CN202527166U - Closed mobile phase accommodating device for liquid chromatography - Google Patents
Closed mobile phase accommodating device for liquid chromatography Download PDFInfo
- Publication number
- CN202527166U CN202527166U CN2012201517948U CN201220151794U CN202527166U CN 202527166 U CN202527166 U CN 202527166U CN 2012201517948 U CN2012201517948 U CN 2012201517948U CN 201220151794 U CN201220151794 U CN 201220151794U CN 202527166 U CN202527166 U CN 202527166U
- Authority
- CN
- China
- Prior art keywords
- flowing phase
- bottle
- phase
- valve
- exhaust outlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Landscapes
- Degasification And Air Bubble Elimination (AREA)
Abstract
The utility model discloses a closed mobile phase accommodating device for liquid chromatography. The device comprises a sealed container for accommodating a mobile phase for liquid chromatography, the sealed container is connected with a liquid inlet pipe connected with a liquid phase system, and one end of the liquid inlet pipe extends into the mobile phase in the sealed container; two ventilation structures are also arranged on the sealed container, and each of the two ventilation structures is provided with a ventilation cavity communicated with the upper space of the liquid level of the mobile phase in the sealed container; and one ventilation structure is provided with a valve, the other ventilation structure is communicated with a flexible bag, and the flexible bag is provided with a vent with a valve. By adopting the device, the problems that the pH value of the mobile phase is changed because the mobile phase absorbs carbon dioxide in air and the proportion of components in the mobile phase is changed because organic components in the mobile phase are volatilized can be solved, the liquid phase measuring result is accurate and reliable, and damage to environment and human body due to organic solvents and irritating components can be reduced.
Description
Technical field
The utility model relates to a kind of closed phase chromatography-use flowing phase apparatus for placing.
Background technology
The high performance liquid chromatography that holds at present commonly used all is the open type that communicates with air with the solvent bottle of flowing phase; As shown in Figure 1; Open type flowing phase apparatus for placing is for common flowing phase commonly used; Be not much affected, but for be prone to absorb Carbon Dioxide in Air and influence flowing phase (particularly pH value shows the flowing phase of alkalescence), the volatile flowing phase (the organic facies proportion is bigger) and the flowing phase that contains the excitant component of its pH value, significant limitation is arranged.
Open type flowing phase apparatus for placing can't solve flowing phase at all and absorb the influence of Carbon Dioxide in Air to its pH value; Particularly pH value shows the flowing phase of alkalescence; And this type flowing phase also can run in the liquid phase assay method, and this necessitates with regard to the appearance that makes closed phase chromatography-use flowing phase apparatus for placing.
Summary of the invention
The purpose of the utility model is for overcoming the deficiency of above-mentioned prior art, a kind of closed phase chromatography-use flowing phase apparatus for placing being provided.
For realizing above-mentioned purpose, the utility model adopts following technical proposals:
A kind of closed phase chromatography-use flowing phase apparatus for placing, it comprises the airtight container that holds phase chromatography-use flowing phase, airtight container links to each other with the feed tube that is connected liquid phase systems, and an end of this feed tube extend in the flowing phase in the airtight container; Also be provided with two ventilation devices on the sealing container, all have the venting cavity of the upper space of flowing phase liquid level in the communication seals container on these two ventilation devices; One of them ventilation device is provided with valve, and another ventilation device is communicated with soft bag, also is provided with a blow vent that has valve on the soft bag.
The end that the upper space of flowing phase liquid level is communicated with in venting cavity and the airtight container is an exhaust outlet, the exhaust outlet of one of them ventilation device on the short transverse near the liquid level of flowing phase; The exhaust outlet of another ventilation device on the short transverse away from the liquid level of flowing phase.
The junction of said soft bag and ventilation device is provided with valve.
The end that said feed tube extend in the said airtight container is provided with solvent filter.
Said airtight container is made up of solvent bottle and bottle stopper, perhaps is made up of the solvent Bottle and bottle cap.
One of them ventilation device is: it is located at the side of solvent bottle upper end, and is integrally formed structure with solvent bottle bottle wall; Bottle stopper or bottle cap are provided with two through holes; Another ventilation device is: pass the breather pipe of one of them through hole, the end that this breather pipe is positioned at solvent bottle is an exhaust outlet, this exhaust outlet on the short transverse near the liquid level of flowing phase; Said feed tube passes another through hole.
