CN201353311Y - Multifunctional hyperthermic perfusion machine - Google Patents
Multifunctional hyperthermic perfusion machine Download PDFInfo
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- CN201353311Y CN201353311Y CNU2009200026699U CN200920002669U CN201353311Y CN 201353311 Y CN201353311 Y CN 201353311Y CN U2009200026699 U CNU2009200026699 U CN U2009200026699U CN 200920002669 U CN200920002669 U CN 200920002669U CN 201353311 Y CN201353311 Y CN 201353311Y
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- perfusion
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- effusion
- ultrafilter
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Abstract
The utility model discloses a multifunctional hyperthermic perfusion machine, which is used for chemotherapy of abdominal cavity (thoracic cavity) malignant tumor and concentration and re-infusion treatment of large quantities of ascites. The multifunctional hyperthermic perfusion machine comprises a pipeline system, a perfusion power pump, a controllable thermostatic microwave heating bin, a heat exchanger, a computer temperature controller and the like. When a patient has intracavity malignant effusion, the multifunctional hyperthermic perfusion machine can pump the malignant effusion, thermostatically heats the malignant effusion to 43-45 DEG C, and then transfuses the malignant effusion into the abdominal cavity or the thoracic cavity after combining the malignant effusion with anticarcinogen and performing hypoosmolality processing, thereby effectively stopping tumor transferring and recidivation, and removing intractable malignant effusion which is difficult to control. Simultaneously, the multifunctional hyperthermic perfusion machine is equipped with a capillary vessel ultrafilter, a negative pressure suction pump and the like, organically combines hyperthermic perfusion chemotherapy with ascites ultrafilter concentration and re-infusion treatment, can not only treat malignant effusion but perform concentration and re-infusion treatment to large quantities of ascites caused by hypoproteinemia such as liver cirrhosis, is multifunctional, and can rapidly remove malignant coelom effusion caused by different diseases.
Description
Technical field:
This utility model relates to a kind of medical treatment device, particularly relates to the chemotherapy of splanchnocoel malignant tumor and the medical treatment device of a large amount of concentrated ascites reinfusion treatments.
Background technology:
The easy intracavity of splanchnocoel malignant tumor shifts, recurrence, often causes that the recidivist is 50% in the general postoperative of a large amount of carcinous intracavity hydrops, especially human primary gastrointestinal cancers 1 year, be 80% in 2 years, up to 90%, be the topmost cause of death in 4 years, still do not have effective controlling way so far.The blue or green professor of the attached Chen Jun of institute of Chinese Medical Sciences University one is before the gastric cancer radical cure finishes to close the abdominal cavity, and only with 43 ℃ of warm saline 4000ml immersions 10 minutes, what just make that 5 years survival rates of middle and advanced stage postoperative gastric cancer never soak 23.1% rises to 43.3% after the immersion.Though this method effect is comparatively obvious, only be in operation process, to carry out.
Summary of the invention:
This utility model is designed the hot perfusion unit of a kind of novel multifunction exactly, both can be used to treat a large amount of cancerous effusions of intracavity, promptly forms artificial ascites with the perfusion normal saline and reaches warm-heat perfusion and treat and prevent and treat the early stage transfer and relapse of intracavitary neoplasm; Can concentrate adoptive therapy to a large amount of ascites such as liver cirrhosis again.
This utility model is achieved in that according to tumor cell different with Normocellular temperature tolerance, normal cell can tolerate 47 ℃ of high temperature, and tumor cell irreversible death will occur at 43 ℃, from Fig. 3 " curve chart of tumor survival rate-heating-up temperature " as can be seen, tumor cell is heated between 43 ℃-44 ℃, and survival rate obviously descends along with the growth of heat time heating time.The multifunctional heating perfusion unit that goes out of principle design can be used to treat a large amount of cancerous effusions of intracavity thus, or the control intracavitary neoplasm recurs in early days.This utility model is made up of import and export closed cycle tubing, heat exchanger, controllable constant-temperature microwave heating storehouse, perfusion kinetic pump and computer temperature control feedback regulating circuit etc.It is characterized in that: when a large amount of hydrops of abdomen (breast) appears in tumor patient, inlet pipeline by device passes through the perfusion kinetic pump with the hydrops sucking-off in the abdomen (breast), and by heat exchanger in the controllable constant-temperature microwave heating storehouse, make the heating of hydrops temperature and remain on 45 ℃, go into abdomen (breast) intracavity by the re-injection of perfusion kinetic pump again, to reach the thermo-chemotherapy of tumor.When a large amount of ascites appears in liver cirrhosis, also can be at interior die mould blood capillary ultrafilter of the exit of this device adjunction, with the waste water that leaches by the sucking-off of vacuum suction pump, and the hepatic ascites after concentrating feeds back the abdominal cavity again, to reach the minimizing PD, the cirrhotic ascites of the ascites that disappears rapidly concentrates the treatment that feeds back.Promptly on uniform machinery, realize cancerous effusion is carried out different treatments with low albumen cirrhotic ascites.
