Mass spectrometer
Technical field
The utility model relates to mass spectrometer, and particularly can make the center of ion trap and the electrical potential difference between electron source is the mass spectrometer of steady state value.
Background technology
Ion trap is a kind of mass analyzer of function admirable, the basic principle that it carries out quality analysis be at first with the ion binding of different mass-to-charge ratioes in ion trap, distinguish out through the ion of electric field action then different mass-to-charge ratioes, reach the purpose of quality analysis.Ion strap mass analyzer have little, the easy processing of volume, to vacuum degree require low, maintenance cost is low, highly sensitive and can carry out numerous advantages such as multi-stage ms analysis; Therefore; Be widely used in the various mass spectrometers based on ion strap mass analyzer, particularly miniaturization or portable mass spectrometer.
Fig. 1 shows the mass spectrometric basic block diagram that generally adopts in the prior art, and is as shown in Figure 1, comprises the electron source 105, electron lens 104,3D ion trap, the detector 108 that set gradually, and radio-frequency power supply 106 and electronic gate control unit 107 etc.During the work of this ion trap, apply the radio-frequency voltage of alternation on the ring electrode 101 of ion trap, about two endcap electrodes 102 and 103 ground connection.
Fig. 2 shows the work sheet of electronic gate in the prior art, and is as shown in Figure 2, and in the ionization stage in the ion trap course of work, electronic gate all is in opening, and electronics all can get into ion trap internal ionization neutral substance in all stage.
The Ionized basic process of neutral substance is: have the electron bombard neutral substance of certain kinetic energy, cause neutral substance to lose electronics or chemical bond rupture, thereby form molecular ion or fragment ion.In ionization process, the fragment ion of formation and the kinetic energy of electronics have directly gets in touch, and therefore, the mass spectrogram in the standard spectrum storehouse all is to use the electronics (70eV) of constant kinetic energy to go to bombard that neutral substance obtains.
According to the working method of Fig. 2 owing to apply the radio-frequency voltage of alternation on the ion trap ring electrode 101, and about two endcap electrode ground connection, this moment, center, the field electromotive force of ion trap was not 0, but V/2, wherein V is the amplitude (half-peak value) of radio-frequency voltage.The electromotive force of the electromotive force that the kinetic energy that the electronics that filament is launched has should equal filament itself and the neutral substance position of being bombarded poor; Therefore; In this case; Even the electromotive force of filament is constant, the kinetic energy of electron bombard neutral substance also can be along with the RF change in voltage, and above-mentioned control mode can be brought following problem:
1, the electronic kinetic energy amplitude of variation is very big, and the matching degree in the fragment ion peak of generation and standard spectrum storehouse is very low, has increased material difficulty qualitatively;
2, electronic kinetic energy alternate has increased the uncertainty in the ionization process, and it is relatively poor therefore to obtain mass spectrogram repeatability.
The utility model content
In order to solve the deficiency in the above-mentioned prior art scheme, the utility model provides a kind of accuracy of measurement high mass spectrometer, and the method for work of the high mass spectrometer of a kind of accuracy of measurement also is provided.
The purpose of the utility model realizes through following technical scheme:
Mass spectrometer comprises electron source, electronic gate and ion trap; Said mass spectrometer also comprises:
Detecting unit, said detecting unit are used to detect the work signal of telecommunication of said ion trap, and are sent to control unit;
Control unit; Said control unit is used for controlling said electronic gate according to the said work signal of telecommunication that receives; Thereby make that said electronic gate is opened, otherwise closes said electronic gate when the center of said ion trap and the electrical potential difference between said electron source are definite value.
According to above-mentioned mass spectrometer, as preferably, said detecting unit is used to detect the phase place or the amplitude of the said work signal of telecommunication, and when detecting same phase or amplitude such as equidirectional, said control unit is opened said electronic gate, otherwise closes electronic gate.
According to above-mentioned mass spectrometer, as preferably, the said work signal of telecommunication is the sine wave or the square wave signal of telecommunication.
According to above-mentioned mass spectrometer, as preferably, when said detection to the said work signal of telecommunication when being zero, said control unit is opened said electronic gate, otherwise closes said electronic gate
Above-mentioned mass spectrometer is applied in the mass spectral analysis, and its workflow is:
(A1) detect the work signal of telecommunication of ion trap, and be sent to control unit;
(A2) control unit is controlled said electronic gate according to the said work signal of telecommunication that receives; So that when the center of said ion trap and the electrical potential difference between electron source are definite value; Said electronic gate is opened, thereby makes said electron source electrons emitted get into said ion trap with constant kinetic energy;
(A3) test substance is got into electronic impact and the ionization of said ion trap, and the ion of generation is ejected said ion trap;
(A4) detect the ion that is ejected ion trap, after analyzing, know the information of test substance.
As preferably, the phase place or the amplitude of the said work signal of telecommunication of said detection, when detecting same phase or amplitude such as equidirectional, said control unit is opened said electronic gate, otherwise closes said electronic gate.
As preferably, the said work signal of telecommunication is the sine wave or the square wave signal of telecommunication.
