CN201153990Y - Novel electric control multifunctional spinal cord beating device - Google Patents
Novel electric control multifunctional spinal cord beating device Download PDFInfo
- Publication number
- CN201153990Y CN201153990Y CNU2007200607700U CN200720060770U CN201153990Y CN 201153990 Y CN201153990 Y CN 201153990Y CN U2007200607700 U CNU2007200607700 U CN U2007200607700U CN 200720060770 U CN200720060770 U CN 200720060770U CN 201153990 Y CN201153990 Y CN 201153990Y
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- spinal cord
- hitting
- novel electric
- bump
- animal
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Abstract
The utility model relates to a novel electric control animal spinal cord hitting ware for producing a spinal cord injury animal model, which comprises a spinal cord hitting system (1), an electric control system (2) and an animal spine processus spinosus fixing device (3), wherein, the spinal cord hitting system is provided with an elasticity regulating protector and a return-to-zero electronic altitude scale (18), as well as a liquid crystal prompting screen (19). A hitting bar and a pilot sleeve thereof are provided with the replaceable equipment with different diameters and weights. The electric control system comprises an electromagnet control circuit and an impacting contact cue circuit, wherein, the electromagnet is made into an electromagnetism ceiling pan (11) arranged right above the pilot sleeve. The hitting ware of the utility model is provided with the reliable animal spine processus spinosus fixing device with different sizes, so as to be applied to experimental animals of different species. The electric control hitting bar has accurate hitting, stabilization and efficacy, and an electron scale can accurately control the hitting height and the impacting contact cue circuit, so as to produce standardized animal spinal cord injury models with variable degrees of injuries, and the accident prevention hitting device can prevent an unexpected hitting.
Description
Affiliated technical field
This utility model relates to the device that a kind of new electronic control that is used to make animal model with spinal cord damnification hits animal spinal cord, especially can be common to the novel electric-controlled multi-use spinal cord beating device of big or small laboratory animals such as Rodents and primates.
Background technology
Spinal cord injury (spinal card injury), SCI is the very high disease of a kind of disability rate, and the treatment of spinal cord injury is failed to make a breakthrough so far.The effect of the spinal cord injury model of reliability height, good reproducibility intervention means for the pathophysiological mechanism of illustrating spinal cord injury with after estimating damage is very crucial.Used the weight Weight-Dropping that falls the earliest in 1911 from Allen, since the WD method, many scholars study and improve the animal model of setting up contusion of spinal cord, but these improved devices are very expensive mostly and market-oriented degree is low, domestic seldom research unit is equipped with this class device, moreover because restraining factors such as laboratory animal source and funds, these percussion devices also only can be made the Rodents small animal model.Owing to can't rely on the clinical pathological research of carrying out system, to carry out the meaning of spinal cord injury experimentation self-evident by setting up primate model.The Chinese patent communique had once been announced the Chinese utility model patent of " spinal cord injury animal experiment device capable " by name on July 6th, 2005, Granted publication CN2708425Y, it comprises pedestal, be located at the support member on the pedestal, transverse link with support member flexibly connects is fixedly connected on orienting locator and interior dropping hammer thereof on the transverse link.By the support member in the such scheme, the transverse link that rotates on support member is at the upper and lower mobile orienting locator of the anchor clamps of transverse link.This device has its weak point: 1, no animal spinous process fixture, easily cause to hit and forbidden; 2, there is not anti-error percussion device, the strike that easily meets accident; 3, do not have the suggestion device of strike, when requiring to cause little damage, can't determine whether to hit spinal cord; 4, Artificial Control is decontroled the bump rod, and degree of accuracy is poor; 5, artificial decision bump is highly inaccurate.So this scheme strike effect is effectively stable inadequately, its narrow application range can not be common to Rodents and primate laboratory animal in addition.
The utility model content
The purpose of this utility model, it is accurate, effectively stable just to provide a kind of strike, not only can produce damage, standardized animal spinal cord damage model in various degree, and can be applicable to the novel electric-controlled multi-use spinal cord beating device of different genera laboratory animal.
For realizing above-mentioned utility model purpose, novel electric-controlled multi-use spinal cord beating device of the present utility model, comprise the spinal cord beating system, it is characterized in that: also include electric-control system, described spinal cord beating system is by base, column, elevating bracket and bump bar construction, the elevating bracket that the height dog screw is installed can slide up and down to be supported on the column that is fixed on base, the cantilever end that crosses out on the elevating bracket is fixed with the excellent metal pilot sleeve of vertical bump, and the metal bump rod of top band bulge loop can slide up and down to be through in the pilot sleeve; Described electric-control system is electric magnet and control circuit thereof, electric magnet make electromagnetism inhale take over a business to be installed in pilot sleeve directly over, control circuit for electromagnet is by ac power supply.
