CN202526183U - Human tissue oxygen content monitor - Google Patents
Human tissue oxygen content monitor Download PDFInfo
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- CN202526183U CN202526183U CN201220137655XU CN201220137655U CN202526183U CN 202526183 U CN202526183 U CN 202526183U CN 201220137655X U CN201220137655X U CN 201220137655XU CN 201220137655 U CN201220137655 U CN 201220137655U CN 202526183 U CN202526183 U CN 202526183U
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Abstract
The utility model belongs to the technical field of biomedical engineering and particularly relates to an instrument for measuring human tissue oxygen content by a near infrared spectroscopy. The instrument comprises a reflection type sensor, a microprogrammed control unit (MCU) digital signal processing module, an emitting module, a receiving module, a corresponding interface circuit and a power management circuit, the reflection type sensor can be used to detect an optical signal, the reflection type sensor has functions of controlling a light source and transforming and amplifying the signal, a high brightness light emitting diode with luminescent wave length of 760nm to 850nm is used for the light source, a near infrared reflectance spectroscopy (NIRS) technology based on spatial discrimination is introduced to obtain oxygen saturation in real time, and two photoelectric detectors which have different distances from the light source are utilized as shown in picture. The instrument has the advantages that by means of near infrared spectrum, a real-time, continuous and nondestructive testing for the human tissue oxygen content is achieved, the real-time wireless transmission for the testing result is achieved, the size of the instrument is small, the control is simple, the performance is stable, and the instrument can be used for real-time monitoring for the athlete tissue oxygenation condition during athletic training.
Description
Technical field
This utility model belongs to the biomedical engineering technology field, particularly a kind of instrument that utilizes near-infrared spectrum technique to measure the tissue oxygen content.
Background technology
Hemoglobin is the main carrier of oxygen in the tissue, and it is by HbO2 Oxyhemoglobin (HbO
2) and reduced hemoglobin (Hb) composition, the oxygen in the tissue is to exist with the HbO2 Oxyhemoglobin form in the blood capillary in organizing basically.Blood oxygen saturation is meant HbO
2In hemoglobin (is HbO
2With Hb concentration sum) in the percentage ratio of content, along with the variation of human body aerobic metabolism situation, blood oxygen saturation can change.
Many clinically blood oxygen parameters that detect blood with two kinds of methods.The one, the wound blood gas analysis is arranged, promptly, obtain its blood oxygen parameter with biochemical method from trunk (tremulous pulse or the vein) blood drawing of human body.The 2nd, detect the finger tip detecting sphygmus and blood oxygen saturation, this is noninvasive optical detecting method, its sensor clip is at finger tip, detects principle based on the beating of finger tip tremulous pulse, and promptly extracts through interchange (beating) component of the emergent light of finger tip decay and resolves.Therefore blood oxygen saturation is actually the oxygen saturation of arterial blood, as long as the oxygen supply of human body finger tip tremulous pulse is normal, it is generally very near 100%.
Near infrared spectrum (NIRS) has become the important branch of Biomedical Photonics.Near infrared light has good penetrance to tissue, and research is illustrated in 700~900nm wave band HbO
2With Hb be absorber main in the tissue.Therefore near infrared light (several mW of light intensity get final product) is incided the tissue surface, detect of the decay of the emergent light of a certain position, just can obtain the tissue oxygenation situation for information about with respect to incident illumination.Above-mentioned detection be can't harm, real-time, successive, this is the outstanding advantage of NIRS just.
The specific algorithm that NIRS detects the tissue oxygenation parameter has following three kinds.The one, continuous wave (CW) method is used the incident illumination of constant intensity this moment, through detecting the light intensity attenuation of emergent light with respect to incident illumination, the blood oxygen parameter that obtains organizing.The 2nd, phase modulated (PMS) method, this moment, incident illumination was the sine wave of high frequency (100-200MHz), through detecting the strength retrogression and the Phase delay of the relative incident illumination of emergent light, the blood oxygen parameter that obtains organizing.The 3rd, time resolved spectroscopy (TRS) method, this moment, incident illumination was a ultrashort pulse (pulsewidth is the ps magnitude), through detecting the time response of emergent light, the blood oxygen parameter that obtains organizing.The CW method realizes that the most easily clinical practice is the most extensive, and PMS and TRS method realize difficulty relatively.
The oxygen saturation of tissue is the weighted average of the blood oxygen saturation of each autoblood in arteriole in the tested tissue, venule and the blood capillary; Because the flow velocity of venule blood is relatively slow, thus it in blood oxygen saturation in the highest flight.The blood oxygen saturation of tissue can reflect the dynamic equilibrium of supply of local organization oxygen and oxygen consumption, and is significant in the training monitoring.At present, in the motion field, the application of near infrared light mensuration tissue oxygen content is also fewer.
Summary of the invention
This utility model is a kind of instrument with near infrared light technology for detection tissue oxygen content; Its maximum characteristics be to have realized with near infrared spectrum to the tissue oxygen content carry out in real time, continuously, Non-Destructive Testing and to the real-time radio transmission of testing result; The instrument volume is little; Control is simple, stable performance.
This utility model specifically is made up of reflection sensor, MCU digital signal processing module, transmitter module, receiver module and corresponding interface circuits and electric power management circuit.Can adopt reflection sensor to realize detection to optical signal.Wherein reflection sensor has the control light source, signal transforms and the function of amplification.Adopt the steady and continuous ripple, the light source luminescent wavelength is the high bright light emitting diode of 760nm and 850nm; For obtaining blood oxygen saturation in real time, introduced NIRS technology based on spatial discrimination, use two photoelectric detectors different with light source distance; As shown in Figure 1.The wireless transmitter module of forming through nRF9E5 sends the information that records; The last wireless signal receiver of PC is sent on the PC through serial line interface after receiving information; After the digital filtering processing, on PC, demonstrate information such as blood oxygen saturation in real time, and preserve.
