CN202776541U - Controllable renal artery radiofrequency ablation electrode conduit - Google Patents
Controllable renal artery radiofrequency ablation electrode conduit Download PDFInfo
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- CN202776541U CN202776541U CN 201220348382 CN201220348382U CN202776541U CN 202776541 U CN202776541 U CN 202776541U CN 201220348382 CN201220348382 CN 201220348382 CN 201220348382 U CN201220348382 U CN 201220348382U CN 202776541 U CN202776541 U CN 202776541U
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Abstract
The utility model relates to a medical instrument for interventional therapy, in particular to a controllable renal artery radiofrequency ablation electrode conduit for curing resistant hypertension by entering a renal artery via the skin and blood vessels, and mainly aims to solve the technical problem for effectively eliminating sympathetic nerves on the wall of the renal artery and reducing damages to the inner walls of the blood vessels. The controllable renal artery radiofrequency ablation electrode conduit is provided with a conduit body, an electrode is connected at the remote end of the conduit body, an operation handle is connected at the near end of the conduit body, an ablation electrode and a monitoring electrode are axially arranged at the remote end of the conduit body, and a gap is reserved between the ablation electrode and the monitoring electrode. Compared with the prior art, the controllable renal artery radiofrequency ablation electrode conduit has the advantages that an infusion hole is reserved on the ablation electrode, the monitoring electrode is adjacent to the ablation electrode via the gap and used for monitoring the temperature of sympathetic nervous tissue being ablated so as to judge whether a required value for clinic therapy is reached or not, and in addition, conduction of sympathetic nerve signals can be acquired via the monitoring electrode, so that wave forms of sympathetic nerve conductions before and after ablation are compared to assist to judge whether an operation endpoint is finished or not.
Description
Technical field
This utility model relates to a kind of medical apparatus and instruments of interventional therapy, particularly a kind of for percutaneous, blood vessel, enter the frequency ablation electrode catheter of renal artery treatment intractable hypertension.
Background technology
The whole world probably has nearly adult of 1/5th to 1/3rd to suffer from hypertension, and hypertension causes 7,500,000 people dead every year, and it is the first that mortality rate occupies the whole world.The every increase of adult's blood pressure 20/10mmHg, then the mortality rate of cardiovascular disease doubles.Make great efforts better to diagnose and control hypertension although the medical personnel has strengthened, the patient who also only only has half to receive treatment has realized set blood pressure index.Traditional medicine control therapeutic scheme, the ineffectivity of patient's compliance, doctor's inertia, side effects of pharmaceutical drugs and medicine all is the factor that causes controlling weak effect, Europe does not allow to use ACE or the treatment of ARB associating aliskiren to the patient of diabetes or eGFR＜60 now, namely medicine is more and more unable to do what one wishes to the treatment of intractable hypertension, and numerous doctors and patients thirst for occurring new Therapeutic Method.
Intractable hypertension is more common clinically, and paathogenic factor is numerous, and pathogenesis is indefinite, and medication effect is very poor.Medical circle thinks that always sympathetic activation and the hypertension of kidney are in close relations, and the kidney sympathetic nerve is proved to be the cause that hypertension occurs and keeps already.The result that the Symplicity HTN-2 that at first goes to kidney sympathetic nerve radio frequency ablation catheter system (Medtronic Ardian) to carry out that reports in the recent period studies, in this research, researcher utilizes the Symplicity conduit system to transmit the radio frequency energy in the renal artery tube chamber, melt adventitial afferent renal nerve and nervus centrifugalis, compare with the patient who only relies on Drug therapy control blood pressure simultaneously, the safety and the effectiveness that use percutaneous catheter ablation intractable hypertension are described, this method has shown that physiological knowledge is converted into a major progress of particular treatment target.According to Esler etc., compare matched group, test group patient's clinic blood pressure had one significantly to reduce at 1 month, 3 months, 6 months.The small sample result of the test shows to be effective in two years at least.Blood vessel is very safe after also showing radiofrequency ablation therapy in the report, in 14 ~ 30 days 18 routine patients has been carried out Angiography Evaluation behind the radiofrequency ablation therapy, does not find damage or unusual at arteriorenal radio-frequency (RF) ablation point.Similarly, 124 routine patients in Symplicity HTN-1 and the Symplicity HTN-2 research are carried out after 6 months image check do not find the adverse events relevant with radio-frequency (RF) ablation, and their central major part has all been done CT or MR angiography or kidney doppler imaging.Without renal artery pathology damages, show that itself and high power RF ablation of atrial and pulmonary vein treat arrhythmia and cause thrombosis and narrow significant difference arranged behind the radiofrequency ablation therapy.
