-0.127mm, and length is the coil spring shape of 20-40mm.
The near-end of seat of the present utility model connects the handle combination through straight-through haemostatic valve, and the near-end of described raw silk rings is connected in the handle combination, and the handle combination is provided with control to the mechanism of the stretching silk of near-end.
This utility model compared with prior art, the spiral spring of helical orbit wire distal is released round in the shape of a spiral, in the renal artery blood vessel and be close to the renal artery blood vessel, the radio-frequency (RF) ablation conduit carries out radio-frequency (RF) ablation along the helix slip of helical orbit seal wire, interrupt the sympathetic nerve that is attached to the renal artery blood vessel, reach the purpose for the treatment of intractable hypertension, the doctor controls the radio-frequency (RF) ablation conduit easily and melts at the diverse location of spiral coil, easy to operate, little to injury of renal artery, operation safety significantly improves therapeutic effect.
Description of drawings
Fig. 1 is the structural representation of renal artery orbital radio frequency melting electrode catheter of the present utility model ().
Fig. 2 is the structural representation of helical orbit seal wire of the present utility model ().
Fig. 3 is guiding catheter structural representation of the present utility model.
Fig. 4 is radio-frequency (RF) ablation guide-tube structure sketch map of the present utility model.
Fig. 5 is contiguous block structural representation of the present utility model.
Fig. 6 is the A-A cutaway view of Fig. 5.
Fig. 7 is catheter body cutaway view of the present utility model.
Fig. 8 is coaxial pipe cutaway view of the present utility model.
Fig. 9 is helical orbit seal wire delivery conduit structural representation of the present utility model.
Figure 10 is the structural representation of Y type haemostatic valve of the present utility model.
Figure 11 is the structural representation of helical orbit seal wire of the present utility model (two).
Figure 12 is the structural representation of straight-through haemostatic valve of the present utility model.
Figure 13 is the structural representation of renal artery orbital radio frequency melting electrode catheter of the present utility model (two).
Figure 14 is handle combinative structure sketch map of the present utility model.
Figure 15 is the cutaway view of handle casing of the present utility model.
Figure 16 is the A-A cutaway view of Figure 15.
Figure 17 is the cutaway view of push rod of the present utility model.
Figure 18 is the left view of Figure 17.
Figure 19 is the cutaway view of pusher body of the present utility model.
Figure 20 is the C-C cutaway view of Figure 19.
Figure 21 is the D-D cutaway view of Figure 19.
Figure 22 is the front view of slide bar.
Figure 23 is the left view of Figure 21.
Figure 24 is the E-E cutaway view of Figure 22.
Figure 25 is the F-F cutaway view of Figure 23.
Figure 26 is handle assembly drawing of the present utility model.
Figure 27 is the front view of spring leaf.
Figure 28 is the vertical view of Figure 27.
The specific embodiment
Below in conjunction with drawings and Examples this utility model is described in further detail.
Embodiment one
As shown in Figure 1, renal artery orbital radio frequency melting electrode catheter 100 of the present utility model is provided with helical orbit seal wire 10, guiding catheter 20, helical orbit seal wire delivery conduit 30 and radio-frequency (RF) ablation conduit 40.Helical orbit seal wire 10 is arranged in helical orbit seal wire delivery conduit 30 or the radio-frequency (RF) ablation conduit 40, forms sliding-contact with helical orbit seal wire delivery conduit 30 or radio-frequency (RF) ablation conduit 40.Helical orbit seal wire delivery conduit 30 or radio-frequency (RF) ablation conduit 40 are arranged in the guiding catheter 20, form sliding-contact with guiding catheter 20.Guiding catheter 20 near-ends are connected with Y type haemostatic valve 50, and radio-frequency (RF) ablation conduit 40 near-ends are connected with another Y type haemostatic valve 50.
As shown in Figure 2, helical orbit seal wire 10 is made up of the spring-guide wire head 11 that is positioned at far-end and wire guide axle 12.Spring-guide wire head 11 adopts stainless steel silk or the platinum wire of diameter 0.004 ＂ (0.1mm), turns to external diameter 0.014 ＂ (0.36mm), pitch 0.004 ＂-0.005 ＂ (0.1-0.127mm), and length is the coil spring shape spring-guide wire head 11 of 20-40mm.Wire guide axle 12 adopts the niti-shaped memorial alloy silk of diameter 0.014 ＂-0.018 ＂ (0.36-0.46mm), one section at distance wire guide axle 12 distal end 30-50mm turns to coil spring shape, its external diameter is 4-6mm, pitch 15-20mm, length is 30-40mm, the axis of coil spring shape is coaxial with wire guide axle 12, and the total length of wire guide axle 12 is 2000mm.Spring-guide wire head 11 is nested with along the axis of helical orbit seal wire 10 and is connected wire guide axle 12 far-ends, and is welded to connect with the far-end of wire guide axle 12.
As shown in Figure 3, guiding catheter 20 long 50cm are connected to form by catheter body 21 and the catheter block 22 that the 6:1 standard Luer joint that is positioned at near-end constitutes.Catheter body 21 external diameter 2.66mm, internal diameter 2.13mm, constituted by internal layer, skin and middle stainless steel cloth, internal layer adopts polytetrafluoroethylene PTFE, the outer U.S. NEU Specialty Engineered Material that adopts, it is the stainless steel silk of 0.0013 ＂-0.005 ＂ (0.033-0.127mm) that elastomer PEBAX or the nylon of LLC company, stainless steel cloth adopt the silk footpath, and being woven into density is the stainless (steel) wire that catheter body 21 per inch length contain 75-120 cross point.The distal portions of catheter body 21 is used for being inserted in the renal artery, sets up a passage, is convenient to helical orbit seal wire 10, helical orbit seal wire delivery conduit 30, radio-frequency (RF) ablation conduit 40 and is inserted in the renal artery by this passage.The near-end of catheter body 21 puts in the remote stomidium of conduit Cuo 22, and the far-end of conduit Cuo 22 and catheter body 21 near-ends are welded to connect by injection molding way.
