CN202779013U - Washing and drying device of biochips - Google Patents
Washing and drying device of biochips Download PDFInfo
- Publication number
- CN202779013U CN202779013U CN 201220290183 CN201220290183U CN202779013U CN 202779013 U CN202779013 U CN 202779013U CN 201220290183 CN201220290183 CN 201220290183 CN 201220290183 U CN201220290183 U CN 201220290183U CN 202779013 U CN202779013 U CN 202779013U
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- China
- Prior art keywords
- drying device
- clearing
- connecting plate
- cleaning box
- biochips
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Abstract
The utility model discloses a washing and drying device of biochips. The washing and drying device of the biochips comprises a cylinder, a clamping jaw and a washing box. A first nozzle holder and a second nozzle holder are correspondingly arranged in the washing box in a front-back mode, air nozzle holders are correspondingly arranged in the washing box in a left-right mode, and the other end of a shaft which is connected with the nozzle holders and the air nozzle holders in a rotating mode is connected in a guiding mode with a shaft connecting plate on the outer end face of the washing box through a long hole formed in the washing box. By means of the washing and drying device of the biochips, the problems that the biochips can not be washed cleanly, washing pressure and flow can not be quantized, and the washing positions can not be adjusted are solved, and the problems that the biochips can not be completely washed or are washed excessively, biological samples arranged on the surfaces of the biochips in an array are damaged or polluted by one another, and the biochips can not be dried completely are solved at the same time.
Description
Technical field
The present invention relates to a kind of clearing and drying device, relate in particular to a kind of clearing and drying device of biochip.
Background technology
Hard matrix chip is clamped to and cleans and drying area, adopt circular staight needle pipe fixed position externally to spray liquid, same fixed position firm discharge and the pressure of adopting externally sprays gas, chip is driven by clamping device and moves up and down, the injection of a liquids and gases obverse and reverse for hard matrix chip.The distance of hydro-peening and air blowing, pressure, flow, angle can't be adjusted and control, and cause cleaning deficiency or overclean, the destroyed or mutual pollution of the biological sample of chip surface array, and the side can't dry up, and the liquid residue chip has a strong impact on next step technique.
Summary of the invention
The present invention seeks to provide for the defective that prior art exists a kind of clearing and drying device of biochip.
The present invention adopts following technical scheme for achieving the above object:
A kind of clearing and drying device of biochip, comprise cylinder, jaw, cleaning box, correspondence arranges first, second nozzle carrier before and after in the described cleaning box, correspondence arranges the air nozzle seat about in the cleaning box, is connected with the axle connecting plate guiding of cleaning box outer face by the slotted hole that described cleaning box is provided with the axle other end that described nozzle carrier, air nozzle seat are rotationally connected.
Described first, second nozzle carrier, air nozzle seat and axle connecting plate are provided with the fastening bolt that can be connected on the described axle.
Described axle connecting plate and described axle are that nonrotational mode is connected.
Described axle connecting plate be provided with a plurality of can about adjust the hex bolts of axle connecting plate relative position.
The chip cleaning needle that is provided with the array pin hole and matches with described pin hole on the bottom water spout seat of described the first nozzle carrier, described cleaning needle internal diameter 0.2 mm, external diameter 0.6mm.
The side of described cleaning box is provided with horizontal pressing plate.
Described cleaning box bottom is provided with tap, and described tap is by the effluent discharge of sewer pipe joint.
The nozzle width of described air nozzle seat is slightly larger than the chip width.
The die gap of described air nozzle seat is 0.3-0.4mm, width 5-6mm.
The present invention has following beneficial effect: solved the flushing unclean, flushing pressure, the problem that flow can't quantize and the position can't be adjusted, cleaning deficiency or overclean have been solved simultaneously, the destroyed or mutual pollution of the biological sample of chip surface array, the fully problem of drying; 4 very thin air nozzles, at 4 faces, two positive and negatives facing to hard matrix chip, two two sides facing to hard matrix chip, each nozzle can the implementation space three-dimensional adjustment (X-direction, Y-direction, the anglec of rotation), add chip itself and moved up and down by mechanisms grip, consisted of the comprehensive adjustment of 4 dimensions, realize that blowing is to the comprehensive covering of chip.
Tow sides at chip are provided with fluid injector, and the front is 7 nozzle needles, and reverse side is 1 nozzle needle.Nozzle needle can be realized the adjustment of 3 dimensions equally, adds chip itself and is moved up and down by mechanisms grip, has consisted of the comprehensive adjustment of 4 dimensions, realizes that the comprehensive cleaning that liquid sprays chip covers.
