CN202195962U - Device for collecting fluid sample - Google Patents

Device for collecting fluid sample Download PDF

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Publication number
CN202195962U
CN202195962U CN2011202330510U CN201120233051U CN202195962U CN 202195962 U CN202195962 U CN 202195962U CN 2011202330510 U CN2011202330510 U CN 2011202330510U CN 201120233051 U CN201120233051 U CN 201120233051U CN 202195962 U CN202195962 U CN 202195962U
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China
Prior art keywords
sample
electrode
handle
light
collecting part
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CN2011202330510U
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Chinese (zh)
Inventor
勾利剑
胡海鹏
詹应安
赵福铨
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ABON Biopharm Hangzhou Co Ltd
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ABON Biopharm Hangzhou Co Ltd
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Priority to CN2011202330510U priority Critical patent/CN202195962U/en
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Abstract

The utility model relates to a device for collecting a fluid sample. The device comprises a collecting component for absorbing the fluid sample, a light-emitting element and a handle. The device is characterized in that the handle comprises a reflection structure which can reflect light. By adoption of the device provided by the utility model, the required fluid sample can be collected; enough samples can be tested and assayed; or the amount of samples is enough for a confirming test when the tests are finished. Moreover, the device for collecting the fluid sample can give a simple and explicit cue and a clear signal when collecting samples. The device is simple in operation, convenient and fast in production. Collecting efficiency is improved in the actual operation process.

Description

A kind of device that is used to collect fluid sample
Technical field
The utility model relates to a kind of collection that is used for fluid sample gathering-device field, particularly saliva sample, and the sample collection amount what are used to indicate.
Background technology
Common liquid sample is collected; Especially saliva collection device is such as the patent US 6,489 of Varian company; The sample collection device that proposes among the 172B1; Comprise that one is collected head and collects handle, put into testee's mouth, obtain and put into pick-up unit behind the sample again and carry out each item and detect collecting head.This gathering-device; Can collect sample simply fast; But there is certain defective:,, when receiving the external force extruding, be easy to generate saliva backflow owing to absorb the position deliquescing gradually of saliva because in collection process; Particularly when in gathering-device, being placed with some chemical indicators, pollute saliva sample to be detected because of the backflow of liquid.
Some gathering-device, for example US 7,114, and the fluid collection device of describing among the 403B2 can be used for collecting and storage even detection sample.Collect part and comprise a handle and a collection head, collect head and adopt sponge or other any materials that can absorb water.Put into measured's mouth with collecting head, certain hour takes out later on, puts into the sample storage parts of this device, through extruding sample solution is transferred to the reservoir part from collecting head.
Also have a kind of saliva sample to collect and pick-up unit, such as US 6,998; Propose among the 273B1; One is collected and be detected on to this device collection, in order to prevent that effectively sample is back to collecting zone in testing process, testing result and tester's health impacted; This device is provided with movably " fence " device between collecting zone and surveyed area; Be equivalent to a switch, can be controlled to collect and make sample and surveyed area reach circulation status again after finishing, carry out next step detection.
In another Chinese patent CN 201757716U, this device detects the sample collection amount through increasing electronic installation.When sample collection during to a certain amount of (such as being full of collecting part), electronic installation starts, and sends signal (like light or sound) and points out collecting amount to reach requirement.In the concrete mode, send prompting through light-emitting component.
In some test, the light that light-emitting component sends can not be received by the operator smoothly, such as, the light that light-emitting component sends is not in operator's visual line of sight, and the light that perhaps sends is fainter, is identified not too easily.
Summary of the invention
The utility model provides a gathering-device that can solve the fluid sample of more above-mentioned problems; This new device can make the brightness of light increase; And certain distance of light transmission and light luminance can not weakened, make the acceptant effect of operator thereby reach to light.
The device of the collection fluid sample that the utility model provides comprises the collecting part and the handle of absorption fluids sample, have on this handle can reflection ray reflective structure.In the preferred mode, also comprise in this gathering-device one can be luminous the element prompting collect what of fluid sample.
In another embodiment, this device also comprises electronic installation, and electronic installation comprises at least two electrodes and processor, and electrode contacts with collecting part; Preferably, light-emitting component is connected with electronic installation.
This reflective structure can make project this structural light carry out repeatedly reflection with/refraction; Make amount of light increase; Thereby the amount of light that gets into operator's eyes increases, and makes the operator observe the existence of light more easily and feels that light is very bright.
In order to make abundant reflection of light and/or refraction, a kind of of reflective structure is exactly to make the handle surfaces rustic, like this, can form a lot of tangent planes, and these tangent planes and not parallel or mutual intersection.After ray cast to a tangent plane, being reflected and/or reflecting reflection ray and/or the refracted ray that the back produces maybe or project other tangent planes, reflects once more and/or reflects.Finally, after the repeatedly reflection and/or refraction of Ray Of Light through a plurality of tangent planes, amount of light significantly increases, and is corresponding, and the amount of light that gets into operator's eyes also significantly increases, thereby is observed the existence of light easily by the operator.
In the concrete embodiment, reflective structure is for to be designed with groove on handle, and in the specific embodiment, this groove is corrugated or fan-shaped; In another embodiment, reflective structure is for to be designed with sags and crests on handle, and fold etc. make the coarse form of handle end; Among the embodiment of one optimization, fluted simultaneously and sags and crests design on handle.
In the embodiment, these reflective structures are positioned at an end of handle; Preferably, collecting part and light-emitting component are positioned at the other end of handle; Preferred, electronic installation and collecting part are positioned at same end, away from an end of reflective structure.
In some embodiments; The light source (light that the light-emitting component of electronic installation sends) that need will be positioned at handle one end (front end) is delivered to the other end (end) of handle; Perhaps to make whole handle all light can be arranged; Be that the observer need see that whole handle is luminous, therefore, can adopt the material of printing opacity to make handle or bar; In the more excellent mode, on handle or bar, be designed with cavity, the light that is positioned at an end (front end) can be sent to whole handle through cavity, perhaps is sent to the other end (end) of handle.
Be designed with these grooves and/or sags and crests in handle end, after the fold etc., can form a lot of tangent planes in handle end, these tangent planes make and to project being reflected and/or reflecting repeatedly of the terminal light of handle or bar by handle or bar front end.Promptly when light is injected into handle end; Light can be injected on these tangent planes; By reflection of these tangent planes and/or refraction, because of tangent plane is very many and not parallel, thereby the light of tangent plane reflection and/or refraction is injected into another or other a plurality of tangent plane again and by secondary reflection and/or refraction again.Like this, after reflection repeatedly and/or the refraction, the terminal amount of light of handle or bar increases; And increase from the amount of light that handle or bar end reflect; Increase thereby the amount of light that the person's of being observed who reflects eyes receive is also corresponding, therefore, more be prone to the person of being observed and receive.That is to say that the observer thinks that the terminal light luminance of handle or bar is strong.