This utility model compared with prior art has following advantage:
1. middle and advanced stage tumor people's intracavity cancerous effusion, available this device carries out thermotherapy, can effectively kill and wound the cancerous cell that plantation is shifted, and the intracavity cancerous effusion alleviates or disappears;
2. the may command tumor further shifts deterioration, and to being suspected to have neoplasm metastasis in the splanchnocoel, the unconspicuous patient of intracavity hydrops can carry out artificial flushing perfusion, warm immersion chemotherapy;
3. but, be suitable for the progressive stage malignant tumor especially and carry out perfusion chemotherapy to invading the intraperitoneal malignant tumor surgical radical treatment person of serous coat or tunicle;
4. can be used for the concentrated feedback of a large amount of ascites of liver cirrhosis, alleviate pressure symptom.
Description of drawings:
Fig. 1 is first kind of example structure sketch map of this utility model
Fig. 2 is second kind of example structure sketch map of this utility model
Fig. 3 is the tumor cell survival rate--the curve chart of heating-up temperature
Among Fig. 1 Fig. 2: 1. outlet conduit, 2. temperature sensor, 3. controllable constant-temperature microwave heating storehouse, 4. heat exchanger, 5. electronic temperature controller, 6. perfusion kinetic pump, 7. medicament reservoir, 8. inlet pipeline, 9. blood capillary ultrafilter, 10. effluent pipeline, 11. vacuum suction pumps, 12. refuse bottles.
Among Fig. 3: I is 42 ℃ of tumor cell survival rate curves, and II is 43 ℃ of tumor cell survival rate curves, and III is 44 ℃ of tumor cell survival rate curves.
The specific embodiment:
First kind of embodiment of a kind of multifunctional heating perfusion unit described in the utility model: as can be seen from Figure 1, it is made up of inlet pipeline 8, perfusion kinetic pump 6, controllable constant-temperature microwave heating storehouse 3, heat exchanger 4 and outlet conduit 1.It is characterized in that: inlet pipeline 8 one terminates at the import of perfusion kinetic pump 6, the outlet of perfusion kinetic pump 6 is connected on the entrance point of the heat exchanger 4 in the controllable constant-temperature microwave heating storehouse 3 by pipeline, the port of export of heat exchanger 4 is connected on the outlet conduit 1, the entrance point of described inlet pipeline 8 is connected to temperature sensor 2, be used for controlling the temperature in controllable constant-temperature microwave heating storehouse 3 by electronic temperature controller 5, described electronic temperature controller 5 is equipped with computer temperature control in addition, real time temperature display screen and superhigh temperature alarm, when the intracavity cancerous effusion appears in tumour patient, in body cavity, insert two conduits, utilize the original hydrops of intracavity or inject normal saline and form artificial hydrops, with water is the heat conduction media, hydrops is pumped in the heat exchanger 4 in the controllable constant-temperature microwave heating storehouse 3 through perfusion kinetic pump 6 by inlet pipeline 8, injects intracavity by conduit outlet again after the heating.Under the monitoring and electronic temperature controller 5 feedback regulations of the temperature sensor 2 of the entrance point of inlet pipeline 8, make and inject the coelomic fluid bulk phase constant heating 40-180 minute that in 43-45 ℃ of scope, continue.In order to increase lethality to cancerous cell, can produce cancerous cell and effectively kill and wound by adding thermal sensitization agent and cancer therapy drug in the medicament reservoir 7 on the inlet pipeline 8, reach serous coat and repair the again assimilation effect of lymphatic vessel oozing out.In whole therapeutic process, do not need discharge chamber water, can not lose albumen, and increase the weight of health depletion, can effectively contain neoplasm metastasis and recurrence like this because of a large amount of extraction intracavity hydrops.