Positive jet and fluid injector structurally is designed to integral type, and the jet and fluid injector of reverse side structurally also is designed to integral type.
For chip, according to predetermined imagination, carry out first jet cleaning, then dry up; Also can dry up rear continuation and clean, and then dry up.
The liquid jet cleaning time can be controlled separately, and the time that dries up also can be controlled separately, and the pressure of liquid and flow can be regulated separately; The jet time can be controlled separately, and pressure and flow also can be regulated separately.
Description of drawings
Fig. 1: structure principle chart of the present invention.
The B-B profile of Fig. 2: Fig. 1.
The partial enlarged drawing of Fig. 3: Fig. 2.
The A-A profile of Fig. 4: Fig. 1.
Fig. 5: the partial enlarged drawing of Fig. 4 II.
Fig. 6: general assembly axonometric drawing of the present invention.
The specific embodiment
Shown in Fig. 1-6, the present invention is a kind of clearing and drying device of biochip, comprise cylinder 1, jaw 2, cleaning box 4, described cleaning box 4 interior front and back correspondences arrange first, second nozzle carrier 5,8, correspondence arranged air nozzle seat 7 about cleaning box 4 was interior, was connected with axle connecting plate 13 guiding of cleaning box 4 outer faces by the slotted hole that described cleaning box 4 is provided with axle 6 other ends that described first, second nozzle carrier 5,8, air nozzle seat 7 are rotationally connected.Described first, second nozzle carrier 5,8, air nozzle seat 7 and axle connecting plate 13 are provided with the fastening bolt 16 that can be connected on the described axle.Described axle connecting plate 13 and described axle 6 are connected for nonrotational mode.Preferably, usually use square hole to cooperate guiding with square shaft.Described axle connecting plate 13 be provided with a plurality of can about adjust the hex bolts 15 of axle connecting plate 13 relative positions.The chip cleaning needle 14 that is provided with the array pin hole and matches with described pin hole on the bottom water spout seat of described the first nozzle carrier 5, described cleaning needle internal diameter 0.2 mm, external diameter 0.6mm.The side of described cleaning box 4 is provided with horizontal pressing plate 9.Described cleaning box 4 bottoms are provided with tap, and described tap is by 10 effluent discharges of sewer pipe joint.The nozzle width of described air nozzle seat 7 is slightly larger than the chip width.The die gap of described air nozzle seat 7 is 0.3-0.4mm, width 5-6mm.
The anterior water spout seat of the first nozzle carrier 5 arranges the array pin hole, and the bottom water spout seat of the first nozzle carrier 5 arranges 7 chip cleaning needles, and second nozzle seat 8 is designed to 1 cleaning needle 14, described pin hole internal diameter 0.2 mm external diameter 0.6mm.
The present invention has the tow sides water spray altogether, the positive and negative two sides that add, and the four sides is jet; Double-edged water spray and jet the design respectively on same carrier.
Glass matrix biochip 3 single face lattice array bioproteins, surface-closed, after bioprotein chip and the seroreaction, need to be from cleaning and the drying of dividing, to carry out next step technique.
Clean
Adopt 4+3 array pin hole, the aperture of 0.2---0.6mm, positive seven, one of reverse side, the front is used for washing the front of the bioprotein of biochip, the reverse side of a pin flushing of reverse side chip.
The width range of flushing covers the width of chip, and 4+3 array pin hole staggers up and down all and distribution, to reach all the purpose with cleaning.
It is stainless steel that cleaning needle is installed carrier, lateral inflow, water spray pressure and time can be regulated, carrier inclination angle capable of regulating is installed, two dimension capable of regulatings in horizontal plane, when moving up and down manually or automatically, can be implemented in adjustment on the four dimensions in conjunction with above adjustment mode, to reach the effect of abundant cleaning with the chip of handle.
Dry
Clean after the end, adopt Medical purification air blow drying chip.
Adopt stainless steel to be processed into spray nozzle of atmospheric pressure, nozzle width is slightly larger than the chip width, jet slit is 0.3-0.4mm, protrude thin mouth type to save the space, but valve in the plane both direction is regulated, and the anglec of rotation can be regulated, and chip is when moving up and down manually or automatically, can realize 4 position adjustment on the dimension, comprehensively dry up effect to reach.Chip all arranges air nozzle at 4 faces, and each valve has same adjustable function, and air blowing flow, pressure and time can be controlled separately by external equipment.
