CN201564481U - Non-invasive blood glucose monitoring analyzer - Google Patents
Non-invasive blood glucose monitoring analyzer Download PDFInfo
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- CN201564481U CN201564481U CN2009202942986U CN200920294298U CN201564481U CN 201564481 U CN201564481 U CN 201564481U CN 2009202942986 U CN2009202942986 U CN 2009202942986U CN 200920294298 U CN200920294298 U CN 200920294298U CN 201564481 U CN201564481 U CN 201564481U
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Abstract
The utility model discloses a non-invasive blood glucose monitoring analyzer. A fixed wavelength light-emitting diode (LED) is used as a light source. Lights emitted from the light-emitting diode are focused by a biconvex mirror, exposed on a beam splitter and then divided into two beams: one of the beams is used as a reference optical path, of which the light intensity is detected by a silicon photoelectric diode detector, amplified by a front amplifier and sequentially transmitted to a data acquisition card to be used as a reference signal for the subsequent analysis of the light intensity; the other one is coupled into a multimode fiber, the surface of the skin being irradiated by a probe, subsequently the diffuse light being collected into the silicon optical diode detector by another optical fiber, also amplified by the front amplifier and sequentially transmitted to the data acquisition card to be used as an information signal for the subsequent analysis . The final data is processed by a non-invasive blood glucose monitoring analyzing software, thereby accomplishing the monitoring and the display of the blood glucose. The utility model has the advantages of compact size and portability; non-invasive monitoring and the convenience of daily detection and long-time monitoring; the system being flexible in monitoring and easy to update; low cost, the adaptation to household and the like.
Description
Technical field
This utility model belongs to the armarium technical field, particularly a kind of Woundless blood sugar check and analysis instrument of near-infrared diffuse reflectance technology.
Background technology
Diabetes are a kind of worldwide pandemics.(World Health Organization estimates that WHO) whole world has 1.8 hundred million people to suffer from diabetes at present, and this numeral will double above to the year two thousand thirty according to World Health Organization (WHO).Therefore prevention and treatment diabetes have very positive meaning.The easiest domestic blood sugar detecting method is to detect at person under inspection's finger tip blood sampling at present, though the self-detection method of this blood glucose has greatly improved the nursing level to the diabetes patient, but also there are some shortcomings in this detection method, such as its complex operation, causes pain to the patient; Finger tip is got blood the danger of infecting other disease, causes psychological pressure to the patient; Be unfavorable for the frequent detection of blood glucose, and the cost that detects is more high.The situation that some blood glucose are higher or lower than normal level may appear missing in the detection of the discrete time point that this frequency is not high simultaneously, thereby unfavorable to the nursing of diabetes.Therefore, press for and use the new non-invasive blood-sugar detecting instrument device of new method exploitation, adapt to the needs that diabetics detects frequency.
At present, the detection method of Woundless blood sugar mainly contains electrochemical process and optical method two big classes.Wherein, electrochemical process is also divided into the scope of Wicresoft sometimes, but it often has more intensive stimulation to skin.In the optical means, near infrared no-wound blood sugar test technology is because the advantage of himself is considered to one of a kind of Woundless blood sugar detection technique that the application future is arranged most; So at present, how to design a kind of employing near infrared no-wound blood sugar test technology, be suitable for the checkout equipment of practical operation simultaneously, becoming the present technique field has problem to be solved.
The utility model content
At there being wound to detect the blood glucose above shortcomings at present, and the present Research of Woundless blood sugar check and analysis, the purpose of this utility model is to provide a kind of noinvasive cheaply, measures the analytical tool of blood sugar for human body in real time, fast, it mainly is based on the principle that near-infrared diffuse reflection spectrum is analyzed, and is connected cost performance and the man-machine interaction performance of utilizing virtual instrument technique to improve instrument with home computer.