Kidney sympathetic nerve radio-frequency (RF) ablation (renal artery melts) art is to melt a helix in renal artery, effectively cuts off on the one hand whole sympathetic nerve, reduces on the other hand the renal artery inner film injury, avoids renal artery stenosis.At present, the renal artery ablation that carries out is both at home and abroad all not yet set up clear and definite operation terminal point.Take Medtronic Ardian as example, its operation terminal point is that the ablating electrode temperature reaches more than 50 ℃, and impedance reduces more than 10%.But this terminal point does not show and has carried out melting fully that stopping operation has sizable blindness.The another kind of method of prior art is that the ARR ablation catheter of employing treatment melts the sympathetic nerve on the renal artery, reach the purpose for the treatment of intractable hypertension, this kind ablation catheter diameter is thicker, in the renal artery blood vessel, handle inconvenient, and it is larger to melt area, and renal artery is caused larger damage.
Summary of the invention
The purpose of this utility model provides a kind of renal artery radiofrequency ablation controllable electrodes conduit, and the technical problem that solve is the sympathetic nerve of effectively removing on the renal artery tube wall, reduces the damage to blood vessel.
Renal artery radiofrequency ablation controllable electrodes conduit of the present utility model is provided with catheter tube, and the far-end of catheter tube is connected with electrode, and near-end is connected with control handle, and described electrode is ablating electrode and monitoring electrode.
Ablating electrode of the present utility model and monitoring electrode are arranged on far-end along the axis setting of catheter tube, are provided with the interval between ablating electrode and the monitoring electrode.
Ablating electrode of the present utility model adopts platinumiridio hollow bar or pipe, and distal end is circular shape, has the cold brine perfusion hole on the ablating electrode.
Ablating electrode external diameter 1mm-2.67mm of the present utility model, long 1mm-4mm, the cold brine perfusion hole is 1-20, the aperture is 0.1mm-0.4mm, is distributed on the distal end and tube wall of ablating electrode.
Monitoring electrode of the present utility model is ring-type, external diameter 1mm-2.67mm, long 0.4mm-1mm.
In the monitoring electrode of the present utility model temperature element is housed.
Temperature element of the present utility model is arranged in the monitoring electrode retaining collar in vertically the groove.
This utility model ablating electrode and monitoring are spaced apart 0.2mm-2mm between the electrode.
Ablating electrode external diameter 1.25mm of the present utility model, long 1.6mm has 9 cold brine perfusion holes on the ablating electrode, and wherein 3 cold brine perfusion holes are evenly distributed on electrode tip, and 6 cold brine perfusion holes are evenly distributed on the tube wall at ablating electrode middle part; Described monitoring electrode external diameter 1.33mm, long 0.6mm; Described temperature element is thermocouple; The described 0.5mm that is spaced apart.
Control handle of the present utility model is regulated catheter guide tube body far-end 6mm-75mm place's bending or is stretched, rotates to 120 ° or 60 °, and 72 °, 180 ° or 90 ° of positions.
This utility model compared with prior art; electrode is provided with an ablating electrode and a monitoring electrode; there is not fill orifice on the ablating electrode; the monitoring electrode is ring-type; through interval adjacent ablation electrode; the temperature of monitoring distance ablating electrode 0.5-2.5mm place parasympathetic tissue; thereby the temperature of monitoring ablation areas; each monitoring electrode interior is equipped with occasionally critesistor of temperature element thermoelectricity; the temperature of the parasympathetic tissue that monitoring is melted in ablation procedure reaches the clinical treatment required value with judgement, determines to melt terminal point; effectively melt guaranteeing; and minimizing is protected blood vessel to the damage of blood vessel, the conduction that also can obtain sympathetic signal by monitoring electrode; sympathetic nerve conduction waveform before and after contrast is melted, whether auxiliary judgment operation terminal point is finished.
