CN201995441U - Dementia rat labyrinth type intellectual rehabilitation training device - Google Patents

Dementia rat labyrinth type intellectual rehabilitation training device Download PDF

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Publication number
CN201995441U
CN201995441U CN2010205602813U CN201020560281U CN201995441U CN 201995441 U CN201995441 U CN 201995441U CN 2010205602813 U CN2010205602813 U CN 2010205602813U CN 201020560281 U CN201020560281 U CN 201020560281U CN 201995441 U CN201995441 U CN 201995441U
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labyrinth
overhead
type
plate
training
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刘罡
谢鸿宇
贾杰
张峰
吴毅
胡秀枋
邹任玲
赵展
徐秀林
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Huashan Hospital of Fudan University
University of Shanghai for Science and Technology
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Huashan Hospital of Fudan University
University of Shanghai for Science and Technology
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Abstract

The utility model provides a dementia rat labyrinth type intellectual rehabilitation training device. The dementia rat labyrinth type intellectual rehabilitation training device comprises a plurality of layers of training cages that are arranged in a stacking manner, the adjacent training cages are nested with one another and communicated through a ladder, and labyrinths are arranged in the training cages and comprise a leisure labyrinth, a plug board labyrinth, an overhead tremble labyrinth and a refuge pocket labyrinth that are combined at will. In the utility model, a willing action labyrinth type learning and memorizing training device is constructed by utilizing the natural behavioral performances of conditional reflex of the dementia rats, the behavioral function performances of the dementia rats are promoted by utilizing a new, changeable, interesting, comfortable and active learning and memorizing labyrinth type training space, the space learning capacity and memorizing capacity can be improved, and the searching capacity and repeating capacity of animals can be reflected accurately and objectively, which facilitates the improvement and the evaluation of learning and memorizing functions of patients with senile dementia, and being of of great importance in quickening the rehabilitation speed.

Description

Dementia rats labyrinth type intellectual rehabilitation trainer
Technical field
The utility model relates to a kind of analog training device, relates in particular to a kind of dementia rats labyrinth type intellectual rehabilitation trainer.
Background technology
Senile dementia mainly comprises Alzheimer ' s disease and vascular dementia, is the elderly's one of the most serious disease that disables, and therefore the learning and memory method of rehabilitation of senile dementia being sought and studied is a pressing problem of current medical circle.
The inside psychology and the intelligence of humans and animals can't observe directly, and can only infer the process that takes place in the brain according to interval certain hour after observable irritant reaction and a certain task of execution.Good animal model is the basis of carrying out this disease research.Set up the senile dementia animal model essence and the rehabilitation of being familiar with disease had important role.Therefore developing a kind of medical institutions, scientific research institution can widely used dementia rats intellectual rehabilitation trainer, significant.
The labyrinth training is by the stimulation to each sense organ, make the reorganization of cortex somatesthesia moving loop, the plastic enhancings of brain function such as mouse structure plasticity, learning and memory are all had a significant effect, sensorimotor and learning and memory function are enhanced, for delaying senility, promote intelligence certain effect being arranged also, is a kind of simple and effective therapy rehabilitation means.At present, medical institutions use wind, illumination, electric shock class labyrinth to force mouse memory and run away mostly, and strong to the mouse excitant, nocuity is big; Also some research institution uses water maze, mouse forced be placed in the water, utilize mouse to dislike nature movable in water and force mouse memory and climbing disembarkation, all mouse will be dried up after training each time or the test, operation is trouble, and is often more with the sick mouse in training back after tested.Above labyrinth all has the mandatory of stimulus to the sense organ; be a kind of punishment not only to mouse; be unfavorable for protection of animals; and easily cause stewed mental element; be difficult to get rid of the influence of the non-study factors such as dyskinesia, injury of self to the experiment observation index; influence test accuracy, seek for the learning and memory method of rehabilitation of senile dementia disease and research brings difficulty.