Abundant and enough bright in order to guarantee handle or terminal light; The light transmission that the handle front end is injected reduces transmission loss as far as possible in the process of handle end; Promptly in transmission course, the generation refraction that light is tried one's best few even launch entirely, one preferred embodiment in; Can use light transmissive material to make handle, and cover the non-light transmissive material of one deck at its front end or middle-end; Another preferred embodiment in, can use non-light transmissive material to process the front end and the middle-end of handle, only use light transmissive material at the end of handle, more excellent, this handle design has the cavity of transmission ray.
In the specific embodiment, the front end of handle has cavity, and electronic installation is positioned at this cavity.This handle end that electronic installation is installed also is designed with scalloped recess and/or sags and crests design.After electronic installation sends signal (the element light emitting diode such as electronic installation emits beam); Promptly there is light source in the front end at handle; This light source is transferred to handle end through handle; Reflection and/or refraction through groove and/or sags and crests structure are finally received by the operator, and the operator just can point out the collecting amount that whether confirmatory sample reaches needs through the light of observing the handle end place.
In embodiment of the utility model, electronic installation also comprises power supply; This power supply makes has certain voltage on the electrode, thereby has certain potential difference (PD) between electrode.Under the situation of contacting with fluid not, not conducting between the electrode, being equivalent between two electrodes is an infinitely-great resistance.And at fluid sample with after electrode contacts; Owing to have potential difference (PD) between the electrode; Making electron ion in the fluid sample between electrode to electronegative potential (another electrode) electronics take place by noble potential (electrode) moves; Movement of electrons makes and forms little electric current between the electrode, forms interelectrode little current return.Along with increasing of sample size (also being the amount of electrons of sample), the electronics amount of movement also increases, and electric current increases gradually; Resistance between the electrode reduces gradually, and (this resistance can be reduced to 0 in theory, but in fact various sample has certain resistance when resistance is reduced to certain value; Therefore, the minimum value that resistance is reduced to can be the resistance value of sample), when promptly electric current reaches certain value; Electrode conduction forms current return, and electric current passes through.The loop that forms behind the electrode conduction can produce signal through processor processes, and this signal prompt electrode conduction has also promptly indicated fluid collection to a certain amount of state.Therefore, when collecting fluid sample, collecting part absorption fluids sample, when the sample in the collecting part reaches a certain amount of, this sample with contact with the collecting part electrode in contact equally, when sample size is able to make the amount of electrode conduction, electrode conduction.Electrode conduction reaches certain amount through sample in the signal prompt collecting part after send signal after the processor processes.
In the mode of optimizing, can and regulate what of sample collection amount through electronic installation control.In the concrete mode, the power supply in the electronic installation is transformable, and promptly the voltage that provides of power supply is transformable, regulates what of sample collection amount through transformable voltage.In the mode, how many voltage swing and sample collection amounts are inversely proportional to more specifically, and promptly when supply voltage reduced, the sample collection amount increased, and when voltage increased, the sample collection amount reduced.
In the mode of another optimization, electronic installation control and regulate what mode of sample collection amount for regulating the size of resistance value.In the mode, how many sizes of resistance value is directly proportional with the sample collection amount more specifically, and promptly when resistance value increased, the sample collection amount increased.Otherwise when resistance value reduced, the sample collection amount reduced.
In another mode of more optimizing, what of sample collection amount regulation voltage and resistance value control simultaneously.
In the embodiment, an adjustable resistance is connected with electrode and is made the fluid sample of collection more.The electrode sensitivity that series connection is regulated behind the resistance reduces, and stability increases, thereby has also increased the stability of sample collection.Be equivalent to a resistance between two electrodes, in the process of electrode contacting with fluid sample, the resistance between the electrode is along with the increase of fluid sample, and promptly electron ion diminishes after increasing gradually, when resistance drops to a certain degree, and electrode conduction.When after resistance is regulated in series connection on the electrode; Under the constant situation of given voltage, make the electric current of exporting behind the electrode conduction constant (being the minimal tour current value that processor sends signal demand), the resistance value between the electrode reduces before then regulating resistance than series connection accordingly; Thereby; Just needing more electron ion that the resistance value between the electrode is descended between the electrode, therefore, needing to collect the more fluid sample and obtain more electron ion.Like this, can avoid few sample contact electrode just to make the situation of electrode conduction, make the sensitivity of electrode reduce, thereby can increase the volume or the amount of collecting fluid sample.
Be appreciated that under the constant situation of resistance, can regulate what of the volume of collecting fluid sample or amount through the size of regulation voltage.For example, export a voltage V1 at the beginning, along with the electrode of fluid sample conducting electronic installation; Can increase the voltage of output this time; Be V2, V2 is greater than V1, and this time is under the constant situation of given resistance; Make the constant words of exporting behind the electrode conduction (being the minimal tour current value that processor sends signal demand) of electric current; Only conducting rapidly under the situation of the minimizing of the electron ion in fluid sample wants little or less when there are V1 in the volume of the fluid sample of collecting this time or amount relatively, can be controlled at fluid sample in the scope of small size like this.On the contrary, through regulation voltage also can be relative the volume of increase fluid sample.For example, export a voltage V1 at the beginning, along with the electrode of fluid sample conducting electronic installation; Can reduce the voltage of output this time; Be V2, V1 is greater than V2, and this time is under the constant situation of given resistance; Make the constant words of exporting behind the electrode conduction (being the minimal tour current value that processor sends signal demand) of electric current; Only conducting rapidly under the situation of the increase of the electron ion in fluid sample wants many when there are V1 in the volume of the fluid sample of collecting this time or amount relatively, like this can be the circulation sample of relative increase collection.
In the embodiment, collecting part comprises two ends.More excellent, electrode contacts with an end of collecting part; When collecting part is collected sample, the last end that contacts with electrode that arrives of fluid.
Even in collecting part in order to guarantee that collecting part is collected fluid sample; And guarantee to collect enough amounts, this electronic installation can be provided with a plurality of electrodes, and these electrodes are evenly distributed in the collecting part; In the specific embodiment, the electrode of electronic installation is 5.
In the concrete embodiment; In 5 electrodes; 3 electrode are connected with regulates what adjusting resistance of sample collection amount, and these regulate resistance at first makes the electrode sensitivity of connection reduce, what of size control fluid sample collecting amount that secondly can be through regulating resistance.The another one electrode connects power supply, and last electrode is as earth terminal.In the preferred mode, the electrode of earth terminal is metal-oxide-semiconductor control.
In the embodiment of an optimization, regulate resistance between 1-8Mohm.
In another embodiment, electronic installation can also comprise light-emitting component.This light-emitting component is connected with processor, and the sample collection amount what are used to point out.In the specific embodiment, light-emitting component is a light emitting diode.Behind electrode conduction, form current return, this electric current light emitting diode of flowing through after through processor processes, diode emits beam.So, when light emitting diode emits beam, promptly represent electrode conduction, also promptly indicated the amount that fluid sample is collected to be needed.
All element connected modes of electronic installation are various, can directly connect, also can connect indirectly, such as: connect through circuit, also can integrate or the like.One preferred embodiment in, all elements of electronic installation all integrate.
In some embodiments, the device of collecting sample can also comprise handle or the bar that is used to hold.More excellent, this handle or bar comprise three ends: front end, middle-end and end.
