CN201200431Y - Sampler for living cell - Google Patents
Sampler for living cell Download PDFInfo
- Publication number
- CN201200431Y CN201200431Y CNU2008201091703U CN200820109170U CN201200431Y CN 201200431 Y CN201200431 Y CN 201200431Y CN U2008201091703 U CNU2008201091703 U CN U2008201091703U CN 200820109170 U CN200820109170 U CN 200820109170U CN 201200431 Y CN201200431 Y CN 201200431Y
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- China
- Prior art keywords
- sampler
- wing
- guided way
- flex
- pull bar
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Abstract
The utility model discloses an intravital cell sampler which is composed of a sampler, a slide block and a pull rod. The slide block is sleeved on the pull rod; the splicing end of the pull rod is inserted into a cross trough of the sampler; the sampler is an integral machining molding piece; the sampler is provided with a flexible wing A, a flexible wing B and a tapered strut; one end of the tapered strut is a supporting end, and the other end of the tapered strut is a propping end; the end surface of the propping end is a circular surface, and the end surface of the supporting end is a plane; and a convex ball is arranged on an outer board face of the flexible wing A, and a convex ball B is arranged on the outer face of the flexible wing B. The sampler of the intravital cell sampler of the utility model adopts a flexible structural design which accords with the physiological requirement of a human body, and is easy to collect intravital cell tissues at focus parts; the combination of a sampling head with a flexible structure and a sampling head with a small size can decrease the sizes of a bottle mouth and a bottle body of a biological kit so as to reduce the use of biological reagent and enlarge the serviceable range of the intravital cell sampler.
Description
Technical field
This utility model relates to a kind of medical apparatus and instruments, more particularly says, be meant a kind of have shrink with spreading performance, can be with the isolating living cell sampler of sampler.
Background technology
Hospital is when carrying out the active somatic cell sampling to lesions position, the scraper plate that mostly adopts bamboo or timber to make at present carries out the active somatic cell sampling.This scrapes that plate bulk is big, shape and material do not meet the Human Physiology requirement, and patient uses uncomfortable.In addition, the cell concentration of obtaining is few, because of the biotinylation kit volume of the big use of volume also along with becoming big, make that the reagent solution of usefulness is more, cause reagent solution waste or cost to increase.Because reagent solution is more, also longer to the cell culture time of gathering, reduced detection efficiency.
Summary of the invention
The purpose of this utility model provides a kind of Human Physiology requirement that meets, use the living cell sampler of a kind of minute body structure that biological reagent liquid is few, the test kit volume is little, the sampling head of this living cell sampler is designed to flexible structure, and at the centre of two flex-wings design one tapered strut, it can be played a supporting role, can strengthen the area of sampling, obtain more active somatic cell tissue.Tapered strut adopts the segmental structure design, meets the Human Physiology requirement more.
Living cell sampler of the present utility model is made of sampler (1), slide block (2) and pull bar (3), and slide block (2) is socketed on the pull bar (3), in the cross recess (16a) of inserted terminal (36) dip sampler (1) of pull bar (3).
Sampler (1) is an one machine-shaping part, and sampler (1) is provided with A flex-wing (11), B flex-wing (12), tapered strut (13); One end of tapered strut (13) is fastener (15), and the other end of tapered strut (13) is top (14), and the end face of top (14) is a circular face, and the end face of fastener (15) is the plane; The outer plate surface of A flex-wing (11) is provided with A dome ball (101), and the outer plate surface of B flex-wing (12) is provided with B dome ball (102), and A flex-wing (11) is symmetrical arranged with the centrage of B flex-wing (12) with tapered strut (13); Tapered strut (13) is provided with cuts apart cross section (107), cut apart cross section (107) to fastener (15) for taper shell of column (105), be evenly equipped with the dome ball on the upper face (108) of taper shell of column (105), what cut apart cross section (107) to top (14) is tapered cylinder section (106), is evenly equipped with the dome ball on the tapered cylinder section (106); The center of jacking block (16) has cross recess (16a), and the inserted terminal (36) that cross recess (16a) is used for pull bar (3) inserts, thereby realizes the flexible connection of sampler (1) and pull bar (3); A guided way (31), B guided way (32), C guided way (33), D guided way (34) are arranged on the pull bar (3), A guided way (31) is relative with C guided way (33), B guided way (32) is relative with D guided way (34), A guided way (31) is fastened in the B conduit (223) of slide block (2), and C guided way (33) is fastened in the A conduit (213) of slide block (2); Pull bar (3) is a cross structure, and an end of pull bar (3) is inserted terminal (36), and the other end of pull bar (3) is cylinder handle (35), and cylinder handle (35) is a column structure, and is provided with a plurality of circular protrusions (35a) that are used to increase frictional force on periphery; Pull bar (3) is provided with A guided way (31), B guided way (32), C guided way (33), D guided way (34); A guided way (31) is oppositely arranged on the same horizontal line with C guided way (33), and B guided way (32) is oppositely arranged on the same horizontal line with D guided way (34); A guided way (31) is fastened in A conduit (123) and the B conduit (223) with C guided way (33).
