CN201799013U - Intracavitary visible photodynamic therapeutic instrument - Google Patents

Intracavitary visible photodynamic therapeutic instrument Download PDF

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Publication number
CN201799013U
CN201799013U CN2010205218217U CN201020521821U CN201799013U CN 201799013 U CN201799013 U CN 201799013U CN 2010205218217 U CN2010205218217 U CN 2010205218217U CN 201020521821 U CN201020521821 U CN 201020521821U CN 201799013 U CN201799013 U CN 201799013U
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CN
China
Prior art keywords
endoscope
light source
laser
instrument
laser light
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Expired - Fee Related
Application number
CN2010205218217U
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Chinese (zh)
Inventor
文宇
熊力
谭迪熬
彭世文
苗雄鹰
喻灿球
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Central South University
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Central South University
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Priority to CN2010205218217U priority Critical patent/CN201799013U/en
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Publication of CN201799013U publication Critical patent/CN201799013U/en
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Expired - Fee Related legal-status Critical Current

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Abstract

The utility model provides an intracavitary visible photodynamic therapeutic instrument. The instrument comprises an endoscope or inner endoscope, a laser light source and a laser conductive fiber, wherein one end of the laser conductive fiber is arranged in a cold light source channel of the endoscope, while the other end is connected with the laser light source; the endoscope or inner endoscope is one of a laparoscope, a joint endoscope, a thoracoscope or neuroendoscope, a gastroscope, a cystoscope and the like. The instrument realizes visible lighting in a body cavity by using the endoscope or inner endoscope, and introduces the laser light source to the lesion location in the body cavity so as to provide clear view for implementing gross resection surgeries, radiate by laser, and increase time for killing tumor cells. Furthermore, the instrument has small toxic or side effect, overcomes the defects of local cancer tissue invasion, lymph node metastasis, hematogenous metastasis, tumor cell detachment and implantation and the like which cannot be solved by chemotherapy, radiotherapy and other means. Based on application of photosensitizer, the actual range of a malignant lesions can be displayed, and 'target lesion' can be treated actively. The instrument has reasonable and simple structure, and can provide visible lighting in the body cavity to implement effective treatment on the 'target lesion'.

