CN201848225U - CCS granulation module system - Google Patents

CCS granulation module system Download PDF

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Publication number
CN201848225U
CN201848225U CN201020172654XU CN201020172654U CN201848225U CN 201848225 U CN201848225 U CN 201848225U CN 201020172654X U CN201020172654X U CN 201020172654XU CN 201020172654 U CN201020172654 U CN 201020172654U CN 201848225 U CN201848225 U CN 201848225U
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granulator
granulation
wet
ccs
module system
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王孟刚
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NANO PHARM TECH MACHINERY EQUIPMENT Co Ltd
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Harbin Nano Pharmaceutical & Chemical Equipment Co ltd
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Abstract

The utility model provides a CCS granulation module system. With the system, the closed production of granulation is realized by adopting the most advanced granulation process and modularized design, so that secondary pollution in the transfer process is avoided, the quality of products is improved and that the granulation process meets GMP (Good Manufacturing Practice) requirement is ensured. The CCS granulation module system consists of an efficient wet granulator, a vacuum feeding system, a boiling single-step granulator, a wet straightening granulator, a fluidized bed hopper hoister, a dry grinder, a charging barrel for turnover and the like. Through the system, the compatibility of process equipment between systems is fully considered, the rationality of the connection between processes is considered, and the continuity of the granulation production process and the stability of the production process are ensured.

Description

CCS制粒模块系统 CCS pelletizing module system

(一)技术领域(1) Technical field

本实用新型涉及的是一种密闭制粒模块系统,具体的说是一种应用于医药、食品化工等行业采用模块化制粒实现密闭连续自动化生产,避免了因转序所产生的第二次污染,保证制粒工艺符合GMP要求。 The utility model relates to an airtight granulation module system, specifically a kind of airtight granulation system used in medicine, food chemical industry and other industries to realize airtight continuous automatic production, avoiding the second Pollution, ensure that the granulation process complies with GMP requirements. the

(二)背景技术(2) Background technology

目前用于医药、食品化工等行业的制粒工艺是每台设备设置在单独的净化间内,例如湿法混合制粒机放在一个净化间,沸腾制粒机放在一个净化间,总混和整粒放在一个净化间,这样就存在物料在多个净化间内来回转序,无法避免存在的第二次污染现象,工作效率低。 The granulation process currently used in the pharmaceutical, food and chemical industries is that each equipment is set in a separate clean room, for example, the wet mixing granulator is placed in a clean room, the boiling granulator is placed in a clean room, and the total mixing The whole grain is placed in one purification room, so that there are materials going back and forth in multiple purification rooms, and the second pollution phenomenon cannot be avoided, and the work efficiency is low. the

(三)发明内容(3) Contents of the invention

本实用新型的目的在于提供一种制粒模块系统,采用封闭的输送方式连接多道工序,实现自动化生产,保证了制粒工艺在同一个净化间内完成。完全杜绝了人为的第二次污染,使制粒工艺更加符合GMP要求。 The purpose of the utility model is to provide a granulation module system, which adopts a closed conveying mode to connect multiple processes, realizes automatic production, and ensures that the granulation process is completed in the same clean room. Completely put an end to man-made secondary pollution, making the granulation process more in line with GMP requirements. the

