CN203033140U - Leakage-proof reagent bottle capable of rapidly detecting acquired immune deficiency syndrome through spittle - Google Patents
Leakage-proof reagent bottle capable of rapidly detecting acquired immune deficiency syndrome through spittle Download PDFInfo
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- CN203033140U CN203033140U CN 201320036090 CN201320036090U CN203033140U CN 203033140 U CN203033140 U CN 203033140U CN 201320036090 CN201320036090 CN 201320036090 CN 201320036090 U CN201320036090 U CN 201320036090U CN 203033140 U CN203033140 U CN 203033140U
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- dropping liquid
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Abstract
A leakage-proof reagent bottle capable of rapidly detecting acquired immune deficiency syndrome through spittle comprises an upper end cover, a bottle body, a filter net, a lower end cover and an elastic sealing ring, wherein the upper end cover is connected on an outer thread of an upper cover of the bottle body in a screwed mode, a sealing taper sleeve of the upper end cover is matched with a taper hole of a bottle opening of the bottle body in a seal mode, and the elastic sealing ring is arranged between the upper end cover and the upper end face of the bottle opening of the bottle body. Due to the fact that the elastic sealing ring is additionally arranged between the upper end cover and the upper end face of the bottle opening of the bottle body, the sealing taper sleeve is arranged in the upper end cover, the bottle opening taper hole is formed at the upper end of the bottle opening of the bottle body, and the sealing taper sleeve is matched with an inner hole of a taper face in a sealing mode. When the upper end cover is tightly screwed on the bottle opening, the upper end cover and the bottle opening form a three-section sealing structure, a first-section sealing structure is a taper sealing structure between the sealing taper sleeve of the upper end cover and the taper hole of the bottle opening of the bottle body, a second-section sealing structure is the elastic sealing ring between the upper end cover and the upper face of the bottle opening of the bottle body, and a third-section sealing structure is a thread sealing structure between the upper end cover and the bottle opening, so that the leakage defect of the reagent bottle can be completely eradiated.
Description
Technical field:
The utility model relates to a kind of articles for use of fast detecting acquired immune deficiency syndrome (AIDS), relates in particular to a kind of be used to the reagent bottle of depositing the fast detecting acquired immune deficiency syndrome (AIDS).
Background technology:
HIV is that the medical science of acquired immune deficiency syndrome (AIDS) is called for short, be aids, being human, (Human Immunodeficiency Virus causes immunodeficiency after HIV) because infect human immunodeficiency virus, concurrent a series of opportunistic infections and tumour, severe patient can cause dead syndrome.Still there is not effective cure method at present.Since 1981 diagnosed out the first AIDS patient, acquired immune deficiency syndrome (AIDS) is rapid spread in the world, had become the public health problem of serious threat people of the world health.
Though the now existing multiple method of inspection of acquired immune deficiency syndrome (AIDS), these methods need expensive analytical equipment and instrument mostly, need healthcare givers and the professional skill of specialty, and test sample mostly are blood.This has determined these methods can only be confined to the laboratory and medical institutions use, and can not be used by ruck.This has also caused aids prevention to rely on " passive prevention " present situation of medical institutions.
Show that according to the study also contain HIV antibody in the saliva, saliva can replace blood to detect sample as acquired immune deficiency syndrome (AIDS).But because the HIV AC has only 1/100 in the blood in the saliva, and has many not clear interfering materials, utilize the saliva sample diagnosis of aids just to need more highly sensitive detection reagent, otherwise many false negative result will occur.This is one and has a challenging difficult problem.
The applicant passes through years of researches, set about from core material, select the dynamical HIV antigen of high purity for use, utilize the processing buffer system of the uniqueness of oneself developing, make antigen after mark and immobilization processing, still keep High Performance, and greatly reduce in the saliva interference effect of not clear material, guaranteeing the specific while, detection sensitivity has been brought up to 1/100 of haemoconcentration, 000, " not having wound domestic type acquired immune deficiency syndrome (AIDS) testing product "---human immune defect virus antibody (HIV1/2) oral secretion detection kit (colloidal gold method) that successfully having developed can be employed by ruck, and obtain " the medicine equipment registration certificate " that State Food and Drug Administration issues.
Compare with acquired immune deficiency syndrome (AIDS) method of inspection in the past, applicant's exploitation " not having wound domestic type acquired immune deficiency syndrome (AIDS) testing product " has following characteristics:
1. safety does not have wound: need not take a blood sample, avoid the risk of cross-infection and occupational exposure, but the acceptance height.
