CN202201903U - Experiment device for in-vitro analysis on cell migration - Google Patents

Experiment device for in-vitro analysis on cell migration Download PDF

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Publication number
CN202201903U
CN202201903U CN 201120352894 CN201120352894U CN202201903U CN 202201903 U CN202201903 U CN 202201903U CN 201120352894 CN201120352894 CN 201120352894 CN 201120352894 U CN201120352894 U CN 201120352894U CN 202201903 U CN202201903 U CN 202201903U
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CN
China
Prior art keywords
cell migration
vitro analysis
experiment device
pore plate
scratch
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN 201120352894
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Chinese (zh)
Inventor
李兴起
刘权
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heilongjiang Bayi Agricultural University
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Heilongjiang Bayi Agricultural University
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Priority to CN 201120352894 priority Critical patent/CN202201903U/en
Application granted granted Critical
Publication of CN202201903U publication Critical patent/CN202201903U/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

The utility model relates to an experiment device for in-vitro analysis on cell migration, which comprises a body (1) provided with a plurality of evenly distributed comb teeth (2). The experiment device for the in-vitro analysis on the cell migration utilizes a comb with a plurality of teeth to carry out scratch experiments, thereby having large handling capacity, being neat and uniform, avoiding problems of low efficiency caused by single scratch experiment carried out by operators through a gun head, greatly saving operation time and having accurate scratch positions. The experiment device for the in-vitro analysis on the cell migration can be respectively set different dimensions according to a twenty-four pore plate, a ninety-six pore plate and a three-hundred and eighty-four pore plate, thereby having wide application scope.

Description

A kind of cell migration analyzed in vitro experimental installation
Technical field
The utility model relates to the cut device that uses in the cell culture experiments, concrete is a kind of cell migration analyzed in vitro experimental installation.
Background technology
Cell migration is ubiquity in body normal physiological activity and disease take place, for example the looking for food of cell, wound wound healing, embryo's generations, neural system formation, immunoreation, cancer metastasis etc. much incidents all relate to cell migration.Cell migration is the important directions and the focus of current life science, and scientists is attempted the research through on cell migration, in the blood vessel injury reparation, stop and obtaining bigger achievement aspect the medical uses such as cancer metastasis, skin-grafting.
Scratch experiment is mainly used in research cell migration at present.Epithelial cell, keratinocyte etc. form individual layer or stratified epithelium under physiological status, under pathological states such as wound healing, cell moves, and are main with edgewise motion.Scratch experiment has been simulated this mode of motion well, and easy to operate, therefore is a good model of research cell migration.In existing scratch experiment, generally adopt aseptic plastics rifle head artificial hand to draw, this kind method has that cut is straight, the cut position is inaccurate, simultaneously shortcoming such as inefficiency.Therefore, need a kind of device that can carry out a plurality of holes while cuts, cut stationkeeping of invention.
Summary of the invention
The goal of the invention of the utility model is a kind of cell migration analyzed in vitro experimental installation to be provided to the problems referred to above, and solving present scuffing experimental device can't accurate scratching, the problem of inefficiency.
The utility model is realized through following technical scheme: a kind of cell migration analyzed in vitro experimental installation, and this device comprises body, evenly distributed on the body have many broach.
The broach both sides have shoulder respectively.
Adopt the positively effect of technique scheme: the utility model utilizes multiple tooth comb to carry out scratch experiment; Treatment capacity is big, and is uniform, avoided artificial with the single problem of carrying out the scratch experiment inefficiency of rifle head; Practiced thrift the running time greatly, and the cut position is accurate; The utility model can be directed against 24 orifice plates, 96 orifice plates, 384 orifice plates different sizes is set respectively, and use range is wide.
Four, description of drawings
Fig. 1 is the structural representation of the utility model.
Among the figure: 1 body, 2 broach, 3 Tissue Culture Plates, 4 apertures.
Five, embodiment: the utility model is described further below in conjunction with accompanying drawing:
Fig. 1 is the structural representation of the utility model, and is as shown in the figure, a kind of cell migration analyzed in vitro experimental installation, and this device comprises body 1, and evenly distributed on the body 1 have many broach 2, and broach 2 is used for marking blank vestige at the aperture 4 of Tissue Culture Plate 3.For the utility model frame is contained on the Tissue Culture Plate 3, broach 2 both sides are respectively arranged with shoulder, be placed on 3 last times of Tissue Culture Plate when the utility model like this, the shoulder of broach 2 both sides can frame in the both sides of aperture 4, play the effect of fixed support.
During use, the utility model correspondence is placed on the Tissue Culture Plate 3, broach 2 is inserted in the aperture 4, and the shoulder frame of broach 2 both sides is in the both sides of aperture 4.In aperture 4, add cell culture fluid then, cultivate diel, treat cell attachment after, the utility model is taken out.At this moment, certain acellular clear area can be formed on the bottom of aperture 4, is positioned over microscopically again and observes, and how the cell of observing both sides moves in the clear area and get final product.

Claims (2)

1. cell migration analyzed in vitro experimental installation, it is characterized in that: this device comprises body (1), body (1) is gone up the evenly distributed many broach (2) that have.
2. a kind of cell migration analyzed in vitro experimental installation according to claim 1 is characterized in that: described broach (2) both sides have shoulder respectively.
CN 201120352894 2011-09-20 2011-09-20 Experiment device for in-vitro analysis on cell migration Expired - Fee Related CN202201903U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 201120352894 CN202201903U (en) 2011-09-20 2011-09-20 Experiment device for in-vitro analysis on cell migration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 201120352894 CN202201903U (en) 2011-09-20 2011-09-20 Experiment device for in-vitro analysis on cell migration

Publications (1)

Publication Number Publication Date
CN202201903U true CN202201903U (en) 2012-04-25

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN 201120352894 Expired - Fee Related CN202201903U (en) 2011-09-20 2011-09-20 Experiment device for in-vitro analysis on cell migration

Country Status (1)

Country Link
CN (1) CN202201903U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106520519A (en) * 2016-11-11 2017-03-22 四川大学华西医院 Ruler scratching device used for wound healing cell experiments

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106520519A (en) * 2016-11-11 2017-03-22 四川大学华西医院 Ruler scratching device used for wound healing cell experiments

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Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20120425

Termination date: 20140920

EXPY Termination of patent right or utility model