CN202715360U - Stirring type dialysis device - Google Patents
Stirring type dialysis device Download PDFInfo
- Publication number
- CN202715360U CN202715360U CN 201220247263 CN201220247263U CN202715360U CN 202715360 U CN202715360 U CN 202715360U CN 201220247263 CN201220247263 CN 201220247263 CN 201220247263 U CN201220247263 U CN 201220247263U CN 202715360 U CN202715360 U CN 202715360U
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- dialysis
- movable disc
- stirring
- cylinder body
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Abstract
The utility model relates to the field of dialysis devices, and particularly discloses a stirring type dialysis device, which comprises a dialysis cylinder, a movable disk, a stir bar and a stirrer, wherein the dialysis cylinder comprises a cylinder body, a cylinder cover, a liquid inlet valve, a liquid outlet valve and 4-10 support rods; the cylinder cover is buckled with the cylinder body; the liquid inlet valve is positioned on the upper side of the cylinder body; the liquid outlet valve is positioned on the lower side of the cylinder body; one end of each support rod is vertically connected to the bottom of the cylinder body; the 4-10 support rods are uniformly distributed in the form of a circular array; the movable disk is arranged in the circular array of the support rods; the upper surface of the movable disk is parallel to the horizontal plane; the stir bar is positioned on the upper surface of the movable disk; and the stirrer is positioned at a position below the dialysis cylinder which corresponds to the movable disk. The stirring type dialysis device disclosed by the utility model is easy to operate, has high dialysis efficiency, can be used for protecting samples from being polluted in an operating process, and is suitable for dialysis operation of a production level.
Description
Technical field
The utility model relates to dialysis apparatus, specifically discloses a kind of stirring-type dialysis apparatus.
Background technology
Dialysis is one of the easiest separating and purifying technology commonly used in Biochemistry Experiment chamber, in the preparation process of large biological molecule, is used for desalination, removes a small amount of organic solvent, removes biological micromolecule impurity and concentrating sample etc.Dialysis is normally made pellicle bag-shaped, the large biological molecule sample solution is inserted in the bag, this bag filter is immersed in water or the buffer solution, the large biological molecule of the macromolecule in the sample solution is trapped within the bag, and the continuous diffusion dialysis of salt and small-molecule substance is outside bag, until the concentration on the inside and outside both sides of bag reaches balance.
The power of dialysis is that diffusion is pressed, and is formed by the concentration gradient of both sides inside and outside the transmembrane.Diffusion is pressed and is impelled salt and small-molecule substance by the low concentration region of the continuous diffusion dialysis of the high concentration region of bag filter inside outside bag, thereby makes the concentration balance of bag inside and outside both sides.In existing other dialysis procedure of production level, because the dialysis sample size is large, dialysis time is long, the inhomogeneous phenomenon of sample concentration in dislysate and the bag filter often can occur, reduces dialytic efficiency, therefore, often manually put upside down bag filter and carry out mixing.But manually put upside down the operation of bag filter, not only waste time and energy, but also may introduce unnecessary pollution, the quality of impact dialysis product.
In order to improve dialytic efficiency, can improve dialysis apparatus, obtain the novel dialytic device that dialytic efficiency is high, dialysis-effect is good.
The utility model content
The purpose of this utility model is to overcome the defective of prior art, and a kind of stirring-type dialysis apparatus is provided.
The technical solution of the utility model is: a kind of stirring-type dialysis apparatus, comprise dialysis cylinder, movable disc, stirrer and agitator, and described dialysis cylinder comprises gray iron, liquid feed valve, liquid valve, 4～10 support bars; Described cylinder cap and described cylinder body fasten, and described liquid feed valve is positioned at described cylinder body upside, and described liquid valve is positioned at described cylinder body downside, and an end of described support bar is vertically connected at described cylinder base, and described 4～10 support bars are evenly arranged by circular array; Be provided with described movable disc in the described support bar circular array, and the upper surface of described movable disc is parallel with horizontal plane; Described stirrer is positioned at described movable disc upper surface; Described agitator is positioned at the position of described dialysis cylinder below, corresponding described movable disc.
The employed stirrer of the utility model and agitator can be magnetic stir bar and the magnetic stirring apparatus of routine, by rotation and the rotating speed of agitator control stirrer.The upper surface of movable disc can guarantee stirrer parallel with horizontal plane rotates at the body surface of level.