The utility model content
The purpose of this utility model exactly in order to address the above problem, provides a kind of dementia rats labyrinth type intellectual rehabilitation trainer.
In order to achieve the above object, the utility model has adopted following technical scheme: a kind of dementia rats labyrinth type intellectual rehabilitation trainer, comprise multilayer training cage, multilayer training cage stacked on top of one another is provided with, and mutually nestedly between the adjacent training cage links to each other and is communicated with by ladder; Be provided with the labyrinth in the described training cage, described labyrinth comprises leisure labyrinth, plate labyrinth, overhead anxiety labyrinth and refuge pocket labyrinth, and various labyrinths can be made up setting arbitrarily.
Described leisure labyrinth comprises duct type labyrinth and crock formula labyrinth; The duct type labyrinth comprises a plurality of threading a pipe of two passwaies that have at least more, and the ladder of upwards climbing for mouse is installed in pipeline; Crock formula labyrinth comprises the big crock of a plurality of young tripes, and at the bottom of being provided with a plurality of rope ladders and extending to cage from the top oral area of each crock respectively, wherein is stamped lid on the mouth of some crock, does not have lid on the mouth of other crocks.
Described plate labyrinth comprises the horizontal plate of polylith, the vertical plate of polylith and polylith baffle plate; Be equipped with a plurality of equally spaced door openings and be used for the draw-in groove that mutual sleeve links to each other on each horizontal plate and each vertical plate, form a plurality of criss-cross room by continuous being staggered of corresponding draw-in groove sleeve between each horizontal plate and each the vertical plate, the polylith baffle plate optionally hangs over the door opening that blocks this plate on the different plates, thereby form the labyrinth of different routes, comprise the labyrinth of T type route, U type route, cross route.
Described overhead anxiety labyrinth is to set up an overhead annex to form on the board plug type labyrinth, take two-layer training cage, high shelf attachment will be positioned at the sealing suitable for reading in the corresponding criss-cross room in the board plug type labyrinth below it, overhead annex comprises that an overhead long slab and two hide the unit, hiding the unit for two is symmetricly set on the both sides of overhead long slab and forms decussate texture with overhead long slab, hiding the unit for two respectively comprises two criss-cross rooms and be respectively equipped with door opening on each dividing plate that distributes along its length, each door opening optionally blocks with baffle plate, hides unit inside bottom for two and is respectively equipped with ladder and leads to following board plug type labyrinth.
Described refuge pocket labyrinth is to put on the shelf at the high shelf attachment in overhead anxiety labyrinth to establish that refuge pocket is dull and stereotyped to be formed, and is provided with a plurality of duck eyes that penetrate platform around the refuge pocket flat board, and one of them duck eye has one that ladder leads in the high shelf attachment to hide the unit.
The utility model utilizes the non-human act performance of the conditioned reflex of dementia rats, make up voluntary activity maze learning memory training device, utilize by fresh changeable, entertaining is comfortable, the space is trained in glad movable learning and memory labyrinth, promote the improvement of dementia form mouse behavioral function performance, improve the space learning ability, memory capability, relatively accurately reflect search capability and the repetition ability of animal objectively, the learning and memory function that helps senile dementia improves and evaluation, accelerate the rehabilitation process, significant.
Dementia rats labyrinth type intellectual rehabilitation trainer of the present utility model makes it have following advantage and characteristics owing to adopted above technical scheme:
(1) all detachably assemblings of cage and labyrinth, the convenient cleaning carried.
(2) the leisure labyrinth comprises duct type labyrinth, crock formula labyrinth etc.
(3) the board plug type labyrinth can conveniently be transformed into the different difficulty labyrinth of T type, U type, cross labyrinth, any route.
(4) board plug type labyrinth and corresponding accessory are used in combination and can construct overhead anxiety labyrinth, hide type labyrinth etc.
