CN202960511U - Light sensing system - Google Patents
Light sensing system Download PDFInfo
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- CN202960511U CN202960511U CN 201220642726 CN201220642726U CN202960511U CN 202960511 U CN202960511 U CN 202960511U CN 201220642726 CN201220642726 CN 201220642726 CN 201220642726 U CN201220642726 U CN 201220642726U CN 202960511 U CN202960511 U CN 202960511U
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Abstract
The utility model discloses a light sensing system which is used for solving the technical problem of a low resolution of an existing conventional magnetic resonance scanner. The technical scheme includes that the light sensing system comprises a transmitting part and a receiving part, wherein the transmitting part consists of a pulse power supply, an infrared laser diode, a fiber-optic coupling transfer device and a laser transmitting optical fiber (3), the receiving part consists of an optical fiber receiving end, a signal transmitting optical fiber (4), an infrared detector, a pre-amplifier circuit, a data acquisition device and a data processing system, the laser transmitting optical fiber (3) corresponds to the signal transmitting optical fiber (4), the laser transmitting optical fiber (3) and the signal transmitting optical fiber (4) are alternately arranged on a line concentration gasket (2) to constitute a visual-center light sensor component Za and a motor center light sensor component Zb. Due to the fact that a light-velocity propagation device is adopted, a time resolution during the detection is improved.
Description
Technical field
This utility model relates to sensor field, particularly relates to a kind of optical sensor system.
Background technology
The mankind and a part of animal class, it is dynamic that cerebral tissue is blood oxygen when neural activity, and the Brain Tissues Image that utilizes mr imaging technique (MRI) to obtain in blood oxygen dynamic process is called functional mri (fMRI) technology.Blood flow changes and blood oxygen concentration to change general designation blood oxygen dynamic, when brain neurological motion, will increase the consumption of glucose and aerobic and anaerobic metabolism accordingly.Cerebral tissue response metabolic process namely increases the process of blood flow, and the delay of 1 to 5 second is arranged.Blood oxygen dynamic response to peaking, produced regional aerobic hemoglobin (oxyhemoglobin, HbO in the time of 4 to 5 seconds
2), deoxyhemoglobin (deoxyhemoglobin, HbR) concentration change, blood flow changes and blood volume-variation, i.e. blood oxygen coherent signal (Blood-oxygen-level dependence, BOLD).The ultimate principle of fMRI technology is exactly to utilize the magnetic strength rate of deoxyhemoglobin different and produce T1 or T2
*The gradation of image of weighting is poor.
Existing Magnetic Resonance Brain Tissues functional imaging exists many bottlenecks and unsolved difficult point, first, magnetic resonance imaging obtains a sub-picture or one section dynamic video data need the sufficiently long time (common more than 1 minute), fully covers k space or k-t space and just can reach required resolution; Yet blood oxygen of brain concentration change signal (Bold) is but instantaneous synchronous and dynamic two kinds of significant conditions.Therefore there are two defectives in it, and the first, the k spatial data of collection is non-from the same state of blood oxygen of brain concentration change signal (Bold), can't satisfy the requirement of temporal resolution.Second, at present the clinical and the most frequently used method of research fMRI is to use the Fast imaging pulse sequence such as planar pulse echo (EPI) to be reduced to the picture required time, its problem is, there is the remarkable shortcoming that anamorphose and spatial resolution are low, signal to noise ratio is low, and, temporal resolution low (greater than 1 second) still can't obtain the high time resolution image.