Bottle stopper or bottle cap are provided with three through holes, and one of them ventilation device is: pass the breather pipe of one of them through hole, an end that is positioned at solvent bottle of this breather pipe is an exhaust outlet, this exhaust outlet on the short transverse near the liquid level of flowing phase; Another ventilation device is: pass the breather pipe of another through hole, an end that is positioned at solvent bottle of this breather pipe is an exhaust outlet, this exhaust outlet on the short transverse away from the liquid level of flowing phase; Said feed tube passes the 3rd through hole.
Between above-mentioned solvent bottle and bottle stopper or the bottle cap, and all be tightly connected between the through hole on feed tube and breather pipe and bottle stopper or the bottle cap, guarantee to form on the whole an airtight container.When breather pipe when through hole passes, the glass tube that breather pipe can adopt both ends open to have venting cavity is processed.When breather pipe is positioned at the side of solvent agent upper end; Breather pipe is that the bottle wall of solvent bottle outwards stretches the structure that forms tubulose; Itself and solvent bottle itself are structure as a whole, and also can regard the part of solvent bottle as, at this time; Because the exhaust outlet of this breather pipe flushes with the solvent bottle inwall and is positioned at the side on the solvent bottle, so also be exhaust outlet on the short transverse near the liquid level of flowing phase.
Soft bag is processed (such as polypropylene, Kynoar etc.) by the macromolecular material of organic solvent-resistant, acid and alkali-resistance, can inflated with nitrogen between its citadel etc. inert gas.
With those skilled in the art's understanding, airtight container should be provided with one and can flowing phase be contained into the opening in (or pouring into) airtight container, and can open the lid with seal closure, adds bottle stopper or bottle cap such as solvent bottle.
Owing to the difference that is sealed with of inert gas and air, upwards emptying gas method is used for the density inert gas bigger than atmospheric density, and emptying gas method is used for the density inert gas littler than atmospheric density downwards.The inert gas here refers to and comprises rare gas or nitrogen.When inert gas is nitrogen; Because density of nitrogen is littler than atmospheric density; So adopt downward emptying gas method, be air inlet one end with exhaust outlet ventilation device near the liquid level of flowing phase on the short transverse, with exhaust outlet on the short transverse away from the ventilation device of the liquid level of the flowing phase end of giving vent to anger.
Its basic method for using is: flowing phase is contained in the airtight container of this device; Behind the ultrasonic degas; (with bottle cap or bottle stopper fixing seal on solvent bottle) connected valve between valve, soft bag and the airtight container and the valve on the breather pipe on the blow vent, charges into inert gas (when inert gas is nitrogen; Selecting exhaust outlet ventilation device near the liquid level of flowing phase on the short transverse is air inlet one end); After waiting to replace the air in the device seal area, stop to charge into inert gas, close the valve on the valve and breather pipe on the blow vent then.Then, carry out the operation of liquid phase, this moment, flowing phase got in the liquid chromatographic system through feed tube; Flowing phase liquid level in the airtight container descends; It is big that the space of liquid level top becomes, and the inert gas that stores in the soft bag gets in the space in the sealing container and since soft bag neither the container of fixed volume; There is not elasticity, so can protect the airtight container internal gas pressure constant yet.
Compared with prior art; The beneficial effect of the utility model is; Adopt this device, can solve flowing phase and absorb carbon dioxide in air and the flowing phase pH value is changed, can solve the volatilization of organic component in the flowing phase again and the ratio of each component of flowing phase is changed; Huaihe River is really reliable more to make liquid phase measure the result, can reduce the infringement to environment and human body of organic solvent and excitant component simultaneously.
Description of drawings
Fig. 1 is the structural representation in the background technology;
Fig. 2 is the structural representation of embodiment 1;
Fig. 3 is the structural representation of embodiment 2;
Fig. 4 is the structural representation of embodiment 3;
Fig. 5 is the structural representation of embodiment 4.
1. solvent bottles wherein, 2. bottle stopper (or bottle cap), 3. breather pipe, 4. exhaust outlet, 5. feed tube, 6. soft bag, 7. blow vent, 8. valve A, 9. valve B, 10. valve C, 11. solvent filters, 12. flowing phases.
Solid arrow is represented the direction that flowing phase flows, and considers the direction that the line arrow is represented inert gas flows.
The specific embodiment
Below in conjunction with accompanying drawing and embodiment the utility model is further specified.
As shown in Figure 2, a kind of closed phase chromatography-use flowing phase apparatus for placing, it comprises the airtight container that holds phase chromatography-use flowing phase, airtight container is made up of solvent bottle 1 and bottle stopper 2; Also be provided with two ventilation devices on the sealing container, all have the venting cavity of the upper space of flowing phase 12 liquid levels in the communication seals container on these two ventilation devices, venting cavity is an exhaust outlet 4 with the end that the upper space of flowing phase 12 liquid levels in the airtight container is communicated with.
