CN201216760Y - Centrifugal hemocyte washer - Google Patents

Centrifugal hemocyte washer Download PDF

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Publication number
CN201216760Y
CN201216760Y CNU2008201081307U CN200820108130U CN201216760Y CN 201216760 Y CN201216760 Y CN 201216760Y CN U2008201081307 U CNU2008201081307 U CN U2008201081307U CN 200820108130 U CN200820108130 U CN 200820108130U CN 201216760 Y CN201216760 Y CN 201216760Y
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CN
China
Prior art keywords
blood
centrifuge
bag
blood pump
washing machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNU2008201081307U
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Chinese (zh)
Inventor
韩颖
王艳
刘敏霞
王捷熙
权国波
刘安
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Field Blood Transfusion Chinese Academy of Military Medical Sciences
Original Assignee
Institute of Field Blood Transfusion Chinese Academy of Military Medical Sciences
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Priority to CNU2008201081307U priority Critical patent/CN201216760Y/en
Application granted granted Critical
Publication of CN201216760Y publication Critical patent/CN201216760Y/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Abstract

A centrifugal blood cell washing machine comprises a main machine and consumables; a blood pump controlled by a controller and a centrifuge are installed inside the main machine; the controller is electrically connected with a motor of the centrifuge and a motor of the blood pump; the centrifuge is provided with a liquid feeding pipe and a liquid discharging pipe which are connected with one port of the blood pump through a multi-direction joint; the other port of the blood pump leads a plurality of pipelines out of the main machine through a three-forked interface, so that the pipelines are communicated with the consumables respectively; and the consumables include a plurality of cleaning solution bags, waste liquid bags, frozen red blood cell blood bags and finished product bags which are arranged outside the main machine and connected with the three-forked interface of the blood pump through the pipelines. The utility model adopts the controller for automatically controlling the washing process, and adopts the single pump for controlling the processes of washing, discharging waste liquid and transferring finished-product red blood cells, so that the cost is reduced, the procedures are simplified, and the operating methods of the utility model are easy to grasp. Therefore, the utility model has the advantages of small size, lightness, low price, simplified operating procedures and increased washing speed.

