CN202505854U - Dialyzate cleaning device and dialysis device with same - Google Patents

Dialyzate cleaning device and dialysis device with same Download PDF

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Publication number
CN202505854U
CN202505854U CN2011205555094U CN201120555509U CN202505854U CN 202505854 U CN202505854 U CN 202505854U CN 2011205555094 U CN2011205555094 U CN 2011205555094U CN 201120555509 U CN201120555509 U CN 201120555509U CN 202505854 U CN202505854 U CN 202505854U
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China
Prior art keywords
dialysis solution
dialysis
solution
valve
cleanout fluid
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CN2011205555094U
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Chinese (zh)
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佐藤政昭
柚木雅之
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Med Tech Inc
Meditech KK
Asahi Kasei Medical Co Ltd
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Meditech KK
Asahi Kasei Medical Co Ltd
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Abstract

The utility model belongs to the technical field of cleaning disinfection devices of medical equipment, and relates to a dialyzate cleaning device. The dialyzate cleaning device comprises at least one cleaning solution providing part and a cleaning sleeve, wherein the cleaning sleeve comprises a cleaning solution inlet which is used to be connected with the cleaning solution providing part, and can be connected with a cleaning end port of a dialysis device in a mode of accommodating the cleaning end port of the dialysis device. The utility model also discloses the dialysis device with the dialyzate cleaning device. By the dialyzate cleaning device and the dialysis device with the dialyzate cleaning device, a stock solution suction part and a connecting part between the stock solution suction part and the cleaning device can be thoroughly cleaned, and cross infection can be prevented.

Description

Dialysis solution rinser and have the dialysis apparatus of this dialysis solution rinser
Technical field
This utility model relates to a kind of cleaning sterilizing device of medical apparatus and instruments, relates in particular to a kind of dialysis solution rinser and has the dialysis apparatus of this dialysis solution rinser.
Background technology
If nephrotic's renal function completely loses or only some works; Its intravital electrolyte begins disequilibrium; In addition, refuse is assembled in blood, rather than along with urine excretes together; Can cause very big infringement to patient's life like this, thereby need carry out dialysis treatment the nephrotic.Employed haemodialysis control unit comprises dialyser and dialysis apparatus in the dialysis treatment; Make the dialyser by semipermeable membrane processed of blood in the concrete therapeutic process through letting small-molecule substance (like electrolyte, micromolecule kidney property toxin) passes through; Make the side of blood at film, dialysis solution is at the opposite side of film, and the solution of both sides is through disperse, osmosis; Be that solute is by the high low side flow of a side direction concentration of concentration; Let the micromolecule kidney property toxin in the blood may penetrate in the dialysis solution, electrolyte also can reach balance through osmosis, thereby reaches the purpose of blood purification.And dialysis apparatus is to be used for the dialysis solution for preparing is provided to dialyser, and the corollary equipment that used useless dialysis solution is reclaimed and discharges from dialyser.
Generally; For preventing cross infection; The pipeline of dialyser adopts disposable pipeline; And parts such as each pipeline in the dialysis apparatus and storage container be because of can't adopting Bullet structure, must be in each back of using to residuing in ducted protein, fat and deleterious metabolite and clean and sterilizing.Prior art will be provided with special cleaning end interface (being generally the stock solution drawing section of inserting former liquid container) usually in dialysis apparatus; When each dialysis treatment finishes; Change the stock solution drawing section on the interface that is connected to rinser from former liquid container; Through the stock solution suction passage with cleaning solution supplying in the fluid loop of dialysis apparatus, thereby cleanout fluid is also circulated in dialysis apparatus, to reach the purpose of cleaning.
But in said method, have cleaning halfway problem, the especially outside of stock solution drawing section in the junction of stock solution drawing section and rinser, belong to the zone that cleanout fluid can't arrive.And each the cleaning all is directly connected to the stock solution drawing section on the rinser interface, because this interface self can have antibacterial or virus etc., thereby the seam of stock solution drawing section also can be contaminated.Thereby, use again if will clean halfway stock solution drawing section, can pollute stock solution, cause different patients' cross infection, influence the dialysis treatment effect.
In addition, that common dialysis solution rinser also has is independent, as the driving pump of cleanout fluid driving device, and cost is higher like this, also can't realize miniaturization.
The utility model content
Therefore the purpose of this utility model is to provide a kind of and cleans thoroughly, can not cause the dialysis solution rinser of cross infection and have the dialysis apparatus of this dialysis solution rinser.
The further purpose of this utility model is to provide that a kind of cost is lower, the dialysis solution rinser of miniaturization and have the dialysis apparatus of this dialysis solution rinser.
For realizing above-mentioned purpose, the technical scheme of this utility model is:
A kind of dialysis solution rinser; Comprise that at least one cleanout fluid provides portion; Also comprise and clean cover, said cleaning cover comprises and is used for the filter washing water inlet that is connected with the said cleanout fluid portion of providing, and can be connected with the cleaning end interface of this dialysis apparatus with the mode of the cleaning end interface of taking in dialysis apparatus.
In the present technique scheme; Adopted and can take in the cleaning cover that cleans end interface, like this, in concrete cleaning process; Cleaning whole being soaked in of end interface cleans in the cleanout fluid that overlaps; Can so that clean end interface inside and outsidely be cleaned totally simultaneously, thereby clean comparatively thoroughly, can not cause the cross infection between different patients yet.
The said cleanout fluid portion of providing comprises that cleanout fluid provides container and the valve that provides container to be connected with this cleanout fluid; The said cleanout fluid portion of providing is a plurality of; After each said cleanout fluid provides the valve of portion all to have an end and other cleanout fluid to provide this end of the valve of portion to interconnect, be connected with the said filter washing water inlet of said cleaning cover.
As the improvement of technique scheme, when cleanout fluid when being multiple, adopt the structure of above-mentioned that kind, can be so that the shared pipeline of each road cleanout fluid can make whole device realize miniaturization.
Said cleanout fluid provides container to comprise to be equipped with first cleanout fluid of medicinal liquid to provide container and second cleanout fluid that is equipped with acid solution that container is provided, and said cleaning cover comprises that the first stock solution A cleans cover and cleans with the second stock solution B and overlap.
The lower end or the middle part of said cleaning cover is located in the filter washing water inlet of said cleaning cover.Such structure makes that cleanout fluid is sailed against the current from the bottom to top in the cleaning process, makes cleaning performance better.
Also comprise and be used for providing the cleanout fluid in the container to suck the cleanout fluid driver part that cleans end interface cleanout fluid via cleaning cover.In addition, when cleaning end, also can utilize the cleanout fluid driver part with the ducted cleanout fluid water displacement of cleanout fluid.
Said driver part is a piston pump.In the present technique scheme, adopted piston pump, can realize the purpose that cleanout fluid is quantitatively drawn as drive source.The amount of the cleanout fluid of particularly, being drawn equals the volume-variation of the work chamber in the pumping cylinder.So the operation through the piston in the control piston pump accurately can make the absorption amount of cleanout fluid reach point-device degree.
A kind of dialysis apparatus; Comprise the dialysis solution accent liquid device, dialysis solution stowage arrangement and the dialysis solution driving device that connect successively; This dialysis solution driving device offers dialyser with the dialysis solution in the dialysis solution stowage arrangement; And the used dialysis solution of dialyser turned back to the dialysis solution stowage arrangement, said dialysis apparatus also comprises like each described dialysis solution rinser in above-mentioned.
The dialysis apparatus of present technique scheme has been owing to adopted above-mentioned dialysis solution rinser, thereby comparatively thorough to cleaning of each module of dialysis apparatus inside, also can not cause the cross infection between different patients.
The cleaning end interface of said dialysis apparatus is dialysis solution and transfers the stock solution drawing section that is used to draw stock solution on the liquid device.As the improvement of technique scheme, adopt the stock solution drawing section as cleaning end interface, can be so that cleanout fluid utilizes in the dialysis apparatus unborn dialysate circuit that the various piece of whole dialysis apparatus is cleaned.
A kind of dialysis apparatus; Comprise the dialysis solution accent liquid device, dialysis solution stowage arrangement and the dialysis solution driving device that connect successively; This dialysis solution driving device offers dialyser with the dialysis solution in the dialysis solution stowage arrangement; And the used dialysis solution of dialyser turned back to the dialysis solution stowage arrangement; Said dialysis apparatus also comprises like above-mentioned dialysis solution rinser, and utilizes the raw liquor pump of absorption dialysis solution stock solution that said dialysis solution transfers liquid device as the cleanout fluid driver part of said dialysis solution rinser.
As the further improvement of this utility model, make rinser with existing drive source in the dialysis apparatus, can reduce the cost of rinser greatly, realize miniaturization.In addition, when cleaning end, also can utilize the cleanout fluid driver part with the ducted cleanout fluid water displacement of cleanout fluid.
Said cleanout fluid driver part is the piston pump that is used to draw stock solution.When technique scheme is done further to improve,, can reach the purpose of the liquid measure of the cleanout fluid that accurate control draws so preferably with the drive source of piston pump as cleanout fluid.
Said dialysis solution transfers liquid device also to comprise: the water pressurization that the outside is supplied with is also delivered to the liquid-feeding pump of dialysis solution stowage arrangement with the mixed liquor of the water of pressurization and cleanout fluid, and said dialysis solution driving device comprises delivers to the driving pump in the dialysis solution driving device with the water of being supplied with by the dialysis solution stowage arrangement and the mixed liquor of cleanout fluid.
Liquid-feeding pump is convenient to the water of external world's supply (hot water of perhaps transferring liquid device to provide at dialysis solution) is delivered to the dialysis solution stowage arrangement, thereby has satisfied the water demand in the cleaning process.Simultaneously, be provided with driving pump, also be convenient to the cleanout fluid in the dialysis solution stowage arrangement is delivered to the dialysis solution driving device.
This utility model compared with prior art has following advantage and beneficial effect.In the dialysis solution rinser of this utility model; Adopted and can take in the cleaning cover that cleans end interface, like this, in concrete cleaning process; Cleaning whole being soaked in of end interface cleans in the cleanout fluid that overlaps; Can so that clean end interface inside and outsidely be cleaned totally simultaneously, thereby clean comparatively thoroughly, can not cause the cross infection between different patients yet.And the dialysis apparatus with this dialysis solution rinser of this utility model adopts the stock solution drawing section as cleaning end interface; Can be so that cleanout fluid utilizes in the dialysis apparatus unborn dialysate circuit that the various piece of whole dialysis apparatus is cleaned; Make rinser utilize existing drive source in the dialysis apparatus simultaneously; Can reduce the cost of rinser greatly, realize miniaturization.Thereby cost is lower, can realize miniaturization.
Description of drawings
Fig. 1 is the system flow block diagram of whole dialysis apparatus and dialyser mating reaction;
Fig. 2 transfers the system flow chart of liquid device for dialysis solution;
Fig. 3 is the simple functional schematic that above-mentioned dialysis solution is made parts;
Fig. 4 is the system flow chart of dialysis solution stowage arrangement;
Fig. 5 is the operation principle sketch of constant flow rate valve;
Fig. 6 is the system flow chart of dialysis solution driving device;
Fig. 7 is the system flow chart of dialysis solution rinser;
Fig. 8 is the total system flow chart of dialysis apparatus.
The specific embodiment
Below, according to accompanying drawing the application is at length explained.
Embodiment
The application's dialysis apparatus is used for that concentration is moderate, the dialysis solution of stability of flow for dialyser 8 provides; And dialyser 8 used dialysis solution are reclaimed; In addition; Also the moisture that should discharge as urine in patient's body is removed (water pump that removes through being used for extracting from the useless dialysis solution of giving back a certain amount of useless dialysis solution realizes, the said a certain amount of amount that is equivalent to the urine that dialyser gives from blood) with the mode of dialysis solution.Fig. 1 is the system flow block diagram of whole dialysis apparatus and dialyser 8 mating reactions.As shown in fig. 1; The dialysis apparatus of present embodiment comprises: the dialysis solution that connects is successively transferred liquid device 11, dialysis solution stowage arrangement 3 and dialysis solution driving device 4; In addition; Dialysis solution stowage arrangement 3 also is connected with dialysis solution discharger 6, and the running of whole dialysis apparatus leans on the cooperation of each part mentioned above to accomplish.Dialysis solution driving device 4 is connected with dialyser 8 again; In addition, dialysis apparatus also comprises dialysis solution rinser 5, in the present embodiment; Preferred this dialysis solution rinser 5 transfers liquid device 11 to link to each other with the dialysis solution that is positioned at the upper reaches of whole system, to reach the effect that can clean whole system better.Particularly, dialysis solution accent liquid device 11 is prepared continuously has certain density dialysis solution, and offers dialysis solution stowage arrangement 3.Dialysis solution stowage arrangement 3 offers dialysis solution driving device 4 with this dialysis solution for preparing, and by dialysis solution driving device 4 this dialysis solution is offered dialyser 8.In addition, dialysis solution stowage arrangement 3 also reclaims the used dialysis solution that is returned by dialysis solution driving device 4, and is discharged to the outside via dialysis solution discharger 6.Be that dialysis solution driving device 4 is relay portion of dialyser 8 and dialysis solution stowage arrangement 3, and it also provide power for dialysis solution in intrasystem circulation as the drive source that dialysis solution is flowed.And dialysis solution rinser 5 is used for after dialysis treatment carries out preceding or carries out, and whole dialysis apparatus inside is cleaned.
