CN202159053U - Disintegration time tester - Google Patents

Disintegration time tester Download PDF

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Publication number
CN202159053U
CN202159053U CN201120256829XU CN201120256829U CN202159053U CN 202159053 U CN202159053 U CN 202159053U CN 201120256829X U CN201120256829X U CN 201120256829XU CN 201120256829 U CN201120256829 U CN 201120256829U CN 202159053 U CN202159053 U CN 202159053U
Authority
CN
China
Prior art keywords
water bath
disintegration
control box
cup
medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201120256829XU
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Chinese (zh)
Inventor
陈佩英
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BEIJING YINGMAO PHARMACEUTICAL Co Ltd
Original Assignee
BEIJING YINGMAO PHARMACEUTICAL Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BEIJING YINGMAO PHARMACEUTICAL Co Ltd filed Critical BEIJING YINGMAO PHARMACEUTICAL Co Ltd
Priority to CN201120256829XU priority Critical patent/CN202159053U/en
Application granted granted Critical
Publication of CN202159053U publication Critical patent/CN202159053U/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

The utility model discloses a disintegration time tester which comprises a control box and a water bath fixed at the top of the control box. A circular hole is formed at the top of the water bath; a disintegration cup is immersed into the water bath through the circular hole; a drug hanging basket immersed into the disintegration cup is fixed on a transmission bracket connected with the control box; and a heater, a thermometer and a water pump are respectively connected with the control box and immersed into the water bath. The disintegration time tester heats the disintegration cup through the water bath; the disintegration cup dissolves drugs in the drug hanging basket within constant temperature range; and the disintegration time tester accurately and effectively measures the time for dissolving the drugs in digestive canal of a human body through simulation, and provides strong support for medical pharmacy.

Description

Disintegration time limited appearance
Technical field
The utility model belongs to medical dissolution time sensing equipment field, relates in particular to a kind of disintegration time limited of appearance.
Background technology
As far back as decades ago just the someone point out, medicine in vivo infiltration rate usually by the dissolving speed and determine that the medicine in the solid pharmaceutical preparation is before being absorbed; The process that must transfer solution then to through disintegration and dissolving, if medicine is difficult for from preparation, discharging or the dissolution velocity of medicine is very slow, then the infiltration rate of said preparation Chinese traditional medicine or degree just might have problems; On the other hand, some pharmacological action is violent, and safety index is little; The medicine dissolution rate is too fast rapidly if absorb, and possibly produce tangible bad reaction, and the time of keeping drug effect also will shorten; In this case, the dissolution rate of preparation of traditional Chinese medicine should give control.So measuring rate of dissolution and the dissolution time of oral medicinal in human body just becomes the important ring of medical science pharmacy.
Summary of the invention
In order to measure Peroral solid dosage form medicines such as tablet, capsule dissolution velocity in stomach especially in human body, the utility model provides a kind of appearance disintegration time limited that is used to measure dissolution time.
The technical scheme of the utility model does; Disintegration time limited appearance; The water bath, the water bath top that comprise control box, are fixed on the control box top have circular hole, and the disintegration cup immerses water bath through circular hole, immerse on the transmission bracket that the medicine hanging basket is fixed on control box connects together of disintegration cup; Well heater, thermometer and water pump are connected with control box respectively and immerse in the water bath.This step adds water to earlier waterline in water bath; The disintegration cup immerses water bath through the circular hole at water bath top; In the disintegration cup, be added with the liquid of anthropomorphic dummy's body fluid again; The control box control heater is heated to water between 36.5 degrees centigrade to 37.5 degrees centigrade afterwards, immerses the disintegration cup to the medicine of needs dissolving through the medicine hanging basket, and medicine begins disintegration.Thermometer is measured the temperature of water bath water in real time and the result is issued control box, and between 36.5-37.5 degree centigrade, water pump flows the water cycle in the water bath to control box, and the disintegration cup is heated evenly with temperature maintenance.
LCD, power switch and the adjusting button of demonstration time and temperature are installed on the temperature control box panel, and power switch is connected with the adjusting button with LCD respectively.In this step, the temperature of water bath is shown on the LCD in real time, when test determination, is convenient to the observed temperature parameter, regulates button and can set the medicine disintegration time, and the disintegration experiment can directedly regularly be carried out.
Description of drawings
Fig. 1 is the structural representation of the utility model;
Fig. 2 is the structure schematic side view of the utility model;
Wherein, 1, control box, 11, LCD, 12, power switch, 13, regulate button, 2, water bath, 3, the disintegration cup, 4, the medicine hanging basket, 5, transmission bracket, 51, cantilever, 6, well heater, 7, thermometer, 8, water pump.
Embodiment
Below in conjunction with accompanying drawing the utility model is further specified.
With reference to Fig. 1, a kind of embodiment of the utility model.Disintegration time limited appearance, the water bath 2, the water bath top that comprise control box 1, are fixed on the control box top have circular hole, disintegration cup 3 immerses water bath through circular hole, immerses on the transmission bracket that medicine hanging basket 4 is fixed on control box connects together of disintegration cup 5; Well heater 6, thermometer 7 and water pump 8 are connected with control box respectively and immerse in the water bath.LCD 11, the power switch 12 of demonstration time and temperature is installed on the temperature control box panel and regulates button 13, power switch is connected with the adjusting button with LCD respectively.When using the utility model, in water bath, add entry, the disintegration cup immerses in the water of water bath.The disintegration cup is the beaker shape, holds the simulated body fluid of simulated body fluid in the beaker, and simulated body fluid is by the water of water bath heating but do not exchange with water, fixes with transmission bracket behind the medicine hanging basket loading medicine and immerses in the disintegration cup.The medicine hanging basket is the test tube shape, and the bottom has the aperture that can come in and go out for liquid, supplies simulated body fluid that medicine is dissolved.Thermometer is measured the temperature of water in the water bath in real time and the result is passed to control box, and at 36.5-37.5 degree centigrade, water pump flows the water cycle in the water bath to the control box control heater with temperature maintenance in the water bath, and it is more even to be heated.
The LCD of control box panel, power switch and adjusting button make the operation of control box more simple; The duty of power switch control appearance disintegration time limited; Medicine dissolution time and temperature of reaction that liquid crystal display displays is present; Regulate button and can set the dissolution time and the temperature of medicine, be convenient to observe at times the medicine response situation.
With reference to Fig. 2, the another kind of embodiment of the utility model.When using the utility model that medicine is carried out disintegration time mensuration, the cantilever 51 of control box control transmission bracket drives the medicine hanging basket and in the disintegration cup, moves up and down, the dissolving situation of simulation medicine when organ is wriggled.
The above; Preferable case study on implementation for the utility model; Be not that the utility model is done any restriction; Everyly any simple modification that above embodiment did, change and equivalent structure are changed, all still belong in the protection domain of the utility model technical scheme according to the utility model technical spirit.