Description of drawings
Fig. 1 is the general structure schematic diagram of the utility model dementia rats labyrinth type intellectual rehabilitation trainer;
Fig. 2 is the structural representation in the leisure labyrinth in the utility model;
Fig. 3 is the structural representation of the horizontal plate in the utility model;
Fig. 4 is the structural representation of the vertical plate in the utility model;
Fig. 5 is the structural representation of the baffle plate in the utility model;
Fig. 6 is the structural representation in the T type labyrinth in the utility model;
Fig. 7 is the structural representation in the U type labyrinth in the utility model;
Fig. 8 is the structural representation in the cross labyrinth in the utility model;
Fig. 9 is the structural representation in the different difficulty labyrinth of any route in the utility model;
Figure 10 is the partial structurtes schematic diagram in the overhead anxiety labyrinth in the utility model;
Figure 11 is the partial structurtes schematic diagram in the refuge pocket labyrinth in the utility model.
Embodiment
Below in conjunction with accompanying drawing dementia rats labyrinth type intellectual rehabilitation trainer of the present utility model is described further, accompanying drawing is depicted as a preferred embodiment of the present utility model, and the utility model is not limited to present embodiment.
Referring to Fig. 1, dementia rats labyrinth type intellectual rehabilitation trainer of the present utility model comprises multilayer training cage 1,2,3,4, and multilayer training cage stacked on top of one another is provided with, and mutually nestedly between the adjacent training cage links to each other and is communicated with by ladder; Be provided with the labyrinth in the training cage, comprise leisure labyrinth, plate labyrinth, overhead anxiety labyrinth and refuge pocket labyrinth, various labyrinths can be made up setting arbitrarily.The basic structure of each training cage comprises rectangular frame and base plate of a band peep hole, and the labyrinth is arranged on the base plate.On the superiors' training cage, be provided with a cover plate.
Referring to Fig. 2, the leisure labyrinth in the utility model comprises duct type labyrinth 11 and crock formula labyrinth 12; Duct type labyrinth 11 comprises a plurality of threading a pipe of two passwaies that have at least, for example bipass road, three-way pipeline, four-way pipeline, five-way pipeline etc. more.In the vertical pipeline that is provided with, the ladder of upwards climbing for mouse is installed.Crock formula labyrinth 12 comprises the big crock of a plurality of young tripes, and at the bottom of being provided with a plurality of rope ladders 13 and extending to cage from the top oral area of each crock respectively, wherein is stamped lid 14 on the mouth of some crock, does not have lid on the mouth of other crocks.The crock the inside of being stamped lid does not have food, does not have the crock the inside of lid that food is housed, and mouse is down below the time, can't see crock whether lid is arranged, could find after can only climbing up rope ladder that mouse is by after the study of a period of time, can nature remember and makes great efforts to climb the crock that food is housed.
Referring to Fig. 3, Fig. 4, Fig. 5, Fig. 6, Fig. 7, Fig. 8, Fig. 9, the plate labyrinth in the utility model comprises the horizontal plate 21 of polylith (referring to Fig. 3), the vertical plate 22 of polylith (referring to Fig. 4) and polylith baffle plate 23 (referring to Fig. 5); Be equipped with a plurality of equally spaced door openings 211,221 and be used for the draw-in groove 212,222 that mutual sleeve links to each other on each horizontal plate 21 and each vertical plate 22, form a plurality of criss-cross room 24 by continuous being staggered of corresponding draw-in groove sleeve between each horizontal plate 21 and each the vertical plate 22, polylith baffle plate 23 optionally hangs over the door opening that blocks this plate on the different plates, thereby form the labyrinth of different routes, comprise the labyrinth of T type route, U type route, cross route.Figure 6 shows that T type route labyrinth, Figure 7 shows that U type route labyrinth, Figure 8 shows that cross route labyrinth, Figure 9 shows that any route labyrinth.The labyrinth training that all kinds of difficulty are different can progressively improve spatial memory ability and the abilities such as resolving ability, study cognition of ill mouse.The high size of whole length and width in board plug type labyrinth generally can be climbed up and over height according to the area of layer, mouse size and its and be decided.The board plug type labyrinth is detachable, and convenient the cleaning installed, and can place diet box as award at place, unit, required labyrinth, also can place telescopic ladder, expands activity space.
