CN202725200U - Liquid storage groove in micro-fluidic chip - Google Patents

Liquid storage groove in micro-fluidic chip Download PDF

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Publication number
CN202725200U
CN202725200U CN 201220354031 CN201220354031U CN202725200U CN 202725200 U CN202725200 U CN 202725200U CN 201220354031 CN201220354031 CN 201220354031 CN 201220354031 U CN201220354031 U CN 201220354031U CN 202725200 U CN202725200 U CN 202725200U
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CN
China
Prior art keywords
liquid storage
micro
fluidic chip
passage
rifle head
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Expired - Fee Related
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CN 201220354031
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Chinese (zh)
Inventor
孙悦
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Guangdong Pharmaceutical University
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Guangdong Pharmaceutical University
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Priority to CN 201220354031 priority Critical patent/CN202725200U/en
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Publication of CN202725200U publication Critical patent/CN202725200U/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

The utility model discloses a liquid storage groove in a micro-fluidic chip. The liquid storage groove in the micro-fluidic chip comprises a passage, wherein a liquid storage hole is arranged at the tail end of the passage, a liquid storage spearhead communicated with the passage is inserted in the liquid storage hole, and a fixing layer used to bond and fix the liquid storage spearhead is arranged at the edge of the upper end of the liquid storage hole. The liquid storage groove in the micro-fluidic chip is capable of storing organic solvents in a large volume, the position where the fixing layer is arranged, namely the bonding position between the liquid storage spearhead and the liquid storage hole, does not contact the organic solvents, so that the bonding position keeps firm for a long time, and further the need of the separation and analysis of a chip sample and the requirement of accuracy reproducibility are met. The liquid storage groove in the micro-fluidic chip is widely applied to the technical field of micro-fluidic chips.

Description

Reservoir on a kind of micro-fluidic chip
Technical field
The utility model relates to the micro-fluidic chip technology, particularly the reservoir that is used for the storage organic solvent on a kind of micro-fluidic chip.
Background technology
Micro-fluidic chip is a kind of novel analytical technology, its objective is the basic operation units such as the sample preparation of biological, chemistry, medical analysis process, reaction, separation, detection are integrated on the chip of a micro-meter scale, automatically finishes the analysis overall process.And the matrix of making micro-fluidic chip has a lot, comprises quartz, glass, PDMS, PC etc., but the micro-fluidic chip take glass as matrix is still and is most widely used.Reservoir is the indispensable parts on the micro-fluidic chip in addition.
At present, reservoir on the micro-fluidic chip take glass as matrix, its form comprises two kinds: the first, end spiles in the microchannel, then be that 4mm and height are that the micropipette tube head of 6mm is on this aperture at chip upper surface with the epoxy resin bonding diameter, and then formation reservoir, although this reservoir, it can store more organic solvent, satisfy the quantity of solvent demand of sample treatment or analysis, but epoxy resin can be in organic solvent swelling, even be partly dissolved, therefore this reservoir and be not suitable for being loaded with the machine solvent; The second, with punching of being bored on glass as reservoir, but this reservoir, its capacity is too small, solvent is very soon evaporation therein, and especially therefore some volatile organic solvent can not satisfy repeatedly sample introduction when doing chip electrophoresis analysis experiment, need constantly to replenish to add solvent, so not only make the reappearance variation of the numerous and diverse but also analysis result of operation sequence.
The utility model content
In order to solve the problems of the technologies described above, the reservoir on the micro-fluidic chip that the purpose of this utility model provides and a kind ofly is easy to realize, simple in structure and capacity is larger.
The technical scheme that the utility model adopts is: the reservoir on a kind of micro-fluidic chip, it comprises passage, the end of described passage is provided with liquid storage hole, is inserted with the liquid storage rifle head with channel connection in liquid storage hole, is provided with at the edge of liquid storage hole upper end for the fixing fixed bed of liquid storage rifle head of bonding.
Further, the lower end of described liquid storage rifle head flushes with the top edge of passage.
Further, the lower end of described liquid storage rifle head is provided with breach.
Further, the outer surface of described liquid storage rifle head is provided with protective layer.
Further, described protective layer is silicone protective layer or rubber cover.
Further, described fixed bed is the blob of viscose fixed bed.
The beneficial effects of the utility model are: the utility model not only can be preserved organic solvent in large volume ground, and the position of fixed bed setting, it is the bonding part between liquid storage rifle head and the liquid storage hole, it can organic solvent exposure, therefore this bonding part can keep firmly for a long time, and then satisfies the needs of chip sample compartment analysis and satisfy the reproducible requirement of precision.
Description of drawings
Below in conjunction with accompanying drawing the specific embodiment of the present utility model is described further:
Fig. 1 is the structural representation of the reservoir on a kind of micro-fluidic chip of the utility model.
The specific embodiment
By shown in Figure 1, reservoir on a kind of micro-fluidic chip, it comprises passage 4, the end of described passage 4 is provided with liquid storage hole, in liquid storage hole, be inserted with the liquid storage rifle head 1 that is communicated with passage 4, be provided with the fixed bed 2 for bonding liquid storage rifle head 1 at the edge of liquid storage hole upper end.Described liquid storage rifle head 1 and liquid storage hole close contact.Described fixed bed 2 is the blob of viscose fixed bed, but described fixed bed 2 is not only for this type.
Can get according to above-mentioned the utility model, the utility model not only can be preserved organic solvent in large volume ground, at least can store the organic solvent of 70 μ l, and the position of fixed bed 2 settings, it is the bonding part between liquid storage rifle head and the liquid storage hole, it can not touch organic solvent, thereby this bonding part can keep firm for a long time.Therefore the utility model can satisfy the storage volatile organic solvent, and can be used in the electrophoresis experiment of common cross chip, and is reusable more than six times, satisfies the reproducible requirement of precision.
Be further used as preferred embodiment, the lower end of described liquid storage rifle head 1 flushes with the top edge of passage 4.Namely when liquid storage hole inserts the liquid storage rifle head 1 be communicated with passage 4, described liquid storage rifle head 1 not only with the liquid storage hole close contact, and the lower end of liquid storage rifle head 1 flushes with the top edge of passage 4.
Be further used as preferred embodiment, the lower end of described liquid storage rifle head 1 is provided with breach 3.Described breach 3 is v-notch, and it can guarantee the permeability of passage 4.
Be further used as preferred embodiment, the outer surface of described liquid storage rifle head 1 is provided with protective layer.Described protective layer, it not only plays the effect of protection liquid storage rifle head 1, and liquid storage rifle head 1 and liquid storage hole are close to more.
Be further used as preferred embodiment, described protective layer is silicone protective layer or rubber cover, but not only for the protective layer of this two type.
The utility model is on the micro-fluidic chip that acts on take glass as matrix, and the micro-fluidic chip take glass as matrix preparation method of the present utility model as:
The first step is beaten liquid storage hole at the end of passage 4, will in time wash away the glass disintegrating slag when beating liquid storage hole, guarantees that as far as possible the edge of liquid storage hole is round and smooth indefectible, and described passage 4 is originally to have had on the micro-fluidic chip take glass as matrix;
Second step, the thin segment rifle head of excision liquid-transfering gun forms breach 3 as liquid storage rifle head 1 and the fritter that cuts away V-type in the lower end of liquid storage rifle head 1;
The 3rd step, with liquid storage rifle head 1 complete closely the insertion in the liquid storage hole, guarantee that simultaneously the lower end of liquid storage rifle head 1 flushes with the top edge of passage 4, and breach 3 aligns with the outlet of passage 4, and then the permeability of assurance chip channel;
The 4th step, detect whether leakage of reservoir, if leakage then again make other liquid storage rifle head 1 and insert in the liquid storage hole, otherwise, then carry out next step operation;
The 5th step, cut one section silicone tube or rubber tube as protective layer, its length is about about half centimetre, the lower end that as far as possible guarantees silicone tube or rubber tube is smooth, then gently press silicone tube or rubber tube, when itself and liquid storage hole are close to and liquid storage rifle head 1 be close to, make like this liquid storage rifle head 1 more can be fixed in the liquid storage hole, and play the effect of protection liquid storage rifle head 1;
In the 6th step, adopt the blob of viscose fixed bed as fixed bed 2, and with its edge that is arranged on the liquid storage hole upper end, make its bonding protective layer, and then play the fixedly effect of liquid storage rifle head 1 of bonding.
Therefore got by above-mentioned, in the preparation of the micro-fluidic chip take glass as matrix method of the present utility model, the material of implementation step and employing is all very simple, so the utility model not only is easy to realize but also cost is low.
More than be that better enforcement of the present utility model is specified, but the utility model is created and is not limited to described embodiment, those of ordinary skill in the art make all equivalent variations or replacement also can doing under the prerequisite of the utility model spirit, the distortion that these are equal to or replace all is included in the application's claim limited range.