As shown in Figure 4, radio-frequency (RF) ablation conduit 40 is made up of seat 44, adapter 45 and electrode retaining collar 47 that catheter body 41, contiguous block 42, wire socket 43,6:1 standard Luer joint constitute.It is that 1.50-1.60mm, internal diameter are the multiple tube of 0.46mm that catheter body 41 adopts external diameter, and the far-end outer rim of catheter body 41 embeds the electrode retaining collar 47 that annular is arranged, and the near-end of catheter body 41 passes contiguous block 42, is connected with the viscose glue mode with the far-end of seat 44.Electrode retaining collar 47 is long 1-3mm, external diameter 0.060 ＂ (1.52mm), the platinumiridio of internal diameter 0.055 ＂ (1.40mm) or platinum ring.Wire socket 43 is tubulose, and its far-end is connected in the hole of contiguous block 42, and near-end is connected with adapter 45, and wire socket 43 is connected with the method for contiguous block 42, adapter 45 usefulness viscose glues.Wire socket 43 is used for radio-frequency (RF) energy transfer wire 418, critesistor or thermocouple 419 and passes wherein.Adapter 45 is 4 needle connectors, is used for radio-frequency (RF) energy transfer wire 418, critesistor or thermocouple 419 are electrically connected with external equipment.
As shown in Figure 5 and Figure 6, have a through hole on the contiguous block 42, the axis of through hole is along the length dimension direction of contiguous block 42, and another hole is communicated with through hole, and the axis in another hole is acute angle along the axis of proximal direction and through hole.Contiguous block 42 is used for glueing joint connecting duct body 41 and wire socket 43, and catheter body 41 passes through hole, and wire socket 43 far-ends put in another hole.
As shown in Figure 7, catheter body 41 is the electrode retaining collar 47 among Fig. 4 by coaxial pipe 411, soft most advanced and sophisticated 416, electrode retaining collar 412(), first section sleeve pipe 413, second section sleeve pipe 414, the 3rd section sleeve pipe 415, handle tube 417, radio-frequency (RF) energy transfer wire 418, critesistor or thermocouple 419 form.Coaxial pipe 411 is long 1000mm, internal diameter 0.018 ＂ (0.46mm), and one section 30mm length range of distal end external diameter 0.024 ＂ (0.61mm), remainder external diameter are the multiple tube of 0.026 ＂ (0.66mm).Coaxial pipe 411 outer from far-end to near-end, order is equipped with soft most advanced and sophisticated 416, electrode retaining collar 412, first section sleeve pipe 413, second section sleeve pipe 414,415, the three sections sleeve pipes of the 3rd section sleeve pipe, the 415 outer handle tubes 417 that are equipped with.The hop count of sleeve pipe can be less than or more than three sections.
Soft most advanced and sophisticated 416 profiles are taper, and long 10mm, maximum outside diameter are 1.50-1.60mm, can select flexible plastic U.S. NEU Specialty Engineered Material for use, PU80AE pipe or the metal coil spring of LLC company.Electrode retaining collar 412 is platinumiridio or platinum ring, long 1-3mm, external diameter 0.060 ＂ (1.52mm), internal diameter 0.055 ＂ (1.40mm).First section sleeve pipe 413, second section sleeve pipe 414, the 3rd section sleeve pipe 415 external diameters, 0.060 ＂ (1.52mm), internal diameter 0.026 ＂-0.030 ＂ (0.66-0.76mm), the hardness of sleeve pipe is from distal-to-proximal hardening gradually, and its material is polyurethane PU, A Kema nylon elastomer PEBAX, high density polyethylene or nylon.Its objective is the hardness segmentation gradual change that makes catheter body 41, the relative near-end of far-end is softer, and the torsion that strengthens catheter body 41 simultaneously transmits performance.Handle tube 417 long 50mm, external diameter 2mm, internal diameter 1.65mm adopts nylon tube or stainless steel tube.
The near-end of catheter body 41 has the hole, is used for radio-frequency (RF) energy transfer wire 418 is introduced, and the gap between coaxial pipe 411 and each section sleeve pipe, far-end is solder-connected on the inwall of electrode retaining collar 412.By this hole with the quick resistance of thermoelectricity or thermocouple 419 transmission lines the gap between coaxial pipe 411 and each section sleeve pipe, be electrically connected to the critesistor that is positioned at electrode retaining collar 412 or the temperature element of thermocouple.The near-end of radio-frequency (RF) energy transfer wire 418, thermoelectric quick resistance or thermocouple 419 is electrically connected with adapter 45 through another hole, the wire socket 43 of contiguous block 42.
Make catheter body 41 and adopt hot-fluid change method, coaxial pipe 411 is nested with on plug, after soft most advanced and sophisticated 416, electrode retaining collar 412, first section sleeve pipe 413, second section sleeve pipe 414, the 3rd section sleeve pipe 415, handle tube 417 be nested with combination, stream becomes an integral body, hot-fluid change machine adopts the U.S. US AT INC Reflow-22 of company thermal change machine, and technological parameter is temperature 420F, speed 0.25 cel, make catheter body 41, take out plug behind the natural cooling.