The feed tube 5 that connects liquid phase systems passes one of them through hole, and an end of this feed tube 5 extend in the flowing phase 12 in the airtight container, and the end that said feed tube 5 extend in the said airtight container is provided with solvent filter 11 (also being filtering head or filter).
One of them ventilation device is: it is located at the side of solvent bottle 1 upper end, and is integrally formed structure with 1 bottle of wall of solvent bottle.The exhaust outlet 4 of this ventilation device on the short transverse away from the liquid level of flowing phase 12; This ventilation device one end is connected with solvent bottle 1 inner space, and the other end is communicated with soft bag 6, also is provided with a blow vent 7 that has valve (valve A8) on the soft bag 6.Said soft bag 6 is provided with valve (valve B9) with the junction of ventilation device.
Another ventilation device is: pass the breather pipe 3 of another through hole, the end that this breather pipe 3 is positioned at solvent bottle 1 is an exhaust outlet 4, and near the liquid level of flowing phase 12, the other end of breather pipe 3 is provided with valve (valve C10) to this exhaust outlet 4 on the short transverse.
Between above-mentioned solvent bottle 1 and the bottle stopper 2, and all be tightly connected between the through hole on feed tube 5 and breather pipe 3 and the bottle stopper 2, guarantee to form on the whole an airtight container.
Method for using:
As shown in Figure 3, a kind of closed phase chromatography-use flowing phase apparatus for placing, it comprises the airtight container that holds phase chromatography-use flowing phase, airtight container is made up of solvent bottle 1 and bottle cap 2; Also be provided with two ventilation devices on the sealing container, all have the venting cavity of the upper space of flowing phase 12 liquid levels in the communication seals container on these two ventilation devices, venting cavity is an exhaust outlet 4 with the end that the upper space of flowing phase 12 liquid levels in the airtight container is communicated with.
Bottle cap 2 is provided with two through holes.
The feed tube 5 that connects liquid phase systems passes one of them through hole, and an end of this feed tube 5 extend in the flowing phase 12 in the airtight container, and the end that said feed tube 5 extend in the said airtight container is provided with solvent filter 11.
One of them ventilation device is: it is located at the side of solvent bottle 1 upper end, and is integrally formed structure with 1 bottle of wall of solvent bottle.The exhaust outlet 4 of this ventilation device on the short transverse away from the liquid level of flowing phase 12; This ventilation device one end is connected with solvent bottle 1 inner space, and the other end is provided with valve (valve C10).
Another ventilation device is: the breather pipe 3 that passes another through hole; The end that this breather pipe 3 is positioned at solvent bottle 1 is an exhaust outlet 4; This exhaust outlet 4 on the short transverse near the liquid level of flowing phase 12; The other end of breather pipe 3 is communicated with soft bag 6, also is provided with a blow vent 7 that has valve (valve A8) on the soft bag 6.Said soft bag 6 is provided with valve (valve B9) with the junction of ventilation device.
Between above-mentioned solvent bottle 1 and the bottle cap 2, and all be tightly connected between the through hole on feed tube 5 and breather pipe 3 and the bottle cap 2, guarantee to form on the whole an airtight container.
Method for using:
As shown in Figure 4, a kind of closed phase chromatography-use flowing phase apparatus for placing, it comprises the airtight container that holds phase chromatography-use flowing phase, airtight container is made up of solvent bottle and bottle stopper 2; Also be provided with two ventilation devices on the sealing container, all have the venting cavity of the upper space of flowing phase 12 liquid levels in the communication seals container on these two ventilation devices, venting cavity is an exhaust outlet 4 with the end that the upper space of flowing phase 12 liquid levels in the airtight container is communicated with.
The feed tube 5 that connects liquid phase systems passes one of them through hole, and an end of this feed tube 5 extend in the flowing phase 12 in the airtight container, and the end that said feed tube 5 extend in the said airtight container is provided with solvent filter 11.
One of them ventilation device is: pass the breather pipe 3 of another through hole, an end that is positioned at solvent bottle of this breather pipe 3 is an exhaust outlet 4, this exhaust outlet 4 on the short transverse near the liquid level of flowing phase 12; This ventilation device one end is connected with the solvent bottle inner space, and the other end is provided with valve (valve C10).
Another ventilation device is: the breather pipe 3 that passes the 3rd through hole; The end that this breather pipe 3 is positioned at solvent bottle is an exhaust outlet 4; This exhaust outlet 4 on the short transverse away from the liquid level of flowing phase 12; The other end of breather pipe 3 is communicated with soft bag 6, also is provided with a blow vent 7 that has valve (valve A8) on the soft bag 6.Said soft bag 6 is provided with valve (valve B9) with the junction of ventilation device.