When stirring-type dialysis apparatus of the present utility model uses, movable disc is put into the bottom of bag filter sealing, in bag filter, poured into sample and place stirrer at the movable disc upper surface, tie the bag filter other end; Bag filter is embedded in the circular array that many (4～10) support bars of dialysis cylinder consist of, fix bag filter, the upper surface level of movable disc covers cylinder cap; Dislysate is poured into cylinder body by liquid feed valve, filled with liquid after, open agitator, make stirrer stirred sample solution under the control of agitator, prevent that the long-time dialysis of sample from causing inhomogeneous, emit liquid in the dialysis cylinder from liquid valve after dialysis finishes.If dialysis finishes then shut-down operation, take out bag filter; If still need continue dialysis, then again pour into new dislysate from liquid feed valve.
More excellent, described stirring-type dialysis apparatus can also comprise peristaltic pump and connecting device, the two ends of described peristaltic pump respectively by connecting device and described liquid feed valve be connected liquid valve and be connected.
When using peristaltic pump, the using method of stirring-type dialysis apparatus of the present utility model is as follows: the bottom of movable disc being put into the bag filter sealing, in bag filter, pour into sample and place stirrer at the movable disc upper surface, tie the bag filter other end, bag filter is embedded in the circular array of many (4～10) support bars formations, keep bag filter to be in erectility, the upper surface level of movable disc covers cylinder cap; Pour into dislysate by liquid feed valve, then peristaltic pump and liquid feed valve and liquid valve are connected by connecting device, start peristaltic pump with the mixing dislysate; Open agitator, make stirrer stirred sample solution under the control of agitator, prevent that the long-time dialysis of sample from causing inhomogeneous.
More excellent, it is central that described support bar circular array is positioned at described cylinder body.
One end of support bar of the present utility model vertically is fixed in described cylinder base, other parts are vertically pointed to the cylinder body opening part, therefore 4～10 support bars one rounded array arrangement of cylinder body central authorities that coexists has surrounded a virtual tubular cavity, is used for placing bag filter to be dialysed.
More excellent, described movable disc be uncovered down, without the hollow circular cylinder of bottom surface.
More excellent, described movable disc has certain thickness, and its lower surface central authorities are provided with arc-shaped recess.
Because existing bag filter mostly is the uncovered type of an end or open at both ends type, when using both ends open type bag filter, the bottom of bag filter need to be tied first; Therefore bag filter ties rear out-of-flatness, in order to guarantee the level of movable disc upper surface, makes the stirrer normal rotation, the irregular bag place of pricking need to be positioned in the arc-shaped recess below the movable disc, perhaps puts into the inside of movable disc hollow.
More excellent, described stirrer, described movable disc center, described support bar circular array center and described agitator are centered close on the same straight line.
More excellent, described cylinder cap lower surface central authorities are provided with fixture.
Optimum, described fixture is clip, annulus or hook.The bag filter upper end that can clamping when fixture is clip hitches, when be annulus, the bag filter upper end that can hitch tie up to the annulus place, and when being hook, the hook front end is more blunt, can catch on the bag filter that hitches.Bag filter is suitable for reading can a little upwards mention after tying, and the upper end is hung on the fixture of cylinder cap, then puts down cylinder cap and buckles well, thereby make bag filter be in erectility, better dialyses.
Movable disc of the present utility model and four are strong can be made by rigidity, transparent and inert material, such as the transparent polymer material such as polystyrene or similar glass material etc.
Stirring-type dialysis apparatus of the present utility model can constantly stir the liquid in the bag filter in dialysis, to avoid the occurring sample concentration non-uniform phenomenon in the bag filter, thereby avoiding manually getting involved puts upside down bag filter, simplified the dialysis operation, save dialysis time, avoided the sample contamination in the operating process, be fit to produce other dialysis operation of level, improve product quality and production efficiency.
Description of drawings
Fig. 1: a kind of stirring-type dialysis apparatus structural representation (1. dialysis cylinder 2. movable disc 3. stirrers 4. agitators 11. cylinder bodies 12. cylinder caps 13. liquid feed valves 14. liquid valves 15. support bars)
Fig. 2: a kind of stirring-type dialysis apparatus structural representation (1. dialysis cylinder 2. movable disc 3. stirrers 4. agitators 11. cylinder bodies 12. cylinder caps 13. liquid feed valves 14. liquid valves 15. support bars 16. peristaltic pumps 17. connecting devices)
Fig. 3: movable disc rip cutting schematic diagram (2. movable disc 21. depressions)
Fig. 4: cylinder cover structure schematic diagram (12. cylinder caps, 121. fixtures)
The specific embodiment
The following specific embodiment only is used for illustrating the utility model, but does not limit protection domain of the present utility model.