Next respectively each concrete module is introduced.
I, dialysis solution are transferred liquid device 11:
Be illustrated in figure 2 as dialysis solution and transfer the system flow chart of liquid device 11.As shown in Figure 2, this dialysis solution transfers liquid device 11 to comprise the controlled water supply part 1 and the dialysis solution making parts 2 of switching of connection successively.
1, the water supply part 1:
Water supply part 1 is used to whole dialysis apparatus purifying waste water of uniform temperature is provided.As shown in Figure 2; This water supply part 1 according to the direction of current, be from upstream to downstream; Comprise successively: give liquid filter 101, air relief valve 102, valve V9, heat exchanger 103, heater 104, temperature control critesistor 105, as liquid-feeding pump 107, the deaerating tank 108 of the drive source of whole water supply part 1, more than each element connect through first pipeline 111; In addition, (the operating pressure value is set at 1.1kgf/cm between the outlet of the upper reaches of heater 104 inlet and deaerating tank 108, also to be connected with feeding overflow valve 110 through circulating line 109 2); On heater 104, also be provided with the anti-dry pick off (not shown) that is used to prevent dry combustion method, in the choke manifold 106 of part between temperature control critesistor 105 and liquid-feeding pump 107 on first pipeline 111 for the water that imports in the liquid-feeding pump 107 is outgased.Wherein, What need supplementary notes is; The water pressurization that liquid-feeding pump 107 is in fact not only supplied with the outside is also delivered to dialysis solution and is made parts 2, and the impetus that is also just producing owing to the formation on this current road is made the dialysis solution for preparing in the parts 2 with dialysis solution and delivered to dialysis solution stowage arrangement 3.In addition; In technique scheme; Be the structure that degassing parts are set on the pipeline at liquid-feeding pump 107 place, the degassing parts here comprise be located at liquid-feeding pump 107 upstream sides, be used for the choke manifold 106 that the water that are directed in the liquid-feeding pump 107 are outgased and be located at deaerating tank 108 liquid-feeding pump 107 downstreams, that be used to remove the gas that is contained in the water of deriving from liquid-feeding pump 107.
In addition, the switching of this water supply part 1 relies on valve V9 to realize., in water supply part 1, form a partial circulation stream here, promptly external water source gets into circulating line 109 through heater 104, choke manifold 106, liquid-feeding pump 107, deaerating tank 108 backs successively, after this, imports heater 104 again.In above-mentioned example; The circulation stream comprises circulating line 109 and connects the stream that the back forms successively by heater 104, choke manifold 106, liquid-feeding pump 107, deaerating tank 108; But the set-up mode of each parts is not limited thereto in the circulation stream, for example can also be with the side in the degassing parts, liquid-feeding pump 107, the heater 104 or is located at the structure on the circulating line 109 in many ways.Part parts in the circulation stream also can omit, and for example can comprise circulating line 109, above-mentioned liquid-feeding pump 107, heater 104 or comprise circulating line 109, above-mentioned liquid-feeding pump 107, degassing parts.
In addition, the order of placement of above-mentioned each element is not limited to this, but will guarantee that at least deaerating tank 108 is located at liquid-feeding pump 107 downstream, choke manifold 106 is positioned at liquid-feeding pump 107 upper reaches.In addition; Above-mentioned each element also can be deleted according to the needs of reality; Also can not need 103 pairs of water of heat exchanger to carry out preheating and directly water is heated; Water supply part 1 even can include only first pipeline 111, and the water of directly outside being supplied with does not add the dialysis solution that offers of any processing and makes parts 2, makes the purpose that parts 2 provide the water source as long as promptly can be reached for dialysis solution.Such conversion all drops within the application's the protection domain.
Particularly, supply with from the outside through purifying or after comparatively the water of cleaning gets into first pipeline 111, through giving after liquid filter 101 carries out purification filtering, impurity or foreign body are removed; Get into air relief valve 102 it is reduced pressure, make it become authorized pressure, carry out preheating (the used dialysis solution that the thermal source of heat exchanger is stated after being preferably by heat exchanger 103 again through post-decompression water; Can certainly select other thermal source), reach after certain temperature, get into heater 104 and carry out further heat temperature raising (monitoring) by 105 pairs of temperature of temperature control critesistor; After this; Get into choke manifold 106, become big process more suddenly, thereby make the hydraulic pressure after choke manifold 106 outlets diminish suddenly than the preceding hydraulic pressure of choke manifold 106 inlets because its caliber experience diminishes suddenly; Dissolved air discharges in the water thereby can make; And further expand, assembling becomes bigger bubble, after pressurizeing through liquid-feeding pump 107 again; Make that in deaerating tank 108 gas that contains in the water is emitted, can obtain having water set point of temperature, comparatively clean.In addition; Owing between the outlet of the upper reaches of heater 104 inlet and deaerating tank 108, also be connected with feeding overflow valve 110 through circulating line 109, like this, the part of the water after deaerating tank 108 degassings flows into circulating line 109; Again behind feeding overflow valve 110; Converge with water, by heater 104 heating, formed a partial cyclic process here once more from heat exchanger 103.In the whole process of preparatory stage before dialysis and dialysis, this cyclic process continues to carry out, and gives follow-up device to be used to provide the satisfactory water of pressure stability and temperature; In addition; Feeding overflow valve 110 is as pressure limiting device, when the pressure in water supply part 1 is excessive, when for example surpassing authorized pressure; Will open automatically, thereby play the effect of pressure limiting, safeguard protection.
2, dialysis solution is made parts 2:
Dialysis solution is made parts 2 and is used to prepare certain density, satisfactory dialysis solution.The stock solution that is used for preparing dialysis solution can be selected for use multiple as required, and this sentences and selects two kinds: the first stock solution A and the second stock solution B are that example comes the preparation of dialysis solution is described.As shown in Figure 2; This dialysis solution is made parts 2 and is comprised: dosing pipeline 202 and be used to draw the raw liquor pump 201 of stock solution ' (the raw liquor pump here be rely on reciprocating member in pumping cylinder, to move back and forth make swept volume alternately increases in the cylinder, dwindle the pump of drawing stock solution); Water supply part 1 links to each other with raw liquor pump 201 ' inlet; The end of the upstream side of dosing pipeline 202 (upstream side that the upper reaches of the flow direction of the liquid of dosing pipeline internal flow is called the dosing pipeline) links to each other with raw liquor pump 201 ' outlet, and the end in downstream is connected to the constant dialysis solution stowage arrangement 3 of volume (omitting among this figure).On dosing pipeline 202, be arranged at intervals with a plurality of stock solution inlets; And each this stock solution inlet is provided with and is used for the valve of switching station at the stock solution inlet, with the kind of above-mentioned stock solution correspondingly, be that example describes (promptly to be provided with two stock solutions inlets here; Its number also can be for a plurality of; In general, the kind of its number and stock solution is corresponding each other), promptly the stock solution inlet comprises first stock solution A inlet, 203 and second stock solution B inlet 204; Be boundary then, can dosing pipeline 202 be divided into the first dosing pipeline 205, the second dosing pipeline 206 and the 3rd dosing pipeline 207 with this two stock solutions inlet.In addition; This dialysis solution is made parts 2 and is also comprised: the first stock solution A container 210, the second stock solution B container 220; The first stock solution A suction passage 211, the second stock solution B suction passage 221; The first stock solution A container 210 is connected in first stock solution A inlet, 203, the second stock solution B containers 220 through the first stock solution A suction passage 211 and is connected in second stock solution B inlet 204 through the second stock solution B suction passage 221.In addition, on the first stock solution A suction passage 211, also be provided with and be used to realize the first stock solution A valve V11 of 203 switches that enters the mouth, and be used for the filtering first stock solution A filter 213; On the second stock solution B suction passage 221, also be provided with and be used to realize the second stock solution B valve V12 of 204 switches that enters the mouth, and be used for the filtering second stock solution B filter 223.In addition, on the first stock solution A suction passage, 211 ends, also be provided with the first stock solution A drawing section 212 that is used to draw the first stock solution A, it stretches into the first stock solution A container, 210 inside; On the second stock solution B suction passage, 221 ends, also be provided with the second stock solution B drawing section 222 that is used to draw the second stock solution B, it stretches into the second stock solution B container, 220 inside.
In said structure, can also be on the dosing pipeline valve V26 be set and be used for flow-sensint unit 208 that having or not in real time of the ducted dialysis solution for preparing of dosing detected, judges near a side of dialysis solution stowage arrangement 3.Do like this is for whether the real-time dialysis solution that detects in the dosing pipeline flows continuously, if discontinuous situation will be warned in time.In addition, water supply part 1 and raw liquor pump 201 ' between also be connected with flow adjustment choke manifold 209 and valve V10.Need to prove in addition; If be the direction that is from upstream to downstream from raw liquor pump 201 ' on the establishing liquid pipeline 202 to the direction of dialysis solution stowage arrangement 3; The stock solution inlet at the then upper reaches and raw liquor pump 201 ' between spacing should make when utilizing the various stock solution of raw liquor pump 201 ' absorption; Stock solution inlet from the upper reaches get into stock solution in the dosing pipeline can not enter into raw liquor pump 201 ', and the spacing between said each stock solution inlet is set at: make utilize raw liquor pump 201 ' various stock solutions of absorptions after, can not contact between each stock solution in each stock solution inlet entering dosing pipeline 202.Particularly; Raw liquor pump 201 ' outlet is set at the spacing between the stock solution inlet 203 at the above-mentioned upper reaches: when utilizing raw liquor pump 201 ' elder generation when the stock solution inlet at these upper reaches is drawn stock solution, back from other stock solutions inlet absorption stock solutions; After all imbibitions operation is accomplished, certainly the stock solution that sucks of the stock solution inlet at these upper reaches can not get into raw liquor pump 201 '; And the spacing between each stock solution inlet is set at: when the stock solution inlet that utilizes raw liquor pump 201 ' elder generation beyond the stock solution inlet at these upper reaches is drawn the stock solution inlet absorption stock solution that stock solution, back self-alignment swims on it, can in the dosing pipeline, not come in contact between the various stock solutions.
Next, the supply with water is that example explains that how the partially liq stream in the dialysis solution making parts 2 forms, and promptly works as shut off valve V11, V12; When opening valve V10, V26; Water uniform temperature, clean was arranged after inflow-rate of water turbine adjustment choke manifold 209 (higher limit of adjustment discharge) is carried out the flow adjustment from what water supply part 1 was handled, through valve V10, and from raw liquor pump 201 ' the left side inlet get into; Here; Preferred raw liquor pump 201 ' be piston pump 201, the water that then gets into piston pump 201 enters into dosing pipeline 202 from the outlet of the right side of piston pump 201, further enters in the dialysis solution stowage arrangement 3.And when needs are drawn each stock solution, only need shut off valve V10, valve V26, and open corresponding valve V11 and/or V12, make piston pump 201 actions, just can stock solution A and/or stock solution B be drawn in the middle of the dosing pipeline 202.
Specify the process for preparation of dialysis solution below.As shown in Figure 2, water uniform temperature, clean was arranged after inflow-rate of water turbine adjustment choke manifold 209 (higher limit of adjustment discharge) is carried out the flow adjustment through what water supply part 1 was handled, enter in the piston pump 201 through valve V10.Fig. 3 is the simple functional schematic that above-mentioned dialysis solution is made parts 2.Next come the process for preparation of each stock solution is elaborated with reference to figure 2, Fig. 3.This process comprises the steps:
(1) with this first dosing pipeline 205, the second dosing pipeline 206, the 3rd dosing pipeline 207 fills with water all, just make whole dosing pipeline 202 be full of water.
Particularly, open valve V9, V10, V26, shut off valve V11, V12 will be full of whole dosing pipeline 202 and dialysis solution stowage arrangement 3 from the water of water supply part 1, can before the whole system running, the air of internal system all be removed like this.