the clinical meaning of cerebral tissue function imaging is very important, because the Magnetic Resonance Brain Tissues functional imaging exists many bottlenecks and unsolved difficult point, the optical fault camera technique is used for cerebral function imaging and has received the research worker concern, " TASK-LESS OPTICAL MAPPING OF BRAIN FUNCTION USINGRESTING STATE FOUNCTIONAL CONNECTIVITY " (Joseph P.Culver et.al. that the United States Patent (USP) data base delivers, Appl.No.:12425743) having announced a kind of optical fault Detection Techniques surveys under resting state and without the Brain mapping picture under the task foment.Joseph points out what the conventional magnetic resonance functional imaging normally encouraged based on task, needs the hand exercise excitation as measuring motorium function of cortex state.This method temporal resolution is high, can reach human clinical's standard (millisecond yardstick), also can measure total hemoglobin (total hemoglobin, HbT), aerobic hemoglobin (oxyhemoglobin, HbO
2), deoxyhemoglobin (deoxyhemoglobin, HbR) concentration change and concentration absolute value etc.Yet, its shortcoming is that spatial resolution is low, in order to obtain Brain mapping picture more clearly, have and adopt nuclear magnetic resonance to unite the research that other detection method obtains higher resolution Brain mapping picture, as: magnetic resonance-brain electricity survey meter joint imaging (EEG-FMRI), the method is, use in conjunction brain electrical resistivity survey survey technology, brain electrical resistivity survey survey technology, temporal resolution higher (millisecond yardstick) provides the time dependent parameter correction for the fMRI process.Yet, this method does not have a kind of good synergistic mechanism, has many defectives: one, and the radio-frequency magnetic pulse meeting of MR scanner is at cerebral biological electricity exploring electrode induced current, rf pulse sequence is discrete time series, and brain electricity survey meter namely takes the corresponding time to turn-off measure by needs.They are two years old, the spatial variations gradient magnetic that MR scanner produces also can be at the electrode for encephalograms faradic current, and the gradient magnetic of this class sustainable existence is difficult to effectively eliminate the electric current that its induction produces, and there is the interference of sensor current signal in the signal that causes brain electricity survey meter to receive.Its three, head movement also can make the electrode for encephalograms faradic current produce noise under the effect in magnetic field.The 4th, the magnetic strength rate of electrode for encephalograms material can exert an influence to the inhomogeneities of magnetostatic field B0, and magnetic field bump can be brought scalloping, pseudo-shadow to magnetic resonance system.The heat effect that magnetic resonance-brain electricity survey meter joint imaging technology also exists electrode for encephalograms induced current to produce can be to the problem of skin burn.
Summary of the invention
In order to overcome the low deficiency of existing MR scanner resolution, this utility model provides a kind of optical sensor system.This system alternately is placed in Laser emission optical fiber and signal transmission fiber on the line concentration pad, forms visual centre optical sensor components Za and motorium optical sensor components Zb, owing to adopting the light velocity propagation device, can improve the temporal resolution in testing process.
The technical scheme that its technical problem that solves this utility model adopts is: a kind of optical sensor system is characterized in comprising radiating portion and receiving unit.Radiating portion is comprised of the pulse power, infra-red laser diode, coupling fiber carrying device and Laser emission optical fiber 3, and the pulse power, infra-red laser diode, coupling fiber carrying device and Laser emission optical fiber 3 are electrically connected to successively; Receiving unit is by optical fiber receiving terminal, signal transmission fiber 4, Infrared Detectors, front discharge road and data acquisition unit, data handling system form, optical fiber receiving terminal, signal transmission fiber 4, Infrared Detectors, front discharge road is electrically connected to successively with data acquisition unit, data handling system; Laser emission optical fiber 3 is corresponding with signal transmission fiber 4, the corresponding signal transmission fiber 4 of Laser emission optical fiber 3.Laser emission optical fiber 3 and signal transmission fiber 4 alternately are placed on line concentration pad 2, form visual centre optical sensor components Za and motorium optical sensor components Zb.
The material of described line concentration pad 2 is pyrolytic graphite foamed materialss.
Described visual centre optical sensor components Za is made of three twelve earthly branches Laser emission optical fiber 3 and three twelve earthly branches signal transmission fibers 4.
Described motorium optical sensor components Zb is made of 36 Laser emission optical fiber 3 and 36 supported signal Transmission Fibers 4.
Described Laser emission optical fiber 3 is hi bi birefringence fibers.
Described signal transmission fiber 4 is hi bi birefringence fibers.
The beneficial effects of the utility model are: Laser emission optical fiber and signal transmission fiber alternately are placed on the line concentration pad, form visual centre optical sensor components Za and motorium optical sensor components Zb, owing to adopting the light velocity propagation device, improved the temporal resolution in the testing process.