2. easy and simple to handle: need not training and professional skill, need not accessory equipment, naked eyes read to declare the result.
3. privacy protection: use not limited by time and space, singlely can finish detection.
4. detection speed is fast: can show the result in 10-20 minute
5. the highly sensitive high specificity of product: taken the lead by Chinese CDC principal expert professor Shao Yiming, be reference reagent with AIDS blood examination product, the applicant has carried out the clinical trial of this product in Microbiology and Epidemic Disease Inst., Academy of Military-Medical Sciences (C, disease prevention and control center, Sichuan Province, three tame medical institutions of Jiangsu Prov. Disease Preventing and Controlling Center.Clinical effectiveness shows that positive coincidence rate is 98.28%, and negative match-rate is 99.87%, and total coincidence rate is 99.20%.
" not having wound domestic type acquired immune deficiency syndrome (AIDS) testing product " of applicant's invention changed " passive prevention " present situation of aids prevention dependence professional medical mechanism, and everybody can both be participated, and really realizes " whole people's participation " of aids prevention.Thereby can more effectively prevent spreading of AIDS, have far-reaching social effect.
Be " not the having wound domestic type acquired immune deficiency syndrome (AIDS) testing product " that discloses applicant's invention in 201120570444.0 in the patent No., it is a kind of complete detection utensil by people's body fluid fast detecting acquired immune deficiency syndrome (AIDS), it comprises acquisition rod, reagent bottle and testing cassete, wherein acquisition rod is used for gathering the secrete that is attached on the tooth from people's oral cavity, depositing test fluid in the reagent bottle, testing cassete is used for reaction and the demonstration of oral secretion and test fluid, after acquisition rod is gathered sample, directly be put in the reagent bottle, and acquisition rod fractureed from the indentation, there that fractures, the sampling end of acquisition rod is stayed in the reagent bottle, owing in the reagent bottle conditioning fluid is housed, the sample that collects on the sampling end enters in the conditioning fluid by overturning to rock repeatedly, the bottom end cover of reagent bottle as long as outward winding, make the dropping liquid mouth of reagent bottle lower end aim at liquid collecting hole on the testing cassete, splash into several liquid to be checked by the manual squeezing mode to liquid collecting hole, wait for 10 ~ 20 minutes, the color change situation of the test strips in the inspection door can judge whether the detected person is the HIV-positive.Acquisition rod directly is put in the reagent bottle after sample collection in whole testing process, do not pollute the environment, conditioning fluid is contained in the reagent bottle, the pollution of can not outflowing, test strip is placed between the box body and lid of testing cassete, all detect utensil and do not pollute other people, and sample can be kept in the reagent bottle and seal up for safekeeping simultaneously.
In actual production and use, the applicant finds that also there is a certain proportion of phenomenon of leakage in reagent bottle, through observing repeatedly and analyzing, upper end cover and the design of Sealing Structure between the bottle of finding reagent bottle are unreasonable, though be provided with the cone hermetically-sealed construction between the two, but in the actual production process, the bottleneck taper hole of bottleneck is all by injection-compression molding on the outer gland sealing tapered sleeve that is provided with in the endoporus of upper end cover and the bottle, working accuracy is not high, even Mould Machining reaches designing requirement, but also there is influence in other technological factor of actual pressure injection to the quality of product, therefore, after the loam cake external thread rotary of the last bottleneck cylindrical of upper end cover and bottle connects, be difficult to guarantee formation failure-free hermetically-sealed construction between the last bottleneck of upper end cover and bottle, this is the major cause that causes the reagent bottle leakage, therefore must improve it.
The utility model content:
The purpose of this utility model provides a kind of leakproof reagent bottle by saliva fast detecting acquired immune deficiency syndrome (AIDS).