(2) the first stock solution A and the second stock solution B with ormal weight is drawn into respectively in the first dosing pipeline 205 and in the second dosing pipeline 206.
Promptly; The water source of raw liquor pump 201 ' inlet is closed (being shut off valve V10); Make raw liquor pump 201 ' in reciprocating member (when raw liquor pump is piston pump or plunger displacement pump; Reciprocating member is for example piston or plunger) to direction motion, the first stock solution A, the second stock solution B are drawn in the dosing pipeline 202 away from raw liquor pump 201 ' outlet.
This suction process both can be carried out the absorption of the first stock solution A and the second stock solution B simultaneously; Also can draw the first stock solution A earlier, draw the second stock solution B again; Also can draw the second stock solution B earlier, draw the first stock solution A again.Below to draw the first stock solution A earlier; Drawing the second stock solution B again is that example describes; Because drawing the class of operation to raw liquor pump 201 ' parts such as (piston pumps 201) of mode, all the other seemingly specifically can analogize, so omit detailed description here to other situation with reference to following step.
Be that above-mentioned steps (2) in turn includes the following steps:
(2-1) the first stock solution A with ormal weight sucks in the first dosing pipeline 205.
Open valve V11; Shut off valve V10, V12, V26; The below of piston in Fig. 2 of piston pump 201 pulled ormal weight, will the first stock solution A of ormal weight be drawn in the first dosing pipeline 205 through the first stock solution A drawing section 212, the first stock solution A suction passage 211, first stock solution A inlet 203.The ormal weight that above-mentioned piston pulls is to choose desired value according to parameters such as different patients' requirement and concentration.In addition; The piston of piston pump 201 is pulled ormal weight downwards; This ormal weight will guarantee that also the first stock solution A is inhaled in the first dosing pipeline 205 between first stock solution A inlet 203 and piston pump 201 outlets just; And be not inhaled in the piston pump 1, so the first dosing pipeline 205 will guarantee enough length.
(2-2) the second stock solution B with ormal weight sucks in the second dosing pipeline 206.
Promptly; Open valve V12; Shut off valve V10, V11, V26 pull ormal weight downwards again with the piston of piston pump 201, and the second stock solution B that will make ormal weight is drawn in the second dosing pipeline 206 through the second stock solution B drawing section 222, the second stock solution B suction passage 221, second stock solution B inlet 204.With likewise above-mentioned, in this process, the ormal weight that piston pulls also is to choose desired value according to parameters such as different patients' requirement and concentration.In addition; The piston of piston pump 201 is pulled ormal weight downwards; This ormal weight will guarantee that also the second stock solution B is inhaled in the second dosing pipeline 206 between first stock solution A inlet, the 203 and second stock solution B inlet 204 just; The second dosing pipeline 206 (that is, can not be inhaled in the first dosing pipeline 205 and the first stock solution A suction passage 211) in the first stock solution A inlet 203 and be not inhaled into, so will guarantee enough length.Simultaneously, in the time of owing to the absorption second stock solution B, the first stock solution A also is moved to the left in the first dosing pipeline 205 simultaneously, is easier to be sucked in the piston pump 201.To sum up, at this moment, piston pump 201 outlet should be set as follows with the spacing between the first stock solution A inlet, promptly after utilizing piston pump 201 to draw the first stock solution A, the back absorption second stock solution B earlier, the first stock solution A can not get into piston pump 201.And the spacing between first stock solution A inlet and the second stock solution B inlet is provided with as follows; Promptly after utilizing piston pump 201 to draw the first stock solution A, the back absorption second stock solution B earlier; The second stock solution B can not get into first stock solution A inlet 203 (even perhaps through first stock solution A inlet 203; Enter in the first dosing pipeline 205, also do not contact) with the first stock solution A.
(3) afterwards through above-mentioned steps (2); The first stock solution A and the second stock solution B are drawn into respectively in the first dosing pipeline 205 and the second dosing pipeline 206; And diluted to a certain extent by the water that had originally in the dosing pipeline 202; Proceed last step then: this first dosing pipeline 205, the second dosing pipeline 206, the 3rd dosing pipeline 207 are supplied with water, the second stock solution B and the water drawn in the first stock solution A that drawn in the liquid distribution pipe road 205 of winning, the second dosing pipeline 206 are supplied in the dialysis solution stowage arrangement 3.
This step is that the second stock solution B and the first stock solution A are successively sent into the process in the dialysis solution stowage arrangement 3.Particularly; Before valve V10 opens, the piston of piston pump 201 is got back to carried out above-mentioned steps (2) assigned position before, open valve V9, V10, V26 then; Shut off valve V11, V12 flow in dosing pipeline 202, the dialysis solution stowage arrangement 3 water from water supply part 1.And the impetus through water flows; Just can the first stock solution A that be inhaled in the first dosing pipeline 205 be brought into respectively within the constant dialysis solution stowage arrangement 3 of volume with the second stock solution B that is inhaled in the second dosing pipeline 206; Thereby in dialysis solution stowage arrangement 3, obtain having the dialysis solution (mixed liquor of the first stock solution A+, the second stock solution B+ water) of finite concentration and volume; Meanwhile, whole dosing pipeline 202 all is full of water once more, gets back to step (1); So back and forth each step can continuously be prepared dialysis solution.
As stated, the compound method of the application's dialysis solution is not limited to said process, and other change also can be arranged; For example also can draw the second stock solution B earlier, draw the first stock solution A again, perhaps draw the two simultaneously; Because each process is similar substantially, can analogize, and repeats no more here.But wherein be noted that especially; When utilizing piston pump 201 to draw the second stock solution B, the back absorption first stock solution A earlier; Spacing between the first stock solution A enters the mouth and the second stock solution B enters the mouth should be set as follows, and promptly when utilizing piston pump 201 to draw the second stock solution B, the back absorption first stock solution A earlier, the second stock solution B can not get into the first stock solution A and enter the mouth 203 (perhaps; Even through first stock solution A inlet 203, contact only otherwise with the first stock solution A get final product).And piston pump 201 outlet is provided with the spacing between the first stock solution A inlet as follows, promptly after utilizing piston pump 201 to draw the second stock solution B, the back absorption first stock solution A earlier, the first stock solution A can not get into piston pump 201.
In addition, be provided with special dialysis solution zone in the above-mentioned dialysis solution stowage arrangement 3, be used for depositing the above-mentioned dialysis solution for preparing.And in each work process, the summation of the volume of the dialysis solution of being made up of this first stock solution A, the second stock solution B and water equates with the volume of dialysis solution stowage arrangement 3.
In the dosing method of present embodiment,, thereby earlier it is carried out dialysis solution stowage arrangement 3 in, mixing after certain dilution again, can avoid different stock solution to mix back redilution and the variety of problems that produces through the absorption first stock solution A and the second stock solution B of timesharing.And can prepare the dialysis solution of desired concn and amount continuously according to the needs of practical operation, simple.
Transferring the work process of liquid device 11 in the face of whole dialysis solution down describes.The dialysis solution dosing method that is present embodiment comprises the steps:
(a) preparation process is opened valve V9, and shut off valve V10, V11, V12, V26 make water supply part 1 operate, thereby produce the water of the cleaning of uniform temperature.Detailed operation situation about this step was introduced in above-mentioned part in detail, so repeat no more here.Certainly, this step turns round when being not limited only to prepare dialysis solution, can in whole dialysis procedure, be in the operation phase all the time so that whenever can for follow-up device for example dialysis solution stowage arrangement 3 water source is provided.
(b) dialysis solution preparation steps, owing to when introducing dialysis solution making parts, preparation steps was carried out detailed description, repeats no more here here.
To sum up, this dialysis solution transfers liquid device 11 under the prerequisite that makes 1 running of water supply part, repeats the dialysis solution preparation steps of (b), thereby constantly is dialysis solution stowage arrangement 3 preparation finite concentration and a certain amount of dialysis solution.
In addition, in the present embodiment, be to be the explanation that example is carried out with two kinds of stock solutions,, repeat no more owing to can analogize for the preparation of two or more stock solution by present embodiment here.Simultaneously, on concrete structure, also be not limited thereto, dialysis solution transfers each element in the liquid device 11 also can delete according to the needs of reality.In addition, the choosing of raw liquor pump also can be adopted other the pump except piston pump, as long as can reach the purpose that can draw stock solution.In addition, also can omit the stock solution drawing section, and directly the stock solution suction passage inserted the stock solution internal tank.
II, dialysis solution stowage arrangement 3
The dialysis solution stowage arrangement of present embodiment comprises at least one chamber, and each chamber interior is equipped with the next door (preferred flexible next door) that this chamber is separated into dialysis solution zone and waste liquid zone; The dialysis solution that can ccontainingly prepare in the dialysis solution zone can ccontaining used dialysis solution in the waste liquid zone; Thereby and the next door can move freely under the effect of external force in chamber dialysis solution zone and the regional volume of waste liquid are changed; In addition; The dialysis solution stowage arrangement also comprises: be connected with the dialysis solution zone, be used to make the dialysis solution zone dialysis solution for preparing to be preserved or the dialysis solution passage of liquor charging, and be connected with the waste liquid zone, be used to make the waste liquid zone used dialysis solution (the following waste liquid of also claiming) to be reclaimed or the waste fluid channel of discharge opeing.In addition, when the next door was flexible next door, it can stretch under the effect of external force and to dialysis solution zone one side, or waste liquid zone one side shifting, thereby dialysis solution zone and the regional volume of waste liquid are changed.
When dialysis solution is preserved in the dialysis solution zone of each chamber, its waste liquid zone effluent discharge, when dialysis solution was seen in the dialysis solution zone of each chamber off, waste liquid was reclaimed in its waste liquid zone; Above-mentioned each chamber is grouped into the first chamber group and the second chamber group; When dialysis solution is preserved in the dialysis solution zone of the first chamber group; Dialysis solution is seen in the dialysis solution zone of the second chamber group off; When waste liquid is reclaimed in the waste liquid zone of the first chamber group, the waste liquid zone effluent discharge of the second chamber group, the summation of the dischargeable capacity of the chamber of the participation work process of this first chamber group equates with the summation of the dischargeable capacity of the chamber of the participation work process of the second chamber group.In each work process, these two working groups are mainly used in and realize following two functions: 1. be used for seeing the dialysis solution for preparing off, reclaiming used dialysis solution (the following waste liquid of also claiming) from dialyser to dialyser; 2. be used for useless dialysis solution is expelled to the dialysis solution discharger, be used to preserve the dialysis solution for preparing of transferring liquid device from dialysis solution.This first chamber group and the second chamber group are in per two adjacent work process, and circulation realizes above-mentioned two functions.
Wherein, the number of chamber can be selected according to actual needs.In addition,, two passes both can be set be used for realizing storage and liquor charging respectively, that is, can carry out above-mentioned two processes simultaneously dialysis solution about the dialysis solution passage; Also a dialysis solution passage can only be set, storage and liquor charging process to dialysis solution are realized in timesharing ground.The setting of waste fluid channel and dialysis solution channel types seemingly, likewise can be simultaneously or timesharing ground used dialysis solution is reclaimed or discharge opeing.Wherein, two passes specifically is provided with as follows: above-mentioned dialysis solution passage comprises two passages, i.e. dialysis solution liquor charging passage 309 and dialysis solution storage passage 310; And waste fluid channel also comprises two passages, i.e. waste liquid recovery approach 319 and waste liquid apocenosis passage 320.On dialysis solution liquor charging passage 309, dialysis solution storage passage 310, waste liquid recovery approach 319, waste liquid apocenosis passage 320, also be respectively equipped with dialysis solution liquor charging valve, dialysis solution storage valve, waste liquid recovery valve, the waste liquid tapping valve of control respective channel break-make simultaneously.The setting of above-mentioned each valve is the break-make for the ease of each passage, certainly, also can valve be set and adopt other mode to realize the break-make of each passage.The annexation of above-mentioned each passage is following: dialysis solution liquor charging passage 309 1 ends link to each other with the dialysis solution zone of each chamber respectively, and the dialysis solution liquor charging part (afterwards stating dialysis solution feeding portion) of the other end and dialysis solution driving device is connected; Dialysis solution storage passage 310 1 ends link to each other with the dialysis solution zone of each chamber respectively, and the other end transfers the dialysis solution dosing pipeline 202 of liquid device 11 to be connected with dialysis solution; Waste liquid recovery approach 319 1 ends link to each other with the waste liquid zone of each chamber respectively, and the dialysis solution of the other end and dialysis solution driving device 4 returns liquid part (afterwards state dialysis solution and give back portion) and is connected; Waste liquid apocenosis passage 320 1 ends link to each other with the waste liquid zone of each chamber respectively, and the other end is connected with dialysis solution discharger 6.
