CN202881276U - Equipment for low-temperature vaccine antigen inactivation process - Google Patents

Equipment for low-temperature vaccine antigen inactivation process Download PDF

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Publication number
CN202881276U
CN202881276U CN 201220572937 CN201220572937U CN202881276U CN 202881276 U CN202881276 U CN 202881276U CN 201220572937 CN201220572937 CN 201220572937 CN 201220572937 U CN201220572937 U CN 201220572937U CN 202881276 U CN202881276 U CN 202881276U
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CN
China
Prior art keywords
tank
deactivation
vaccine antigen
water tank
equipment
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CN 201220572937
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Chinese (zh)
Inventor
江兴华
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Zhaofenghua Biotechnology Fuzhou Co ltd
Original Assignee
FUZHOU DA BEI NONG BIOTECH Co Ltd
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Priority to CN 201220572937 priority Critical patent/CN202881276U/en
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Publication of CN202881276U publication Critical patent/CN202881276U/en
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Abstract

The utility model discloses equipment for a low-temperature vaccine antigen inactivation process. The equipment comprises a water tank, a circulating water pump, an inactivation tank and a control device, wherein an output pipe of the water tank is connected with an input pipe of the circulating pump; an output pipe of the circulating water pump is connected with an input pipe of the inactivation tank; an output pipe of the inactivation tank is connected with an input pipe of the water tank; the control device is electrically connected with the circulating water pump, the water tank and the inactivation tank respectively; and a refrigerating pipe and a heating pipe are fixedly coiled on the inner surface of the water tank, and electrically connected with the control device respectively. According to the equipment for the low-temperature vaccine antigen inactivation process, the refrigerating pipe and the heating pipe are arranged in the water tank, so that the vaccine antigen inactivation process can be completed both at a high temperature (37 DEG C) and a low temperature (4 DEG C), and the vaccine antigen inactivation process requiring high temperature and low temperature cooperation can be completed. Furthermore, the switching operation of a high-temperature inactivation process and low-temperature inactivation process by using the vaccine antigen is extremely convenient.