Claims (6)

1. the reservoir on the micro-fluidic chip, it is characterized in that: it comprises passage (4), the end of described passage (4) is provided with liquid storage hole, in liquid storage hole, be inserted with the liquid storage rifle head (1) that is communicated with passage (4), be provided with for the fixedly fixed bed (2) of liquid storage rifle head (1) that bonds at the edge of liquid storage hole upper end.
2. the reservoir on described a kind of micro-fluidic chip according to claim 1, it is characterized in that: the lower end of described liquid storage rifle head (1) flushes with the top edge of passage (4).
3. the reservoir on described a kind of micro-fluidic chip according to claim 1, it is characterized in that: the lower end of described liquid storage rifle head (1) is provided with breach (3).
4. according to claim 1 and 2 or the reservoir on 3 described a kind of micro-fluidic chips, it is characterized in that: the outer surface of described liquid storage rifle head (1) is provided with protective layer.
5. the reservoir on described a kind of micro-fluidic chip according to claim 4, it is characterized in that: described protective layer is silicone protective layer or rubber cover.
6. the reservoir on described a kind of micro-fluidic chip according to claim 1, it is characterized in that: described fixed bed (2) is the blob of viscose fixed bed.
CN 201220354031 2012-07-20 2012-07-20 Liquid storage groove in micro-fluidic chip Expired - Fee Related CN202725200U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201220354031 CN202725200U (en) 2012-07-20 2012-07-20 Liquid storage groove in micro-fluidic chip

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 201220354031 CN202725200U (en) 2012-07-20 2012-07-20 Liquid storage groove in micro-fluidic chip

Publications (1)

Publication Number Publication Date
CN202725200U true CN202725200U (en) 2013-02-13

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103252263A (en) * 2013-05-27 2013-08-21 苏州扬清芯片科技有限公司 Self-luminescence type micro-fluidic chip

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103252263A (en) * 2013-05-27 2013-08-21 苏州扬清芯片科技有限公司 Self-luminescence type micro-fluidic chip

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GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20130213

Termination date: 20130720