Slide block (2) is a concave structure, and the center of slide block (2) has the cavity (23) that is used to place pull bar (2), and the both sides of cavity (23) are provided with A side arm (21), B side arm (22); The inboard of A side arm (21) is provided with A semicolumn (211), B semicolumn (212), between A semicolumn (211) and the B semicolumn (212) A conduit (213) is arranged; The C guided way (23) that A conduit (213) is used for pull bar (2) slides betwixt; The inboard of B side arm (22) is provided with C semicolumn (221), D semicolumn (222), between C semicolumn (221), the D semicolumn (222) B conduit (223) is arranged; The D guided way (24) that B conduit (223) is used for pull bar (2) slides betwixt.
Described living cell sampler, an end of an end of A flex-wing (11) and B flex-wing (12) is intersected in jacking block (16) and locates, and the other end of A flex-wing (11) is bonded on the A plate face (103) of tapered strut (13), and is positioned at tapered strut (13) length
The place; The other end of B flex-wing (12) is bonded on the B plate face (104) of tapered strut (13), and is positioned at tapered strut (13) length
The place.
Described living cell sampler, position, the dome bulb viscose fibre fine hair of sampler (1), described fibre fluff adopts 666 grades of materials of nylon, and fibre fluff length is 1.0～2.0mm.
Described living cell sampler adopts the nonpoisonous polypropylene material.
This utility model divides the advantage of the living cell sampler of body structure to be: the flexible structure design of (1) sampling head, meet the Human Physiology requirement, and be easy to collect the active somatic cell tissue of lesions position.(2) the dome ball that designs on the sampling head helps the collection of cell, perhaps at the position, dome bulb of sampling head viscose fibre fine hair, more helps the cell tissue collection at wound and rotten to the corn position.(3) adopt flexible material to make, interstice is big, causes artificial damage when being difficult for lesions position taken a sample.(4) structure of two flex-wings of employing and a tapered strut make the contact area of sampling head and lesions position strengthen, thereby the active somatic cell tissue mass that obtains is many, and the abnormal cell in the diagnosis is difficult for by omission.(5) combination of the sampling head of flexible structure and undersized sampling head has been expanded the scope of application of living cell sampler, as cervix uteri, oral cavity, nose, ear etc.(6) living cell sampler also can carry out direct sample to lesions position in the operation of opening.
Description of drawings
Fig. 1 is the structure chart of this utility model living cell sampler.
Fig. 2 is the structure chart of this utility model slide block.
Fig. 2 A is the structure chart at another visual angle of this utility model slide block.
Fig. 3 is the structure chart of this utility model sampler.
Fig. 4 is the structure chart of this utility model pull bar.
Fig. 4 A is the A-A view of this utility model pull bar.
Structure chart when Fig. 5 is the work of this utility model living cell sampler.
Fig. 6 is the structure chart of this utility model living cell sampler when collapsing into biotinylation kit.
Among the figure: 1. sampler 11.A flex-wing 12.B flex-wing 13. tapered struts
14. come directly towards 15. fasteners, 16. jacking block 16a. cross recess 101.A dome balls
102.B dome ball 103.A plate face 104.B plate face 105. taper shell of columns 106. tapered cylinder sections
107. cut apart cross section 108. upper faces, 2. slide block 21.A side arm 211.A semicolumns
212.B semicolumn 213.A conduit 22.B side arm 221.C semicolumn 222.D semicolumn
223.B conduit 23. cavitys 3. pull bar 31.A guided way 32.B guided ways
33.C guided way 34.D guided way 35. cylinder handle 35a. circular protrusions 36. inserted terminals
37. locating surface
The specific embodiment
Below in conjunction with accompanying drawing this utility model is described in further detail.
