KR101876807B1 - Photo dynamics apparatus for medical treatment or needle - Google Patents

Abstract

The present invention relates to a medical photodynamic therapy device, and more particularly, A position adjuster capable of sliding or fixing the base portion; A moving unit capable of moving from the fixed position to the position adjusting unit; A flexible hose extending at a predetermined length at a front end of the base portion; And a needle embedded in the flexible hose and protruding outward by a predetermined length according to the movement of the moving part, wherein the needle is made of a transparent material, and the end part is sealed with the transparent material, As the fibers are embedded in the sealed state inside the needle, they are not exposed to the outside, and the laser light generated from the optical fibers is irradiated to the outside through the transparent needle.

Description

[0001] The present invention relates to a photodynamic therapy apparatus,

The present invention relates to a medical photodynamic therapy apparatus, and more particularly, to a photodynamic therapy apparatus for medical use that protects an optical fiber that destroys a tumor tissue by generating laser light to cause a tumor treatment, Treatment device.

In recent years, endoscopes have been becoming popular in which an instrument or a machine is inserted and observed for organs that can not directly see a lesion without surgery or autopsy due to the development of science technology and medical technology.

Types of endoscopy include bronchoscopy, esophagus, stomach, duodenal, rectal, bladder, and laparoscopic. Other special cases include thoracoscopic, mediastinal, and cardiac.

In the endoscope, a single tube is used as an endoscope, and the endoscope can be directly seen by the naked eye, a mold using a lens system, a type in which a camera is directly inserted into an organ such as the upper camera, and a fiber scope using glass fiber have.

Laparoscopic long-term surgery, which is a kind of endoscopy, is performed by cutting the abdomen 0.5 ~ 1 cm, puncturing 3-4 holes, inserting the laparoscope into the abdominal cavity, Is a surgical method to treat.

This laparoscopic operation is applied to the resection, biliary stone removal, abdominal stones removal, appendectomy, and various long-term tumor resection operations. There are fewer complications such as pain in the postoperative period, fewer complications such as intussusception, The recovery period is 3-4 days shorter than that of the open surgery, but it has been recently performed because of the advantage of only small scars.

In particular, in order to overcome problems such as loss of normal tissue due to surgical laparotomy, severe side effects caused by chemotherapy, and limitation of the number of investigations by radiotherapy in the treatment of malignant tumor (cancer) Photodynamic Therapy (PDT) therapy has been proposed recently and is widely used.

Photodynamic therapy is a new method of treating tumors using oxygen in the human body, an externally supplied laser, and a photosensitizing agent that reacts sensitively to laser light. The principle of this photodynamic therapy is that, after administration of a photosensitizer to a patient, When a certain period of time elapses, the photosensitizer selectively accumulates in the tumor tissue. By irradiating laser light of a specific wavelength matching the photosensitizer agent, the normal tissue that generates singlet oxygen is selectively necrosed without damaging the tumor tissue .

For such photodynamic therapy, the patient is induced to sleep or sedated, and the tumor tissue is then irradiated with laser light to necrotize the tumor tissue.

Therefore, in the conventional medical photodynamic therapy apparatus, the optical fiber for generating the laser beam directly penetrates into the tumor of the human body. In this case, the optical fiber or the therapeutic probe (hereinafter referred to as the optical fiber) There is a problem in that the laser light can not be irradiated properly because there is no room for contamination or light transmission due to direct contact, resulting in poor therapeutic effect.

In addition, the optical fibers are formed to be very thin. When the optical fibers are finally infiltrated into the tumor tissue, they may be bent or broken by the frictional resistance, .

In addition, there is a problem in that the optical fiber directly contacts the tumor and there is no space for irradiating the laser beam, so that separate irradiation is insufficient.

Korean Patent Registration No. 1531646 (June 19, 2015) Korean Utility Model Registration No. 0441715 (2008.08.28.)

Disclosure of Invention Technical Problem [8] Accordingly, the present invention has been made keeping in mind the above problems occurring in the prior art, and an object of the present invention is to provide a medical treatment method, And to provide a photodynamic therapy apparatus.