In another embodiment, this handle or bar are connected with collecting part, and more specifically, the front end of handle or bar links to each other with an end of collecting part.One more specifically in the embodiment, the handle or the bar that have electronic installation are connected with collecting part, and the electrode of electronic installation contacts with collecting part.
In the embodiment in the utility model, in order to guarantee the stability of sample collection amount, can be provided with fence at an end of collecting part; Preferably, this fence is positioned at an end that does not directly contact with sample; In another preferred mode, the internal diameter of fence is identical with the external diameter of collecting part.
In another embodiment, the fence height is not higher than the half the of collecting part height.
In the embodiment, this fence is positioned at collecting part and electronic installation junction; Preferably, handle also is connected with this fence; More specifically, this fence and handle are integral structure.
In the mode of an optimization, the electrode of electronic installation partly is positioned at collecting part, is positioned at the height and the height such as electrode that are positioned at collecting part of the fence on the collecting part.
In the utility model, in the handle of collecting part, testing element can be housed, testing element contacts with collecting part, and after collecting part was collected sample, sample entered into testing element and detects.In the embodiment, this testing element is a test-strips.
Beneficial effect
Can collect the fluid sample that needs through the device of the utility model, can collect enough samples and test or chemically examine; Perhaps sample size has enough detected and has confirmed to detect again.In addition, the enough prompting of the sample that such gathering-device carries out is simple, and clear and definite, the signal that provides is clear; The utility model is simple to operate, and it is convenient to produce, and has improved the efficient of collecting at actual mechanical process.
Description of drawings
Fig. 1 is that the embodiment device collecting part of the utility model is connected synoptic diagram with electronic installation
Fig. 2 is the basic circuit schematic diagram of the electronic installation of the utility model
Fig. 3 is another basic circuit schematic diagram of the utility model electronic installation
Fig. 4 is 5 electrode conduction circuit theory diagrams in the electronic installation of the utility model
Fig. 5 is the electrode conduction schematic diagram of regulating resistance that has of the utility model
Fig. 6 is a ground-electrode conducting schematic diagram in the electronic installation of the utility model
Fig. 7 is an embodiment device synoptic diagram of the utility model
Fig. 8 is the STRUCTURE DECOMPOSITION figure of Fig. 7 device
Fig. 9 is the part-structure exploded view (enlarged drawing) in Fig. 7 electronic installation
Figure 10 is the sectional view of Fig. 7 device
Figure 11 is another orientation synoptic diagram of device (along the handle end direction) of the utility model
Figure 12 is the light reflected refraction schematic diagram of handle special construction of the device of the utility model
Figure 13 is a branch of smooth reflected refraction synoptic diagram of the device handle end groove of the utility model
Figure 14 is the part enlarged drawing and signal detailed annotation figure of Figure 13
Description of symbols:
Gathering-device 700; Collecting part 100; Collecting part one end 101; The collecting part other end 102; Electronic installation 200; Electrode 201 (J1, J2, J3, J4, J5); Electrode one end 2011; The electrode other end 2012; Processor 202; Light-emitting component (light emitting diode) 203; Power supply 204; Regulate resistance R 1205; Handle 300; Handle front end 301, front end cavity 3011; Handle is affectedly bashful position (middle-end) 302; Handle end 303; Ripple type groove 3031; Concave point or salient point 3032; Adhesive board 400; Fence 500;
Embodiment
Further explanation done in the structure or these the employed technical terms that relate in the face of the utility model down.
Sample
The sample of any kind can both make an experiment with the device of the utility model, comprises body fluid (for example, urine and other body fluid, and clinical sample).Liquid sample possibly be derived from solid or semisolid sample, comprises excrement, biological tissue and food sample.These solids can be transformed into liquid sample through any suitable method with semisolid sample, for example in a kind of suitable liquid, mix, stamp broken; Macerate, hatch, dissolving or enzymolysis solid sample are (for example; Water, phosphate buffer or other damping fluid)." biological specimen " comprises the sample that is derived from animal alive, plant and food; Also comprise urine, saliva, blood and blood constituent, cerebrospinal fluid, vaginal swab; The culture of seminal fluid, ight soil, sweat, secretion, tissue, organ, tumour, tissue and organ; Condition medium cell culture and there is no matter be the people's or animal.These samples contain electrolyte, under certain voltage difference (potential difference (PD)) effect, can make the electric charge (electron ion) in the sample that electron transfer takes place.In addition, sample all has certain resistance value as a kind of material, different samples, and resistance value is also also inequality.What of needed fluid sample different samples can control or regulate through different resistance or voltage are set.
Analyte
Can analyze any analyte with the utility model.The example of the analyte of the enough the utility model stable detection of ability comprises (but not only comprising) human chorionic gonadotrophin (hCG); Lutropin (LH); Ovarian stimulation plain (FSH), hepatitis C virus (HCV), hepatitis B (HBV); Hepatitis B surface antigen, the medicine of AIDS virus and any abuse.Analyte can or liquefy at any liquid and detect in the sample, urine for example, saliva, saliva, blood, blood plasma, perhaps serum.The example of other analyte also has the acid of flesh ammonia acid anhydride, cholerythrin, nitrite, protein (nonspecific), blood; Leucocyte, blood sugar, heavy metal and toxin, bacterium composition (for example, special protein and the sugar of the bacterium of particular type; Colon bacillus 0157: H7 for example, staphylococcus aureus, salmonella, C.perfringens; Campylobacter, listeria monocytogenes, enteritis vibrios, perhaps cured shape bacillus).Any other analyte of suitable lateral flow assay form can detect with this device.Analyte can also be the material that material maybe can point out infection period that is infectious.Analyte can be medicine (like a drug abuse), hormone, albumen, nucleic acid molecules, pathogen." drug abuse " (DOA) is meant that the non-medical destination uses medicine (playing the paralysis nerve usually).Abuse these medicines and can cause body & mind to suffer damage, produce dependence, habit-forming and/or dead.The example of drug abuse comprises cocaine; Amphetamine (for example, black beauty, white amphetamine tablet, dextroamphetamine, dexie, Beans); Crystal methamphetamine (crank, meth, crystal, speed); Barbiturate is (like
Figure BSA00000530681000081
RochePharmaceuticals; Nutley, New Jersey); Sedative (paramedicines of promptly sleeping); Lysergic acid diethylamide (LSD); Suppressant (downers, goofballs, barbs, blue devils, yellow jackets, methaqualone); The anti-antidepressant of tricyclic antidepressants (TCA, i.e. imipramine, amitriptyline and doxepin); Hog (PCP); Tetrahydrocannabinol (THC, pot, dope, hash, weed, etc.); Opiate (being morphine, opium, codeine, heroin, the hydroxyl dihydrocodeinone).Use this test strip also can be used to belong to medical usage but the detection of overdose easily, like tricyclic antidepressant (imipramine or analog) and Paracetamol.
Testing element
Testing element can be selected the test strip of cross flow for use, and it can detect multiple analyte.Certainly, other suitable testing elements also can be used in the utility model.