As shown in Figure 8, the plastic layer 4111 that is made of PU, PEBAX or nylon of coaxial pipe 411, the metal spring 4112 and the metallic steel silk screen 4113 that embed are wherein formed.Plastic layer 4111 distal ends, one section 30mm length range external diameter 0.024 ＂ (0.61mm), remainder external diameter are 0.026 ＂ (0.66mm).Metal spring 4112 adopts the stainless steel silk of diameter 0.001 ＂ (0.025mm), turns to external diameter 0.019 ＂ (0.48mm), pitch 0.003 ＂-0.005 ＂ (0.076-0.127mm), and length is 1200 helical spring.It is the stainless steel silk of 0.0005 ＂ * 0.0015(0.0127mm * 0.038mm) that metallic steel silk screen 4113 adopts cross sections, is woven into density for contain the steel wire in 55-120 cross point along coaxial pipe 411 axis per inch length.Adopt hot-fluid change method, metal spring 4112 and metallic steel silk screen 4113 are nested with on plug, be nested with plastic layer 4111 again, hot-fluid change machine adopts the U.S. US AT INC Reflow-22 of company thermal change machine, technological parameter is temperature 400F, speed 0.25 cel becomes plastic layer 4111, metal spring 4112 and metallic steel silk screen 4113 hot-fluids into coaxial pipe 411 integral body, takes out plug behind the natural cooling.
As shown in Figure 9, helical orbit seal wire delivery conduit 30 effective lengths are 55cm, by delivery conduit body 31 be positioned at the delivery conduit seat 32 that the 6:1 standard Luer joint of near-end constitutes and connect to form.Delivery conduit body 31 adopts external diameter 2mm, the high density polyethylene pipe of internal diameter 1.04mm.The near-end of delivery conduit body 31 and delivery conduit seat 32 far-ends are welded to connect by the injection moulding mode.
As shown in figure 10, Y type haemostatic valve 50 and another Y type haemostatic valve 50 are the Y type haemostatic valve joint that U.S. Qosina company produces, and length is 70mm.The far-end of Y type haemostatic valve 50 puts in and is connected in the proximal orifice of catheter block 22.The far-end of another Y type haemostatic valve 50 connects the near-end of radio-frequency (RF) ablation conduit 40.
During operation, at first, the superslide seal wire that the doctor adopts a prior art drives in the wrong direction from the person's of undergoing surgery femoral artery and inserts far-end to the renal artery blood vessel.Catheter block 22 at guiding catheter 20 connects Y shape haemostatic valve 50, and the coaxial superslide seal wire that is inserted in of the far-end of guiding catheter 20 is fed through the renal artery porch along the superslide seal wire with the far-end of guiding catheter 20, withdraws from the superslide seal wire.
Secondly, the near-end of helical orbit seal wire 10 is inserted from the hole of helical orbit seal wire delivery conduit 30 far-ends, stretch out from base 32 through delivery conduit body 31, hold the near-end of helical orbit seal wire 10, the coil spring shape of helical orbit seal wire 10 far-ends is approximated to linearity draws in the remote stomidium of helical orbit seal wire delivery conduit 30.
Again, helical orbit seal wire delivery conduit 30 far-ends that helical orbit seal wire 10 is housed are inserted in the hole of guiding catheter 20 near-ends, through guiding catheter 20, push helical orbit seal wire delivery conduit 30 to far-end, make the far-end of helical orbit seal wire delivery conduit 30 to the far-end renal artery porch of guiding catheter 20.Because the effective length of guiding catheter 20 is 50cm, the length of Y type haemostatic valve 50 is 70mm, the effective length of helical orbit seal wire delivery conduit 30 is 55cm, the length sum that is shorter in length than guiding catheter 20 and Y type haemostatic valve 50 of helical orbit seal wire delivery conduit 30, when having guaranteed the distal-most end to far-end propelling movement helical orbit seal wire delivery conduit 30 to guiding catheter 20, helical orbit seal wire delivery conduit 30 can not stretch out guiding catheter 20 damage renal artery blood vessels.
Then, the coil spring shape of the helical orbit seal wire 10 of far-end is pushed out helical orbit seal wire delivery conduit 30 and guiding catheter 20, to the renal artery blood vessel, the spring-guide wire head 11 of helical orbit seal wire 10 far-ends is stretched in the branch of renal artery blood vessel, extract helical orbit seal wire delivery conduit 30 from near-end.Because the diameter of people's renal artery blood vessel is 4-6mm, the diameter of the spiral coil of helical orbit seal wire 10 also is 4-6mm, after extracting helical orbit seal wire delivery conduit 30 from near-end, the spiral spring of helical orbit seal wire 10 far-ends is released round in the shape of a spiral, in the renal artery blood vessel and be close to the renal artery blood vessel.