Below be that example describes to select two chambers (belonging to the first chamber group and the second chamber group respectively), dialysis solution passage and waste fluid channel to include two passages, other situation can be analogized according to this example, repeats no more here.
Be illustrated in figure 4 as the system flow chart of dialysis solution stowage arrangement 3.As shown in Figure 4, this dialysis solution stowage arrangement 3 comprises first chamber 301 and second chamber 311 (promptly the dischargeable capacity of the chamber of the participation work process of the first chamber group equates with the dischargeable capacity of the chamber of the participation work process of the second chamber group) that volume equates.Be provided with under external force movably first next door 302 in first chamber 301, it is divided into disconnected first dialysis solution zone 303 and first waste liquid regional 304 with first chamber 301; Be provided with under external force movably second next door 312 in second chamber 311, it is divided into disconnected second dialysis solution zone 313 and second waste liquid regional 314 with second chamber 311.And can deposit the dialysis solution for preparing in 303 and second dialysis solution zone, first dialysis solution zone 313, can deposit used dialysis solution in 304 and second waste liquid zone, first waste liquid zone 314.
Ground matches with the structure of above-mentioned two chambers; Be provided with as follows again: dialysis solution liquor charging passage 309 comprises the first dialysis solution liquor charging passage 305 and the second dialysis solution liquor charging passage 315, can the dialysis solution that prepare in the dialysis solution zone be delivered to dialyser 8 through it; Dialysis solution storage passage 310 comprises first dialysis solution storage passage 306 and second dialysis solution storage passage 316, through it dialysis solution of transferring liquid device 11 to prepare by dialysis solution is preserved in the dialysis solution zone; Waste liquid recovery approach 319 comprises the first waste liquid recovery approach 307 and the second waste liquid recovery approach 317, can dialyser 8 used dialysis solution be recycled in the waste liquid zone through it; Waste liquid apocenosis passage 320 comprises the first waste liquid apocenosis passage 308 and the second waste liquid apocenosis passage 318, can the used dialysis solution that reclaim in the waste liquid zone be discharged outside the dialysis solution stowage arrangement through it.In addition, dialysis solution liquor charging valve comprises: be located at the first liquor charging valve V2 and the second liquor charging valve V7 on the first dialysis solution liquor charging passage 305 and the second dialysis solution liquor charging passage 315 respectively; Dialysis solution storage valve comprises the first storage valve V1 and the second storage valve V8 that is located at respectively on first dialysis solution storage passage 306 and second dialysis solution storage passage 316; The waste liquid recovery valve comprises the first recovery valve V4 and the second recovery valve V5 that is located at respectively on the first waste liquid recovery approach 307 and the second waste liquid recovery approach 317, and the waste liquid tapping valve comprises the first tapping valve V3 and the second tapping valve V6 that is located at respectively on the first waste liquid apocenosis passage 308 and the second waste liquid apocenosis passage 318.
Specify the connection situation of each parts below: the first dialysis solution liquor charging passage, 305 1 ends are connected with first dialysis solution zone 303, and the dialysis solution liquor charging part (afterwards stating dialysis solution feeding portion) of the other end and dialysis solution driving device is connected; The second dialysis solution liquor charging passage, 315 1 ends are connected with second dialysis solution zone 313, and the dialysis solution liquor charging part (afterwards stating dialysis solution feeding portion) of the other end and dialysis solution driving device is connected; First dialysis solution storage passage, 306 1 ends are connected with first dialysis solution zone 303, and the other end transfers the dialysis solution dosing pipeline 202 of liquid device 11 to be connected with dialysis solution; Second dialysis solution storage passage, 316 1 ends are connected with second dialysis solution zone 313, and the other end transfers the dialysis solution dosing pipeline 202 of liquid device 11 to be connected with dialysis solution; The first waste liquid recovery approach, 307 1 ends are connected with first waste liquid zone 304, and the dialysis solution of the other end and dialysis solution driving device 4 returns liquid part (afterwards state dialysis solution and give back portion) and is connected; The second waste liquid recovery approach, 317 1 ends are connected with second waste liquid zone 314, and the dialysis solution of the other end and dialysis solution driving device 4 returns liquid part (afterwards state dialysis solution and give back portion) and is connected; The first waste liquid apocenosis passage, 308 1 ends are connected with first waste liquid zone 304, and the other end is connected with dialysis solution discharger 6; The second waste liquid apocenosis passage, 318 1 ends are connected with second waste liquid zone 314, and the other end is connected with dialysis solution discharger 6.
In addition; Between waste liquid apocenosis passage 320 and waste liquid recovery approach 319, also be provided with except that water pump 321; Be mainly used in to remove and work as the moisture of getting rid of, being excluded as urine in the human body with the form of useless dialysis solution; But the selection of pump is not limited to this here, also can adopt pump such as ultrafiltrate pump to realize, as long as can reach the purpose of removing dialysis solution.The flow-sensint unit 324 that on dialysis solution liquor charging passage 309, also is provided with flow rate regulating valve 322 and is used to monitor the mobile time of dialysis solution in the dialysis solution liquor charging passage 309.In addition, between this dialysis solution liquor charging passage 309 and waste liquid recovery approach 319, be provided with the constant flow rate valve 323 that is used to regulate the fluid pressure that is applied to flow rate regulating valve 322 two ends., also be not limited thereto here, be located between the outlet and inlet of dialyser as long as guarantee about the position of constant flow rate valve 323.
Concrete storage practice in the face of dialysis solution stowage arrangement 3 is elaborated down.The storage practice of the dialysis solution stowage arrangement 3 of present embodiment may further comprise the steps:
(1) makes second dialysis solution zone 313 of second chamber 311 preserve the dialysis solution for preparing, second waste liquid zone, the 314 interior used dialysis solution of second chamber 311 are discharged; Make first waste liquid zone 304 of first chamber 301 reclaim used dialysis solution, make first dialysis solution zone, the 303 interior dialysis solution that prepare of first chamber 301 deliver to dialyser 8 simultaneously.
(2) make second waste liquid zone 314 of second chamber 311 reclaim used dialysis solution, make second dialysis solution zone, the 313 interior dialysis solution that prepare of second chamber 311 deliver to dialyser 8 simultaneously; Make first dialysis solution zone 303 of first chamber 301 preserve the dialysis solution for preparing, first waste liquid zone, the 304 interior used dialysis solution of first chamber 301 are discharged.
In the process of whole dialysis treatment, alternately carry out above-mentioned two steps repeatedly, thereby carry out the supply of dialysis solution and the recovery of used dialysis solution continuously.
Particularly; In the above-mentioned steps (1), open the second storage valve V8 that is located on second dialysis solution storage passage 316, be located at the second tapping valve V6 on the second waste liquid apocenosis passage 318, be located at the first recovery valve V4 on the first waste liquid recovery approach 307 and be located at the first liquor charging valve V2 on the first dialysis solution liquor charging passage 305; And close the second liquor charging valve V7 that is located on the second dialysis solution liquor charging passage 315, be located at the second recovery valve V5 on the second waste liquid recovery approach 317, be located at the first tapping valve V3 on the first waste liquid apocenosis passage 308, be located at the first storage valve V1 on first dialysis solution storage passage 306; Then transfer the dialysis solution for preparing of the dosing pipeline 202 of liquid device 11, get into via second dialysis solution storage passage 316 in second dialysis solution zone 313 of second chamber 311 from above-mentioned dialysis solution; In this process; Side by side oppress second next door 312 to second waste liquid zone, 314 1 side shiftings; Make second waste liquid zone, 314 interior, in last cycle of operation, preserved, the used dialysis solution of second chamber 311, the dialysis solution discharger of stating after being discharged to via the second waste liquid apocenosis passage 318 6; And in first chamber 301, return the used dialysis solution of liquid part (afterwards state dialysis solution and give back portion) from the dialysis solution of dialysis solution driving device 4, enter into first waste liquid zone 304 of first chamber 301 via the first waste liquid recovery approach 307; In this process; Side by side oppress first next door 302; To first dialysis solution zone, 303 1 side shiftings; Make in the middle of first dialysis solution zone 303, in last cycle of operation dialysis solution that preserved, that prepare, the dialysis solution liquor charging part (afterwards stating dialysis solution feeding portion) that gets into dialysis solution driving devices 4 via the first dialysis solution liquor charging passage 305.In this step; Because the volume of two chambers equates, enter into second chamber 311 second dialysis solution zone 313 the dialysis solution for preparing amount, supply to the amount of the dialysis solution for preparing of dialyser from first dialysis solution zone 303 of first chamber 301, be discharged to the amount of the dialysis solution that uses system outside from second waste liquid zone 314 of second chamber 311 and the amount that reclaims by first waste liquid zone 304 of first chamber 301 from the dialysis solution after the use of dialyser 8 all equal.Thereby reached break-even effect.After being noted that especially that here this step finishes, second next door 312 moves to low order end (second waste liquid zone, 314 ends) from the high order end (second dialysis solution zone, 313 ends) of second chamber 311; First next door 302 moves to low order end (first dialysis solution zone, 303 ends) from the high order end (first waste liquid zone, 304 ends) of first chamber 301.Like this, can guarantee that also the feed liquor amount of second chamber 311 and first chamber 301 and liquid outlet quantity equate, are the volume of second chamber 311 (first chamber 301).
In the above-mentioned steps (2), open the second liquor charging valve V7 that is located on the second dialysis solution liquor charging passage 315, be located at the second recovery valve V5 on the second waste liquid recovery approach 317, be located at the first tapping valve V3 on the first waste liquid apocenosis passage 308 and be located at the first storage valve V1 on first dialysis solution storage passage 306; And close the second storage valve V8 that is located on second dialysis solution storage passage 316, be located at the second tapping valve V6 on the second waste liquid apocenosis passage 318, be located at the first recovery valve V4 on the first waste liquid recovery approach 307 and be located at the first liquor charging valve V2 on the first dialysis solution liquor charging passage 305; Then transfer the dialysis solution for preparing of the dosing pipeline 202 of liquid device 11, get into via first dialysis solution storage passage 306 in first dialysis solution zone 303 of first chamber 301 from above-mentioned dialysis solution; In this process; Side by side oppress first next door 302 to first waste liquid zone, 304 1 side shiftings; Make first waste liquid zone, 304 interior, in last step, preserved, the used dialysis solution of first chamber 301, the dialysis solution discharger of stating after being discharged to via the first waste liquid apocenosis passage 308 6; And in second chamber 311, return the used dialysis solution of liquid part (afterwards state dialysis solution and give back portion) from the dialysis solution of dialysis solution driving device 4, enter into second waste liquid zone 314 of second chamber 311 via the second waste liquid recovery approach 317; In this process; Side by side oppress second next door 312 to second dialysis solution zone, 313 1 side shiftings; Make in second dialysis solution zone 313, in last step dialysis solution that preserved, that prepare, the dialysis solution liquor charging part (afterwards stating dialysis solution feeding portion) that gets into dialysis solution driving devices 4 via the second dialysis solution liquor charging passage 315.
In this step, enter into first chamber 301 first dialysis solution zone 303 the dialysis solution for preparing amount, supply to the amount of the dialysis solution for preparing of dialyser from second dialysis solution zone 313 of second chamber 311, be discharged to the amount of the dialysis solution that uses system outside from first waste liquid zone 304 of first chamber 301 and the amount that reclaims by second waste liquid zone 314 of second chamber 311 from the dialysis solution after the use of dialyser 8 all equal.Thereby reached break-even effect.Be noted that especially here; After this step finishes; First next door 302 moves to high order end (first waste liquid zone, 304 ends) from the low order end of first chamber 301 (first dialysis solution zone, 303 ends), and second next door 312 moves to high order end (second dialysis solution zone, 313 ends) from the low order end (second waste liquid zone, 314 ends) of second chamber 311.Like this, can guarantee that the feed liquor amount of second chamber 311 and first chamber 301 and liquid outlet quantity equate, are the volume of second chamber 311 (first chamber 301).