The purpose of this utility model is achieved in that a kind of Woundless blood sugar check and analysis instrument, comprises body, and its characteristics are that described body is provided with light source module, contact skin module, acquisition module; Described light source module comprise stand be installed, be arranged at the light emitting diode installed on the stand, corresponding biconvex lens and the beam splitter that is arranged at light emitting diode the place ahead successively; Described contact skin module comprises receiving terminal optical fiber head, probe, transmitting terminal optical fiber head, probe is connected with the transmitting terminal optical fiber head with the receiving terminal optical fiber head respectively by two root multimode fibers, the corresponding setting of described receiving terminal optical fiber head with beam splitter, be used for a branch of multimode fibre that is optically coupled into that beam splitter is told, light reaches probe through multimode fibre, through probe irradiation skin surface, skin surface diffuses and reaches the transmitting terminal optical fiber head through probe and another multimode fibre; Described acquisition module comprises reference signal collection circuit, information signal is gathered circuit and pci data capture card, reference signal is gathered circuit and is gathered circuit by silicon photodiode detector that is connected successively and preamplifier formation with information signal, reference signal is gathered the corresponding setting with beam splitter of silicon photodiode detector of circuit, another Shu Guang that beam splitter is told is gathered the silicon photodiode detector collection of circuit and arrive the pci data capture card after preamplifier amplifies by reference signal, information signal is gathered the corresponding setting with the transmitting terminal optical fiber head of silicon photodiode detector of circuit, and skin surface diffuses and arrives the silicon photodiode detector of information signal collection circuit and arrive the pci data capture card after preamplifier amplifies through the transmitting terminal optical fiber head; Also include the analysis display module, analyze display module and is connected, be used to receive two groups of data that the pci data capture card sends and finish and contrast processing and display process result with the pci data capture card.
More particularly, the Woundless blood sugar check and analysis instrument that this utility model is related is made up of light source module, contact skin module, signal acquisition module, analysis display module.This system uses the standing wave long hair optical diode (LED) that is fixed on the light emitting diode stand as light source.The light that light emitting diode sends is through the effect of converging of biconvex mirror, shine on the beam splitter, light is divided into two bundles: a branch of conduct is with reference to light path, detect its light intensity by silicon photodiode detector, after the preamplifier amplification, to the pci data capture card, as the reference signal of follow-up light intensity analysis; Another Shu Guang is coupled in the multimode fibre by the receiving terminal optical fiber head, through probe irradiation skin surface, then by another root multimode fiber collect irreflexive light through the transmitting terminal optical fiber head to another silicon photodiode detector, same through the preamplifier amplification, to the pci data capture card, as the information signal of subsequent analysis.Last two paths of signals enters computer by the PCI connection cord, is handled by the analysis display module that is arranged in the computer.In analyser, that the Lights section adopts is the long LED of four standing waves, and the wave band at its wavelength place is 500～1000nm, and adopts the constant-current source power drives to guarantee stability of light source.Because the requirement of the optical system of above-mentioned light source and detection, all optical elements require to have good optical property at this specific wave band.
This utility model is based on near-infrared diffuse reflectance spectrometry.Near-infrared diffuse reflectance spectrometry measuring blood concentration utilizes the specificity of the glucose absorption coefficient of light to carry out based on Lambert-Beer's law and light scattering theory.By the glucose sum of fundamental frequencies of detection near infrared region distribution and the spectrum signal that diffuses of frequency multiplication section, then the signal that collects is carried out mathematical modeling, according to the near-infrared diffuse reflectance blood sugar test model of setting up, finally obtain the blood sugar concentration of user.Wherein, the wave band at the fixed point wavelength place that this utility model adopted is at 500～1000nm, carries out communication by PCI communication cable RC68-68, data collecting card PCI-6221 and pci bus and computer respectively after the signal of telecommunication that is obtained by optical detector amplifies through preamplifier.On windows platform, software by the VC++6.0 establishment, ratio according to information light path and reference path two-way light intensity signal converts the diffuse-reflectance absorbance to, then by human detection to blood sugar concentration information set up mathematical model, finally finish analyzing and testing function by detecting light intensity to blood glucose according to this model.
The blood glucose noinvasive check and analysis instrument that this utility model is related has following advantage:
(1) blood sugar test is non-invasive, can realize the frequent detection and the long time monitoring of blood glucose; (2) volume is small and exquisite, is convenient for carrying, and is fit to the daily monitoring of diabetics; (3) simple to operate, need not consumptive material, it is lower to detect cost; (4) detection speed is very fast, and the serious detection of avoiding other Woundless blood sugar detection methods to occur postpones; (5) software and hardware separation make things convenient for the upgrading of system; (6) home computer is universal day by day at present, select the platform of home computer, and utilize virtual instrument technique, realize more hardware capability by software as signal processing, information demonstration and the information management of system, reduce the cost of system, increased the motility of system; (7) software can be used as the stand-alone program use, is used for medical record management, patient information inquiry; (8) the hardware light path system is simple in structure, and cost is lower, has increased the stability of system simultaneously; (9) utilize multifunctional data acquiring equipment PCI-6221, make system realize better calibration, thereby reach higher precision.
