CN201876418U - Immune turbidity measuring device - Google Patents
Immune turbidity measuring device Download PDFInfo
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- CN201876418U CN201876418U CN2010205941988U CN201020594198U CN201876418U CN 201876418 U CN201876418 U CN 201876418U CN 2010205941988 U CN2010205941988 U CN 2010205941988U CN 201020594198 U CN201020594198 U CN 201020594198U CN 201876418 U CN201876418 U CN 201876418U
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- light source
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- negative feedback
- feedback controller
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Abstract
The utility model discloses an immune turbidity measuring device, which comprises a light source, a photoelectric converter and a processor. The immune turbidity measuring device is characterized by further comprising a negative feedback controller and a current-to-voltage converter, an input end of the negative feedback controller is connected with an output end of the photoelectric converter, an output end of the negative feedback controller is connected with the light source, the negative feedback controller controls current of the light source to enable light intensity of the light source to be constant, an input end of the current-to-voltage converter is connected with the output end of the photoelectric converter, an output end of the current-to-voltage converter is respectively connected with an input end of the negative feedback controller and the processor, and the light source is a semiconductor light source. The immune turbidity measuring device has the advantages that the negative feedback controller is adopted to automatically adjust current flowing through the light source, and accordingly constancy of light intensity of the light source can be controlled.
Description
[technical field]
The utility model relates to the chemical analyzer field of automatic detection, specifically relates to a kind of immunoturbidimetry determinator.
[background technology]
Plasma protein composition has kind more than 1000 at least, the isolated pure product with clinical meaning have kind more than 100, wherein many albumen have specific antigenicity, can adopt the method for antigen-antibody reaction, these albumen in the samples such as blood, cerebrospinal fluid, urine are detected, so be called specific protein traditionally.These specific proteins have certain physiological function in body, have the important pathological meaning when body is in morbid state again.Kind surplus the present specific protein that has been used for clinical diagnosis reaches 40.Specific protein analyser by specialty carries out analyzing and testing to this albuminoid, can provide effective pathologic, physiologic index for clinical, and be used as the foundation of clinical diagnosis, result of treatment and analysis prognosis.
At present, immunoturbidimetry has become a kind of trace of detecting specific protein in the body fluid, has changed the routine immunization chemical analysis technology of detection fast and automatically.Its ultimate principle is: antigen-antibody forms antigen antibody complex fast in special damping fluid, make reactant liquor turbidity occur, when light passed through this turbid solution, because particle in suspension is to the selectivity absorption and the scattering process of light in the turbid solution, the light intensity of transmitted light and scattered light can change; When keeping antibody excess in the reactant liquor, the compound that forms increases with the increase of antigen amount, the turbidity of reactant liquor also increases thereupon, the light intensity variable quantity of transmitted light and scattered light and the antigen amount in the reactant liquor form certain quantitative relation, by with a series of standard control, can calculate the content of examined object.The immunoturbidimetry determinator of prior art as shown in Figure 1, the light of light source 1 is accepted by photoelectric commutator 7 by reactant liquor 5 backs of test tube 4 splendid attires, the input end of current-to-voltage convertor 9 connects the output terminal of photoelectric commutator 7, receive the current signal after changing, the output terminal of current-to-voltage convertor 9 is connected with processor 12.
There is following defective in existing immunoturbidimetry determinator: As time goes on, the luminescent device of light source is aging gradually, causes luminous light intensity to change, thereby causes the error of detection.
[summary of the invention]
The utility model provides a kind of immunoturbidimetry determinator, to solve the inconstant technical matters of light source intensity:
In order to solve the problems of the technologies described above, the utility model is by the following technical solutions: a kind of immunoturbidimetry determinator, comprise light source, photoelectric commutator and processor, also comprise the negative feedback controller, described photoelectric commutator receives the light beam that described light source sends, described processor is connected with the output terminal of described photoelectric commutator, the input end of described negative feedback controller is connected with the output terminal of described photoelectric commutator, output terminal is connected with described light source, described negative feedback controller makes the light intensity of described light source constant by the size of the electric current of the described light source of control.
Compared with prior art, the advantage of technique scheme is: the negative feedback controller can be controlled the size of current of described light source, makes the light intensity of described light source constant, thus guaranteed the immunoturbidimetry determinator testing result accurately.
