CN201939730U - Gel nose pack for treating rosacea - Google Patents

Gel nose pack for treating rosacea Download PDF

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Publication number
CN201939730U
CN201939730U CN2011200179494U CN201120017949U CN201939730U CN 201939730 U CN201939730 U CN 201939730U CN 2011200179494 U CN2011200179494 U CN 2011200179494U CN 201120017949 U CN201120017949 U CN 201120017949U CN 201939730 U CN201939730 U CN 201939730U
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China
Prior art keywords
nose
gel
layer
pack
cover
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Expired - Fee Related
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CN2011200179494U
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Chinese (zh)
Inventor
孟永海
王锐
翟春梅
杨婧
张燕丽
杨柳
张晓娟
姜海
陈忠新
闫丽莉
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王锐
孟永海
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Priority to CN2011200179494U priority Critical patent/CN201939730U/en
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Publication of CN201939730U publication Critical patent/CN201939730U/en
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Abstract

The utility model discloses a gel nose pack for treating a rosacea, which is characterized in that the gel nose pack for treating the rosacea comprises a non-woven rubberized cloth layer, a hydrophilic high-polymer gel drug-storehouse layer and an anti-adhesion layer, wherein the non-woven rubberized cloth layer and the anti-adhesion layer are respectively adhered to both sides of the hydrophilic high-polymer gel drug-storehouse layer, a nose bridge protrusion part which can cover most part of a nose bridge is arranged at the upper end of the nose pack, a nose tip protrusion part which can cover most part of a nose tip is arranged at the lower end of the nose pack, and symmetric nose ala protrusion parts which can cover both sides of each nose ala are arranged at the left end and the right end of the nose pack. The gel nose pack for treating the rosacea has the advantages that the design is novel, and the nose pack can cover most part of an affected part of a nose of a patient; the treatment area is large, and the hydrophilic high-polymer gel drug-storehouse layer can continuously and slowly release a drug, therefore, the action time of the drug is increased, and the curative effect of the drug is improved; in addition, with the adoption of a paste form, a process of adhering and peeling is added, so that excessive oil secreted by the nose of the patient can be eliminated, and the probability of secondary mite infection is lowered; and with the adoption of a butt joint anti-adhesion layer structure which is convenient to peel in a product, the nose pack is convenient to use.