Description of drawings
Fig. 1 is the structural representation of renal artery radiofrequency ablation controllable electrodes conduit of the present utility model.
Fig. 2 ablating electrode of the present utility model axially cuts open intention.
Fig. 3-the 1st, this utility model ablating electrode and Brine Pipe, wire and thermocouple assembling sketch map.
Fig. 3-the 2nd, the left view of Fig. 3-1.
Fig. 4 is ablating electrode of the present utility model and monitoring electrode assembling sketch map.
Fig. 5 is the sketch map of this utility model ablation areas.
Fig. 6 is catheter tube structural representation of the present utility model.
Fig. 7-the 1st, handle arrangement sketch map of the present utility model.
Fig. 7-the 2nd, handle right view of the present utility model.
Fig. 7-the 3rd, handle left view of the present utility model.
Fig. 7-the 4th, handle hands of the present utility model is pulled sketch map.
Fig. 8 is exemplary procedure ablation line sketch map of the present utility model.
The specific embodiment
Below in conjunction with drawings and Examples this utility model is described in further detail.
As shown in Figure 1, the renal artery radiofrequency ablation controllable electrodes conduit of this utility model embodiment from far-end to near-end, is linked in sequence by ablating electrode 1, monitoring electrode 2, catheter tube 3, control handle 4.Control handle 4 near-ends are extended with wire extended line 7, and the near-end of wire extended line 7 is electrically connected with adapter 8, and control handle 4 near-ends are connected with cool brine connection tube 9, cool brine connection tube 9 near-end jointings 10.Control handle 4 near-ends are holder handle 5, and the middle part of holder handle 5 is provided with hands and pulls 6, are used for regulating the angle of the bending of catheter tube 3 far-ends and rotation.Catheter tube 3 near-end outer rims are provided with the sounding mark scale 11 of white, are used for observing the degree of depth that control renal artery radiofrequency ablation controllable electrodes conduit enters the radio-frequency (RF) ablation position.
As shown in Figure 2, ablating electrode 1 adopts the platinumiridio hollow bar or manages 12, ablating electrode 1 external diameter 1mm-2.67mm, and long 1mm-4mm, present embodiment external diameter 1.25mm, long 1.6mm, distal end are circular shape 13.The cold brine perfusion hole 14 that to have 1-20 aperture on the ablating electrode 1 be 0.1mm-0.4mm, present embodiment is 9, the precise laser device that adopts Shenzhen laser company of big nation to produce processes, wherein 3 cold brine perfusion holes are evenly distributed on ablating electrode 1 distal end, 6 cold brine perfusion holes are evenly distributed on the tube wall at ablating electrode middle part, and the hole heart is apart from distal end 1mm.
Shown in Fig. 3-1, the near-end of ablating electrode 1 is provided with the monitoring electrode 2 of ring-type, and monitoring electrode 2 is electrically connected with temperature element line 15.Shown in Fig. 3-2, monitoring is equipped with temperature element 16 in the electrode 2, and temperature element 16 is arranged in monitoring electrode 2 rings in vertically the groove 17.Monitoring electrode 2 external diameter 1mm-2.67mm, long 0.4mm-1mm is used for measuring temperature, measures conduction sympathetic nerve current potential.Present embodiment external diameter 1.33mm, long 0.6mm, temperature element are thermocouples.
Be connected with the wire 18 of delivery of radio frequency energy in the ablating electrode 1, the far-end of wire 18 is electrically connected with ablating electrode 1.The far-end of cool brine connection tube 9 is to ablating electrode 1.
As shown in Figure 4, monitoring electrode 2 and ablating electrode 1 interval 19 between vertically is 0.2mm-2mm, and present embodiment is 0.5mm.