Say in further detail; In step (1); Second chamber 311 is realized following function: i.e. the dialysis solution for preparing of liquid device 11 is transferred in second dialysis solution in left side zone, 313 storages from dialysis solution; The dialysis solution discharger of stating after the used dialysis solution that second waste liquid zone 314 on right side will have been preserved is discharged to 6, thus be discharged to outside the system; First chamber 301 is realized following function: i.e. the used dialysis solution retrieved from dialyser 8 of first waste liquid in left side zone 304, first dialysis solution zone 303 on right side is sent into the dialysis solution for preparing in the dialyser 8.And in step (2); With above-mentioned steps on the contrary; Second chamber 311 is realized following function, i.e. the used dialysis solution retrieved from dialyser 8 of second waste liquid on right side zone 314, and second dialysis solution zone 313 in left side is sent into the dialysis solution for preparing in the dialyser 8; First chamber 301 is realized following function: i.e. the dialysis solution for preparing of liquid device 11 is transferred in first dialysis solution on right side zone, 303 storages from dialysis solution; The recycling and processing device of stating after the used dialysis solution that first waste liquid zone 304 in left side will have been preserved is discharged to 6, thus be discharged to outside the system.As long as alternately constantly carry out above step (1), step (2) repeatedly; First chamber 301 and second chamber 311 continuous alternate functions just then; The storage of the dialysis solution that promptly prepares continuously, liquor charging, the recovery of used dialysis solution, discharge opeing operation.
For the patient; The dialysis solution for preparing in the assurance inflow dialyser and the balance between revenue and expenditure of the used dialysis solution that flows out dialyser are very important; In the present embodiment; Just because each cyclic process, be sent to dialyser and the amount of the dialysis solution that takes out from dialyser all is certain (being the volume of first chamber 301 or second chamber 311), thereby can strictly guarantee the balance that dialysis solution is supplied with.
In the method for present embodiment, guarantee the second liquor charging valve V7, the second recovery valve V5, the first tapping valve V3 and first storage valve V1 switch simultaneously.Switch when guaranteeing the second storage valve V8, the second tapping valve V6, the first recovery valve V4, the first liquor charging valve V2.In addition, between dialysis solution stowage arrangement 3 and dialyser 8, also be provided with dialysis solution driving device 4, in the introduction of this dialysis solution stowage arrangement 3, for the purpose of making things convenient for, omitted introduction these dialysis solution driving device 4 modules as relay portion.In addition, because the process for preparation and the method for dialysis solution, promptly the process for preparation of the first stock solution A+, the second stock solution B+ water is transferred in the liquid device 11 at dialysis solution and has been carried out detailed introduction, repeats no more here.But what require emphasis a bit is; In dosing pipeline 202, by the dialysis solution that dialysis solution transfers liquid device 11 to prepare, can pass through dialysis solution storage passage 310 and flow in the respective regions of dialysis solution stowage arrangement 3 (in 303 or second dialysis solution zone, first dialysis solution zone 313).In addition, in the foregoing description, be that example describes so that two chambers to be set.When the quantity of chamber is a plurality of (>=2); Can be in a work process; One of them chamber that makes the first chamber group is that dialyser provides the dialysis solution for preparing and reclaims waste liquid; Any chamber of the second chamber group is responsible for the waste liquid that reclaims is discharged, and the dialysis solution for preparing of liquid device 11 is transferred in storage from dialysis solution.Be used to the chamber use that dialyser provides the following function of this chamber conduct of dialysis solution for preparing and the first chamber group that reclaims waste liquid in the last work process and in next work process, make: promptly; The waste liquid that reclaims is discharged, and the dialysis solution for preparing of liquid device 11 is transferred in storage from dialysis solution.Thus; When using a plurality of chamber; As long as the control mode to each chamber meets the following conditions: promptly in two adjacent work process, be used in forward relatively work process that the work process of chamber after leaning on relatively with the first chamber group of dialyser generation fluid exchange is used for and dialysis solution pumping equipment and dialysis solution are transferred liquid device generation fluid exchange.
In addition; When the quantity of chamber is a plurality of (>=2), also can control chamber as follows: promptly, in a work process; Make at least one chamber (for example being 2) in the chamber group of winning the dialysis solution for preparing is provided and reclaim waste liquid for dialyser simultaneously; Meanwhile, make that at least one chamber (for example being 3) in the second chamber group is discharged the waste liquid that reclaims simultaneously, and the dialysis solution for preparing of liquid device 11 is transferred in storage from dialysis solution.That is, the number of the chamber of the participation work in the above-mentioned first chamber group and the second chamber group can be for arbitrarily.As long as the summation (summations of above-mentioned 2 cavity volume) of the dischargeable capacity of the chamber of the participation work process of the satisfied first chamber group equates with the summation (summations of above-mentioned 3 cavity volume) of the dischargeable capacity of the chamber of the participation work process of the second chamber group.
In addition; The flow rate regulating valve of being located on the dialysis solution liquor charging passage 309 322 carries out co-ordination as follows with flow-sensint unit 324; The dialysis solution that promptly monitors in the dialysis solution liquor charging passage 309 when flow-sensint unit 324 flows the time ratio scheduled time in short-term; Then the aperture of the valve of flow rate regulating valve 322 reduces, thereby makes the mobile time of dialysis solution elongated.In like manner, the time ratio scheduled time long time if dialysis solution flows, then the aperture of the valve of flow rate regulating valve 322 increases, thereby the dialysis solution time of flowing is shortened.
In addition; The flow rate regulating valve of being located on the dialysis solution liquor charging passage 309 322 is mainly used in the flow of controlling dialysis solution; But in the practical work process; Often between the entrance and exit of flow rate regulating valve 322, have pressure reduction, the change of this pressure reduction can cause the effect of flow adjustment to be had a greatly reduced quality, even can't make the flow value of the stability of flow of dialysis solution in regulation; For fear of the generation of this situation, between dialysis solution liquor charging passage 309 and waste liquid recovery approach 319, be provided with the constant flow rate valve 323 that is used to regulate the fluid pressure that is applied to flow rate regulating valve 322 two ends usually.Fig. 5 is the operation principle sketch of constant flow rate valve.Here for convenience's sake, only connecting one first chamber 301, and omit dialysis solution driving device 4 and describe for example.
As shown in Figure 5; The constant flow rate valve 323 that present embodiment adopted comprises left shell 331, right shell body 332, movable next door 333 and support 329; Wherein, after left shell 331 assembled with right shell body 332, inside was formed with the liquid containing cavity; Above-mentioned movable next door 333 is arranged in the above-mentioned containing cavity, and under external force can be in containing cavity move left and right.In addition, above-mentioned movable next door 333 also is divided into recovery chamber 334 (being formed by left shell 331 and movable next door 333) and the liquor charging chamber 335 (formed by right shell body 332 and movable next door 333, and inside being provided with spring 330) that does not communicate with above-mentioned containing cavity.In addition, on left shell 331, also be provided with and reclaim waste liquid inlet 336, the waste liquid outlet 337 that chamber 334 liquid communicate.On right shell body 332, also be provided with the dialysis solution inlet 338, the dialysis solution outlet 339 that communicate with liquor charging chamber 335 liquid.Wherein, waste liquid inlet 336, waste liquid outlet 337 are connected with first waste liquid zone 304 of dialyser outlet 8, first chamber 301 respectively; Dialysis solution inlet 338, dialysis solution outlet 339 are connected with first dialysis solution zone 303, dialyser 8 inlets of first chamber 301 respectively.Its flow rate regulating valve 322 is connected between dialysis solution inlet 338 and first dialysis solution zone 303.
Concrete work process is following, if promptly the pressure P 1 of flow rate regulating valve 322 arrival ends is excessive, the pressure P of the port of export 2 hour; Then the pressure in the recovery chamber 334 of constant flow rate valve 323 becomes big; Then promote movable next door 333 to liquor charging chamber 335 1 side shiftings, when pressure is enough big, movable next door 333 butts to dialysis solution outlet 339; That is, constant flow rate valve 323 is closed.At this moment, first next door 302 continues to move to first dialysis solution zone 303 under the thrust of useless dialysis solution; Promptly continuously via flow rate regulating valve 322; For dialysis solution inlet 338 supplies dialysis solution, owing to this moment constant flow rate valve 323 is closed, so; Dialysis solution accumulates between flow rate regulating valve 322 ports of export and the dialysis solution inlet 338, thereby the pressure P 2 of flow rate regulating valve 322 ports of export will become big.In like manner, if the pressure P 1 of flow rate regulating valve 322 arrival ends is too small, when the pressure P 2 of the port of export is big; Then the pressure in the recovery chamber 334 of constant flow rate valve 323 diminishes; Then movable next door 333 is to reclaiming chamber 334 1 side shiftings, and when arriving to a certain degree, dialysis solution outlet 339 is left in movable next door; That is, constant flow rate valve 323 is opened.Situation when closing is compared, and the accumulative phenomenon of dialysis solution do not occur, so the pressure P 2 of flow rate regulating valve 322 ports of export will diminish.So, when fluctuation appears in the pressure differential at flow rate regulating valve 322 two ends, will adjust, increase the reliability of the flow adjustment of flow rate regulating valve 322 greatly through constant flow rate valve 323.
III, dialysis solution driving device 4
As shown in Figure 6, be the system flow chart of the dialysis solution driving device 4 of present embodiment.Dialysis solution driving device 4 comprises: the dialysis solution feeding portion 401 that is connected with an end of dialyser 8; It is used for the dialysis solution for preparing that dialysis solution stowage arrangement 3 is supplied with is supplied to dialyser 8; And the dialysis solution that is connected with the other end of dialyser 8 gives back portion 402, and it is used to make dialyser 8 used dialysis solution to turn back to dialysis solution stowage arrangement 3.
Dialysis solution is given back portion 402 and is comprised interconnected hydraulic pressure detector 403, blood leakage detector 404, driving pump 405, circulating slot 406 successively according to the direction from dialyser 8 to dialysis solution stowage arrangement 3.And dialysis solution is given back portion 402 and is comprised that also the useless dialysis solution that is used for driving pump 405 is discharged resupplies the driving pump circulating line 407 to driving pump 405, and (operating pressure is 0.9kgf/cm also to be provided with overflow valve 408 on this driving pump circulating line 407 2).In addition, dialysis solution is given back portion 402 and is leaned on an end of hydraulic pressure detector 403 to link to each other with dialyser 8, and entering the mouth by an end of circulating slot 406 and waste liquid on the above-mentioned constant flow rate valve 323 336 is connected.Therefore need to prove that in addition dialysis solution driving device 4 is only given back portion 402 at said dialysis solution and had the driving pump 405 as dialysis solution driving device 4 power sources, not only reduced equipment cost and energy consumption, and also miniaturization comparatively of whole driving device structure.
Wherein, whether hydraulic pressure detector 403 to be used to monitor the hydraulic pressure that dialysis solution gives back in the pipeline of portion 402 normal.Blood leakage detector 404 is monitored through the transmittance of the useless dialysis solution in the pipeline of dialysis solution being given back portion 402, thereby judges in the useless dialysis solution whether sneak into blood; Particularly, photoelectrical coupler (figure slightly) is set in stream, when taking place to leak the situation of blood, the light acceptance amount of photoelectrical coupler will reduce, and judges leakage blood with this.In addition, under the contaminated situation of blood leakage detector 404 self, even do not leak blood; The light-receiving amount of optocoupler is reduced and the generation false alarm; For fear of this situation, during trial run before dialysis (when dialyser 8 is not installed), blood leakage detector 404 is detected; Preferably has under the situation that the light-receiving amount reduces the rise blood leakage detector 404 of this function of the output of light-emitting component.In addition; Driving pump 405 not only drives first waste liquid zone 304 (or second waste liquids of second chamber 311 zone 314) that is back to first chamber 301 from the used dialysis solution of dialyser 8 discharges, because first waste liquid zone 304 constantly is supplied to waste liquid as the power source of dialysis solution driving device; Promoting first next door 302 simultaneously moves to first dialysis solution zone 303; Impel the dialysis solution in first dialysis solution zone 303 to discharge, and be supplied to dialyser through dialysis solution liquor charging passage 309, dialysis solution feeding portion 401, thereby; Whole drive part only needs a driving pump 405 can realize the driving process, and driving pump 405 is preferably magnetic suspension pump here.This compared with must use the situation of two pumps in the past, had reduced cost, had also realized miniaturization.And the setting of overflow valve 408 is to be used for making that the outlet side of circulating slot 406 keeps certain pressure, the protecting component when also can be used as pressure anomaly simultaneously.Here, the operating pressure with this overflow valve 408 is made as 0.9kgf/cm 2, the setting pressure 1.1kgf/cm of this and front feeding overflow valve 110 2Compare smaller.Because the temperature of the water in liquid-feeding pump 107 downstreams in the water feeder 1 is approximately (37 ℃～38 ℃); And the temperature of the water in driving pump 405 downstreams is about 35 ℃; Thereby pressure also can correspondingly reduce, and therefore the operating pressure with overflow valve 408 is made as lower 0.9kgf/cm 2
Introduce dialysis solution feeding portion 401 below.Dialysis solution feeding portion 401 comprises the sample port 409 that connects successively according to the direction from dialyser 8 to dialysis solution stowage arrangement 3; The first temperature monitoring parts 410 (temperature detection critesistor) and the second temperature monitoring parts 411 (temperature revisal critesistor); Be used to monitor the concentration monitor parts 412 (concentration monitor electrode) of the concentration of the dialysis solution in the pipeline of dialysis solution feeding portion 401; And be used to make dialysis solution (the first stock solution A+, the second stock solution B+ water) abundant; Mixed uniformly mixing channel 413.Dialysis solution feeding portion 401 leans on an end of the first temperature monitoring parts 410 to be connected with dialyser 8, exports 339 by an end of mixing channel 413 and dialysis solution on the above-mentioned constant flow rate valve 323 and is connected.