The utility model also has following preferred embodiment:
Described negative feedback controller comprises amplifier, first current-limiting resistance, second current-limiting resistance and transistor; The first input end of described amplifier is connected with the output terminal of described photoelectric commutator, and second input end is connected with reference power source; Described first current-limiting resistance is coupled between the output terminal and described transistorized base stage of described amplifier, described second current-limiting resistance be coupled between described transistorized collector and the ground after light source is connected.
Also comprise current-to-voltage convertor, the input end of described current-to-voltage convertor is connected with the output terminal of described photoelectric commutator, and output terminal is connected with processor with the input end of described negative feedback controller respectively.
Further adopt current-to-voltage convertor that the current signal of described photoelectric commutator is converted to voltage signal, make and to adopt in the negative feedback controller input end to receive the amplifier of voltage signal, widened the scope of optional device greatly and reduced the realization difficulty of engineering.
The light beam of described light beam for sending through the described light source of being examined the liquid scattering.
Further adopt the advantage of above scheme to be: because in some concentration section, the variation of suspended material concentration causes scattered light intensity more obvious than the variation of transmitted light intensity, this moment, receiving scattered light was than receiving the detection sensitivity that transmitted light more helps improving instrument.
Described light source adopts semiconductor light sources, for example semiconductor laser, light emitting diode etc.
The beneficial effects of the utility model are: owing to adopted negative feedback control circuit to regulate the size of the electric current that flows through light source automatically, thereby can control the constant of light source intensity.
[description of drawings]
Fig. 1 is the immunoturbidimetry determinator figure of a kind of embodiment of the prior art;
Fig. 2 is the immunoturbidimetry determinator figure of specific embodiment of the utility model 1;
Fig. 3 is the physical circuit figure of a kind of negative feedback controller in the instantiation 1;
Fig. 4 is the immunoturbidimetry determinator figure of specific embodiment of the utility model 2;
Fig. 5 is the immunoturbidimetry determinator figure of specific embodiment of the utility model 3.
[embodiment]
Specific embodiment 1
Immunoturbidimetry determinator as shown in Figure 2 comprises light source 1, photoelectric commutator 7, negative feedback controller 11 and microprocessor (MCU) 12, and Fig. 1 also has the test tube 4 of splendid attire reactant liquor 5.Wherein light source 1 can adopt semiconductor light sources, such as emitting led, semiconductor laser etc.
Bottom the test tube of splendid attire reactant liquor, be equipped with and examined solution on a small quantity.After the light beam that semiconductor light sources 1 is sent sees through in the test tube 4 reactant liquor 5, its intensity signal is received and is converted to corresponding current signal with the coaxial mounted photoelectric commutator 7 of this bundle light, be that transmission receives, the output terminal of photoelectric commutator 7 is connected with processor 12 with the input end of negative feedback controller 11 respectively, this current signal is divided into two-way, the negative feedback controller 11 of wherein leading up to flows through the size of the electric current of semiconductor light sources 1 with negative-feedback principle control, constant to control its luminous light intensity, thereby the measuring error that realizes automatic modifying factor luminescent device to wear out and bring, another road current signal is received by processor 12, in the processor storage inside corresponding tables of size of current and examined object concentration is arranged, so processor can obtain examined object concentration according to the size of this current signal.
The physical circuit figure of negative feedback controller 11 as shown in Figure 3, In and Iref are respectively the signal input part and the reference signal input end of negative feedback controller 11, amplifier OPA, the first current-limiting resistance R1, the second current-limiting resistance R2, transistor Q, power supply VCC, semiconductor light sources 1, at present embodiment, signal input part In receives the current signal from photoelectric commutator 7, the reference signal input end receives the reference current signal, and the size of current of transistor Q is flow through in the voltage signal control of output terminal Out output.Owing to reason such as aging, the light intensity decreasing of semiconductor light sources 1, the electric current of photoelectric commutator output reduces, the output voltage of the output terminal Out of amplifier OPA reduces at this moment, thereby the electric current that flows through transistor Q is increased, so the light intensity of semiconductor light sources 1 increases, like this, promptly guaranteed light intensity constant of semiconductor light sources; In like manner, if the light intensity of semiconductor light sources 1 increases, the electric current that can cause flowing through transistor Q reduces, thereby has guaranteed light intensity constant of semiconductor light sources.Processor memory has the corresponding tables of current signal size and examined object concentration, and processor can be judged the concentration of examined object according to the size of the current signal of photoelectric commutator output.