At last, operative doctor inserts the near-end of helical orbit seal wire 10 in the hole of radio-frequency (RF) ablation conduit 40 far-ends, pass seat 44, one near-end that holds helical orbit seal wire 10 keeps maintaining static, another hands pushes radio-frequency (RF) ablation conduit 40 to far-end, and radio-frequency (RF) ablation conduit 40 is along helical orbit seal wire 10, internal channel is advanced to far-end in the hole of guiding catheter 20.When the pushed spiral coil to helical orbit seal wire 10 of radio-frequency (RF) ablation conduit 40, because the far-end of radio-frequency (RF) ablation conduit 40 is very soft, continuation is during to propelling movement radio-frequency (RF) ablation conduit 40 far away, and the electrode retaining collar 47 of radio-frequency (RF) ablation conduit 40 far-ends will move as helical form to far-end along with the spiral coil of radio-frequency (RF) ablation conduit 40 along helical orbit seal wire 10.The electrode retaining collar 47 of radio-frequency (RF) ablation conduit 40 far-ends every to far-end move one uniformly between distance do a short stay, the startup radiofrequency generator discharges and melts, after electrode retaining collar 47 rotates a circle along helical orbit seal wire 10, blood vessel wall also just by even septal ablation one week, thereby interrupted the sympathetic nerve that is attached to the renal artery blood vessel fully.Also can select large-spacing and the mode that is less than all spirals to melt, and only part melt the sympathetic nerve that friendship is attached to the renal artery blood vessel, can satisfy doctor's operation intention fully according to therapeutic scheme.Simultaneously, because the spring-guide wire head 11 of helical orbit seal wire 10 is stuck in the arteriorenal branch vessel, can prevent that the phenomenon that causes helical orbit seal wire 10 to rotate from taking place when far-end pushes radio-frequency (RF) ablation conduit 40.
Embodiment two
As shown in figure 13, renal artery orbital radio frequency melting electrode catheter 200 of the present utility model is provided with helical orbit seal wire 60, guiding catheter 20, radio-frequency (RF) ablation conduit 40 and handle combination 80.Helical orbit seal wire 60 is arranged in the radio-frequency (RF) ablation conduit 40, forms sliding-contact with radio-frequency (RF) ablation conduit 40.Radio-frequency (RF) ablation conduit 40 is arranged in the guiding catheter 20, forms sliding-contact with guiding catheter 20.Guiding catheter 20 near-ends are connected with Y type haemostatic valve 50, and radio-frequency (RF) ablation conduit 40 near-ends are connected with straight-through haemostatic valve 70.Handle combination 80 connects the near-end of straight-through haemostatic valve 70.
As shown in figure 11, helical orbit seal wire 60 is different with helical orbit seal wire 10 structures of embodiment one.Helical orbit seal wire 60 is made up of conductive filament head spring 61, taenidium 62 and raw silk rings 63.Conductive filament head spring 61 adopts stainless steel silk or the platinum wire of diameter 0.004 ＂ (0.1mm), turns to external diameter 0.014 ＂ (0.36mm), pitch 0.004 ＂-0.005 ＂ (0.1-0.127mm), and length is the spiral spring of 20-40mm.Taenidium 62 length are 2000mm, adopt the niti-shaped memorial alloy silk of diameter 0.014 ＂-0.016 ＂ (0.36-0.41mm), begin to turn to coil spring shape at distance distal end 30-50mm place.The spring outside coil diameter of helical orbit seal wire 60 is slightly less than the internal diameter of renal artery blood vessel, and pitch is 15-20mm, and long is 30-40mm.Raw silk rings 63 adopts the stainless steel silk of diameter 0.016 ＂-0.018 ＂ (0.41-0.46mm), and long is 30-40mm.Raw silk rings 63 is set up in parallel with taenidium 62, at one section of coil spring shape and its axis coaxle.Conductive filament head spring 61 is inserted in the far-end of taenidium 62 and raw silk rings 63 along the axis of helical orbit seal wire 60, and is welded to connect with the far-end of taenidium 62 and raw silk rings 63.
As shown in figure 12, straight-through haemostatic valve 70 adopts the straight type haemostatic valve of U.S. Qosina company production.
As shown in figure 14, handle combination 80 is made up of distal seat 81, push rod 82, slide bar 83, handle casing 84 and lock-screw 86.The distal seat 81 that connects straight-through haemostatic valve 70 is inserted in the hole of push rod 82 far-ends, and is fixedly connected by gluing method.Distal seat 81 is tubular.The near-end of push rod 82 inserts in the hole of handle casing 84 far-ends, along the hole formation sliding-contact of axis and handle casing 84 far-ends.
As shown in figure 16, handle casing 84 is constituted by right half part 84R and left-half 84L along the axis symmetry.Right half part 84R is connected by screw with left-half 84L or adopts the method for glueing joint to be connected to form handle casing 84 integral body.
As Figure 15 and shown in Figure 16, handle casing 84 is cylinder, have coaxial two-stage ladder hole vertically, the aperture in the hole of far-end is greater than the aperture in the hole of near-end, extended upward projection 841 in distal end column outer rim, projection 841 inside are square square space for the cross section, square space top is that size is less than the square aperture of square space, along handle casing 84 axially, sawtooth is arranged at top in the square space of the both sides of square aperture, projection 841, be used for slide bar 83 on engagement.Wall at the square space near-end has hole 844.Gullet plate 836 and the spring leaf 85 of square space in order to slide bar 83 to be installed, the handle 834 of slide bar 83 stretches out from square aperture.Have first screw 842 on the cylinder of projection 841 near-ends one side, the near-end of the right half part of handle casing 84 has second screw 843.
As Figure 17 and shown in Figure 180, push rod 82 is made up of pusher body 821 and damped ring 822, and pusher body 821 central cylindrical outer rims have damped ring 822 along circumferentially embedding.