This utility model be a kind of have shrink with spreading performance, the isolating living cell sampler of sampler can be made of sampler 1, slide block 2 and pull bar 3, slide block 2 is socketed on the pull bar 3, in the cross recess 16a of inserted terminal 36 dip sampler 1 of pull bar 3.
Referring to Fig. 1, shown in Figure 3, sampler 1 is an one machine-shaping part, selects the nonpoisonous polypropylene material for use; Sampler 1 is provided with A flex-wing 11, B flex-wing 12, tapered strut 13; One end of tapered strut 13 is a fastener 15, and the other end of tapered strut 13 is top 14, and the end face of top 14 is a circular face, and the end face of fastener 15 is the plane; When fastener 15 contacts with the medial surface of jacking block 16, the size (referring to shown in Figure 5) when just this utility model living cell sampler enters lesions position and takes a sample.The outer plate surface of A flex-wing 11 is provided with A dome ball 101, and the outer plate surface of B flex-wing 12 is provided with B dome ball 102, and A flex-wing 11 is symmetrical arranged with the centrage of B flex-wing 12 with tapered strut 13; One end of A flex-wing 11 and an end of B flex-wing 12 are intersected in jacking block 16 places, and the center of jacking block 16 has cross recess 16a, and the inserted terminal 36 that cross recess 16a is used for pull bar 3 inserts, thereby realize the flexible connection of sampler 1 and pull bar 3; The other end of A flex-wing 11 is bonded on the A plate face 103 of tapered strut 13, and is positioned at tapered strut 13 length
The place; The other end of B flex-wing 12 is bonded on the B plate face 104 of tapered strut 13, and is positioned at tapered strut 13 length
The place.In this utility model, tapered strut 13 length
The cross section at place is called cuts apart cross section 107, this is cut apart cross section 107 to this section of fastener 15 and is called taper shell of column 105, be evenly equipped with the dome ball on the upper face 108 of taper shell of column 105, the lower face, this section of cutting apart cross section 107 to top 14 is called tapered cylinder section 106 structures, is evenly equipped with the dome ball on the tapered cylinder section 106.The dome ball is used to obtain the active somatic cell of (gluing) lesions position.
In this utility model, shown in Fig. 4, Fig. 4 A, A guided way 31, B guided way 32, C guided way 33, D guided way 34 are arranged on the pull bar 3, A guided way 31 is relative with C guided way 33, B guided way 32 is relative with D guided way 34, A guided way 31 is fastened in the B conduit 33 of slide block 2, and C guided way 33 is fastened on the A conduit 33 interior (shown in Fig. 2, Fig. 2 A) of slide block 2.Living cell sampler of the present utility model promotes slide block 2 by the operator and slides to inserted terminal 36 on pull bar 3, can make sampler 1 be shrunk to as shown in Figure 6 state, simultaneously sampler 1 is pushed in the biotinylation kit, promptly sampler 1 comes off from the inserted terminal 36 of pull bar 3.The A flex-wing 11 of sampler 1, B flex-wing 12 help placing the bottle of biotinylation kit with being bonded at active somatic cell on the dome ball (the B dome ball 102 on the A dome ball 101 on the lateral surface of A flex-wing 11, the lateral surface of B flex-wing 12) shrinking under the extruding of slide block 2, can reduce use, improve incubation time biological reagent.Consider from another point of view, can reduce the design of the bottleneck of overall dimensions (bottleneck, bottle) to biotinylation kit and biotinylation kit, make on the reagent rack and can place more biotinylation kit, improve the efficient that active somatic cell is detected.
Dome ball on the sampler 1 of this utility model design also can more help the cell tissue collection at wound and rotten to the corn position at position, dome bulb viscose fibre fine hair.Described fibre fluff adopts 666 grades of materials of nylon, and fibre fluff length is 1.0～2.0mm.
The total length of tapered strut 13
The cross section at place is called cuts apart cross section 107, cut apart cross section 107 to this section of fastener 15 and be called taper shell of column 105, be evenly equipped with the dome ball on the upper face 108 of taper shell of column 105, the lower face, this section of cutting apart cross section 107 to top 14 is called tapered cylinder section 106, is evenly equipped with the dome ball around the tapered cylinder section 106.
