CN202288527U - Fixing device used for preparing mouse femoral bone impairment model - Google Patents
Fixing device used for preparing mouse femoral bone impairment model Download PDFInfo
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- CN202288527U CN202288527U CN2011203740461U CN201120374046U CN202288527U CN 202288527 U CN202288527 U CN 202288527U CN 2011203740461 U CN2011203740461 U CN 2011203740461U CN 201120374046 U CN201120374046 U CN 201120374046U CN 202288527 U CN202288527 U CN 202288527U
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- steel plate
- fixing device
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Abstract
The utility model provides a fixing device used for preparing a mouse femoral bone impairment model, which relates to the field of zoology and comprises a steel plate (1) with five holes, and two stainless steel wires. The two ends of one stainless steel wire A (7) pass through a hole D (5) and a hole E (6) on the steel plate (1) respectively and then are connected together in a knotting manner. The two ends of the other stainless steel wire B (8) pass through a hole A (2) and a hole B (3) on the steel plate (1) respectively and then are connected together in a knotting manner. The fixing device used for preparing a mouse femoral bone impairment model is simple and compact in structure and convenient to manufacture, which can satisfy experimental requirements.
Description
Technical field
This utility model relates to the experimental zoology field, especially a kind of fixture that is used to prepare the damaged model of mouse femur bone.
Background technology
Tissue engineered bone is a developed recently bone transplanting rapidly product, and its osteogenic activity is high, approaches the goldstandard " from the body bone " that bone is transplanted.But the skeletonization mechanism of tissue engineered bone is still not clear, and the osteogenic activity of the tissue engineered bone that different stent materials and seed cell make up needs to detect, and these all need suitable animal model.Mostly existing bone transplantation model is larger animal, as: monkey, sheep, Canis familiaris L., pig etc., advantage is a larger animal, the skeletonization microenvironment approaches the mankind, is applicable to observe graft skeletonization effect; Shortcoming is that expense is high, operation inconvenience, and the strain of specific uses such as shortage transgenic is unfavorable for mechanism researchs such as application organizes engineering bone skeletonization mechanism.Mice is the animal model of human extensive use, and it is with low cost, and the transgenic testing line version of having set up is various, can observe the mechanism of action of range gene in osteogenetic process well.But, be applied to the mouse model of skeletonization research at present, adopt dystopy skeletonization mode more, promptly carry out skeletonization research subcutaneous the grade in non-bone tissue's environment, this can't fine simulation skeletonization microenvironment.The mice osseous tissue is because too tiny, and it is big to carry out original position skeletonization transplantation experiments difficulty, lacks good fixed apparatus and method at present.
Summary of the invention
The purpose of this utility model provides a kind of simple in structure; Anatomical parameters according to tubular bone " femur " maximum in the mice body; The fixture of design is set up the damaged model of bone of the different defect length in mouse femur stage casing, is used to observe graft skeletonization Mechanism Study.
The technical scheme that purpose adopts of this utility model is; Include the steel plate in 5 holes, two stainless steel silks; Tiing a knot behind the hole D that steel plate is passed at its described stainless steel silk A two ends respectively and the hole E is connected, and tiing a knot behind the hole A that another root stainless steel silk B passes at two ends steel plate respectively and the hole B is connected.
When using this utility model; Steel plate is placed on the distal femoral surface; Electric drill is holed on the corresponding osseous tissue of hole A, hole B, hole D, hole E, and stainless steel silk B passes respectively at two ends to tie a knot behind hole A and the hole B and is connected, and stainless steel silk A passes respectively at two ends to tie a knot behind hole D and the hole E and is connected.Steel plate is fixed on the femur, between hole B and hole D, causes femur defect, be fixed on the steel plate, prevent sliding transfer through hole C graft.Because the mice osseous tissue very carefully is difficult to prepare satisfactory lock screw; So fixing relatively firmly with the steel wire bundle that is parallel to the osseous tissue major axis, walk crosswise around the destruction and the slip of steel wire on osseous tissue that can reduce the blood fortune of destroying periosteum and bringing effectively.
The utlity model has simple and compact for structurely, easy to make, can satisfy characteristics such as test requirements document.
Description of drawings
Further specify this utility model below in conjunction with accompanying drawing.
Fig. 1 is that this utility model is bundled in the femur structure sketch map.
Among the figure: D 6-hole, C 5-hole, B 4-hole, A 3-hole, 1-steel plate 2-hole E 7-stainless steel silk A 8-stainless steel silk B 9-has damaged femur 10-graft.
The specific embodiment
As shown in Figure 1; Steel plate 1 places on the damaged femur 9; Electric drill in the hole A2, hole B3, hole D5, hole E6 corresponding damaged femur 9 borings that have are arranged; Stainless steel silk A7 passes respectively at two ends to tie a knot behind hole E6 and the hole D5 and is connected, and stainless steel silk B8 passes respectively at two ends to tie a knot behind hole A2 and the hole B3 and is connected, and injects graft 10 through hole C4.
Claims (1)
1. fixture that is used to prepare the damaged model of mouse femur bone; Include the steel plate (1) in 5 holes, two stainless steel silks; It is characterized in that the hole D (5) that passes steel plate (1) respectively in described stainless steel silk A (7) two ends is connected with the knotting of hole E (6) back, the hole A (2) that another root stainless steel silk B (8) passes at two ends steel plate (1) respectively afterwards ties a knot with hole B (3) and is connected.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2011203740461U CN202288527U (en) | 2011-09-30 | 2011-09-30 | Fixing device used for preparing mouse femoral bone impairment model |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2011203740461U CN202288527U (en) | 2011-09-30 | 2011-09-30 | Fixing device used for preparing mouse femoral bone impairment model |
Publications (1)
Publication Number | Publication Date |
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CN202288527U true CN202288527U (en) | 2012-07-04 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN2011203740461U Expired - Fee Related CN202288527U (en) | 2011-09-30 | 2011-09-30 | Fixing device used for preparing mouse femoral bone impairment model |
Country Status (1)
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CN (1) | CN202288527U (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105640636A (en) * | 2016-02-16 | 2016-06-08 | 西安市红会医院 | Method for adopting loop steel plate for treating ulna coracoid process fractures |
CN110893127A (en) * | 2019-10-15 | 2020-03-20 | 杭州华迈医疗器械有限公司 | Animal thighbone surgery positioning fixing device |
-
2011
- 2011-09-30 CN CN2011203740461U patent/CN202288527U/en not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105640636A (en) * | 2016-02-16 | 2016-06-08 | 西安市红会医院 | Method for adopting loop steel plate for treating ulna coracoid process fractures |
CN110893127A (en) * | 2019-10-15 | 2020-03-20 | 杭州华迈医疗器械有限公司 | Animal thighbone surgery positioning fixing device |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120704 Termination date: 20160930 |