Radio-frequency (RF) ablation is that the rising by the parasympathetic tissue temperature on the renal artery tube wall realizes, when temperature reached 50 ℃, neurocyte can be downright bad, so the parasympathetic tissue temperature reaches more than 50 ℃, is to realize the sign that effectively melts.In the process of radio-frequency (RF) ablation, temperature be centered by ablating electrode 1 to external radiation, as shown in Figure 5, ablation areas also be centered by ablating electrode 1 outwards radially the expansion, the tissue regions that temperature reaches more than 50 ℃ is effective zone of ablation.Therefore can understand the size of true ablation areas by the temperature of monitoring ablating electrode 1 surrounding tissue, thereby determine whether to end radio-frequency (RF) ablation.
Present embodiment is provided with along the monitoring electrode 2 of the ring-type of the long 0.6mm of axis at the proximal location of distance ablating electrode 0.5mm, and thermocouple is housed in it, in order to monitor ablating electrode 1 temperature of parasympathetic tissue on every side.When the temperature that records of monitoring electrode 2 reaches 50 ℃, explanation along axis direction apart from the monitoring of the interval 0.5mm+ between ablating electrode near-end 1.1mm(monitoring electrode and ablating electrode electrode length 0.6mm=1.1mm) temperature located reached 50 ℃, at this moment, effectively the radio-frequency (RF) ablation zone is: be the long 1.6mm+ of 3.8mm(ablating electrode apart from ablating electrode 1.1mm * 2=3.8mm) along the length areas of axis, the zone of vertical axis is Φ 3.45mm(ablating electrode diameter 1.25mm+1.1mm * 2=Φ 3.45mm), the effective ablation areas that is to say each ablation points of present embodiment ablating electrode is 3.8mm * Φ 3.45mm.In conjunction with CT, MR angiography or the arteriorenal size of kidney doppler imaging outcome measurement of pre-operative patients, melting in can determining to perform the operation counted, and whole ablation procedure is pressed every effective coverage, forms a complete ablation line in renal artery.
As shown in Figure 6, catheter tube 3 long 750mm-1500mm, external diameter 1.33mm-2.67mm, internal diameter 0.50mm-1.50mm.The long 850mm of present embodiment catheter tube, external diameter 1.67mm, internal diameter 1.50mm.Catheter tube 3 is the same with the intervention body material of prior art, adopt the macromolecular material of good biocompatibility to form, the catheter tube that consists of is soft by firmly tapering to from near-end to far-end hardness, unlike the prior art be that the near-end of present embodiment catheter tube 3 adopts stainless steel tube 20, guarantee that the twisting property of conduit is near 1:1.The mid portion of catheter tube 3 adopts the multiple tube of polyfluortetraethylene pipe 21 and stainless steel cloth 22, guarantees that conduit has pliability, and the far-end of catheter tube 3 adopts nylon elastomer 23.By the control handle 4 of manipulate proximal end, distal end of catheter is flexible near monitoring electrode 2 place's 6-75mm sections.With the sounding mark scale 11 of adularescent, be used for accurately controlling the degree of depth that renal artery radiofrequency ablation controllable electrodes conduit enters the radio-frequency (RF) ablation position on the catheter proximal end stainless steel tube 20.
Shown in Fig. 7-1, Fig. 7-2, Fig. 7-3 and Fig. 7-4, control handle 4 is connected to form by the rotating handle 51 of far-end and holder handle 5 two parts of near-end.Rotating handle 51 is used for connecting duct body 3, and rotating handle 51 is provided with on the other hand and pulls 6, is used for conduit is rotated to suitable angle, and front and back are pulled hands and pulled the bending of 6 scalable catheter tubes, 3 far-end 6mm-75mm places or stretch.Holder handle 5 is used for the postrotational position of A/C, and present embodiment control handle 4 can rotate to three positions: 120 ° or 60 °, and 72 °, 180 ° or 90 °, be respectively applied to along the circumferential direction carry out or 6 points at 3,5 points, 2 or 4 radio frequencies melt.Control handle 4 crooked or stretch, rotation can be adopted the structure of prior art.
