CN202210073U - Assay detection and judgment equipment - Google Patents
Assay detection and judgment equipment Download PDFInfo
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- CN202210073U CN202210073U CN2011202828117U CN201120282811U CN202210073U CN 202210073 U CN202210073 U CN 202210073U CN 2011202828117 U CN2011202828117 U CN 2011202828117U CN 201120282811 U CN201120282811 U CN 201120282811U CN 202210073 U CN202210073 U CN 202210073U
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Abstract
The utility model provides assay detection and judgment equipment, which comprises a photoelectric detection circuit, a processor and an optical detection device provided with a detection area and a blank area, the photoelectric detection circuit detects light reflection strength signals from the detection area and the blank area and sends the detection result to the processor, a preset threshold value changing with time is available in the processor, and the assay result is acquired through comparing the preset threshold value with the judgment value from the processor. Compared with the prior art, the assay detection and judgment equipment has the advantages of higher efficiency, accuracy in judgment and lower cost.
Description
[technical field]
The utility model relates to a kind of equipment of judging result of laboratory test, refers in particular to the chemical examination of reading by chemical examination object measured value and detects determining apparatus.
[background technology]
Many equipment to the assay analysis has been arranged on the market,, be used to measure HCG like a kind of cross-flow type immunoassay device; Belong to disposable use test strips, need the user to read the result, have subjectivity to a certain degree; And need add timer in addition; And the result shows with color, and result's color can be deepened along with increasing progressively of time, thereby can influence the effect of interpretation; Another disclosed device utilizes optical means to obtain the result, and analytical test strip is inserted reader, makes test-strips be positioned on the optical element of reader, from the rayed test strips of light emitted, and with photodetector detection of reflected light or transmitted light.Typically, this reader contains a light emitting diode at least, and each light emitting diode all is provided with corresponding photodetector, belongs to muptiple-use use electronic pen.Similar this analytical instrument; Need assay readings device and test-strips are carefully located; This be because the visible signal that in detection zone and control zone, forms quite a little less than, so the reading that little displacement will influence detecting device significantly takes place for corresponding light detection zone in detection or control zone.In addition photodetector will with test-strips near being very important because the light quantity that photodiode is caught is quite few, and signal intensity observes inverse square law usually, therefore, it increases along with the distance between test-strips and the photodetector and reduces rapidly.So, just need the user that prod and analysis result reader are carefully located, especially housed device.And nonexpondable analytical instrument is particularly this small-sized, be easy to cause dislocation because of the insertion repeatedly of test strips, and the dislocation of trace will and then produce error.
The method of another kind of active immunity equipment; Through a crossing current carrier additional electrode is provided, detects whether there is fluid on this carrier, and produce a signal and connect said detection. electronics; Show testing result; But in different tests, liquid has nothing in common with each other along the speed of carrier flow, and dissimilar flow rate of liquid characteristics can cause reading inaccurate result.Because wick and the inconsistent attribute of porous water-permeable membrane material therefor, the optimum time point that reads the result also can be different.Corresponding a kind of result of laboratory test readout equipment is used to read the result of laboratory test of using the liquid transfer carrier to carry out, how to confirm the best reading problem in period to solving, but still can't resolve the problem of different fluid different in flow rate standard.Simultaneously, some check and analysis instrument detecting overlong time requires to reach 15 minutes like the commerce crossing current testing tool based on chemical examination that detects heart injury and could accomplish said chemical examination.In other situation, particularly conceived test, the user expects knowledge of result as early as possible naturally.
Also have a kind of Calculation Method, set two threshold values, through comparing the relation between detected value and the threshold value and then drawing the result of detection.But because the reaction of design possibly need just can reach in the certain hour state measured of balance, too fast obtains a result, and may cause result's instability.Simultaneously, this utility model is not mentioned the problem that threshold value is whether variable.Get according to research institute, different according to the duration, the humidity of paper slip can change, and threshold value also can change, and fixing threshold value will cause certain error.And, only measure detection zone and confirm the result according to the accumulation of its signal, lack the clear area contrast, can not go out the background influence factor, error can strengthen.In addition, operation improperly takes place to install in the replacement of paper slip easily, like this to causing misjudgment because of the error of any to the responsive reader of light path originally.
[summary of the invention]
The purpose of the utility model is to provide a kind of efficient height, accuracy of judgement, chemical examination that cost is low to detect determining apparatus.