Description

Centrifugal hemocyte washing machine
Technical field
This utility model relates to medical equipment, particularly about a kind of novel centrifugal type frozen red cells washing machine.
Background technology
In the treatment of blood transfusion, stored frozen blood is mainly used in rare blood type patient blood transfusion at present.Because viral infection and carrier increase day by day among the blood donor, carry out from body erythrocyte long preservation also being subjected to people's attention gradually.Stored frozen blood also can satisfy the requirement that in emergency circumstances the blood consumption is increased suddenly in addition.Stored frozen blood is that erythrocyte is added glycerol protection liquid, preserves with-80 ℃ of degree, can preserve more than 10 years.When patient needed the infusion erythrocyte, thawed red blood cell was with high saline solution and the washing liquid cyclic washing erythrocyte that oozes, to remove harmful glycerol and free hemoglobin; For the patient that allergic symptom is arranged, also should infusion erythrocyte after the washing, avoid the immunoreation after antibody component in the blood produces blood transfusion.Erythrocyte after the washing can also be removed insalubrious compositions such as hyperlipidemia.
The clinical method of removing glycerol or Washed Red Blood Cells commonly used has two kinds at present: 1) super-magnum centrifuge washing method: the instrument heaviness, be semi-open form, and washing back erythrocyte only can be deposited 24 hours at 4 ℃; 2) U.S.'s 115 types and 215 type hemocyte washing machine methods: 115 type hemocyte washing machine need manual liquid feeding, can not realize automatically, and the design of 215 type washing machine has two peristaltic pumps, realized automatic washing process, but the washing procedure complexity is loaded down with trivial details; And these two kinds of washing machine all need import, cost an arm and a leg, about 350,000 yuans of every price, and the erythrocyte of a unit of washing needs 1 hour.
Summary of the invention
Main purpose of the present utility model provides a kind of miniaturization and has the centrifugal hemocyte washing machine of lower cost, and makes it can reach easy quick and automatic clean result simultaneously.
In order to achieve the above object, this utility model is taked following technical scheme:
A kind of centrifugal hemocyte washing machine comprises main frame and consumptive material, and a blood pump and centrifuge that is controlled by the controller is equipped with in described main frame inside, and described controller is electrically connected with the motor and the blood pump motor of centrifuge; Described centrifuge is established feed tube and drain pipe, is connected with a port of blood pump by Multidirectional connector, and the another port of blood pump is drawn main frame by one three trouble interface with many pipelines and is communicated with described consumptive material respectively.Wherein:
Described blood pump is a peristaltic pump.
Described consumptive material comprises is located at main frame a plurality of washing liquid bags, waste fluid bag, frozen red cells blood bag and finished bag outer and that link to each other by pipeline with three trouble interfaces of blood pump.
Respectively establish an electromagnetic valve of controlling by described controller on each described consumptive material and three pipelines that are communicated with of trouble interfaces.
Other establishes a device that shakes up by described controller control, and described blood bag is placed in this and shakes up on the device.
Other establishes an infusion support that has a hook, described washing liquid bag, finished bag and waste fluid bag is straggly is hung on the hook.
The above centrifugal hemocyte washing machine, the feed tube of described centrifuge stretch into the centrifuge bottom, and drain pipe is located at centrifuge top, establish the feed liquor valve by described controller control on the feed tube, establish the liquid valve by described controller control on the drain pipe.
Between described each washing liquid bag with the parallel connection of branching shape tube for transfusion.
Described frozen red cells blood bag is in parallel with tube for transfusion with finished product blood bag.
Described blood pump rotating speed is 5-300ml/min.
Adopt above design, reduced the volume and weight of washing machine, shortened wash time, simplified operating procedure, and make erythrocyte go the glycerol process to have reduced the contaminated chance of cell carrying out in the closed pipeline relatively, machine cost also reduces greatly.Present technique is compared with 115 type washing machine, adopts controller to control washing process automatically, has realized automatization; Compare with 215 type washing machine, control system is simplified, adopts pump control washing, an effluent discharge and translate into the process of product erythrocyte, the cost reduction, step is easy, is easy to grasp.Therefore make the utlity model has that volume is little, in light weight, price is low, the step that simplifies the operation, the advantage of washing speed accelerated.
Description of drawings
Fig. 1 is a structural representation of the present utility model.
The specific embodiment
Be described in detail structure of the present utility model below in conjunction with accompanying drawing.
This utility model is made of main frame, infusion support and consumptive material three parts, wherein, as shown in Figure 1, be equipped with controller 111, centrifuge 110 and blood pump 108 in the mainframe box 10, controller 111 is electrically connected with the motor of centrifuge 110, can control the startup and the rotating speed of centrifuge 110; Centrifuge 110 is established feed tube that stretches into the centrifuge bottom and the drain pipe that is located at centrifuge top, and feed tube is by 106 controls of feed liquor valve, and drain pipe is by liquid valve 107 controls; Blood pump 108 is a peristaltic pump, port by Multidirectional connector and blood pump 108 of the feed tube of centrifuge 110 and the other end of drain pipe (Fig. 1 represent be left side port) is connected, and the another port of blood pump 108 is branched off interface (using other three lines that are connected with pump to represent among Fig. 1) by one three many pipelines are drawn outside the cabinet 10;
Consumptive material comprises three kinds of washing liquids (1 liquid, 2 liquid, 3 liquid) bag, frozen red cells blood bag, finished bag, waste fluid bag and many pipelines.Three kinds of washing liquid bags are communicated with first fork of blood pump 108 3 trouble interfaces separately by pipeline, pipeline is provided with control valve 101,102 and 103 separately; Frozen red cells blood bag and finished bag are communicated with second fork of blood pump 108 3 trouble interfaces separately by pipeline, pipeline is provided with control valve 104 and 105 separately, and the frozen red cells bag places one to shake up on the device 112; Waste fluid bag is by the junctions of pipeline connection blood pump 108 3 trouble interfaces, and pipeline is provided with control valve 109;
