CN201473541U - Sperm-uterine neck mucus interaction capillary test device - Google Patents
Sperm-uterine neck mucus interaction capillary test device Download PDFInfo
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- CN201473541U CN201473541U CN2009201348172U CN200920134817U CN201473541U CN 201473541 U CN201473541 U CN 201473541U CN 2009201348172 U CN2009201348172 U CN 2009201348172U CN 200920134817 U CN200920134817 U CN 200920134817U CN 201473541 U CN201473541 U CN 201473541U
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- seminal vesicle
- kapillary
- sperm
- capillary
- interactional
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Abstract
The utility model discloses a sperm-uterine neck mucus interaction capillary test device which is characterized in that the capillary test device comprises a penetrating plate (10) with the upper surface being step-shaped; the lower upper surface (11) of the penetrating plate is provided with at least one seminal vesicle laying position (12); the higher upper surface (13) of the penetrating plate is provided with a capillary laying position (14) on a straight line of the corresponding seminal vesicle laying position, thus leading the capillary to extend into a seminal vesicle horizontally; the penetrating plate is provided with scale line (15); the scale line is vertical to the direction from the seminal vesicle laying position to the corresponding capillary laying position; and the marks of the scale line are distributed at intervals from the seminal vesicle laying position to the capillary laying position. The test device is convenient for quantified observation of test results, and has high accuracy and good repeatability; and the seminal vesicle and the capillary can be installed and replaced, thus being convenient for use.
Description
Technical field
The utility model relates to the reproductive medicine testing apparatus, particularly relates to the interactional external capillary test devices of a kind of sperm-cervical mucus.
Background technology
The interaction of sperm and female genital tract secretory product is most important for the existence and the function of sperm.Comprehensive inspection of infertility must be the interaction of sperm-cervical mucus assessment as an important indicator.Sperm-cervical mucus interacts and tests the indication that can be used for infertility etiological analysis and artificial insemination or other form supplementary reproductions.But in the prior art, sperm-cervical mucus interacts to test and normally carries out on common slide glass, does not have scale on the slide glass, can't accomplish that quantification detects, make existing sperm-cervical mucus interact and test to have very strong subjectivity, influenced the accuracy and the repeatability of test.
Summary of the invention
The technical problems to be solved in the utility model provides a kind of sperm-special-purpose capillary test devices of cervical mucus interaction test, and this device is convenient in test carry out quantification observation, accuracy height.
For solving the problems of the technologies described above, the utility model provides a kind of sperm-cervical mucus interactional capillary test devices, it is characterized in that, comprise that a upper surface is step-like take-through plate, at least one seminal vesicle is set on the low upper surface of described take-through plate places the position, then be provided with on the described upper surface that penetrates plate hight and corresponding described seminal vesicle is placed position kapillary point-blank and placed the position, can make the capillary energy level stretch in the described seminal vesicle; Described take-through plate is provided with the size scale line, and described size scale line is placed the direction of position perpendicular to put the kapillary that is set to correspondence from seminal vesicle, and described size scale line is spaced apart to kapillary placement position direction from seminal vesicle placement position.
Around described each seminal vesicle placement position, its excess-three face except the side of placing the position in the face of kapillary is respectively equipped with and is the localized projection of seminal vesicle.
It is to be the localized locating slot of kapillary that described each kapillary is placed the position.
Described size scale line runs through the width of whole take-through plate; The dimensioning scope is 0~5cm; Its zero graduation line is in seminal vesicle is placed the position scope; The scale marks at its 1cm and 4.5cm place is different with all the other scale marks colors.
This device also comprises the removable seminal vesicle that described seminal vesicle is placed the position that is loaded on.
Described seminal vesicle is one the one open semi-cylindrical utricule of end, and the bottom surface that contacts with take-through plate is the plane, and this bottom surface is provided with non-setting adhesive; The height of seminal vesicle is greater than the difference of altitude between the high upper surface of take-through plate and the low upper surface.
This capillary test devices also comprises the removable kapillary that described kapillary is placed the position that is loaded on.
Described seminal vesicle is made for the transparent plastics material; Described kapillary is the flat glass kapillary.
