CN201578394U - Rat weightlessness simulation device used for test - Google Patents

Rat weightlessness simulation device used for test Download PDF

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Publication number
CN201578394U
CN201578394U CN2009203187391U CN200920318739U CN201578394U CN 201578394 U CN201578394 U CN 201578394U CN 2009203187391 U CN2009203187391 U CN 2009203187391U CN 200920318739 U CN200920318739 U CN 200920318739U CN 201578394 U CN201578394 U CN 201578394U
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CN
China
Prior art keywords
rat
mus
holder
renovate
cephalostat
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN2009203187391U
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Chinese (zh)
Inventor
朱超
李云庆
王文
汪伟
每晓鹏
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Fourth Military Medical University FMMU
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Fourth Military Medical University FMMU
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Priority to CN2009203187391U priority Critical patent/CN201578394U/en
Application granted granted Critical
Publication of CN201578394U publication Critical patent/CN201578394U/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

The utility model belongs to the technical field of a test apparatus and particularly relates to a rat weightlessness simulation device used for a test, wherein the device is suitable for fixing a rat and doing the research for weightlessness, medicine and other aspects in the aerospace medicine field. The rat weightlessness simulation device is characterized in that a rat fixator is connected on a rotating support; one end of the support is fixed with an angle gauge; a rotating pointer is arranged on the angle gauge; the pointer is fixedly connected with a rotating shaft of the rotating support; the rat fixator is formed by connecting a fixed seat and a flap; and one side of the flap is rotatably connected with the fixed seat, and the other side thereof is buckled or blocked with the fixed seat. The rat weightlessness simulation device used for the test has simple structure, can accurately control the low-position inclination angle of a rat head and can better solve the problem that the rat is incoordinate in the catching and fixing processes; and the rat can be closed in a fixed barrel, so as to facilitate the test operations such as the intraperitoneal medicine injection, the caudal vein blood drawing and the like and do the medium-term and long-term weightlessness simulation researches.

