CN202141704U - Liquid phase adsorption chromatograph separating column - Google Patents
Liquid phase adsorption chromatograph separating column Download PDFInfo
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- CN202141704U CN202141704U CN201120208518U CN201120208518U CN202141704U CN 202141704 U CN202141704 U CN 202141704U CN 201120208518 U CN201120208518 U CN 201120208518U CN 201120208518 U CN201120208518 U CN 201120208518U CN 202141704 U CN202141704 U CN 202141704U
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- column
- sieve plate
- filler
- jecket
- liquid phase
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Abstract
The utility model discloses a liquid phase adsorption chromatograph separating column which comprises a bracket and a movable sieve plate. The bracket is arranged in the inner wall of a column pipe and is used for bearing the movable sieve plate; the movable sieve plate is arranged on a sieve plate bracket on the inner wall of the column pipe and is used for bearing packings. Different packings are filled at two sides of the movable sieve plate. The effect of simultaneously detecting and analyzing two components can be realized by one-time detecting through the structure, so that the detecting times are reduced, the detecting cost is reduced, the detecting speed is increased and the detecting efficiency is improved.
Description
Technical field
The utility model relates to separation, the analysis technical field of chemicals, relates in particular to a kind of liquid phase adsorption chromatography column.
Background technology
The liquid phase adsorption chromatographic separation technology is a kind of dynamical Physical Separation Technology, and its core component is a chromatography column.Its separation principle is: the blending ingredients sample is dissolved in a kind of moving phase; Moving phase is under the condition of bigger pressure; Flow through the chromatograph packing material (filler) of can in chromatography column with certain flow velocity, because chromatograph packing material is to the difference of the absorption affinity of different component, so different component will flow through chromatograph packing material with different flow rate; And detected components flows out in the detecting device of liquid chromatograph time and components contents, separate and the purpose that detects thereby reach.Chromatographic column is general to adopt high-grade stainless steel to process its inner wall smooth.The effect of sieve plate is to catch solid-phase adsorbent, prevents from separating column, to flow out the Interference Detection effect.
But in liquid phase adsorption chromatography column commonly used; Generally in separating column, only fill a kind of solid-phase adsorbent usually; Because specific solid-phase adsorbent has specific adsorption to specific chemical, the separating column of this structure once can only separate, the material of a certain molecular diameter or chemical property in the test sample.Yet in actual mechanical process, the component of the material that some is to be detected is more complicated often, will carry out separating for several times, analysis to multiple sample for detecting its component, and this will cause testing process length consuming time, and it is high to detect cost.Therefore, be necessary existing liquid phase adsorption chromatography column is further improved, detect number of times, reduce and detect cost, improve the purpose of detection speed to realize improving reducing.
The utility model content
The purpose of the utility model is to provide a kind of liquid phase adsorption chromatography column, and it can be realized improving reducing and detect number of times, reduces and detects cost, improves detection speed.
For realizing above-mentioned purpose, the utility model provides a kind of liquid phase adsorption chromatography column, and it comprises column cap, column jecket, fixed screen deck, filler, and said chromatography column also comprises support, and it is arranged at the inwall of column jecket, in order to carry active sieve plate; Active sieve plate, it is arranged on the sieve plate support of inwall of column jecket, in order to carry filler.
As the further improvement of the utility model, the filler of different absorption properties is filled in said active sieve plate both sides.
As the further improvement of the utility model, said column cap and column jecket are spirally connected, and can separate with the column jecket activity.
As the further improvement of the utility model, respectively be provided with a fixed screen deck on the internal face of the side that the column cap at said column jecket two ends and column jecket are spirally connected, be used for fixing the filler in the chromatography column.
As the further improvement of the utility model, the internal diameter of said column jecket is greater than the external diameter of active sieve plate.
As the further improvement of the utility model, said fixed screen deck and active sieve plate are circular.
Compared with prior art, a kind of liquid phase adsorption chromatography column of the utility model is employed on the inwall of column jecket support is set, and active sieve plate is set to carry second kind of filler on the support.Detected sample is with after organic solvent mixes; High pressure (135～185kgf) drive under; Get into the liquid chromatography separating column from the separating column inlet; And through two kinds of different fillers, according to different fillers the absorption of different component in the sample is had specific principle, thereby be implemented in the effect of the plurality of target component in the disposable sample separation in the same liquid chromatography separating column.This simple in structure, be easy in same liquid phase adsorption chromatography column, add two kinds of solid-phase adsorbents, active sieve plate also is easy to take out, installs and cleans simultaneously, detects number of times to realize improving reducing, and reduces and detects cost, improves the purpose of detection speed.
Description of drawings
Accompanying drawing is used to provide the further understanding to the utility model, is used to explain the utility model with each embodiment of the utility model, but does not constitute the restriction to the utility model.In the accompanying drawings:
Fig. 1 is the A-A cut-open view of not filling the liquid phase adsorption chromatography column of filler.
Fig. 2 is for filling the liquid phase adsorption chromatography column A-A cut-open view of first kind of filler.
Fig. 3 is for filling the liquid phase adsorption chromatography column A-A cut-open view of second kind of filler.
Embodiment
Describe below in conjunction with the preferred embodiment of accompanying drawing, should be appreciated that preferred embodiment described herein only is used for explanation and explains the utility model, and be not used in qualification the utility model the utility model.