Description

The gel nose of treatment acne rosacea pastes
Technical field
Disclosed by the invention is that a kind of gel nose for the treatment of acne rosacea pastes, and is that a kind of pluralgel nose pastes.Belong to medical external patch field.
Background technology
Acne rosacea claims acarid dermatitis again, mainly is the dermatosis that betides nose and surrounding skin thereof.Be to occur in facial a kind of chronic inflammatory disease dermatoses.Normal sending out in face middle part, nose and dilator naris, the traditional Chinese medical science think, acne rosacea heat in blood, stomach-fire be it because of, stagnation of QI-blood is its reason.Some scholars think, colonize in the stimulation of the vermiform mite worm in the pilosebaceous unit, and the inflammation that its metabolite and Excreta cause is the important pathogenic factors of acne rosacea.Doctor trained in Western medicine is removed sebum to kill acarid, improves symptom for the Therapeutic Principle, uses external sulphur ointment, metronidazole ointment, Acaricides such as oral metronidazole, tinidazole more.A large amount of clinical observation confirms that short term efficacy is good really, but a drug withdrawal will rebound and increase the weight of, even also can produce side effect such as " steroid-dependent dermatitis ".
The treatment by Chinese herbs method that adopts is mainly based on the external dosage form at present, and still every kind all has its shortcoming.A kind of product (patent No. 200110040993.1) is the gel that is prepared from by the plurality of Chinese composition, need product be applied in nose affected part treatment acne rosacea with hands, uses inconvenient.Another kind of product (patent No. 200810118251.4) is a kind of medicine for external use for the treatment of acne rosacea, mainly is a kind of unguentum, also relates to hands and smears inconvenience, and do not see about treating the Chinese medicine external-use gel nose paste preparation of acne rosacea.The said goods adopts and spreads upon skin surface, drug exposure, and do not have drug storage warehouse, and drug effect can not be lasting, and therapeutic effect is affected.
Summary of the invention
The purpose of this utility model provides a kind of gel nose for the treatment of acne rosacea and pastes, to solve the problem of the inconvenient and unsatisfactory curative effect of use that prior art exists.
The technical solution of the utility model is: a kind of gel nose for the treatment of acne rosacea pastes, it is characterized in that, comprise non-woven rubberized fabric layer, hydrophilic macromolecule gel drug storehouse layer and adherent layer, at the both sides of hydrophilic macromolecule gel drug storehouse layer bonding non-woven rubberized fabric layer of difference and adherent layer; Be provided with in the upper end that this nose pastes and can cover the most bridge of the nose protuberance of the bridge of the nose, the lower end of pasting at this nose is provided with the nose protuberance that can cover nose, and the two ends, the left and right sides of pasting at this nose are provided with the symmetric wing of nose protuberance that can cover wing of nose both sides.
Described adherent layer adopts release paper or Concha Arcae film to make.
Described adherent layer is made up of two parts butt joint, is provided with overlapping limit at joint, does not establish adhesives between this overlapping limit.
Described non-woven rubberized fabric layer is made of non-woven fabrics coating medical pressure-sensitive adhesive.
The utility model has the advantages that: modern design, nose are pasted and can be covered patient's nose affected part is most of, and the treatment area is big, and the sustainable slow release of hydrophilic gel drug storehouse layer has increased action time of medicine, improves curative effect of medication.And the patch dosage form increased and pasted the process of peeling off, and can remove the excretory excess grease of patient's nose, reduces the probability that infects acarid once more.Product adopts the dock adherent layer structure of being convenient to peel off, and makes things convenient for the patient to use.
Description of drawings
Fig. 1 is the structural representation in the outside of the present utility model;
Fig. 2 is the A-A cutaway view of Fig. 1.
The specific embodiment
Referring to Fig. 1 and Fig. 2, this utility model comprises non-woven rubberized fabric layer 1, hydrophilic macromolecule gel drug storehouse layer 2 and adherent layer, at the both sides of hydrophilic macromolecule gel drug storehouse layer 2 bonding non-woven rubberized fabric layer 1 of difference and adherent layer.The upper end of pasting at this nose is provided with the bridge of the nose protuberance 6 that can cover bridge of the nose major part (the eye center line is below 1 centimetre), the lower end of pasting at this nose is provided with the nose protuberance 5 that can cover nose, and the two ends, the left and right sides of pasting at this nose are provided with the symmetric wing of nose protuberance 7 and 8 that can cover wing of nose both sides.
Described adherent layer is made up of top 3 and the butt joint of bottom 4 two parts, is provided with overlapping limit 41 at joint, does not establish adhesives between this overlapping limit 41, conveniently to open.What described adherent layer adopted is release paper or Concha Arcae film.
The coating medical pressure-sensitive adhesive is made on the described non-woven rubberized fabric layer 1 employing non-woven fabrics.
Described hydrophilic macromolecule gel drug storehouse layer 2 is by Chinese herbal medicine such as Flos Lonicerae, the Radix Stemonae, Fructus Cnidii, Radix Salviae Miltiorrhizae, Herba Centellae, Olibanum, Scorpios, obtain ointment through extracting refining and high-molecular gel carbomer, wetting agent glycerol, penetration enhancer azone fully are mixed with and form, effect with eliminating the pathogens from the lung heat clearly, blood circulation promoting and blood stasis dispelling, parasite killing detoxifcation has definite curative effect to the caused nasal disease of acarid.
The concrete prescription and the manufacture method of hydrophilic macromolecule gel drug storehouse layer 2 are as follows:
Prescription 1: with Flos Lonicerae 200g, Radix Stemonae 200g, Fructus Cnidii 150g, Radix Salviae Miltiorrhizae 150g, Herba Centellae 100g, Olibanum 50g, Scorpio 20g, adding 10 times of water gagings decocts 2 times, each 1 hour, merge decoction liquor to 1000ml, adding 95% ethanol, to contain the alcohol amount to the decoction liquor be 75%, static 24 hours, get supernatant recovery solvent and get extractum.
Take by weighing following raw material in proportion: Acritamer 940 15g, glycerol 20g, azone 10g, CMC-Na15g, triethanolamine 50g, Acritamer 940 and CMC-Na are added 1000ml water fully be swelled into gel solution, above-mentioned wetting agent glycerol, penetration enhancer azone, triethanolamine and Chinese medical concrete are sequentially added in the above-mentioned gel solution, and fully stirring and evenly mixing is coated with cream rapidly, cut off the lid lining, overlay film with the cutting of nose pattern tool, is packed existing nose and is pasted.Concrete technology is according to relevant requirements under 2010 editions gels of Pharmacopoeia of People's Republic of China and the patch item.
Prescription 2: with Flos Lonicerae 500g, Radix Stemonae 400g, Fructus Cnidii 400g, Radix Salviae Miltiorrhizae 300g, Herba Centellae 250g, Olibanum 125g, Scorpio 40g, adding 10 times of water gagings decocts 2 times, each 1 hour, merge decoction liquor to 1000ml, adding 95% ethanol, to contain the alcohol amount to the decoction liquor be 75%, static 24 hours, get supernatant recovery solvent and get extractum.
Take by weighing following raw material by prescription: Acritamer 940 20g, glycerol 20g, azone 10g, CMC-Na10g, triethanolamine 50g, Acritamer 940 and CMC-Na are added 1000ml water fully be swelled into gel solution, above-mentioned wetting agent glycerol, penetration enhancer azone, triethanolamine and Chinese medical concrete are sequentially added in the above-mentioned gel solution, and fully stirring and evenly mixing is coated with cream rapidly, cut off the lid lining, overlay film with the cutting of nose pattern tool, is packed existing nose and is pasted.Concrete technology is according to relevant requirements under 2010 editions gels of Pharmacopoeia of People's Republic of China and the patch item.
The utlity model has following characteristics:
Novel in design: in use, the bridge of the nose protuberance 6 of its upper end can cover (following 2 centimetres of eye center line) major part on the bridge of the nose; The nose protuberance 5 of its lower end can cover the big portion of nose; The wing of nose protuberance 7 at its two ends, left and right sides and 8 can cover wing of nose both sides.This design makes the site of pathological change of acne rosacea can both cover basically, has increased the treatment area, thereby has strengthened the curative effect of product.
Easy to use: because of having adopted the dock adherent layer structure of being convenient to peel off, so brought convenience to the patient.
Safety, determined curative effect: this product pure Chinese medicinal preparation, do not contain hormone, can effectively press down and kill acarid, antipruritic, anti-infection, instant effect.Adopt hydrophilic gel as substrate, strengthened the affinity of product, increased the azone penetration enhancer in the prescription, improve Transdermal absorption efficient, make medicine enter corium, thoroughly kill acarid, heighten the effect of a treatment, be difficult for recurrence in skin.