For realizing the utility model purpose, following technical scheme is provided:
The utility model provides a kind of chemical examination to detect determining apparatus, and it comprises photoelectric detective circuit and processor, and the optical detection apparatus that is used to measure the chemical examination signal; Be provided with detection zone and clear area in the optical detection apparatus; Said photoelectric detective circuit detects the light reflection strength signal of detection zone and clear area, and detection feedback information gives processor, and this processor includes time control module, threshold modifying module and the data comparison module that is connected; This time control module is connected with threshold modifying module, photoelectric detective circuit respectively; This threshold modifying module, photoelectric detective circuit also are connected with data comparison module simultaneously, and the threshold modifying module receives the signal of time control module, and transmit threshold data to data comparison module; Photoelectric detective circuit receives the signal of time control module; And detected value is sent to data comparison module, data comparison module receives from the threshold data of threshold modifying module with from the detected value of photoelectric detective circuit, and relatively draws result of determination.Specifically; The threshold modifying module is revised threshold value and is sent to data comparison module according to the signal of time control module; Photoelectric detective circuit comes according to the signal of time control module that regularly detecting the gained detected value is sent to data comparison module, and data comparison module will detect data and calculate and relatively draw result of determination with corresponding threshold value.
Wherein, this threshold modifying module comprises start test module, time detecting module, threshold value update module, the threshold value output module that is connected.After this threshold modifying module detects open state (being that circuit is connected) through the start test module; The time detecting module detects the time signal that the time control module is sent; According to this time signal; The threshold value update module is upgraded threshold value according to Preset Time and changes of threshold relation, and the passing threshold output module exports the threshold value of upgrading to said data comparison module.
This data comparison module comprises blank value protection module, measured value input and the protection module, the slope calculating module that are connected, relatively reaches determination module, the result preserves module; The numerical value of this blank value protection module, measured value input and protection module inputs to the slope calculating module; The result of this slope calculating module inputs to and relatively reaches determination module and threshold value compares, and result of determination is saved to the result and preserves module.
Preferably, this chemical examination detects determining apparatus and further comprises the display device that shows detected state or result of determination, and this display device is connected with processor.Preferably, this display device is the LCD LCDs.As preferred embodiments, dodge pattern with hourglass on this LCD LCDs and represent detected state.
Preferably, this chemical examination detection determining apparatus further comprises the auditory tone cues device that is connected with processor.Can represent detected state or result of determination through sound.
This equipment is used to read result of laboratory test to detect existing and content of target assay; The existence of wherein said target assay causes a kind of reaction with not existing; Cause a signal to be accumulated with the mode of time to time change; This equipment is used for confirming signal accumulative total semi-invariant, be used to calculate decision content with and with threshold ratio, and expression result of laboratory test.So this equipment can guarantee when going out the result as early as possible, guarantees the result who detects.Avoid the last appearance back time too short, and shown deviation, or the drawback of waits for too long.Simultaneously, also take into full account the factor of test strips dehydration, set the threshold value of floating, can draw testing result the most accurately.And the setting of clear area can be removed background more, reduces the error that detects.
The chemical examination that the utility model adopts said chemical examination to detect determining apparatus detects decision method, is used to detect the existence and the content of specific assay, carries out said chemical examination to cause a kind of reaction; The mode that this reaction causes a chemical examination signal to change with the time is accumulated in the detection zone of said optical detection apparatus; Photoelectric detective circuit is launched light to detection zone and clear area, and the light reflection strength signal of detection zone and clear area is detected, and detection feedback information is given processor; Wherein
Processor is preset with time dependent threshold X,
Processor is confirmed chemical examination signal accumulation amount according to detection zone and the clear area light reflection strength signal before application of sample and behind the application of sample that photoelectric detective circuit fed back, and calculates corresponding decision content K;
Be greater than or equal to threshold X at that time at determined decision content K, perhaps when time t satisfied the Preset Time value, said decision content K did not reach said threshold X, when perhaps recording signal and can't provide judgement, and ecbatic.
Preferably, if within a certain period of time, through reaction, said decision content K is greater than or equal to the threshold X that sets and (is that K>=X), horse back is exported first consequential signal so, and finishes chemical examination; After if time t reaches schedule time value t4, said decision content K then exports second consequential signal and finishes chemical examination all less than the threshold X that sets (be K<X); If occur comparing state, then export the third result, finish chemical examination.The incommensurable state of said appearance generally is meant the situation that application of sample occurs not having.Wherein t4 decides according to actual conditions, can obtain result of laboratory test comparatively accurately after can from experimental data, knowing time t4.