Various testing elements can be combined in together and apply in the utility model.A kind of form is to detect test paper.The detection test paper that is used for the analyte (like drugs or show the metabolin of health) of analyzing samples can be a various forms, like immunoassays or chemico-analytic form.Detect the analytical model that test paper can adopt non-competing method or competition law.Detect test paper comprise one have sample application zone absorbent material, reagent area and test section.Add sample to sample application zone, flow to reagent area through capillarity.At reagent area, if there is analyte, sample combines with reagent.Sample continues to flow to detection zone then.Other reagent are fixed on detection zone like the molecule that combines with analyte specially property.Analyte in these reagent and the sample (if existence) reacts and analyte is combined in this district, perhaps combines with the some reagent of reagent area.The label existence that is used to show detection signal and reagent area or the mark zone that separates.
Detect
Detect the expression chemical examination or test a kind of material or whether material exists; Such as; But be not limited to this, the metabolin of chemical substance, organic compound, mineral compound, metabolism product, medicine or drug metabolite, organic organization or organic organization, nucleic acid, protein or polymkeric substance.In addition, detect the quantity of expression test substances or material.Furtherly, immune detection, chemical detection, enzyme detection etc. are also represented in chemical examination.
Collecting part 100
In some concrete embodiments, the device of collecting fluid sample comprises the collecting part 100 of absorption fluids sample.In a preferred scheme, collecting part 100 is mainly by forming through the absorbent material of chemisorption absorption and fluid storage sample.The material that constitutes fluid collection parts 100 can be selected from polyvinyl alcohol (PVA) (PVA), polyfoam, resin, sodium polyacrylate cross-linking agent; The AA-E acid copolymer, acrylonitrile polymerization is saponified, vinyl alcohol or sponge; Filter paper, glass, the combination of one or several of nonwoven fabrics or acetate fiber.Scheme that is more preferably be exactly the material that constitutes fluid collection parts 100 be polyethylene foamed alcohol.The shape of collecting part 100 can be right cylinder shape, rectangular parallelepiped, taper etc. any suitable shape.In a more concrete mode, like Fig. 7 and Fig. 8, collecting part 100 comprises two ends 101 and 102; One of them end 101 is used for contacting with fluid sample, and fluid sample is absorbed and gets in the collecting part 100.Perhaps, put into an end 101 of collecting part at certain position of gatherer and come the body fluid sample of absorptive tissue or organ secretion, saliva sample is collected in the oral cavity of for example putting into mammal or people to an end 101 of collecting part.Perhaps, can put into whole collecting part 100 in certain organ, for example put into mouth and collect saliva sample.Another end 102 of this collecting part is connected with electronic installation 200 or contacts with the subelement of electronic installation 200, and this contact or connection can be direct contacts, also can be through other conductor indirect contact or connection.In a concrete mode, the end of collecting part 102 is connected (as shown in Figure 1) through electrode 201 with processor 202 in the electronic installation 200.When collecting part 100 absorbs fluid sample; This fluid sample contacts with electrode 201 subsequently; Electrode 201 is switched on, and produces an electric current, after this electric current is processed device 202 receptions; Processor 202 lets electronic installation 200 send the enough identification signals of express liquid sample, and this signal can the person's of being collected identification or understanding.More concrete, the processor 202 in the suggestion device produces identification signal through control light-emitting component 203; According to these signals, the gatherer can know the state of collecting part 100, and perhaps according to these signals, the gatherer can take to continue to collect or stop to collect.
In another mode; Like Fig. 7-11; Collecting part 100 is bonded on the handle front end 301 through an adhesive sheet 400, and electronic installation 200 is positioned at cavity 3011, and electronic installation 200 comprises the electrode 201 that the conductor of two or more conductions forms; One end 2011 of each electrode directly contacts or directly is inserted in the collecting part 100 with the end 102 of collecting part 100; These electrodes 201 constitute a current return with power supply 204 and light emitting diode 203 (light-emitting component), and are as shown in Figure 2, after wherein any two electrodes 201 or a plurality of electrode 201 are simultaneously by the liquid conducting, form current return; Light emitting diode 203 sends light, and expression collecting part 100 is collected has enough fluids; On the contrary, when any two electrodes or a plurality of electrode can not be switched on lacking liquid simultaneously, can not form current return, light emitting diode 203 does not send light owing to there is not electric current, and the fluid that expression is collected is not enough.And after light emitting diode 203 emits beam, represent that promptly fluid sample reaches the amount that needs are collected, can stop to collect.These electrodes 201 also can be arranged on the processor 202, and all right integrated light-emitting diode 203, battery 204 or other parts constitute electronic installation 200 on processor 202; Collecting part 100 is bonded on the processor 202 through adhesive sheet 400, and electrode 201 contacts with collecting part 100.The circuit that electrode 201, light-emitting component 203 and battery 204 constitute can be as shown in Figure 2.Certainly, their annexation can also be other any mode, has below more specifically to describe.
When collecting liquid with this gathering-device 700, collected liquid sample and the moistening electrode that is connected with the end 201 when collecting part 100, after electrode 201 was by the liquid conducting, diode 203 sent light representations collecting part 100 and has collected enough samples; Opposite then enough samples are not also collected in expression.Further, the magnitude of voltage of battery (power supply) 204 or adjustment resistance value in the adjustment electronic installation 200 can be controlled what of collecting amount of fluid sample.
Collecting part 100 can soften after absorbing sample usually, and when especially when gathering sample, pressure being arranged, softening collecting part 100 is prone to be compressed, thereby influences the collecting amount of sample, causes what instability of sample collection amount.In the embodiment, be designed with fence 500 on the collecting part 100.Shown in figure 10.In the concrete mode, fence 500 designs are at an end of collecting part 100.More specifically, fence 500 is positioned at not a directly end of contacting with fluid sample, and promptly fence 500 is positioned at an end 102 of collecting part.This fence 500 is close together with collecting part 100, and promptly fence 500 internal diameters are identical with the external diameter of collecting part 100.Fence 500 has certain height, and the requirement for height design will guarantee the collecting amount of sample, and in the general embodiment, this fence 500 highly is no more than the half the of collecting part 100 height.
In the embodiment, the collecting part 100 that has fence 500 is connected with electronic installation 200; Concrete, an end 102 that has fence 500 contacts with the electrode 201 of electronic installation.Among the embodiment, an end 2011 of electrode gets into the end 102 that collecting part has fence 500.After being designed with fence 500; Electrode one end in contact in collecting part 100; Also can effectively stop displacement to cause electrode one end 2011 direct situation about contacting with the sampling position because of collecting part 100; Thereby avoided bad electrode conduction (be that the sample collection amount does not reach predetermined value, but directly touch the direct conducting of great amount of samples because of electrode 201).In the preferred embodiment, the height of this fence 500 is identical with the height of electrode 201 in collecting part 100.
In another specific embodiment, when collecting part 100 was connected with handle 300, fence 500 was adjoining with handle 300, and further, fence 500 can be connected with handle 300.In the preferred embodiment, fence 500 is an integral structure with handle 300.
