CN202127705U - Environment simulation cabin for meiofauna experiment - Google Patents
Environment simulation cabin for meiofauna experiment Download PDFInfo
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- CN202127705U CN202127705U CN201120186376U CN201120186376U CN202127705U CN 202127705 U CN202127705 U CN 202127705U CN 201120186376 U CN201120186376 U CN 201120186376U CN 201120186376 U CN201120186376 U CN 201120186376U CN 202127705 U CN202127705 U CN 202127705U
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Abstract
The utility model discloses an environment simulation cabin for meiofauna experiment, which comprises an upper part and a lower part, wherein the simulation cabin is cuboid integrally, the upper half part is a working cabin which is provided with a toughened glass observation window at the front, and the lower half part is a motor cabin which is provided with two vacuum pumps and one compressor; a power supply of the vacuum pumps is connected with an alternative relay; the compressor is connected with a condenser through a pipeline; an intelligent pressure controller detecting end is connected with the straight end of an air releasing port; an output circuit is connected with a magnetic valve and a vacuum negative-pressure safety valve respectively; and a light controller is connected with an LED paster. The environment simulation cabin can be used for simulating various environments with normal pressure and low oxygen, low pressure and low oxygen, high heat, coldness, smog and gas. Pressure control, temperature control and lighting control are realized by adopting an automatic system, and manual monitoring and adjustment are not needed after parameter setting. The environment simulation cabin has high integration, attractive appearance, high safety factor and low manufacturing cost, and is simple to operate.
Description
Technical field
The utility model belongs to life science, medical research is used experimental facilities; Provide a kind of on the meiofauna experimental model; Simulation hypobaric hypoxia, normal pressure low oxygen, high temperature, cold and all gases and smog environment are used for life science and medical research under the particular surroundings.
Background technology
At present the large-scale environmental capsule of human has corresponding standard and standard by the manufacturing of domestic appointments enterprise; Animal is transformed voluntarily or is developed by the user with environmental capsule is many, does not seek unity of standard, and automaticity is low, is difficult to the industrialization volume production.This area research level and technical barrier are listed below at present:
(1) large-scale environmental capsule
Large-scale environmental capsule is used to carry out medical science, life science and the psychological study of particular surroundings kind, can carry out also that extreme environment adapts in advance, tolerance training before the art, physical training etc.The cabin body is generally rectangle, is welded by steel plate, and observation window etc. is housed on the bulkhead, and the seal of its door and window is all fine, and whole cabin body can bear big pressure.The cabin body is made up of two parts in cabin in separated and outer cabin, and wherein exhaust tube of each pass-out is connected with the vavuum pump of power house after two exhaust tubes pass through the by-pass valve control on the console.When completely cutting off, handle the rate of air sucked in required that two evacuating valves can be controlled inside and outside cabin respectively in inside and outside cabin; When inside and outside cabin communicates, only handle an evacuating valve and get final product.Inside and outside cabin also feeds an air inlet pipe respectively, and links to each other with air intake valve on the console, through valve scalable air inflow.Handle these valves, the ratio of bleeding regulating amount and air inflow can make in the cabin low air pressure condition that causes " rising ", " stop " or " decline ".Constantly extract gas in the cabin out with vavuum pump, can cause low gas hypoxia condition; Through feeding the low-oxygen gas mixture body of certain ratio, can cause the normal pressure low oxygen condition; Through refrigeration and firing equipment, can simulate cold or high thermal environment, or the like.
This environmental capsule is with artificial application, is produced by the special permission of domestic minority enterprise, and equipment manufacturing cost is high, easily just more than ten million RMB; Occupation area of equipment is big, generally needs 300m2 ground and 5m spatial altitude; Operation and Maintenance is complicated, need at least 4 professionals to operate simultaneously, and operating cost is expensive.For being the scientific research of object mainly, obviously be not suitable for using this large-scale environmental capsule with the meiofauna.
(2) minienvironment boiler-plate
The minienvironment boiler-plate supplies the small test animal to use, and current boiler-plate can only be created a kind of certain conditions, how to be developed voluntarily or to be transformed by the user.
The low temperature environment boiler-plate is formed by transformations such as refrigerator, low-temperature display cabinets, relies on the refrigeration of existing equipment and the simulation that temperature control system is realized low temperature environment; High thermal environment simulation cabin is many to be formed by the baking box transformation, and through the resistance wire heating, temperature controller is regulated temperature in the cabin, realizes the high heat condition in the cabin.
