CN201755318U - Plug neck multilayer coating film rubber plug - Google Patents
Plug neck multilayer coating film rubber plug Download PDFInfo
- Publication number
- CN201755318U CN201755318U CN2009202847479U CN200920284747U CN201755318U CN 201755318 U CN201755318 U CN 201755318U CN 2009202847479 U CN2009202847479 U CN 2009202847479U CN 200920284747 U CN200920284747 U CN 200920284747U CN 201755318 U CN201755318 U CN 201755318U
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- plug
- neck
- bottle
- plug neck
- rubber
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Abstract
The utility model discloses a plug neck multilayer coating film rubber plug, comprising a bottle plug, the bottle plug comprises a bottle plug body and a plug neck, film layers are coated on the circumferential wall and the bottom surface of the plug neck, no film layer is coated on the sealing surface, the coating films comprises two layers or above two layers of films mutually compounded and provided with different materials. The plug neck multilayer coating film rubber plug performs film coating of the plug neck at the contacting surface of the bottle plug and the medicament, completely solving compatibility problem possibility generated in the direct contact of the medicinal rubber bottle plug and the medicaments, the rubber plug is suitable for a medicine bottle filled with various different medicines, also, the sealing surface is not under film coating, guaranteeing due sealing effect of medicinal rubber bottle plug, and providing a relatively higher medicinal safety.
Description
Technical field
This utility model relates to bottle closure of rubber, mainly relates to a kind of medicinal rubber bottle stopper of filling in the neck overlay film.
Background technology
Medicinal rubber bottle stopper is as a kind of encapsulant of direct contact medicine, must have the excellent close property of institute, good chemical stability and biologically inert, guarantees on the one hand to be hedged off from the outer world in order to avoid medicine generation oxidation or deliquescence etc. lost efficacy goes bad; On the other hand, medicinal rubber bottle stopper itself can not react to each other with medicine and influence the medicine quality.
The existing medicine of producing has the material of bottle closure of rubber use to mainly contain natural rubber (NR), polyisoprene rubber (IR), butyl rubber (IIR) and halogenated butyl rubber (HIIR).Under normal conditions, add multiple compounding ingredient and adopt the mould pressing process manufacturing.All there is the chemism that has nothing in common with each other in various compounding ingredients in the cooperation system of support formation plug characteristic, plug with direct contact of medicine in, have chemically active material and medicine generation chemical reaction in the prescription, the result of these chemical reactions has directly influenced stability of drug.So strictly speaking, the extractable matter of plug is not that the problem that does not have is arranged to the influence of medicine stability, but with having how much to measure medicine is brought pollution how long.Simultaneously, because the activity difference of medicine itself is very big, emerging in an endless stream of new drug in addition, so up to the present, medicinal rubber bottle stopper is limit by material material and prescription level, does not also have a kind of prescription of uniqueness can satisfy all pharmaceutical preparation.Here it is elastomer pharmaceutical pack material with direct contact of medicine in the compatibility and suitability problem.Chinese patent 200620105810.4 provides a kind of medicinal rubber bottle stopper of filling in the neck overlay film, solves contingent consistency problem in direct contact of medicinal rubber bottle stopper and medicine, and the while sealing surface is overlay film not, has guaranteed the due sealing function of medicinal rubber bottle stopper.But,, characteristics are respectively arranged, so single film is difficult to satisfy the requirement of all medicines because medicine is numerous.
Summary of the invention
It is that a kind of plug neck of design has multilamellar overlay film plug that the technology that this utility model need solve is cutd open problem, to overcome the defective that prior art exists, is applicable to the medicine bottle of the multiple different medicines of filling.
This utility model solves the technical scheme that its technical problem adopts: plug neck multilamellar overlay film plug, comprise bottle stopper, described bottle stopper is made up of bottle stopper main body and plug neck, be covered with rete on the circumferential wall of described plug neck and on the bottom surface of plug neck, do not carried out rete on the described sealing surface, said rete comprises the thin film of two-layer or two-layer above mutual compound different materials.