It is another object of the present invention to provide a medical photodynamic therapy device capable of maximizing the tumor treatment effect by providing a direct space for irradiating laser light.

The problems of the present invention are not limited to the above-mentioned problems, and other problems not mentioned can be clearly understood by those skilled in the art from the following description.

According to an aspect of the present invention, there is provided a medical optical therapy apparatus comprising: a base portion having a dimension on a surface thereof; A position adjuster capable of sliding or fixing the base portion; A moving unit capable of moving from the fixed position to the position adjusting unit; A flexible hose extending at a predetermined length at a front end of the base portion; And a needle embedded in the flexible hose and protruding outward by a predetermined length according to the movement of the moving part, wherein the needle is made of a transparent material, and the end part is sealed with the transparent material, As the fibers are embedded in the sealed state inside the needles, they are not exposed to the outside, and the laser light generated from the optical fibers can be irradiated to the outside through the transparent needle.

Here, the needle may be made of any one of a reinforced glass material of flexible crystal sapphire, a general tempered glass material, and a reinforced plastic material.

The distal end of the needle may be formed in any one of a sharp shape in which one side is sharp, a central portion is sharp, or rounded.

The needle is composed of a first needle portion made of a transparent material having a length in which the optical fiber is embedded and a second needle portion made of a soft iron for a length in which the optical fiber is not buried, And the second needle portion may be combined.

The tips of the needles may be inclined at an angle of 30 to 90 degrees in a direction perpendicular to the horizontal direction.

Other specific details of the invention are included in the detailed description and drawings.

According to the medical photodynamic therapy apparatus according to the embodiment of the present invention, since the optical fiber is not in direct contact with the tumor tissue, there is no fear of contamination or damage of the optical fiber, and the effect of treating the tumor can be maximized .

In addition, according to the medical photodynamic therapy apparatus according to the embodiment of the present invention, a direct space for irradiating the laser beam can be provided, thereby maximizing the tumor treatment effect.

The effects according to the present invention are not limited by the contents exemplified above, and more various effects are included in the specification.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is an overall perspective view of a conventional medical photodynamic therapy device. FIG.
2 is an enlarged perspective view of an end portion of the flexible hose in FIG.
FIG. 3 is a perspective view showing a state in which the needle protrudes through the end of the flexible hose in FIG. 2; FIG.
FIG. 4 is a perspective view showing a state in which optical fibers protrude through an end of the needle in FIG. 3; FIG.
5 is a sectional view of FIG. 2;
6 is a sectional view of Fig. 3;
Fig. 7 is a sectional view of Fig. 4; Fig.
FIG. 8 is a perspective view showing a state in which a transparent needle having optical fibers embedded through an end of a flexible hose is protruded in a medical treatment apparatus for medical treatment according to an embodiment of the present invention. FIG.
Fig. 9 is a sectional view of Fig. 8; Fig.
10 is a cross-sectional view schematically showing a process of treating tumor tissue using a medical photodynamic therapy apparatus according to an embodiment of the present invention.
11 and 12 are cross-sectional views showing another embodiment of a medical photodynamic therapy apparatus according to an embodiment of the present invention.

BRIEF DESCRIPTION OF THE DRAWINGS The advantages and features of the present invention, and the manner of achieving them, will be apparent from and elucidated with reference to the embodiments described hereinafter in conjunction with the accompanying drawings. The present invention may, however, be embodied in many different forms and should not be construed as being limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art. Is provided to fully convey the scope of the invention to those skilled in the art, and the invention is only defined by the scope of the claims. Like reference numerals refer to like elements throughout the specification.

Thus, in some embodiments, well known process steps, well-known structures, and well-known techniques are not specifically described to avoid an undue interpretation of the present invention.

The terminology used herein is for the purpose of illustrating embodiments and is not intended to be limiting of the present invention. In the present specification, the singular form includes plural forms unless otherwise specified in the specification. It should be understood that the terms comprising and / or comprising the terms used in the specification do not exclude the presence or addition of one or more other components, steps and / or operations other than the stated components, steps and / . And "and / or" include each and any combination of one or more of the mentioned items.