Electronic installation 200
In some concrete embodiments, electronic installation 200 can comprise and collecting part 100 electrodes in contact 201 and processor 202, and the signal electron element 203 and power supply 204 that are connected with processor 202.These assemblies can connect through conductor or semiconductor, can make things convenient for the transmission of electronic signal between each assembly.In processor 200, can write the program software and the program circuit that write in advance and control processing and response each element signal.For example; When collecting fluid sample with collecting part 100, when collecting part 100 was collected a certain amount of fluid sample, the electrode 201 that is connected with collecting part 100 contacted with fluid; Electrode 201 conductings produce loop current; An electronic signal is accepted and sent to electric current by processor 202, and this electronic signal can let signal electron element 203, and for example signal lamp produces identification signal; For example light or sound, this light or auditory tone cues fluid sample are enough or reached predefined amount.In a preferred mode, be at least 2 with collecting part 100 electrodes in contact 201, in the starting stage, between two electrodes 201, apply a voltage; After two electrodes 201 are by fluid communication; Constituted current path; This current path is processed device 202 and receives electronic signal of back generation, and this electronic signal lets light-emitting component 203 send identification signal, and the expression fluid sample enough perhaps has been full of collecting part 100.Signal electron element 203 can pass through conductor, and for example electric wire is connected with processor 202; Electrode 201 also can be connected with processor 202 through conductor.In the embodiment of the utility model, electrode 201 directly integrates with processor 202.
The collected sample of collecting part that how much is meant of control that the utility model is alleged or adjusting sample collection amount satisfies the requirement that is provided with in advance; For example satisfy certain and chemically examine minimum or the highest needed volume or weight requirement, for example 0.5 milliliter, 0.7 milliliter, 1 milliliter, 5 milliliters or 1-10 milliliter.The sample size that sets can represent that whole collecting parts is full of fluid sample, can represent that also collecting part partly is full of by fluid sample.In the process of collecting sample, when sending the enough information of sample can realize light-emitting component prompting (like lumination of light emitting diode) through electrode conduction.Further,, also can make the conducting of electrode 201 accelerate or slow down through the size of regulation voltage (power supply) 204, thus the collecting amount of control and regulated fluid sample how much.Perhaps, regulate the size of resistance value, again or at electrode tip resistance in series R1 (205), both regulated the sensitivity of electrode, speed that also can the control electrode conducting, thereby what of the collecting amount of control fluid sample.Have again, when collecting different samples, can set what of collecting amount that different voltages with different and/or resistance value are controlled this sample according to different sample resistances.
Electronic installation can include only some electrodes 201, and power supply 204 (like button cell) of connecting with electrode and light-emitting component 203 (for example light emitting diode).After collecting part 100 was collected fluid sample, fluid sample contacted with the electrode 201 of electronic installation, and at this moment, electronic installation 200 is started working, and forms basic circuit as shown in Figure 2.In Fig. 2, during not conducting, being equivalent between two electrodes is an infinitely-great resistance between the electrode 201; And at fluid sample with after electrode 201 contacts; Because there is potential difference (PD) in the existence of supply voltage 204 between the electrode 201, this potential difference (PD) can make the electron ion in the fluid sample to electronegative potential (another electrode) electronics take place by noble potential (electrode) and move; Can reduce the resistance between the electrode gradually, so be equivalent to a transformable resistance R between the electrode 201; The voltage that power supply 204 provides is V; After the electrode in the electronic installation 200 201 touched fluid sample, the potential difference (PD) because of existing between the electrode 201 made the electronics of fluid sample move to low level from a high position; Finally make electrode 201 conductings to form current return, as shown in Figure 2; The electric current I circulation, also conducting of light emitting diode 203.Light emitting diode 203 after the conducting emits beam.After the operator receives light, promptly can stop to collect sample; Also promptly the sample size that needs is collected in expression.
At this moment, the basic functional principle of electronic installation 200 is formula (1):
I=V/R
V is the voltage that power supply 204 provides, and R is the resistance value that forms between two or per two electrodes 201.
When the I value reaches the conducting electric current of light-emitting component 203 (light emitting diode), then light-emitting component 203 (light emitting diode) conducting.
After two electrodes 201 were by fluid communication, this path had electric current I to pass through, and it is enough that light-emitting component 203 sends the amount of the liquid that light representations collects; If opposite light-emitting component 203 does not send light, then enough liquid samples have not also been collected in expression.
Further; Under the given constant situation of the signal conduction electric current I that needs reach; Also promptly in order to guarantee that light emitting diode 203 can be luminous, when power supply 204 voltages changed, then the resistance R between the electrode 201 also needed to change thereupon; According to formula (1), the resistance of electrode 201 and power supply 204 voltages are proportional.In the utility model, this relation can be used for controlling and regulate collecting part 100 and collects what of sample sizes.When power supply 204 voltage decreases, then the resistance between the electrode 201 also needs corresponding diminishing just can reach given current value I.Like this, need more sample electronics (electric charge) that electrode 201 resistance are reduced, therefore, between two or per two electrodes, need the more fluid sample to reach this requirement, promptly collecting part 100 needs to collect the more fluid samples.Otherwise when power supply 204 voltages increased, the resistance value of electrode 201 also should correspondingly increase, and then had less sample electronics can make electrode 201 conductings between two electrodes; Therefore after collecting less fluid sample, circuit can form the current value I that makes light-emitting component 203 (light emitting diode) conducting.So, how much being inversely proportional to of power supply 204 voltages and sample collection amount.
In another preferred embodiment, what of sample collection amount electronic installation 200 also can control through regulating resistance.The mode of regulating resistance is not limited on electrode, increase an adjustable resistance, as long as the resistance value of entire circuit is changed.Among one embodiment, the function that can realize regulating resistance through the resistance value of regulating light-emitting component.
In another preferred embodiment, resistance in series R1 (205) on the electrode 201, its fundamental diagram is as shown in Figure 3.At this moment, the principle of work of electronic installation 200 is formula (2):
I=V/(R+R1)
V is a supply voltage, and R is the resistance value that forms between two or per two electrodes, and R1 is for regulating the resistance of resistance R 1 (205).
When the electric current I value reaches the conducting electric current of light-emitting component 203 (light emitting diode), then light-emitting component 203 (light emitting diode) conducting.
In the time will reaching the electric current I of light-emitting component 203 conductings (even the luminous minimum current value of light-emitting component), under the constant situation of power supply 204 voltages, i.e. V; I is fixedly the time; According to formula (2), when regulating resistance R 1 (205) increase, electrode 201 resistance R just need reduce accordingly; Otherwise when adjusting resistance R 1 (205) reduces, electrode 201 resistance R will increase.Therefore, can control what of sample collection amount through adjusting resistance R 1 value that adjusting increases newly.After increasing adjusting resistance R 1 (205), need more sample electronics (electric charge) that electrode resistance R is reduced, this sample electronics is increased thereby need to collect the more fluid sample.Opposite, according to formula (2), when adjusting resistance R 1 (205) reduced, electrode resistance R then needed to increase, and therefore, collects less fluid sample, can make electrode 205 conductings.Therefore, regulate the resistance of resistance R 1 (205) and how much being directly proportional of sample collection amount.
