CN201622252U

CN201622252U - Micro-focus X-ray phase contrast imaging experimental platform

Info

Publication number: CN201622252U
Application number: CN201020139911XU
Authority: CN
Inventors: 武杰; 吴健; 金倞; 陈家璧; 张学龙
Original assignee: University of Shanghai for Science and Technology
Current assignee: University of Shanghai for Science and Technology
Priority date: 2010-03-25
Filing date: 2010-03-25
Publication date: 2010-11-03
Anticipated expiration: 2020-03-25

Abstract

The utility model relates to a micro-focus X-ray phase contrast imaging experimental platform, capable of respectively controlling a sample platform, a detector platform and a sample turntable arranged on corresponding screw rods to move along the screw rods by controlling a first, second and third screw rods. The bottom of the experimental platform is provided with a fixed sliding rail on two sides for loading and sliding corresponding platform along the screw rod. The experimental platform is capable of preventing condition restriction of synchronous radiation sources so as to perform phase contrast imaging experiment in the common laboratory room; the experimental platform is integrated with relevant experimental devices, and provides a convenient and flexible operation mode and an imaging parameter adjusting mode, so as to meet adjustment requirement of different kinds and sizes of samples and different experiment effects; the rotation and movement functions of the sample turntable are implemented separately, such that it is possible to provide conditions for farther phase CT scanning experiments.

Description

The experiment porch of microfocus X-ray phase contrast imaging

Technical field

The utility model relates to a kind of experimental provision, particularly a kind of experiment porch of microfocus X-ray phase contrast imaging.

Background technology

In in the past more than 100 year,, in fields such as medical science, material science, industrial nondestructive testing, obtained to use extremely widely based on the traditional X-ray radial imaging technology that absorbs contrast mechanism.Yet for for the sample of light element because light element almost do not absorb X ray or has only seldom absorption, perhaps when the absorption difference between the different light elements very little, thereby it is not good to cause routine at these materials to absorb imaging effect.And diverse image-forming mechanism is adopted in the imaging of X ray phase contrast, it is by test sample the degree that the X phase of line changes to be carried out imaging, changed traditional detection fully to X line absorption intensity, it is a kind of weak new method that absorbs specimen material of studying, its spatial resolution can reach micron order, is a new technology of biologic soft tissue, light element sample that density is more or less the same being carried out imaging.In recent years, the applied research of this method on clinical medicine also more and more causes people's attention, comprises the high-resolution imaging research to aspects such as breast tissue, tumor tissues, vascular system, respiratory systems.

The imaging of X ray phase contrast has three kinds of diverse ways usually according to the difference of image-forming mechanism: the coaxial holographic imaging of X ray interference imaging, diffraction enhanced imaging and class.The phase contrast imaging mainly depends on the refraction action of X ray, and is irrelevant with the absorption of X ray, thereby reduces the absorbed dose of sample to X ray, reaches the effect of minimizing to the radiation damage of biological tissue.Wherein the coaxial X ray phase contrast imaging of class is had relatively high expectations to the spatial coherence of light source, and former overwhelming majority research is based on all that synchrotron radiation light source carries out, but this considerable restraint that can be subjected to experimental provision based on the application of synchrotron radiation light source in practice.

Since polychromatic x-ray source that people such as S.W.Wilkins successfully adopt the microfocus X-ray tube to be produced first carries out phase contrast imaging research, by little focus X-ray ray tube, adopt this little focus X-ray line phase contrast imaging principle to carry out various applied researcies, just more and more obtain everybody approval.Because it requires comparatively simple to imaging device, mainly form by microfocus X-ray source, sample mounting table, image received device, but in experiment, often need regulate repeatedly the distance between above-mentioned three devices, therefore, this just needs a suitable experiment porch to carry above-mentioned three experimental provisions, also can regulate each relevant experiment parameter simultaneously easily.

Summary of the invention

The utility model is can not satisfy the problem that needs are regulated in experiment at carrying platform in the imaging device, a kind of experiment porch of microfocus X-ray phase contrast imaging has been proposed, reasonably to place relevant experimental provision, regulate relevant experiment parameter easily, thereby make compacter, the easier operation of whole experiment device, so that finish various little focus X-ray line phase contrast imaging experiments better.

The technical solution of the utility model is: a kind of experiment porch of microfocus X-ray phase contrast imaging, the secured in parallel first control screw rod and the second control screw rod above the experiment porch, example platform is vertically fixed on control screw rod top, detector platform is vertically fixed on control screw rod top, fix the 3rd control screw rod above the example platform, the 3rd control screw rod is vertical controls screw rod with the first control screw rod and second, sample rotary table is fixed on the 3rd control screw rod top, by controlling first, two, three screw rods can be controlled example platform respectively, detector platform and sample rotary table move along the screw rod direction, and fixed rack is equipped with on both sides, experiment porch bottom.

An inner motor, the control sample rotary table anglec of rotation of placing of described sample rotary table.

The beneficial effects of the utility model are: the experiment porch of the utility model microfocus X-ray phase contrast imaging, this experiment porch have been avoided adopting the constraint of synchrotron radiation source, thereby can carry out the experiment aspect the phase contrast imaging in common lab; This experiment porch reasonable integration related experiment be installed on one, the convenient, flexible mode of operation and the regulative mode of imaging parameters are provided, can adapt to the sample of variety classes, different size, the adjusting requirement of different experiments effect; The separating controlling of sample rotary table rotating function and locomotive function realizes, can provide condition for further phase place CT scan experiment.

