CN202638537U - Adjustable micro biological tissue grinder - Google Patents
Adjustable micro biological tissue grinder Download PDFInfo
- Publication number
- CN202638537U CN202638537U CN 201220272164 CN201220272164U CN202638537U CN 202638537 U CN202638537 U CN 202638537U CN 201220272164 CN201220272164 CN 201220272164 CN 201220272164 U CN201220272164 U CN 201220272164U CN 202638537 U CN202638537 U CN 202638537U
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- grinding rod
- shank
- biological tissue
- grinding
- adjustable micro
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Abstract
The utility model belongs to the fields of biochemistry and molecular biology, in particular relates to an adjustable micro biological tissue grinder. The adjustable micro biological tissue grinder comprises a grinding bar, a manual handle or a low-speed electric drill, wherein the grinding bar comprises a grinding bar shank, a grinding bar middle part, a grinding head and a shank groove, the grinding bar shank is of a cylindrical shape and is provided with the shank groove, the size and the shape of the shank groove are in occlusion with the manual handle or an ordinary electric drill clamping sleeve, the grinding bar middle part is of a cylindrical shape, and the grinding head is of a long cone shape or a cone shape and is matched with a normal model of a disposable centrifugal pipe in the market. The adjustable micro biological tissue grinder has the advantages of low sample consumption, high extracting efficiency and no cross contamination, the grinder is simple to operate, cost is reduced, and the working efficiency is improved.
Description
Technical field
The utility model belongs to biochemistry and biology field, particularly is widely used in the extraction field of nucleic acid and protein, is specifically related to a kind of adjustable micro-biological tissue mill.
Background technology
At present, in biochemistry and biology field, the indispensable stage the when grinding of biological tissue is preparation reactive protein or nucleic acid samples processing.Simultaneously, owing to be ground to a physical friction exothermal process, the grinding of long period very easily causes the large biological molecule vigor to descend or forfeiture.Therefore, present processing for this type of active biological sample, what common laboratory adopted is to utilize the mode that adds liquid nitrogen in mortar or the glass homogenizer to carry out hand lapping, can satisfy the experiment primary demand although do so to a certain extent, yet also there is very large defective in traditional Ginding process: (1) sample waste is large.Mortar or glass homogenizer are because its container volume is larger, and therefore a large amount of samples can be adsorbed on the grinding body inner surface in process of lapping, and this preparation for some rare biological sample of source is extremely disadvantageous; (2) poor stability.Liquid nitrogen exposes, and may damage be arranged to skin, operation palpus extreme care; (3) efficient is low.Once can only grind a kind of sample, speed is slow, and each sample grind complete after, must carry out cleaning and sterilizing to instrument, otherwise cause easily cross pollution.For the individual even more sample of hundreds of is arranged, each so operates, and too time-consuming, and many operating personnel is used very large strength, i.e. time-consuming, effort.
Therefore, need for the macromolecular extraction of active bio, develop a kind of conveniently micro-biological tissue milling tool, reduce the extent of damage of sample in grinding, the raising grinding efficiency is necessary.
The utility model content
The utility model provides a kind of adjustable micro-biological tissue mill for solving the problem in the present technology, and it can make that the sample waste is little, simple to operate, extraction efficiency is high and without cross pollution.
The utility model is achieved by the following technical solutions:
A kind of adjustable micro-biological tissue mill, it comprises grinding rod, manual handle or low speed electric drill.
Described grinding rod comprises grinding rod shank, grinding rod middle part, grinds head and shank flutes, described grinding rod shank is cylindrical, the grinding rod shank is provided with shank flutes, the size shape of described shank flutes and manual handle or the interlock of common electrical drill chuck shroud phase, described grinding rod middle part be cylindrical, and described grinding head matches for long taper or taper shape and with the disposable centrifuge tube of commercially available common model;
Described manual handle comprises rolling disc and cutting ferrule two parts, and described rolling disc periphery and top are respectively equipped with some marginal band sections and convex stripe section, be provided with in the described rolling disc 2-4 raised item and with the shank flutes phase interlock of grinding rod.