Preferably, in setting-up time t4,, then repeat detection, calculating and the comparison of a new round if said decision content is lower than preset threshold.
Preferably, said first result is a positive result, and said second result negates the result, and the 3rd result can't judge or result that sample size is not enough.
Preferably, processor was confirmed chemical examination signal accumulation amount before said reaction reaches balance.Because this assay chemistry used reaction required time is longer; If wait for react completely after again reading of data then expend time in longer; And application of sample amount and the linear ratio of time relation in the course of reaction; Therefore can in course of reaction, quantize to detect to the chemical examination signal, thereby obtain definite analysis data according to application of sample amount and time relation ratio; In addition; After reaction reached balance, As time goes on the humidity of detection zone can reduce, and the detection zone color can be deepened gradually; But the chemical examination signal of reaction does not increase; Detected signal like this is just very possible inconsistent with the real reaction result, and detection zone change in color and reacting dose are proportional in the course of reaction, can truly reflect the definite result that assay chemistry used is reacted at detected signal of this stage.
Preferably; This decision content K is: scanned before application of sample by detection zone and clear area and read to draw numerical value T0, B0; Detection zone is read value T1 with clear area scanning after second, B1 compares respectively with application of sample N again; Draw the ratio T1/T0 of detection zone and the ratio B1/B0 of clear area respectively, deduct the ratio of clear area again with the ratio of detection zone, thereby draw decision content K=T1/T0-B1/B0.Wherein said N can select according to reacting dose and time relation that the concrete chemical examination that experiment draws is reacted second.
Preferably, this detecting operation carried out according to the time of setting.
Preferably, when the time, t reached t1 behind application of sample, time of occurrence was reminded mark, preferably adopts auditory tone cues, with prompting application of sample reaction beginning.Time of responding for from the application of sample to the detection zone, beginning of estimating according to actual conditions of t1 wherein.
Preferably, after time t reaches t2 behind the application of sample, read detection zone and clear area numerical value T, B; If the situation of application of sample occurs not having; Just T=T0, B=B0 then export the third result, and this third result can adopt the miscue mode to export; Specifically can export through showing, and/or through auditory tone cues output.
Preferably, at interval the t3 time is read detection zone and clear area numerical value T1, B1 behind above-mentioned t2 time reading numerical values T, B, according to this numerical value T1, B1 computational discrimination value K, and compares with threshold X.In setting-up time t4, if said decision content K is lower than preset threshold X, then repeat the operation of a new round, promptly every interval t3 time detecting T1, B1, computational discrimination value K and and threshold X compare.
The contrast prior art the utlity model has following advantage:
The compared with prior art efficient raising of the utility model result of laboratory test checkout equipment, accuracy of judgement, cost are lower.The utility model can guarantee when going out the result as early as possible, guarantees the result who detects.Avoid the last appearance back time too short, and shown deviation, or the drawback of waits for too long.Simultaneously, also take into full account the factor of test strips dehydration, set the threshold value of floating, can draw testing result the most accurately.
[description of drawings]
Fig. 1 is the framed structure synoptic diagram that the chemical examination of the utility model detects determining apparatus;
Fig. 2 detects the synoptic diagram of threshold modifying module in the determining apparatus for the utility model chemical examination;
Fig. 3 detects the synoptic diagram of data comparison module in the determining apparatus for the utility model chemical examination;
Fig. 4 detects the specific embodiment process flow diagram of decision method for the utility model chemical examination.
[embodiment]
See also Fig. 1 ~ 3; The chemical examination of accompanying drawings the utility model detects determining apparatus; It comprises photoelectric detective circuit and processor, and the optical detection apparatus that is used to measure the chemical examination signal, is provided with detection zone and clear area in the optical detection apparatus; Said photoelectric detective circuit detects the light reflection strength signal of detection zone and clear area; And detection feedback information gives processor, and this processor includes time control module, threshold modifying module and the data comparison module that is connected, and this time control module is connected with threshold modifying module, photoelectric detective circuit respectively; This threshold modifying module, photoelectric detective circuit also are connected with data comparison module simultaneously; The threshold modifying module is revised threshold value and is sent to data comparison module according to the signal of time control module, and photoelectric detective circuit comes according to the signal of time control module that regularly detecting the gained detected value is sent to data comparison module, and data comparison module will detect data and calculate and relatively draw result of determination with corresponding threshold value.