Specific embodiment 2
Immunoturbidimetry determinator as shown in Figure 4, the difference of itself and specific embodiment 1 comprises: also comprise current-to-voltage convertor 9, the input end of current and power supply converter 9 is connected with the output terminal of photoelectric commutator 7, output terminal is connected with processor with the signal input part In of amplifier OPA respectively, in the case, what the reference signal input end Iref of amplifier OPA imported is voltage reference signal, processor memory has the corresponding tables of voltage signal size and examined object concentration, and processor can be judged the concentration of examined object according to the size of the output voltage signal of the output terminal Out of amplifier OPA.
Specific embodiment 3
Immunoturbidimetry determinator as shown in Figure 5, the difference of itself and specific embodiment 2 comprises: the light beam that imports reactant liquor after suspended material scattering wherein by with photoelectric commutator 7 receptions of the angled installation of incident direction of this bundle light and convert corresponding current signal to, be that scattering receives, this angle is relevant with the concrete solution of test.Because in some concentration section, the variation of suspended material concentration causes scattered light intensity more obvious than the variation of transmitted light intensity, this moment, receiving scattered light was than receiving the detection sensitivity that transmitted light more helps improving instrument.
The beneficial effects of the utility model are: owing to adopted the negative feedback controller to regulate the size of the electric current that flows through light source automatically, thereby can control the constant of light source intensity.
Above content be in conjunction with concrete preferred implementation to further describing that the utility model is done, can not assert that concrete enforcement of the present utility model is confined to these explanations.For the utility model person of an ordinary skill in the technical field, under the prerequisite that does not break away from the utility model design, can also make some simple deduction or replace, all should be considered as belonging to protection domain of the present utility model.
Claims (5)
1. immunoturbidimetry determinator, comprise light source, photoelectric commutator and processor, it is characterized in that, also comprise the negative feedback controller, described photoelectric commutator receives the light beam that described light source sends, and described processor is connected with the output terminal of described photoelectric commutator, the input end of described negative feedback controller is connected with the output terminal of described photoelectric commutator, output terminal is connected with described light source, and described negative feedback controller makes the light intensity of described light source constant by the size of the electric current of the described light source of control.
2. a kind of immunoturbidimetry determinator as claimed in claim 1 is characterized in that described negative feedback controller comprises amplifier, first current-limiting resistance, second current-limiting resistance and transistor; The first input end of described amplifier is connected with the output terminal of described photoelectric commutator, and second input end is connected with reference power source; Described first current-limiting resistance is coupled between the output terminal and described transistorized base stage of described amplifier, described second current-limiting resistance be coupled between described transistorized collector and the ground after light source is connected.
3. a kind of immunoturbidimetry determinator as claimed in claim 1, it is characterized in that, also comprise current-to-voltage convertor, the input end of described current-to-voltage convertor is connected with the output terminal of described photoelectric commutator, and output terminal is connected with processor with the input end of described negative feedback controller respectively.
4. a kind of immunoturbidimetry determinator as claimed in claim 1 is characterized in that, the light beam of described light beam for sending through the described light source of being examined the liquid scattering.
5. a kind of immunoturbidimetry determinator as claimed in claim 1 is characterized in that, described light source adopts semiconductor light sources.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010205941988U CN201876418U (en) | 2010-11-05 | 2010-11-05 | Immune turbidity measuring device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010205941988U CN201876418U (en) | 2010-11-05 | 2010-11-05 | Immune turbidity measuring device |
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| Publication Number | Publication Date |
|---|---|
| CN201876418U true CN201876418U (en) | 2011-06-22 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010205941988U Expired - Fee Related CN201876418U (en) | 2010-11-05 | 2010-11-05 | Immune turbidity measuring device |
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| CN (1) | CN201876418U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103344642A (en) * | 2013-07-05 | 2013-10-09 | 深圳普门科技有限公司 | Full-automatic external detection equipment and method for measuring specific egg white by turbidimetry |
| CN109855726A (en) * | 2019-01-03 | 2019-06-07 | 桂林优利特医疗电子有限公司 | A kind of calibrating installation and method of the light source power of Immune scatter turbidimetry |
-
2010
- 2010-11-05 CN CN2010205941988U patent/CN201876418U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103344642A (en) * | 2013-07-05 | 2013-10-09 | 深圳普门科技有限公司 | Full-automatic external detection equipment and method for measuring specific egg white by turbidimetry |
| CN109855726A (en) * | 2019-01-03 | 2019-06-07 | 桂林优利特医疗电子有限公司 | A kind of calibrating installation and method of the light source power of Immune scatter turbidimetry |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110622 Termination date: 20171105 |