CN202537710U - Combined building block type artificial bone - Google Patents

Combined building block type artificial bone Download PDF

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Publication number
CN202537710U
CN202537710U CN 201220048227 CN201220048227U CN202537710U CN 202537710 U CN202537710 U CN 202537710U CN 201220048227 CN201220048227 CN 201220048227 CN 201220048227 U CN201220048227 U CN 201220048227U CN 202537710 U CN202537710 U CN 202537710U
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CN
China
Prior art keywords
artificial bone
fin
face
substrate
monomer
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Expired - Lifetime
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CN 201220048227
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Chinese (zh)
Inventor
干耀恺
戴尅戎
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Ninth Peoples Hospital Shanghai Jiaotong University School of Medicine
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Ninth Peoples Hospital Shanghai Jiaotong University School of Medicine
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Application filed by Ninth Peoples Hospital Shanghai Jiaotong University School of Medicine filed Critical Ninth Peoples Hospital Shanghai Jiaotong University School of Medicine
Priority to CN 201220048227 priority Critical patent/CN202537710U/en
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Publication of CN202537710U publication Critical patent/CN202537710U/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof

Abstract

The utility model discloses combined building block type artificial bone. The artificial bone consists of a plurality of rows of artificial bone units which are docked vertically. Each artificial bone unit consists of a plurality of single bases and a single connector which are docked bilaterally. The single bases and the single connectors made of porous degradable biological materials (such as porous degradable calcium phosphorus ceramics). A great quantity of screened rich bone marrow stem cells are quickly adsorbed on the surface or the internal structure of the porous materials, so that the artificial bone and the bone marrow stem cells can be combined to jointly act on repairing defect of large bone.