The display device output of this result of determination through being connected with processor, this display device can also show detected state, in the present embodiment, this display device is the LCD LCDs.As preferred embodiments, dodge pattern with hourglass on this LCD LCDs and represent detected state.
This chemical examination detects determining apparatus and further comprises the auditory tone cues device that is connected with processor.Can represent detected state or result of determination through sound.For example in certain hour behind the application of sample, can send the sound and remind the beginning trace routine, perhaps when the result exports, also can point out through the sound through the auditory tone cues device.
As shown in Figure 2, wherein this threshold modifying module comprises start test module, time detecting module, threshold value update module, the threshold value output module that is connected.After this threshold modifying module detects open state (being that circuit is connected) through the start test module; The time detecting module detects the time signal that the time control module is sent; According to this time signal; The threshold value update module is upgraded threshold value according to Preset Time and changes of threshold relation, and the passing threshold output module exports the threshold value of upgrading to said data comparison module.
As shown in Figure 3; This data comparison module comprises blank value protection module, measured value input and the protection module, the slope calculating module that are connected, relatively reaches determination module, the result preserves module; The numerical value of this blank value protection module, measured value input and protection module inputs to the slope calculating module; The result of this slope calculating module inputs to and relatively reaches determination module and threshold value compares, and result of determination is saved to the result and preserves module.
This equipment is used to read result of laboratory test to detect existing and content of target assay; The existence of wherein said target assay causes a kind of reaction with not existing; Cause a signal to be accumulated with the mode of time to time change; This equipment is used for confirming signal accumulative total semi-invariant, be used to calculate decision content with and with threshold ratio, and expression result of laboratory test.So this equipment can guarantee when going out the result as early as possible, guarantees the result who detects.Avoid the last appearance back time too short, and shown deviation, or the drawback of waits for too long.Simultaneously, also take into full account the factor of test strips dehydration, set the threshold value of floating, can draw testing result the most accurately.And the setting of clear area can be removed background more, reduces the error that detects.
This equipment can guarantee when going out the result as early as possible, guarantees the result who detects.Avoid the last appearance back time too short, and shown deviation, or the drawback of waits for too long.Simultaneously, also take into full account the factor of test strips dehydration, set the threshold value of floating, can draw testing result the most accurately.And the setting of clear area can be removed background more, reduces the error that detects.
In the present embodiment, said chemical examination is the chemical examination of crossing current row, and the sample that wherein possibly comprise specific assay is applied to a liquid delivery device (normally porous infiltration carrier), and can move along this device.
The chemical examination that the utility model adopts said chemical examination to detect determining apparatus detects decision method, is used to detect the existence and the content of specific assay, carries out said chemical examination to cause a kind of reaction; The mode that this reaction causes a chemical examination signal to change with the time is accumulated in the detection zone of said optical detection apparatus; Photoelectric detective circuit is launched light to detection zone and clear area, and the light reflection strength signal of detection zone and clear area is detected, and detection feedback information is given processor; Wherein
Processor is preset with time dependent threshold X,
Processor is confirmed chemical examination signal accumulation amount according to detection zone and the clear area light reflection strength signal before application of sample and behind the application of sample that photoelectric detective circuit fed back, and calculates corresponding decision content K;
Be greater than or equal to threshold X at that time at determined decision content K, perhaps when time t satisfied the Preset Time value, said decision content K did not reach said threshold X, when perhaps recording signal and can't provide judgement, and ecbatic.
Specific embodiment sees also Fig. 4, behind application of sample, connects photoelectric detective circuit, and detect and write down initial value T0, the B0 of detection zone and clear area this moment, and when time t reached 10 seconds behind application of sample, time of occurrence was reminded mark, adopts the reaction of auditory tone cues prompting application of sample to begin.
After time t reaches 75 seconds behind the application of sample, read detection zone and clear area numerical value T, B, judged whether application of sample; If the situation of application of sample occurs not having, just miscue then appears in T=T0, B=B0; Export the third result, can export through showing, and/or through auditory tone cues output; If application of sample arranged, promptly T, B and T0, B0 are different, then get into next step.