Further, the embodiments described herein will be described with reference to the perspective view, cross-sectional view, side view, and / or schematic views, which are ideal illustrations of the present invention. Thus, the shape of the illustrations may be modified by manufacturing techniques and / or tolerances. Therefore, the embodiments of the present invention are not limited to the specific forms shown, but also include changes in the forms generated according to the manufacturing process. In addition, in the respective drawings shown in the embodiments of the present invention, the respective constituent elements may be somewhat enlarged or reduced in view of convenience of description.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, preferred embodiments of a medical photodynamic therapy apparatus according to the present invention will be described in detail with reference to the accompanying drawings.

First, prior to describing a medical photodynamic therapy apparatus according to an embodiment of the present invention, a conventional medical photodynamic therapy apparatus will be described.

2 is an enlarged perspective view of an end portion of the flexible hose in FIG. 1, and FIG. 3 is a perspective view showing a state in which the needle is protruded through the end portion of the flexible hose in FIG. And FIG. 4 is a perspective view showing a state in which optical fibers protrude through the ends of the needles in FIG.

5 is a sectional view of Fig. 2, Fig. 6 is a sectional view of Fig. 3, and Fig. 7 is a sectional view of Fig.

As shown in the drawing, a conventional medical optical therapy apparatus 100 includes a base 110 having a dimension at a predetermined interval on one surface thereof, a position capable of sliding and fixing with respect to the base 110, And a moving unit 130 capable of moving to the position adjusting unit 120 in a state where the position adjusting unit is fixed to the base unit 110. [

A flexible hose 140 formed to extend at a predetermined length from the tip of the base 110 and a needle 200 accommodated through an opening hole 142 formed at an end of the flexible hose 140, And an optical fiber 300, which is also accommodated through the opening hole 210 of the optical fiber 200.

And a pressing unit 150 provided at a rear end of the moving unit 130 to project the optical fibers 300 from the needles 200.

Here, the position adjusting part 120 is slidable along the base part 110 and can be moved or fixed, and a through hole is formed on one surface thereof. Thus, a dimension displayed on the surface of the base part 110 through the through hole Is exposed to the outside.

A fixing screw 122 is rotatably disposed at one end of the position adjusting unit 120 so that when the fixing screw 122 is tightened, the position adjusting unit 120 is slid with respect to the base 110 And when the fixing screw 122 is loosened, the position adjusting unit 120 is slidable with respect to the base unit 110.

The dimensions displayed on one side of the base 110 may be Arabic numerals. For example, it may be an Arabic number such as 1,2,3,4,5 .., and the unit may be cm.

Meanwhile, the flexible hose 140 is provided with a flexible feature so that it can flex freely. In this case, the flexible hose 140 is made of a soft metal so as not to have an elastic restoring force for restoring the bent state to a circular state .

The operation of the conventional medical optical therapy apparatus 100 constructed as described above will be described below.

The practitioner, who may be a doctor, usually inserts a flexible hose 140 of a certain length toward the affected part of the patient, i.e., the tumor.

When the end of the flexible hose 140 reaches the tumor of the patient, the operator slides the position adjuster 120 to the selected dimension of the base 110 in accordance with the protrusion distance of the needle 200 to be inserted into the tumor, .

For example, if the practitioner wishes the needle 200 to protrude 3 cm from the end of the flexible hose 140, the position adjuster 120 is slid to the position 3 indicated on one side of the base 110 The fixing screw 122 is tightened and then the moving part 130 is pushed to the position adjusting part 120. As shown in FIGS. 3 and 6, when the moving part 130 is moved by 3 cm from the end of the flexible hose 140 The needle 200 protrudes.

At this time, since the tip of the needle 200 is inclined in one direction and the tip is sharp, the tumor to be treated is easily inserted and inserted.

In this state, when the practitioner pushes the pusher 150 toward the moving part 130, the optical fibers 300 protrude from the end of the needle 200, as shown in FIGS.

Thus, when the optical fiber 300 is penetrated into the tumor, the optical fiber 300 irradiates the laser beam according to the light generation signal, and the irradiated laser beam reacts with the previously administered optical sensitizer to destroy the tumor The treatment of the tumor is made.