Generally; Conductor electrode 201 sensitivity are higher, when touching fluid sample, and very easily conducting of electrode 201; After particularly collecting part 100 receives the pressure of part from sampling place when collecting sample (when collecting saliva sample; Collecting part pressure can be given in the oral cavity), electrode 201 conducting after collecting certain sample, thus light emitting diode 203 lamps are bright.But sometimes after collecting part 100 leaves sampling place; Pressure disappears; When concentrating near the electrode 201 samples originally and possibly have other positions, particularly collecting part 100 that part is distributed to collecting part 100 and be not full of by sample, this situation takes place more easily.At this moment, electrode 201 might cause reflective diode 203 to extinguish because of the not conducting again of sample size deficiency.The sample size that can cause like this collecting how much becomes uncertain or the sample collection amount does not reach predetermined requirement.Therefore, regulate resistance R 1 (205) and also have another effect, even the sensitivity of electrode 201 is lowered.Owing to form infinitely-great resistance R between the electrode 201; Behind the contacting with fluid sample, the resistance R that electrode is 203 constantly reduces, and electrode 201 is switched on; After the adjusting resistance R 1 (205) of the certain resistance of series connection; The circuit total resistance value increases, and electrode 201 is switched on not too easily, and electrode 201 stability increase.In the specific embodiment, this resistance of regulating resistance R 1 (205) more than or equal to 1Mohm after, can effectively increase the stability of electrode 201.
Following table 1 for the resistance of the adjusting resistance R 1 (205) that increases under different resistances, when gathering-device 700 is collected samples, light emitting diode 203 luminous and the data plot that extinguishes.(every group is adopted 5 samples)
Table 1:
R1 resistance (ohm) 100K 200K 500K 800K 1M 2M 6.2M 8M
The bright unstable ratio of lamp 5/5 3/5 3/5 1/5 0/5 0/5 0/5 0/5
Certainly; Resistance R 1 (205) value is big during to certain value when regulating, when sample is full of collecting part 100, promptly during R value infinitely small (R at time be the resistance value of sample); Circuit also can not form current return too greatly because of the R1 value, thereby light emitting diode 203 can be not luminous.Like this, this gathering-device 700 just can't be realized it and collect the function of prompting.Therefore, when connecting, adjusting resistance R 1 (205) had better not be infinity when regulating resistance R 1 and R value (R at time be the resistance value of sample).
In the mode of an optimization, the scope of therefore regulating the resistance of resistance R 1 (205) is 1Mohm---8Mohm.
The utility model device can be used to collect multiple sample, and usually, the resistance value of various samples is not quite similar, and promptly the resistance R value during conducting has nothing in common with each other between electrode.Among the preferred embodiment, regulation voltage is controlled and the collecting amount of regulating different samples with resistance simultaneously.For example, when collecting saliva sample,, preestablish a supply voltage, control the saliva collection amount through regulating resistance according to the resistance value of saliva; And when the collection body fluid samples,, reset another supply voltage value then according to the resistance value of body fluid, again through regulating the collecting amount that resistance value is regulated body fluid.
Handle 300
In other concrete embodiments, Fig. 7 and shown in Figure 8, collecting part 100 can be connected with a handle 300.The cavity design can be arranged in the handle 300, comprise the cavity 3011 of an end opening.Handle 300 can connect collecting part 100 and is fixed on the handle 300 through adhesive board 400.Fixing mode has a lot; For example can be; Can be provided with hasp on the adhesive board 400 sample collection parts 100 are fixed on an end of handle 300, also can one end 102 of collecting part 100 be bonded on the adhesive board 400, such as adopting glue through being stained with sticking form.In a preferred mode, electronic installation 200 is positioned at 3011 li of the cavitys of handle 300.More specifically, the openings of sizes of processor 202 and cavity 3011 is suitable, can let whole electronic installation 200 be positioned at cavity 3011.An end 2011 that is positioned at the electrode 201 of cavity passes adhesive board 400 and contacts with an end 102 of collecting part 100.Simultaneously, electronic installation 200 comprises a signal electron element 203, and identification signal is sent through element 203.This light-emitting component 203, for example light emitting diode can be integrated on the processor 202.When collecting fluid sample; Put into collection body fluid samples in people or mammiferous certain organ to an end 101 or the whole collecting part 100 of collecting part; Collecting part 100 contact liqs are also slowly filled by liquid, when the fluid sample of 100 li of collecting parts arrives the end 102 of collecting part, are positioned at the two or more electrodes that are positioned at collecting part end 102 equally 201 that separate of fluid sample conducting of collecting part 100; The electrode of this conducting forms current return; Let processor 202 produce an electronic signal, this electronic signal lets light-emitting component 203 send identification signal, such as; Diode emits beam, and points out the fluid sample of this collecting part 100 to collect the amount that needs.
In another optional mode, gathering-device also comprises the testing element of analyte in the test sample book.In a concrete mode, testing element is positioned at a handle 300.Handle 300 is connected with collecting part 100, and the fluid of collecting part 100 can be flow on the testing element.Also can pass through other water conservancy diversion material, for example filter paper etc., overlap joint indirectly.Let the fluid from collecting part 100 flow on the testing element through the water conservancy diversion material.In another concrete mode, electronic installation 200 also is positioned at housing, and the electrode 201 of electronic installation contacts with collecting part 100.When in use, if collecting part 100 is collected enough samples are arranged, electronic installation 200 sends identification signal through light-emitting component 203; The expression sample is enough; Can stop to collect, then, the fluid sample that is collected on the collecting part 100 passes through the sample region of acceptance successively; Marked region, surveyed area; Pass through the testing result of test zone on the read test element at last.
Handle 300 can also comprise a passage or cavity; One end of this passage or cavity communicates with cavity 3011; The other end of this passage is with handle end 303 or be affectedly bashful position 302 and communicate; When handle front end 301 had light source to exist, light can pass passage and shine handle end 303 or shine and be affectedly bashful position 302, and the person that collects the sample like this can directly see light and stop to collect.Certainly; In a selectable mode; Handle 300, cavity or one or more parts of being affectedly bashful in the position 302 (middle-end) are formed for the material that can be seen through by light, for example transparent plastic, glass etc., and being arranged in the light that the light-emitting component 203 in chamber sends can be observed.
In another preferred mode, handle end 303 is designed with special reflective or printing opacity design, is scalloped recess 3031 or on handle end, is designed with sags and crests 3032 like end.Some sample is when collecting; Because the part restriction, need stronger light occur in handle end 303 could be received by the operator, such as: when collecting the human body saliva sample; The operator holds the handle of gathering-device 700 and is affectedly bashful portion 302; Collecting part 100 is put into mouth collect saliva sample, at this moment, operator's eyes often are merely able to see the handle end 303 of gathering-device 700.