Read at interval detection zone and clear area numerical value T1, B1 again after 20 seconds,, and compare,, then export first kind of result, positive result as if K >=X with threshold X according to this numerical value T1, B1 computational discrimination value K (K=T1/T0-B1/B0).
If in setting-up time 4 minutes, if said decision content K is lower than preset threshold X, promptly < X then repeats the operation of a new round to K, and the 20 seconds time detecting T1 in promptly every interval, B1 recomputate decision content K and compare with threshold X.
If time t >=4 minute, decision content K still is lower than preset threshold X, then exports second kind of result, negative decision.
The signal of in the chemical examination process, accumulating can be any signal that is fit to above-mentioned purpose.For simplicity, said signal accumulation comprises the formation or the accumulation (like the result of color reaction) of the material of easy detection.More specifically, said chemical examination preferably comprises the accumulation of label, and normally label is in the accumulation of detection zone.Described label can be colored particles such as enzyme, radio-label, luciferin, collaurum, colored latex.Special, the employing that said chemical examination scheme is specific the collaurum functional microsphere thing that serves as a mark.
Usually, the specific assay in sample can cause the accumulation of said signal, but in some cases, waits in the reaction like competition, and there is not the accumulation that can cause relevant signal in described specific assay.
Usually, if within a certain period of time, through reaction, said decision content is greater than or equal to the threshold value that sets, and exports first consequential signal so at once, is acknowledge signal, and finishes chemical examination.
If in the regular hour, said decision content is less than the threshold value that sets, and then exporting second consequential signal is negative acknowledge character (NAK), and finishes chemical examination.
If the added sample, the sample volume of the sample need not detected, the display can not determine the result and by a long GOD sound.
Its decision content is to be scanned before application of sample by detection zone and clear area to read to draw numerical value, again with application of sample after the scanning of detection zone and clear area read value and compare respectively, deduct the ratio of detection zone again with the ratio of clear area.
So this equipment can guarantee when going out the result as early as possible, guarantees the result who detects.Avoid the last appearance back time too short, and shown deviation, or the drawback of waits for too long.Simultaneously, also take into full account the factor of test strips dehydration, set the threshold value of floating, can draw testing result the most accurately.And the setting of clear area can be removed background more, reduces the error that detects.
The reaction that causes signal accumulation can be any suitable reaction, like the conventional chemical reaction between two kinds of chemical entities, integrated enzyme reaction or immune coupling reaction.Preferred immune coupling reaction will comprise the combination of at least one biomolecule.
Preferred reaction comprises that specific reagent combines in label complex and the detectable bar that is fixed on detection zone, and label is accumulated in the land.
Be inserted into the sample liquid the inside at the suction lining bar, after sample was seeped into and inhales on the lining bar, the resistance of circuit changed, and reading device is activated, simultaneously the initial signal value of scan test section and clear area.Overall process is accomplished automatically, but also can set up a switch or button cooperation completion.
After reader activated, the preset certain reaction time let the object in the sample fully react display screen demonstration this moment funnel pattern with the label reagent on the test-strips.Behind the interval (like 16s), scan test section and blank value calculate decision content according to the formula that designs for the second time, and the relation of the value of comparing to determine and threshold value at the fixed time.If decision content is greater than threshold value at that time, so, chemical examination safety stops, the output positive result; If decision content is less than threshold value at that time, new scanning, calculating and the comparison of a heavy new round after preset time so, threshold value also substitutes the new threshold value for setting; If this moment, decision content was greater than threshold value at that time, so, chemical examination safety stops; The output positive result, if decision content is less than threshold value at that time, again circulation after preset time so.If in the time of setting (promptly reaching terminal point t), decision content still is less than threshold value at that time, is judged to be negative decision so.
Typically, at terminal point t, this equipment thinks that chemical examination finishes, but the t point might not be the point that reaction is accomplished.
Can judging with reference to particular point in time of terminal point t aspect promptly joined by sample liquid and inhales on the lining bar reader and be activated and begin to calculate, and preferably, t selects 1-6 minute.
Programme in the processor, make and measure for repeating under the situation that obtains net result.In simple embodiment, measuring can repetition.Before terminal point, repeat one or many, surpass preset threshold up to decision content.
The utility model equipment preferably includes a clock or other timing devices, makes it possible to automatically point measurement at the fixed time, and does not need other users' input or operation.