Description of drawings
Fig. 1 is instrument luminous tube and photoelectric detector sketch map
Fig. 2 is a nRF9E5 microcontroller flow chart
Fig. 3 is the real-time monitoring scheme block diagram of tissue oxygen
The specific embodiment
According to measuring point (like quadriceps femoris, triceps brachii), pick off is fixed on the corresponding position of measured.
It is luminous to tested tissue to drive near-infrared luminous pipe under the control of 8051 nuclears of light emission drive circuit in nRF9E5-1; Optical signal receiving circuit receives the light that transmits through tested tissue and produces the correspondent voltage signal; Programmable amplifying circuit carries out program control amplification to above-mentioned signal according to size and forms the transient data that moderate voltage confession ADC converts characterizing tissues oxygen to; NRF9E5-1 sends the tissue oxygen data to nRF9052; NRF905-2 meets MAX232 and sends data to PC with the RS232 level; PC handles, shows and preserve receiving the data of coming from the RS232 interface.
Claims (3)
1. a tissue oxygen content monitor is characterized in that adopting near-infrared spectrum technique, specifically is made up of reflection sensor, MCU digital signal processing module, transmitter module, receiver module and corresponding interface circuits and electric power management circuit.
2. a kind of tissue oxygen content monitor according to claim 1 is characterized in that adopting the steady and continuous ripple, and the light source luminescent wavelength is the high bright light emitting diode of 760nm and 850nm, uses two photoelectric detectors different with light source distance.
3. a kind of tissue oxygen content monitor according to claim 1; The wireless transmitter module of forming through nRF9E5 sends the information that records; The last wireless signal receiver of PC is sent on the PC through serial line interface after receiving information; After the digital filtering processing, on PC, demonstrate information such as blood oxygen saturation in real time, and preserve.
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CN201220137655XU CN202526183U (en) | 2012-04-05 | 2012-04-05 | Human tissue oxygen content monitor |
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CN201220137655XU CN202526183U (en) | 2012-04-05 | 2012-04-05 | Human tissue oxygen content monitor |
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Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103519826A (en) * | 2013-10-29 | 2014-01-22 | 北京新兴阳升科技有限公司 | Reflection-type blood oxygen saturation gauge and measuring method thereof |
CN103610467A (en) * | 2013-11-05 | 2014-03-05 | 李鲁亚 | Parallel near-infrared photoelectric sensing device and system and method for detecting organs and tissue of animals |
CN104134331A (en) * | 2014-07-16 | 2014-11-05 | 奉化市宇创产品设计有限公司 | WLAN-based infrared spectrometer |
CN106344041A (en) * | 2016-10-27 | 2017-01-25 | 北京雷致科技有限公司 | Oximeter and blood oxygen monitoring method |
CN109692008A (en) * | 2018-12-10 | 2019-04-30 | 中国人民解放军总医院 | Muscle oxygen based on NIRS technology closes detection device |
US10314499B2 (en) | 2014-07-18 | 2019-06-11 | Well Being Digital Limited | Device and method suitable for monitoring arterial blood in a body part |
CN110025320A (en) * | 2019-04-09 | 2019-07-19 | 中国人民解放军总医院 | A kind of muscle oxygen conjunction detection device bluetooth transmission means |
CN112043287A (en) * | 2020-09-30 | 2020-12-08 | 重庆大学 | Noninvasive monitoring method and monitoring device for cerebral blood oxygen |
-
2012
- 2012-04-05 CN CN201220137655XU patent/CN202526183U/en not_active Expired - Fee Related
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103519826A (en) * | 2013-10-29 | 2014-01-22 | 北京新兴阳升科技有限公司 | Reflection-type blood oxygen saturation gauge and measuring method thereof |
CN103519826B (en) * | 2013-10-29 | 2015-05-20 | 北京新兴阳升科技有限公司 | Reflection-type blood oxygen saturation gauge and measuring method thereof |
CN103610467A (en) * | 2013-11-05 | 2014-03-05 | 李鲁亚 | Parallel near-infrared photoelectric sensing device and system and method for detecting organs and tissue of animals |
CN104134331A (en) * | 2014-07-16 | 2014-11-05 | 奉化市宇创产品设计有限公司 | WLAN-based infrared spectrometer |
US10314499B2 (en) | 2014-07-18 | 2019-06-11 | Well Being Digital Limited | Device and method suitable for monitoring arterial blood in a body part |
US10806355B2 (en) | 2014-07-18 | 2020-10-20 | Well Being Digital Limited | Device and method suitable for monitoring arterial blood in a body part |
US11653846B2 (en) | 2014-07-18 | 2023-05-23 | Well Being Digital Limited | Device and method suitable for monitoring arterial blood in a body part |
CN106344041A (en) * | 2016-10-27 | 2017-01-25 | 北京雷致科技有限公司 | Oximeter and blood oxygen monitoring method |
CN109692008A (en) * | 2018-12-10 | 2019-04-30 | 中国人民解放军总医院 | Muscle oxygen based on NIRS technology closes detection device |
CN110025320A (en) * | 2019-04-09 | 2019-07-19 | 中国人民解放军总医院 | A kind of muscle oxygen conjunction detection device bluetooth transmission means |
CN112043287A (en) * | 2020-09-30 | 2020-12-08 | 重庆大学 | Noninvasive monitoring method and monitoring device for cerebral blood oxygen |
CN112043287B (en) * | 2020-09-30 | 2021-07-20 | 重庆大学 | Noninvasive monitoring method and monitoring device for cerebral blood oxygen |
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C14 | Grant of patent or utility model | ||
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CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20121114 Termination date: 20130405 |