In this case, the optical fiber 300 is disposed inside the opening hole 210 of the needle 200 and protrudes outward when the pressing part 150 is pressed, so that when the needle 200 penetrates and infiltrates the tumor A part of the tumor tissue and a blood stain may flow into the inside through the opening hole 210 of the needle 200. This may cause the opening hole 210 of the needle 200 to be clogged, 300 may not protrude properly.

Further, when the optical fiber 300 penetrates into the tumor tissue and is inserted, damage may occur, such as warping or breaking, due to frictional resistance with the tumor tissue.

That is, the diameter of the needle 200 is very small, and accordingly, the diameter of the opening hole 210 of the needle 200 is also very small. The tumor tissue, blood stain and the like are scattered through the opening hole 210 of the small needle 200 The optical fibers 300 are less likely to protrude and the optical fibers 300 have a diameter smaller than that of the needles 200 so that the optical fibers 300 are easily bent by the frictional resistance when protruding from the needles 200 There is a great fear of damage such as breakage.

As described above, when the optical fiber 300 is contaminated or damaged, the laser beam can not be properly irradiated, and thus the effect of the tumor treatment may be lowered.

FIG. 8 is a perspective view showing a state in which a transparent needle having an optical fiber embedded therein is protruded through an end of a flexible hose in a medical treatment apparatus for medical treatment according to an embodiment of the present invention, FIG. 9 is a sectional view of FIG. 8, 10 is a cross-sectional view schematically showing a process of treating tumor tissue using a medical photodynamic therapy apparatus according to an embodiment of the present invention.

In the following description of the medical photodynamic therapy device according to the embodiment of the present invention, the same parts as those of the conventional medical photodynamic therapy device described above are denoted by the same reference numerals, and a repeated description thereof will be omitted .

Referring to FIGS. 8 and 9, the needle 500 in the medical photodynamic therapy apparatus according to the embodiment of the present invention is located in the flexible hose 140, and the operator moves the moving part to the outside Can be protruded.

Since its operation is the same as that described above, a repetitive description thereof will be omitted.

However, the needle 500 applied to the medical optical therapy apparatus according to the embodiment of the present invention may have a shielded shape without forming an opening hole at the tip.

Here, the needle 500 may be made of a flexible tempered glass material, a general tempered glass material, or a reinforced plastic material rather than a metal material, and the needle 500 may have a transparent characteristic. The needle 500 preferably has a diameter of 19 to 21G But is not limited thereto, and the diameter of the needle 500 may be somewhat variable.

As described above, when the material of the needle 500 is tempered glass, it may preferably be a crystal sapphire.

As described above, the transparent needle 500 having the shielded tip may be fabricated with the optical fiber 600 embedded therein. That is, the needles are made of a transparent material, and the ends are sealed with the transparent material.

That is, a receiving space having a predetermined diameter may be formed inside the needle 500, and the optical fiber 600 may be embedded in the receiving space.

However, since the length of the needle 500 is only as long as the length of the optical fiber 600 embedded therein, the remaining length of the needle 500, in which the optical fiber 600 is not embedded, May be applied to those made of soft iron.

That is, a first needle portion made of a transparent material is formed as long as the length of the optical fiber 600 is embedded in the entire length of the needle 500, and a second needle portion made of a soft iron And may be connected to each other by forming needle portions.

The operation of the medical optical therapy apparatus according to the embodiment of the present invention having the above-described structure will be described as follows.

The practitioner, who may be a doctor, typically inserts the flexible hose 140 toward the affected part of the patient, i.e., the tumor.

When the end of the flexible hose 140 reaches the patient's tumor, the operator slides and moves the position adjuster to the selected dimension of the base portion in accordance with the projection distance of the needle 500 having the transparent characteristic to be inserted into the tumor.

For example, if the practitioner wishes the needle 500 to protrude 3 cm from the end of the flexible hose 140, the position adjuster is slid to the position 3 indicated on one side of the base, When the next moving part is pushed to the position adjusting part, the needle 500 protrudes by 3 cm from the end of the flexible hose 140, as shown in Figs. 8 to 10.