Described flat glass length specification capillaceous is 60mm, and width is 3mm, and tranverse sectional thickness is 0.3mm; Described take-through plate is that plastic material is made.
It is three or four that are arranged in parallel that described seminal vesicle is placed the position, and it is to place three or four one to one of positions with described seminal vesicle that described kapillary is placed the position.
Capillary test is a kind of semiquantitative external test method, is used to assess the ability that sperm penetrates the cervical mucus level.When Huhner's test preliminary examination detects when unusual, need carry out revision test with in vitro testss such as kapillaries, further to determine the penetrativity of sperm.If the sperm penetration power is relatively poor, can also adopt donor cervical mucus and donor sperm to carry out cross matching, actually or analyze the results abnormity that the sperm cervical mucus causes.The interactional capillary test devices of sperm-cervical mucus of the present utility model can very conveniently be carried out capillary test exactly, take-through plate is provided with seminal vesicle and kapillary is placed the position, can load onto seminal vesicle and kapillary in use, horizontal with capillary tube is stretched in the seminal vesicle, make sperm and cervical mucus interact, being arranged so that of take-through plate high scale line observes convenient, can obtain a plurality of test parameters easily, and test-results more accurately and reliably, is beneficial to sperm and cervical mucus that evaluation is more objectively detected.More convenient to use and needn't separately and exclusively prepare seminal vesicle and kapillary for ease of the user, the utility model also provides supporting removable seminal vesicle and kapillary, and this take-through plate is reusable, and seminal vesicle and kapillary are disposable product.
Description of drawings
Below in conjunction with the drawings and specific embodiments the utility model is described in further detail.
Fig. 1 is the interactional capillary test devices of sperm-cervical mucus of the utility model embodiment 1.
Fig. 2 is the interactional capillary test devices of sperm-cervical mucus of the utility model embodiment 2.
Fig. 3 is a seminal vesicle profile stereographic map of the present utility model.
Embodiment
Embodiment 1
As shown in Figure 1, the interactional capillary test devices of sperm-cervical mucus comprises that a upper surface is step-like take-through plate 10, it is made by plastic material, its ladder forms a low upper surface 11 and a high upper surface 13, on described low upper surface 11, be provided with three seminal vesicles side by side and place position 12, on high upper surface 13, then be provided with three parallel kapillaries side by side and place position 14, it is corresponding one by one with seminal vesicle placement position 12 that described kapillary is placed position 14, every pair of kapillary is placed position 14 and is placed position 12 point-blank with seminal vesicle, on kapillary placement position, placed kapillary, seminal vesicle is placed on the position and has been laid seminal vesicle, can make horizontal with capillary tube stretch in the seminal vesicle (seeing also Fig. 2); Around described each seminal vesicle placement position 12, its excess-three face except the side of placing the position in the face of kapillary is respectively equipped with and is seminal vesicle localized protruding 121, it is to be the localized locating slot of kapillary that described each kapillary is placed 14 of positions, and this locating slot is formed by the plates 141 of two protrusions that are positioned at the kapillary two sides.
Described take-through plate 10 is provided with size scale line 15, be marked with 0,1,2,3,4 among the figure, 5cm promptly be, that also have that a scale marks represents with the centre of 5cm is 4.5cm 4, and the dimensioning scope is 0~5cm, and its zero graduation line is in seminal vesicle is placed the scope of position 12; These size scale lines are set to the direction that kapillary is placed the position perpendicular to putting from seminal vesicle, and through whole take-through plate width, and described size scale line is spaced apart to kapillary placement position direction from seminal vesicle placement position.In order to be convenient in test observation, the scale marks at its 1cm and 4.5cm place is different with all the other scale marks colors, the general redness that adopts, and all the other scale markss employings are blue.
This take-through plate 10 is reusable, then loads onto seminal vesicle 20 and kapillary 30 when needs are tested, and this embodiment is not equipped with seminal vesicle and capillaceous, and seminal vesicle and state capillaceous are housed can be with reference to shown in Figure 2.The interactional capillary test devices of this sperm-cervical mucus also can comprise the seminal vesicle 20 and the kapillary 30 of detachable replacing, and described seminal vesicle 20 is removable to be loaded on that described seminal vesicle is placed position 12 and kapillary is removable is loaded on described kapillary and places position 14.