In addition, dialysis solution driving device 4 also comprises is located at the other dismountable bypass adapter 414 of dialyser, and the bypass adapter 414 here is used to be communicated with dialysis solution feeding portion 401 and gives back two ends leaning on dialyser one end in the portion 402 with dialysis solution.In the practical operation; Give back leaning on two ends of dialyser 8 one ends in the portion 402 in dialysis solution feeding portion 401 with dialysis solution and be equipped with sample port 409; Thereby, when needs are connected into bypass adapter 414, only need make two sample port 409 of its both ends and this be connected and get final product.Certainly, this bypass adapter 414 can not be connected in the path in normal dialysis procedure, the general preparatory stage before dialysis, or after state wash phase the time just can use.
In addition; Dialysis solution feeding portion 401 above-mentioned is provided with two temperature components: the first temperature monitoring parts 410 (temperature detection critesistor) and the second temperature monitoring parts 411 (temperature revisal critesistor); Be for mutual contrast on the one hand; When a side is broken down, can in time find and safeguard.On the other hand, the first above-mentioned temperature monitoring parts 410 are and and the temperature control critesistor coordination that is provided with in the dialysis solution accent liquid device 11.Particularly; The temperature difference of the monitor temperature control critesistor 105 and the first temperature monitoring parts 410 when this difference is big, can think that the temperature of dialysis solution does not reach the regulation requirement; 104 pairs of water sources of control heater heat, and improve the temperature of dialysis solution with this.
Above-mentioned when dialysis solution stowage arrangement 3 is introduced, will be except that water pump 321, constant flow rate valve 323, flow-sensint unit 324, and flow rate regulating valve 322 incorporates in the scope into dialysis solution stowage arrangement 3.In fact, above-mentioned four elements also can incorporate in the scope into dialysis solution driving device 4 as the parts of flow adjustment.In addition; Mixing channel 413 not only can be arranged between constant flow rate valve 323 and the concentration monitor parts 412; Also can select to be arranged on the dialysis solution liquor charging passage 309 (figure slightly), thereby make that the effusive dialysis solution for preparing can be realized mixing more equably from the dialysis solution zone at once.
Next, in conjunction with above-mentioned dialysis solution stowage arrangement 3, the work process of whole dialysis solution driving device 4 is described (control procedure for constant flow rate valve 323 was introduced in detail, so locate to repeat no more).At first; Make driving pump 405 running as driving force, then from the dialysis solution of dialysis solution stowage arrangement 3 through after the abundant stirring of mixing channel 413, the uniform mixing, get into flow-sensint unit 324 and flow rate regulating valve 322; The flowing time of corresponding dialysis solution is adjusted its flow.Afterwards, carried out further after the adjustment, got into successively after concentration monitor parts 412, the second temperature monitoring parts 411, the first temperature monitoring parts 410 and the sample port 409, entered into the inlet of dialyser 8 through 323 pairs of flows of constant flow rate valve.After the blood that enters into dialysis solution and patient in the dialyser 8 acts on fully, dialyses; From the outlet of dialyser 8 behind sample port 409, hydraulic pressure detector 403, blood leakage detector 404, driving pump 405; Via constant flow rate valve 323, get in the waste liquid zone (second waste liquid zone 314 of first waste liquid zone, 304 or second chamber 311 of first chamber 301) of chamber.Promptly constitute a complete circulation, and the amount of the amount of the dialysis solution for preparing of concrete entering dialyser 8 and the used dialysis solution that returns from dialyser 8 guarantees the balance of revenue and expenditure through dialysis solution stowage arrangement 3.
In addition, in the preparatory stage or when dialysis apparatus cleaned, the end near dialyser that dialysis solution feeding portion 401 and dialysis solution are given back portion 402 is connected to the two ends of bypass adapter 414, plays the effect that makes whole system formation path.
In addition, the structure of this dialysis solution driving device also is not limited thereto, and for example, the order of connection of above-mentioned each element can be any as required also; Hydraulic pressure detector 403 also can be arranged in the dialysis solution feeding portion 401.When thinking that dialysis solution driving device 4 comprises constant flow rate valve 323; Can think that constant flow rate valve 323 is located at dialysis solution feeding portion 401 and dialysis solution is given back between the portion 402, and be used to regulate and be applied to dialysis solution feeding portion 401 and dialysis solution and give back the fluid pressure in the pipeline of portion 402.And comprise in the dialysis solution feeding portion 401 and promptly be not limited to two temperature monitoring parts by the temperature monitoring parts that are used to monitor temperature in the dialysis solution feeding portion pipeline, also can be one, three even a plurality of.
IV, dialysis solution rinser 5
The dialysis solution rinser 5 of present embodiment comprises: at least one cleanout fluid provides portion, and through the cleaning cover that pipeline one end is connected with this cleanout fluid portion of providing, an end is connected with the cleaning end interface of dialysis apparatus, has taken in this cleaning end interface in this cleaning cover.This cleanout fluid portion of providing comprises that cleanout fluid provides container and the valve that provides container to be connected with this cleanout fluid; When this cleanout fluid portion of providing is a plurality of; After each this cleanout fluid provides the valve of portion all to have an end and other cleanout fluid to provide the respective ends of the valve of portion to interconnect, be connected with this filter washing water inlet of this cleaning cover.Lower end or middle part are located in the filter washing water inlet of this cleaning cover.
And cleanout fluid provides the number of portion, the kind of cleanout fluid, the number of cleaning cover not to limit; (by the situation that the is provided with decision of cleaning end interface) can be chosen according to actual needs; Here to choose two kinds of cleanout fluid: medicinal liquid and acid solution; Select two cleaning covers to describe for example, shown in Figure 7 is the system flow chart of dialysis solution rinser 5.As shown in Figure 7, the above-mentioned cleanout fluid portion of providing comprises: first cleanout fluid that is equipped with medicinal liquid provides container 501 and connected valve V20-1, valve V18; Second cleanout fluid that is equipped with acid solution provides container 511 and connected valve V20-2, valve V19; Clean cover and comprise that the first stock solution A cleans cover 502, the second stock solution B and cleans cover 512; Middle part or bottom (figure slightly) of cleaning cover 502 at the first stock solution A also are provided with first filter washing water inlet 503, and middle part or bottom (figure slightly) of cleaning cover 512 at the second stock solution B also are provided with second filter washing water inlet 513.The annexation of above-mentioned each element is following: promptly valve V18 and V19 provide an end of container to interconnect away from cleanout fluid after, be connected with second filter washing water inlet 513 with first filter washing water inlet 503.
Here, clean end interface and transfer the stock solution drawing section that is provided with on the liquid device 11, and each stock solution drawing section has the size that can be complementary with above-mentioned cleaning cover for dialysis solution at dialysis apparatus.The cleanout fluid driver part provides the cleanout fluid in the container to be drawn into the parts that clean end interface via cleaning cover cleanout fluid as being used for, and can adopt dialysis solution to transfer raw liquor pump 201 ' (piston pump 201) in the liquid device 11.Next the situation of introducing the whole dialysis apparatus of dialysis solution rinser 5 cleanings is (because other each several part of dialysis apparatus has all been done detailed introduction and diagram in the above; Thereby, be that example describes only here with the Fig. 7 that has comprised dialysis solution making parts 2 and dialysis solution rinser 5).As shown in Figure 7; In aforementioned introduction about dialysis solution making parts 2; To adopt two kinds of stock solutions: the first stock solution A and the second stock solution B; And be provided with two stock solution drawing sections: the first stock solution A drawing section 212 and the second stock solution B drawing section 222 describe for example, and with the drive source of piston pump 201 as the various stock solutions of absorption.When the dialysis solution rinser 5 of present embodiment is used for cleaning dialysis apparatus; Place first stock solution A cleaning cover, 502, second stock solution B cleaning to overlap in the middle of 512 respectively the first stock solution A drawing section 212 and the second stock solution B drawing section 222; Like this, in the specific operation process, the corresponding valve in the portion is provided as long as open cleanout fluid; Make and piston pump 201 actions just can provide container via cleaning cover, stock solution drawing section, stock solution suction passage entering dosing pipeline 202 from cleanout fluid cleanout fluid.Transfer liquid device 11 as inlet with dialysis solution, utilize the circulation line of former dialysis solution to flow through whole dialysis apparatus inside, to reach better cleaning effect.
In the above embodiments, the structure of dialysis solution rinser 5 is not limited to this, can also be other.For example: the number of cleaning cover is corresponding according to the number of cleaning end interface.And when cleanout fluid provides portion's number to be one, can comprise directly that cleanout fluid provides container, and not necessarily to comprise valve; When the cleanout fluid portion of providing when being a plurality of, each cleanout fluid provide portion valve provide the end of container also can not to be connected away from cleanout fluid, but respectively through separate duct with connecting between the filter washing water inlet of cleaning cover.In addition, cleaning end interface and be not limited to the stock solution drawing section, also can be the joint that is provided with of dosing pipeline etc.And clean end interface and not only can be located at dialysis solution accent liquid device, also can be located at other part of dialysis apparatus, for example position such as dialysis solution stowage arrangement 3, dialysis solution driving device 4.Simultaneously; Present embodiment is to transfer raw liquor pump 201 in the liquid device 11 ' as (promptly the transferring the raw liquor pump 201 of the absorption dialysis solution stock solution of liquid device 11 ' as the cleanout fluid driver part of this dialysis solution rinser 5 with dialysis solution) of the drive source of dialysis solution rinser 5 with dialysis solution; In the process of practical operation; Also can be so that be provided with independently drive source (for example driving pump of piston pump or other kind etc.) in the dialysis solution rinser 5; Can increase its versatility greatly like this, be not limited in specific dialysis apparatus and use, even can be as the device for cleaning of non-dialysis device.In addition; Can also at the ad-hoc location of dialysis solution rinser 5 filter be set according to the needs of reality; For example, can be respectively provide between the container 501, provide between the container 511 and at valve V18 with clean between the filter washing water inlet of cover and connect filter at valve V20-2 and second cleanout fluid at valve V20-1 and first cleanout fluid.
In addition; As shown in Figure 7, valve V20-1 is made as the valve that can open three directions (first direction, second direction, third direction) simultaneously, the first direction port is connected with valve V 18; Make the second direction port and first cleanout fluid provide container 501 to be connected; And, when above-mentioned both direction conducting, be called first conducting state of valve V20-1.Make the third direction port of valve V20-1 be communicated with Drainage pipe 506, and when first direction and the conducting of third direction port, be called second conducting state of valve V20-1 through check valve 504.In like manner valve V20-2 is made as the valve that can open three directions (four directions is to, the 5th direction, the 6th direction) simultaneously; The four directions is connected with valve V19 to port; Make the 5th direction port and second cleanout fluid provide container 511 to be connected; And, when above-mentioned both direction conducting, be called first conducting state of valve V20-2.The 6th direction port that makes valve V20-2 is communicated with Drainage pipes 507 through check valve 505, and when the four directions to the 6th direction port conducting the time, be called second conducting state of valve V20-2.
What also need specify is; When 5 pairs of whole dialysis apparatuss of dialysis solution rinser clean; Being located at dialysis solution transfers the liquid-feeding pump 107 of liquid device 11 that the water pressurization of outside supply, the water that also will pressurize and the mixed liquor of cleanout fluid are delivered to dialysis solution stowage arrangement 3; And the driving pump 405 of being located at dialysis solution driving device 4 will be delivered to dialysis solution driving device 4 inside by the water of dialysis solution stowage arrangement 3 supplies and the mixed liquor of cleanout fluid, thereby at the inner liquid flow path that forms of whole dialysis apparatus.
In addition, because the dialysis apparatus of present embodiment has adopted above-mentioned dialysis solution rinser 5, therefore the above-mentioned all embodiments about dialysis solution rinser 5 comprise that various distortion also all are applicable to this dialysis apparatus.