As preferably, when said detection to the said work signal of telecommunication when being zero, said control unit is opened said electronic gate, otherwise closes said electronic gate.
Compared with prior art, the beneficial effect that the utlity model has is:
Just open electronic gate when 1, only electrical potential difference is definite value between ion trap center and electron source, otherwise close said electronic gate, the feasible kinetic energy that gets into the electronics of ion trap keeps constant basically.Therefore, this method can improve the matching degree in gained mass spectrogram and standard spectrum storehouse, thereby improves accuracy in detection.
2, avoid the kinetic energy change of the electronics of the entering ion trap that the RF alternating voltage causes, improved the repeatability of gained mass spectrogram.
Description of drawings
With reference to accompanying drawing, the disclosure of the utility model will be easier to understand.Those skilled in the art are understood that easily: these accompanying drawings only are used to illustrate the technical scheme of the utility model, and are not to be intended to the protection range of the utility model is constituted restriction.Among the figure:
Fig. 1 is a mass spectrometric basic block diagram in the prior art;
Fig. 2 is the control sketch map of electronic gate in the prior art;
Fig. 3 is the basic block diagram according to the mass spectrometer of the utility model embodiment 1;
Fig. 4 is the control sketch map according to the electronic gate of the utility model embodiment 1;
Fig. 5 is the control sketch map according to the electronic gate of the utility model embodiment 1;
Fig. 6 is the flow chart according to the method for work of the utility model embodiment 1.
Embodiment
Fig. 3-6 and following declarative description the optional execution mode of the utility model how to implement with instruction those skilled in the art and reproduce the utility model.In order to instruct the utility model technical scheme, simplified or omitted some conventional aspects.Those skilled in the art should understand that the modification or the replacement that are derived from these execution modes will be in the scopes of the utility model.Those skilled in the art should understand that following characteristics can make up to form a plurality of modification of the utility model in every way.Thus, the utility model is not limited to following optional execution mode, and is only limited claim and their equivalent.
Embodiment 1:
Fig. 3 has schematically provided the basic block diagram of the mass spectrometer of the utility model embodiment.As shown in Figure 3, said mass spectrometer comprises:
Electron source 205, said electron source is used for emitting electrons.
Ion trap, said ion trap is used for the ionization test substance, constraint ion and ejection ion.Said ion trap can adopt the 3D ion trap, specifically comprises ring electrode 201, endcap electrode 202,203.Certainly can also adopt other types, these all are the state of the art.
Power supply 206, said power supply is used to drive said electron source and ion trap, wherein for ion trap sine voltage is provided.
Detector 208, said detector are used to receive the ion that ejects from said ion trap.
Analytic unit, said analytic unit are used to analyze the signal that the said detector that receives sends, thereby know the information such as classification, content of test substance.
Whether electronic gate 204, said electronic gate are used to control the electronics that said electron source launches passes through, and specifically is arranged between said electron source and the ion trap.
Detecting unit 209, said detecting unit are used to detect the phase place of operating voltage signal of the said ion trap of said power supply output, and are sent to control unit; Said detecting unit can adopt circuit or software to realize.
Control unit 207, said control unit are used for controlling said electronic gate according to the said operating voltage signal that receives.Said control unit can adopt circuit or software to realize.
Fig. 4,5 has schematically provided the control chart of said electronic gate; Like Fig. 4, shown in 5; Concrete mode is: when detecting the work signal of telecommunication of same phase or amplitude such as equidirectional, when being zero like the said work signal of telecommunication, this moment, the center and the electrical potential difference between electron source of ion trap were definite values; Said control unit is opened said electronic gate, otherwise closes electronic gate.
Fig. 6 has schematically provided the flow chart of method of work of the mass spectrometer of the utility model embodiment.As shown in Figure 6, said method of work may further comprise the steps:
(A1) phase place of the work signal of telecommunication of detection ion trap, the said work signal of telecommunication is the sine voltage signal, and is sent to control unit;
(A2) when the working signal of amplitudes such as detected phase place is identical or equidirectional; When being zero like the said work signal of telecommunication; Like Fig. 4, shown in 5; The center of said ion trap and the electrical potential difference between electron source are definite value, and control unit is opened said electronic gate, thereby make said electron source electrons emitted get into said ion trap with constant kinetic energy; Otherwise close said electronic gate;
(A3) test substance is got into electronic impact and the ionization of said ion trap, and the ion of generation is ejected said ion trap;
(A4) detect the ion that is ejected ion trap, after analysis, know the information such as classification, content of test substance.
The benefit that reaches according to the utility model embodiment is: just open electronic gate when only electrical potential difference is definite value between ion trap center and electron source; Otherwise close said electronic gate; The feasible kinetic energy that gets into the electronics of ion trap keeps constant; Improve the matching degree in gained mass spectrogram and standard spectrum storehouse, also improved the repeatability of gained mass spectrogram.
Embodiment 2:
A kind of mass spectrometer, different with embodiment 1 is: power supply is that ion trap provides the square wave operating voltage.
The method of work of the above-mentioned mass spectrometer of present embodiment, different with embodiment 1 is: power supply is that ion trap provides the square wave operating voltage.