Description of drawings

Fig. 1 is the experiment porch fundamental diagram of the utility model microfocus X-ray phase contrast imaging;

Fig. 2 is the experiment porch synoptic diagram of the utility model microfocus X-ray phase contrast imaging;

Fig. 3 is the experiment porch schematic top plan view of the utility model microfocus X-ray phase contrast imaging;

Fig. 4 is the experiment porch screw rod and the pulley structure synoptic diagram of the utility model microfocus X-ray phase contrast imaging;

Fig. 5 is the experiment porch sample rotary table inner structure synoptic diagram of the utility model microfocus X-ray phase contrast imaging.

Embodiment

Setting up the common X ray phase contrast imaging experimental system of a cover, adopt the X ray phase contrast imaging mode in little focus source, is a feasible experimental program, and according to fresnel diffraction theory, its principle of work can be expressed as shown in Figure 1.Corresponding with it experiment porch synoptic diagram is illustrated in fig. 2 shown below, and as can be seen from the figure, the experiment porch basic configuration of this formation method comprises: microfocus X-ray source C, example platform B, image detector A.Wherein two of imaging major parameters are respectively: source object distance R1, object image distance R2, its imaging physical basis can be derived by fresnel diffraction and be obtained, and the detected image planes light distribution of detector can be expressed as:

Wherein M=(R1+R2)/R1 is an enlargement factor, I ₀Be the light intensity value on the object plane, this shows,, that is to say the second-order differential that is proportional to the sample interior electron density be proportional to the second-order differential of sample as the light distribution on the plane to the phase shift of X line, therefore, little focus X-ray line phase contrast imaging is more responsive to the structure boundary video picture of sample interior variable density.Therefore, the X ray phase contrast imaging can carry out blur-free imaging to the marginal portion of sample interior different structure.

According to above-mentioned image-forming principle, the utility model has designed an incorporate experiment porch, reasonably to place above-mentioned relevant experimental provision, and feasible adjusting and operation to imaging parameters, become more convenient and accurate, thereby can finish the central needed operations of experiment, this experiment porch side view as shown in Figure 2.Because microfocus X-ray source itself is fixed on outside the experiment porch, so as can be seen from Figure 2, this experiment porch mainly comprises 5 parts: shown in Fig. 3,4,5, place the example platform 1 of sample rotary table; Place the detector platform 2 of detector;

Control screw rod

4,5,6; Fixed rack 7 is placed on both sides, experiment porch 3 bottom, be used for carrying and and the screw rod corresponding platform that slides together, to realize combining closely and can controlling respectively of example platform and detector platform; Sample rotary table 8 is used for placement, replacing and rotary sample, can place a motor in this sample rotary table inside, can be used for making sample to rotate a certain angle.Secured in parallel

control screw rod

4,5 above the experiment porch 3, example platform 1 is vertically fixed on control screw rod 4 tops, detector platform 2 is vertically fixed on control screw rod 5 tops, fixing control screw rod 6 above the example platform 1, control screw rod 6 vertical and

control screw rods

4,5, sample rotary table 8 is fixed on control screw rod 6 tops, can control example platform 1, detector platform 2 and sample rotary table 8 respectively by

control screw rod

4,5,6 and move along the screw rod direction.

In formation method, relation between source object distance R1 and the object image distance R2 is even more important to imaging, therefore this design for Experimental Platform mainly is to realize the function of the following aspects: 1, the platform of placing and changing detector is provided, the platform of placement, replacing and control sample is provided; 2,, comprise 150 centimetres moving range of X-direction, 60 centimetres moving range of Y direction to the mobile control of example platform; 3,, mainly be 150 centimetres moving range in X-direction to the mobile control of detector platform; 4, to the rotation of sample rotary table and highly adjusting control, comprise the rotations around vertical axis of 360 degree, 10 centimetres lifting control up and down.Function 2 and function 4 combine and just can realize that three are moved and Spin Control to laboratory sample, and therefore whole experiment porch can be conveniently implemented in the control operation of geometric parameter in the phase contrast imaging.

Experiment porch operation: by driven by motor screw rod 4, under the cooperation of corresponding opposite side fixed block, can drive moving of example platform front and back position, thereby realize the adjusting of parameters R 1; By driven by motor screw rod 5, under the cooperation of corresponding opposite side fixed block 7, can drive moving of detector platform front and back position, thereby realize the adjusting of parameters R 2; By driven by motor screw rod 6, can drive be placed with sample rotary table 8 plant moving of position, the thing platform left and right sides, thereby realize adjustment to the sample center, and make things convenient for the replacing of sample; Sample rotary table 8 is placed on the position of the example platform 1 in the accompanying drawing 3, rotates by the driven by motor sample stage that is placed on sample rotary table inside, thereby sample is rotated a certain angle.

Claims

1. the experiment porch of a microfocus X-ray phase contrast imaging, it is characterized in that, the secured in parallel first control screw rod (4) and the second control screw rod (5) above the experiment porch (3), example platform (1) is vertically fixed on control screw rod (4) top, detector platform (2) is vertically fixed on control screw rod (5) top, fix the 3rd control screw rod (6) above the example platform (1), the 3rd control screw rod (6) is vertical controls screw rod (5) with the first control screw rod (4) and second, sample rotary table (8) is fixed on the 3rd control screw rod (6) top, by controlling first, two, three screw rods (4,5,6) can control example platform (1) respectively, detector platform (2) and sample rotary table (8) move along the screw rod direction, and fixed rack (7) is equipped with on both sides, experiment porch (3) bottom.

2. according to the experiment porch of the described microfocus X-ray phase contrast imaging of claim 1, it is characterized in that an inner motor, control sample rotary table (8) anglec of rotation of placing of described sample rotary table (8).