本实用新型CCS制粒模块系统是由湿法混合制粒机、真空上料系统、沸腾制粒机、湿法整粒机、流化床料斗提升机、干法整粒机、周转用的混料桶、物料输送助推系统、中央集成控制系统等组成。真空上料系统是用管路连接到湿法混合制粒机上,原料经真空上料系统进入湿法混合制粒机,物料输送助推系统是安装在湿法整粒机的下方用密闭管路连接到沸腾制粒机上,湿法混合制粒机的出料口连接湿法整粒机,整粒好的湿颗粒通过物料输送系统用管路和沸腾制粒机的进料口连接,湿法整粒机是固定在湿法混合制粒机的出料口下方,并和输料助推系统相连接,使原料按工艺参数有序的输送到每个工序和设备,本CCS制粒模块系统是通过中央集成控制系统实现密闭自动化生产的。 The utility model CCS granulation module system is composed of a wet mixing granulator, a vacuum feeding system, a boiling granulator, a wet granulator, a fluidized bed hopper hoist, a dry granulator, and a mixing machine for turnover. It is composed of a material barrel, a material conveying booster system, and a central integrated control system. The vacuum feeding system is connected to the wet mixing granulator with pipelines, the raw materials enter the wet mixing granulator through the vacuum feeding system, and the material conveying booster system is installed under the wet granulator with a closed pipeline Connected to the boiling granulator, the outlet of the wet mixing granulator is connected to the wet granulator, and the sized wet granules are connected to the feed port of the boiling granulator through the material conveying system. The granulator is fixed under the discharge port of the wet mixing granulator, and connected with the conveying booster system, so that the raw materials are transported to each process and equipment in an orderly manner according to the process parameters. This CCS granulation module system It realizes airtight automatic production through the central integrated control system. the

本实用新型还可以包括这样的一些技术特征: The utility model can also include some technical features like this:

1、CCS制粒模块系统充分的考虑到了系统之间设备的配套性,上下工序之间工艺衔接的合理性,保证了生产工艺的连续性与生产过程的稳定性。 1. The CCS granulation module system fully considers the compatibility of the equipment between the systems and the rationality of the process connection between the upper and lower processes, ensuring the continuity of the production process and the stability of the production process. the

2、该制粒模块系统能使湿法混合制粒机与沸腾制粒机各自的特点得到充分的体现。同时采用湿法整粒机与系统组合可以保证较高的制粒成品率。 2. The granulation module system can fully reflect the respective characteristics of the wet mixing granulator and the boiling granulator. At the same time, the combination of wet granulator and system can ensure a high granulation yield. the

3、该制粒模块系统的真空上料装置、转序提升装置,具有较高的自动化程 度,从而降低了劳动强度和粉尘污染。 3. The vacuum feeding device and sequence lifting device of the granulation module system have a high degree of automation, thereby reducing labor intensity and dust pollution. the

4、通过采用中央集成控制系统,可以对湿法混合制粒机,沸腾制粒机的工艺数据通过以太网形式采集与控制。可实现在一个控制中心控制多台设备及参数设定与监控,使生产的工艺过程完全自动化,并保证工艺的稳定性。大大的节省了人力和工人的劳动强度。 4. By adopting the central integrated control system, the process data of the wet mixing granulator and the boiling granulator can be collected and controlled through Ethernet. It can realize the control of multiple devices and parameter setting and monitoring in one control center, so as to fully automate the production process and ensure the stability of the process. It greatly saves manpower and labor intensity of workers. the

本实用新型是多台不同功能设备联合组成的CCS制粒模块系统其主要目的是避免制粒过程中因物料转序所产生第二次污染。同时提高了生产效率、保证了产品质量、所有连接管路系统。与药物接触的部件能做到易拆卸、易清洗、便于生产操作和维修保养。 The utility model is a CCS granulation module system composed of a plurality of equipment with different functions. Its main purpose is to avoid the second pollution caused by material transfer during the granulation process. At the same time, the production efficiency is improved, the product quality is guaranteed, and all connecting pipeline systems are guaranteed. The parts in contact with the drug can be easily disassembled, easy to clean, and convenient for production operation and maintenance. the

(四)附图说明(4) Description of drawings

附图是CCS制粒模块系统设备工艺布置图。 The attached drawing is the equipment process layout diagram of the CCS granulation module system. the

(五)具体实施方案(5) Specific implementation plan

下面结合附图举例对实用新型作更详细的描述: The utility model is described in more detail below in conjunction with the accompanying drawings as an example:

结合图: Combined graph:

1是原料料筒,2是真空上料系统,原料经真空上料系统进入3湿法混合制粒机,加工后的湿颗粒经4湿法整粒机由10物料输送助推系统,进入5沸腾制粒机,经沸腾制粒机加工出的干燥颗粒经8流化床提升机进入7干法整粒机,经整粒加工出均匀颗粒(成品)进入6成品料筒,9是中央集成控制 1 is the raw material barrel, and 2 is the vacuum feeding system. The raw material enters the 3 wet mixing granulator through the vacuum feeding system, and the processed wet granules pass through the 4 wet granulator and the 10 material conveying booster system, and then enter the 5 Boiling granulator, the dry granules processed by the boiling granulator enter the 7 dry granulator through the 8 fluidized bed elevator, and the uniform granules (finished products) are processed into the 6 finished product barrel after granulation processing, and the 9 is the central integration control

Claims (3)

1.一种CCS制粒模块系统,它包括湿法混合制粒机、真空上料系统、沸腾制粒机、湿法整粒机、流化床料斗提升机、干法整粒机、周转用混合料桶,物料输送助推系统、中央集成控制系统;其特征是:湿法混合制粒机的出料口连接湿法整粒机,整粒好的湿颗粒通过物料输送系统用管路和沸腾制粒机的进料口连接,本CCS制粒模块系统是通过中央集成控制系统实现密闭自动化生产的。1. A CCS granulation module system, which includes a wet mixing granulator, a vacuum feeding system, a boiling granulator, a wet granulator, a fluidized bed hopper elevator, a dry granulator, and a turnover Mixing barrel, material conveying booster system, and central integrated control system; its characteristics are: the outlet of the wet mixing granulator is connected to the wet granulator, and the sized wet granules pass through the material conveying system with pipelines and The feed port of the fluidized granulator is connected, and the CCS granulation module system realizes closed automatic production through the central integrated control system. 2.根据权利要求1所述的CCS制粒模块系统,其特征是:所述的湿法整粒机是固定在湿法混合制粒机的出料口下方,并和输料助推系统相连接。2. The CCS granulation module system according to claim 1, characterized in that: the wet granulator is fixed below the outlet of the wet mixing granulator, and is connected with the feeding booster system connect. 3.根据权利要求1或2所述的CCS制粒模块系统,其特征是:真空上料系统是用管路连接到湿法混合制粒机上,原料经真空上料系统进入湿法混合制粒机,物料输送助推系统是安装在湿法整粒机的下方用密闭管路连接到沸腾制粒机上,使原料按工艺参数有序的输送到每个工序和设备。 3. The CCS granulation module system according to claim 1 or 2, characterized in that: the vacuum feeding system is connected to the wet mixing granulator with a pipeline, and the raw materials enter the wet mixing granulator through the vacuum feeding system Machine, the material conveying booster system is installed under the wet granulator and connected to the boiling granulator with a closed pipeline, so that the raw materials are transported to each process and equipment in an orderly manner according to the process parameters. the
CN201020172654XU 2010-04-28 2010-04-28 CCS granulation module system Expired - Lifetime CN201848225U (en)

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102626598A (en) * 2012-04-01 2012-08-08 江西天佳实业有限公司 Granulating unit
CN102698651A (en) * 2012-05-24 2012-10-03 浙江迦南科技股份有限公司 Wet type granulator with in-place cleaning system, and in-place cleaning method thereof
CN103157403A (en) * 2013-03-29 2013-06-19 哈尔滨纳诺机械设备有限公司 Full-automatic closed granulating line system
CN103372401A (en) * 2012-04-24 2013-10-30 都江堰市春盛中药饮片有限公司 Hydraulic lifting and granulating system
CN103505371A (en) * 2013-09-27 2014-01-15 宜春万申制药机械有限公司 Airtight dust-proof granulation, drying and granule arranging integrated pharmaceutical device
CN105423704A (en) * 2015-12-26 2016-03-23 宜春万申制药机械有限公司 Dust-free production system for granulating high-viscosity material
CN106491366A (en) * 2016-12-12 2017-03-15 宜春万申制药机械有限公司 Automatically granulation dries whole grain mixture manufacturing line to integrated form
CN106527374A (en) * 2016-12-12 2017-03-22 宜春万申制药机械有限公司 Information-based pelletizing, drying and entire granule mixed production system
CN106860016A (en) * 2017-02-08 2017-06-20 翰林航宇(天津)实业有限公司 A kind of capsule prepares all-in-one