Referring to Figure 10, overhead anxiety labyrinth in the utility model is to set up an overhead annex to form on the board plug type labyrinth, take two-layer training cage, high shelf attachment will be positioned at the sealing suitable for reading in the corresponding criss-cross room in the board plug type labyrinth below it, overhead annex comprises that an overhead long slab 31 and two hide unit 32, hiding unit 32 for two is symmetricly set on the both sides of overhead long slab 31 and forms decussate texture with overhead long slab, hiding the unit for two respectively comprises two criss-cross rooms and be respectively equipped with door opening 33 on each dividing plate that distributes along its length, each door opening optionally blocks with baffle plate, hides two of unit for two and hides the unit inside bottom and be respectively equipped with ladder and lead to following board plug type labyrinth.The high-altitude anxiety of ill mouse can be progressively improved in overhead anxiety labyrinth, improves abilities such as memory capability and escape conditioned reflex.
Referring to Figure 11, refuge pocket labyrinth in the utility model is to put on the shelf at the high shelf attachment in overhead anxiety labyrinth to establish dull and stereotyped 41 compositions of forming of a refuge pocket, be provided with a plurality of duck eyes 42 that penetrate platform around the refuge pocket flat board 41, one of them duck eye has one that ladder 43 leads in the high shelf attachment to hide the unit, as the place of hiding of laboratory animal; Other duck eye is unsettled, can't lead to the unit of hiding in overhead anxiety labyrinth from this duck eye, forms the refuge pocket labyrinth, helps learning ability and memory capability rehabilitation.
The assemble method of dementia rats labyrinth type intellectual rehabilitation trainer of the present utility model is:
At first in ground floor training cage, the leisure labyrinth is set, places duct type labyrinth, crock formula labyrinth, rope ladder, scalable ladder etc.The second layer that superposes then training cage, assembling board plug type labyrinth in second layer training cage, the different difficulty labyrinth of formation capable of being combined such as T type, U type, cross, any route etc.The 3rd layer of training cage (removing base plate) that superpose again placed high shelf attachment in the 3rd layer of training cage, be combined to form overhead anxiety labyrinth with the board plug type labyrinth of the second layer; Superpose again the 4th layer and train cage (removing base plate), in the 4th layer of training cage, place the refuge pocket flat board, be combined to form the refuge pocket labyrinth with overhead anxiety labyrinth.
Above-mentioned is one of them implementation process, and when reality was used, changeable training number of plies amount changed cage height or training layer height, also can be arbitrarily made with double-deck training cage or individual layer training cage or the like.
Board plug type labyrinth in the utility model is when making up, and the labyrinth element number of structure is many more, and then the space of each unit, labyrinth is less.When removing some horizontal plate or vertical plate, the labyrinth element number of structure is less but the space is bigger.Generally, in unit, a labyrinth, 4 door openings are arranged at most, block wherein two passages, then form the one-in-and-one-out passage if hang up two baffle plates as passage.If adjacent with it unit, labyrinth also is the one-in-and-one-out passage, form unit, the easiest labyrinth, degree-of-difficulty factor is 1; Block one of them passage if hang the lastblock baffle plate, then form the one-in-and-two-out passage, if adjacent with it unit, labyrinth also is the one-in-and-two-out passage, then degree-of-difficulty factor then is 4; If the plate of not putting into gear, form one and advance three and go out passage, if also be into three to go out passage in it adjacent unit, labyrinth, then degree-of-difficulty factor is 27.This shows that the board plug type labyrinth can indiscriminately ad. as one wishes make up the different difficulty labyrinth of any route.