The normal pressure low oxygen environmental capsule constitutes the sealed compartment body by individual layer lucite and stainless steel metal plate; Air inlet connects nitrogen, carbonic acid gas, oxygen bottle; Gas concentration is monitored by sensing transducer, and the switching of control magnetic valve, makes that mixed gas concentration reaches preset level in the cabin.Direct and the atmosphere connection in gas outlet, so the cabin internal pressure keeps consistent with atmospheric pressure.In addition, this kind boiler-plate also is equipped with illumination, dehydrating unit, improves animal environment of living in.
Low-pressure oxygen cabin can be simulated the environment of hypobaric hypoxia, and is similar with the highlands air pressure conditions.The cabin body is cuboid or cylindric, is forged or welding favorable sealing property by steel plate.Hatch door generally leaves windowpane, is convenient to observe the animal activity situation.The hypobaric chamber gas outlet connects vavuum pump, and air descends pressure in the extraction cabin.Air inlet is an adjustable valve, is in closed condition when beginning to bleed, and when reaching the predetermined pressure position, through manual control air inflow, makes it to keep balance with the rate of air sucked in required of vavuum pump, to keep low-pressure state in the cabin.
Above-mentioned environmental capsule all can only be simulated single condition, and can't accomplish duplicating of complicated integrated condition, such as, not only there is hypoxemia under the altitude environment, also have environmental conditions such as cold, high ultraviolet ray.Secondly, these devices are mostly made by the user voluntarily, and are simple in structure, poor repeatability, and unstable properties, the standard disunity, safety is unsecured, is unfavorable for producing and promoting.In addition, the said equipment structure is disperseed, and automaticity is low, and a lot of parameters need manual adjustments and artificial control, and complicated operation and precision are relatively poor.
Summary of the invention
It is not enough that the purpose of the utility model is to overcome above-mentioned prior art, provides a kind of meiofauna experiment to use environmental capsule.
The technical scheme of the utility model is achieved in that
Comprise two parts up and down, integral body is cuboid, and the first half is a work chamber, is provided with the safety glass observation window before the work chamber, and the latter half is a motor room, is equipped with two vavuum pumps, a compressor; The power supply of vavuum pump is connected with relief relay, and exhaust tube is connected with the work chamber bleeding point; Compressor is connected with condenser tubes, and zone line is control display floater, assembling pointer pressure, temperature controller, CO
2Densimeter, intelligent pressure controller, lamp dimmer; The end of probe of pointer pressure communicates with inner bag in the work chamber bottom, and the temperature controller detecting head gos deep into inner bag, and out-put supply is connected with compressor with electric heater unit respectively, CO
2The sensor of densimeter (3) gos deep into inner bag through the work chamber bottom part aperture diameter, and intelligent pressure controller (6) end of probe is directly held with leakage port and is connected, and output circuit is connected with the negative pressure of vacuum safety valve with magnetic valve respectively, and lamp dimmer is connected with the LED paster.
Lamp dimmer is installed on the device panel, and control circuit detours to the observation window lower right corner from the work chamber door-hinge, and for the LED paster provides power supply, LED is attached at around the work chamber observation window outside, sees through safety glass illumination is provided in the cabin.
The utility model is tested as the use object with meiofauna.Mouse test is 40, and body weight (25 ± 5) g divides and supports in two breeding cages; Rat test is 16, and body weight (220 ± 30) g divides and supports in two breeding cages; The rabbit test is 4, and body weight (2.50 ± 0.75) Kg divides and supports in two breeding cages.Be 30 days each experimental period, equipment operation every day 23h.The equipment operational excellence, the main performance characteristic is following:
(1) pressure control is accurate, and the situation that pressure exceeds preset range does not appear in each pressure control valve no-float;
(2) animal is normal in the work intravehicular activity, and duration of test does not have animal dead, explains that this equipment throughput is fit to the meiofauna of above-mentioned quantity, CO in the equipment
2Concentration, humidity, temperature environment such as (not carrying out under the temperature adjustment situation) are suitable for animal survival;
(3) run duration is lower than 65 ℃ all the time in the motor room, the vaccum pump motor temperature does not reach the overtemperature protection temperature, connection and reasonable arrangement in the motor room, heat radiation is described well;
(4) under powering-off state, disappointing vacuum valve is opened, and in a single day when pressure rises to the atmospheric pressure level, the work hatch door is opened a slit automatically, prove accident power-off to occur, also can guarantee laboratory animal safety; Surpass following prescribing a time limit at pressure, antivoid valve is opened disappointing, avoids the animal hypoxia death, guarantees device security simultaneously.