The technical solution of the utility model is as follows:
A kind of leakproof reagent bottle by saliva fast detecting acquired immune deficiency syndrome (AIDS) comprises upper end cover, bottle, filter screen and bottom end cover, and described upper end cover comprises negative thread, sealing tapered sleeve and inner top surface, and the sealing tapered sleeve is arranged on the center of negative thread, and is connected as a single entity with inner top surface; Described bottle is made up of bottleneck upper surface, loam cake outside thread, upper limit step, lower cover outside thread, dropping liquid mouth, dropping liquid micropore, clean sap cavity and mixed chamber, the loam cake outside thread is arranged on the bottleneck cylindrical, the lower cover outside thread is arranged on the lower end cylindrical of bottle, the dropping liquid mouth is arranged on the lower surface of bottle, the dropping liquid micropore is arranged on the center of dropping liquid mouth, the epimere diameter of described dropping liquid micropore is 0.3 ~ 0.6 millimeter, hypomere is taper hole, up-small and down-big, maximum gauge is 1 ~ 3 millimeter, and clean sap cavity is positioned at the below in mixed chamber; Upper end cover is screwed in by negative thread on the loam cake outside thread of bottle, and the sealing tapered sleeve on the upper end cover and the bottleneck taper hole of bottle are sealed and matched, and are provided with elastic seal ring between the bottleneck upper surface of the inner top surface on the upper end cover and bottle; Filter screen is arranged on the bottom of bottle intracavity, and between clean sap cavity and mixed chamber, filter screen is positioned at the top of dropping liquid micropore, bottom end cover is screwed on the lower cover outside thread of bottle, be provided with the sealing frustum in the endoporus of bottom end cover, the taper hole of the dropping liquid micropore lower end on sealing frustum and the dropping liquid mouth is sealed and matched.
Owing between the bottleneck upper surface of upper end cover and bottle, set up elastic seal ring, in upper end cover, be provided with the sealing tapered sleeve, bottleneck upper end at bottle is provided with the bottleneck taper hole, sealing tapered sleeve and bottleneck taper hole are sealed and matched, like this, after upper end cover is tightened on the bottle, between upper end cover and bottle, just form three seal structures, first road is conical surface seal structure between the sealing tapered sleeve of upper end cover and the bottleneck taper hole on the bottle, second road is the elastic seal ring that is arranged between the bottleneck upper surface of the inner top surface of upper end cover and bottle, the 3rd road is thread seal structure between upper end cover and the bottle, can effectively stop the defective that reagent bottle leaks.
Using method of the present utility model is as follows:
The first step, reagent are prepared: the upper end cover of outwarding winding, the sample treatment solution of specified quantitative is poured in the bottle, and screw upper end cover;
Second step, sample collection: the detected person slightly gargles with warm boiling water earlier, take out acquisition rod after spending 10 minutes, the sampling end is stretched in detected person's the oral cavity, the side edge inboard wiping gently of gums down with the sampling end, one jiao from mouth begins slowly to wipe another angle, and then with the another side of sampling end along the inboard of last gums gently wiping return;
The 3rd step, sample process: the upper end cover of outwarding winding, will the sampling end insertion reagent bottle through the acquisition rod of sample collection in, fracture from the indentation, there that fractures by hand holding handle then, sampling end is stayed in the bottle, screwed upper end cover, hand-held reagent bottle overturns repeatedly and rocks 25 ~ 30 times and get final product;
The 4th step, pattern detection: get testing cassete and keep flat on the table, the outward winding bottom end cover of reagent bottle, make the dropping liquid mouth of reagent bottle lower end aim at liquid collecting hole on the testing cassete, splash into 2 ~ 3 liquid to be checked by the manual squeezing mode to liquid collecting hole, wait for 20 ~ 30 seconds, observe the color of the test strips under it from inspection door, the reference standard bar can be judged.
Description of drawings:
Fig. 1 is structural representation of the present utility model;
Fig. 2 is the decomposition texture scheme drawing of Fig. 1;
Wherein: the 1-upper end cover; The 2-bottle; The 3-filter screen; The 4-bottom end cover; The 5-elastic seal ring; The 11-negative thread; 12-seals tapered sleeve; The 13-inner top surface; 21-bottleneck upper surface; 22-loam cake outside thread; 23-upper limit step; 24-lower cover outside thread; 25-dropping liquid mouth; 26-dropping liquid micropore; The clean sap cavity of 27-; 28-mixes the chamber; 41-seals frustum.