Infusion support is the support (can be 20cm as support length, the diameter of metallic rod can be 1cm) with a plurality of hooks of arranging straggly, and three kinds of washing liquids (1 liquid, 2 liquid, 3 liquid) bag, finished bag, waste fluid bag all can be suspended on this support.Support should be placed on the position near main frame.Be appreciated that infusion support is not an indispensable accessory of the present utility model, also can finish the suspension of above-mentioned various pipe, bag with the simple and easy hook that the scene can conveniently hang.
In the enforcement, controller 111 not only is electrically connected (representing to be electrically connected with dotted arrow among Fig. 1) startup and rotating speed with control centrifuge 110 with the motor of centrifuge 110, controller 111 also is electrically connected (representing to be electrically connected with dotted arrow among Fig. 1) with shaking up device 112, controls its frequency of oscillation and amplitude; Control valve on the pipeline is electromagnetic valve, and controller 111 is connected (among the figure not faithful representation) and controls their keying with these control valves; Controller 111 also is electrically connected (representing to be electrically connected with dotted arrow among Fig. 1) with the motor of blood pump 108, control its wriggling direction and flow velocity.The control circuit of controller can design according to above function introduction in the usual way, also can be with reference to the control circuit of the U.S.'s 215 type hemocyte washing machine.
In concrete enforcement, the apparent size of cabinet 10 can be 40 * 35 * 30 centimetres, and materials such as available engineering plastics or metal are made.
In concrete enforcement, the main effect of blood pump 108 is that cleaning mixture is pumped into the blood bag, fully is mixed into cell suspension with hemocyte, and the drive motors of peristaltic pump can be the CM1-23L20 (model) of cool muscle, and its rotating speed can be set.Because peristaltic pump adopts direct current generator, by regulating the voltage-regulation motor speed of supplying with motor, the peristaltic pump rotating speed is arranged on 5-300 milliliter/min usually, and under this set, washing 200 milliliters of erythrocytic times is 30-50 minute.When adding washing liquid, peristaltic pump wriggling direction from left to right, when the frozen red cells after the dilution enters centrifuge, peristaltic pump wriggling direction from right to left, behind the centrifuge washing, peristaltic pump pumps into waste fluid bag with waste liquid from left to right, and repeated centrifugation washing step repeatedly.After washing finished, peristaltic pump pumped into finished bag with the finished product erythrocyte from left to right.
(referring to Fig. 1) describes the Washed Red Blood Cells process below in conjunction with this utility model structure:
Frozen red cells bag (blood bag) put under 37 ℃ thaw, be placed on then and shake up on the device 112.Open system, controller 111 are opened and are shaken up device 112, frequency of oscillation 3Hz, 1.5 inches of amplitudes.This moment, valve 101 and 104 was opened, and blood pump 108 begins to start flows liquid from left to right, and flow velocity is approximately 25ml/min.Blood pump 108 is computation time by the control flow velocity, and after required amount of liquid all arrived the blood bag, controller 111 controls shook up device 112 time-outs and shake, and leave standstill 2 minutes.Valve-off 101 then, open valve 102, and controller 111 is opened and shaken up device 112, frequency of oscillation 3Hz, 1.5 inches of amplitudes.Blood pump 108 starts once more flows liquid from left to right, and flow velocity is approximately 150ml/min.Left standstill 2 minutes.So far, washing liquid 1 and washing liquid 2 enter the blood bag successively, have reduced the glycerol osmotic pressure.
Valve-off 102 is opened feed liquor valve 106, and blood pump 108 rotates from right to left, and liquid flow in the centrifuge 110 from right to left in the startup blood bag.Controller 111 orders about centrifuge work, and centrifuge is discharged to drain pipe by high speed centrifugation with supernatant, close feed liquor valve 106 this moment, open the control valve 109 on liquid valve 107 and the waste fluid bag pipeline, blood pump 108 rotates from left to right, supernatant is pumped out to waste solution channel flows into waste fluid bag.Valve-off 107 is opened valve 103, opens to shake up device 112, and frequency of oscillation and amplitude are the same, and blood pump 108 start liquid flow from left to right and flow into the blood bag, and flow velocity is approximately 150ml/min.After an amount of washing liquid 3 entered the blood bag, valve-off 103 was opened feed liquor valve 106, and blood pump 108 rotates from right to left, and liquid flow in the centrifuge 110 from right to left in the startup blood bag.Controller 111 orders about centrifuge work, the beginning centrifuge washing.Centrifuge is discharged to drain pipe by high speed centrifugation with supernatant, and close feed liquor valve 106 this moment, opens the control valve 109 on liquid valve 107 and the waste fluid bag pipeline, and blood pump 108 rotates from left to right, supernatant is pumped out to waste solution channel flows into waste fluid bag.Open valve 103 and valve 106, blood pump 108 starts flows liquid from left to right, and flow velocity is approximately 150ml/min, and washing liquid flows into centrifuge 110 in No. 3 washing liquid bags, centrifuge 110 work, beginning centrifuge washing and above-mentioned identical process output to supernatant in the waste fluid bag; Centrifugal repeated washing process like this 3 times.
Open feed liquor valve 106 and control valve 105 at last, control blood pump 108 rotates from left to right, makes the finished product erythrocyte of centrifuge 110 bottoms flow into finished bag.Washing process is finished.
In sum, this utility model adopts accurate peristaltic pump to replace the manual liquid feeding of 115 type blood washing machine, make whole washing process can realize automatization, simultaneously, with peristaltic pump from 215 type blood washing machine two be reduced to one, make washing process easier, step is simple, is convenient to operation; Wherein two external tappings with centrifuge link to each other with peristaltic pump by Multidirectional connector, thus make liquid feeding, effluent discharge and translate into every work such as product erythrocyte can along with peristaltic pump wriggle direction difference and realize.