Described column is two parallel columns, and the top has crossbeam to connect.
On the basis of the above, this utility model also can be further perfect:
Include animal spinous process fixture, it is made up of at least one group two universal spinous process clamp mechanisms that are fixed on the chassis, the spinous process clamp mechanism is: be inserted with the activity vertical rod admittedly stand in the tubulose vertical pillars on the chassis, movable rod end is fixed with a horizontally-guided short tube, the movable cross bar front end that passes horizontally-guided short tube vertical fixing again has a laterally steering short tube, the movable clamping bar front end vertical fixing of passing the laterally steering short tube has the spinous process folder, and the hand-tight screw in location is all arranged on the pipe shaft of vertical pillars, horizontally-guided short tube and laterally steering short tube.
Described spinous process folder is made up of the fixedly clip lobe that is fixed on movable clamping bar front end, hinged clip lobe, push rod and hand screw, hinged clip lobe is hinged on fixedly on the clip lobe, after the spiral push rod front end that passes the movable clamping bar of the tubulose with female thread withstood on the clip lobe, the push rod rear end was that hands is twisted nut.
Described elevating bracket is equipped with elevating mechanism, and its structure is equipped with hands and twists dish for tooth bar is made on the surface of column on the elevating bracket, its trunnion axis drive one and tooth bar meshed gears.
The electronics altitude scale that can make zero is housed on the described column, and the liquid crystal prompting screen is installed on the elevating bracket.
Described spinal cord beating system is provided with elastic protection device, and its shape is the reed of bending therefrom, and both ends are all vertically bendings again, and the reed center fixed is in the side of crossbeam cantilever end, and collude above cantilever the bottom, and the upper end is pressed on one's body the bump rod.
Described electric-control system circuit also includes bump contact cue circuit: an end of cue circuit is connected to pilot sleeve, and the signal of bringing in from pilot sleeve inserts single-chip microcomputer, afterwards again through amplifying circuit and be connected with buzzer and display lamp; The other end contacts with animal surgery otch skin edge by electrode, has only when the bump rod touches spinal cord dura mater time side to constitute complete loop.
Described bump rod and pilot sleeve thereof have can be for the different-diameter of changing, the outfit of weight.
Beneficial effect: novel electric-controlled multi-use spinal cord beating device of the present utility model, owing to have spinous process fixture reliable and the corresponding animal that varies in size, so can be applicable to the different genera laboratory animal; Automatically controlled striking bar hits accurately, effectively stable, the electronics scale can accurately be controlled and hit height, bump contact cue circuit makes can produce damage, standardized animal spinal cord damage model in various degree; And anti-error percussion device has been avoided facer.
Description of drawings
The utility model is described in further detail below in conjunction with the drawings and specific embodiments.
Fig. 1 looks sketch map for the master of this utility model embodiment spinal cord beating system.
Fig. 2 is the schematic rear view of Fig. 1.
Fig. 3 is the cross-sectional schematic of Fig. 1.
Fig. 4 is the A-A line cross-sectional schematic along Fig. 3.
Fig. 5 is the schematic perspective view 1 of Fig. 1.
Fig. 6 is the schematic perspective view 2 of Fig. 1.
Fig. 7 is embodiment electric-control system solenoid circuit figure.
Fig. 8 is embodiment electric-control system bump contact cue circuit figure.
Fig. 9 is the animal spinous process fixture schematic perspective view of embodiment.
Figure 10 looks sketch map for animal spinous process fixture master.
Figure 11 is an animal spinous process fixture schematic top plan view.
Figure 12 looks sketch map for an animal spinous process fixture left side.
Figure 13 forms three-dimensional local enlarged diagram for the spinous process clamping structure.
Figure 14 is spinous process folder partial structurtes exploded perspective enlarged diagram.
Figure 15 is the reed enlarged diagram of spinal cord beating system resilience protector.
Figure 16 looks sketch map for the left side of Figure 15.
Among the figure: 1-spinal cord beating system, 2-electric-control system, 3-animal spinous process fixture, the 4-base, 5-column, 6-elevating bracket, 7-clashes into rod, 8-elevating bracket height dog screw, 9-elevating bracket cantilever, 10-clashes into excellent metal pilot sleeve, and the 11-electric magnet is inhaled, 12-spinous process folder, the 14-crossbeam, the 15-tooth bar, the 16-hands is twisted dish, 17-gear, the 18-electronics altitude scale that can make zero, the 19-LCDs, the 20-reed, 301-clip lobe, 302-chassis, the 303-vertical columns, the hand-tight screw of 304-, 305-push rod, 306-push rod hands is twisted nut, 307-activity vertical rod, the movable cross bar of 308-, the movable clamping bar of 309-.