Description of drawings
Fig. 1 is the structural representation of the utility model;
Fig. 2 is a pressure control section structure chart;
Fig. 3 is temperature control part separation structure figure;
Below in conjunction with accompanying drawing the content of the utility model is done further explain.
Embodiment
With reference to Fig. 1,2, shown in 3; The utility model is made up of cabin body, pressure control unit, temperature control unit, lighting control unit; To realize that the hypobaric hypoxia condition is the basis; Cold, the high heat condition that can superpose through inserting mist, can be realized normal pressure low oxygen, smog and all gases condition.At present that this system's formation and operation principle introduction is following:
(1) cabin body
Equipment standard appearance and size is 820 * 820 * 1700mm, and sheathing material is the roasting melamine of cold-rolled steel sheet.Top is work chamber 1, processes inner bag by stainless steel cold-rolled plate, and corresponding size is 600 * 600 * 600mm, and volume is about 216L, and the front portion is provided with 400 * 400mm safety glass observation window 2.The bottom is a motor room 8, is equipped with the vavuum pump 10 of two same sizes, compressor 9 etc.Equipment anteriomedial zone is equipped with pointer pressure 5, temperature controller 4, CO for the control display floater
2Densimeter 3, intelligent pressure controller 6, lighting controller 7 etc.Assembling universal wheel 11 in bottom is convenient to mobile device.
(2) pressure control section
Constitute by vavuum pump 10, relief relay 12, intelligent pressure controller 4, magnetic valve 14, negative pressure of vacuum safety valve 13 etc.Under the standard size, should adopt two speed of evacuations is the vavuum pump of 0.5L/S (pressure maintaining performance is good), and by relief relay control, making two vavuum pumps is that cycle wheel changes jobs with 1h.Leakage port is a three-way interface, and vertical end is installed magnetic valve (open type, 14); Straight end is installed programmable, intelligent pressure controller (relay system, 4), can set operating pressure (absolute pressure as requested; Promptly looking vacuum pressure is 0) upper and lower limit, and following lower limit, the upper limit is moved to switch on to magnetic valve; The lower limit action is magnetic valve 14 outages, the following open vacuum negative pressure relief valve 13 that is limited to.The negative pressure of vacuum safety valve is arranged on work chamber bottom, communicate with the work chamber inner bag, with the closed type magnetic valve as safety-valve.The leakage port vertical end of work chamber is installed magnetic valve 14, and straight end is installed intelligent pressure controller 6, and negative pressure of vacuum safety valve 13 is installed in the work chamber bottom; The action of the pressure controller upper limit, the actuating circuit that rolls off the production line are connected to magnetic valve, control its switch; Following lower limit circuit is connected to the negative pressure of vacuum safety valve, connects the back safety valve and opens.
(3) temperature control part branch
Constitute by temperature controller 4, electric heater unit 17, compressor 9, condenser 16 etc.Electric heater unit is positioned at work chamber inner bag bottom 18, and condenser is arranged in work chamber inner bag top 15, and compressor is positioned over motor room.Temperature controller 4 design temperatures when design temperature is higher than room temperature, start electric heater unit, cut off automatically behind the arrival design temperature; When design temperature is lower than room temperature, start compressor, temperature is cut off after dropping to the setting level automatically.Electric heater unit 17 is arranged in work chamber inner bag bottom 18, and condenser 16 is arranged in work chamber inner bag top 15, and compressor 9 is positioned over motor room; Temperature controller 4 is installed on the control panel, and its heating out-put supply is connected in electric heater unit, and the refrigeration out-put supply is connected in compressor.
(4) lighting unit
By delayed lamp optical controller 7, rectangular LED paster constitutes.The delayed lamp optical controller is installed on the device panel, can set lighting hours, and strip LED paster is attached at around the work chamber observation window outside, sees through safety glass illumination is provided in the cabin.