Referring to shown in Figure 4, pull bar 3 is a cross structure, and an end of pull bar 3 is inserted terminal 36 (inserted terminal 36 is arranged on the locating surface 37), and the other end of pull bar 3 is a cylinder handle 35, cylinder handle 35 is a column structure, and is provided with a plurality of circular protrusions 35a that are used to increase frictional force on periphery.Described locating surface 37 contacts with jacking block 16, and inserts and pluck in the end 36 insertion cross recess 16a, and sampler 1 can change locating surface 37 shape of sampler 1 as supporting surface when sampling.Pull bar 3 is provided with A guided way 31, B guided way 32, C guided way 33, D guided way 34; Usually, A guided way 31 is oppositely arranged on the same horizontal line with C guided way 33, and B guided way 32 is oppositely arranged on the same horizontal line with D guided way 34.In utility model, A guided way 31 is fastened in A conduit 123 and the B conduit 223 with C guided way 33, by user pushing drawing rod 3, make slide block 2 on pull bar 3, slide, when slide block 2 slides into pull bar 3 with sampler 1 one ends, sampler 1 can be shunk, thereby make sampler of the present utility model put into the less Biosample box of bottleneck, thereby reach the use that reduces test fluid, make the testing time shorten, reduced the time of pair cell tissue culture.
Shown in Fig. 1, Fig. 2, Fig. 2 A, slide block 2 is a concave structure, and the center of slide block 2 has the cavity 23 that is used to place pull bar 2, and the both sides of cavity 23 are provided with A side arm 21, B side arm 22;
The inboard of A side arm 21 is provided with A semicolumn 211, B semicolumn 212, between A semicolumn 211 and the B semicolumn 212 A conduit 213 is arranged; The C guided way 23 that A conduit 213 is used for pull bar 2 slides betwixt.The width of A conduit 213 is consistent with the thickness of C guided way 123.
The inboard of B side arm 22 is provided with C semicolumn 221, D semicolumn 222, between C semicolumn 221, the D semicolumn 222 B conduit 223 is arranged; The D guided way 24 that B conduit 223 is used for pull bar 2 slides betwixt.The width of B conduit 223 is consistent with the thickness of A guided way 121.
In this utility model, A semicolumn 211, B semicolumn 212 are oppositely arranged on the inboard of A side arm 21, B side arm 22 with C semicolumn 221, D semicolumn 222.The guided way that the structural design of semicolumn helps on the pull bar 2 slips in the conduit.
The flexible structure design of the sampling head of this utility model living cell sampler meets the Human Physiology requirement, is easy to collect the active somatic cell tissue of lesions position.In addition, the sampling head of flexible structure and the combination of undersized sampling head have been expanded the scope of application of living cell sampler, as cervix uteri, oral cavity, nose, ear etc.Undersized sampling head structural design has reduced the volume of biotinylation kit, has also reduced the use of reagent solution simultaneously, has reduced the detection cost, has improved detection efficiency.The minimizing of reagent solution also makes the time of cultivating active somatic cell shorten.
This utility model living cell sampler adopts the nonpoisonous polypropylene material, and interstice is big, causes artificial damage when being difficult for lesions position taken a sample.Because adopt the nontoxic materials processing of odorless, this sampler structure is regular and high temperature resistant, is easy to sterilize under hot conditions; Because of the material of choosing is light, whole sampler is easy to medical worker's operation again.
This utility model living cell sampler adopts the structure of two flex-wings and a tapered strut, make the contact area of sampling head and lesions position strengthen, thereby the active somatic cell tissue mass that obtains is many, and the abnormal cell in the diagnosis is difficult for by omission.