Described seminal vesicle 20 is made for the transparent plastics material, it is one the one open semi-cylindrical utricule of end, as shown in Figure 3, its bottom surface that contacts with take-through plate 10 is the plane, this bottom surface is provided with double-sided adhesive, and the shape of non-setting adhesive is consistent with the seminal vesicle bottom shape, and the overlay paper that tears non-setting adhesive in the time of use can be pasted on seminal vesicle take-through plate 10, locate with localized protruding 121 respectively for three, the opening end of seminal vesicle is placed the position towards kapillary; The height of seminal vesicle is greater than the difference of altitude between the high upper surface 13 of take-through plate and the low upper surface 11, and will guarantee that the capillary energy level stretches in the described seminal vesicle; For ease of observing, described kapillary 30 is the flat glass kapillary, and its preferred length specification is 60mm, and width is 3mm, and tranverse sectional thickness is 0.3mm.
Using method of the present utility model is as follows:
Fresh semen is packed in the seminal vesicle, can not overfill (in order to avoid seminal fluid overflows after inserting kapillary), note simultaneously avoiding having in the capsule and produce bubble and produce; Tear seminal vesicle bottom non-setting adhesive overlay paper off, the seminal vesicle that the seminal vesicle that seminal fluid is housed is accurately sticked on take-through plate is placed the position; Cervical mucus is injected in the kapillary, and that end that immerses seminal fluid is full of cervical mucus fully, and guarantees no bubble in the whole kapillary, and seals the outer end capillaceous (that end of non-immersion seminal fluid) that has been full of cervical mucus to seal mud 40; With kapillary not sealing end insert in the seminal vesicle that seminal fluid is housed be fixed on the take-through plate, the kapillary port immerses in the seminal fluid fully and aims at " 0 " scale marks (as shown in Figure 2) on the take-through plate, the kapillary that kapillary is lain in naturally take-through plate is placed in the position 14, promptly with in the spacing locating slot of a pair of plates 141; And on kapillary 1.0 and the 4.5cm position serve as a mark; Gently whole device level is put into wet box, keeping its wettability, and prevented seminal fluid and cervical mucus drying.Hatched 2-24 hour for 37 ℃; Respectively at 2 hours and 24 hours kapillary is placed under the microscope low-power field (LPF:1010 * 10), the viewing distance kapillary immerses the sperm quantity of seminal fluid end 1.0 and 4.5cm two place's mark positions, counts the sperm quantity and the calculating mean value of adjacent 5 low-power fields.Measurement is preferably in 37 ℃ of environment to be carried out.Read the sperm number of migration distance, penetration density, migration minimizing and the propulsion of sperm after 2 hours.In order to observe the performance of sperm propulsion, answer the rechecking kapillary after 24 hours.Can assess following variable after 2 hours: (1) migration distance, refer to from the capillary end that immerses the seminal fluid reservoir to pipe distance the top sperm; (2) penetration density is measured at the capillary end 1cm in immersion seminal fluid capsule and two some places of 4.5cm.Sperm mean number decision by observed each range points under every low-power field (LPF:10 * 10).Obtain mean number by counting adjacent 5 low-power fields.(3) migration reduces, and the penetration density when 4.5cm is described reduces during than 1cm.(4) time length of preceding motion, be determined at the sperm that occurs propulsion in the cervical mucus in 2 hours and 24 hours.
As seen, the interactional capillary test devices of sperm-cervical mucus of the present utility model is easy to use, and observation is convenient, can obtain a plurality of test parameters easily, and the result is more accurate, is beneficial to and assesses sperm and cervical mucus more objectively.
The interactional capillary test devices of sperm-cervical mucus as shown in Figure 2 is equipped with four parallel seminal vesicle 20 and four kapillaries 30 one to one with it side by side.All the other features are with embodiment 1.