Description

Experiment rat simulated weightlessness device
Technical field
This utility model belongs to experiment equipment technical field, and the experiment rat simulated weightlessness device of aspect researchs such as weightlessness, medicine is fixed and carried out in particularly a kind of aerospace medicine field that is applicable to rat.
Background technology
Aerospace medicine research often needs suitable animal model, the adaptations of the cardiovascular system of animal, skeletal musculature, nervous system, immune hormonal system under the weightless situation of observation ground simulation.One adopts the mode of afterbody suspention toward the rat model that adopts more, but the afterbody suspention can't keep the stablizing of constant and experiment condition at angle of inclination.And rat tails ischemic necrosis decortication phenomenon such as fester usually appears in afterbody suspention in medium-term and long-term simulated weightlessness research.Existing rat simulated weightlessness apparatus structure complexity.Simultaneously, the operation comprise needs such as abdominal cavity medicine injection, tail vein blood, behavioristics's test fixedly rat to obtain stable operating condition.The mode of original fixedly rat is utilized the boring habit of rat more, allows mouse pierce the tubular holder voluntarily, fixedly carries out experimental implementation behind the rat buttocks.Often occur rat in the real process because of repeatable operation, reasons such as memory formation, fear, drug effect initiatively do not pierce the situation of stationary magazine creel, and the order experiment can't be carried out.
Summary of the invention
The purpose of this utility model is to provide a kind of experiment rat simulated weightlessness device, and its simple and practical property is strong, easy to operate, and rat is not had injury; And rat is fixed by rat is closed in the mode of stationary magazine creel.
The technical solution of the utility model is: design a kind of experiment rat simulated weightlessness device, it is characterized in that: its big rat holder is connected on the support of rotation, support one end is fixed with protractor, the pointer that rotation is arranged on the protractor, the rack shaft of pointer and rotation is fixed together, its big rat holder is connected and composed with renovating by holder, renovates on one side and is rotationally connected another side and holder snapping or clamping with holder.
Described holder has Mus cephalostat, lumbar injection hole, lower limb holddown groove, defecate groove in the past backward successively, and Mus diet hole is arranged on the Mus cephalostat.
Described renovating is connected with pressure Mus plate.
Described renovating is the branch body structure, renovate before being divided into and after renovate, preceding renovate and after renovate separate, preceding renovate and after the hasp of connection is arranged between renovating.
Reed is arranged on the described pressure Mus plate and press the Mus plate to regulate bolt.
Described Mus cephalostat is the cylinder that there is vertebra cylinder cavity at the middle part, the diameter of vertebral body cavity progressively enlarges with the Mus head shapes after by forward direction and adapts, there is Mus diet hole at cylinder front end center and is communicated with the vertebral body cavity, for the rats eating drinking-water of closing in big rat holder; The hold-down nut of Mus cephalostat by the cylindrical shell side-lower fixedlyed connected with the fixedly chute of holder, unscrew hold-down nut after, move forward and backward the Mus cephalostat, to adapt to the rat that consubstantiality is not grown, hold-down nut fixedly can move forward and backward in the chute.
On the supporting plate of the support of described rotation slot is arranged, slot is plugged on the vertebral body base of big rat holder.
A plurality of slots are arranged, a plurality of big rat holders of pegging graft simultaneously on the supporting plate of described swinging mounting.
The beneficial effects of the utility model are, this can be easily fixedly the experiment of rat with rat simulated weightlessness device, by rat is closed in the mode of stationary magazine creel rat is fixed, by angle measurement unit, can control the experimental rat angle of inclination easily simultaneously.It has solved the uppity problem of head down tilt angle in the weightless process of rat ground simulation preferably; When being convenient to research low level differing tilt angles simulated weightlessness, the adaptations of systems such as rat cardiovascular system, musculoskeletal system, nervous system, immune hormonal system; Solved its ill-matched problem when arresting rat simultaneously, rat can have been closed in stationary magazine creel, carried out intraperitoneal injection, tail vein easily and get experimental implementation in the simulated weightlessness process such as blood.
Description of drawings
Below in conjunction with drawings and Examples this utility model is described further.
Fig. 1 embodiment overall structure sketch map;
Big rat holder lateral plan among Fig. 2 embodiment;
Big rat holder crown view among Fig. 3 embodiment;
The big rat holder vertical view of opening among Fig. 4 embodiment.