Description

A kind of equipment that can be used for low temperature vaccine antigen inactivation technology
Technical field
The utility model relates to vaccine antigen (comprising virus type and bacterium class) deactivation equipment, relates in particular to the equipment that can be used for low temperature vaccine antigen inactivation technology.
Background technology
The antigen deactivation equipment of vaccine is a kind of equipment of the deactivation for vaccine antigen.Currently available vaccines, existing vaccines antigen deactivation equipment comprises the deactivation tank, control device, heating water tank, water circulating pump and associated conduit, general vaccine antigen inactivation technology is the vaccine antigen adding deactivation tank with required deactivation, add simultaneously an amount of inactivator, the heating system of opening in the heating water tank by control device control is heated to 37 ℃ with the water in the heating water tank, the ON cycle water pump makes the hot water of heating water tank enter the chuck of deactivation tank, and then be circulated back to heating water tank, its interior heating system was with Automatic-heating after the water temperature of heating water tank descended, and water circulates in deactivation tank and heating water tank the vaccine antigen in the deactivation tank is carried out deactivation.Control device can be set start and stop pitch time, the temperature in the heating water tank and some other parameters of the agitator in the deactivation tank.
Use comparative maturity of technology that currently available vaccines, existing vaccines antigen deactivation equipment carries out deactivation to vaccine antigen, but general vaccine inactivation equipment can only be used for the vaccine antigen deactivation of conventional high temperature (generally being about 37 ℃) at present, the temperature of deactivation is about 37 ℃, when vaccine antigen changes inactivation technology, need to be in the environment of low temperature (about 4 ℃) during deactivation, existing equipment can't use, and can not carry out the vaccine antigen inactivation technology about 4 ℃.Simultaneously, when also having at present the inactivation technology of part vaccine antigen need use simultaneously the special process that high temperature and low temperature is used in conjunction with, currently available vaccines, existing vaccines antigen deactivation equipment can not satisfy the demands.
Summary of the invention
The purpose of this utility model provides a kind of high temperature (about 37 ℃) inactivation technology that can carry out simultaneously can carry out again low temperature (about 4 ℃) inactivation technology or low temperature (about 4 ℃) cooperate inactivation technology with high temperature (about 37 ℃) the equipment that can be used for low temperature vaccine antigen inactivation technology.
For achieving the above object, a kind of equipment that can be used for low temperature vaccine antigen inactivation technology of the utility model, it comprises water tank, water circulating pump, deactivation tank and control device, the output tube of described water tank is connected with the input tube of water circulating pump, the output tube of water circulating pump is connected with the input tube of deactivation tank, the output tube of deactivation tank is connected with the input tube of water tank, control device is electrically connected with water circulating pump, water tank and deactivation tank respectively, the internal surface of described water tank coils respectively and is fixed with refrigerator pipes and heats pipe, refrigerator pipes and heat pipe and be electrically connected with control device respectively.
Adopt above structure, in water tank, be provided with refrigerator pipes and heat pipe, can not only satisfy high temperature (about the 37 ℃) inactivation technology of existing vaccine antigen, low temperature (about 4 ℃) inactivation technology or the vaccine antigen low temperature (about 4 ℃) that can also satisfy vaccine antigen cooperate inactivation technology with high temperature (about 37 ℃).
Be respectively equipped with by-pass valve control on the output terminal of described water tank, water circulating pump, deactivation tank.Output liquid amount by the corresponding control of each by-pass valve control water tank, water circulating pump, deactivation tank.
Described deactivation tank comprises outer chuck and deactivation tank body, and the input tube of deactivation tank and output tube are communicated with outer chuck respectively.Input tube by the deactivation tank is input to the heating liquid in the water tank or refrigerant liquid in the outer chuck of deactivation tank, realizes that by the output tube of deactivation tank heating liquid or refrigerant liquid circulate between water tank and the outer chuck of deactivation tank again.
Be provided with agitator in the described deactivation tank body, agitator is electrically connected with control device, and control device can be controlled the start and stop pitch time of the agitator in the deactivation tank, and then finishes the inactivation technology of vaccine antigen.
Described control device is provided with regulating and controlling refrigerator pipes temperature respectively, heats the control panel of fluid temperature in pipe temperature, the water tank.By the setting of button on the control panel, can easily the vaccine antigen inactivation technology be switched under high temperature or low temperature.
The equipment of vaccine antigen inactivation technology of the present utility model, in water tank, be provided with refrigerator pipes and heat pipe, the vaccine antigen inactivation technology not only can be finished under high temperature (about 37 ℃), can also under low temperature (about 4 ℃), finish, simultaneously, can also finish the vaccine antigen inactivation technology that needs in high temperature and low temperature cooperation.In addition, the high-temperature inactivation technique of above vaccine antigen and the blocked operation of low temperature inactivation technology are extremely convenient, can finish on the control panel of control device.
Description of drawings
Below in conjunction with the drawings and specific embodiments the utility model is described in further detail:
Fig. 1 is the structural representation that the utility model can be used for the equipment of low temperature vaccine antigen inactivation technology.
Embodiment
As shown in Figure 1, the utility model comprises water tank 1, water circulating pump 2, deactivation tank 3 and control device 4, the output tube 11 of described water tank 1 is connected with the input tube 21 of water circulating pump 2, the output tube 22 of water circulating pump 2 is connected with the input tube 31 of deactivation tank 3, the output tube 32 of deactivation tank 3 is connected with the input tube 12 of water tank 1, control device 4 is electrically connected with water circulating pump 2, water tank 1 and deactivation tank 3 respectively, the internal surface of described water tank 1 coils respectively and is fixed with refrigerator pipes 5 and heats pipe 6, refrigerator pipes 5 and heat pipe 6 and be electrically connected with control device 4 respectively.
Adopt above structure, in water tank 1, be provided with respectively refrigerator pipes 5 and heat pipe 6, when the inactivation technology of vaccine antigen needs high temperature (about 37 ℃), adopt the liquid that heats in 6 pairs of water tanks 1 of pipe to heat, and then the liquid after the heating in the water tank 1 is heated deactivation tank 3; When the inactivation technology of vaccine antigen needs low temperature (about 4 ℃), adopt the liquid in 5 pairs of water tanks 1 of refrigerator pipes to freeze, and then the liquid after the refrigeration in the water tank 1 is freezed to deactivation tank 3.Vaccine antigen deactivation equipment of the present utility model like this is in the production process of vaccine, can not only satisfy high temperature (about the 37 ℃) inactivation technology of existing vaccine antigen, low temperature (about 4 ℃) inactivation technology or the vaccine antigen low temperature (about 4 ℃) that can also satisfy vaccine antigen cooperate inactivation technology with high temperature (about 37 ℃).
Liquid in the described water tank 1 is the mixing solutions of propylene glycol and water.
Be respectively equipped with by-pass valve control 7 on the output terminal of described water tank 1, water circulating pump 2, deactivation tank 3.Output liquid amount by each by-pass valve control 7 corresponding control water tank 1, water circulating pump 2, deactivation tank 3.
Described deactivation tank 3 comprises outer chuck 33 and deactivation tank body 34, and the input tube 31 of deactivation tank 3 and output tube 32 are communicated with outer chuck 33 respectively.Input tube 31 by deactivation tank 3 is input to the heating liquid in the water tank 1 or refrigerant liquid in the outer chuck 33 of deactivation tank 3, the again conduction by the outer chuck 33 of deactivation tank, deactivation tank body 34 is heated or cools off, and then the vaccine antigen inactivation technology that carries out in the deactivation tank body 34 is carried out under high temperature or low temperature.In addition, realize heating liquid or refrigerant liquid circulation between water tank 1 and the outer chuck 33 of deactivation tank by the output tube 34 of deactivation tank 3.
Be provided with agitator 35 in the described deactivation tank body 34, agitator 35 is electrically connected with control device 4, and control device 4 can be controlled the start and stop pitch time of the agitator 35 in the deactivation tank 3, and then finishes the inactivation technology of vaccine antigen.
Described control device 4 is provided with regulating and controlling refrigerator pipes 5 temperature respectively, heats the control panel 41 of pipe 6 temperature, water tank 1 interior fluid temperature.By the setting of button on the control panel 41, can easily the vaccine antigen inactivation technology be switched under high temperature or low temperature.
Adopt vaccine antigen deactivation equipment of the present utility model, when needs carry out the vaccine antigen inactivation technology under low temperature (about 4 ℃), setting by the control panel 41 in the control device 4, open refrigerator pipes 5, liquid in 5 pairs of water tanks 1 of refrigerator pipes freezes, then by water circulating pump 2 liquid that has freezed in the water tank 1 is transported to the outer chuck 33 of deactivation tank 3, by outer chuck 33 conduction of deactivation tank, deactivation tank body 34 is freezed, the vaccine antigen inactivation technology in the deactivation tank body 34 is finished at low temperatures.Simultaneously, realize refrigerant liquid circulation between water tank 1 and the outer chuck 33 of deactivation tank by the output tube 32 of deactivation tank 3.When the fluid temperature in the water tank 1 rose, refrigerator pipes 5 was freezed to the liquid in the water tank 1 automatically.
When vaccine antigen need to carry out high temperature (about 37 ℃) deactivation or the high temperature in deactivation later stage (about 37 ℃) processing, setting in the switching controls panel 41, start pipe 6 work that heat, the liquid that heats in 6 pairs of water tanks 1 of pipe heats, make fluid temperature reach the temperature of setting, then by water circulating pump 2 heating liquids is transported to the outer chuck 33 of deactivation tank 3, vaccine antigen inactivation technology in the deactivation tank body 34 is at high temperature finished, the antigen vaccine deactivation later stage is at high temperature processed.