Claims (10)

1. a centrifugal hemocyte washing machine comprises main frame and consumptive material, it is characterized in that: a blood pump and centrifuge that is controlled by the controller is equipped with in described main frame inside, and described controller is electrically connected with the motor and the blood pump motor of centrifuge; Described centrifuge is established feed tube and drain pipe, is connected with a port of blood pump by Multidirectional connector, and the another port of blood pump is drawn main frame by one three trouble interface with many pipelines and is communicated with described consumptive material respectively.
2, according to the described centrifugal hemocyte washing machine of claim 1, it is characterized in that: described blood pump is a peristaltic pump.
3, according to the described centrifugal hemocyte washing machine of claim 2, it is characterized in that: described consumptive material comprises is located at main frame a plurality of washing liquid bags, waste fluid bag, frozen red cells blood bag and finished bag outer and that link to each other by pipeline with three trouble interfaces of blood pump.
4, according to the described centrifugal hemocyte washing machine of claim 3, it is characterized in that: respectively establish an electromagnetic valve of controlling by described controller on each described consumptive material and three pipelines that are communicated with of trouble interfaces.
5, according to the described centrifugal hemocyte washing machine of claim 3, it is characterized in that: other establishes a device that shakes up by described controller control, and described blood bag is placed in this and shakes up on the device.
6, according to the described centrifugal hemocyte washing machine of claim 3, it is characterized in that: other establishes an infusion support that has a hook, described washing liquid bag, finished bag and waste fluid bag is straggly is hung on the hook.
7, according to the arbitrary described centrifugal hemocyte washing machine of claim 1 to 6, it is characterized in that: the feed tube of described centrifuge stretches into the centrifuge bottom, drain pipe is located at centrifuge top, establish feed liquor valve on the feed tube, establish liquid valve on the drain pipe by described controller control by described controller control.
8, according to the described centrifugal hemocyte washing machine of claim 7, it is characterized in that: between described each washing liquid bag with the parallel connection of branching shape tube for transfusion.
9, according to the described centrifugal hemocyte washing machine of claim 7, it is characterized in that: described frozen red cells blood bag is in parallel with tube for transfusion with finished product blood bag.
10, according to the described centrifugal hemocyte washing machine of claim 7, it is characterized in that: described blood pump rotating speed is 5-300ml/min.
CNU2008201081307U 2008-05-29 2008-05-29 Centrifugal hemocyte washer Expired - Lifetime CN201216760Y (en)

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Application Number Priority Date Filing Date Title
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103060176A (en) * 2013-01-21 2013-04-24 赵阳 Red blood cell treatment instrument
CN104789526A (en) * 2015-05-05 2015-07-22 宋毅 Method and device for preparing frozen and thawed glycerin-removed erythrocytes
CN107929835A (en) * 2017-12-18 2018-04-20 广州市红十字会医院 Hospital blood bank type component rinsing maching

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103060176A (en) * 2013-01-21 2013-04-24 赵阳 Red blood cell treatment instrument
CN104789526A (en) * 2015-05-05 2015-07-22 宋毅 Method and device for preparing frozen and thawed glycerin-removed erythrocytes
CN107929835A (en) * 2017-12-18 2018-04-20 广州市红十字会医院 Hospital blood bank type component rinsing maching

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Granted publication date: 20090408