Below be example with T type route labyrinth, the embodiment of board plug type maze learning and memory training is described:
(1) construction method in T type route labyrinth
T type route labyrinth when all horizontal plates with after vertically plate all assembles, is opened the door opening of all the vertical plates between cage wall and the adjacent transverse plate, and is closed other door opening of all vertical plates as shown in Figure 6; The middle door opening of open all horizontal plates is closed other door openings, has then formed to comprise 2 T type labyrinths of selecting an arm (the laterally two ends of plate) and a beginning arm (a vertically end of plate).Mouse is placed on beginning arm end, diet box is placed on two in T type labyrinth selects the arm end, selecting arm and beginning arm intersection region is the center.T type labyrinth can be used for studying space learning, alternative behavior, condition identification learning and working memory.
(2) learning process:
In the selection arm end diet box of turning left, place food, in the selection arm end food boxes of turning right, do not place food, mouse is placed on beginning arm end, closing center turns left in the district and selects the arm inlet and turn right and select the arm inlet according to the order of sequence respectively, allow the cognitive arm inlet of selecting from turning left of mouse study that food is arranged, select the arm inlet not have food from turning right, allow mouse in the labyrinth, learn 20-30 minute, be familiar with and the adaptation labyrinth.
(3) memory process
A. simultaneously the open center district turns left and selects the arm inlet and turn right and select the arm inlet, observe that mouse enters the number of times of correct selection arm and time, the number of times of wrong choice arm and time, in time of staying of center.Test in this way and train under the regular situation memory capability of mouse.
B. after test after a while, food is placed on turns right again selects in the diet box of arm end, when observing mouse conversion probing direction once more, mouse enters the number of times of correct selection arm and time, the number of times of wrong choice arm and time, in time of staying of center.Test in this way and train under the simple change situation memory capability of mouse.
C. again after test after a while, select only to place a food in the arm end diet box left and right turning respectively, only under the situation that bilateral food is all eaten up, just place a food at bilateral once more, when observing mouse conversion probing direction once more, mouse enters the number of times of correct selection arm and time, the number of times of wrong choice arm and time, in time of staying of center.Test in this way and train under the complicated situation of change memory capability of mouse.
(3) observation index:
When observing animal and not having conversion probing direction under stress situation, non-human act under the comparison condition of former experience and present environment shows, with mouse enter the number of times and the time of correct selection arm, the number of times that enters the wrong choice arm and time, reference index in time of staying of center as learning and memory.And this behavior is subjected to the memory influence, and free interval of three stages in the experiment is to guarantee that animal is to being familiar with the memory degree of arm.
Other plate labyrinths such as U type route labyrinth are as shown in Figure 7, cross route labyrinth as shown in Figure 8, the route labyrinth as shown in Figure 9 arbitrarily, its building mode is similar to T type labyrinth, and difference is baffle plate is hung on the required diverse location, blocks corresponding door opening, just do not hang any baffle plate if will make up highly difficult labyrinth, will find food if mouse is placed on central area this moment, and the difficulty requirement of learning and memory has just been well imagined!
Overhead anxiety labyrinth
(1) construction method in overhead anxiety labyrinth
Overhead anxiety labyrinth is formed by board plug type labyrinth and overhead annex composite construction as shown in figure 10.On the board plug type labyrinth, increase the high shelf attachment of one deck, high shelf attachment by overhead long slab 31 with hide unit 32 with vertical 2 of linking to each other of overhead long slab and form, overhead long slab 31 is as open arms, hide unit 32 as closure arm, hiding the unit can become and really hide the unit, promptly open interior hole 33 of hiding the unit, there is the diet box that food is housed inboard, interior hole, and ladder 34 towards the board plug type labyrinth arranged, hide the unit and also can close the interior hole 33 of hiding the unit, become vacation and hide the unit, can only walk out once more after mouse enters, again to overhead long slab; High shelf attachment is placed on top, board plug type labyrinth, and making both sides, overhead long slab below all is each empty unit, labyrinth, finishes the experiment place with this and builds, and forms overhead anxiety labyrinth.This labyrinth utilizes animal that novel environment probed into habit and the contradiction state that the fear of uphanging out arm is formed animal, anxiety and the memory capability of reflection animal.