The gas oven dry efficiently solves the chip surface residual moisture, the problem of handle and chip residual moisture.
The double-edged nozzle of chip of the present invention and the jet integral type that is designed to, the blowing nozzle of side designs separately.
The above only is preferred embodiment of the present invention, and is in order to limit the present invention, within the spirit and principles in the present invention not all.Any modification of doing, be equal to replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. the clearing and drying device of a biochip, comprise cylinder, jaw, cleaning box, it is characterized in that, correspondence arranges first, second nozzle carrier before and after in the described cleaning box, correspondence arranges the air nozzle seat about in the cleaning box, is connected with the axle connecting plate guiding of cleaning box outer face by the slotted hole that described cleaning box is provided with the axle other end that described nozzle carrier, air nozzle seat are rotationally connected.
2. the clearing and drying device of a kind of biochip according to claim 1 is characterized in that, described first, second nozzle carrier, air nozzle seat and axle connecting plate are provided with the fastening bolt that can be connected on the described axle.
3. the clearing and drying device of a kind of biochip according to claim 1 is characterized in that, described axle connecting plate and described axle are that nonrotational mode is connected.
4. according to claim 1 and 2 or the clearing and drying device of 3 described a kind of biochips, it is characterized in that described axle connecting plate and described axle are that square hole and square shaft are connected.
5. the clearing and drying device of a kind of biochip according to claim 4 is characterized in that, described axle connecting plate be provided with a plurality of can about adjust the hex bolts of axle connecting plate relative position.
6. the clearing and drying device of a kind of biochip according to claim 1, it is characterized in that, the chip cleaning needle that is provided with the array pin hole and matches with described pin hole on the bottom water spout seat of described the first nozzle carrier, described cleaning needle internal diameter 0.2 mm, external diameter 0.6mm.
7. the clearing and drying device of a kind of biochip according to claim 1 is characterized in that, the side of described cleaning box is provided with horizontal pressing plate.
8. the clearing and drying device of a kind of biochip according to claim 1 is characterized in that, described cleaning box bottom is provided with tap, and described tap is by the effluent discharge of sewer pipe joint.
9. the clearing and drying device of a kind of biochip according to claim 1 is characterized in that, the nozzle width of described air nozzle seat is slightly larger than the chip width.
10. the clearing and drying device of a kind of biochip according to claim 1 is characterized in that, the die gap of described air nozzle seat is 0.3-0.4mm, width 5-6mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220290183 CN202779013U (en) | 2012-06-19 | 2012-06-19 | Washing and drying device of biochips |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220290183 CN202779013U (en) | 2012-06-19 | 2012-06-19 | Washing and drying device of biochips |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202779013U true CN202779013U (en) | 2013-03-13 |
Family
ID=47806356
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201220290183 Expired - Lifetime CN202779013U (en) | 2012-06-19 | 2012-06-19 | Washing and drying device of biochips |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202779013U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102814294A (en) * | 2012-06-19 | 2012-12-12 | 江苏三联生物工程有限公司 | Cleaning and drying device for biological chip |
| CN105107784A (en) * | 2015-09-11 | 2015-12-02 | 港龙生物技术（深圳）有限公司 | High-throughput automatic cleaning system for microarray chip and using method |
| CN106322961A (en) * | 2015-06-23 | 2017-01-11 | 胡妍 | Drying devices of white spirit bottle drying machine |
-
2012
- 2012-06-19 CN CN 201220290183 patent/CN202779013U/en not_active Expired - Lifetime
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102814294A (en) * | 2012-06-19 | 2012-12-12 | 江苏三联生物工程有限公司 | Cleaning and drying device for biological chip |
| CN102814294B (en) * | 2012-06-19 | 2015-02-18 | 江苏三联生物工程有限公司 | Cleaning and drying device for biological chip |
| CN106322961A (en) * | 2015-06-23 | 2017-01-11 | 胡妍 | Drying devices of white spirit bottle drying machine |
| CN106482481A (en) * | 2015-06-23 | 2017-03-08 | 胡妍 | A kind of drying unit of Chinese liquor bottle dehydrator |
| CN106556227A (en) * | 2015-06-23 | 2017-04-05 | 胡妍 | A kind of drying unit of Chinese liquor bottle dehydrator |
| CN105107784A (en) * | 2015-09-11 | 2015-12-02 | 港龙生物技术（深圳）有限公司 | High-throughput automatic cleaning system for microarray chip and using method |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20130313 |
|
| CX01 | Expiry of patent term |