Among the figure: 1, preceding renovating; 2, renovate after; 3, loose-leaf; 4, hasp; 5, buckle; 6, press the Mus plate; 7, reed; 8, press the Mus plate to regulate bolt; 9, Mus cephalostat; 10, Mus diet hole; 11, hold-down nut; 12, lumbar injection hole; 13, lower limb holddown groove; 14, defecate groove; 15, fixing chute; 16, vertebral body base; 17, big rat holder; 18, base; 19, fall " T " cabinet frame; 20, slot; 21, support; 22, protractor; 23, pointer.
The specific embodiment
Embodiment 1: shown in Fig. 1,2,3,4, this device is that a cylindrical tube of being made by transparent material constitutes, and cylindrical shell is made up of openable upper and lower two parts, and the logical lateral loose-leaf 3 of upper and lower two parts connects.Cylindrical shell top be divided into again size renovate 1 before identical, after renovate 2 two parts, when opening, precedingly renovate 1, after renovate 2 and can turn up to 135 °.Before renovate 1, after renovate 2 and link to each other with the cylindrical shell lower part by loose-leaf 3 respectively, before renovate 1, after can forward and backward lid be connected into an integral body by intermediary hasp 4 between renovating 2, also can separately become independent two parts, thus select cylindrical shell top before renovate 1, after renovate 2 closed respectively or closed simultaneously.Cylindrical shell lower part holder with before renovate 1, after renovate 2 closed contact positions buckle 5 arranged, the upper and lower two parts of cylindrical shell can tighten upper and lower two parts locked by buckle 5 when closed, after the buckle closure, need to open big rat holder 17 by pressed by external force buckle 5.Renovate 2 inwalls behind the cylindrical shell and be connected with one and press Mus plate 6, the front of pressing Mus plate 6 by reed 7 with after renovate 2 inwalls and link to each other; Renovate 2 1/3rd places, middle back behind the cylindrical shell, have the pressure Mus plate that passes barrel to regulate bolt 8, scalable is pressed the position of Mus plate 6, makes to press fixedly rat tail back of Mus plate 6.Before renovate 1 correspondence the cylindrical shell lower part be connected with Mus cephalostat 9, Mus cephalostat 9 is vertebral body vacancy cylinder for the centre, and is thin before the vacancy, is connected with Mus diet hole 10, for the rats eating drinking-water of closing in big rat holder 17; After gradually thick, coincide with the Mus head shapes.Mus cephalostat 9 is fixed with cylindrical shell by the hold-down nut 11 of cylindrical shell side-lower, after unscrewing hold-down nut 11, can move forward and backward Mus cephalostat 9, to adapt to the not long rat of consubstantiality, hold-down nut 11 is fixedly moving forward and backward in the chute 15, with the fixing Mus cephalostat 9 of diverse location.There is elliptical aperture 12 at/3rd places, middle back of cylindrical shell lower part, are used for carrying out lumbar injection to experiment with rat, also can ventilate; The terminal both sides of cylindrical shell lower part have fixedly rat lower limb of lower limb holddown groove 13 respectively, are convenient to carry out the various operations at rat lower limb position; There is defecate groove 14 at the terminal middle part of cylindrical shell lower part, is beneficial to the rat defecation, simultaneously can be from here fixing rat root of the tail portion, be convenient to afterbody operations such as caudal vein puncture.Below the big rat holder 17 vertebral body base 16 is installed, can big rat holder 17 be installed in above the slot 20 above the support 21 by vertebral body base 16, vertebral body base 16 and slot 20 have good coincideing.Can arrange a plurality of slots 20 on the support 21, can set up a plurality of big rat holders 17, carry out the weightless operation of ground simulation of a plurality of rats simultaneously.Support 21 crossbearers are falling on " T " cabinet frame 19, and " T " cabinet frame 19 that falls at two ends is fixed on the base 18.Support 21 terminal with fall " T " cabinet frame 19 junctions protractor 22 arranged, the angle of inclination of big rat holder 17 can read out on protractor 22 by pointer 23; Be convenient to carry out the weightless research of ground simulation of aerospace medicine field differing tilt angles.Vertebral body base 16 and slot 20 are supporting to be fixed to big rat holder 17 on the support 21, and other structure that can reach fixed effect all can; If reed 7, pressing the Mus plate to regulate bolt 8, it's not true also Mus can be pressed onto in the holddown groove, but can't be applicable to the rat that various bodies are long, hold-down nut 11 and fixing chute 15 with reed 7, press Mus plate adjusting bolt 8 effects identical.Reed 7 can adopt " fixed pressure Mus plate " to substitute with pressing Mus plate adjusting bolt 8, will press Mus plate 6 to be fixed on " afterwards renovating " medial wall, omits this two structures, presses Mus plate 6 positions but can not regulate, and fixedly the effect of rat is also bad.Hold-down nut 11 can adopt the mode of " push and unlock " to fix.Vertebral body base 16 and slot 20 can adopt mode such as Magnet absorption to substitute, but fixed form is insecure." T " cabinet frame 19 that falls can adopt tripod to replace.
This utility model is not limited only to this embodiment 1, be connected the big rat holder 17 on the swinging mounting 21, can also be other big rat holders simple in structure, as long as it is connected and composed with renovating by holder, renovate on one side and be rotationally connected with holder, another side and holder snapping or clamping just can be closed rat very easily and be fixed in the stationary magazine creel.