Below, the concrete cleaning method of dialysis apparatus is described.
That is, the dialysis solution cleaning method of present embodiment may further comprise the steps:
(1), the preparatory stage: replace dialyser and is connected with the bypass adapter, each stock solution drawing section is put into to clean overlap with dialysis solution driving device 4.
Particularly; Under the state of closing each valve V10, V11, V12, V26, V18, V20-1, V19, V20-2; The first stock solution A drawing section 212 and the second stock solution B drawing section 222 are taken out from the first stock solution A container 210 and the second stock solution B container 220 respectively, and be positioned over respectively within first stock solution A cleaning cover, the 502 and second stock solution B cleaning cover 512.Owing in the cleaning process, the first stock solution A drawing section, 212 integral body are soaked in the middle of the cleanout fluid of first stock solution A cleaning cover, 502 inside, thereby can guarantee that the internal-external of the first stock solution A drawing section 212 all is cleaned, thereby reach good cleaning effect.And the situation of the second stock solution B drawing section 222 is also similar, repeats no more here.
(2) provide container 501 to be drawn in the dialysis apparatus from first cleanout fluid first cleanout fluid (the following medicinal liquid of also claiming).
Particularly; Open valve V11, V18, V20-1 (being in first conducting state); Shut off valve V10, V12, V26, V19, V20-2; The piston of piston pump 201 is pulled ormal weight downwards; Then first cleanout fluid provides medicinal liquid in the container 501 through being drawn to dialysis apparatus like lower channel: after promptly passing through filter, valve V20-1, valve V18, filter successively, first filter washing water inlet 503 of cleaning cover 502 middle parts through the first stock solution A gets into the first stock solution A and cleans and overlap 502, after 212 inside and outsides, the first stock solution A drawing section are fully cleaned; Again through the first stock solution A filter 213, valve V11, get into the dosing pipeline 202 of dialysis apparatus, under the combined effect of liquid-feeding pump 107 and driving pump 405 at whole dialysis apparatus internal recycle.If (that perhaps open in this step is valve V12; V18, V20-1 (being in first conducting state); Then medicinal liquid is after passing through filter, valve V20-1, valve V18, filter successively; Second filter washing water inlet 513 of cleaning cover 512 middle parts through the second stock solution B gets into second stock solution B cleaning cover, 512 inside; After 222 inside and outsides, the second stock solution B drawing section are fully cleaned, again through the second stock solution B filter 223, valve V12, get into the dosing pipeline 202 of dialysis apparatus, under the combined effect of liquid-feeding pump 107 and driving pump 405 at whole dialysis apparatus internal recycle.) like this; Can make first cleanout fluid provide the medicinal liquid in the container 501 to flow through the first stock solution A suction passage 211 (or second stock solution B suction passage 221) and get into dialysis apparatus, also can clean the first stock solution A suction passage 211 (or second stock solution B suction passage 221).
(3) make the current in the dialysis apparatus logical, dilute liquid medicine, and the medicinal liquid after the dilution is cleaned the inside of whole dialysis apparatus.
Particularly, only open valve V10, V26, shut off valve V11, V12, V18, V20-1, V19, V20-2 make above-mentioned liquid-feeding pump 107 move, thereby make water in the dialysis apparatus inner loop.In this process, the piston of piston pump 201 moves upward and turns back to the position of regulation, thereby is that follow-up work process is got ready.
(4) make the water in the dialysis apparatus continue circulation, dialysis apparatus inside is cleaned.When soon finishing, the piston of piston pump 201 is pulled the position of regulation downwards, make the pump chamber on top of piston pump 201 be full of water.
(5) make medicinal liquid between piston pump 201 and the valve V20-1 return first cleanout fluid container 501 is provided.
Particularly; Open valve V11, V18, V20-1 (first conducting state); Shut off valve V10, V12, V26, V19, V20-2; And the piston that makes piston pump 201 ormal weight (volume of the ducted medicinal liquid between the volume of the water that this amount of moving upward is discharged and piston pump 201 and the valve V20-1 equates) that moves upward; Provide in the container 501 thereby the medicinal liquid between piston pump 201 and the valve V20-1 is pushed back first cleanout fluid, can prevent the dialysis solution of liquid medicine contamination in the follow-up dialysis apparatus operation process like this.
(6) will replace fully at the pipeline space water between piston pump 201 and the valve V20-1.Particularly; Make valve V11, V18 continue to keep opening state; Make valve V20-1 be in second conducting state, shut off valve V10, V12, V26, V19, V20-2, and make the piston of piston pump 201 move upward required amount (with this water of being discharged of moving upward can be fully with the flushing of pipeline between piston pump 201 and the valve V20-1 totally for good); Thereby water is via first direction and the third direction of valve V20-1; Get into Drainage pipe 506 via check valve 504, that is, and with the complete water displacement of the pipeline between piston pump 201 and the valve V20-1; Can fully clean residual medicinal liquid in the pipeline or among the valve V20-1 like this, also can prevent the dialysis solution stock solution of liquid medicine contamination in the follow-up dialysis apparatus operation process.
So far, accomplished with the cleaning of medicinal liquid whole dialysis apparatus.Next the process of dialysis apparatus being cleaned with acid solution will be described.This process and said process are similar:
(7) provide container 511 to be drawn in the dialysis apparatus from second cleanout fluid second cleanout fluid (the following acid solution of also claiming).
Particularly; Open valve V12, V19, V20-2 (being in first conducting state); Shut off valve V10, V11, V26, V18, V20-1; The piston of piston pump 201 is pulled ormal weight downwards; Then second cleanout fluid provides acid solution in the container 511 through being drawn to dialysis apparatus like lower channel: after promptly passing through filter, valve V20-2, valve V19, filter successively, second filter washing water inlet 513 of cleaning cover 512 middle parts through the second stock solution B gets into the second stock solution B and cleans and overlap 512 inside, after 222 inside and outsides, the second stock solution B drawing section are fully cleaned; Again through the second stock solution B filter 223, valve V12, get into the dosing pipeline 202 of dialysis apparatus, under the combined effect of liquid-feeding pump 107 and driving pump 405 at whole dialysis apparatus internal recycle.If (perhaps in this step; Open valve V11, V19, V20-2 (being in first conducting state); Acid solution is after passing through filter, valve V20-2, valve V19, filter successively so; Will clean first filter washing water inlet, 503 entering, the first stock solution A cleaning cover 502 at cover 502 middle parts through the first stock solution A; After 212 inside and outsides, the first stock solution A drawing section are fully cleaned, again through the first stock solution A filter 213, valve V11, get into the dosing pipeline 202 of dialysis apparatus, under the combined effect of liquid-feeding pump 107 and driving pump 405 at whole dialysis apparatus internal recycle.) like this; Can make second cleanout fluid provide the acid solution in the container 511 to flow through the second stock solution B suction passage 221 (or first stock solution A suction passage 211) and get into dialysis apparatus, can realize cleaning the second stock solution B suction passage 221 (or first stock solution A suction passage 211).
(8) make the current in the dialysis apparatus logical, the dilution acid solution, and the acid solution after the dilution is cleaned the inside of whole dialysis apparatus.
Particularly, only open valve V10 and V26, shut off valve V11, V12, V18, V20-1, V19, V20-2 make above-mentioned liquid-feeding pump 107 move, thereby make water in the dialysis apparatus inner loop.In this process, the piston of piston pump 201 moves upward and turns back to the position of regulation, thereby is that follow-up work process is got ready.
(9) make the water in the dialysis apparatus continue circulation, dialysis apparatus inside is cleaned.When soon finishing, the piston of piston pump 201 is pulled the position of regulation downwards, make the pump chamber on top of piston pump 201 be full of water.
(10) make acid solution between piston pump 201 and the valve V20-2 return second cleanout fluid container 511 is provided.
Particularly; Open valve V12, V19, V20-2 (first conducting state); Shut off valve V10, V11, V26, V18, V20-1; And with the piston of piston pump 201 ormal weight (volume of the ducted acid solution between the volume of this water of being discharged of moving upward and piston pump 201 and the valve V20-2 equates) that moves upward; Provide in the container 511 thereby the acid solution between piston pump 201 and the valve V20-2 is pushed back second cleanout fluid, can prevent that like this acid solution from polluteing the dialysis solution in the follow-up dialysis apparatus operation process.
(11) will replace fully at the pipeline space water between piston pump 201 and the valve V20-2.Particularly; Make valve V12, V19 continue to keep opening state; Make valve V20-2 be in second conducting state, shut off valve V10, V11, V26, V18, V20-1, and make the piston of piston pump 201 move upward required amount (with this water of being discharged of moving upward can be fully with the flushing of pipeline between piston pump 201 and the valve V20-2 totally for good); Thereby water via the four directions of valve V20-2 to the 6th direction; Get into Drainage pipe 507 via check valve 505, that is, and with the complete water displacement of the pipeline between piston pump 201 and the valve V20-2; Can fully clean residual acid solution in the pipeline or among the valve V20-2 like this, can prevent that also acid solution from polluteing the dialysis solution stock solution in the follow-up dialysis apparatus operation process.
Temperature (for example preferred more than 90 ℃) when (12) using aforesaid heater 104 that water is heated to above common dialysis at last comes whole dialysis apparatus inside is cleaned.Particularly; Shut off valve V11 and V12; Make hot water get into the dialysis solution retracting device 6 that dialysis solution is transferred liquid device 11, dialysis solution stowage arrangement 3, dialysis solution driving device 4 (forming path through bypass adapter 414), stated after getting into successively, thereby reach the purpose of cleaning whole dialysis apparatus system.
Certainly, the application still carries out the cleaning of acid solution branch road earlier about the cleaning of carrying out the medicinal liquid branch road earlier, and its order also can freely be selected according to the situation of reality.
V, dialysis solution discharger 6
Be illustrated in figure 8 as the total system flow chart of dialysis apparatus.
Dialysis solution discharge portion 6 is used for used dialysis solution is discharged to outside the system.As shown in Figure 8, the dialysis solution discharge portion 6 of present embodiment has the Drainage pipe 601 that links to each other with the waste liquid apocenosis passage of dialysis solution stowage arrangement 3, and this Drainage pipe 601 is through aforementioned heat exchanger 103, as the heat exchange source of the cold water that enters into water feeder 1.
Next, with reference to Fig. 8, the work process of whole dialysis apparatus is described.
A, at first be the preparatory stage, bypass adapter 414 be connected to dialysis solution feeding portion 401 give back leaning on two ends of dialyser 8 one ends in the portion 402, whole system is formed a fluid path with dialysis solution.
B, start the water supply part 1 that dialysis solution is transferred liquid device 11 then, make in the fluid path of whole system to be full of water, remove the air in the pipeline as much as possible.
Particularly, supply with from the outside through purifying or after comparatively the water of cleaning gets into first pipeline 111, through giving after liquid filter 101 carries out purification filtering, impurity or foreign body are removed; Get into air relief valve 102 it is reduced pressure, carry out preheating by heat exchanger 103 again, reach after certain temperature through post-decompression water; Get into heater 104 and carry out further heat temperature raising, after this, make dissolved air expansion in the water via choke manifold 106; Assembling becomes bigger bubble; Again through after liquid-feeding pump 107 pressurizes, make that in deaerating tank 108 gas that contains in the water is emitted, promptly obtain having water set point of temperature, comparatively clean.This moisture is two-way, and one the road flows into circulating line 109, again behind feeding overflow valve 110, converges with water from heat exchanger 103, by heater 104 heating, has formed a partial cyclic process here to satisfy the water demand in the system at any time once more; Other one tunnel dosing pipeline 202 through dialysis solution producing device 2 gets into dialysis solution stowage arrangement 3, then through dialysis solution driving device 4, turns back to dialysis solution stowage arrangement 3 again, the dialysis solution discharger 6 discharge systems that warp is connected with dialysis solution stowage arrangement 3.
This stage can take down bypass adapter 414 after accomplishing, and dialysis solution feeding portion 401 is connected with the entrance and exit of dialyser respectively with two ends leaning on dialyser one end that dialysis solution is given back in the portion 402.Prepare the beginning dialysis procedure.
C, transfer the dialysis solution of liquid device 11 to make parts 2 preparation dialysis solution by dialysis solution.
Particularly, water uniform temperature, clean was arranged after inflow-rate of water turbine adjustment choke manifold 209 is carried out the flow adjustment, entered in the piston pump 201 through valve V10 through what water supply part 1 was handled.The method of concrete preparation dialysis solution comprises the steps:
(1) with this first dosing pipeline 205, the second dosing pipeline 206, the 3rd dosing pipeline 207 fills with water all, just make whole dosing pipeline 202 be full of water.
