CN103657417A - Dialysis device - Google Patents
Dialysis device Download PDFInfo
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- CN103657417A CN103657417A CN201310622011.9A CN201310622011A CN103657417A CN 103657417 A CN103657417 A CN 103657417A CN 201310622011 A CN201310622011 A CN 201310622011A CN 103657417 A CN103657417 A CN 103657417A
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- pillar
- bag filter
- dialysis
- bindiny mechanism
- crossbeam
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Abstract
The invention provides a dialysis device. A fixed frame is arranged on the edge of an objective table of a magnetic stirrer, the fixed frame comprises a pillar and a cross beam, the cross beam is fixedly connected with the pillar through a screw support capable of moving along the pillar up and down, and the height of the cross beam is adjusted through adjustment of the position of the screw support on the pillar, so that positions of connecting mechanisms and dialysis bag clips are further adjusted, the position of a dialysis bag in a dialysis buffer solution is adjusted, and different experimental requirements can be met.
Description
Technical field
the present invention relates to Bioexperiment assistive device, a kind of device for dialysing being specifically related to.
Background technology
In the preparation process of large biological molecule, often utilize dialysis to remove salt, organic solvent, the biological micromolecule impurity in sample.The bag filter using in dialysis procedure be by special-purpose pellicle per sample solution amount be folded into bag-shapedly accordingly, make with clip clamping at sack place.During dialysis, first large biological molecule sample solution is inserted in bag, then with immersing in water or buffer solution after clip clamping sack, the large biological molecule of the macromolecule in sample solution is trapped within bag, and the materials such as salt and little molecule constantly diffusion dialysis outside bag, until the concentration on the inside and outside both sides of bag reaches balance.
During dialysis, in order to accelerate dialysis speed, except repeatedly changing dislysate, also can use magneton to stir.But the clip using at present only comprises two intermediate plates and three parts of axle that are connected two intermediate plates, wherein, the other end of intermediate plate is provided with groove and the elastic projection that can be fastened and connected, after this clip clips on bag filter owing to not having buoyancy member can directly sink to bag filter the bottom of water or buffer solution, cause when dialysis, cannot use the mode of magnetic force rotor (the being designated hereinafter simply as magneton) stirring that can accelerate dialysis speed.
Application number is 201220436455.4 patent of invention, a kind of bag filter buoyancy folder that is provided with foam block is provided, can allow bag filter floating, but it is exposed on dialysis buffer liquid to cause part that the bag filter of dislysate is housed, and with the buoyancy folder of foam block, be difficult to carry out disinfection by thermophilic digestion etc., inapplicable for aseptic experiment of having relatively high expectations without RNA enzyme etc.
Summary of the invention
For addressing the above problem, the invention provides a kind of adjustable dialysis bag at the medium-altitude dialysis apparatus of dislysate, adopt following technical scheme:
A dialysis apparatus, comprises magnetic stirring apparatus, reaction vessel, bag filter and bag filter clip, and reaction vessel is placed on the articles holding table of magnetic stirring apparatus, and reaction container bottom is equipped with stirrer, it is characterized in that, one end of described bag filter clip arranges circular hole; The articles holding table edge of described magnetic stirring apparatus arranges fixed mount, and described fixed mount comprises pillar and crossbeam, and described crossbeam is fixedly connected with pillar by the screw support that can move up and down along pillar; On described crossbeam, arranging two can be along the slide mechanism of cross beam movement, and described slide mechanism is fixedly connected with one end of bindiny mechanism, and the other end of described bindiny mechanism is connected with the circular hole on bag filter clip by its hook-like assembly unit.
Further, described bindiny mechanism is the plastic material of resistance to 250 ℃ of above high temperature.
Beneficial effect of the present invention is as follows:
1. dialysis apparatus provided by the invention, articles holding table edge at magnetic stirring apparatus arranges fixed mount, described fixed mount comprises pillar and crossbeam, described crossbeam is fixedly connected with pillar by the screw support that can move up and down along pillar, position by adjustment screw support on pillar, regulates horizontal depth of beam, thus the position of further adjusting connection mechanism and bag filter clip, play and regulate the position of bag filter in dialysis buffer liquid, to meet different experiments demand.
2. dialysis apparatus provided by the invention, the other end in bindiny mechanism is connected with the circular hole on bag filter clip by its hook-like assembly unit, this kind of set-up mode facilitates the connection between bindiny mechanism and bag filter clip or takes apart, facilitates experimental implementation, saves experimental period.
3. dialysis apparatus provided by the invention, on crossbeam, arranging two can be along the slide mechanism of cross beam movement, can be by regulating the position of slide mechanism, and then regulate the distance between two dialysis clamps, to meet the needs of different experiments.
4. dialysis apparatus provided by the invention, bindiny mechanism is the plastic material of resistance to 250 ℃ of above high temperature, the assorted enzyme of RNA can be removed for 250 ℃ of above high-temperature bakings by bindiny mechanism, the bindiny mechanism's part stretching in dialysis buffer liquid can not cause the pollution of dialysis buffer liquid, can reach higher requirement of experiment.Can also on reaction vessel, add a cover, further reduce and pollute.
Accompanying drawing explanation
Fig. 1 represents structural representation of the present invention; Wherein 1 represents magnetic stirring apparatus; 21 represent pillar; 22 represent screw support; 23 represent crossbeam; 24 represent slide mechanism; 25 represent bindiny mechanism; 3 represent stirrer; 4 represent reaction vessel; 5 represent bag filter clip; 6 represent bag filter.