Below in conjunction with the specific embodiment, this utility model is elaborated.
Description of drawings
Fig. 1 is this utility model optical sensor system working position formula schematic diagram.
Fig. 2 is this utility model optical sensor system block diagram.
Fig. 3 adopts the visual centre optical sensor components Za of this utility model optical sensor system composition and the schematic diagram of motorium optical sensor components Zb.
Fig. 4 is this utility model optical sensor system algorithm block diagram.
Fig. 5 is axle location time division type functional mri method flow diagram when adopting this utility model optical sensor system optical method.
In figure, 1-nuclear magnetic resonance birdcage magnetic coil; 2-line concentration pad; 3-Laser emission optical fiber; The 4-signal transmission fiber.
The specific embodiment
With reference to Fig. 1~5, this utility model optical sensor system comprises radiating portion and receiving unit.Radiating portion is comprised of the pulse power, infra-red laser diode, coupling fiber carrying device and Laser emission optical fiber 3, and the pulse power, infra-red laser diode, coupling fiber carrying device and Laser emission optical fiber 3 are electrically connected to successively; Receiving unit is by optical fiber receiving terminal, signal transmission fiber 4, Infrared Detectors, front discharge road and data acquisition unit, data handling system form, optical fiber receiving terminal, signal transmission fiber 4, Infrared Detectors, front discharge road is electrically connected to successively with data acquisition unit, data handling system; Laser emission optical fiber 3 is corresponding with signal transmission fiber 4, the corresponding signal transmission fiber 4 of Laser emission optical fiber 3.Laser emission optical fiber 3 and signal transmission fiber 4 alternately are placed on line concentration pad 2, form visual centre optical sensor components Za and motorium optical sensor components Zb.
Based on the post-stimulatory cerebral tissue cortex of event blood oxygen dynamic response, measured the spatial distribution state set M of blood oxygen dynamic change by optical sensor system, the selected particular state M of the dynamic process of cortex response
ABe decision state.Be decision state M when detecting current state
AThe time, trigger magnetic resonance coil emission magnetic resonance signal driving pulse, gradient coding, data acquisition.When detecting the current state change, magnetic resonance device quits work.Repeat above-mentioned flow process to the k space or the k-t space data collection complete.
Laser emission optical fiber 3 and signal transmission fiber 4 alternately are placed on line concentration pad 2, and line concentration pad 2 is adjacent to detected person's head, and nuclear magnetic resonance birdcage magnetic coil 1 produces excitation radio-frequency pulse and receiving magnetic resonance signals.
Line concentration pad 2 adopts pyrolytic graphite (pyrolytic graphite) foamed materials, and this quality of materials is light and soft, and magnetic susceptibility and tissue are close, can reduce B
0The impact of magnetic field bump.
Laser emission optical fiber 3, signal transmission fiber 4 adopt high birefringence rate (high-birefringence) optical fiber, to suppress magneto-optic effect, namely suppress the magnetic field of MR scanner to the interference of optical signal transmission.
Visual centre optical sensor components Za, motorium optical sensor components Zb, realize the detection to 2 dimension space distributions of the hemoglobin concentration of cortex and blood flow, adopt 32 Laser emission optical fiber 3 and 32 supported signal Transmission Fibers 4 to consist of visual centre optical sensor components Za, adopt 36 Laser emission optical fiber 3 and 36 supported signal Transmission Fibers 4 to consist of motorium optical sensor components Zb, be distributed in respectively the correspondence positions such as visual centre after head and brain, motorium, the corresponding signal transmission fiber 4 of Laser emission optical fiber 3.
Visual centre optical sensor components Za, 32 pairs of assemblies are placed in the visual centre correspondence position after brain, motorium optical sensor components Zb, 36 pairs of assemblies are placed in head motorium correspondence position.
The assay method principle of state M is, the 2 polynary light sources of dimension and the every a pair of light source of photo-detector group and detector output signal are a component, and important output two-dimensional matrix data will be determined spatiality M.The component sensing principle is, adopts the Wavelength modulation spectroscopy method of index moving average filtering, can realize real-time resolution, and control lag also can be breathed and top layer blood flow high-frequency signal noise filtering.
