CN201192337Y - Ring platform for measuring study memory capacity of mouse - Google Patents
Ring platform for measuring study memory capacity of mouse Download PDFInfo
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- CN201192337Y CN201192337Y CNU2008200348058U CN200820034805U CN201192337Y CN 201192337 Y CN201192337 Y CN 201192337Y CN U2008200348058 U CNU2008200348058 U CN U2008200348058U CN 200820034805 U CN200820034805 U CN 200820034805U CN 201192337 Y CN201192337 Y CN 201192337Y
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Abstract
The utility model relates to an annular platform used for testing the learning and memory ability of a mouse, which comprises a circular platform (2) arranged on a bracket (1). A plurality of open pores (4) are evenly formed on the peripheral inner side of the platform; an electrical stimulus grid (5) is embedded on the middle surface of the platform; an escape tunnel (7) installed on an orbit (6) is arranged under the open pores (4); a movable probe (8) used for probing the entering-in of an animal is also arranged at the center of the platform surface; the escape tunnel (7) is a movable part which can be drawn out; all connecting wires in each circuit are connected to an acquisition control system (3). The annular platform is used for testing the learning and memory ability of the mouse, solves the automatic detection recording problem of the annular platform, and also provides the electrical stimulus function.
Description
Technical field
This utility model is a kind of behavioristics's instrument that learning and memory abilities in aging mice is tested, and relates to a kind of ring-shaped platform device that electricity irritation and infrared detection function can be provided mice, is used for the research of Medical Biology and pharmaceutical field.
Background technology
Mice has the characteristic of detesting high light.Under bright light environments, mice will seek the dark place and hide.And to correctly find hide, must utilize the clue in the environment to carry out space orientation.The ability of accepting the mice space learning memory of different disposal such as medicine or old and feeble effect can change.
(circular platform CP) was used for the detection of rat space learning memory ability by Barnes, so claim the Barnes labyrinth again to ring-shaped platform first in 1979.The research that it is used for mice space learning memory ability is still few.
The ring-shaped platform device has nothing in common with each other on parameters such as platform diameter and number of aperture, is the white round platform of diameter 122cm as the device of Bach group, and periphery has the hole of 40 equally distributed diameter 5cm, and the tunnel of runing away under the hole wherein can be used for mice and hides.Enclose the high black wall with 15cm but the device of Pompl group is the white round platform of diameter 69cm, the peripheral equally distributed of platform is 16 apertures that diameter is 4.5cm.
Traditional ring-shaped platform program adopts manual record.The index of record only is wrong number and incubation period.The mistake number is meant the number of times in search non-tunnel hole.Be that mice is found the time of being consumed before the correct platform duct incubation period.
The efficient of manual record is low, index is few, data precision is low.The research technique of this moment is single, as research technique that electricity irritation can not be provided, can not measure associating inquiry learning memory ability, can not accurately estimate the active degree of mice, and can not document image etc.When carrying out the research of old Mus ability of learning and memory, because the fear of Aged Mice and anxiety level increase, female Mus often causes test period long if lack the means of electricity irritation.Therefore, develop a kind of practically, the accuracy of detection height can detect the ability of learning and memory of multiple character and provide automatization's ring-shaped platform of more research technique and data that important and practical meanings and using value are arranged.
Summary of the invention
For solving the problem that existing ring-shaped platform exists, this utility model provides a kind of ring-shaped platform that learning and memory abilities in aging mice is tested of being used for, this ring-shaped platform has solved the automatic detection record problem of platform, and electricity irritation and infrared detection function can be provided.
The technical solution of the utility model is as follows:
A kind of ring-shaped platform that learning and memory abilities in aging mice is tested of being used for, comprise platform (2) composition that is positioned on the support (1), the periphery that it is characterized in that this platform (2) has a plurality of perforates (4), electricity irritation grid (5) are embedded in platform surface, be provided with the tunnel of runing away (7) in one or more perforates (4) below, on platform, also be provided with the movable probe (8) that is used for detecting animal and enters.
Be provided with the detection components of tool emission and the parallel infrared light of the multichannel of receiving function (14) at the medial surface of perforate (4).
Electricity irritation grid (5) are embedded in platform surface at interval by a plurality of copper sides lines (10) and constitute, and are provided with binding post (9) on copper side's line (10).
Movable probe (8) is located at the central authorities at platform surface.
Mounting means at the tunnel of runing away (7) at platform (2) back side is: platform (2) back side perforate (4) below is equipped with track (6), and track (6) is provided with the tunnel of runing away (7).
Electricity irritation grid, animal activity are popped one's head in and integration is installed on the infrared detection assembly of each perforate, the infrared circuit of the tunnel of runing away all inserts signal acquisition controller.The tunnel of runing away is the movable part that can extract, and is installed on the below in certain several hole of platform.Be provided with in the central authorities of platform surface and be used for the movable probe that detecting animal enters.
The utility model has the advantages that:
1, this utility model is simple in structure, and cost is low.Adopt modular organization, be easy to safeguard the reliability height.Has good engineering practicability.
2, electricity irritation of the present utility model and data acquisition are controlled by acquisition control system, the precision height, and data acquiring frequency can reach 50 times/second.
3, this utility model can improve test efficiency to the beginning and the end identification automatically of test.