Exemplary procedure
1, renal artery radiofrequency ablation instrument
The renal artery radiofrequency ablation instrument that adopts is special-purpose ablatograph, is connected with renal artery radiofrequency ablation controllable electrodes conduit of the present utility model by a special-purpose cable that prolongs.The technical specification of renal artery radiofrequency ablation instrument is as follows:
Frequency 450-575 kilohertz;
Voltage 0-220 volt;
Electric current 0-2.0 peace;
Maximum 15 watts of power;
The limit upper limit is cut off in impedance: 500 ohm, and lower limit: 30 ohm;
The power default value of renal artery radiofrequency ablation instrument is 8W, degree of regulation ± 0.2W; Temperature implied value is 41 ° of C, degree of regulation ± 1 ° C; It is 400 ohm that the limit default value is cut off in impedance; The time default value of melting is 60 seconds, and 1-150 is adjustable second.The renal artery radiofrequency ablation instrument can show that the variation of impedance and record impedance reduce ratio.
2, perfusion of saline pump
The perfusion of saline flow rate pump adjusting range that adopts: 5-50ml/min, default value is: 10ml/min, low flow velocity adjusting range: 1-5ml/min, default value is: 2ml/min.
3, surgical object is chosen the adult boar through castrating, weight 45kg-60kg, and renal artery blood vessel minimum dimension is diameter 3.5mm, length 15mm.This exemplary procedure is chosen the adult boar of 45kg castrating.
4, renal artery ablative surgery
Under x-ray fluoroscopy, pigtail catheter is delivered to descending aorta near renal artery along seal wire.Injection nitroglycerin before the angiography.According to the arteriorenal diameter of contrast agent qualitative assessment of injection and length to determine suitable radio-frequency (RF) ablation point.Withdraw from pigtail catheter, send into guiding catheter and guiding catheter is sent in the renal artery along seal wire, withdraw from seal wire.
Select suitable renal artery ablation catheter by arteriorenal size and length, selection principle is:
Renal artery diameter 3.5mm-4.5mm selects the crooked curved conductor in distal end of catheter 6mm place;
Renal artery diameter 4.5mm-6mm selects the crooked curved conductor in distal end of catheter 9mm place;
The renal artery diameter is selected the crooked curved conductor in distal end of catheter 12mm place greater than 6mm.
Renal artery length 15mm-19mm or surpass 30mm selects 120 ° or 60 °, and capable 3 or 6 of control handle melts;
Renal artery length 25mm-29mm selects 72 °, and capable 5 of control handle melts;
Renal artery length 10mm-14mm or 20mm-24mm select 180 ° or 90 °, and capable 2 or 4 of control handle melts.
Renal artery radiofrequency ablation controllable electrodes conduit is connected with the perfusion of saline pump with the renal artery radiofrequency ablation instrument, starting the perfusion of saline pump pours at a high speed with 10ml/min speed, until the air in the conduit is all discharged, again the perfusion of saline pump is transferred to the low speed perfusion of 2ml/min.Keep low speed perfusion and renal artery ablation catheter far-end straight configuration, through the guiding catheter intracavity renal artery radiofrequency ablation controllable electrodes conduit is sent in the renal artery, under x-ray fluoroscopy ablating electrode is sent to the position that the renal artery distal-most end meets the condition of melting, the position that meets the condition of melting is blood vessel diameter 〉=3.5mm.Pulling hands pulls and regulates the bending of catheter tube far-end ablating electrode is clinged on the renal artery wall, whether observe impedance suitable, starting the renal artery radiofrequency ablation instrument melts, ablation parameter is set is: power 8W, time 45S, perfusion of saline pump discharge 10ml/min, 41 ℃ of ablating electrode temperature, monitoring electrode setting temperature 50 C, observe and record the variation of power, temperature, impedance in the ablation procedure, parasympathetic tissue temperature (temperature P) reaches setting value and cuts off immediately the renal artery radiofrequency ablation instrument, adjusts the catheter tube position, descends a bit to melt.
Finish first melt after, adjust the catheter tube position, pulling hands pulls to replying position adjustments catheter tube far-end and stretches, conduit is withdrawn a 3mm sounding mark, operator's left hand is held the holder handle, and the right hand rotates an angle clockwise with rotating handle, pulls hands again and pulls and regulate the catheter proximal end bending ablating electrode is clinged on the renal artery wall, repeat above-mentioned ablation procedure, carry out second point and melt.Repeat above process until finish the whole piece renal artery and melt.