Description

A kind of combination cordwood artificial bone
Technical field
This utility model relates to medical instruments field, relates in particular to a kind of combination cordwood porous, degradable artificial bone biomaterial.
Background technology
For a long time always as the goldstandard of repairing bone defect, all orthopedists admit this point from the body bone.Complicated at some, knitting is in the operation of difficulty, even exist at present some can with the method that matches in excellence or beauty from the body bone photo, the orthopedist still likes using from body bone bone grafting and comes repairing bone defect, to guarantee therapeutic effect.
And ilium is the most general area (Figure 11) that supplies bone from the body bone, but bulk after the body bone is excavated, the damaged problem of bringing of the iatrogenic bone that causes is a lot; Comprise pain, hematoma, celiocele, in addition patient's later stage can't be to use belt, and take down the back ilium can't regenerate; This like " only know lumbering; and do not know afforestation " harm, if repair ilium in the lump after therefore in stage operation, getting bone, this will be an invention.
It is damaged that previously simple utilization artificial bone generally can't be repaired the bulk bone; And bone marrow stem cell is proved and can adheres to enrichment fast in that the bone defect is local; Play the effect that promotes osteanagenesis and knitting; Our design and applied for related patent U.S. Patent No. (a kind of stem cell filtering screening enrichment and set composite fast: 201010187214.6) can combine the combined effect of artificial bone and bone marrow stem cell thus; That is repaired, and the bulk bone is damaged will to become possibility, but present artificial bone does not possess the function of carrying bone marrow stem cell.
Simultaneously, for the damaged focus of the bone in whole body extremity, skull, the spinal column, maybe need use the form of bone grafting; Different sizes; Changeful, often need to prune, almost be impossible if design can be satisfied the artificial bone structure of various situation; Prune in the art temporarily, tend to destroy the configuration of artificial bone.
Summary of the invention
The purpose of this utility model is to overcome the defective of prior art and a kind of combination cordwood artificial bone is provided; This artificial bone is through the various required shapes of some monomers one-tenth capable of being combined; To satisfy the demand of bone defect, this artificial bone can also carry the bone marrow stem cell of a large amount of rapid screening enrichments in advance simultaneously.
The purpose of this utility model is achieved in that
A kind of combination cordwood porous, degradable artificial bone of this utility model; This artificial bone is pegged graft up and down by plurality of rows artificial bone unit and is formed; Said artificial bone unit is connected the arrangement of pegging graft about monomer by several substrate monomers and forms with one, said artificial bone unit is processed by the porous, degradable biomaterial.
Above-mentioned a kind of combination cordwood artificial bone, wherein, the cross central line place of said artificial bone unit end face is provided with the grafting fin, and its bottom surface is provided with the grafting draw-in groove that is complementary with said grafting fin.
Above-mentioned a kind of combination cordwood artificial bone; Wherein, Said substrate monomer is the cuboid structure; The cross central line place of its end face be provided with one extend to the end face right side edge from end face left side always the end face fin; And the right side edge of this end face fin extends to form the side fin downwards, and cross central line place, said substrate monomer bottom surface is provided with the bottom surface draw-in groove that is complementary with said end face fin and runs through whole bottom surface, and said substrate monomer left surface longitudinal centre line place is provided with one and is complementary with said side fin and runs through the side bayonet slot of whole left face.
Above-mentioned a kind of combination cordwood artificial bone; Wherein, Said connection monomer is the cuboid structure; Its end face centre is provided with and the identical last fin of said end face fin width, and longitudinal centre line place, the monomeric left and right side of said connection is provided with one respectively and is complementary with said side fin and runs through whole lateral left and right draw-in groove, and cross central line place, said connection monomer bottom surface is provided with the lower bayonet slot that is complementary with said end face fin and runs through whole bottom surface.
Above-mentioned a kind of combination cordwood artificial bone; Wherein, Said artificial bone unit is connected monomer by several substrate monomers and forms with the grafting cooperation that is connected a monomeric left side/right draw-in groove with side bayonet slot or the monomeric side fin of substrate through the monomeric side fin of substrate with one; Wherein the monomeric end face fin of substrate be connected the monomeric fin of going up and formed the unitary grafting fin of said artificial bone, the monomeric bottom surface of substrate draw-in groove be connected monomeric lower bayonet slot and formed the unitary grafting draw-in groove of said artificial bone.
Above-mentioned a kind of combination cordwood artificial bone, wherein, said porous, degradable biomaterial is the porous, degradable Ca-P ceramic.
This utility model artificial bone is through the various required shapes of some monomers one-tenth capable of being combined; To satisfy the demand of bone defect; This utility model artificial bone is through the surface or the inner bone marrow stem cell that can carry a large amount of rapid screening enrichments in advance of its porous material simultaneously; Thus, the combinable combined effect of artificial bone and bone marrow stem cell is damaged in repairing the bulk bone.It is damaged to get bone residual behind the bone like the bulk ilium.
Description of drawings
Fig. 1 is the monomeric master of the substrate right axonometric chart of bowing in this utility model;
Fig. 2 is that the monomeric master of substrate faces upward left axonometric chart in this utility model;
Fig. 3 connects the monomeric master right axonometric chart of bowing in this utility model;