The specific embodiment
From Fig. 1 to Figure 16, can see, novel electric-controlled multi-use spinal cord beating device of the present utility model, comprise spinal cord beating system 1, electric-control system 2 and animal spinous process fixture 3, the spinal cord beating system is made of base 4, column 5, elevating bracket 6 and bump rod 7, elevating bracket can slide up and down to be supported on the column that is fixed on the base, column is two parallel columns, the top has crossbeam to connect, height dog screw 8 is installed on the elevating bracket, and the locking elevating bracket is on column after elevating bracket is elevated to suitable position; Elevating bracket is equipped with elevating mechanism, and its structure is equipped with hands and twists dish 16 for tooth bar 15 is made on the surface of one of column on the elevating bracket, its trunnion axis drive one and tooth bar meshed gears 17.So twist hands twist the dish elevating bracket just can be about column.Cantilever 9 ends that cross out on the elevating bracket are fixed with the excellent metal pilot sleeve 10 of vertical bump, the metal bump rod of top band bulge loop can slide up and down to be through in the pilot sleeve, bump rod and pilot sleeve thereof have can be for the different-diameter of changing, the outfit of weight, as 10g, 20g, 30g, 40g, 50g.
Electric-control system 2 includes control circuit for electromagnet, electric magnet make electromagnetism inhale 11 be installed in pilot sleeve directly over, control circuit for electromagnet is by ac power supply and be provided with power supply indicator, and electromagnetism inhales work during energising, and the top of adsorbable bump rod makes its unlikely falling; When pressing the release-push that is positioned on the base panel, the electric magnet loop is blocked suddenly, and electromagnetism is inhaled and taken over a business to lose absorption affinity, and the bump rod is promptly along the pilot sleeve free falling.Animal spinous process fixture varies in size by two groups, and each one group every group two identical universal spinous process clamp mechanisms of animal are formed by size, and the level of fixture spinal fixation spinal cord is to improve the precision that hits.Referring to Fig. 9 to Figure 14, the composition structure of spinous process clamp mechanism is: be fixed in the tubulose vertical pillars 303 on the chassis 302 and be inserted with activity vertical rod 307, movable rod end is fixed with a horizontally-guided short tube, movable cross bar 308 front ends that pass horizontally-guided short tube vertical fixing again have a laterally steering short tube, the movable clamping bar 309 front end vertical fixing of passing the laterally steering short tube have spinous process folder 12, and the hand-tight screw 304 in location is all arranged on the pipe shaft of vertical pillars, horizontally-guided short tube and laterally steering short tube.The spinous process clamping structure is made up of the fixedly clip lobe that is fixed on movable clamping bar front end and hinged clip lobe 301, push rod and hand screw, hinged clip lobe is hinged on fixedly on the clip lobe, after the spiral push rod front end that passes the movable clamping bar of the tubulose with female thread withstood on hinged clip lobe, the push rod rear end was that hands is twisted nut.When twisting hands when twisting nut, drive push rod and move ahead or retreat, just can make hinged clip lobe clamping or unclamp.
Also can load onto the made zero electronics altitude scale 18 of prior art on column, liquid crystal prompting screen 19 is installed on the elevating bracket, can point out the button that makes zero on the altitude reading precision 0.01mm base with zeroing, and any strike height in the 20cm can be arranged.
Cause accidental injury for avoiding causing the bump rod to fall in the lifting process accidentally; the spinal cord beating system is provided with elastic protection device; its shape is a reed 20 that therefrom bends; both ends are vertically bending again respectively; the reed center fixed is in the side of crossbeam cantilever end; collude above cantilever the bottom, and the upper end is pressed on one's body the bump rod.
The electric-control system circuit also includes bump contact cue circuit: an end of cue circuit is connected to the metal pilot sleeve, and the signal of bringing in from pilot sleeve inserts single-chip microcomputer, afterwards again through amplifying circuit and be connected with buzzer and display lamp; The other end contacts with animal surgery otch skin edge by electrode.Cue circuit has only when the bump rod touches spinal cord dura mater time side and constitutes complete loop.Bump contact cue circuit can be realized tapping the head termination when contacting spinal cord when the bump bastinade, starts buzzer immediately and sends sound and Qi Liang strike display lamp.Also include reset circuit in the circuit.
The using method of this novel electric-controlled multi-use spinal cord beating device and the foundation of animal model make use-case.
