CN202226863U - Cell culture dish - Google Patents
Cell culture dish Download PDFInfo
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- CN202226863U CN202226863U CN 201120326075 CN201120326075U CN202226863U CN 202226863 U CN202226863 U CN 202226863U CN 201120326075 CN201120326075 CN 201120326075 CN 201120326075 U CN201120326075 U CN 201120326075U CN 202226863 U CN202226863 U CN 202226863U
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- culture
- hole
- cell culture
- culture dish
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/12—Well or multiwell plates
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- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Clinical Laboratory Science (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
The utility model belongs to the technical field of cell culture dishes used in the field of medicine or biology researches, aims at changing a culture dish on which culture holes are absolutely isolated in conventional cell culture, provides a cell culture dish used for researches on mutual communication and effect of information among cells, and provides a research tool for researching an information transduction mechanism and signal molecule screening among the cells. The cell culture dish comprises a plurality of culture holes, communicating areas are arranged among a group of culture holes requiring communication, communicating plates are arranged between the culture holes and the communicating areas, and the communicating plates are provided with communicating holes. The cell culture dish has the advantages of widening the research field of the cell culture, creating a research method of external joint culture of different eukaryotic cells and being an important tool for the researches on an internal cell level mechanism.
Description
Technical field
The utility model belongs to the technical field of the Tissue Culture Dish of medical science or the use of biological study field.
Background technology
Cell culture technology is widely used in medical science and biological study and Application Areas.Usually, use Tissue Culture Dish carrying liquid substratum, cell is adherent growth or suspension growth in liquid.Tissue Culture Dish commonly used can be divided into flat and round bottom (U type and V-type) according to the difference of bottom shape; The hole count of culture hole has 6,12,24,48,96,384,1536 holes etc.; Difference according to material has Terasaki plate and ordinary cells culture plate.Decide according to the type of culturing cell, required volume of culture and different experiment purposes during concrete the selection.As shown in Figure 1.
But these Tissue Culture Dishs have a common characteristic, promptly definitely separate between each culture hole, do not allow communicating with each other and acting on of cell information between different culture hole.
Summary of the invention
The purpose of the utility model is to change in the conventional cell cultures with the absolute petridish of separating between culture hole and culture hole; Foundation is used for iuntercellular information communicates with each other and acts on research and use Tissue Culture Dish, for studying iuntercellular information Transduction Mechanism and signaling molecule examination research tool is provided.
The utility model adopts following technical scheme to realize:
A kind of Tissue Culture Dish comprises some culture hole, it is characterized in that being provided with the exchanging area between one group of alternative culture hole of needs, and the interchange plate is set between each culture hole and the exchanging area, has on the described interchange plate to exchange the hole.
One preferred version of the utility model, but the exchanging area is provided with the power resources of drive its internal liquid-flow.
Another preferred version of the utility model, described power resources are for driving the gas source of liquid-flow in the exchanging area.
Another preferred version of the utility model, described power resources are whipped-up structure.
Another preferred version of the utility model, the hole wall that exchanges plate and culture hole is set to one.
Another preferred version of the utility model exchanges the hole wall socket connection of plate and culture hole.
The described Tissue Culture Dish of the utility model can also be used for the cultivation of uniting of different cells in vitro except that the eukaryotic cell vitro culture function with conventional Tissue Culture Dish.This different cells in vitro is united cultivation and can be used for the cell Related Signaling Mechanisms relevant with the intercellular signal molecule; Can be used for tumour cell to normal cytosis effect and Mechanism Study, also can be used for the specific tumors cell aggressive research of a certain body healthy tissues etc.
The utlity model has following beneficial effect: having expanded the research field of cell cultures, created the external research method of uniting cultivation of different eukaryotic cells, is the important tool of carrying out the research of cells in vivo level mechanisms.
Description of drawings
Fig. 1 is 6 culture hole petridish for the structural representation of the existing Tissue Culture Dish of using always.
Fig. 2 exchanges the structural representation of plate for the utility model.
Fig. 3 is the structural representation of the utility model.
Fig. 4 is the different shape synoptic diagram of the utility model culture hole.
Among the figure: the 1-culture hole, the 2-hole wall, the 3-exchanging area, 4-exchanges plate, and 5-exchanges hole, 6-power resources.
Embodiment
Further specify in conjunction with the embodiment of accompanying drawing to the utility model, embodiment is used for explaining the utility model, rather than it is done any restriction.