As Figure 19, Figure 20 and shown in Figure 21, pusher body 821 is cylindric, have coaxial two-stage ladder hole vertically, the aperture in the hole of far-end is greater than the aperture in the hole of near-end, the column outer rim is along circumferentially having a ring cross-section to be shaped as trapezoidal trapezoidal projection near push rod 82 distal ends, push rod 82 central cylindrical outer rims embed the groove of placing damped ring 822 along circumferentially having, pusher body 821 near-end column outer rim tops have length dimension along the elongated slot 823 of axis, after being used in the hole that near-end with push rod 82 inserts handle casing 84 far-ends, in first screw 842 of handle casing 84, screw in screw, this screw end extend in the elongated slot 823 of pusher body 821, the distance that restriction push rod 82 relative handle casings 84 slide.
As Figure 22, Figure 23, Figure 24 and shown in Figure 25, slide bar 83 tops are the handle 834 of short cylinder shape, and handle 834 connects tabular gullet plate 836 through the contiguous block 835 of cuboid shape, and gullet plate 836 tops have sawtooth 833.Have through hole 831 in the gullet plate 836 along its length, the axis normal of the axis of through hole 831 and handle 834 has the axis of the 3rd screw 832, the three screws 832 that are communicated with through hole 831 and the axis normal of through hole 831 on the top gullet plate 836 of through hole 831.
As shown in figure 26, the gullet plate 836 of slide bar 83 is packed in projection 841 the square space, the handle 834 of slide bar 83 stretches out from square aperture, between gullet plate 836 bottoms and the square space bottom tabular spring leaf 85 is housed, under the power that the upsprings effect of spring leaf 85, the sawtooth 833 on the gullet plate 836 and the engagement of the square space inner top of projection 841.
As Figure 27 and shown in Figure 28, spring leaf 85 is shaped as the tabular of circular arc.
In renal artery orbital radio frequency melting electrode catheter 200 structures of embodiment two, there is not the helical orbit seal wire delivery conduit 30 in embodiment one structure.When the doctor pushes helical orbit seal wire 60 by guiding catheter 20 to far-end, helical orbit seal wire 60 far-ends are by behind the catheter block 22 of guiding catheter 20, the near-end of taenidium 62 is passed the straight hole of Y type haemostatic valve 50 from far-end to near-end, raw silk rings 63 near-ends pass to another branched hole from the far-end of Y shape haemostatic valve 50, again Y shape haemostatic valve 50 is connected on the connection Cuo 22 of guiding catheter 20, push raw silk rings 63 and taenidium 62 to far-end, helical orbit seal wire 60 easily can be pushed in the renal artery blood vessel.
After the distal guide wire head spring 61 of helical orbit seal wire 60 is positioned at the branch vessel of renal artery blood vessel, operative doctor inserts the near-end of helical orbit seal wire 60 in the hole of radio-frequency (RF) ablation conduit 40 far-ends, pass seat 44, one near-end that holds helical orbit seal wire 60 keeps maintaining static, another hands pushes radio-frequency (RF) ablation conduit 40 to far-end, and radio-frequency (RF) ablation conduit 40 is along helical orbit seal wire 60, internal channel is advanced to far-end in the hole of guiding catheter 20.When the pushed spiral coil to helical orbit seal wire 60 of radio-frequency (RF) ablation conduit 40, because the far-end of radio-frequency (RF) ablation conduit 40 is very soft, continuation is during to propelling movement radio-frequency (RF) ablation conduit 40 far away, and the electrode retaining collar 47 of radio-frequency (RF) ablation conduit 40 far-ends will move as helical form to far-end along with the spiral coil of radio-frequency (RF) ablation conduit 40 along helical orbit seal wire 60.
The far-end of radio-frequency (RF) ablation conduit 40 is pushed to position near spiral coil along helical orbit seal wire 60, stop to push.The far-end that connects straight-through haemostatic valve 70 at the seat 44 of radio-frequency (RF) ablation conduit 40, and connect the distal seat 81 of upper handle combination 80 at the near-end of straight-through haemostatic valve 70, the near-end of the taenidium 62 of helical orbit seal wire 60 is passed from the ladder hole of the ladder hole of pusher body 821 and handle casing 84 through straight-through haemostatic valve 70, distal seat 81, through second screw, 843 set and locking screw silks 62 and handle housing 84, the near-end of taenidium 62 is fixed on the handle housing 84 with screw 86.The near-end of the raw silk rings 63 of the helical orbit seal wire 60 straight hole far-end from Y type haemostatic valve 50 is inserted, stretch out from inclined hole, hole 844 on projection 841 square space proximal end wall again, insertion is positioned at the through hole 831 of the slide bar 83 of projection 841 square space, screws in the 3rd screw 832 interior near-ends with raw silk rings 63 with a screw and is fixed on the slide bar 83.
During operation, the doctor with thumb downwards by and draw the handle 834 of slide bar 83 to near-end, raw silk rings 63 is strained to near-end.After unclamping thumb, the elastic force of spring leaf 85 is with slide bar 83 jack-up upwards, and the sawtooth 833 on the gullet plate 836 of slide bar 83 and the engagement of the square space inner top of projection 841 make raw silk rings 63 keep tensions, produce tightening force.
Because the near-end of taenidium 62 is fixed on the handle housing 84, helical orbit seal wire 60 far-ends are subjected to raw silk rings 63 to the pulling force of near-end, and the spiral coil of taenidium 62 is shortened to near-end, so the increase of the diameter of spiral coil, and the result is that spiral coil is close to the renal artery blood vessel wall.Can connect radiofrequency generator this moment with adapter, and the discharge of startup radiofrequency generator is melted.