Fig. 4 connects monomeric master to face upward left axonometric chart in this utility model;
Fig. 5 is the unitary anabolic process sketch map of artificial bone in this utility model;
Fig. 6 is the master of artificial bone unit combination state among Fig. 5 right axonometric chart of bowing;
Fig. 7 is that the master of artificial bone unit combination state among Fig. 5 faces upward left axonometric chart;
Fig. 8 is the structural representation of the another kind of assembled state in artificial bone unit;
Fig. 9 is the anabolic process sketch map of this utility model artificial bone;
Figure 10 is the structural representation of this utility model artificial bone assembled state;
Figure 11 is the damaged sketch map of ilium bone.
The specific embodiment
To combine accompanying drawing that this utility model is described further below.
See also Fig. 1 and Fig. 2, the monomeric structure of substrate in this utility model has been shown among the figure.This substrate monomer 1 is the cuboid structure; The cross central line place of its end face be provided with one extend to the end face right side edge from end face left side always end face fin 11; And the right side edge of this end face fin 11 extends to form side fin 12 downwards; Cross central line place, substrate monomer 1 bottom surface is provided with the bottom surface draw-in groove 13 that is complementary with end face fin 11 and runs through whole bottom surface, and substrate monomer 1 left surface longitudinal centre line place is provided with one and is complementary with side fin 12 and runs through the side bayonet slot 14 of whole left face.
See also Fig. 3 and Fig. 4, the monomeric structure of connection in this utility model has been shown among the figure.This connects monomer 2 is the cuboid structure; Its end face centre is provided with and the identical last fin 21 of substrate monomer 1 end face fin 11 width; The longitudinal centre line place, left and right side that connects monomer 2 is provided with one respectively and is complementary with substrate monomer 1 side fin 12 and runs through whole lateral left draw-in groove 23 and right draw-in groove 22, connects cross central line place, monomer 2 bottom surface and is provided with the lower bayonet slot 24 that is complementary with end face fin 11 and runs through whole bottom surface.
Above-mentioned base unit 1 be connected monomer 2 and process by porous, degradable Ca-P ceramic material.
Artificial bone unit 3 is connected side bayonet slot 14 or the substrate monomer 1 of the side fin 12 of monomer 2 through substrate monomer 1 and another substrate monomer 1 by several substrate monomers 1 with one side fin 12 cooperates with the grafting of the left draw-in groove that is connected monomer 2 23/ right draw-in groove 22 and combines.
Fig. 5 shows the anabolic process of artificial bone unit 3; This artificial bone unit 3 by 4 substrate monomers 1 be connected monomer 2 and form; One of them substrate monomer 1 is plugged in the side bayonet slot 14 of another substrate monomer 1 that is adjacent through its side fin 12; Peg graft successively in a row thus, wherein the side fin 12 of rightmost side substrate monomer 1 is pegged graft with the left draw-in groove that is connected monomer 2 and is cooperated, and is combined to form artificial bone unit 3 at last.
See also Fig. 6 and Fig. 7; The stereochemical structure of artificial bone unit 3 has been shown among the figure; Wherein the end face fin 11 of substrate monomer 1 and the last fin 21 that is connected monomer 2 are connected to form the grafting fin 31 of artificial bone unit 3, and the bottom surface draw-in groove 13 of substrate monomer 1 and the lower bayonet slot that is connected monomer 2 24 are connected to form the grafting draw-in groove 32 of artificial bone unit 3.
The position that connection monomer 2 is positioned at artificial bone unit 3 can change arbitrarily, but principle is exactly only to contain one in line-up worker's osteon 3 to connect monomer 2.Fig. 8 shows the assembled state of another kind of artificial bone unit 3, this artificial bone unit 3 by 4 substrate monomers 1 be connected monomer 2 and form, wherein connect monomer 2 about respectively be connected with 2 substrate monomers 1.
This utility model artificial bone is combined by the grafting cooperation of plurality of rows artificial bone unit 3 through its grafting fin 31 and grafting draw-in groove 32.
Fig. 9 shows the anabolic process of this utility model artificial bone; This artificial bone 4 is made up of 3 row's artificial bone unit 3; Wherein line-up worker's osteon 3 is plugged in the grafting draw-in groove 32 of another row's artificial bone unit 3 that is adjacent through its grafting fin 31; Pegging graft successively thus forms, and Figure 10 shows the assembled state of artificial bone 4.
Operation principle: earlier with a plurality of substrate monomers of some with is connected monomer and filters also compound bone marrow stem cell of the middle rapid screening enrichment of recombiner (it is in 201010187214.6 the patent that this device is recorded in application number) in the stem cell circulation; At operation quick preparation same period active biomaterial; Then according to the size of bone defect; Some substrate monomers be connected the required shape of monomer one-tenth capable of being combined; (the bulk ilium shown in figure 11 bone of getting the bone postoperative is damaged to satisfy the demand that bulk bone defect repairs; Wherein A is the bone defect); Because the monomer of this utility model artificial bone is processed by porous, degradable biomaterial (like the porous, degradable Ca-P ceramic), therefore can the bone marrow stem cell rapid screening be enriched in the surface of artificial bone porous material or inner, and then it is damaged that the artificial bone of compound a large amount of bone marrow stem cells is used to repair the bulk bone through quick filtration screening enrichment mode.
Above embodiment only supplies to explain the usefulness of this utility model; But not to the restriction of this utility model; The technical staff in relevant technologies field under the situation of spirit that does not break away from this utility model and scope, can also make various conversion or modification; Therefore all technical schemes that are equal to also should belong to the category of this utility model, should be limited each claim.