Be covered with rete on the circumferential wall of described plug neck 2/3rds and on the bottom surface of plug neck.
The bottom surface of described plug neck can be a plane, also can be an arc surface or other shapes.
Cylindrical or other shapes of described plug neck.
Described sealing surface is meant the part of removing the plug neck on the surface of bottle stopper main body.
The two-layer composite membrane that this utility model can adopt polyester/poly-office alkene, polyester/polypropylene, PVD/PVC, nylon/polyethylene, nylon/polypropylene, polyester/nylon to constitute, or the two-layer above composite membrane that adopts polyester/aluminum foil/polyethylene or polypropylene or its modifier, polyester/polyurethane/polyethylene or polypropylene, polyester/aluminium foil/polyurethane/polypropylene, polyester/polypropylene/polyurethane/polyethylene to constitute, and can adopt that disclosed method is prepared in the Chinese patent application number 03129039.6, specifically comprise the steps:
The position that need answer film at molded plug is coated with binding agent:
The plug that heating scribbles binding agent to remove the solvent in the binding agent, can preferentially adopt hot air, heating-up temperature to be generally 50～85 ℃.
The composite membrane that macromolecular material is made is heated to plastic, place on the above-mentioned gummed plug, under vacuum condition with stock mould with compound sticking being pressed on the plug of composite membrane;
Excise unnecessary composite membrane, promptly obtain plug neck multilamellar overlay film plug of the present utility model.
The effect that this utility model is useful is: only with bottle stopper with medicine contact surface plug neck overlay film, solve contingent consistency problem in direct contact of medicinal rubber bottle stopper and medicine fully, be applicable to the medicine bottle of the multiple different medicines of filling, the while sealing surface is overlay film not, has guaranteed the due sealing function of medicinal rubber bottle stopper.
Description of drawings
Fig. 1 is the subjective structural representation of this utility model embodiment 1
Fig. 2 is the main TV structure sketch map of this utility model embodiment 2
Fig. 3 is that this utility model embodiment 1 described bottle stopper is installed in the main TV structure sketch map on the bottle
Fig. 4 is the main TV structure sketch map of this utility model embodiment 3
Reference numeral: 1, bottle stopper, 2, the plug neck, 3, the bottle stopper main body, 4, rete, 5, sealing surface, 6, bottle.
The specific embodiment
Following structure drawings and Examples are described in further detail this utility model.
Embodiment 1: as shown in Figure 1, a kind of plug neck multilamellar overlay film plug comprises bottle stopper 1, and described bottle stopper 1 mainly is made up of bottle stopper main body 3 and plug neck 2, is being covered with rete 4 on the circumferential wall of plug neck 2 and on the bottom surface of plug neck 2, and overlay film is no more than A, D, but near A, D point; On sealing surface 5, be not covered with rete 4.Plug neck 2 is cylindrical, and its bottom surface is a plane, and described sealing surface 5 is meant the part of removing plug neck 2 on the surface of bottle stopper main body 3.
After being installed on the bottle 6, bottle stopper 1 as shown in Figure 3, guarantees bottle stopper plug neck 2 overlay films and sealing surface 5 overlay film not.Promptly along ABCD face overlay film, and overlay film is no more than A, D, and said rete 4 comprises the thin film of two-layer mutual compound different materials.
Embodiment 2: as shown in Figure 2, difference from Example 1 is: the bottom surface at plug neck 2 is an arc face, and said rete 4 comprises the thin film of three layers of mutual compound different materials.
Embodiment 3: as shown in Figure 4, difference from Example 1 is: be covered with rete on the circumferential wall of plug neck 2/3rds and on the bottom surface of plug neck, overlay film surpasses B, C point on the position of plug neck 2/3rds, preferentially will be more than 1/2nd, best more than 2/3rds, said rete 4 comprises the thin film of four layers of mutual compound different materials.