When any sympathetic nerve of renal artery vessel outer wall melted finish after, the doctor holds handle combination 80, down by and promote slide bar 83 to far-end, raw silk rings 63 is pushed into relaxed state, taenidium 62 reinstatement under the elastic force effect of self, reduced.Promote push rod 82 to far-end radio-frequency (RF) ablation conduit 40 is advanced certain distance to far-end.Because the damped ring 822 on the push rod 82 and the effect of the frictional force between the handle housing 84 are unclamped finger rear push-rod 82 and are kept transfixion.
Repeat above process, electrode retaining collar 47 is moved along the spiral coil of helical orbit seal wire 60, therefore, the electrode retaining collar 47 that the doctor can control radio-frequency (RF) ablation conduit 40 melts at the diverse location of spiral coil.
The spiral coil of the helical orbit seal wire 60 among the embodiment two is slightly less than the diameter (internal diameter) of renal artery blood vessel, can by control crank make up 80 slide bar 83 to near-end pulling raw silk rings 63 certain distances, shorten the helical spring pitch of helical orbit seal wire 60, the diameter that spiral coil is increased to the renal artery blood vessel melts; Be returned to diameter less than the renal artery blood vessel and promote slide bar 83 rear screw circles to far-end.So both can guarantee to effectively the melting of renal artery blood vessel the inwall of injured blood vessel not in the time of to guarantee to promote ablating electrode conduit 40 forward again.
Finish after the melting of having a few, all screws on doctor's release handle housing, and with handle combination 80 and straight-through haemostatic valve 70 disengagements, take off handle combination 80, take off straight haemostatic valve 70 simultaneously, extract radio-frequency (RF) ablation conduit 40 out the person of undergoing surgery external along helical orbit seal wire 60 to near-end, draw the taenidium 62 of helical orbit seal wire 60 to near-end, helical orbit seal wire 60 is drawn within the guiding catheter 20, helical orbit seal wire 60 and guiding catheter 20 are taken out the external radiofrequency ablation therapy operation process of finishing along near-end in the lump.
Zoopery
One, laboratory animal: select 2 of experiment pig, first pig body weight 45Kg, second pig body weight 55Kg.
Two, experimental technique:
1, art is preceding prepares: Animal Anesthesia: 4% pentobarbital sodium solution, and press the 1ml/kg body weight and calculate elder generation to 2/3 dosage, after disappearing, the eyelash reflex of observation animal begins experiment, inject 2ml/ time more in case of necessity in the operation process.
2, operating procedure: isolate the right femoral artery of pig, cut right inguinal skin and the muscular tissue of pig, find the right femoral artery of pig, the tendon around cutting with scalpel, separately right femoral artery is moved and right femoral vein, row femoral artery puncture art.Insert the puncture sheath, the superslide seal wire is directed in the aorta of pig.5F radiography pipe is inserted into along the superslide seal wire in the aorta of pig, injects the capable DSA Digital Subtraction of contrast agent technology and finds renal artery bilateral approach.
3, adopt the renal artery orbital radio frequency melting electrode catheter of embodiment one structure, carry out the right side renal artery radio-frequency (RF) ablation of pig.Adopt the renal artery orbital radio frequency melting electrode catheter of embodiment one structure, carry out the left side renal artery radio-frequency (RF) ablation of pig, X-ray photograph shows, be positioned at the right renal artery blood vessel of pig when the radio-frequency (RF) ablation conduit after, operator one holds that the helical orbit seal wire maintains static, another holds the radio-frequency (RF) ablation conduit and advance to far-end, the far-end of radio-frequency (RF) ablation conduit can along the helical orbit seal wire in the shape of a spiral shape advance.See that under X-ray remote electrode whenever advances behind the certain distance, suspend to advance, start radiofrequency generator and discharge and melt that push ahead certain distance when any melts again after finishing, reignition is melted.Every side renal artery along helical orbit carry out 3-6 point position melt finish after, the helical orbit seal wire is placed in the opposite side renal artery, melt by the discharge of above step.
Adopt the renal artery orbital radio frequency melting electrode catheter of embodiment one structure, carry out second of left renal artery and melt, the actual ablation parameters in the time of the 17th second, power 9W, 54 ℃ of temperature, impedance 142 Ω.