The specific embodiment:
Describe specific embodiments of the present utility model in detail below in conjunction with accompanying drawing:
A kind of leakproof reagent bottle by saliva fast detecting acquired immune deficiency syndrome (AIDS), comprise upper end cover 1, bottle 2, filter screen 3 and bottom end cover 4, described upper end cover 1 comprises negative thread 11, sealing tapered sleeve 12 and inner top surface 13, and sealing tapered sleeve 12 is arranged on the center of negative thread 11, and is connected as a single entity with inner top surface 13; Described bottle 2 is by bottleneck upper surface 21, loam cake outside thread 22, upper limit step 23, lower cover outside thread 24, dropping liquid mouth 25, dropping liquid micropore 26, clean sap cavity 27 and mixed chamber 28 are formed, loam cake outside thread 22 is arranged on the bottleneck cylindrical, lower cover outside thread 24 is arranged on the lower end cylindrical of bottle, dropping liquid mouth 25 is arranged on the lower surface of bottle, dropping liquid micropore 26 is arranged on the center of dropping liquid mouth 25, the epimere diameter of described dropping liquid micropore 26 is 0.3 ~ 0.6 millimeter, hypomere is taper hole, up-small and down-big, maximum gauge is 1 ~ 3 millimeter, and clean sap cavity 27 is positioned at the below in mixed chamber 28; Upper end cover 1 is screwed in by negative thread 11 on the loam cake outside thread 22 of bottle 2, and the sealing tapered sleeve 12 on the upper end cover 1 is sealed and matched with the bottleneck taper hole of bottle 2, is provided with elastic seal ring 5 between the bottleneck upper surface 21 of the inner top surface 13 on the upper end cover 1 and bottle 2; Filter screen 3 is arranged on the bottom of bottle intracavity, and between clean sap cavity 27 and mixed chamber 28, filter screen 3 is positioned at the top of dropping liquid micropore 26, bottom end cover 4 is screwed on the lower cover outside thread 24 of bottle 2, be provided with sealing frustum 41 in the endoporus of bottom end cover 4, the taper hole of dropping liquid micropore 26 lower ends on sealing frustum 41 and the dropping liquid mouth 25 is sealed and matched.
Claims (1)
1. leakproof reagent bottle by saliva fast detecting acquired immune deficiency syndrome (AIDS), it is characterized in that: comprise upper end cover (1), bottle (2), filter screen (3) and bottom end cover (4), described upper end cover (1) comprises negative thread (11), sealing tapered sleeve (12) and inner top surface (13), sealing tapered sleeve (12) is arranged on the center of negative thread (11), and is connected as a single entity with inner top surface (13); Described bottle (2) is by bottleneck upper surface (21), loam cake outside thread (22), upper limit step (23), lower cover outside thread (24), dropping liquid mouth (25), dropping liquid micropore (26), clean sap cavity (27) and mixed chamber (28) are formed, loam cake outside thread (22) is arranged on the bottleneck cylindrical, lower cover outside thread (24) is arranged on the lower end cylindrical of bottle, dropping liquid mouth (25) is arranged on the lower surface of bottle, dropping liquid micropore (26) is arranged on the center of dropping liquid mouth (25), the epimere diameter of described dropping liquid micropore (26) is 0.3 ~ 0.6 millimeter, hypomere is taper hole, up-small and down-big, maximum gauge is 1 ~ 3 millimeter, and clean sap cavity (27) is positioned at the below of mixed chamber (28); Upper end cover (1) is screwed on the loam cake outside thread (22) of bottle (2) by negative thread (11), sealing tapered sleeve (12) on the upper end cover (1) cooperates with the bottleneck taper hole of bottle (2), is provided with elastic seal ring (5) between the bottleneck upper surface (21) of the inner top surface (13) on the upper end cover (1) and bottle (2); Filter screen (3) is arranged on the bottom of bottle intracavity, and be positioned between clean sap cavity (27) and mixed chamber (28), filter screen (3) is positioned at the top of dropping liquid micropore (26), bottom end cover (4) is screwed on the lower cover outside thread (24) of bottle (2), be provided with sealing frustum (41) in the endoporus of bottom end cover (4), the taper hole of dropping liquid micropore (26) lower end on sealing frustum (41) and the dropping liquid mouth (25) is sealed and matched.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320036090 CN203033140U (en) | 2013-01-23 | 2013-01-23 | Leakage-proof reagent bottle capable of rapidly detecting acquired immune deficiency syndrome through spittle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320036090 CN203033140U (en) | 2013-01-23 | 2013-01-23 | Leakage-proof reagent bottle capable of rapidly detecting acquired immune deficiency syndrome through spittle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203033140U true CN203033140U (en) | 2013-07-03 |
Family
ID=48685279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201320036090 Expired - Lifetime CN203033140U (en) | 2013-01-23 | 2013-01-23 | Leakage-proof reagent bottle capable of rapidly detecting acquired immune deficiency syndrome through spittle |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203033140U (en) |
-
2013
- 2013-01-23 CN CN 201320036090 patent/CN203033140U/en not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20130703 |