Description of drawings
Fig. 1 is this utility model structural representation;
Fig. 2 makes body when specifically implementing the cabinet shape and light source module, contact skin module, acquisition module is integrated in surface structure sketch map behind the cabinet inside.
Wherein: 4 for analyzing display module, and 5 for installing stand, and 6 is light emitting diode, 7 is biconvex mirror, and 8 is beam splitter, and 9 and 15 is silicon photodiode detector, 10 and 16 is preamplifier, and 11 is the receiving terminal optical fiber head, and 14 is the transmitting terminal optical fiber head, 12 is multimode fibre, 13 are probe, and 17 is the pci data capture card, and 18 is the PCI connection cord, 19 is computer, and 20 is body.
The specific embodiment
The technical solution of the utility model is further specified as follows below in conjunction with drawings and Examples:
During concrete enforcement, as shown in Figure 1, a kind of Woundless blood sugar check and analysis instrument comprises body 20, and described body 20 is provided with light source module, contact skin module, acquisition module; Described light source module comprise stand 5 be installed, be arranged at the light emitting diode 6 installed on the stand 5, corresponding biconvex lens 7 and the beam splitter 8 that is arranged at light emitting diode 6 the place aheads successively; Described contact skin module comprises receiving terminal optical fiber head 11, probe 13, transmitting terminal optical fiber head 14, probe 13 is connected with transmitting terminal optical fiber head 14 with receiving terminal optical fiber head 11 respectively by two root multimode fibers 12, described receiving terminal optical fiber head 11 and beam splitter 8 corresponding settings, be used for a branch of multimode fibre that is optically coupled into that beam splitter 8 is told, light reaches probe 13 through multimode fibre, through pop one's head in 13 the irradiation skin surfaces, skin surface diffuse through pop one's head in 13 and another multimode fibre reach transmitting terminal optical fiber head 14; Described acquisition module comprises reference signal collection circuit, information signal is gathered circuit and pci data capture card 17, reference signal is gathered circuit and is gathered circuit by the silicon photodiode detector 9 that is connected successively with information signal, 15 and preamplifier 10,16 constitute, reference signal is gathered the silicon photodiode detector 9 and beam splitter 8 corresponding settings of circuit, another Shu Guang that beam splitter 8 is told is gathered silicon photodiode detector 9 collections of circuit and arrive pci data capture card 17 after preamplifier 10 amplifies by reference signal, information signal is gathered the silicon photodiode detector 15 and the 14 corresponding settings of transmitting terminal optical fiber head of circuit, and skin surface diffuses and arrives the silicon photodiode detector 15 of information signal collection circuit and arrive pci data capture card 17 after preamplifier 16 amplifies through transmitting terminal optical fiber head 14; Also include and analyze display module 4, this analysis display module is separately set in the computer 19, computer 19 is connected with pci data capture card 17 by PCI connection cord 18, is used to receive two groups of data that pci data capture card 17 sends and finishes contrast processing and display process result.
