CN201670897U - Electrospinning device for producing artificial blood vessels - Google Patents
Electrospinning device for producing artificial blood vessels Download PDFInfo
- Publication number
- CN201670897U CN201670897U CN2010201231532U CN201020123153U CN201670897U CN 201670897 U CN201670897 U CN 201670897U CN 2010201231532 U CN2010201231532 U CN 2010201231532U CN 201020123153 U CN201020123153 U CN 201020123153U CN 201670897 U CN201670897 U CN 201670897U
- Authority
- CN
- China
- Prior art keywords
- artificial blood
- blood vessel
- gathering
- turntable
- blood vessels
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Landscapes
- Spinning Methods And Devices For Manufacturing Artificial Fibers (AREA)
- Nonwoven Fabrics (AREA)
Abstract
The utility model discloses an electrospinning device for producing artificial blood vessels, which comprises a solution storage unit, a jet unit, a collecting unit and a high-voltage static electricity generator for providing a strong electric field between the jet unit and the collecting unit, wherein the collecting unit comprises a translation table, a rotating table and a receiving rod, and the receiving rod is fixed on the rotating table, which is fixed on the translation table. The utility model can facilitate the industrialized and mass production of artificial blood vessels by the electrospinning technology.
Description
Technical field
The utility model relates to electric spinning device, relates in particular to a kind of artificial blood vessel's of preparation electric spinning device.
Background technology
Blood vessel is the pipeline of transportation blood, sends to nutrition and oxygen for the histoorgan of whole body, takes away metabolic waste.Often jeopardize human life safety with the blood vessel diseases associated, as the blood vessel dilatation that aortic aneurysm causes, arteriarctia that atherosclerotic causes even obturation, the heart disease that the coronary artery sclerosis causes etc.Therefore when the blood vessel of human body part can not guarantee the normal blood supply of histoorgan owing to reasons such as artery sclerosis, aging or breakages, need the employing artificial blood vessel to replace, put up a bridge or surgical operation therapy such as intervention.
The existing so far nearly 60 years history of the exploitation of artificial blood vessel and development, in clinical practice at present, artificial blood vessel has been obtained satisfied effect aspect the main artery substituting, but (research of internal diameter≤6mm) also has big distance because key problems such as biocompatibility and compliance, patency rate are still unresolved from practical application to small-bore artificial blood vessel.
Electrospinning claims " electrospinning silk " again, is that a kind of polymer solution or melt of utilizing forms the technology that injection stream is carried out spinning process under the highfield effect.In recent years, electrospinning causes people's extensive concern as a kind of effective way that can produce nanofiber continuously, and the polymer that successfully carries out electrospinning processing at present in the world is above 30 kinds.The fiber diameter range that electrospinning makes is generally at 3nm～5um, than the little several magnitude of the fibre diameter that makes with conventional method.By the artificial blood vessel that electricity spinning fibre makes, has the porosity height, advantage such as specific area is big, fiber fine degree and homogeneity height, draw ratio are big.These with conventional method the good characteristic that can't obtain, given the electricity spinning fibre application prospects.In addition, electrospinning silk technology also has fast, efficient, advantages such as equipment is simple, easy operating, can be used for preparation complicated, exempt to sew up support, be control high-molecular biologic goods pattern, porosity and the effective way of regulating component.
Existing electric spinning device mainly is made up of following 4 parts:
HV generator: the highfield between injection apparatus and gathering-device is provided, and generally adopting maximum output voltage is the high direct voltage electrostatic generator of 30～100KV.
Solution storage device: can use syringe or liquid storage pipe etc., wherein fill polymer solution.
Injection apparatus: injection apparatus is capillary or the syringe needle of internal diameter 0.5～2mm.Can regulate hydrostatic pressure by air pump is installed in the solution storage device, or make polymer solution form drop at spinning nozzle with the method for the slow pushing syringe of numerical controlled machinery device.
Gathering-device: can select metal plate, grid or cylinder, rod iron according to the requirement of experimental result.Utilize difform gathering-device, can make the nonwoven fabric product of various character.Gathering-device ground connection is like this because the potential difference between nozzle and gathering-device forms high electric field between the two.Electric-field intensity can be by the output valve of HV generator and the distance control between injection apparatus and gathering-device.