5, result
After operation finishes, sew up the femoral artery puncture mouth, operative incision also need be sewed up.Experimental subject (boar) injection overtreatment is pacified dead liquid or potassium chloride IV solution is implemented euthanasia to animal.After the euthanasia, collect the renal artery of laboratory animal, after the renal artery length direction is cut renal artery open, observe, can see damage and be helical form, as shown in Figure 8, be cut into some lamellars along arteriorenal cross section, can see the complete circle tubular burn that girth is 12mm-24mm at the renal artery inwall.
Electrode of the present utility model arranges in groups, and every group includes ablating electrode and monitoring electrode, and the catheter tube far-end can be provided with electrode more than 1 group along axis.Present embodiment is 1 group, an ablating electrode and a monitoring electrode catheter.Do not have fill orifice on the ablating electrode, the monitoring electrode is ring-type, the adjacent ablating electrode through the interval, the temperature of monitoring distance ablating electrode 0.5-2.5mm place parasympathetic tissue, thereby the temperature of monitoring ablation areas.Each monitoring electrode interior is equipped with occasionally critesistor of temperature element thermoelectricity, and the temperature of the parasympathetic tissue that monitoring is melted in ablation procedure reaches the clinical treatment required value with judgement; determine to melt terminal point; effectively melt guaranteeing, and reduce damage to blood vessel, protected blood vessel.The conduit that has overcome prior art only can be measured the temperature of ablating electrode, and this temperature is the temperature at ablation areas center, rather than the temperature of zone of ablation edge tissues, can not monitor the defective of the size of ablation areas.The monitoring electrode also can link to each other with the electrophysiology instrument device, the conduction of monitoring sympathetic signal, and sympathetic nerve conduction waveform before and after contrast is melted, whether auxiliary judgment operation terminal point is finished, and this utility model has solved the problem of the conduit clinical operation endless of prior art.Behind the radiofrequency ablation of clinically arrhythmia extensive use of prior art, there is about 20% relapse rate, abnormal conduction does not thoroughly interrupt, structure of the present utility model also can be used for the heart radio frequency ablation art, monitoring zone of ablation tissue temperature, thoroughly interrupt cardiac electrical abnormal conduction, guarantee to melt effectively, greatly reduce relapse rate.
Claims (10)
1. a renal artery radiofrequency ablation controllable electrodes conduit is provided with catheter tube (3), and the far-end of catheter tube (3) is connected with electrode, and near-end is connected with control handle (4), it is characterized in that: described electrode is ablating electrode (1) and monitoring electrode (2).
2. renal artery radiofrequency ablation controllable electrodes conduit according to claim 1, it is characterized in that: described ablating electrode (1) and monitoring electrode (2) are arranged on far-end along the axis setting of catheter tube (3), are provided with interval (19) between ablating electrode (1) and the monitoring electrode (2).
3. renal artery radiofrequency ablation controllable electrodes conduit according to claim 2, it is characterized in that: described ablating electrode (1) adopts platinumiridio hollow bar or pipe (12), distal end is circular shape (13), has cold brine perfusion hole (14) on the ablating electrode (1).
4. renal artery radiofrequency ablation controllable electrodes conduit according to claim 3, it is characterized in that: described ablating electrode (1) external diameter 1mm-2.67mm, long 1mm-4mm, cold brine perfusion hole (14) is 1-20, the aperture is 0.1mm-0.4mm, is distributed on the distal end and tube wall of ablating electrode (1).
5. renal artery radiofrequency ablation controllable electrodes conduit according to claim 2 is characterized in that: described monitoring electrode (2) is ring-type, external diameter 1mm-2.67mm, long 0.4mm-1mm.
6. renal artery radiofrequency ablation controllable electrodes conduit according to claim 5 is characterized in that: temperature element (16) is housed in the described monitoring electrode (2).
7. renal artery radiofrequency ablation controllable electrodes conduit according to claim 6 is characterized in that: described temperature element (16) is arranged in monitoring electrode (2) ring in vertically the groove (17).
8. renal artery radiofrequency ablation controllable electrodes conduit according to claim 2 is characterized in that: described interval (19) are 0.2mm-2mm.