This operation of equipment flow process is following:
(1) laboratory animal is put into work chamber, close hatch door;
(2) energized 220V and 24V power supply;
(3) regulate the upper limit, lower limit of intelligent pressure controller, lower limit (suggestion is absolute pressure 200mmHg) down according to requirement of experiment;
(4) adjust experimental temperature as requested, or carry out the setting of temperature dynamic fluctuation;
(5), is set the time delay of light control according to requirement of experiment;
(6) open vacuum pump, cabin internal gas pressure begin to descend;
(7) by the time pressure rises to institute's level-off, observes the whether normal opening and closing of leakage port magnetic valve;
(8) open the work chamber locking system, in case animal is suffocated behind the accident power-off;
(9) after experiment finishes, powered-down, air pressure gos up automatically; Treat with the atmospheric pressure balance after, opened door takes out animal, clears up;
(10) through feeding low-oxygen gas mixture body, smog or other gas, get final product simulated normal pressure hypoxemia and all gases environment from leakage port; When feeding toxic gas, the work chamber bleeding point should install gas additional to be collected or harmless treatment device.
Claims (2)
1. environmental capsule is used in the meiofauna experiment, comprises two parts up and down, and integral body is cuboid; It is characterized in that the first half is work chamber (1), the preceding safety glass observation window (2) that is provided with of work chamber (1); The latter half is motor room (8), is equipped with two vavuum pumps (10), a compressor (9); The power supply of vavuum pump (10) is connected with relief relay (12), and exhaust tube is connected with work chamber (1) bleeding point; Compressor is connected with condenser (17) pipeline, and zone line is control display floater, assembling pointer pressure (5), temperature controller (4), CO
2Densimeter (3), intelligent pressure controller (6), lamp dimmer (7); The end of probe of pointer pressure communicates with inner bag in the work chamber bottom, and temperature controller (4) detecting head gos deep into inner bag, and out-put supply is connected CO with electric heater unit (17) respectively with compressor
2The sensor of densimeter (3) gos deep into inner bag through the work chamber bottom part aperture diameter; Intelligent pressure controller (6) end of probe is directly held with leakage port and is connected; Output circuit is connected with negative pressure of vacuum safety valve (13) with magnetic valve (14) respectively, and lamp dimmer (7) is connected with the LED paster.
2. environmental capsule is used in meiofauna experiment according to claim 1; It is characterized in that; Lamp dimmer (7) is installed on the device panel, and control circuit detours to observation window (2) lower right corner, for the LED paster provides power supply from the work chamber door-hinge; LED is attached at around the work chamber observation window outside, sees through safety glass illumination is provided in the cabin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201120186376U CN202127705U (en) | 2011-06-03 | 2011-06-03 | Environment simulation cabin for meiofauna experiment |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201120186376U CN202127705U (en) | 2011-06-03 | 2011-06-03 | Environment simulation cabin for meiofauna experiment |
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| CN202127705U true CN202127705U (en) | 2012-02-01 |
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| CN201120186376U Expired - Fee Related CN202127705U (en) | 2011-06-03 | 2011-06-03 | Environment simulation cabin for meiofauna experiment |
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Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103913412A (en) * | 2014-04-22 | 2014-07-09 | 苏州华周胶带有限公司 | Tape vacuum aging box |
| CN104799967A (en) * | 2015-04-29 | 2015-07-29 | 山东大学 | Integrated hypoxia experiment simulation device and method of mammals |
| CN106066377A (en) * | 2016-06-15 | 2016-11-02 | 中国人民解放军第三军医大学第三附属医院 | A kind of simple biological negative pressure cab |