Description

Intracavitary visible photodynamic therapeutic instrument
Technical field
The utility model discloses a kind of intracavity (abdominal cavity, thoracic cavity, articular cavity etc.) visible photodynamic therapeutic instrument, belong to technical field of medical instruments.
Background technology
Optical dynamic therapy is the method for the multiple malignant tumor of treatment (comprising various intracavitary neoplasms).The principle of photodynamic effect is a kind of by laser induced photochemical reaction.Photodynamic therapy is to utilize photosensitizer to be absorbed in a large number by cancerous tissue, and the very few characteristics that absorb of normal structure, the special laser irradiation cancerous protuberance of reuse, cancerous cell is destroyed and dead.Photosensitizer can selectivity accumulates, killing tumor cell specifically, and little to the health tissues infringement, toxicity is little, and favorable repeatability so optical dynamic therapy is very suitable for oldaged physically weak, can not performs the operation or the patient of intravenous chemotherapy, so more and more comes into one's own.
Because photodynamic therapy is a kind of topical therapeutic, the fragmentation effect of tumor is decided by to a great extent whether the illuminating dose of diseased region is abundant.Therefore, optical dynamic therapy must closely shine directly into patient part with the energy of laser, utilizes the combined effect of laser energy and photosensitizer, reaches the purpose of killing and wounding pathological tissues; Present photodynamic therapeutic instrument is mainly used in the position that patient part can observe directly, as diseases such as superficial tumor, dermatosis and infection.And for occurring in the body cavity, the sufferer as positions such as abdominal cavity, thoracic cavity, articular cavity, cranial cavities does not then possess the execution condition; This mainly is owing to the parcel of body wall (stomach wall, thoracic wall, joint capsule, skull etc.) stereome outside the chamber, makes the pathological changes of intracavity exist deeply, is in dark state; And existing photodynamic therapeutic instrument is because the defective that structural design exists, illumination and visual function can't be provided, therefore, even adopting the mode of Minimally Invasive Surgery delivers to the laser of photodynamic therapeutic instrument in the body cavity, also can't search out the accurate position of pathological tissues or organ, can't implement effectively treatment to pathological tissues or organ, even may cause damage normal structure or organ.
Along with industrial improvement of Manufacturing Technology, being fused to of related discipline carried out endoscope-assistant surgery and established solid foundation.The basic procedure of endoscope-assistant surgery is to use cold light source that illumination is provided, the image that utilization digital camera technology arrives lens shooting, conduct to signal processing system and be presented on the monitor in real time by optical fibers, the doctor carries out analytical judgment by shown image on the monitor screen to patient's state of an illness then, and the utilization special instrument undergos surgery.The chamber mirror that uses in the endoscope-assistant surgery can effectively provide endoceliac visual illumination, but the chamber mirror itself does not have the function of treatment or operation, must use special instrument to carry out treatment initiatively to target " target focus ".That is to say, must special instrument be delivered in " target focus " residing body cavity that could implement operative treatment, this can increase the wound to patient's body undoubtedly by other approach.
The utility model content
The purpose of this utility model is to overcome the deficiency of prior art and provides a kind of simple and reasonable, and endoceliac real-time visual illumination both can be provided, and can implement the effectively intracavitary visible photodynamic therapeutic instrument of treatment to " target focus " again.
This utility model intracavitary visible photodynamic therapeutic instrument is to adopt following proposal to realize: intracavitary visible photodynamic therapeutic instrument, comprise chamber mirror, LASER Light Source, laser conduction optical fiber, one end of described laser conduction optical fiber is arranged in the cold light source passage of described chamber mirror, and the other end links to each other with LASER Light Source.
In this utility model, described chamber mirror is a kind of in peritoneoscope, articular cavity mirror, thoracoscope or nerve endoscope, gastroscope, the cystoscope.
This utility model is owing to adopt said structure, utilize the chamber mirror to realize to endoceliac visual illumination, simultaneously LASER Light Source is imported to diseased region in the body cavity, both can provide and implement the clear visual field of resection operation substantially, simultaneously, can carry out laser irradiation, increase the time of killing tumor cell, and toxic and side effects is little, has overcome by all indeterminable local cancerous tissue infiltration of means such as chemotherapy, radiotherapy, lymphatic metastasis, hematogenous metastasis, the tumor cell problems such as plantation that come off.
This utility model not only can be used for providing the visual field in abdominal cavity, pelvic cavity, thoracic cavity etc., also the light power light source that plays therapeutical effect can be imported abdominal cavity, pelvic cavity, thoracic cavity etc., meets clinical needs.This utility model enters in the body cavity light power light source by existing chamber lens head, when light power light source is provided, can also provide art open country clearly.
Use this utility model, utilize the characteristics of the special absorption photosensitizer of tumor tissues energy, adopt with the respective wavelength laser-induced fluorescence (LIF) of photosensitizer coupling and carry out medical diagnosis, can be used for diagnosing tumor, labelling in the auxiliary art, clear and definite excision extension.Therefore,, not only can reach purpose, can also demonstrate the true scope of pernicious focus, make the clinician purpose be arranged, targetedly carry out treatment initiatively at " target focus " except that the tumor irradiation based on using photosensitizer.
This utility model light source is by chamber lens head input body cavity.Unite two into one by light source and chamber mirror light-source system the light dynamical system, the patient can operation process in, Yi Bian carry out surgery operating removing tumor, Yi Bian carry out optical dynamic therapy.Use this utility model, make OPK light source import no longer difficulty, and illumination range only is confined to endoscope-assistant surgery zone (diseased region), side reaction is littler.The more important thing is that along with excision cardinal principle tumor, the OPK treatment degree of depth is also progressively deepened, tumor cell that come off, that may plant transfer is also killed by the light power mechanism in the art simultaneously, and the effect of operation is strengthened greatly, really reaches radical cure.
This utility model is based on the combination of chamber mirror surgery, photodynamic therapy, and indication is wide, is suitable for the ancillary method as operative treatment, and what still play never only is assosting effect, might improve whole radical cure effect.
Description of drawings
Accompanying drawing 1 is this utility model structural representation.
In the accompanying drawing: 1-chamber mirror, 2-LASER Light Source, 3-laser conduction optical fiber.
The specific embodiment
Below in conjunction with specific embodiment, this utility model is described in further details.
Referring to accompanying drawing, this utility model intracavitary visible photodynamic therapeutic instrument comprises chamber mirror 1, LASER Light Source 2, laser conduction optical fiber 3, is provided with lens 4, cold light source transmission line 5 in the described chamber mirror 1; One end of described laser conduction optical fiber 3 is arranged in the cold light source passage 4 of described chamber mirror 1, and the other end links to each other with LASER Light Source 2.
In the present embodiment, described chamber mirror 1 is a peritoneoscope.
When present embodiment uses, adopt Minimally Invasive Surgery on patient body, to cut out an aperture, then, present embodiment is inserted in the patient's body lumen by described aperture, connect the peritoneoscope cold light source, to throwing light in the body cavity, by the endoceliac situation of laparoscopic visualization, search out " target focus " after, restart LASER Light Source 2, laser carries out directly effectively active treatment by laser conduction optical fiber 3 to " target focus ", can cooperate other treatments such as operation simultaneously.

Claims (2)

1. intracavitary visible photodynamic therapeutic instrument comprises chamber mirror or scope, LASER Light Source, laser conduction optical fiber, and it is characterized in that: an end of described laser conduction optical fiber is arranged in the cold light source passage of described chamber mirror or scope, and the other end links to each other with LASER Light Source.
2. intracavitary visible photodynamic therapeutic instrument according to claim 1 is characterized in that: described chamber mirror or a kind of in peritoneoscope, articular cavity mirror, thoracoscope or nerve endoscope, gastroscope, the cystoscope.
CN2010205218217U 2010-09-08 2010-09-08 Intracavitary visible photodynamic therapeutic instrument Expired - Fee Related CN201799013U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2010205218217U CN201799013U (en) 2010-09-08 2010-09-08 Intracavitary visible photodynamic therapeutic instrument

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2010205218217U CN201799013U (en) 2010-09-08 2010-09-08 Intracavitary visible photodynamic therapeutic instrument

Publications (1)

Publication Number Publication Date
CN201799013U true CN201799013U (en) 2011-04-20

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101920072A (en) * 2010-09-08 2010-12-22 中南大学 Intracavitary visible photodynamic therapeutic instrument
CN107626046A (en) * 2017-10-27 2018-01-26 贵阳中医学院 Phototherapeutic device and method for perifolliculitis capitis abscedens et suffodiens

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101920072A (en) * 2010-09-08 2010-12-22 中南大学 Intracavitary visible photodynamic therapeutic instrument
CN107626046A (en) * 2017-10-27 2018-01-26 贵阳中医学院 Phototherapeutic device and method for perifolliculitis capitis abscedens et suffodiens

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20110420

Termination date: 20140908

EXPY Termination of patent right or utility model