(2) learning process:
Make a left side hide the unit for really hiding the unit, it is that the unit is hidden in vacation that the unit is hidden on the right side, and mouse is placed on overhead long slab starting end, and anxiety walking on overhead long slab, allows mouse study find and really hides the unit, and learnt 20-30 minute in the labyrinth, is familiar with and the adaptation labyrinth.
(3) memory process:
A. at interval 10 minutes, observe mouse enter the true and false number of times of hiding the unit and entry time, in time of staying of open arms and closure arm.Test in this way and train under the regular situation anxiety and the memory capability of mouse under overhead anxiety situation.
B. the interval is 10 minutes, the right side is hidden the unit for true again, and the unit is hidden for false in a left side, and the observation mouse enters true and false number of times and the entry time of hiding the unit, in the time of staying of open arms and closure arm.Again after test after a while, make simultaneously and true and falsely hide the unit and be very, observe mouse enter the number of times of hiding the unit and entry time, in time of staying of open arms and closure arm.Test in this way and train under the simple change situation overhead anxiety situation and the memory capability of mouse under overhead anxiety situation.
(4) observation index:
Be used to test the memory capability of mouse under overhead anxiety situation by entering true and false number of times and the entry time of hiding the unit; Enter the number of times of open arms and be used for the pinnacled anxiety degree of test animal in the open arms holdup time; Animal enters open arms and closure arm number of times, in open arms and closure arm and run duration, move distance in the central area of labyrinth, with enter open arms number of times and the percentage of always going into the arm number of times when in open arms the percentage of the total time in run duration and the open arms closure arm represent the angst resistance effect index.
The refuge pocket labyrinth
(1) construction method in refuge pocket labyrinth
The refuge pocket labyrinth is used to assess space learning and memory capability.On overhead anxiety labyrinth, increase one deck refuge pocket flat board 41, the refuge pocket flat board is made of the square platform that a periphery is covered with the duck eye 42 that much penetrates platform, refuge pocket flat board 41 is placed top, overhead anxiety labyrinth, in all holes, have only bottom, a hole to have ladder 43 to lead to overhead anxiety labyrinth and really hide unit 32, be called the target hole, in the diet box that food is housed is arranged, become the place of hiding of laboratory animal; The bottom in other hole is unsettled, does not hide the place, finishes the experiment place with this and builds, and forms and hides the type labyrinth.The refuge pocket labyrinth does not need high light, wind and electric shock, therefore to animal stress be less.Experiment is very little for the physical fitness requirement of animal, can MIN minimizing because of the influence of the physically-draining due to the age factor to experimental result, the thickness of its platform, width of cave entrance and number are different and different according to the laboratory animal size dimension.
(2) learning process:
During each training beginning mouse is placed on the dull and stereotyped central authorities in refuge pocket labyrinth, the visual reference thing that animal use provides is effectively determined the position at place, target hole.Allow mouse on the refuge pocket flat board, learn to be familiar with and to adapt in 20-30 minute the labyrinth.The each training of mouse is all carried out wiping with alcohol to the labyrinth later, and rotation refuge pocket labyrinth flat board, but does not change the relative tertiary location in target hole, seeks food to prevent information such as mouse utilization smell.
(3) memory process:
Between isolated 10 minutes, observe the number of times at mouse target approach hole and wrong hole and entry time, time of staying of dull and stereotyped central authorities in the refuge pocket labyrinth.Test in this way and train under the regular situation, measure the spatial memory ability of animal for the target hole.