Claims (4)

1. a gel nose for the treatment of acne rosacea pastes, and it is characterized in that, comprises non-woven rubberized fabric layer, hydrophilic macromolecule gel drug storehouse layer and adherent layer, at the both sides of hydrophilic macromolecule gel drug storehouse layer bonding non-woven rubberized fabric layer of difference and adherent layer; Be provided with in the upper end that this nose pastes and can cover the most bridge of the nose protuberance of the bridge of the nose, the lower end of pasting at this nose is provided with the nose protuberance that can cover nose, and the two ends, the left and right sides of pasting at this nose are provided with the symmetric wing of nose protuberance that can cover wing of nose both sides.
2. the gel nose of treatment acne rosacea according to claim 1 pastes, and it is characterized in that, described adherent layer adopts release paper or Concha Arcae film to make.
3. the gel nose of treatment acne rosacea according to claim 1 pastes, and it is characterized in that, described adherent layer is made up of two parts butt joint, is provided with overlapping limit at joint, does not establish adhesives between this overlapping limit.
4. the gel nose of treatment acne rosacea according to claim 1 pastes, and it is characterized in that, described non-woven rubberized fabric layer is made of non-woven fabrics coating medical pressure-sensitive adhesive.
CN2011200179494U 2011-01-20 2011-01-20 Gel nose pack for treating rosacea Expired - Fee Related CN201939730U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2011200179494U CN201939730U (en) 2011-01-20 2011-01-20 Gel nose pack for treating rosacea

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Application Number Priority Date Filing Date Title
CN2011200179494U CN201939730U (en) 2011-01-20 2011-01-20 Gel nose pack for treating rosacea

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CN201939730U true CN201939730U (en) 2011-08-24

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103191184A (en) * 2013-04-16 2013-07-10 王怀伟 Novel nasal strip gel layer, novel nasal strip and preparation method of nasal strip
CN106860809A (en) * 2017-04-06 2017-06-20 中国科学院西北高原生物研究所 A kind of sweet iris flower nose patch for treating acne rosacea

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103191184A (en) * 2013-04-16 2013-07-10 王怀伟 Novel nasal strip gel layer, novel nasal strip and preparation method of nasal strip
CN106860809A (en) * 2017-04-06 2017-06-20 中国科学院西北高原生物研究所 A kind of sweet iris flower nose patch for treating acne rosacea

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C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20110824

Termination date: 20120120