More particularly, allomeric function of the present utility model is made up of following module: light source module, and comprise light emitting diode (LED) 6 and stand 5 is installed, finish the biconvex lens 7 that converges the light function, finish the beam splitter 8 of beam split function; The contact skin module comprises that mainly light source is derived and two root multimode fibers 12 of collection diffuse-reflectance light intensity, probe 13; Signal acquisition module 3, comprise the collection of reference signal and information signal two paths of signals, structure is similar substantially, by the silicon photodiode detector 9 and 15 with photoelectric sensing function, the preamplifier 10 and 16 of enlarging function, and the pci data capture card 17 of signals collecting function is formed; Analyzing display module 4, mainly is to finish the processing of signal data and the Presentation Function of end product on computers.The whole system piecemeal makes up, and each module can be carried out the installation and the debugging of single module, has improved the efficient of system building and has made things convenient for the follow-up system troubleshooting of faults.Light emitting diode during enforcement (LED) 6 adopt wave bands at the light emitting diode of 500～1000nm as light source, light converged by biconvex mirror 7 before beam splitter 8 beam splitting; On reference signal path, detect its light intensity, after amplifying through preamplifier 10,, obtain required reference signal to pci data capture card 17 by silicon photodiode detector 9; On the detection signal road, optical fiber head couples light into multimode fibre 12, arrive probe 13 by multimode fibre, another root multimode fiber is collected the diffuse-reflectance light intensity signal that has carried blood sugar concentration information and is arrived silicon photodiode detector 15, equally voltage signal is amplified through preamplifier 16, to pci data capture card 17, obtain the required information signal that carries the blood sugar concentration feature; The data that collect on the last capture card are carried out communication by PCI communication cable 18 via pci bus and computer 19.
As shown in Figure 2, this utility model can be that light source module, contact skin module, signal acquisition module all are incorporated on the body 20 when implementing, body 20 can be used as cabinet shape, make light source module, contact skin module, signal acquisition module all be integrated into cabinet inside, to analyze display module and be arranged on separately on the computer 19, and can make it easy to like this carry.Only stay several and extraneous window of getting in touch on the surface of cabinet, comprise on and off switch, probe window and the communication cable that is connected with computer.By communication cable the signal that collects is passed to computer and carry out processes and displays, finish the blood sugar test function.Also can be to be integrated in the analysis display module on the body together and a display screen is set analysis result is shown when certainly, specifically implementing.
During use,, PCI communication cable 18 is received on the computer 19, and opened on and off switch on the body, need preheating 2～3min this body energized.The forearm of human body is placed on the probe window (groove of arm placement location can be set on the body) of body, and near-infrared luminous diode is luminous in turn.On two light paths, there is optical signalling to convert optical signalling to the signal of telecommunication through silicon photodiode detector 9,15, pass through the amplification of preamplifier 10,16 again, make small-signal to detect better, PCI capture card 17 adopts the dual pathways to gather two paths of data, communicate through communication cable 18 and computer 19, last Woundless blood sugar analysis software utilizes the near-infrared analysis mathematical model that data are handled, realize the demonstration of blood sugar concentration, functions such as the preservation of patient's relevant information and reproduction.
Computer software of the present utility model partly works in the Windows operating system platform of Microsoft, adopts the programming of visual c++ 6.0 programming languages, can work under the operating system platform of Windows Vista and later release at Windows 2000/XP/NT.As software section of the present utility model, allow it to break away from hardware components independent operating of the present utility model.
Claims (2)
1. a Woundless blood sugar check and analysis instrument comprises body, and it is characterized in that: described body is provided with light source module, contact skin module and acquisition module;
Described light source module comprise stand be installed, be arranged at the light emitting diode installed on the stand, corresponding biconvex lens and the beam splitter that is arranged at light emitting diode the place ahead successively;
Described contact skin module comprises receiving terminal optical fiber head, probe and transmitting terminal optical fiber head, and probe is connected with the transmitting terminal optical fiber head with the receiving terminal optical fiber head respectively by two root multimode fibers; The corresponding setting of beam splitter of described receiving terminal optical fiber head and light source module, be used for a branch of multimode fibre that is optically coupled into that beam splitter is told, light reaches probe through multimode fibre, and through probe irradiation skin surface, skin surface diffuses and reaches the transmitting terminal optical fiber head through probe and another multimode fibre;
Described acquisition module comprises that reference signal is gathered circuit, information signal is gathered circuit and pci data capture card, reference signal is gathered circuit and is gathered circuit by silicon photodiode detector that is connected successively and preamplifier formation with information signal, reference signal is gathered the silicon photodiode detector of circuit and the corresponding setting of beam splitter of light source module, the silicon photodiode detector collection that another Shu Guang that beam splitter is told is gathered circuit by reference signal, and after preamplifier amplifies, arrive the pci data capture card; Information signal is gathered the corresponding setting with the transmitting terminal optical fiber head of silicon photodiode detector of circuit, and skin surface diffuses and arrives the silicon photodiode detector of information signal collection circuit and arrive the pci data capture card after preamplifier amplifies through the transmitting terminal optical fiber head;
Also include the analysis display module, analyze display module and is connected, be used to receive two groups of data that the pci data capture card sends and finish and contrast processing and display process result with the pci data capture card.