Tissue Culture Dish comprises some culture hole, and one group of culture hole comprises two or more; One group of alternative culture hole 1 of needs; Each culture hole 1 be centered close to same circumference setting, be provided with exchanging area 3 between the culture hole 1, be provided with between each culture hole 1 and the exchanging area 3 and exchange plate 4; Have on the described interchange plate 4 and exchange hole 5, it is mobile mutually that interchange hole 5 allows the liquid between different culture hole to comprise its composition (like informational molecules such as protein molecules).
But exchanging area 3 is provided with the power resources 6 of drive its internal liquid-flow.Power resources are for driving the gas source of liquid-flow in the exchanging area.Power resources also can be the mechanical type whipped-up structure.Power resources also can be micropumps.
The hole wall 2 that exchanges plate 4 and culture hole can be set to one.Each aperture that exchanges the interchange hole on the plate can be identical, also can be different.
The hole wall 2 that exchanges plate 4 and culture hole also can socket connection, and the interchange plate in different aperture informations hole can be changed.Described one group of mutual alternative culture hole can be supporting some groups exchange plates, the aperture that supporting each group exchanges plate has nothing in common with each other.Every group of each aperture that exchanges the interchange hole on the plate that exchanges in the plate can be identical, also can be different.
Petridish is provided with the petridish lid arrangement in addition, also can not be provided with.Petridish and/or interchange plate, its material can be Vilaterm, SE, PS, polyester, silicon based polymer or polyolefine.The shape of the culture hole of petridish can be circle, ellipse, square, rectangle or half elliptic.
Claims (6)
1. Tissue Culture Dish; Comprise some culture hole (1); It is characterized in that being provided with between one group of alternative culture hole of needs (1) exchanging area (3), be provided with between each culture hole (1) and exchanging area (3) and exchange plate (5), have on the described interchange plate (5) and exchange hole (5).
2. Tissue Culture Dish according to claim 1, it is characterized in that exchanging area (3) but be provided with the power resources (6) of drive its internal liquid-flow.
3. Tissue Culture Dish according to claim 2 is characterized in that described power resources (6) are for driving the gas source of liquid-flow in the exchanging area.
4. Tissue Culture Dish according to claim 2 is characterized in that described power resources (6) are whipped-up structure.
5. according to claim 1 or 2 or 3 or 4 described Tissue Culture Dishs, it is characterized in that the hole wall (2) that exchanges plate (5) and culture hole is set to one.
6. according to claim 1 or 2 or 3 or 4 described Tissue Culture Dishs, it is characterized in that exchanging hole wall (2) socket connection of plate (5) and culture hole.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201120326075 CN202226863U (en) | 2011-09-01 | 2011-09-01 | Cell culture dish |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201120326075 CN202226863U (en) | 2011-09-01 | 2011-09-01 | Cell culture dish |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202226863U true CN202226863U (en) | 2012-05-23 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201120326075 Expired - Fee Related CN202226863U (en) | 2011-09-01 | 2011-09-01 | Cell culture dish |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202226863U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102329726A (en) * | 2011-09-01 | 2012-01-25 | 山西医科大学 | Cell culture dish |
| CN108660066A (en) * | 2018-05-24 | 2018-10-16 | 黄河科技学院 | Preclinical medicine pathogen culture ware |
| CN115651841A (en) * | 2022-11-09 | 2023-01-31 | 昆明医科大学第一附属医院 | Device and method for co-culturing multiple cells of retina |
-
2011
- 2011-09-01 CN CN 201120326075 patent/CN202226863U/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102329726A (en) * | 2011-09-01 | 2012-01-25 | 山西医科大学 | Cell culture dish |
| CN102329726B (en) * | 2011-09-01 | 2016-03-02 | 山西医科大学 | Tissue Culture Dish |
| CN108660066A (en) * | 2018-05-24 | 2018-10-16 | 黄河科技学院 | Preclinical medicine pathogen culture ware |
| CN115651841A (en) * | 2022-11-09 | 2023-01-31 | 昆明医科大学第一附属医院 | Device and method for co-culturing multiple cells of retina |
| CN115651841B (en) * | 2022-11-09 | 2023-11-10 | 昆明医科大学第一附属医院 | Device and method for co-culturing multiple cells of retina |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120523 Termination date: 20160901 |