9. according to claim 3,5,6 or 8 described renal artery radiofrequency ablation controllable electrodes conduits, it is characterized in that: described ablating electrode (1) external diameter 1.25mm, long 1.6mm, have 9 cold brine perfusion holes (14) on the ablating electrode (1), wherein 3 cold brine perfusion holes are evenly distributed on electrode tip, and 6 cold brine perfusion holes are evenly distributed on the tube wall at ablating electrode middle part; Described monitoring electrode (2) external diameter 1.33mm, long 0.6mm; Described temperature element is thermocouple; Described interval (19) is 0.5mm.
10. renal artery radiofrequency ablation controllable electrodes conduit according to claim 1, it is characterized in that: described control handle (4) is regulated the bending of catheter guide tube body (3) far-end 6mm-75mm place or is stretched, rotation to 120 ° or 60 °, 72 °, 180 ° or 90 ° of positions.
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| CN 201220348382 CN202776541U (en) | 2012-07-18 | 2012-07-18 | Controllable renal artery radiofrequency ablation electrode conduit |
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| CN 201220348382 CN202776541U (en) | 2012-07-18 | 2012-07-18 | Controllable renal artery radiofrequency ablation electrode conduit |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016161209A1 (en) * | 2015-03-31 | 2016-10-06 | St. Jude Medical, Cardiology Division, Inc. | Methods and devices for delivering pulsed rf energy during catheter ablation |
| CN106572881A (en) * | 2014-02-04 | 2017-04-19 | 波士顿科学国际有限公司 | Alternative placement of thermal sensors on bipolar electrode |
| US10052152B2 (en) | 2010-08-04 | 2018-08-21 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Catheter electrode assembly |
| CN112638301A (en) * | 2018-08-13 | 2021-04-09 | 悉尼大学 | Catheter ablation device with impedance monitoring |
| US11246658B2 (en) | 2016-10-04 | 2022-02-15 | St. Jude Medical, Cardiology Division, Inc. | Ablation catheter tip |
| US11839423B2 (en) | 2013-10-28 | 2023-12-12 | St. Jude Medical, Cardiology Division, Inc. | Ablation catheter designs and methods with enhanced diagnostic capabilities |
-
2012
- 2012-07-18 CN CN 201220348382 patent/CN202776541U/en not_active Expired - Lifetime
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10052152B2 (en) | 2010-08-04 | 2018-08-21 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Catheter electrode assembly |
| US11839423B2 (en) | 2013-10-28 | 2023-12-12 | St. Jude Medical, Cardiology Division, Inc. | Ablation catheter designs and methods with enhanced diagnostic capabilities |
| CN106572881A (en) * | 2014-02-04 | 2017-04-19 | 波士顿科学国际有限公司 | Alternative placement of thermal sensors on bipolar electrode |
| CN106572881B (en) * | 2014-02-04 | 2019-07-26 | 波士顿科学国际有限公司 | Substitution of the heat sensor on bipolar electrode is placed |
| WO2016161209A1 (en) * | 2015-03-31 | 2016-10-06 | St. Jude Medical, Cardiology Division, Inc. | Methods and devices for delivering pulsed rf energy during catheter ablation |
| EP3777745A1 (en) * | 2015-03-31 | 2021-02-17 | St. Jude Medical, Cardiology Division, Inc. | Methods and devices for delivering pulsed rf energy during catheter ablation |
| EP3701899B1 (en) * | 2015-03-31 | 2022-05-18 | St. Jude Medical, Cardiology Division, Inc. | Devices for delivering pulsed rf energy during catheter ablation |
| US11350986B2 (en) | 2015-03-31 | 2022-06-07 | St. Jude Medical, Cardiology Division, Inc. | High-thermal-sensitivity ablation catheters and catheter tips |
| US11419674B2 (en) | 2015-03-31 | 2022-08-23 | St. Jude Medical, Cardiology Division, Inc. | Methods and devices for delivering pulsed RF energy during catheter ablation |
| US11246658B2 (en) | 2016-10-04 | 2022-02-15 | St. Jude Medical, Cardiology Division, Inc. | Ablation catheter tip |
| CN112638301A (en) * | 2018-08-13 | 2021-04-09 | 悉尼大学 | Catheter ablation device with impedance monitoring |
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