Preferably, described adjustable micro-biological tissue mill, described grinding rod is as the electric drill rotary head.
Preferably, described adjustable micro-biological tissue mill, the shank diameter of described grinding rod is 10mm, the middle and lower part diameter of grinding rod is 6 ~ 10mm, the long 110mm of grinding rod, grinding head minister 10 ~ 15mm.
Preferably, described adjustable micro-biological tissue mill, the internal diameter 10mm of described cutting ferrule.
Preferably, described adjustable micro-biological tissue mill, it is material that grinding rod adopts glass or high hardness resin.
The utility model is compared the beneficial effect that has with existing other milling tool:
1, the sample waste is little.The present invention can measure the specification of adjusting at any time grinding rod per sample, satisfies to greatest extent the experiment needs, avoids simultaneously the waste of material.
2, simple to operation.Cooperate with manual handle, can increase the hold of grinding rod and grind revolving force, the convenient operation person uses, and is applicable to the grinding of a small amount of sample, and the operation in the unpowered situation.
3, extraction efficiency is high.Be used with the low speed electric drill, but finish the grinding of high flux sample within a short period of time, can greatly improve grinding efficiency and quality.
4, without cross pollution.Sample can adopt disposable centrifuge tube and grinding rod independently.In whole process of lapping, sample is complete to be retained in the centrifuge tube, has not only saved sample but also can avoid the cross pollution of sample room.
Description of drawings
Fig. 1 is the structural representation of grinding rod in the utility model;
Fig. 2 is the structure top view of manual handle in the utility model;
Fig. 3 is the structure upward view of manual handle in the utility model;
Fig. 4 is grinding rod and common electric drill combination schematic diagram.
The explanation of symbol in the accompanying drawing:
1, grinding rod shank, 2, grinding rod middle part, 3, grind head, 4, shank flutes, 5, the Handheld Division, 6, convex stripe section, 7, marginal band section, 8, cutting ferrule, 9 raised items.
The specific embodiment
With reference to the accompanying drawings the utility model specific embodiment is elaborated.
The structural representation of grinding rod in the utility model such as Fig. 1; Fig. 2 is the structure top view of manual handle in the utility model; Fig. 3 is the structure upward view of manual handle in the utility model; Fig. 4 is grinding rod and common electric drill combination schematic diagram.
Referring to Fig. 1, Fig. 2, Fig. 3, Fig. 4.
A kind of adjustable micro-biological tissue mill, it comprises grinding rod, manual handle or low speed electric drill.
Described grinding rod comprises grinding rod shank 1, grinding rod middle part 2, grinds head 3 and shank flutes 4, described grinding rod shank is cylindrical, the grinding rod shank is provided with shank flutes 4, the size shape of described shank flutes 4 and manual handle or the interlock of common electrical drill chuck shroud phase, described grinding rod middle part 2 is cylindrical, described grinding head 3 is seen Fig. 1, Fig. 4 for long taper or conical and match with the disposable centrifuge tube of commercially available common model.
Described manual handle comprises rolling disc and cutting ferrule 8 two parts, described rolling disc periphery and top are respectively equipped with some marginal band sections 7 and convex stripe section 6, be provided with in the described rolling disc 2-4 raised item 9 and with the shank flutes 4 phase interlocks of grinding rod, see Fig. 1, Fig. 2, Fig. 3.
Described grinding rod is as the electric drill rotary head.
The shank diameter of described grinding rod is 10mm, and the middle and lower part diameter of grinding rod is 6 ~ 10mm, the long 110mm of grinding rod, grinding head minister 10 ~ 15mm.
The internal diameter 10mm of described cutting ferrule 8.
It is material that described grinding rod adopts glass or high hardness resin, but the direct voltage sterilization.