(4) observation index:
Recording laboratory animal finds the time at correct hole, and enters the georeferencing memory capability of the number of times at wrong hole with the reaction animal, also can repeat to enter wrong hole number by the record animal and measure the working memory of animal.

Claims (5)

1. dementia rats labyrinth type intellectual rehabilitation trainer is characterized in that: comprise multilayer training cage, multilayer training cage stacked on top of one another is provided with, and mutually nestedly between the adjacent training cage links to each other and is communicated with by ladder; Be provided with the labyrinth in the described training cage, described labyrinth comprises leisure labyrinth, plate labyrinth, overhead anxiety labyrinth and refuge pocket labyrinth, the setting capable of being combined of various labyrinths.
2. dementia rats labyrinth type intellectual rehabilitation trainer as claimed in claim 1 is characterized in that: described leisure labyrinth comprises duct type labyrinth and crock formula labyrinth; The duct type labyrinth comprises a plurality of threading a pipe of two passwaies that have at least more, and the ladder of upwards climbing for mouse is installed in pipeline; Crock formula labyrinth comprises the big crock of a plurality of young tripes, and at the bottom of being provided with a plurality of rope ladders and extending to cage from the top oral area of each crock respectively, wherein is stamped lid on the mouth of some crock, does not have lid on the mouth of other crocks.
3. dementia rats labyrinth type intellectual rehabilitation trainer as claimed in claim 1, it is characterized in that: described plate labyrinth comprises the horizontal plate of polylith, the vertical plate of polylith and polylith baffle plate; Be equipped with a plurality of equally spaced door openings and be used for the draw-in groove that mutual sleeve links to each other on each horizontal plate and each vertical plate, form a plurality of criss-cross room by continuous being staggered of corresponding draw-in groove sleeve between each horizontal plate and each the vertical plate, the polylith baffle plate can hang over the door opening that blocks this plate on the different plates, thereby form the labyrinth of different routes, comprise the labyrinth of T type route, U type route, cross route.
4. dementia rats labyrinth type intellectual rehabilitation trainer as claimed in claim 1, it is characterized in that: described overhead anxiety labyrinth is to set up an overhead annex to form on the board plug type labyrinth, take two-layer training cage, high shelf attachment will be positioned at the sealing suitable for reading in the corresponding criss-cross room in the board plug type labyrinth below it, overhead annex comprises that an overhead long slab and two hide the unit, hiding the unit for two is symmetricly set on the both sides of overhead long slab and forms decussate texture with overhead long slab, hiding the unit for two respectively comprises two criss-cross rooms and be respectively equipped with door opening on each dividing plate that distributes along its length, each door opening optionally blocks with baffle plate, hides unit inside bottom for two and is respectively equipped with ladder and leads to following board plug type labyrinth.
5. dementia rats labyrinth type intellectual rehabilitation trainer as claimed in claim 1, it is characterized in that: described refuge pocket labyrinth is to put on the shelf at the high shelf attachment in overhead anxiety labyrinth to establish the dull and stereotyped composition of a refuge pocket, be provided with a plurality of duck eyes that penetrate platform around the refuge pocket flat board, one of them duck eye has one that ladder leads in the high shelf attachment to hide the unit.
CN2010205602813U 2010-10-14 2010-10-14 Dementia rat labyrinth type intellectual rehabilitation training device Expired - Fee Related CN201995441U (en)

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CN104221970B (en) * 2014-09-25 2016-08-24 山东省科学院生物研究所 A kind of device for studying Brachydanio rerio ability of learning and memory
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CN107047364A (en) * 2017-01-05 2017-08-18 沈阳医学院 The integrated rodent cognitive ability of multivariable towards drug law enforcement anti-terrorism examines detection ecological experiment cabin
CN110972984A (en) * 2018-10-02 2020-04-10 智能宠物家庭办公室公司 Stackable maze for small animals
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