But still there is not directly to prepare at present artificial blood vessel's electric spinning device.
Summary of the invention
At the deficiencies in the prior art, the purpose of this utility model provides a kind of electric spinning device that is used to prepare the artificial blood vessel, is convenient to industrialization, scale that electrospinning silk technology prepares the artificial blood vessel.
To achieve these goals, the technical solution of the utility model is: a kind of electric spinning device that is used to prepare the artificial blood vessel, it comprises solution storage device, injection apparatus, gathering-device and the HV generator that is used to provide the highfield between injection apparatus and gathering-device, described gathering-device comprises translation stage, turntable, reception rod, receive rod and be fixed on the turntable, turntable is fixed on the translation stage.
Described turntable is a high-speed rotary motor, and described reception rod is fixedly connected by fixture and high speed shaft coupling in the rotating shaft with high-speed rotary motor.
The beneficial effects of the utility model are: 1. fill the domestic gaps; 2. drive the reception rod and carry out high speed rotary motion, can regulate rotating speed according to the needs of different polymer solutions and make the electrospinning silk on receiving system, be orientated deposition; 3. drive the reception rod and carry out horizontal reciprocating movement, guarantee that electrospinning silk uniform deposition is in gathering-device; 4. can select the artificial blood vessel of the various internal diameters of reception rod preparation of different-diameter according to actual needs; 5. the electrospinning receiving efficiency be can improve, industrialization and popularization that the electrospinning silk prepares artificial blood vessel's technology helped; 6. can the uniform nanofiber nonwoven of one-shot forming manufacturing artificial blood vessel.
Description of drawings
The utility model is described in further detail below in conjunction with accompanying drawing.
Fig. 1 is a composition schematic diagram of the present utility model.
Fig. 2 is the positive overall structure schematic diagram of gathering-device of the present utility model.
Fig. 3 is a gathering-device of the present utility model side overall structure schematic diagram.
The specific embodiment
See also Fig. 1, the electric spinning device that being used to of present embodiment prepares the artificial blood vessel comprises solution storage device 5, injection apparatus 6, gathering-device 7 and is used to provide injection apparatus 6 and the HV generator 8 of the highfield of 7 of gathering-devices.See also Fig. 2 and Fig. 3, gathering-device 7 comprises reception rod 1, high speed shaft coupling 2, turntable 3, translation stage 4, receiving rod 1 is fixedly connected on turntable 3 by fixture and high speed shaft coupling 2, this turntable 3 is a high-speed rotary motor, drive reception rod 1 by it and carry out high speed rotary motion, this turntable 3 is fixed on the translation stage 4 simultaneously, can carry out horizontal reciprocating movement in the rotation at a high speed thereby receive rod 1.Translation stage can carry out horizontal reciprocating movement, reciprocal distance＜100mm, the speed of service is 0.1～5mm/S, can regulate its reciprocal distance and the speed of service, turntable can carry out the high speed rotation, rotating speed is 100～3000r/min, can regulate rotating speed according to the requirement of different polymer solutions and make the electrospinning silk be orientated deposition on receiving system, receives bar fixing device and is used for fixing the reception rod.Can select the reception rod of different-diameter according to preparation different inner diameters artificial blood vessel's needs, be connected on the high speed shaft coupling by fixation workpiece.
During use, at first in device for storing liquid, fill with the electrospinning solution for preparing, under the self gravitation effect or regulate flow velocity by electronic syringe pump and make drop be full of injection apparatus but do not drip.Select the reception rod of different-diameter to be fixed on the turntable on demand, adjust the reciprocating distance and the speed of the rotating speed and the adjustment translation stage of turntable behind the connection power supply.Start HV generator, after the energising, because injection apparatus (spinning head) has positive electricity, and gathering-device ground connection is no-voltage, and under the electric field force effect, spinning solution is drawn out from spinning head, form high velocity jet, and be received the rod collection rapidly, the solvent in the spinning solution volatilizees rapidly simultaneously.Behind the deenergization, unload and receive rod, take off electrospinning silk product (artificial blood vessel).
