CN201785381U - Foldable hybridization box - Google Patents
Foldable hybridization box Download PDFInfo
- Publication number
- CN201785381U CN201785381U CN2010201609194U CN201020160919U CN201785381U CN 201785381 U CN201785381 U CN 201785381U CN 2010201609194 U CN2010201609194 U CN 2010201609194U CN 201020160919 U CN201020160919 U CN 201020160919U CN 201785381 U CN201785381 U CN 201785381U
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- CN
- China
- Prior art keywords
- hybridization
- lower cover
- chip
- box
- cover plate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model belongs to the field of biological chip operation equipment, and particularly relates to a foldable hybridization box, which consists of an upper box (1) and a lower box (3). The upper cover (1) is connected with the lower cover (3) through a connecting shaft (4), a fixed cover plate (2) is connected between the upper cover (1) and the lower cover (3) via the connecting shaft (4), sealing adhesive strips (5) are disposed at edges of the inner sides of the upper cover (1) and the lower cover (3), and a chip groove (6) is arranged on the fixed cover plate (2) and provided with a sample adding hole (7). The foldable hybridization box is a closed system isolated from the external environment, thereby preventing chip hybridization liquid from being volatilized, providing stable and uniform reaction conditions for hybridization incubation of gene microarray chips, greatly reducing result coefficient of variation, and obviously increasing signal to noise ratio of chip hybridization.
Description
Technical field: the utility model belongs to biochip operating equipment field, specifically is a kind of collapsible hybridizing box.
Background technology: the used hybridizing box of genetically modified organism chip is divided into loam cake and lower cover two portions at present, and both are separated position, and is bilateral with the fastening of U-shaped aluminum strip.This class hybridizing box also need be in addition with cover plate after putting into chip, and not only troublesome poeration, and its stopping property, reuse are also not ideal enough.
Summary of the invention: the utility model is unreasonable in order to overcome the used hybridizing box structure design of above-mentioned existing genetically modified organism chip, the technological deficiency of stopping property, reuse difference is for people provide a kind of easy to operate, good airproof performance, reuse height, can hatch for the hybridization of gene microarray chip collapsible hybridizing box stable, the homogeneous response condition is provided.
The purpose of this utility model realizes by following technical proposals.
Collapsible hybridizing box of the present utility model is made of loam cake 1 and lower cover 3, is characterized in that loam cake 1 is connected by coupling shaft 4 with lower cover 3, is connected with fixed cover plate 2 through coupling shaft 4 between loam cake 1 and the lower cover 3.
In the such scheme, the inside edge of described loam cake 1 and lower cover 3 is provided with joint strip 5.
In the such scheme, on the described fixed cover plate chip groove 6 is set.
In the such scheme, offer well 7 on the described chip groove 6.
The utility model is that the designer passes through the technical scheme that long-term practice is explored the science practicality of acquisition repeatedly, compared with prior art, because the utility model is fastened on fixed cover plate between hybridizing box loam cake and the lower cover inboard through coupling shaft, fixed cover plate can be reused, can reduce the waste and the operational trouble that cause with cover plate separately.And design of the present utility model makes hybridizing box form the enclosed system isolated with external environment, thereby can prevent the volatilization of chip hybridization liquid.It can be hatched for the hybridization of gene microarray chip reaction conditions stable, homogeneous is provided, and reduces the variation coefficient as a result greatly, and significantly improves the signal to noise ratio of chip hybridization.
Further describe the utility model below by embodiment, the utility model is not limited only to described embodiment.
Description of drawings:
Fig. 1 is the structural representation of the collapsible hybridizing box of the utility model.
Among the figure: 1. loam cake; 2. fixed cover plate; 3. lower cover; 4. coupling shaft; 5. joint strip; 6. chip groove; 7. well.
Embodiment:
As shown in Figure 1: collapsible hybridizing box of the present utility model is made of loam cake 1 and lower cover 3, this routine rectangular loam cake 1 is connected by coupling shaft 4 with a side of lower cover 3, also is connected with the fixed cover plate 2 identical with lower cover 3 shapes with loam cake 1 through coupling shaft 4 between loam cake 1 and the lower cover 3.Fixed cover plate 2 is less than loam cake 1 and lower cover 3, thereby fixed cover plate 2 is positioned among the two when loam cake 1 and lower cover 3 close.The inside edge of this routine described loam cake 1 and lower cover 3 is provided with joint strip 5, the purpose that the internal space of box body is hedged off from the outer world when closing to reach loam cake 1 and lower cover 3.The shape and the size of this routine described loam cake 1 and lower cover 3 and fixed cover plate 2 can also design arbitrarily as required, are not limited only to this example.
As shown in Figure 1: the described fixed cover plate of this example is provided with 6 chip grooves 6, all offers a well 7 on each chip groove 6.The shape of described chip groove 6 and position all can be designed accordingly according to the chip situation of being placed on the lower cover 3.
Can further understand the utility model by the use operating process of product below: during operation, the chip of need reaction is positioned on the lower cover 3, the position is corresponding with the chip groove 6 of fixed cover plate 2, subsequently fixed cover plate 2 is buckled on the chip, join on the chip by well 7 with the mixture of pipettor hybridization solution and pcr amplification product, the loam cake 1 that closes afterwards, heating carry out reaction.
Claims (4)
1. collapsible hybridizing box, it is made of loam cake (1) and lower cover (3), it is characterized in that loam cake (1) is connected by coupling shaft (4) with lower cover (3), is connected with fixed cover plate (2) through coupling shaft (4) between loam cake (1) and the lower cover (3).
2. collapsible hybridizing box according to claim 1 is characterized in that the inside edge of described loam cake (1) and lower cover (3) is provided with joint strip (5).
3. collapsible hybridizing box according to claim 1 is characterized in that being provided with on the described fixed cover plate chip groove (6).
4. collapsible hybridizing box according to claim 3 is characterized in that offering on the described chip groove (6) well (7).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010201609194U CN201785381U (en) | 2010-04-15 | 2010-04-15 | Foldable hybridization box |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010201609194U CN201785381U (en) | 2010-04-15 | 2010-04-15 | Foldable hybridization box |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201785381U true CN201785381U (en) | 2011-04-06 |
Family
ID=43817355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010201609194U Expired - Fee Related CN201785381U (en) | 2010-04-15 | 2010-04-15 | Foldable hybridization box |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201785381U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103808771A (en) * | 2012-11-15 | 2014-05-21 | 赵朝辉 | Biochemical reaction basin for electrochemical biochip |
| CN105749995A (en) * | 2016-04-28 | 2016-07-13 | 宁波大学 | Biological chip hybrid device |
-
2010
- 2010-04-15 CN CN2010201609194U patent/CN201785381U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103808771A (en) * | 2012-11-15 | 2014-05-21 | 赵朝辉 | Biochemical reaction basin for electrochemical biochip |
| CN105749995A (en) * | 2016-04-28 | 2016-07-13 | 宁波大学 | Biological chip hybrid device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110406 Termination date: 20150415 |
|
| EXPY | Termination of patent right or utility model |