Claims (6)

1. combination cordwood artificial bone; It is characterized in that; Said artificial bone is pegged graft up and down by plurality of rows artificial bone unit and is formed, and said artificial bone unit is connected the arrangement of pegging graft about monomer by several substrate monomers and forms with one, and said artificial bone unit is processed by the porous, degradable biomaterial.
2. a kind of combination cordwood artificial bone as claimed in claim 1 is characterized in that, the cross central line place of said artificial bone unit end face is provided with the grafting fin, and its bottom surface is provided with the grafting draw-in groove that is complementary with said grafting fin.
3. a kind of combination cordwood artificial bone as claimed in claim 1; It is characterized in that; Said substrate monomer is the cuboid structure; The cross central line place of its end face be provided with one extend to the end face right side edge from end face left side always the end face fin; And the right side edge of this end face fin extends to form the side fin downwards, and cross central line place, said substrate monomer bottom surface is provided with the bottom surface draw-in groove that is complementary with said end face fin and runs through whole bottom surface, and said substrate monomer left surface longitudinal centre line place is provided with one and is complementary with said side fin and runs through the side bayonet slot of whole left face.
4. a kind of combination cordwood artificial bone as claimed in claim 1; It is characterized in that; Said connection monomer is the cuboid structure; Its end face centre is provided with and the identical last fin of said end face fin width, and longitudinal centre line place, the monomeric left and right side of said connection is provided with one respectively and is complementary with said side fin and runs through whole lateral left and right draw-in groove, and cross central line place, said connection monomer bottom surface is provided with the lower bayonet slot that is complementary with said end face fin and runs through whole bottom surface.
5. like each described a kind of combination cordwood artificial bone of claim 1 to 4; It is characterized in that; Said artificial bone unit is connected monomer by several substrate monomers and forms with the grafting cooperation that is connected a monomeric left side/right draw-in groove with side bayonet slot or the monomeric side fin of substrate through the monomeric side fin of substrate with one; Wherein the monomeric end face fin of substrate be connected the monomeric fin of going up and formed the unitary grafting fin of said artificial bone, the monomeric bottom surface of substrate draw-in groove be connected monomeric lower bayonet slot and formed the unitary grafting draw-in groove of said artificial bone.
6. a kind of combination cordwood artificial bone as claimed in claim 1 is characterized in that said porous, degradable biomaterial is the porous, degradable Ca-P ceramic.
CN 201220048227 2012-02-15 2012-02-15 Combined building block type artificial bone Expired - Lifetime CN202537710U (en)

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CN 201220048227 CN202537710U (en) 2012-02-15 2012-02-15 Combined building block type artificial bone

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Application Number Priority Date Filing Date Title
CN 201220048227 CN202537710U (en) 2012-02-15 2012-02-15 Combined building block type artificial bone

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111904667A (en) * 2020-09-08 2020-11-10 四川大学 Self-locking segmentation design method for maxillary defect prosthesis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111904667A (en) * 2020-09-08 2020-11-10 四川大学 Self-locking segmentation design method for maxillary defect prosthesis

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Granted publication date: 20121121