This utility model plug neck multilamellar overlay film plug is plug with the natural gum, the composite membrane that adopts single-layer polypropylene, polyester/polypropylene, polyester/aluminum foil/polypropylene to constitute respectively, film thickness is 8, polyester thickness is 1.5, add and be placed on the 100ml saline bottle, add injection water 100ml, the sterilization of lid back, the microgranule in the mensuration water for injection and the maximal ultraviolet absorption of full wavelength scanner, the result is as follows:
| ＞2μ | ＞10μ | ＞25μ | Ultraviolet absorption value | |
| Single-layer polypropylene | 100 | 6 | 0 | 0.154 |
| Polyester/polypropylene | 25 | 1.2 | 0 | 0.070 |
| Polyester/aluminum foil/polypropylene | 20 | 1.0 | 0 | 0.045 |
This shows that adopt the multilamellar overlay film, microgranule and uv absorption thing reduce significantly.
Claims (4)
1. fill in neck multilamellar overlay film plug, comprise bottle stopper (1), described bottle stopper (1) is made up of bottle stopper main body (3) and plug neck (2), be covered with rete (4) on the circumferential wall of described plug neck (2) and on the bottom surface of plug neck (2), do not carried out rete (4) on the described sealing surface (5), it is characterized in that: said rete (4) comprises the thin film of two-layer or two-layer above mutual compound different materials.
2. plug neck multilamellar overlay film plug according to claim 1 is characterized in that: be covered with rete (4) on the circumferential wall of described plug neck (2) 2/3rds and on the bottom surface of plug neck (2).
3. plug neck multilamellar overlay film plug according to claim 1, it is characterized in that: the bottom surface of described plug neck (2) can be a plane, also can be an arc surface.
4. plug neck multilamellar overlay film plug according to claim 1, it is characterized in that: described plug neck (2) is cylindrical.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009202847479U CN201755318U (en) | 2009-12-07 | 2009-12-07 | Plug neck multilayer coating film rubber plug |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009202847479U CN201755318U (en) | 2009-12-07 | 2009-12-07 | Plug neck multilayer coating film rubber plug |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201755318U true CN201755318U (en) | 2011-03-09 |
Family
ID=43642584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009202847479U Expired - Fee Related CN201755318U (en) | 2009-12-07 | 2009-12-07 | Plug neck multilayer coating film rubber plug |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201755318U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102670400A (en) * | 2012-04-26 | 2012-09-19 | 深圳致君制药有限公司 | Pharmaceutical packaging composition for injection and preparation method thereof |
| CN103271822A (en) * | 2013-05-22 | 2013-09-04 | 盛州橡塑胶（苏州）有限公司 | Seamless laminated rubber plug and preparation method thereof |
| CN105232326A (en) * | 2015-10-10 | 2016-01-13 | 江苏中金玛泰医药包装有限公司 | Outer composite film cover for insertion openings of plastic containers for intravenous injection and manufacturing method |
| WO2016180064A1 (en) * | 2015-05-12 | 2016-11-17 | 江苏华兰药用新材料股份有限公司 | Modified membrane-coated rubber plug |
-
2009
- 2009-12-07 CN CN2009202847479U patent/CN201755318U/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102670400A (en) * | 2012-04-26 | 2012-09-19 | 深圳致君制药有限公司 | Pharmaceutical packaging composition for injection and preparation method thereof |
| CN103271822A (en) * | 2013-05-22 | 2013-09-04 | 盛州橡塑胶（苏州）有限公司 | Seamless laminated rubber plug and preparation method thereof |
| WO2016180064A1 (en) * | 2015-05-12 | 2016-11-17 | 江苏华兰药用新材料股份有限公司 | Modified membrane-coated rubber plug |
| CN105232326A (en) * | 2015-10-10 | 2016-01-13 | 江苏中金玛泰医药包装有限公司 | Outer composite film cover for insertion openings of plastic containers for intravenous injection and manufacturing method |
| CN105232326B (en) * | 2015-10-10 | 2018-04-24 | 江苏中金玛泰医药包装有限公司 | A kind of composite membrane outer cover and manufacture method for being used to be injected intravenously plastic containers insert port |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110309 Termination date: 20141207 |
|
| EXPY | Termination of patent right or utility model |