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102626598A (en) * 2012-04-01 2012-08-08 江西天佳实业有限公司 Granulating unit
CN103372401A (en) * 2012-04-24 2013-10-30 都江堰市春盛中药饮片有限公司 Hydraulic lifting and granulating system
CN102698651B (en) * 2012-05-24 2014-05-07 浙江迦南科技股份有限公司 Wet type granulator with in-place cleaning system, and in-place cleaning method thereof
CN102698651A (en) * 2012-05-24 2012-10-03 浙江迦南科技股份有限公司 Wet type granulator with in-place cleaning system, and in-place cleaning method thereof
CN103157403A (en) * 2013-03-29 2013-06-19 哈尔滨纳诺机械设备有限公司 Full-automatic closed granulating line system
CN103505371B (en) * 2013-09-27 2015-03-04 宜春万申制药机械有限公司 Airtight dust-proof granulation, drying and granule arranging integrated pharmaceutical device
CN103505371A (en) * 2013-09-27 2014-01-15 宜春万申制药机械有限公司 Airtight dust-proof granulation, drying and granule arranging integrated pharmaceutical device
CN105423704A (en) * 2015-12-26 2016-03-23 宜春万申制药机械有限公司 Dust-free production system for granulating high-viscosity material
WO2017107836A1 (en) * 2015-12-26 2017-06-29 宜春万申制药机械有限公司 Hopper washing drying system
CN105423704B (en) * 2015-12-26 2019-01-22 宜春万申制药机械有限公司 High-viscosity material granulation dust-free production system
CN106491366A (en) * 2016-12-12 2017-03-15 宜春万申制药机械有限公司 Automatically granulation dries whole grain mixture manufacturing line to integrated form
CN106527374A (en) * 2016-12-12 2017-03-22 宜春万申制药机械有限公司 Information-based pelletizing, drying and entire granule mixed production system
WO2018108045A1 (en) * 2016-12-12 2018-06-21 宜春万申制药机械有限公司 Integrated-type fully automated pelletizing, drying and granulating mixed production line
CN106860016A (en) * 2017-02-08 2017-06-20 翰林航宇(天津)实业有限公司 A kind of capsule prepares all-in-one

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Legal Events

Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
EE01 Entry into force of recordation of patent licensing contract

Assignee: Nano Pharm Tech Machinery Equipment Co., Ltd.

Assignor: Harbin Nano Pharmaceutical & Chemical Equipment Co.,Ltd.

Contract record no.: 2013230001796

Denomination of utility model: CCS granulation module system

Granted publication date: 20110601

License type: Exclusive License

Record date: 20130918

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Owner name: NANO PHARM TECH MACHINERY EQUIPMENT CO., LTD.

Free format text: FORMER OWNER: HARBIN NANO PHARMACEUTICAL + CHEMICAL EQUIPMENT CO., LTD.

Effective date: 20141104

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Effective date of registration: 20141104

Address after: 150086, Heilongjiang Harbin hi tech Zone Yingbin Road Central District, South Dianchi road and Yimeng road junction

Patentee after: Nano Pharm Tech Machinery Equipment Co., Ltd.

Address before: 150086 No. 58 cable street, Xuefu Road, Nangang District, Heilongjiang, Harbin

Patentee before: Harbin Nano Pharmaceutical & Chemical Equipment Co.,Ltd.