A kind of stirring-type dialysis apparatus as shown in Figure 1 comprises dialysis cylinder 1, movable disc 2, stirrer 3 and agitator 4, and dialysis cylinder 1 comprises cylinder body 11, cylinder cap 12, liquid feed valve 13, liquid valve 14, four support bars 15; Cylinder cap 12 fastens with cylinder body 11, and liquid feed valve 13 is positioned at cylinder body 11 upsides, and liquid valve 14 is positioned at cylinder body 11 downsides, and an end of support bar 15 is vertically connected at cylinder body 11 bottoms, and four support bars 15 are evenly arranged by circular array; Be provided with movable disc 2 in support bar 15 circular array, and the upper surface of movable disc 2 is parallel with horizontal plane; Stirrer 3 is positioned at movable disc 2 upper surfaces; Agitator 4 is positioned at the position of dialysis cylinder 1 below, corresponding movable disc 2.
During use, the bag filter bottom lock is put into the bag filter bottom with movable disc 2, pours into sample and places stirrer 3 at movable disc 2 upper surfaces in bag filter, ties the bag filter other end; Bag filter is embedded in the circular array of dialysis cylinder 1 interior many (4) support bar 15 formations, fix bag filter, the upper surface level of movable disc 2 covers cylinder cap 12; Dislysate is poured into cylinder body 11 by liquid feed valve 13, after having filled with liquid, open agitator 4, make stirrer 3 stirred sample solution under the control of agitator 4, prevent that the long-time dialysis of sample from causing inhomogeneous, emit liquid in the dialysis cylinder from liquid valve 14 after dialysis finishes.If dialysis finishes then shut-down operation, take out bag filter; If still need continue dialysis, then again pour into new dislysate from liquid feed valve 13.
A kind of stirring-type dialysis apparatus of the present utility model can also comprise dialysis cylinder 1, movable disc 2, stirrer 3 and agitator 4 as shown in Figure 2, and dialysis cylinder 1 comprises cylinder body 11, cylinder cap 12, liquid feed valve 13, liquid valve 14, six roots of sensation support bar 15; Cylinder cap 12 fastens with cylinder body 11, and liquid feed valve 13 is positioned at cylinder body 11 upsides, and liquid valve 14 is positioned at cylinder body 11 downsides, and an end of support bar 15 is vertically connected at cylinder body 11 bottoms, and six roots of sensation support bar 15 is evenly arranged by circular array; Be provided with movable disc 2 in support bar 15 circular array, and the upper surface of movable disc 2 is parallel with horizontal plane; Stirrer 3 is positioned at movable disc 2 upper surfaces; Agitator 4 is positioned at the position of dialysis cylinder 1 below, corresponding movable disc 2.Dialysis apparatus of the present utility model also comprises peristaltic pump 16 and connecting device 17, is connected with liquid valve by connecting device 17 and liquid feed valve 13 respectively and is connected in the two ends of peristaltic pump 16; Movable disc 2 has certain thickness, and its lower surface central authorities are provided with arc-shaped recess 21(and see Fig. 3); Cylinder cap 12 lower surface central authorities are provided with fixture 121(Fig. 4).The center of stirrer 3, movable disc 2, support bar 15 circular array center and agitator 4 be centered close on the same straight line.
Because disk 2 has certain thickness, its lower surface central authorities are provided with arc-shaped recess 21, therefore can adopt the bag filter of open at both ends.During use, first bag filter one end is tied, then movable disc 2 is put into the bottom that bag filter ties, and tying of bag filter held arc-shaped recess 21 places that put into movable disc 2, make the upper surface level of movable disc 2; In bag filter, pour into sample and place stirrer 3 at movable disc 2 upper surfaces, tie the bag filter other end, bag filter is embedded in the circular array of many (6) support bars 15, the bag filter upper end is fixed on the fixture 121 of cylinder cap 12 lower surface central authorities, make bag filter be in erectility, fastening cylinder cap 12; Pour into dislysate by liquid feed valve 13, then peristaltic pump 16 and liquid feed valve 13 and liquid valve 14 are connected by connecting device 17, start peristaltic pump 16 with the mixing dislysate; Open agitator 4, make stirrer 3 stirred sample solution under the control of agitator 4, prevent that the long-time dialysis of sample from causing inhomogeneous.