At this time, since the tip of the needle 500 is formed to be inclined in one direction and has a sharp tip, the tumor to be treated can be easily inserted and inserted. In this case, Since the optical fiber 600 is buried, the optical fiber 600 is also located inside the tumor.

At this time, since the optical fiber 600 is embedded in the needle 500 and is not exposed to the outside, the optical fiber 600 penetrates into the tumor when the needle 500 protrudes, And the blood does not come into direct contact with the tissue or blood.

In this state, when the optical fiber 600 is irradiated with the laser light, the irradiated laser light is transmitted through the needle 500 of transparent material into the tumor as shown in FIG. 10, By reacting with the administered photosensitizer, the tumor is necrotized and the tumor is treated.

As described above, when the needle 500 is inserted through the tumor, the optical fiber 600 is not subjected to the frictional resistance due to the tumor tissue or the like, so that there is no fear of bending or breaking, As a result, direct contact with tumor tissue can not be achieved and the fear of contamination can be dispelled.

For example, in the medical photodynamic therapy apparatus according to the embodiment of the present invention, the distal end of the needle 500 made of a transparent material is inclined so as to have a pointed shape. However, this is merely an example, The inclination angle of the leading end of the light source 500 may range from 30 to 90 degrees.

That is, the inclination angle in the direction perpendicular to the horizontal direction at the tip of the needle 500 may range from 30 to 90 degrees.

For example, as shown in FIG. 11, the tip of the needle 500 may have a sharp center, or may be rounded as shown in FIG.

The medical optical therapy apparatus according to the embodiment of the present invention maintains the optical fiber 600 embedded in the inner receiving space of the needle 500 so that the optical fiber 600 penetrates the tumor tissue, And only the needles 500 need to be inserted through the tumor tissue. Therefore, the tip of the needle 500 may not be sharpened but may be formed to be 90 degrees thick.

In other words, conventionally, after the needle 500 has penetrated the tumor tissue, the fine-diameter optical fiber 600 has to be inserted into the tumor tissue through the opened part, so that the tip of the needle 500 is sharpened, However, in the case of the medical photodynamic therapy apparatus according to the embodiment of the present invention, as described above, the optical fiber 600 is embedded in the needle 500, The inclination angle of the distal end of the needle 500 may be formed to be close to 90 degrees so as to be formed thickly as long as it can be inserted through the tumor tissue.

In this way, when the tip of the needle 500 is formed thickly, it can be easily applied to an open space such as a vagina, a cervix, or the like.

It will be understood by those skilled in the art that the present invention may be embodied in other specific forms without departing from the spirit or essential characteristics thereof. It is therefore to be understood that the above-described embodiments are illustrative in all aspects and not restrictive. The scope of the present invention is defined by the appended claims rather than the detailed description and all changes or modifications derived from the meaning and scope of the claims and their equivalents are to be construed as being included within the scope of the present invention do.

100: photodynamic therapy device 110: base part
120: position adjusting section 130: moving section
140: Flexible hose 150: Needle
600: Optical fiber

Claims (5)

A moving part capable of moving to the position adjusting part in a state in which the position adjusting part is fixed, and a moving part capable of moving from the base part to the base part, And a needle embedded in the flexible hose and protruding outward by a predetermined length in accordance with the movement of the moving part, the medical optical therapy apparatus comprising:
Wherein the needle is made of a transparent material, the end portion is sealed with the transparent material,
Since the optical fiber for irradiating the laser beam is embedded in the sealed state inside the needle, it is not exposed to the outside, and the laser beam generated from the optical fiber is irradiated to the outside through the transparent needle,
The tips of the needles are formed in a round shape so as to form a flat shape,
And a first needle portion made of a transparent material having a length in which the optical fiber is embedded,
And a second needle portion made of soft iron as long as the length in which the optical fiber is not buried,
Wherein the first needle portion and the second needle portion are coupled to each other.
The method according to claim 1,
Wherein the needle is made of any one of a reinforced glass material of flexible crystal sapphire, a general tempered glass material, and a reinforced plastic material.
delete delete The method according to claim 1,
The tip of the needle
And an inclination angle in the vertical direction with respect to the horizontal direction is 30 to 90 degrees.

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