Special construction 3031, the 3032 main effects of handle 300 ends 303 are that the light source that is mapped to end 303 can repeatedly be launched and/or refraction, finally make more rays received by operator's eyes.Its main action principle is shown in figure 12, and a is the handle material, and b is the outside air layer, and c is the interface of handle and air, and d is the normal vertical with interface c.The density of handle material is greater than the density of air; When light A1 is delivered to handle end 303 and arrives handle and during the e point of the interface c of air, according to reflection of light and refraction law, emission and refraction take place on the interface c of light A1 in handle from handle front end 301; The light A2 that reflects is still in handle a; The light A3 of refraction then gets among the air b, and incident angle α equals reflection angle β, and refraction angle γ is greater than incident angle α.Light A2 in handle material a possibly be injected into other interface places of handle material a, and reflection and/or refraction take place once more; The light A3 that gets into air layer b then possibly directive operator eyes direction received by the operator, also possibly be injected into other directions of air layer b, also possibly be injected into to reflect once more on other interfaces of air b and handle a and/or reflect.Reflection and/or refraction through light A2 and A3 can derive more rays.And the like; The most light that are delivered to handle end 303 from handle front end 301 all can be the same with light A1, and the special construction 3031,3032 through handle end reflects and reflects; The light of reflection and refraction is reflected and reflects, and derives more rays.Thereby; Just having more rays is refracted in the ambient air through handle end 303; And have more rays to be reflected at the air place of handle end 303, final, light significantly increases in handle end 303 ambient airs; Accordingly, these light quantity of being injected into operator's eyes also can increase.Therefore, the light of the observed handle end 303 of operator can brighten.
In other preferred modes; For the light source that makes handle front end 301 can effectively be transferred to handle rear end 303; Be designed with cavity in the handle 300 again; The light source of front end 301 can directly be transferred to rear end 303 through cavity, the loss of avoiding light in through the transmission of handle material, to reflect away.More excellent, the front end 301 of handle uses lighttight material to process with middle-end 302, has only terminal 303 to use light transmissive material to process, and so also can effectively reduce light transmission to terminal loss.
A practical implementation device with regard to the utility model carries out detailed structure explanation and method of application explanation below.
In the specific embodiment of the utility model, like Fig. 1 and shown in Figure 7, this gathering-device 700 comprises the collecting part 100 and electronic installation 200 of absorption fluids sample.Electronic installation 200 comprises electrode 201, processor 202 and light emitting diode 203, and further, electronic installation 200 also comprises power supply (battery) 204, and is as shown in Figure 9.Wherein, collecting part 100 is connected with electronic installation 200.More specifically, an end 102 of collecting part and electronic installation 200 an assembly--an end 2011 of-electrode 201 is connected.The other end 2012 of electrode is connected with processor 202.Light emitting diode 203 is connected on the processor 202.
When the use of reality operation, conducting has certain contingency between two electrodes 201, when collecting, only accumulates in two electrode (this moment electrode may conducting) such as, sample, and other collecting part places do not collect.Like this, can cause the collecting amount of sample and original collecting amount of setting to have deviation.Therefore, more stable in order to make testing result, can increase the quantity of electrode, and a plurality of electrodes 201 are evenly distributed in the end 102 of collecting part 100.In a preferred specific embodiment, the equally distributed electrode 201 in the electronic installation 200 be 5 (J1, J2, J3, J4, J5).In the preferred mode, an electrode J5 in 5 electrodes is as power end, and another electrode J2 is an earth terminal, and its excess-three electrode J1, J3, J4 all are in series with and regulate resistance R 1 (205), and be as shown in Figure 4.Be connected with three electrode J1 that regulate resistance R 1 (205), J3, J5 input end A, B, C through adopt with gate logic (A*B*C=Y promptly works as A, B, when C3 input end all had high level, output terminal Y also exported high level; If A, B, C end have 0, and when 1 or 2 ends had high level, output terminal Y is did not have high level output) the processor 202 output signal Y of principle, output terminal Y is connected with light-emitting component 203.As three electrode J1, J3 during the equal conducting of J4 input end, be connected with the also conducting of output terminal of light-emitting component 203, thereby cue is sent in light-emitting component 203 conductings.Three electrode J1 wherein, J3, each the electrode fundamental diagram among the J4 is as shown in Figure 5, and its principle of work is formula (3):
Vcc/(R+R1)=Vt/R1
Vcc is the supply voltage that J5 provides, and Vt is the cut-in voltage of processor 202, and R is the electrode resistance, and R1 is for regulating resistance value.When this formula (3) is set up, when promptly reaching the electric current of electrode conduction, this electrode J1; J3; The J4 conducting, according to the principle of gate logic (A*B*C=Y), also conducting of output terminal Y; Thereby make light-emitting component 203 conductings, signal (LED light lamp is bright) the prompting sample collection amount of sending through light-emitting component has reached predetermined value.
Wherein, the cut-in voltage Vt of processor 202 is relevant with the product type that begins to select, in case selected model is fixed value.Equally, when reducing power source voltage Vcc, resistance R need reduce, the then corresponding increase of sample collection amount, on the contrary Vcc increases, and resistance R increases, and the sample size of collection reduces.And the relation of regulating resistance R 1 and R also is corresponding, when R1 increases, needs R to reduce, and the sample collection amount increases, and perhaps, R1 reduces, and then R increases, and the sample collection amount increases and decreases few.
More specifically, the electrode J2 of earth terminal adopts the principle control of using metal-oxide-semiconductor, and is shown in Figure 6.I.e. when supply voltage is 0 (when gathering-device did not use, power supply was in off-state), ground-electrode J2 input end is a high-impedance state, is equivalent to break off, promptly processor 202 is in closed condition.Like this; Can guarantee that the utility model device is not when collecting fluid sample; Electronic installation 200 is in off-state, and both energy efficient guaranteed the accuracy (can not make collecting amount not reach predetermined collecting amount because of the loss of power supply) of when this device 700 is collected sample, collecting again.In concrete embodiment, the resistance of the adjusting resistance R 1 (205) of connecting with three electrodes is can 1-20Mohm.One more specifically in the embodiment, this resistance is 1-8Mohm.
Among the embodiment, like Fig. 7 and shown in Figure 8, also comprise a handle 300 more specifically, this handle 300 is connected with an end 102 of collecting part 100.This handle 300 has the front end 301 that links to each other with collecting part 100, is suitable for the portion of being affectedly bashful (middle-end) 302 and handle end 303 that hand is taken.In the preferred mode, the front end 301 of handle has cavity 3011, and is preferred, and all elements of electronic installation 200 integrate, and are positioned at handle cavity 3011.
Shown in Figure 8, when electronic installation 200 is positioned at the cavity 3011 of handle 300 front ends, and an end 2011 of electrode 201 is when being positioned at an end 102 of collecting part 100; The other end 101 of collecting part 100 contact and collects sample with the sampling position, collect a certain amount of sample after, fluid sample edge 101 ends in collecting part 100 are mobile to 102 ends; Finally contact with electrode one end 2011 that is positioned at 102 sections; Along with the continuous increase of sample, the sample size at an end 2011 places of 5 electrodes also increases gradually, and is final; Enough sample sizes make electrode 201 conductings; The high level that electrode 201 conductings produce makes processor 202 output high level, thereby makes light-emitting component 203 conductings, i.e. lumination of light emitting diode.