2. Woundless blood sugar check and analysis instrument according to claim 1 is characterized in that: it is the light emitting diode of 500～1000nm that light emitting diode adopts wavelength.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009202942986U CN201564481U (en) | 2009-12-31 | 2009-12-31 | Non-invasive blood glucose monitoring analyzer |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2009202942986U CN201564481U (en) | 2009-12-31 | 2009-12-31 | Non-invasive blood glucose monitoring analyzer |
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| CN201564481U true CN201564481U (en) | 2010-09-01 |
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| CN2009202942986U Expired - Fee Related CN201564481U (en) | 2009-12-31 | 2009-12-31 | Non-invasive blood glucose monitoring analyzer |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103260515A (en) * | 2010-10-14 | 2013-08-21 | 株式会社日立制作所 | Equipment for in vivo data acquisition and analysis |
| CN104013411A (en) * | 2014-05-15 | 2014-09-03 | 哈尔滨工业大学 | Transmission type noninvasive blood sugar detection device |
| ES2537051A1 (en) * | 2014-12-29 | 2015-06-01 | Dispositivos No Invasivos Para Diagnosis, S.L. | Quantification system of blood glucose levels (Machine-translation by Google Translate, not legally binding) |
| CN105266824A (en) * | 2011-04-29 | 2016-01-27 | 台医光电科技股份有限公司 | Method for non-invasive blood glucose monitoring and method for analysing biological molecule |
| CN105942982A (en) * | 2016-06-01 | 2016-09-21 | 何雷 | Tumor predictor based on dynamic spectra |
| CN106308814A (en) * | 2016-08-09 | 2017-01-11 | 上海润寿智能科技有限公司 | Blood sugar non-invasive detection instrument based on near infrared spectrum analysis and realization method thereof |
| CN108226049A (en) * | 2018-01-16 | 2018-06-29 | 哈尔滨学院 | System for detecting blood sugar and detection method |
| CN109330608A (en) * | 2018-08-14 | 2019-02-15 | 林彧宁 | Blood sugar measuring method and device |
-
2009
- 2009-12-31 CN CN2009202942986U patent/CN201564481U/en not_active Expired - Fee Related
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103260515A (en) * | 2010-10-14 | 2013-08-21 | 株式会社日立制作所 | Equipment for in vivo data acquisition and analysis |
| CN103260515B (en) * | 2010-10-14 | 2015-04-22 | 株式会社日立制作所 | Equipment for in vivo data acquisition and analysis |
| CN105266824A (en) * | 2011-04-29 | 2016-01-27 | 台医光电科技股份有限公司 | Method for non-invasive blood glucose monitoring and method for analysing biological molecule |
| CN104013411A (en) * | 2014-05-15 | 2014-09-03 | 哈尔滨工业大学 | Transmission type noninvasive blood sugar detection device |
| ES2537051A1 (en) * | 2014-12-29 | 2015-06-01 | Dispositivos No Invasivos Para Diagnosis, S.L. | Quantification system of blood glucose levels (Machine-translation by Google Translate, not legally binding) |
| WO2016107949A1 (en) * | 2014-12-29 | 2016-07-07 | Dispositivos No Invasivos Para Diagnosis, S.L. | System for quantifying blood glucose levels |
| CN105942982A (en) * | 2016-06-01 | 2016-09-21 | 何雷 | Tumor predictor based on dynamic spectra |
| CN105942982B (en) * | 2016-06-01 | 2019-02-15 | 何雷 | A kind of tumour prediction instrument based on dynamic spectrum |
| CN106308814A (en) * | 2016-08-09 | 2017-01-11 | 上海润寿智能科技有限公司 | Blood sugar non-invasive detection instrument based on near infrared spectrum analysis and realization method thereof |
| CN108226049A (en) * | 2018-01-16 | 2018-06-29 | 哈尔滨学院 | System for detecting blood sugar and detection method |
| CN109330608A (en) * | 2018-08-14 | 2019-02-15 | 林彧宁 | Blood sugar measuring method and device |
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| C14 | Grant of patent or utility model | ||
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20100901 Termination date: 20131231 |