The specific embodiment
Below in conjunction with the specific embodiment, further set forth the present invention, but be not used in, limit the scope of the invention.
As shown in Figure 1, a kind of dialysis apparatus, comprises magnetic stirring apparatus 1, reaction vessel 4, bag filter 6 and bag filter clip 5, reaction vessel 4 is placed on the articles holding table of magnetic stirring apparatus 1, reaction vessel 4 bottoms are equipped with stirrer 3, it is characterized in that, one end of described bag filter clip 5 arranges circular hole; The articles holding table edge of described magnetic stirring apparatus 1 arranges fixed mount, and described fixed mount comprises pillar 21 and crossbeam 23, and described crossbeam 23 is fixedly connected with pillar 21 by the screw support 22 that can move up and down along pillar 21; On described crossbeam, arranging two can be along the slide mechanism 24 of cross beam movement, and one end of described slide mechanism 24Yu bindiny mechanism 25 is fixedly connected with, and the other end of described bindiny mechanism 25 is connected with the circular hole on bag filter clip 5 by its hook-like assembly unit.
Dialysis apparatus according to claim 1, is characterized in that described bindiny mechanism 25 is for the plastic material of resistance to 250 ℃ of above high temperature.
Claims (2)
1. a dialysis apparatus, comprise magnetic stirring apparatus (1), reaction vessel (4), bag filter (6) and bag filter clip (5), reaction vessel (4) is placed on the articles holding table of magnetic stirring apparatus (1), reaction vessel (4) bottom is equipped with stirrer (3), it is characterized in that, one end of described bag filter clip (5) arranges circular hole; The articles holding table edge of described magnetic stirring apparatus (1) arranges fixed mount, and described fixed mount comprises pillar (21) and crossbeam (23), and described crossbeam (23) is fixedly connected with pillar (21) by the screw support (22) that can move up and down along pillar (21); On described crossbeam, arranging two can be along the slide mechanism (24) of cross beam movement, described slide mechanism (24) is fixedly connected with one end of bindiny mechanism (25), and the other end of described bindiny mechanism (25) is connected with the circular hole on bag filter clip (5) by its hook-like assembly unit.
2. dialysis apparatus according to claim 1, is characterized in that described bindiny mechanism (25) is for the plastic material of resistance to 250 ℃ of above high temperature.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310622011.9A CN103657417A (en) | 2013-11-30 | 2013-11-30 | Dialysis device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310622011.9A CN103657417A (en) | 2013-11-30 | 2013-11-30 | Dialysis device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103657417A true CN103657417A (en) | 2014-03-26 |
Family
ID=50296911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310622011.9A Pending CN103657417A (en) | 2013-11-30 | 2013-11-30 | Dialysis device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103657417A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107649005A (en) * | 2017-11-16 | 2018-02-02 | 苏州纳葛诺斯生物科技有限公司 | Immediate dialysis device |
| CN107812262A (en) * | 2017-09-23 | 2018-03-20 | 南京律智诚专利技术开发有限公司 | A kind of automatic dialysis apparatus |
| CN110616140A (en) * | 2019-10-28 | 2019-12-27 | 上海国睿生命科技有限公司 | Cell co-culture dish |
| CN113273509A (en) * | 2021-05-20 | 2021-08-20 | 宿州市草源牧业股份有限公司 | Beef cattle combing massage equipment |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3631986A (en) * | 1968-12-16 | 1972-01-04 | Rhone Poulenc Sa | Dialyzer |
| CN202415421U (en) * | 2011-12-29 | 2012-09-05 | 郑州伊美诺生物技术有限公司 | Simple dynamic protein dialysis system |
| CN202715360U (en) * | 2012-05-29 | 2013-02-06 | 上海普欣生物技术有限公司 | Stirring type dialysis device |
| CN203577642U (en) * | 2013-11-30 | 2014-05-07 | 成都欣华源科技有限责任公司 | Dialysis apparatus |
-
2013
- 2013-11-30 CN CN201310622011.9A patent/CN103657417A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3631986A (en) * | 1968-12-16 | 1972-01-04 | Rhone Poulenc Sa | Dialyzer |
| CN202415421U (en) * | 2011-12-29 | 2012-09-05 | 郑州伊美诺生物技术有限公司 | Simple dynamic protein dialysis system |
| CN202715360U (en) * | 2012-05-29 | 2013-02-06 | 上海普欣生物技术有限公司 | Stirring type dialysis device |
| CN203577642U (en) * | 2013-11-30 | 2014-05-07 | 成都欣华源科技有限责任公司 | Dialysis apparatus |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107812262A (en) * | 2017-09-23 | 2018-03-20 | 南京律智诚专利技术开发有限公司 | A kind of automatic dialysis apparatus |
| CN107649005A (en) * | 2017-11-16 | 2018-02-02 | 苏州纳葛诺斯生物科技有限公司 | Immediate dialysis device |
| CN110616140A (en) * | 2019-10-28 | 2019-12-27 | 上海国睿生命科技有限公司 | Cell co-culture dish |
| CN113273509A (en) * | 2021-05-20 | 2021-08-20 | 宿州市草源牧业股份有限公司 | Beef cattle combing massage equipment |
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Application publication date: 20140326 |