CN202288527U - Fixing device used for preparing mouse femoral bone impairment model - Google Patents

Fixing device used for preparing mouse femoral bone impairment model Download PDF

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Publication number
CN202288527U
CN202288527U CN2011203740461U CN201120374046U CN202288527U CN 202288527 U CN202288527 U CN 202288527U CN 2011203740461 U CN2011203740461 U CN 2011203740461U CN 201120374046 U CN201120374046 U CN 201120374046U CN 202288527 U CN202288527 U CN 202288527U
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CN
China
Prior art keywords
hole
model
stainless steel
steel plate
fixing device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2011203740461U
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Chinese (zh)
Inventor
侯天勇
靳慧勇
李志强
邢军超
易绍萱
许建中
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Third Military Medical University TMMU
First Affiliated Hospital of TMMU
Original Assignee
First Affiliated Hospital of TMMU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by First Affiliated Hospital of TMMU filed Critical First Affiliated Hospital of TMMU
Priority to CN2011203740461U priority Critical patent/CN202288527U/en
Application granted granted Critical
Publication of CN202288527U publication Critical patent/CN202288527U/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

The utility model provides a fixing device used for preparing a mouse femoral bone impairment model, which relates to the field of zoology and comprises a steel plate (1) with five holes, and two stainless steel wires. The two ends of one stainless steel wire A (7) pass through a hole D (5) and a hole E (6) on the steel plate (1) respectively and then are connected together in a knotting manner. The two ends of the other stainless steel wire B (8) pass through a hole A (2) and a hole B (3) on the steel plate (1) respectively and then are connected together in a knotting manner. The fixing device used for preparing a mouse femoral bone impairment model is simple and compact in structure and convenient to manufacture, which can satisfy experimental requirements.

Description

Be used to prepare the fixture of the damaged model of mouse femur bone
Technical field
This utility model relates to the experimental zoology field, especially a kind of fixture that is used to prepare the damaged model of mouse femur bone.
Background technology
Tissue engineered bone is a developed recently bone transplanting rapidly product, and its osteogenic activity is high, approaches the goldstandard " from the body bone " that bone is transplanted.But the skeletonization mechanism of tissue engineered bone is still not clear, and the osteogenic activity of the tissue engineered bone that different stent materials and seed cell make up needs to detect, and these all need suitable animal model.Mostly existing bone transplantation model is larger animal, as: monkey, sheep, Canis familiaris L., pig etc., advantage is a larger animal, the skeletonization microenvironment approaches the mankind, is applicable to observe graft skeletonization effect; Shortcoming is that expense is high, operation inconvenience, and the strain of specific uses such as shortage transgenic is unfavorable for mechanism researchs such as application organizes engineering bone skeletonization mechanism.Mice is the animal model of human extensive use, and it is with low cost, and the transgenic testing line version of having set up is various, can observe the mechanism of action of range gene in osteogenetic process well.But, be applied to the mouse model of skeletonization research at present, adopt dystopy skeletonization mode more, promptly carry out skeletonization research subcutaneous the grade in non-bone tissue's environment, this can't fine simulation skeletonization microenvironment.The mice osseous tissue is because too tiny, and it is big to carry out original position skeletonization transplantation experiments difficulty, lacks good fixed apparatus and method at present.
Summary of the invention
The purpose of this utility model provides a kind of simple in structure; Anatomical parameters according to tubular bone " femur " maximum in the mice body; The fixture of design is set up the damaged model of bone of the different defect length in mouse femur stage casing, is used to observe graft skeletonization Mechanism Study.
The technical scheme that purpose adopts of this utility model is; Include the steel plate in 5 holes, two stainless steel silks; Tiing a knot behind the hole D that steel plate is passed at its described stainless steel silk A two ends respectively and the hole E is connected, and tiing a knot behind the hole A that another root stainless steel silk B passes at two ends steel plate respectively and the hole B is connected.
When using this utility model; Steel plate is placed on the distal femoral surface; Electric drill is holed on the corresponding osseous tissue of hole A, hole B, hole D, hole E, and stainless steel silk B passes respectively at two ends to tie a knot behind hole A and the hole B and is connected, and stainless steel silk A passes respectively at two ends to tie a knot behind hole D and the hole E and is connected.Steel plate is fixed on the femur, between hole B and hole D, causes femur defect, be fixed on the steel plate, prevent sliding transfer through hole C graft.Because the mice osseous tissue very carefully is difficult to prepare satisfactory lock screw; So fixing relatively firmly with the steel wire bundle that is parallel to the osseous tissue major axis, walk crosswise around the destruction and the slip of steel wire on osseous tissue that can reduce the blood fortune of destroying periosteum and bringing effectively.
The utlity model has simple and compact for structurely, easy to make, can satisfy characteristics such as test requirements document.
Description of drawings
Further specify this utility model below in conjunction with accompanying drawing.
Fig. 1 is that this utility model is bundled in the femur structure sketch map.
Among the figure: D 6-hole, C 5-hole, B 4-hole, A 3-hole, 1-steel plate 2-hole E 7-stainless steel silk A 8-stainless steel silk B 9-has damaged femur 10-graft.
The specific embodiment
As shown in Figure 1; Steel plate 1 places on the damaged femur 9; Electric drill in the hole A2, hole B3, hole D5, hole E6 corresponding damaged femur 9 borings that have are arranged; Stainless steel silk A7 passes respectively at two ends to tie a knot behind hole E6 and the hole D5 and is connected, and stainless steel silk B8 passes respectively at two ends to tie a knot behind hole A2 and the hole B3 and is connected, and injects graft 10 through hole C4.
Steel plate 1 can adopt titanium alloy material to process.

Claims (1)

1. fixture that is used to prepare the damaged model of mouse femur bone; Include the steel plate (1) in 5 holes, two stainless steel silks; It is characterized in that the hole D (5) that passes steel plate (1) respectively in described stainless steel silk A (7) two ends is connected with the knotting of hole E (6) back, the hole A (2) that another root stainless steel silk B (8) passes at two ends steel plate (1) respectively afterwards ties a knot with hole B (3) and is connected.
CN2011203740461U 2011-09-30 2011-09-30 Fixing device used for preparing mouse femoral bone impairment model Expired - Fee Related CN202288527U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2011203740461U CN202288527U (en) 2011-09-30 2011-09-30 Fixing device used for preparing mouse femoral bone impairment model

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2011203740461U CN202288527U (en) 2011-09-30 2011-09-30 Fixing device used for preparing mouse femoral bone impairment model

Publications (1)

Publication Number Publication Date
CN202288527U true CN202288527U (en) 2012-07-04

Family

ID=46357526

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2011203740461U Expired - Fee Related CN202288527U (en) 2011-09-30 2011-09-30 Fixing device used for preparing mouse femoral bone impairment model

Country Status (1)

Country Link
CN (1) CN202288527U (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105640636A (en) * 2016-02-16 2016-06-08 西安市红会医院 Method for adopting loop steel plate for treating ulna coracoid process fractures
CN110893127A (en) * 2019-10-15 2020-03-20 杭州华迈医疗器械有限公司 Animal thighbone surgery positioning fixing device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105640636A (en) * 2016-02-16 2016-06-08 西安市红会医院 Method for adopting loop steel plate for treating ulna coracoid process fractures
CN110893127A (en) * 2019-10-15 2020-03-20 杭州华迈医疗器械有限公司 Animal thighbone surgery positioning fixing device

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Legal Events

Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20120704

Termination date: 20160930