Claims (8)

1. test with rat simulated weightlessness device, it is characterized in that: its big rat holder (17) is connected on the support (21) of rotation, support one end is fixed with protractor (22), the pointer (23) that rotation is arranged on the protractor (22), pointer (23) is fixed together with support (21) rotating shaft of rotating, its big rat holder (17) is connected and composed with renovating by holder, renovates on one side and is rotationally connected another side and holder snapping or clamping with holder.
2. experiment according to claim 1 rat simulated weightlessness device, it is characterized in that: described holder has Mus cephalostat (9), lumbar injection hole (12), lower limb holddown groove (13), defecate groove (14) in the past backward successively, and Mus diet hole (10) is arranged on the Mus cephalostat (9).
3. experiment according to claim 1 rat simulated weightlessness device is characterized in that: described renovating is connected with pressure Mus plate (6).
4. experiment according to claim 1 rat simulated weightlessness device, it is characterized in that: described renovating is the branch body structure, renovate before being divided into (1) and after renovate (2), preceding renovating (1) and after renovate (2) separate, preceding renovating (1) and after renovate the hasp (4) that connection is arranged between (2).
5. experiment according to claim 3 is characterized in that: reed (7) is arranged on the described pressure Mus plate (6) and press the Mus plate to regulate bolt (8) with rat simulated weightlessness device.
6. experiment according to claim 2 rat simulated weightlessness device, it is characterized in that: described Mus cephalostat (9) is the cylinder that there is vertebra cylinder cavity at the middle part, the diameter of vertebral body cavity progressively enlarges with the Mus head shapes after by forward direction and adapts, there is Mus raising hole (10) at cylinder front end center and is communicated with the vertebral body cavity, for the rats eating drinking-water of closing in big rat holder (17); Mus cephalostat (9) is fixedlyed connected with the fixedly chute (15) of holder by the hold-down nut (11) of cylindrical shell side-lower, after unscrewing hold-down nut (11), move forward and backward Mus cephalostat (9), to adapt to the not long rat of consubstantiality, hold-down nut (11) fixedly can move forward and backward in the chute (15).
7. experiment according to claim 1 rat simulated weightlessness device is characterized in that: slot (20) is arranged on the supporting plate of the support of described rotation (21), and slot (20) is plugged on the vertebral body base (16) of big rat holder (17).
8. experiment according to claim 1 is characterized in that: a plurality of slots (20) are arranged, a plurality of big rat holders (17) of pegging graft simultaneously on the supporting plate of described swinging mounting (21) with rat simulated weightlessness device.
CN2009203187391U 2009-12-28 2009-12-28 Rat weightlessness simulation device used for test Expired - Fee Related CN201578394U (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102129801A (en) * 2011-03-24 2011-07-20 宋昕宸 Intelligentized display device of simulated rat in simulated weightlessness condition
CN102657101A (en) * 2012-04-16 2012-09-12 中国人民解放军63919部队 Non-human primate test animal medium and long-term weightlessness simulation model device
CN103479447A (en) * 2013-09-30 2014-01-01 中国科学院深圳先进技术研究院 Anesthesia auxiliary device
CN106580511A (en) * 2016-12-12 2017-04-26 郑州大学第附属医院 Medicinal white mouse injection device
CN107711542A (en) * 2017-11-14 2018-02-23 天津开发区合普工贸有限公司 A kind of quick light poison experiment shield cage of toy
CN107890380A (en) * 2017-12-27 2018-04-10 上海市计划生育科学研究所 Animal experiment device
CN107928831A (en) * 2017-12-20 2018-04-20 中国科学院深圳先进技术研究院 Inject auxiliary fixing device
CN110584670A (en) * 2019-09-30 2019-12-20 北京锐视康科技发展有限公司 Medical imaging bearing cabin for experimental animals

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102129801A (en) * 2011-03-24 2011-07-20 宋昕宸 Intelligentized display device of simulated rat in simulated weightlessness condition
CN102657101A (en) * 2012-04-16 2012-09-12 中国人民解放军63919部队 Non-human primate test animal medium and long-term weightlessness simulation model device
CN103479447A (en) * 2013-09-30 2014-01-01 中国科学院深圳先进技术研究院 Anesthesia auxiliary device
CN103479447B (en) * 2013-09-30 2015-12-02 中国科学院深圳先进技术研究院 Anesthesia auxiliary device
CN106580511A (en) * 2016-12-12 2017-04-26 郑州大学第附属医院 Medicinal white mouse injection device
CN107711542A (en) * 2017-11-14 2018-02-23 天津开发区合普工贸有限公司 A kind of quick light poison experiment shield cage of toy
CN107928831A (en) * 2017-12-20 2018-04-20 中国科学院深圳先进技术研究院 Inject auxiliary fixing device
CN107890380A (en) * 2017-12-27 2018-04-10 上海市计划生育科学研究所 Animal experiment device
CN110584670A (en) * 2019-09-30 2019-12-20 北京锐视康科技发展有限公司 Medical imaging bearing cabin for experimental animals

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GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20100915

Termination date: 20121228