The utility model is rational in infrastructure, easy to operate, and electrospinning silk collection efficiency height can form the artificial blood vessel that is evenly distributed, and helps industrialization and development that electrospinning silk technology prepares the artificial blood vessel technology, thereby is worthy of popularization.
Claims (2)
1. electric spinning device that is used to prepare the artificial blood vessel, it comprises solution storage device, injection apparatus, gathering-device and the HV generator that is used to provide the highfield between injection apparatus and gathering-device, it is characterized in that, described gathering-device comprises translation stage, turntable, reception rod, receive rod and be fixed on the turntable, turntable is fixed on the translation stage.
2. the electric spinning device that is used to prepare the artificial blood vessel according to claim 1 is characterized in that, described turntable is a high-speed rotary motor, and described reception rod is fixedly connected by fixture and high speed shaft coupling in the rotating shaft with high-speed rotary motor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010201231532U CN201670897U (en) | 2010-02-25 | 2010-02-25 | Electrospinning device for producing artificial blood vessels |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010201231532U CN201670897U (en) | 2010-02-25 | 2010-02-25 | Electrospinning device for producing artificial blood vessels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201670897U true CN201670897U (en) | 2010-12-15 |
Family
ID=43328309
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010201231532U Expired - Fee Related CN201670897U (en) | 2010-02-25 | 2010-02-25 | Electrospinning device for producing artificial blood vessels |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201670897U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101785714A (en) * | 2010-02-25 | 2010-07-28 | 王深明 | Electric spinning device for preparing artificial blood vessel |
-
2010
- 2010-02-25 CN CN2010201231532U patent/CN201670897U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101785714A (en) * | 2010-02-25 | 2010-07-28 | 王深明 | Electric spinning device for preparing artificial blood vessel |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101785714A (en) | Electric spinning device for preparing artificial blood vessel | |
| CN201343585Y (en) | Electrostatic spinning device for producing nanofiber | |
| CN105839204B (en) | Layering intravascular stent formation system and method based on electrostatic direct write and electrostatic spinning technique | |
| CN102776583B (en) | Portable handheld electrostatic spinning device | |
| CN106222763B (en) | A kind of continuous electrostatic spinning apparatus and its method for preparing spiral micro nanometer fiber | |
| CN104451910B (en) | The electric spinning equipment that jet fixed point induces | |
| CN101831762A (en) | Composite fiber porous membrane composited by ornithoctonus huwena threads and polylactic acid and method for producing same | |
| CN106868675A (en) | A kind of continuous preparation device of nanofiber covering yarn | |
| CN203904512U (en) | Novel multifunctional nano-fiber electrostatic spinning machine | |
| CN103757718B (en) | A kind of flat plate free liquid level coaxial electrostatic spinning method and device thereof | |
| CN209906933U (en) | Ultraviolet light-assisted electrostatic spinning device | |
| CN103305933B (en) | A kind of rotating porous electrostatic spinning apparatus | |
| CN104862799A (en) | Method for preparing graphene/polymer orderly micro-nanometer composite fiber through magnetic spinning | |
| CN201670897U (en) | Electrospinning device for producing artificial blood vessels | |
| CN207933564U (en) | A kind of needleless electrostatic spinning machine | |
| CN203451655U (en) | Rotary porous electrostatic spinning device | |
| CN110747523B (en) | Two-stage differential melt electrostatic spinning device | |
| CN105671657B (en) | A kind of small-caliber artificial blood vessel preparation facilities based on electrostatic spinning | |
| CN104695031A (en) | Electrostatic spinning device | |
| CN102191574B (en) | Nano fiber batch manufacturing device | |
| CN103484954B (en) | A kind of electrostatic spinning apparatus of preparing nanofiber | |
| CN208472238U (en) | A kind of electric field-assisted original position fixed point electrostatic spinning apparatus | |
| CN105755554B (en) | A kind of small-caliber artificial blood vessel preparation method based on electrostatic spinning | |
| CN206428353U (en) | One kind vibration Multi-tip electrostatic spinning apparatus | |
| CN210974940U (en) | Needleless roller type electrostatic spinning equipment |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20101215 Termination date: 20190225 |