Second kind of embodiment of a kind of multi-functional perfusion unit described in the utility model: as can be seen from Figure 2, it is by inlet pipeline 8, perfusion kinetic pump 6, blood capillary ultrafilter 9 and vacuum suction pump 11 are formed, it is characterized in that: inlet pipeline 8 is connected on the import of perfusion kinetic pump 6, the outlet of perfusion kinetic pump 6 is connected on the import of blood capillary ultrafilter (molecular sieve) 9 by pipeline, outlet conduit 1 is connected on the outlet of blood capillary ultrafilter 9, the Waste outlet of blood capillary ultrafilter 9 is connected on the vacuum suction pump 11 by waste conduit 10, the port of export of vacuum suction pump 11 is connected to refuse bottle 12, when a large amount of ascites appears in patient, can ascites be drawn in the blood capillary ultrafilter 9 by inlet pipeline 8 and perfusion kinetic pump 6, a large amount of ascites are concentrated, and fail back in the splanchnocoel from outlet conduit 1, the refuse that leaches simultaneously is pumped in the refuse bottle 12 by waste conduit 10 and vacuum suction pump 11, can reduce PD like this, eliminate ascites quickly and effectively, alleviate pressure symptom.
Claims (5)
1. a multifunctional heating perfusion unit is made up of inlet pipeline (8), perfusion kinetic pump (6), controllable constant-temperature microwave heating storehouse (3), heat exchanger (4), electronic temperature controller (5) and outlet conduit (1), it is characterized in that: inlet pipeline (8) is connected on the entrance point of perfusion kinetic pump (6), the port of export of perfusion kinetic pump (6) is connected on the entrance point of the heat exchanger (4) in the controllable constant-temperature microwave heating storehouse (3) by pipeline, and outlet conduit (1) is connected on the port of export of heat exchanger (4).
2. a kind of multifunctional heating perfusion unit according to claim 1 is characterized in that: the indirect at inlet pipeline (8) has blood capillary ultrafilter (9).
3. according to claim 1,2 described a kind of multifunctional heating perfusion units, it is characterized in that: the entrance point at inlet pipeline (8) is equipped with temperature sensor (2).
4. according to claim 1,2 described a kind of multifunctional heating perfusion units, it is characterized in that: on the controllable constant-temperature microwave heating storehouse (3) the superhigh temperature alarm is housed.
5. a multifunctional heating perfusion unit is by inlet pipeline (8), perfusion kinetic pump (6), blood capillary ultrafilter (9), vacuum suction pump (11) and refuse bottle (12) are formed, it is characterized in that: inlet pipeline (8) is connected on the entrance point of perfusion kinetic pump (6), the port of export of perfusion kinetic pump (6) is connected on the entrance point of blood capillary ultrafilter (9) by pipeline, outlet conduit (1) is connected on the port of export of blood capillary ultrafilter (9), the Waste outlet of blood capillary ultrafilter (9) is connected on the entrance point of vacuum suction pump (11) by waste conduit (10), and the port of export of vacuum suction pump (11) is connected to a refuse bottle (12).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2009200026699U CN201353311Y (en) | 2009-02-22 | 2009-02-22 | Multifunctional hyperthermic perfusion machine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2009200026699U CN201353311Y (en) | 2009-02-22 | 2009-02-22 | Multifunctional hyperthermic perfusion machine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201353311Y true CN201353311Y (en) | 2009-12-02 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNU2009200026699U Expired - Fee Related CN201353311Y (en) | 2009-02-22 | 2009-02-22 | Multifunctional hyperthermic perfusion machine |
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| CN (1) | CN201353311Y (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105749361A (en) * | 2016-02-01 | 2016-07-13 | 王保朋 | Self-operated drainage device for condensed water in heat-exchange device |
| CN109692369A (en) * | 2019-01-17 | 2019-04-30 | 秦学祥 | The device of self ascites back transfusion treatment uremia ascites is combined in haemodialysis |
-
2009
- 2009-02-22 CN CNU2009200026699U patent/CN201353311Y/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105749361A (en) * | 2016-02-01 | 2016-07-13 | 王保朋 | Self-operated drainage device for condensed water in heat-exchange device |
| CN109692369A (en) * | 2019-01-17 | 2019-04-30 | 秦学祥 | The device of self ascites back transfusion treatment uremia ascites is combined in haemodialysis |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20091202 Termination date: 20140222 |