4, realized this important research technique of electricity irritation on ring-shaped platform, the electricity irritation grid match with interlock circuit, can realize the complicated electric pulse stimulation that requires.
Description of drawings
Fig. 1 is a structural representation of the present utility model.
Fig. 2 is the frame for movement sketch map at platform 2 back sides.
Fig. 3 is the frame for movement sketch map (showing the part) in platform 2 fronts.
Fig. 4 is the frame for movement sketch map of a perforate 4, and wherein, Fig. 4 a is the front view at perforate 4 places, and Fig. 4 b is that B-B of Fig. 4 a is to cutaway view.
Have among the above figure: support 1, platform 2, signal acquisition controller 3, perforate 4, electricity irritation grid 5, track 6, the tunnel 7 of runing away, movable probe 8; Binding post 9, copper side's line 10, binding post are installed through hole 11, groove 12, groove 13, parallel infrared light 14.
The specific embodiment
Consult Fig. 1, Fig. 2, Fig. 3, Fig. 4, ring-shaped platform in the present embodiment is made up of a circular platform 2 that is positioned on the support 1, the peripheral inboard of this platform evenly has a plurality of perforates 4, electricity irritation grid 5 are embedded in the intermediary surface of platform, below perforate 4, be provided with the tunnel 7 of runing away that is installed on the track 6, also be provided with in the central authorities of platform surface and be used for the movable probe 8 that detecting animal enters.The tunnel 7 of runing away is the movable parts that can extract, and the wiring of each several part circuit all inserts acquisition control system 3.Groove 12,13 is arranged, structure such as Fig. 4 b in the perforate 4.
The method that electricity irritation grid 5 usefulness of ring-shaped platform are following realizes: platform material requires insulation, waterproof, as epoxy resin board, digs the square groove that 3mm is wide, 3mm is dark at platform surface, embeds copper side's line 10 of 3mm * 3mm, and surface finish is smooth.Copper side's line needs welding in advance to go up binding post 9, and lead-out wire is positioned at the platform below.The width of groove and copper cash can be selected between 2-5mm, after animal contacts, can provide effective electricity irritation to get final product.
The infrared light detection assembly that is installed on each circular hole generates the parallel infrared light of multichannel different frequency, can avoid the dead angle of infrared acquisition, simultaneously can the phase mutual interference.The way of infrared light can reference bore size select general 2-4 the tunnel.
Binding post is installed through hole 11 totally two rows, and the binding post 9 of electricity irritation grid constitutes positive and negative electrode respectively by drawing in the through hole.Movable probe 8 places are equipped with the infrared light emission and receive to managing 3 pairs, as the automatic signal source of on-test.The tunnel 7 of runing away that present embodiment provides can be provided with 4 or more at most, is installed on the below in certain several hole of platform.
Claims (5)
1. one kind is used for ring-shaped platform that learning and memory abilities in aging mice is tested, comprise the platform (2) that is positioned on the support (1), the periphery that it is characterized in that this platform (2) has a plurality of perforates (4), electricity irritation grid (5) are embedded in platform surface, be provided with the tunnel of runing away (7) in one or more perforates (4) below, on platform, also be provided with the movable probe (8) that is used for detecting animal and enters.
2. the ring-shaped platform that learning and memory abilities in aging mice is tested of being used for according to claim 1 is characterized in that: the detection components that is provided with tool emission and the parallel infrared light of the multichannel of receiving function (14) at the medial surface of perforate (4).
3. the ring-shaped platform that learning and memory abilities in aging mice is tested of being used for according to claim 1 is characterized in that electricity irritation grid (5) are embedded in platform surface at interval by a plurality of copper sides lines (10) and constitute, and is provided with binding post (9) on copper side's line (10).
4. the ring-shaped platform that learning and memory abilities in aging mice is tested of being used for according to claim 1 is characterized in that movable probe (8) is located at the central authorities at platform surface.
5. the ring-shaped platform that learning and memory abilities in aging mice is tested of being used for according to claim 1, it is characterized in that at the mounting means of the tunnel of runing away (7) at platform (2) back side being: platform (2) back side perforate (4) below is equipped with track (6), and track (6) is provided with the tunnel of runing away (7).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2008200348058U CN201192337Y (en) | 2008-04-23 | 2008-04-23 | Ring platform for measuring study memory capacity of mouse |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2008200348058U CN201192337Y (en) | 2008-04-23 | 2008-04-23 | Ring platform for measuring study memory capacity of mouse |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201192337Y true CN201192337Y (en) | 2009-02-11 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNU2008200348058U Expired - Fee Related CN201192337Y (en) | 2008-04-23 | 2008-04-23 | Ring platform for measuring study memory capacity of mouse |
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| Country | Link |
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| CN (1) | CN201192337Y (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114847229A (en) * | 2022-06-02 | 2022-08-05 | 山西医科大学第一医院 | Behavioural method for evaluating learning and memory of mouse based on treadmill |
-
2008
- 2008-04-23 CN CNU2008200348058U patent/CN201192337Y/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114847229A (en) * | 2022-06-02 | 2022-08-05 | 山西医科大学第一医院 | Behavioural method for evaluating learning and memory of mouse based on treadmill |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20090211 Termination date: 20100423 |