To make the Spinal Cord Injury in Rats model is example: get the SD rat, the chloral hydrate lumbar injection dosage with 10% is 3～4ml/kg, and animal enters narcotism behind 5～10min.Hair is shaved at the back, prostrate placing on the operating board, conventional iodophor disinfection art open country, the counting rib is determined breast 10 levels; get the back median incision, be about 2cm, cut skin, subcutaneous successively; be close to vertebral plate and cut and to stay a little muscular tissue to grip in order to spinous process fixation device on the perpendicular spinal muscle spinous process and peel off to the transverse process outside to both sides, appear the 9th～11 lamina of thoracic vertebra.With breast 10 full vertebrae plate resections, note not Spinal Cord with microinstrument, appear dura mater.The spinous process fixation clamp is breast 9, breast 11 spinous process fixedly.Definite bump rod has been adsorbed in upward and with elastic protection device to be fixed, adjust the animal position, the spinal cord window that aligning appears, turning lifting runner on the screw thread column slowly makes the bump bastinade end of tapping the head drop to the dura mater that appears spinal cord and contact gently, at this moment hitting display lamp opens bright and audible buzzer sound, do not turn again, press the button that makes zero of liquid crystal display screen side, this calls zeroing; At the uniform velocity turn again rotating disk be increased to the strike height of drafting can be by behind the reading on the liquid crystal display screen; unclamp elastic protection device; press release-push fast; the heavy 10g of bump rod is promptly along the pilot sleeve free-falling; strike is on the spinal cord that appears; see that promptly the two lower limb of rat twitch rapidly, the tail whipping is loose fully subsequently.Move apart spinal cord and fix with being about to clash into rod, unclamp the spinous process fixation clamp and take out laboratory animal with elastic protection device.As make the spinal cord injury model of monkey or other large animals, and then should select corresponding spinous process fixation device and bump rod for use, step is the same.
Claims (10)
1, a kind of novel electric-controlled multi-use spinal cord beating device, comprise spinal cord beating system (1), it is characterized in that: described spinal cord beating system is made of base (4), column (5), elevating bracket (6) and bump rod (7), the elevating bracket that height dog screw (8) is installed can slide up and down to be supported on the column that is fixed on base, the cantilever that crosses out on the elevating bracket (9) end is fixed with the excellent metal pilot sleeve of vertical bump (10), and the metal bump rod of top band bulge loop can slide up and down to be through in the pilot sleeve; Also include electric-control system (2), it is electric magnet and control circuit thereof, electric magnet make electromagnetism inhale (11) be installed in pilot sleeve directly over, control circuit for electromagnet is by ac power supply.
2, novel electric-controlled multi-use spinal cord beating device according to claim 1, it is characterized in that: include animal spinous process fixture (3), it is made up of at least one group two universal spinous process clamp mechanisms that are fixed on the chassis, the spinous process clamp mechanism is: be fixed in the tubulose vertical pillars on the chassis and be inserted with the activity vertical rod, movable rod end is fixed with a horizontally-guided short tube, the movable cross bar front end that passes horizontally-guided short tube vertical fixing again has a laterally steering short tube, the movable clamping bar front end vertical fixing of passing the laterally steering short tube has spinous process folder (12), vertical pillars, the hand-tight screw in location is all arranged on the pipe shaft of horizontally-guided short tube and laterally steering short tube.
3, novel electric-controlled multi-use spinal cord beating device according to claim 2, it is characterized in that: described spinous process folder is made up of the fixedly clip lobe that is fixed on movable clamping bar front end, hinged clip lobe (301), push rod and hand screw, hinged clip lobe is hinged on fixedly on the clip lobe, after the spiral push rod front end that passes the movable clamping bar of the tubulose with female thread withstood on the clip lobe, the push rod rear end was that the push rod hands is twisted nut (305).
4, novel electric-controlled multi-use spinal cord beating device according to claim 3, it is characterized in that: described elevating bracket is equipped with elevating mechanism, its structure is for to make tooth bar (15) with the surface of one of column, hands is housed on the elevating bracket twists dish (16), its trunnion axis drive one and tooth bar meshed gears (17).
5, novel electric-controlled multi-use spinal cord beating device according to claim 4 is characterized in that: the electronics altitude scale (18) that can make zero is housed on the described column, and liquid crystal prompting screen (19) is installed on the elevating bracket.
6, novel electric-controlled multi-use spinal cord beating device according to claim 5; it is characterized in that: described spinal cord beating system is provided with elastic protection device; its shape is a reed (20) that therefrom bends; both ends are all vertically bendings again; the reed center fixed is in the side of crossbeam cantilever end; collude above cantilever the bottom, and the upper end is pressed on one's body the bump rod.