A-A cut-open view referring to figs. 1 through a kind of liquid chromatography separating column in one embodiment of the utility model shown in 3.The chromatography separation principle is: be dissolved in when each component is through stationary phase in the moving phase (Mobile Phase); Because with the have an effect size, strong and weak different of (absorption, distribution, ion attraction, exclusion, affine) of stationary phase (Stationary Phase); The difference of hold-up time in stationary phase, thus successively from stationary phase, flow out.Liquid chromatography send out the incipient stage be with large diameter glass tube column under normal temperature and normal pressure with the liquid level difference transport flow mutually, claim " classical liquid phase chromatography ", the method inferior separating effect, length consuming time again.People have begun the method for research and utilization drive of high-pressure gas moving phase for this reason, claim again high performance liquid chromatography (High performance Liquid Chromatography, HPLC).Utilize this method carry out separation component efficient, fast, resolution is high, highly sensitive, so be called " MLC " again.Adopt the instrument of this kind technology just to be called " high performance liquid chromatograph ", its most important parts are exactly separating column.Separating column is generally processed by high-grade stainless steel; Inner wall smooth; Cavity wherein can be filled various fillers (stationary phase); Utilize different fillers that different component is had the absorption of specificity property, distribution, ion attraction, exclusion, affine effect, (mainstream technology adopts suction-operated at present) makes the different component difference of the hold-up time in stationary phase, thereby successively from stationary phase, flows out.And detect various components through detecting device and be cut into branch and the time of flowing out separating column really, thereby the purpose that reaches separations, detection, writes down.
In the present embodiment, a kind of liquid chromatography separating column comprises sample inlet column cap 60, column jecket 3, support 4, active sieve plate 21, fixed screen deck 20, sample export column cap 11.Adopt the mode secure fixation that is spirally connected guaranteeing sealing between sample export column cap 11 and the column jecket 3, and can be from movable separation the on the column jecket 3.Sample export column cap 11 and column jecket 3 are spirally connected and are provided with a fixed screen deck 20 in the middle of part inboard, in order to carry first kind of filler 5a in the separating column.The port that links to each other with column jecket 3 from sample inlet column cap 60 is then put into the height of column jecket 3 to support 4 with first filler, and is promptly shown in Figure 2.An active sieve plate 21 is set on the support in column jecket 34 then, in column jecket 3, fills the second filler 5b then near sample inlet joint 60 and column jecket 3.Adopt the mode secure fixation that is spirally connected to guarantee sealing sample inlet joint 60 and column jecket 3 at last, promptly shown in Figure 3.When the aperture 62 of the sample that contains two kinds of components from sample inlet column cap 60 flows into the column jecket 3, at first through the second filler 5b, because the wherein a certain middle component property of the second filler 5b specific adsorption; When sample continues to flow through the second filler 5a, the another kind of component of the second filler 5a specific adsorption.Because the difference of the absorption property of two kinds of components in different fillers also can be variant so flow out the time of chromatographic column, and finally in detecting device, be detected concrete component concentration and the time peak value that flows out chromatographic column.
In this embodiment, active sieve plate 21 carries the second filler 5b and the first filler 5a respectively with fixed screen deck 20.Can be in same separating column two kinds of components of disposable separation, detect number of times thereby reach to improve to reduce, reduce and detect cost, improve the purpose of detection speed.
Be to be understood that; Though this instructions is described according to embodiment; But be not that each embodiment only comprises an independently technical scheme, this narrating mode of instructions only is for clarity sake, and those skilled in the art should make instructions as a whole; Technical scheme among each embodiment also can form other embodiments that it will be appreciated by those skilled in the art that through appropriate combination.
The listed a series of detailed description of preceding text only is specifying to the feasibility embodiment of the utility model; They are not the protection domain in order to restriction the utility model, allly do not break away from equivalent embodiment or the change that the utility model skill spirit done and all should be included within the protection domain of the utility model.
Claims (6)
1. liquid phase adsorption chromatography column, comprising: column cap, column jecket, fixed screen deck, filler is characterized in that this chromatography column also comprises:
Support, it is arranged at the inwall of column jecket, in order to carry active sieve plate;
Active sieve plate, it is arranged on the sieve plate support of inwall of column jecket, in order to carry filler.
2. chromatography column according to claim 1 is characterized in that: the filler of different absorption properties is filled in said active sieve plate both sides.
3. chromatography column according to claim 1 is characterized in that: said column cap and column jecket are spirally connected, and can separate with the column jecket activity.
4. chromatography column according to claim 1 is characterized in that: respectively be provided with a fixed screen deck on the internal face of the side that the column cap at said column jecket two ends and column jecket are spirally connected, be used for fixing the filler in the chromatography column.
5. chromatography column according to claim 1 is characterized in that: the internal diameter of said column jecket is greater than the external diameter of active sieve plate.
6. chromatography column according to claim 1 is characterized in that: said fixed screen deck and active sieve plate are for circular.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201120208518U CN202141704U (en) | 2011-06-20 | 2011-06-20 | Liquid phase adsorption chromatograph separating column |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201120208518U CN202141704U (en) | 2011-06-20 | 2011-06-20 | Liquid phase adsorption chromatograph separating column |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202141704U true CN202141704U (en) | 2012-02-08 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201120208518U Expired - Lifetime CN202141704U (en) | 2011-06-20 | 2011-06-20 | Liquid phase adsorption chromatograph separating column |
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| Country | Link |
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| CN (1) | CN202141704U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102841167A (en) * | 2011-06-20 | 2012-12-26 | 苏州赛分科技有限公司 | Liquid chromatographic column |
-
2011
- 2011-06-20 CN CN201120208518U patent/CN202141704U/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102841167A (en) * | 2011-06-20 | 2012-12-26 | 苏州赛分科技有限公司 | Liquid chromatographic column |
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| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20120208 |
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| CX01 | Expiry of patent term |