(2) the first stock solution A and the second stock solution B with ormal weight is drawn into respectively in the first dosing pipeline 205 and in the second dosing pipeline 206.
(3) afterwards through above-mentioned steps (2); The first stock solution A and the second stock solution B are drawn into respectively in the first dosing pipeline 205 and the second dosing pipeline 206; And diluted to a certain extent by the water that had originally in the dosing pipeline 202; Proceed last step then: this first dosing pipeline 205, the second dosing pipeline 206, the 3rd dosing pipeline 207 are supplied with water, the second stock solution B and the water drawn in the first stock solution A that drawn in the liquid distribution pipe road 205 of winning, the second dosing pipeline 206 are supplied in the dialysis solution stowage arrangement 3.
D, coordinate dialysis solution by dialysis solution stowage arrangement 3 and transfer liquid devices 11, dialysis solution driving device 4,6 pairs of dialysis solution that prepare of dialysis solution discharger and used dialysis solution to allocate.
Particularly, the aforesaid operations process may further comprise the steps:
(1) makes first waste liquid zone 304 of first chamber 301 reclaim used dialysis solution, make first dialysis solution zone, the 303 interior dialysis solution that prepare of first chamber 301 deliver to dialyser 8; Make second dialysis solution zone 313 of second chamber 311 preserve the dialysis solution for preparing, second waste liquid zone, the 314 interior used dialysis solution of second chamber 311 are discharged.
Particularly; In the above-mentioned steps (1); Start and be located at the driving pump 405 on the dialysis solution driving device 4; When making system be in normal operation, open the second storage valve V8 that is located on second dialysis solution storage passage 316, be located at the second tapping valve V6 on the second waste liquid apocenosis passage 318, be located at the first recovery valve V4 on the first waste liquid recovery approach 307, be located at the first liquor charging valve V2 on the first dialysis solution liquor charging passage 305, and close other four valves as drive source.Then first chamber 301 and 311 co-operatings of second chamber.
The work process of first chamber 301 is described first.Promptly from the used dialysis solution of dialyser 8 from the outlet of dialyser 8 behind sample port 409, hydraulic pressure detector 403, blood leakage detector 404, driving pump 405, enter into first waste liquid zone 304 of first chamber 301 via constant flow rate valve 323, the first waste liquid recovery approach 307; In this process, side by side oppress first next door 302, to first dialysis solution zone, 303 1 side shiftings; Make in the middle of first dialysis solution zone 303, in last cycle of operation dialysis solution that preserved, that prepare; Get into mixing channel 413 via the first dialysis solution liquor charging passage 305, after the abundant stirring of process mixing channel 413, the uniform mixing, get into flow-sensint unit 324 and flow rate regulating valve 322; The flowing time of corresponding dialysis solution is adjusted its flow.Afterwards, carried out further after the adjustment, got into successively after concentration monitor parts 412, the second temperature monitoring parts 411, the first temperature monitoring parts 410 and the sample port 409, entered into the inlet of dialyser 8 through 323 pairs of flows of constant flow rate valve.
Meanwhile, second chamber 311 carries out following work process: promptly transfer the dialysis solution for preparing of the dosing pipeline 202 of liquid device 11 from above-mentioned dialysis solution, get into via second dialysis solution storage passage 316 in second dialysis solution zone 313 of second chamber 311; In this process; Side by side oppress second next door 312 to second waste liquid zone, 314 1 side shiftings; Make second waste liquid zone, 314 interior, in last cycle of operation, preserved, the used dialysis solution of second chamber 311, be discharged to via the second waste liquid apocenosis passage 318 in the Drainage pipe 601 of dialysis solution discharger 6.
(2) make second waste liquid zone 314 of second chamber 311 reclaim used dialysis solution, make second dialysis solution zone, the 313 interior dialysis solution that prepare of second chamber 311 deliver to dialyser 8; Make first dialysis solution zone 303 of first chamber 301 preserve the dialysis solution for preparing, first waste liquid zone, the 304 interior used dialysis solution of first chamber 301 are discharged.
In the above-mentioned steps (2); Open the second liquor charging valve V7 that is located on the second dialysis solution liquor charging passage 315, be located at the second recovery valve V5 on the second waste liquid recovery approach 317, be located at the first tapping valve V3 on the first waste liquid apocenosis passage 308, be located at the first storage valve V1 on first dialysis solution storage passage 306; And close other four valves, then first chamber 301 and 311 co-operatings of second chamber.
The work process of second chamber 311 is described first.Promptly from the used dialysis solution of dialyser 8 from the outlet of dialyser 8 behind sample port 409, hydraulic pressure detector 403, blood leakage detector 404, driving pump 405, enter into second waste liquid zone 314 of second chamber 311 via constant flow rate valve 323, the second waste liquid recovery approach 317; In this process; Side by side oppress second next door 312 to second dialysis solution zone, 313 1 side shiftings, make in second dialysis solution zone 313, in last step dialysis solution that preserved, that prepare, get into mixing channels 413 via the second dialysis solution liquor charging passage 315; After the abundant stirring of process mixing channel 413, the uniform mixing; Get into flow-sensint unit 324 and flow rate regulating valve 322, the flowing time of corresponding dialysis solution is adjusted its flow.Afterwards, carried out further after the adjustment, got into successively after concentration monitor parts 412, the second temperature monitoring parts 411, the first temperature monitoring parts 410 and the sample port 409, entered into the inlet of dialyser 8 through 323 pairs of flows of constant flow rate valve.
Meanwhile, first chamber 301 carries out following work process: promptly transfer the dialysis solution for preparing of the dosing pipeline 202 of liquid device 11 from above-mentioned dialysis solution, get into via first dialysis solution storage passage 306 in first dialysis solution zone 303 of first chamber 301; In this process; Side by side oppress first next door 302 to first waste liquid zone, 304 1 side shiftings; Make first waste liquid zone, 304 interior, in last step, preserved, the used dialysis solution of first chamber 301, be discharged to via the first waste liquid apocenosis passage 308 in the Drainage pipe 601 of dialysis solution discharger 6.
In above-mentioned adaptation step, guarantee the second liquor charging valve V7, the second recovery valve V5, the first tapping valve V3 and first storage valve V1 switch simultaneously.Switch when guaranteeing the second storage valve V8, the second tapping valve V6, the first recovery valve V4, the first liquor charging valve V2.Like this in the process of whole dialysis treatment, above-mentioned two steps that hocket repeatedly, thus carry out the allotment of dialysis solution continuously.As long as repeat constantly to carry out above step (1), step (2); First chamber 301 and second chamber 311 alternate functions constantly just then; The storage of the dialysis solution that promptly prepares continuously, liquor charging, the recovery of used dialysis solution, discharge opeing operation.
In sum; Only need dialysis solution to transfer liquid device 11 to prepare continuously and have certain density dialysis solution; And offer dialysis solution stowage arrangement 3; Dialysis solution stowage arrangement 3 is coordinated dialysis solution and is transferred liquid devices 11, dialysis solution discharger 6, dialysis solution driving device 4 common actions, can strictly guarantee to get into the dialysis solution for preparing of dialyser and the balance between revenue and expenditure of the useless dialysis liquid measure from dialyser, returned.Certainly, when needed, also can start be located at (between driving pump outlet 405 and the Drainage pipe 601) between waste liquid apocenosis passage 320 and the waste liquid recovery approach 319 remove water pump 321, should work as the moisture of getting rid of as urine to be used to remove in the human body.
And dialysis solution rinser 5 is used for after dialysis treatment carries out preceding or carries out, and whole dialysis apparatus inside is cleaned.Concrete cleaning process can be with reference to the description of IV part in this description.

Claims (11)

1. dialysis solution rinser; Comprise that at least one cleanout fluid provides portion; It is characterized in that; Also comprise and clean cover, said cleaning cover comprises and is used for the filter washing water inlet that is connected with the said cleanout fluid portion of providing, and can be connected with the cleaning end interface of this dialysis apparatus with the mode of the cleaning end interface of taking in dialysis apparatus.
2. dialysis solution rinser according to claim 1; It is characterized in that: the said cleanout fluid portion of providing comprises that cleanout fluid provides container and the valve that provides container to be connected with this cleanout fluid; The said cleanout fluid portion of providing is a plurality of; After each said cleanout fluid provides the valve of portion all to have an end and other cleanout fluid to provide this end of the valve of portion to interconnect, be connected with the said filter washing water inlet of said cleaning cover.
3. dialysis solution rinser according to claim 2; It is characterized in that: said cleanout fluid provides container to comprise to be equipped with first cleanout fluid of medicinal liquid that container (501) is provided and second cleanout fluid that is equipped with acid solution provides container (511), and said cleaning cover comprises that the first stock solution A cleans cover (502) and cleans with the second stock solution B and overlap (512).
4. dialysis solution rinser according to claim 1 is characterized in that: the lower end or the middle part of said cleaning cover is located in the filter washing water inlet of said cleaning cover.
5. according to each described dialysis solution rinser of claim 1～4, it is characterized in that: also comprise being used for providing the cleanout fluid in the container to suck the cleanout fluid driver part that cleans end interface cleanout fluid via cleaning cover.
6. dialysis solution rinser according to claim 5 is characterized in that: said driver part is piston pump (201).
7. dialysis apparatus; It is characterized in that; Comprise the dialysis solution accent liquid device (11), dialysis solution stowage arrangement (3) and the dialysis solution driving device (4) that connect successively; This dialysis solution driving device (4) offers dialyser (8) with the dialysis solution in the dialysis solution stowage arrangement (3), and the used dialysis solution of dialyser (8) is turned back to dialysis solution stowage arrangement (3), and said dialysis apparatus also comprises like each described dialysis solution rinser (5) of claim 1～4.
8. dialysis apparatus according to claim 7 is characterized in that: the cleaning end interface of said dialysis apparatus is dialysis solution and transfers the stock solution drawing section that is used to draw stock solution on the liquid device (11).
9. dialysis apparatus; It is characterized in that: comprise the dialysis solution accent liquid device (11), dialysis solution stowage arrangement (3) and the dialysis solution driving device (4) that connect successively; This dialysis solution driving device (4) offers dialyser (8) with the dialysis solution in the dialysis solution stowage arrangement (3); And the used dialysis solution of dialyser (8) turned back to dialysis solution stowage arrangement (3); Said dialysis apparatus also comprises dialysis solution rinser as claimed in claim 5 (5), and utilizes the raw liquor pump of absorption dialysis solution stock solution that said dialysis solution transfers liquid device (11) as the cleanout fluid driver part of said dialysis solution rinser (5).
10. dialysis apparatus according to claim 9 is characterized in that: said cleanout fluid driver part is the piston pump (201) that is used to draw stock solution.
11. according to each described dialysis apparatus in the claim 7～10; It is characterized in that; Said dialysis solution transfers liquid device (11) also to comprise: the water pressurization that the outside is supplied with is also delivered to the liquid-feeding pump (107) of dialysis solution stowage arrangement (3) with the mixed liquor of the water of pressurization and cleanout fluid, and said dialysis solution driving device (4) comprises delivers to the interior driving pump (405) of dialysis solution driving device (4) with the mixed liquor of water of being supplied with by dialysis solution stowage arrangement (3) and cleanout fluid.
CN2011205555094U 2011-12-27 2011-12-27 Dialyzate cleaning device and dialysis device with same Expired - Fee Related CN202505854U (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103977467A (en) * 2014-04-29 2014-08-13 昆山韦睿医疗科技有限公司 Dialysate temperature monitoring method and device and peritoneum dialyzator
CN105107040A (en) * 2015-09-11 2015-12-02 重庆市澳凯龙医疗器械研究有限公司 Blood purification device with high safety performance
CN109381761A (en) * 2018-11-13 2019-02-26 重庆本善医疗设备有限公司 The device and method for generating peritoneal dialysis liquid is diluted with concentrate

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103977467A (en) * 2014-04-29 2014-08-13 昆山韦睿医疗科技有限公司 Dialysate temperature monitoring method and device and peritoneum dialyzator
CN103977467B (en) * 2014-04-29 2016-06-01 昆山韦睿医疗科技有限公司 A kind of dialysate temperature monitoring method, device and peritoneal dialysis instrument
CN105107040A (en) * 2015-09-11 2015-12-02 重庆市澳凯龙医疗器械研究有限公司 Blood purification device with high safety performance
CN109381761A (en) * 2018-11-13 2019-02-26 重庆本善医疗设备有限公司 The device and method for generating peritoneal dialysis liquid is diluted with concentrate

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