Between above-mentioned solvent bottle and the bottle stopper 2, and all be tightly connected between the through hole on feed tube 5 and breather pipe 3 and the bottle stopper 2, guarantee to form on the whole an airtight container.
Method for using:
Flowing phase 12 is contained in the solvent bottle of this device, behind the ultrasonic degas, with bottle stopper 2 fixing seals on solvent bottle; Valve A8, valve B9 and valve C10 are connected; Charge into nitrogen (valve A8 air inlet, valve C10 gives vent to anger), after waiting to replace the air in the device seal area; Stop to fill nitrogen, then valve-off A8 and valve C10.
As shown in Figure 5, a kind of closed phase chromatography-use flowing phase apparatus for placing, it comprises the airtight container that holds phase chromatography-use flowing phase, airtight container is made up of solvent bottle and bottle stopper 2; Also be provided with two ventilation devices on the sealing container, all have the venting cavity of the upper space of flowing phase 12 liquid levels in the communication seals container on these two ventilation devices, venting cavity is an exhaust outlet 4 with the end that the upper space of flowing phase 12 liquid levels in the airtight container is communicated with.
The feed tube 5 that connects liquid phase systems passes one of them through hole, and an end of this feed tube 5 extend in the flowing phase 12 in the airtight container, and the end that said feed tube 5 extend in the said airtight container is provided with solvent filter 11.
One of them ventilation device is: pass the breather pipe 3 of another through hole, an end that is positioned at solvent bottle of this breather pipe 3 is an exhaust outlet 4, this exhaust outlet 4 on the short transverse away from the liquid level of flowing phase 12; This ventilation device one end is connected with the solvent bottle inner space, and the other end is provided with valve (valve C10).
Another ventilation device is: the breather pipe 3 that passes the 3rd through hole; The end that this breather pipe 3 is positioned at solvent bottle is an exhaust outlet 4; This exhaust outlet 4 on the short transverse near the liquid level of flowing phase 12; The other end of breather pipe 3 is communicated with soft bag 6, also is provided with a blow vent 7 that has valve (valve A8) on the soft bag 6.Said soft bag 6 is provided with valve (valve B9) with the junction of ventilation device.
Between above-mentioned solvent bottle and the bottle stopper 2, and all be tightly connected between the through hole on feed tube 5 and breather pipe 3 and the bottle stopper 2, guarantee to form on the whole an airtight container.
Method for using:
Flowing phase 12 is contained in the solvent bottle of this device, behind the ultrasonic degas, with bottle stopper 2 fixing seals on solvent bottle; Valve A8, valve B9 and valve C10 are connected; Charge into nitrogen (valve C10 air inlet, valve A8 gives vent to anger), after waiting to replace the air in the device seal area; Stop to fill nitrogen, then valve-off A8 and valve C10.
Claims (7)
1. closed phase chromatography-use flowing phase apparatus for placing; It is characterized in that; It comprises the airtight container that holds phase chromatography-use flowing phase, and airtight container links to each other with the feed tube that is connected liquid phase systems, and an end of this feed tube extend in the flowing phase in the airtight container; Also be provided with two ventilation devices on the sealing container, all have the venting cavity of the upper space of flowing phase liquid level in the communication seals container on these two ventilation devices; One of them ventilation device is provided with valve, and another ventilation device is communicated with soft bag, also is provided with a blow vent that has valve on the soft bag.
2. closed phase chromatography-use flowing phase apparatus for placing according to claim 1; It is characterized in that; The end that the upper space of flowing phase liquid level is communicated with in venting cavity and the airtight container is an exhaust outlet, the exhaust outlet of one of them ventilation device on the short transverse near the liquid level of flowing phase; The exhaust outlet of another ventilation device on the short transverse away from the liquid level of flowing phase.
3. closed phase chromatography-use flowing phase apparatus for placing according to claim 1 is characterized in that the junction of said soft bag and ventilation device is provided with valve.
4. closed phase chromatography-use flowing phase apparatus for placing according to claim 1 is characterized in that, the end that said feed tube extend in the said airtight container is provided with solvent filter.
5. according to each described closed phase chromatography-use flowing phase apparatus for placing of claim 1-4, it is characterized in that said airtight container is made up of solvent bottle and bottle stopper, perhaps form by the solvent Bottle and bottle cap.