Claims (5)

1. equipment that can be used for low temperature vaccine antigen inactivation technology, it comprises water tank, water circulating pump, deactivation tank and control device, the output tube of described water tank is connected with the input tube of water circulating pump, the output tube of water circulating pump is connected with the input tube of deactivation tank, the output tube of deactivation tank is connected with the input tube of water tank, control device is electrically connected with water circulating pump, water tank and deactivation tank respectively, it is characterized in that: the internal surface of described water tank coils respectively and is fixed with refrigerator pipes and heats pipe, refrigerator pipes and heat pipe and be electrically connected with control device respectively.
2. the equipment that can be used for low temperature vaccine antigen inactivation technology according to claim 1 is characterized in that: be respectively equipped with by-pass valve control on the output terminal of described water tank, water circulating pump, deactivation tank.
3. the equipment that can be used for low temperature vaccine antigen inactivation technology according to claim 1, it is characterized in that: described deactivation tank comprises outer chuck and deactivation tank body, and the input tube of deactivation tank and output tube are communicated with outer chuck respectively.
4. the equipment that can be used for low temperature vaccine antigen inactivation technology according to claim 3, it is characterized in that: be provided with agitator in the described deactivation tank body, agitator is electrically connected with control device.
5. the equipment that can be used for low temperature vaccine antigen inactivation technology according to claim 1 is characterized in that: described control device is provided with regulating and controlling refrigerator pipes temperature respectively, heats the control panel of fluid temperature in pipe temperature, the water tank.
CN 201220572937 2012-10-31 2012-10-31 Equipment for low-temperature vaccine antigen inactivation process Expired - Lifetime CN202881276U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201220572937 CN202881276U (en) 2012-10-31 2012-10-31 Equipment for low-temperature vaccine antigen inactivation process

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 201220572937 CN202881276U (en) 2012-10-31 2012-10-31 Equipment for low-temperature vaccine antigen inactivation process

Publications (1)

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CN202881276U true CN202881276U (en) 2013-04-17

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112263687A (en) * 2020-10-30 2021-01-26 江苏中慧元通生物科技有限公司 High-efficient inactivation device of bacterin
CN115738985A (en) * 2022-10-27 2023-03-07 黄山邦森新材料有限公司 Tubular reaction system for producing ultra-low molecular weight povidone

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112263687A (en) * 2020-10-30 2021-01-26 江苏中慧元通生物科技有限公司 High-efficient inactivation device of bacterin
CN115738985A (en) * 2022-10-27 2023-03-07 黄山邦森新材料有限公司 Tubular reaction system for producing ultra-low molecular weight povidone

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C14 Grant of patent or utility model
GR01 Patent grant
CP01 Change in the name or title of a patent holder

Address after: Gushan Town Park in Jinan District of Fuzhou city in Fujian province village 110 350000

Patentee after: Zhaofenghua Biotechnology (Fuzhou) Co.,Ltd.

Address before: Gushan Town Park in Jinan District of Fuzhou city in Fujian province village 110 350000

Patentee before: FUZHOU DA BEI NONG BIOTECH Co.,Ltd.

CP01 Change in the name or title of a patent holder
CX01 Expiry of patent term

Granted publication date: 20130417

CX01 Expiry of patent term