Claims (4)
1, a kind of living cell sampler is characterized in that: by sampler (1), slide block (2) and and pull bar (3) constitute, slide block (2) is socketed on the pull bar (3), in the cross recess (16a) of inserted terminal (36) dip sampler (1) of pull bar (3);
Sampler (1) is an one machine-shaping part, and sampler (1) is provided with A flex-wing (11), B flex-wing (12), tapered strut (13); One end of tapered strut (13) is fastener (15), and the other end of tapered strut (13) is top (14), and the end face of top (14) is a circular face, and the end face of fastener (15) is the plane; The outer plate surface of A flex-wing (11) is provided with A dome ball (101), and the outer plate surface of B flex-wing (12) is provided with B dome ball (102), and A flex-wing (11) is symmetrical arranged with the centrage of B flex-wing (12) with tapered strut (13); One end of one end of A flex-wing (11) and B flex-wing (12) is intersected in jacking block (16) and locates, the center of jacking block (16) has cross recess (16a), the inserted terminal (36) that cross recess (16a) is used for pull bar (3) inserts, thereby realizes the flexible connection of sampler (1) and pull bar (3); Tapered strut (13) is provided with cuts apart cross section (107), cut apart cross section (107) to fastener (15) for taper shell of column (105), be evenly equipped with the dome ball on the upper face (108) of taper shell of column (105), what cut apart cross section (107) to top (14) is tapered cylinder section (106), is evenly equipped with the dome ball on the tapered cylinder section (106);
Pull bar (3) is a cross structure, and an end of pull bar (3) is inserted terminal (36), and the other end of pull bar (3) is cylinder handle (35), and cylinder handle (35) is a column structure, and is provided with a plurality of circular protrusions (35a) that are used to increase frictional force on periphery; Pull bar (3) is provided with A guided way (31), B guided way (32), C guided way (33), D guided way (34); A guided way (31) is oppositely arranged on the same horizontal line with C guided way (33), and B guided way (32) is oppositely arranged on the same horizontal line with D guided way (34); A guided way (31) is fastened in A conduit (123) and the B conduit (223) with C guided way (33);
Slide block (2) is a concave structure, and the center of slide block (2) has the cavity (23) that is used to place pull bar (2), and the both sides of cavity (23) are provided with A side arm (21), B side arm (22); The inboard of A side arm (21) is provided with A semicolumn (211), B semicolumn (212), between A semicolumn (211) and the B semicolumn (212) A conduit (213) is arranged; The C guided way (23) that A conduit (213) is used for pull bar (2) slides betwixt; The inboard of B side arm (22) is provided with C semicolumn (221), D semicolumn (222), between C semicolumn (221), the D semicolumn (222) B conduit (223) is arranged; The D guided way (24) that B conduit (223) is used for pull bar (2) slides betwixt.
2, the living cell sampler of integrative-structure according to claim 1, it is characterized in that: an end of an end of A flex-wing (11) and B flex-wing (12) jacking block (16) that crosses is located, the other end of A flex-wing (11) is bonded on the A plate face (103) of tapered strut (13), and is positioned at tapered strut (13) length
The place; The other end of B flex-wing (12) is bonded on the B plate face (104) of tapered strut (13), and is positioned at tapered strut (13) length
The place.
3, the living cell sampler of integrative-structure according to claim 1 is characterized in that: position, the dome bulb viscose fibre fine hair of sampling head (11), and described fibre fluff adopts 666 grades of materials of nylon, and fibre fluff length is 1.0～2.0mm.
4, the living cell sampler of integrative-structure according to claim 1 is characterized in that: living cell sampler adopts the nonpoisonous polypropylene material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2008201091703U CN201200431Y (en) | 2008-07-11 | 2008-07-11 | Sampler for living cell |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2008201091703U CN201200431Y (en) | 2008-07-11 | 2008-07-11 | Sampler for living cell |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201200431Y true CN201200431Y (en) | 2009-03-04 |
Family
ID=40422743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNU2008201091703U Expired - Fee Related CN201200431Y (en) | 2008-07-11 | 2008-07-11 | Sampler for living cell |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201200431Y (en) |
-
2008
- 2008-07-11 CN CNU2008201091703U patent/CN201200431Y/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: PANG YAHONG Owner name: WU YUHONG Free format text: FORMER OWNER: YAKEKANGDA TECH INST., BEIJING Effective date: 20110104 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 100073 NO.13-107, HUAYUAN XINDI, TAIPINGQIAO, FENGTAI DISTRICT, BEIJING TO:100073 NO.13-2101, HUAYUANXIN, TAIPINGQIAO, FENGTAI DISTRICT, BEIJING |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20110104 Address after: 100073 Beijing city Fengtai District Taipingqiao Huayuan new No. 13-2101 Co-patentee after: Pang Yahong Patentee after: Wu Yuhong Address before: 100073 Beijing city Fengtai District Taipingqiao Huayuan new No. 13-107 Patentee before: Yakekangda Tech Inst., Beijing |
|
| DD01 | Delivery of document by public notice |
Addressee: Pang Yahong Document name: Notification to Pay the Fees |
|
| DD01 | Delivery of document by public notice |
Addressee: Wu Yuhong Document name: Notification of Termination of Patent Right |
|
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20090304 Termination date: 20120711 |