Grinding rod can be different size, corresponding relation such as the following table of the specifications parameter of grinding rod and commercially available common disposable centrifuge tube model:
| The grinding rod specification | I | II | III | Ⅳ |
| The shank diameter | 10mm | 10mm | 10mm | 10mm |
| The middle and lower part diameter | 6mm | 8mm | 8mm | 10mm |
| Total length | 110mm | 110mm | 110mm | 110mm |
| The grinding head shape | Long taper | Long taper | Conical | Conical |
| Grinding head length | 10mm | 15mm | 10mm | 10mm |
| The centrifuge tube model | 0.5ml | 1.5ml | 2.0ml | 5ml |
The using method of a kind of adjustable micro-biological tissue of the utility model mill is as follows:
According to biological tissue samples amount and quantity, select the grinding rod of disposable centrifuge tube and respective numbers.
With the centrifuge tube ice bath, it is for subsequent use to add micro-biological tissue, Extraction buffer and grinding aid (quartz sand).
The moving handle of player or low speed electric drill are joined in the assembling of mill as required.When the player moves, hold Handheld Division 5 grinding rod is installed, manually can grind biological tissue samples; Select when electronic, grinding rod and common electric drill are assembled use, see Fig. 4.
Under condition of ice bath, finish grinding.
Centrifuge tube and grind after sample can be directly used in the subsequent experimental operations such as centrifugal, extraction.
Grinding rod cleaning, sterilization, drying for standby.
The utility model is applicable to the micro-examples such as various plant tissues (such as root, blade, stem, fruit, flower etc.), animal tissue's (such as muscle, internal organs, skin etc.), cell, fungi, and (grinding of V＜1ml) is broken, mix and the processing that homogenizes, and is particularly particularly applicable when specimen material is rare.In use, it is the committed step that guarantees large biological molecule activity and acquisition amount that the selection of grinding rod, ice bath grind.
Claims (5)
1. adjustable micro-biological tissue mill, it is characterized in that: it comprises grinding rod, manual handle or low speed electric drill;
Described grinding rod comprises grinding rod shank (1), grinding rod middle part (2), grinds head (3) and shank flutes (4), described grinding rod shank (1) is cylindrical, described grinding rod shank is provided with shank flutes (4), the size shape of described shank flutes (4) and manual handle or the interlock of common electrical drill chuck shroud phase, described grinding rod middle part (2) be cylindrical, and described grinding head (3) matches for long taper or taper shape and with the disposable centrifuge tube of commercially available common model;
Described manual handle comprises rolling disc and cutting ferrule (8) two parts, described rolling disc periphery and top are respectively equipped with some marginal band sections (7) and convex stripe section (6), be provided with in the described rolling disc 2-4 raised item (9) and with shank flutes (4) the phase interlock of grinding rod.
2. adjustable micro-biological tissue as claimed in claim 1 mill, it is characterized in that: described grinding rod is as the electric drill rotary head.
3. adjustable micro-biological tissue as claimed in claim 1 mill, it is characterized in that: the shank diameter of described grinding rod is 10mm, the middle and lower part diameter of grinding rod is 6 ~ 10mm, the long 110mm of grinding rod, grinding head minister 10 ~ 15mm.
4. adjustable micro-biological tissue as claimed in claim 1 mill is characterized in that:
The internal diameter 10mm of described cutting ferrule (8).
5. adjustable micro-biological tissue as claimed in claim 1 mill, it is characterized in that: it is material that grinding rod adopts glass or high hardness resin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220272164 CN202638537U (en) | 2012-06-07 | 2012-06-07 | Adjustable micro biological tissue grinder |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220272164 CN202638537U (en) | 2012-06-07 | 2012-06-07 | Adjustable micro biological tissue grinder |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202638537U true CN202638537U (en) | 2013-01-02 |
Family
ID=47407716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201220272164 Expired - Fee Related CN202638537U (en) | 2012-06-07 | 2012-06-07 | Adjustable micro biological tissue grinder |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202638537U (en) |
-
2012
- 2012-06-07 CN CN 201220272164 patent/CN202638537U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130102 Termination date: 20130607 |