| CN106781950A (en) * | 2017-01-03 | 2017-05-31 | 中国人民解放军第八医院 | A kind of multi-functional smog for medical research is caused injury experimental facilities |
| CN107578660A (en) * | 2016-08-08 | 2018-01-12 | 吉林壹舟医疗科技有限公司 | A kind of circuit breaking protective system of hypobaric chamber |
| CN107570220A (en) * | 2016-09-26 | 2018-01-12 | 吉林壹舟医疗科技有限公司 | A kind of cabin that can form environment under low pressure |
| CN110320942A (en) * | 2019-05-31 | 2019-10-11 | 吉林省农业科学院 | Open type animal breath calorimetric device |
| CN110623807A (en) * | 2019-09-24 | 2019-12-31 | 宁波大学 | Animal operation box capable of simulating high-stress environment |
| CN111328724A (en) * | 2020-04-01 | 2020-06-26 | 中国人民解放军总医院 | Animal experiment platform |
| CN113288655A (en) * | 2021-05-25 | 2021-08-24 | 福建誉神医学科技有限公司 | Control method of intermittent high-low pressure rehabilitation physiotherapy cabin |
| CN113638626A (en) * | 2021-07-07 | 2021-11-12 | 武汉蓝辉机电设备有限公司 | Color-changeable lamp box wall body of control room |
| CN113907014A (en) * | 2021-12-13 | 2022-01-11 | 天津医科大学总医院空港医院 | Pressure vessel cabin of low-pressure and low-oxygen animal model cabin |
| CN113917964A (en) * | 2021-12-13 | 2022-01-11 | 仙人长(天津)医疗科技有限公司 | Control system for maintaining stability of environment in low-pressure and low-oxygen animal model cabin |
| CN117158331A (en) * | 2023-10-19 | 2023-12-05 | 中国人民解放军总医院第六医学中心 | Temperature-controllable high-low pressure dual-purpose animal experiment cabin |
-
2011
- 2011-06-03 CN CN201120186376U patent/CN202127705U/en not_active Expired - Fee Related
Cited By (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103913412A (en) * | 2014-04-22 | 2014-07-09 | 苏州华周胶带有限公司 | Tape vacuum aging box |
| CN104799967A (en) * | 2015-04-29 | 2015-07-29 | 山东大学 | Integrated hypoxia experiment simulation device and method of mammals |
| CN104799967B (en) * | 2015-04-29 | 2017-03-15 | 山东大学 | Integral type mammal anoxic experimental simulation device and method |
| CN106066377A (en) * | 2016-06-15 | 2016-11-02 | 中国人民解放军第三军医大学第三附属医院 | A kind of simple biological negative pressure cab |
| CN107578660A (en) * | 2016-08-08 | 2018-01-12 | 吉林壹舟医疗科技有限公司 | A kind of circuit breaking protective system of hypobaric chamber |
| CN107570220A (en) * | 2016-09-26 | 2018-01-12 | 吉林壹舟医疗科技有限公司 | A kind of cabin that can form environment under low pressure |
| CN107570220B (en) * | 2016-09-26 | 2024-04-26 | 吉林壹舟医疗科技有限公司 | Cabin capable of forming low-pressure environment |
| CN106781950A (en) * | 2017-01-03 | 2017-05-31 | 中国人民解放军第八医院 | A kind of multi-functional smog for medical research is caused injury experimental facilities |
| CN110320942B (en) * | 2019-05-31 | 2022-10-11 | 吉林省农业科学院 | Open-circuit animal breath heat measuring device |
| CN110320942A (en) * | 2019-05-31 | 2019-10-11 | 吉林省农业科学院 | Open type animal breath calorimetric device |
| CN110623807A (en) * | 2019-09-24 | 2019-12-31 | 宁波大学 | Animal operation box capable of simulating high-stress environment |
| CN111328724A (en) * | 2020-04-01 | 2020-06-26 | 中国人民解放军总医院 | Animal experiment platform |
| CN113288655A (en) * | 2021-05-25 | 2021-08-24 | 福建誉神医学科技有限公司 | Control method of intermittent high-low pressure rehabilitation physiotherapy cabin |
| CN113638626A (en) * | 2021-07-07 | 2021-11-12 | 武汉蓝辉机电设备有限公司 | Color-changeable lamp box wall body of control room |
| CN113638626B (en) * | 2021-07-07 | 2024-04-16 | 武汉蓝辉机电设备有限公司 | Wall body of color-changeable lamp box of control room |
| CN113907014A (en) * | 2021-12-13 | 2022-01-11 | 天津医科大学总医院空港医院 | Pressure vessel cabin of low-pressure and low-oxygen animal model cabin |
| CN113917964A (en) * | 2021-12-13 | 2022-01-11 | 仙人长(天津)医疗科技有限公司 | Control system for maintaining stability of environment in low-pressure and low-oxygen animal model cabin |
| CN113907014B (en) * | 2021-12-13 | 2022-03-11 | 天津医科大学总医院空港医院 | Pressure vessel cabin of low-pressure and low-oxygen animal model cabin |
| CN117158331A (en) * | 2023-10-19 | 2023-12-05 | 中国人民解放军总医院第六医学中心 | Temperature-controllable high-low pressure dual-purpose animal experiment cabin |
| CN117158331B (en) * | 2023-10-19 | 2024-05-10 | 中国人民解放军总医院第六医学中心 | Temperature-controllable high-low pressure dual-purpose animal experiment cabin |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120201 Termination date: 20120603 |