Like this, can be at the initial time point measurement, if be necessary, any desired interval duplicate measurements after it surpasses preset threshold up to decision content.
Clock mainly is the interval time that is used to set and the calculating of terminal time.Test can be carried out smoothly.
This equipment can begin to measure one or more numerical value according to the program of setting and compare.
The above is merely the preferred embodiment of the utility model, and the protection domain of the utility model is not limited thereto, and anyly all belongs within the utility model protection domain based on the equivalent transformation on the utility model technical scheme.
Claims (6)
1. a chemical examination detects determining apparatus, and it comprises photoelectric detective circuit and processor, and the optical detection apparatus that is used to measure the chemical examination signal; Be provided with detection zone and clear area in the optical detection apparatus, said photoelectric detective circuit detects the light reflection strength signal of detection zone and clear area, and detection feedback information is given processor; It is characterized in that; Processor includes time control module, threshold modifying module and the data comparison module that is connected, and this time control module is connected with threshold modifying module, photoelectric detective circuit respectively, and this threshold modifying module, photoelectric detective circuit also are connected with data comparison module simultaneously; The threshold modifying module receives the signal of time control module; And transmitting threshold data to data comparison module, photoelectric detective circuit receives the signal of time control module, and detected value is sent to data comparison module; Data comparison module receives from the threshold data of threshold modifying module with from the detected value of photoelectric detective circuit, and relatively draws result of determination.
2. chemical examination as claimed in claim 1 detects determining apparatus, it is characterized in that this threshold modifying module comprises start test module, time detecting module, threshold value update module, the threshold value output module that is connected.
3. chemical examination as claimed in claim 2 detects determining apparatus; It is characterized in that; This data comparison module comprises blank value protection module, measured value input and the protection module, the slope calculating module that are connected, relatively reaches determination module, the result preserves module; The numerical value of this blank value protection module, measured value input and protection module inputs to the slope calculating module; The result of this slope calculating module inputs to and relatively reaches determination module and threshold value compares, and result of determination is saved to the result and preserves module.
4. chemical examination as claimed in claim 3 detects determining apparatus, it is characterized in that, it further comprises the display device that shows detected state or result of determination, and this display device is connected with processor.
5. chemical examination as claimed in claim 4 detects determining apparatus, it is characterized in that this display device is the LCD LCDs.
6. chemical examination as claimed in claim 3 detects determining apparatus, it is characterized in that it further comprises the auditory tone cues device that is connected with processor.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011202828117U CN202210073U (en) | 2011-08-05 | 2011-08-05 | Assay detection and judgment equipment |
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| CN2011202828117U CN202210073U (en) | 2011-08-05 | 2011-08-05 | Assay detection and judgment equipment |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102384890A (en) * | 2011-08-05 | 2012-03-21 | 广州万孚生物技术有限公司 | Test detecting judging device and method |
| WO2023056837A1 (en) * | 2021-10-09 | 2023-04-13 | 广东粤港澳大湾区国家纳米科技创新研究院 | Rapid drug test method, one-minute rapid drug test device, and distributed drug test system |
-
2011
- 2011-08-05 CN CN2011202828117U patent/CN202210073U/en not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102384890A (en) * | 2011-08-05 | 2012-03-21 | 广州万孚生物技术有限公司 | Test detecting judging device and method |
| CN102384890B (en) * | 2011-08-05 | 2014-04-30 | 广州万孚生物技术股份有限公司 | Test detecting judging device and method |
| WO2023056837A1 (en) * | 2021-10-09 | 2023-04-13 | 广东粤港澳大湾区国家纳米科技创新研究院 | Rapid drug test method, one-minute rapid drug test device, and distributed drug test system |
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Owner name: GUANGZHOU WONDFO BIOTECH. CO., LTD. Free format text: FORMER NAME: GUANGZHOU WONDFO BIOMEDICAL CO., LTD. |
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| CP01 | Change in the name or title of a patent holder |
Address after: 510663 Guangzhou, Luogang District Science City, litchi Road, No. 8, No. Patentee after: Guangzhou Wandfo Biotechnology Co.,Ltd. Address before: 510663 Guangzhou, Luogang District Science City, litchi Road, No. 8, No. Patentee before: Wondfo Biotech Co., Ltd. |
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Granted publication date: 20120502 |