Claims (2)

  1. Disintegration time limited appearance; Comprise control box (1), be fixed on the water bath (2) at control box top, it is characterized in that the water bath top has circular hole; Disintegration cup (3) immerses water bath through circular hole, and the medicine hanging basket (4) that immerses the disintegration cup is fixed on the transmission bracket (5) that connects together with control box; Well heater (6), thermometer (7) and water pump (8) are connected with control box respectively and immerse in the water bath.
  2. 2. disintegration time limited according to claim 1 appearance; It is characterized in that; LCD (11), the power switch (12) of demonstration time and temperature is installed on the panel of temperature control box and regulates button (13), power switch is connected with the adjusting button with LCD respectively.
CN201120256829XU 2011-07-20 2011-07-20 Disintegration time tester Expired - Fee Related CN202159053U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201120256829XU CN202159053U (en) 2011-07-20 2011-07-20 Disintegration time tester

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201120256829XU CN202159053U (en) 2011-07-20 2011-07-20 Disintegration time tester

Publications (1)

Publication Number Publication Date
CN202159053U true CN202159053U (en) 2012-03-07

Family

ID=45766685

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201120256829XU Expired - Fee Related CN202159053U (en) 2011-07-20 2011-07-20 Disintegration time tester

Country Status (1)

Country Link
CN (1) CN202159053U (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104422755A (en) * 2013-09-09 2015-03-18 北京量子高科制药科技有限公司 Method for detecting disintegration time of quick disintegration preparation
CN104422756A (en) * 2013-09-09 2015-03-18 北京量子高科制药科技有限公司 Disintegration time limit determination device for rapid disintegration preparation
CN111707791A (en) * 2020-06-28 2020-09-25 青海省药品检验检测院 Self-monitoring intelligent disintegration tester

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104422755A (en) * 2013-09-09 2015-03-18 北京量子高科制药科技有限公司 Method for detecting disintegration time of quick disintegration preparation
CN104422756A (en) * 2013-09-09 2015-03-18 北京量子高科制药科技有限公司 Disintegration time limit determination device for rapid disintegration preparation
CN111707791A (en) * 2020-06-28 2020-09-25 青海省药品检验检测院 Self-monitoring intelligent disintegration tester

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C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20120307

Termination date: 20140720

EXPY Termination of patent right or utility model