If adopt the renal artery orbital radio frequency melting electrode catheter of embodiment two structures, carrying out renal artery melts, at first guiding catheter is inserted in the left side or right renal artery of pig, after the raw silk rings that pinches the helical orbit seal wire inserts the remote spring conductive filament head of helical orbit seal wire in the hole of seat 22 of guiding catheter, continuation pushes the raw silk rings of helical orbit seal wire to far-end, and the far-end spiral coil that makes the helical orbit seal wire enters in the left side or right renal artery blood vessel of pig by the passage of guiding catheter.Because the taenidium of helical orbit seal wire is to be made by nickel-titanium shape memory alloy material, spiral coil namely reverts to helical form after in a single day being pushed out guiding catheter.This moment, the seat at guiding catheter connected Y shape haemostatic valve, and the taenidium of helical orbit seal wire passes from the straight hole of Y shape haemostatic valve, and the raw silk rings of helical orbit seal wire passes from the inclined hole of Y shape haemostatic valve.The near-end of the taenidium of helical orbit seal wire is inserted in the hole of far-end of radio-frequency (RF) ablation conduit, pinch taenidium on the other hand, advance the radio-frequency (RF) ablation conduit to the spiral coil of helical orbit seal wire to far-end on the other hand.Seat at the radio-frequency (RF) ablation conduit connects straight haemostatic valve then, connects control crank in straight haemostatic valve.The near-end of taenidium is screwed in the stepped bore on the control crank; The near-end of raw silk rings is fixed in the through hole of slide bar.Hold handle, stir slide bar tension raw silk rings to near-end, the diameter of the spiral coil of helical orbit seal wire produces slight the increase in the pulling force effect of raw silk rings, thereby spiral coil is adjacent to the renal artery blood vessel wall.Connecting the radiofrequency generator discharge melts.When certain a bit melted by discharge finish after, stir slide bar to far-end, make the raw silk rings of helical orbit seal wire loose, slight dwindling will take place in the diameter of the spiral coil of helical orbit seal wire, thereby do not take place closely to contact with the renal artery blood vessel wall, push the radio-frequency (RF) ablation conduit to far-end and move, alleviate the far-end of radio-frequency (RF) ablation conduit along spiral coil to the damage of renal artery blood vessel generation.When advancing radio-frequency (RF) ablation conduit certain distance to far-end, repeat above-mentioned tension, discharge, unclamp action, can produce multiple spot to the renal artery blood vessel and melt.
4, post surgery treatment: femoral artery is pressed hemostasis, point of puncture pressure dressing, intramuscular injection penicillin sodium 800,000 unit prevention infection.
5, aneurysmal histopathologic examination: gross anatomy: operation is put to death experiment pig after January, pathological tissue light, electron microscopic examination are observed the orthosympathetic situation that interrupts of kidney, the nerve of outer wall that discovery is attached to the left and right renal artery blood vessel of the pig that is implemented experiment all is opened, and obvious impairment does not take place the inner membrance of renal artery blood vessel.
Description of test: renal artery orbital radio frequency melting electrode catheter of the present utility model can produce good ablation effect to the renal artery blood vessel.Can interrupt the sympathetic nerve that is attached to the renal artery vessel outer wall wholly or in part according to doctor's therapeutic scheme, carry out renal artery with renal artery orbital radio frequency melting electrode catheter of the present utility model and melt, can reach the purpose for the treatment of intractable hypertension.
Claims (10)
1. renal artery orbital radio frequency melting electrode catheter, it is characterized in that: described renal artery orbital radio frequency melting electrode catheter is provided with helical orbit seal wire and radio-frequency (RF) ablation conduit (40), the helical orbit wire distal is one section helical form, and radio-frequency (RF) ablation conduit (40) slides along the helix of helical orbit seal wire.
2. renal artery orbital radio frequency melting electrode catheter according to claim 1, it is characterized in that: described radio-frequency (RF) ablation conduit (40) far-end has electrode retaining collar (47), and electrode retaining collar (47) slides along the helix of helical orbit seal wire.
3. renal artery orbital radio frequency melting electrode catheter according to claim 1 and 2, it is characterized in that: described radio-frequency (RF) ablation conduit (40) is provided with catheter body (41), the far-end outer rim of catheter body (41) embeds the electrode retaining collar (47) that annular is arranged, the near-end of catheter body (41) passes contiguous block (42), is connected with the far-end of seat (44).
4. renal artery orbital radio frequency melting electrode catheter according to claim 3, it is characterized in that: described catheter body (41) is provided with coaxial pipe (411), internal diameter 0.46mm, coaxial pipe (411) outer from far-end to near-end, order is equipped with soft tip (416), electrode retaining collar (47), first section sleeve pipe (413), second section sleeve pipe (414), the 3rd section sleeve pipe (415); Described soft tip (416) is taper, long 10mm, and maximum outside diameter is 1.50-1.60mm, selects flexible plastic PU80AE pipe or metal coil spring for use; Described electrode retaining collar (412) is platinumiridio or platinum ring, long 1-3mm, external diameter 1.52mm, internal diameter 1.40mm; The hardness of described first section sleeve pipe (413), second section sleeve pipe (414), the 3rd section sleeve pipe (415) is from distal-to-proximal hardening gradually, and its material is polyurethane, nylon elastomer, high density polyethylene (HDPE) or nylon.
5. renal artery orbital radio frequency melting electrode catheter according to claim 4 is characterized in that: the plastic layer (4111) that described coaxial pipe (411) is made of polyurethane, nylon elastomer or nylon, the metal spring (4112) and the metallic steel silk screen (4113) that embed are wherein formed; One section 30mm length range of described plastic layer (4111) distal end external diameter 0.61mm, the remainder external diameter is 0.66mm; Described metal spring (4112) adopts the stainless steel silk of diameter 0.025mm, turns to external diameter 0.48mm, pitch 0.076-0.127mm, and length is 1200 helical spring; It is the stainless steel silk of 0.0127mm * 0.038mm that described metallic steel silk screen (4113) adopts the cross section, is woven into density for contain the steel wire in 55-120 cross point along coaxial pipe (411) axis per inch length.
6. renal artery orbital radio frequency melting electrode catheter according to claim 5, it is characterized in that: described helical orbit seal wire (10) is provided with wire guide axle (12), wire guide axle (12) adopts the niti-shaped memorial alloy silk of diameter 0.36-0.46mm, 30-50mm turns to coil spring shape at the distance distal end, its external diameter is 4-6mm, pitch 15-20mm, length is 30-40mm.