Stirring-type dialysis apparatus of the present utility model can constantly stir the liquid in the bag filter in dialysis, to avoid the occurring sample concentration non-uniform phenomenon in the bag filter, thereby avoiding manually getting involved puts upside down bag filter, simplified the dialysis operation, save dialysis time, avoided the sample contamination in the operating process, be fit to produce other dialysis operation of level, improve product quality and production efficiency.
Claims (8)
1. a stirring-type dialysis apparatus is characterized in that, comprises dialysis cylinder, movable disc, stirrer and agitator, and described dialysis cylinder comprises gray iron, liquid feed valve, liquid valve, 4～10 support bars; Described cylinder cap and described cylinder body fasten, and described liquid feed valve is positioned at described cylinder body upside, and described liquid valve is positioned at described cylinder body downside, and an end of described support bar is vertically connected at described cylinder base, and described 4～10 support bars are evenly arranged by circular array; Be provided with described movable disc in the described support bar circular array, and the upper surface of described movable disc is parallel with horizontal plane; Described stirrer is positioned at described movable disc upper surface; Described agitator is positioned at the position of described dialysis cylinder below, corresponding described movable disc.
2. stirring-type dialysis apparatus as claimed in claim 1 is characterized in that, described stirring-type dialysis apparatus can also comprise peristaltic pump and connecting device, the two ends of described peristaltic pump respectively by connecting device and described liquid feed valve be connected liquid valve and be connected.
3. stirring-type dialysis apparatus as claimed in claim 1 is characterized in that, it is central that described support bar circular array is positioned at described cylinder body.
4. stirring-type dialysis apparatus as claimed in claim 1 is characterized in that, described movable disc be uncovered down, without the hollow circular cylinder of bottom surface.
5. stirring-type dialysis apparatus as claimed in claim 1 is characterized in that, described movable disc has certain thickness, and its lower surface central authorities are provided with arc-shaped recess.
6. stirring-type dialysis apparatus as claimed in claim 1 is characterized in that, described stirrer, described movable disc center, described support bar circular array center and described agitator are centered close on the same straight line.
7. stirring-type dialysis apparatus as claimed in claim 1 is characterized in that, described cylinder cap lower surface is provided with fixture.
8. stirring-type dialysis apparatus as claimed in claim 7 is characterized in that, described fixture is clip, annulus or hook.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220247263 CN202715360U (en) | 2012-05-29 | 2012-05-29 | Stirring type dialysis device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220247263 CN202715360U (en) | 2012-05-29 | 2012-05-29 | Stirring type dialysis device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202715360U true CN202715360U (en) | 2013-02-06 |
Family
ID=47617200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201220247263 Expired - Lifetime CN202715360U (en) | 2012-05-29 | 2012-05-29 | Stirring type dialysis device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202715360U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103657417A (en) * | 2013-11-30 | 2014-03-26 | 成都欣华源科技有限责任公司 | Dialysis device |
| CN107812262A (en) * | 2017-09-23 | 2018-03-20 | 南京律智诚专利技术开发有限公司 | A kind of automatic dialysis apparatus |
| CN108144325A (en) * | 2018-02-06 | 2018-06-12 | 江苏诺普乐生物科技有限公司 | A kind of stirring extractor, animal byproduct separating extraction device and method |
-
2012
- 2012-05-29 CN CN 201220247263 patent/CN202715360U/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103657417A (en) * | 2013-11-30 | 2014-03-26 | 成都欣华源科技有限责任公司 | Dialysis device |
| CN107812262A (en) * | 2017-09-23 | 2018-03-20 | 南京律智诚专利技术开发有限公司 | A kind of automatic dialysis apparatus |
| CN108144325A (en) * | 2018-02-06 | 2018-06-12 | 江苏诺普乐生物科技有限公司 | A kind of stirring extractor, animal byproduct separating extraction device and method |
| CN108144325B (en) * | 2018-02-06 | 2023-12-05 | 江苏诺普乐生物科技有限公司 | Stirring extraction tank, animal byproduct separation and extraction device and method |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20130206 |
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| CX01 | Expiry of patent term |