Light emitting diode 203 is positioned at the cavity 3011 of handle front end 301; For the light that guarantees to send can be received by the operator, handle 300 materials that comprise electronic installation can be light-transmitting materials, like transparent plastic; What use in glass or the like, this instance is transparent ABS material.When collecting part 100 is collected the sample size that needs; Electrode 201 conductings, electronic installation 200 work emit beam light emitting diode 203, and this light is positioned at the cavity 3011 of handle front end; Because of handle is a light-transmitting materials, then the light that sends of this diode 203 can be transferred to whole handle 300.The operator just can see that whole handle 300 is illuminated by light, thereby stops to collect sample.But collecting the part sample; During such as saliva sample; What normally the operator held handle is affectedly bashful position 302, mouthful carries out the collection of saliva sample with what collecting part 100 was put into the operator, like this; The operator just is difficult to observe the front end 301 and the middle-end (being affectedly bashful portion) 302 of handle, can only remind the operator whether sample collection is enough through the light of handle end 303.And behind the whole handle of light transmission that the light emitting diode 203 of handle front end 301 sends; Handle end 303 is because of apart from handle front end 301 farthest; Light constantly reflects in transmission course; The light that arrives end 303 has quantitatively still all reduced much in the brightness, so, the too weak phenomenon of not knowing or not observing of observing of light may take place.In the present embodiment, increase some groove design 3031 and sags and crests design 3032, make light quilt reflection and the refraction repeatedly that shines handle end 303, increase the quantity and the intensity of light, make the operator more be prone to observe in handle end 303.Shown in figure 11, be designed with scalloped recess 3031 and a large amount of sags and crests 3032 in handle end 303.When light arrival handle end 303, shown in figure 13, light is in interface place generation reflection and the refraction of groove 3031 with air, and light reflected arrives the interface place of another groove 3031 and air once more, takes place once more to reflect and refraction.So circulate repeatedly, amount of light increases, and being refracted to airborne amount of light increases, thereby the amount of light that gets in operator's eye also increases.After the light emitting diode 203 of the cavity that is positioned at handle front end 301 3011 emitted beam, the operator more was prone to observe light in handle end 303.Figure 14 is the concrete reflected refraction synoptic diagram of the Ray Of Light of this instance; The scalloped recess 3031 that the light D that sends from light emitting diode 203 is transferred to handle end 303 is during with the interface g of air; Emission and refraction law according to light; Reflection and refraction take place, and form reflection ray E and refracted ray F, this refracted ray F may be injected into the operator the eyes observation scope and seen by the operator; Reflection ray E projects the interface h place of another groove 3031 and air in handle end, and reflection and refraction take place once more, forms another reflection ray G and another refracted ray H.Reflection ray G may project handle end 303 another positions, and reflection and/or refraction take place once more.Refracted ray H then shines the interface k place of air and groove, and reflection and/or refraction also can take place again.
Among another embodiment,, can be designed with fence 500 on the collecting part 100 in handle 300 and collecting part 100 junctions.Like Fig. 7 and shown in Figure 10, this fence 500 is positioned at an end 102 places of collecting part, and fence one end is connected with the front end 301 of handle 300.More specifically, fence 500 can with handle 300 one-shot formings.Electronic installation 200 is positioned at the front end cavity 3011 of the handle 300 that has fence 500, and an end 2011 of an element of electronic installation 200---electrode 201 contacts with an end 102 of collecting part 100.In the present embodiment; One end 2011 of electrode is positioned at collecting part one end 102; For the sample that guarantees to collect can not soak other electronic components of electronic installation 200; The adhesive sheet 400 that between electronic installation 200 and collecting part 100, has a waterproof material to process, an end 2011 of electrode 201 passes adhesive sheet 400 and contacts with collecting part 100.When collecting part 100 with after handle 300 is connected, an end 102 of collecting part is positioned at the inboard of fence 500.The interior diameter of fence 500 can be identical with the diameter of collecting part 100.The height of fence 500 is not limit, and is high more in principle good more, but preferably is no more than half height of collecting part 100.In the specific embodiment, the height of this fence 500 is identical with the height that electrode 201 is positioned at collecting part 100.
Because of fence 500 is set up the place, the place that links to each other with electrode 201 of collecting part 100 just.After setting up fence 500, can reduce or avoid sample just to contact, prolong the time that electrode 201 touches sample, also make in the collecting part 100 and can be full of sample more fully, avoid contingency with electrode 201 at the collection initial stage.In addition, fence 500 is set after, the part that collecting part 100 has fence also not too can move at sampling point, thereby can not cause electrode 201 directly contact sampling points or sample and mislead.
Usually, general sample collection parts 100 can have the sample size above 1ml when collecting full sample, carry out smoothly and the sample that is used to detect can guarantee to detect between 0.5ml to 1ml.Greater than the sample size of 1ml, can guarantee that then sample can also have the residue sample to be used for the secondary affirmation after to be detected.
Form 2 has been enumerated the utility model device and fence has not been set and is provided with the just data of the sample collection amount of two kinds of fences.
(gathering sample size is 32 parts)
Table 2:
Figure BSA00000530681000181
Can find out that through table 2 in this gathering-device 700, set up fence 500 front and back and fence from low to high, the sample collection amount obviously descends less than the ratio of 0.5ml, like this, can guarantee that the sample size that this gathering-device 700 is collected can detect.

Claims (10)

1. a device that is used to collect fluid sample comprises the collecting part that is used for the absorption fluids sample, and light-emitting component and handle is characterized in that, described handle comprise can reflection ray reflective structure.
2. device as claimed in claim 1 is characterized in that, said reflective structure that can reflection ray is positioned at handle one end.
3. device as claimed in claim 2 is characterized in that collecting part and light-emitting component are connected the other end of handle.
4. device as claimed in claim 3 is characterized in that, described handle is all or part of to be light-transmitting materials.
5. device as claimed in claim 4 is characterized in that, the cavity that described bar or handle inside have hollow.
6. device as claimed in claim 5 is characterized in that, described reflective structure is a scalloped recess.
7. device as claimed in claim 5 is characterized in that, described reflective structure is concave point or salient point.
8. like any described device of claim 1-7, it is characterized in that said device also comprises electronic installation, electronic installation comprises at least two electrodes and processor, and electrode contacts with collecting part, and light-emitting component is connected with electronic installation.
9. device as claimed in claim 8 is characterized in that, said electronic installation is positioned at the maybe cavity of this end of a end that collecting part is connected with handle.
10. device as claimed in claim 9 is characterized in that, the electrode of said electronic installation is 5; One of them electrode is a power end; Another electrode is an earth terminal; All the other 3 electrode are connected with adjustable resistance.
CN2011202330510U 2011-06-30 2011-06-30 Device for collecting fluid sample Expired - Lifetime CN202195962U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109682873A (en) * 2019-01-25 2019-04-26 京东方科技集团股份有限公司 A kind of saliva detection device and system

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109682873A (en) * 2019-01-25 2019-04-26 京东方科技集团股份有限公司 A kind of saliva detection device and system

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