By the pulse power, infra-red laser diode, coupling fiber carrying device, Laser emission optical fiber 3, optical fiber receiving terminal, signal transmission fiber 4, Infrared Detectors, front discharge road and data acquisition unit, data handling system form optical sensor system.
Detection signal receives by fibre bundle by optic fibre connector and transfers to snowslide optical pickocff port, the snowslide optical pickocff obtains the spectral signal of variation, respectively by 32 road and 36 circuit-switched data harvesters, the signal of data acquisition unit collection is processed by computer, and the data formation law curve after processing is used for state-detection and judgement.
The wavelength-modulated signal, namely infrared diode laser and snowslide Infrared Detectors group sensing total hemoglobin, oxygen hemoglobin, deoxyhemoglobin concentration are to spectral absorption.Laser Power Devices drive the infrared diode laser drive current and make wavelength variations stride across 600nm to 1000nm, and modulation becomes ω=50MHz sine wave.Suppress the laser instrument 1/f noise by the quick adjustment wavelength.Light intensity after the Wavelength modulation spectroscopy method absorbs adopts lambert Bill (Beer-Lambert) law physical modeling, and is decomposed into the Fourier space that first-harmonic is ω on mathematics.
Reference signal, namely frequency is the cosine signal cos2 ω t of 2 ω.
Index moving average filtering (exponential moving average), be a kind of moving average filter (movingaverage, MA), its average weighted weight is larger for the new data of time shaft, can control and reduce time delay, satisfying requirement of real time.And energy filtering heart beating, breathing and surperficial blood flow noise.
The real-time concentration signal is namely through the light intensity signal of algorithm demodulation.Operative symbol is multiplier, be that Wavelength modulation spectroscopy signal and reference signal 2 ω sinusoidal signals multiply each other through multiplier, and the index moving average filter is low pass filter, because the Wavelength modulation spectroscopy signal carries first-harmonic ω frequency signal and harmonic component, pass through low pass filter through the reference signal modulation /demodulation, obtain wavelength-modulated signal 2 ω components, namely reflect the light intensity signal of real-time concentration signal.
Claims (6)
1. an optical sensor system, is characterized in that: comprise radiating portion and receiving unit; Radiating portion is comprised of the pulse power, infra-red laser diode, coupling fiber carrying device and Laser emission optical fiber (3), and the pulse power, infra-red laser diode, coupling fiber carrying device and Laser emission optical fiber (3) are electrically connected to successively; Receiving unit is by optical fiber receiving terminal, signal transmission fiber (4), Infrared Detectors, front discharge road and data acquisition unit, data handling system form, optical fiber receiving terminal, signal transmission fiber (4), Infrared Detectors, front discharge road is electrically connected to successively with data acquisition unit, data handling system; Laser emission optical fiber (3) is corresponding with signal transmission fiber (4), the corresponding signal transmission fiber (4) of a Laser emission optical fiber (3); Laser emission optical fiber (3) and signal transmission fiber (4) alternately are placed on line concentration pad (2), form visual centre optical sensor components Za and motorium optical sensor components Zb.
2. optical sensor system according to claim 1, it is characterized in that: the material of described line concentration pad (2) is the pyrolytic graphite foamed materials.
3. optical sensor system according to claim 1 is characterized in that: described visual centre optical sensor components Za is made of three twelve earthly branches Laser emission optical fiber (3) and three twelve earthly branches signal transmission fibers (4).
4. optical sensor system according to claim 1 is characterized in that: described motorium optical sensor components Zb is made of 36 Laser emission optical fiber (3) and 36 supported signal Transmission Fibers (4).
5. optical sensor system according to claim 1, it is characterized in that: described Laser emission optical fiber (3) is hi bi birefringence fiber.
6. optical sensor system according to claim 1, it is characterized in that: described signal transmission fiber (4) is hi bi birefringence fiber.
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CN109313697A (en) * | 2017-02-23 | 2019-02-05 | 深圳市汇顶科技股份有限公司 | Sensing device |
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CN109313697A (en) * | 2017-02-23 | 2019-02-05 | 深圳市汇顶科技股份有限公司 | Sensing device |
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