7. renal artery orbital radio frequency melting electrode catheter according to claim 6, it is characterized in that: described wire guide axle (12) far-end is nested with and is connected with spring-guide wire head (11), spring-guide wire head (11) adopts stainless steel silk or the platinum wire of diameter 0.1mm, turn to external diameter 0.36mm, pitch 0.1-0.127mm, length is the coil spring shape of 20-40mm.
8. renal artery orbital radio frequency melting electrode catheter according to claim 5, it is characterized in that: described helical orbit seal wire (60) is provided with taenidium (62) and raw silk rings (63); Described taenidium (62) adopts the niti-shaped memorial alloy silk of diameter 0.36-0.41mm, turn to coil spring shape at distance distal end 30-50mm place, helical spring external diameter is slightly less than the diameter of renal artery blood vessel, and pitch is 15-20mm, and long is 30-40mm; Described raw silk rings (63) adopts the stainless steel silk of diameter 0.41-0.46mm; Described raw silk rings (63) is set up in parallel with taenidium (62), and at one section of coil spring shape and its axis coaxle, far-end is welded to connect.
9. renal artery orbital radio frequency melting electrode catheter according to claim 8, it is characterized in that: the far-end of described taenidium (62) and raw silk rings (63) is nested with and is connected with conductive filament head spring (61), conductive filament head spring (61) adopts stainless steel silk or the platinum wire of diameter 0.1mm, turn to external diameter 0.36mm, pitch 0.1-0.127mm, length is the coil spring shape of 20-40mm.
10. renal artery orbital radio frequency melting electrode catheter according to claim 9, it is characterized in that: the near-end of described seat (44) connects handle combination (80) through straight-through haemostatic valve (70), the near-end of described raw silk rings (63) is connected in the handle combination (80), and handle combination (80) is provided with control to the mechanism of the stretching silk of near-end (63).
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| Application Number | Priority Date | Filing Date | Title |
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| CN 201220289499 CN203059897U (en) | 2012-06-19 | 2012-06-19 | Renal artery orbit radio frequency ablation electrode catheter |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220289499 CN203059897U (en) | 2012-06-19 | 2012-06-19 | Renal artery orbit radio frequency ablation electrode catheter |
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| CN203059897U true CN203059897U (en) | 2013-07-17 |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102772249A (en) * | 2012-06-19 | 2012-11-14 | 深圳市惠泰医疗器械有限公司 | Radiofrequency ablation electrode catheter of renal artery rail |
| CN105326562A (en) * | 2014-06-24 | 2016-02-17 | 上海安通医疗科技有限公司 | Catheter device for regulating renal nerves |
| CN106362291A (en) * | 2015-08-21 | 2017-02-01 | 贾玉和 | Dual-purpose catheter used for intracardial mapping and defibrillation |
| CN110074861A (en) * | 2018-09-14 | 2019-08-02 | 杭州堃博生物科技有限公司 | Radio frequency ablation catheter, lung's radio frequency ablation system and corresponding control method, control device and computer readable storage medium |
| CN113384319A (en) * | 2021-06-02 | 2021-09-14 | 上海腾复医疗科技有限公司 | A catheter |
| CN110074861B (en) * | 2018-09-14 | 2024-05-07 | 杭州堃博生物科技有限公司 | Radiofrequency ablation catheter, pulmonary radiofrequency ablation system, and corresponding control method, control device and computer-readable storage medium |
-
2012
- 2012-06-19 CN CN 201220289499 patent/CN203059897U/en not_active Expired - Lifetime
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102772249A (en) * | 2012-06-19 | 2012-11-14 | 深圳市惠泰医疗器械有限公司 | Radiofrequency ablation electrode catheter of renal artery rail |
| CN102772249B (en) * | 2012-06-19 | 2015-01-21 | 深圳市惠泰医疗器械有限公司 | Radiofrequency ablation electrode catheter of renal artery rail |
| CN105326562A (en) * | 2014-06-24 | 2016-02-17 | 上海安通医疗科技有限公司 | Catheter device for regulating renal nerves |
| CN106362291A (en) * | 2015-08-21 | 2017-02-01 | 贾玉和 | Dual-purpose catheter used for intracardial mapping and defibrillation |
| CN110074861A (en) * | 2018-09-14 | 2019-08-02 | 杭州堃博生物科技有限公司 | Radio frequency ablation catheter, lung's radio frequency ablation system and corresponding control method, control device and computer readable storage medium |
| CN110074861B (en) * | 2018-09-14 | 2024-05-07 | 杭州堃博生物科技有限公司 | Radiofrequency ablation catheter, pulmonary radiofrequency ablation system, and corresponding control method, control device and computer-readable storage medium |
| CN113384319A (en) * | 2021-06-02 | 2021-09-14 | 上海腾复医疗科技有限公司 | A catheter |
| CN113384319B (en) * | 2021-06-02 | 2023-04-25 | 上海腾复医疗科技有限公司 | Catheter |
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Address after: 518057 601, building B, Tongfang information port, No. 11, songpingshan Langshan Road, songpingshan community, Xili street, Nanshan District, Shenzhen City, Guangdong Province Patentee after: Shenzhen huitai Medical Equipment Co., Ltd Address before: The comprehensive building of Tsinghua Nanshan District Keyuan Road Shenzhen city Guangdong province 518057 room 804 Patentee before: Shenzhen Huitai Medical Instrument Co., Ltd. |
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Granted publication date: 20130717 |