6. closed phase chromatography-use flowing phase apparatus for placing according to claim 5 is characterized in that one of them ventilation device is: it is located at the side of solvent bottle upper end, and is integrally formed structure with solvent bottle bottle wall; Bottle stopper or bottle cap are provided with two through holes; Another ventilation device is: pass the breather pipe of one of them through hole, the end that this breather pipe is positioned at solvent bottle is an exhaust outlet, this exhaust outlet on the short transverse near the liquid level of flowing phase; Said feed tube passes another through hole.
7. closed phase chromatography-use flowing phase apparatus for placing according to claim 5; It is characterized in that; Bottle stopper or bottle cap are provided with three through holes; One of them ventilation device is: pass the breather pipe of one of them through hole, an end that is positioned at solvent bottle of this breather pipe is an exhaust outlet, this exhaust outlet on the short transverse near the liquid level of flowing phase; Another ventilation device is: pass the breather pipe of another through hole, an end that is positioned at solvent bottle of this breather pipe is an exhaust outlet, this exhaust outlet on the short transverse away from the liquid level of flowing phase; Said feed tube passes the 3rd through hole.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012201517948U CN202527166U (en) | 2012-04-12 | 2012-04-12 | Closed mobile phase accommodating device for liquid chromatography |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012201517948U CN202527166U (en) | 2012-04-12 | 2012-04-12 | Closed mobile phase accommodating device for liquid chromatography |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202527166U true CN202527166U (en) | 2012-11-14 |
Family
ID=47128374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012201517948U Expired - Fee Related CN202527166U (en) | 2012-04-12 | 2012-04-12 | Closed mobile phase accommodating device for liquid chromatography |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202527166U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102641711A (en) * | 2012-04-12 | 2012-08-22 | 山东创新药物研发有限公司 | Flowing phase containing device used for sealed liquid phase color spectrum |
| CN106895131A (en) * | 2015-12-21 | 2017-06-27 | 博世电动工具（中国）有限公司 | Sealing ventilation device and the equipment including it |
-
2012
- 2012-04-12 CN CN2012201517948U patent/CN202527166U/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102641711A (en) * | 2012-04-12 | 2012-08-22 | 山东创新药物研发有限公司 | Flowing phase containing device used for sealed liquid phase color spectrum |
| CN102641711B (en) * | 2012-04-12 | 2015-05-13 | 山东创新药物研发有限公司 | Flowing phase containing device used for sealed liquid phase color spectrum |
| CN106895131A (en) * | 2015-12-21 | 2017-06-27 | 博世电动工具（中国）有限公司 | Sealing ventilation device and the equipment including it |
| CN106895131B (en) * | 2015-12-21 | 2024-01-23 | 博世电动工具（中国）有限公司 | Sealing ventilation device and equipment comprising same |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN206107932U (en) | Sealed container of depositing of chemical product | |
| WO2012061054A3 (en) | Funnel-shaped container with capped ends | |
| RU2013131782A (en) | CONTAINERS AND METHODS OF ISOLATING LIQUIDS BEFORE DOSING | |
| CN202527166U (en) | Closed mobile phase accommodating device for liquid chromatography | |
| RU2014147698A (en) | BULK STORAGE CONTAINER AND LOADING AND UNLOADING UNIT | |
| CN201145692Y (en) | Portable static state box | |
| CN102641711B (en) | Flowing phase containing device used for sealed liquid phase color spectrum | |
| CN203034068U (en) | Inflation sealing device of molten aluminum degassing device | |
| CN105857877B (en) | A kind of red wine vacuum bottle stopper | |
| CN105938066B (en) | Apparatus for combining liquids and its mixed method | |
| CN211845744U (en) | Container device convenient to take | |
| WO2006072972A3 (en) | Dosing device for fluid substances | |
| CN206730668U (en) | Core Suction filtration device with valve outflow solution | |
| CN203946394U (en) | A kind of bottle cap for mobile phase bottle in liquid chromatography | |
| CN204602165U (en) | A kind of chemical reaction Simple negative-pressure pressurizer | |
| CN206057024U (en) | Closed type oils and fatss sampler | |
| CN207774752U (en) | A kind of tamponade device | |
| CN204768775U (en) | Measurement formula atmospheric pressure sampler | |
| CN2789164Y (en) | Liquid sealing container | |
| CN207292922U (en) | Novel liquid-phase chromatogram flow phase bottle cap | |
| CN105966749A (en) | Bottle cover capable of realizing mixing two and more than two components | |
| CN214471615U (en) | Air tightness detection device of engine cylinder head cover | |
| CN208751908U (en) | A kind of sampling bottle automatic sealing device | |
| CN203300712U (en) | Storage battery without press-fit sealing ring | |
| CN202098693U (en) | Air suction valve and vacuum compression bag adopting same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20121114 Termination date: 20140412 |