Claims (10)
1. interactional capillary test devices of sperm-cervical mucus, it is characterized in that, comprise that a upper surface is step-like take-through plate (10), at least one seminal vesicle is set on the upper surface that described take-through plate is low (11) places position (12), then be provided with on the described upper surface (13) that penetrates plate hight and corresponding described seminal vesicle is placed position kapillary point-blank and placed position (14), can make the capillary energy level stretch in the described seminal vesicle; Described take-through plate is provided with size scale line (15), and described size scale line is placed the direction of position perpendicular to put the kapillary that is set to correspondence from seminal vesicle, and described size scale line is spaced apart to kapillary placement position direction from seminal vesicle placement position.
2. the interactional capillary test devices of sperm-cervical mucus according to claim 1, it is characterized in that, around described each seminal vesicle placement position (12), its excess-three face except the side of placing position (14) in the face of kapillary is respectively equipped with and is the localized projection of seminal vesicle (121).
3. the interactional capillary test devices of sperm-cervical mucus according to claim 1 is characterized in that, it is to be the localized locating slot of kapillary that described each kapillary is placed position (14).
4. the interactional capillary test devices of sperm-cervical mucus according to claim 1 is characterized in that described size scale line (15) runs through the width of whole take-through plate (10); The dimensioning scope is 0~5cm; Its zero graduation line is in seminal vesicle is placed position (12) scope; The scale marks at its 1cm and 4.5cm place is different with all the other scale marks colors.
5. the interactional capillary test devices of sperm-cervical mucus according to claim 1 is characterized in that, this device also comprises the removable seminal vesicle (20) that described seminal vesicle is placed position (12) that is loaded on.
6. the interactional capillary test devices of sperm-cervical mucus according to claim 5, it is characterized in that, described seminal vesicle (20) is one the one open semi-cylindrical utricule of end, and the bottom surface that contacts with take-through plate (10) is the plane, and this bottom surface is provided with non-setting adhesive; The height of seminal vesicle is greater than the difference of altitude between the high upper surface of take-through plate and the low upper surface.
7. according to the interactional capillary test devices of each described sperm-cervical mucus of claim 1-6, it is characterized in that described capillary test devices also comprises the removable kapillary (30) that described kapillary is placed position (14) that is loaded on.
8. the interactional capillary test devices of sperm-cervical mucus according to claim 7 is characterized in that described seminal vesicle is made for the transparent plastics material; Described kapillary (30) is the flat glass kapillary.
9. the interactional capillary test devices of sperm-cervical mucus according to claim 8 is characterized in that described flat glass length specification capillaceous is 60mm, and width is 3mm, and tranverse sectional thickness is 0.3mm; Described take-through plate is that plastic material is made.
10. the interactional capillary test devices of sperm-cervical mucus according to claim 1, it is characterized in that, it is three or four that are arranged in parallel that described seminal vesicle is placed position (12), and it is to place three or four one to one of positions with described seminal vesicle that described kapillary is placed position (14).
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CN2009201348172U CN201473541U (en) | 2009-08-14 | 2009-08-14 | Sperm-uterine neck mucus interaction capillary test device |
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CN2009201348172U CN201473541U (en) | 2009-08-14 | 2009-08-14 | Sperm-uterine neck mucus interaction capillary test device |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108709827A (en) * | 2018-08-13 | 2018-10-26 | 上海市计划生育科学研究所 | A kind of gel barrier effect detection device and detection method |
CN113528310A (en) * | 2021-06-16 | 2021-10-22 | 复旦大学 | Bionic micro-fluidic chip for simulating cervical microenvironment and preparation method thereof |
-
2009
- 2009-08-14 CN CN2009201348172U patent/CN201473541U/en not_active Expired - Lifetime
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108709827A (en) * | 2018-08-13 | 2018-10-26 | 上海市计划生育科学研究所 | A kind of gel barrier effect detection device and detection method |
CN113528310A (en) * | 2021-06-16 | 2021-10-22 | 复旦大学 | Bionic micro-fluidic chip for simulating cervical microenvironment and preparation method thereof |
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Granted publication date: 20100519 |