7, novel electric-controlled multi-use spinal cord beating device according to claim 6 is characterized in that: described column is two parallel columns, and the top has crossbeam (14) to connect.
8, novel electric-controlled multi-use spinal cord beating device according to claim 4; it is characterized in that: described spinal cord beating system is provided with elastic protection device; its shape is a reed (20) that therefrom bends; both ends are all vertically bendings again; the reed center fixed is in the side of crossbeam cantilever end; collude above cantilever the bottom, and the upper end is pressed on one's body the bump rod.
9, novel electric-controlled multi-use spinal cord beating device according to claim 3, it is characterized in that: described electric-control system circuit also includes bump contact cue circuit: an end of cue circuit is connected to pilot sleeve, the signal of bringing in from pilot sleeve inserts single-chip microcomputer, afterwards again through amplifying circuit and be connected with buzzer and display lamp; The other end contacts with animal surgery otch skin edge by electrode, has only when the bump rod touches spinal cord dura mater time side to constitute complete loop.
10, novel electric-controlled multi-use spinal cord beating device according to claim 2, it is characterized in that: described electric-control system circuit also includes bump contact cue circuit: an end of cue circuit is connected to pilot sleeve, the signal of bringing in from pilot sleeve inserts single-chip microcomputer, afterwards again through amplifying circuit and be connected with buzzer and display lamp; The other end contacts with animal surgery otch skin edge by electrode, has only when the bump rod touches spinal cord dura mater time side to constitute complete loop.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007200607700U CN201153990Y (en) | 2007-12-04 | 2007-12-04 | Novel electric control multifunctional spinal cord beating device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007200607700U CN201153990Y (en) | 2007-12-04 | 2007-12-04 | Novel electric control multifunctional spinal cord beating device |
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| CN201153990Y true CN201153990Y (en) | 2008-11-26 |
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| CNU2007200607700U Expired - Lifetime CN201153990Y (en) | 2007-12-04 | 2007-12-04 | Novel electric control multifunctional spinal cord beating device |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101779987A (en) * | 2010-03-16 | 2010-07-21 | 胡建中 | Acute spinal cord injury animal model modeling impactor |
| CN103006333A (en) * | 2012-12-28 | 2013-04-03 | 上海交通大学 | Pelvis impact test device |
| CN103142326A (en) * | 2012-12-14 | 2013-06-12 | 中国科学院自动化研究所 | Electrical control system used for zooperal ventral spinal cord injury impactor |
| CN104739537A (en) * | 2015-04-03 | 2015-07-01 | 绍兴文理学院 | Animal spinal cord injury hitting device |
| CN105796204A (en) * | 2016-05-23 | 2016-07-27 | 戴睿武 | Multifunctional experimental animal impacting machine |
| CN106236309A (en) * | 2016-08-22 | 2016-12-21 | 中国康复研究中心 | A kind of big animal spinal cord moment impact damage model modeling beating device |
| CN106595611A (en) * | 2016-07-29 | 2017-04-26 | 上海市建筑装饰工程集团有限公司 | Support for three-dimensional sample release platform |
| CN108542546A (en) * | 2018-06-26 | 2018-09-18 | 成都市富明珑科技有限责任公司 | A kind of animal spinal cord fixing device |
| CN113739683A (en) * | 2021-11-08 | 2021-12-03 | 深圳市瑞沃德生命科技有限公司 | Zero calibration device, striker with zero calibration device, zero calibration method and striking method |
| CN113893057A (en) * | 2021-09-30 | 2022-01-07 | 中国人民解放军陆军特色医学中心 | Animal injury device capable of switching different impact means |
-
2007
- 2007-12-04 CN CNU2007200607700U patent/CN201153990Y/en not_active Expired - Lifetime
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101779987A (en) * | 2010-03-16 | 2010-07-21 | 胡建中 | Acute spinal cord injury animal model modeling impactor |
| CN101779987B (en) * | 2010-03-16 | 2011-04-06 | 胡建中 | Acute spinal cord injury animal model modeling impactor |
| CN103142326A (en) * | 2012-12-14 | 2013-06-12 | 中国科学院自动化研究所 | Electrical control system used for zooperal ventral spinal cord injury impactor |
| CN103142326B (en) * | 2012-12-14 | 2015-01-07 | 中国科学院自动化研究所 | Electrical control system used for zooperal ventral spinal cord injury impactor |
| CN103006333A (en) * | 2012-12-28 | 2013-04-03 | 上海交通大学 | Pelvis impact test device |
| CN103006333B (en) * | 2012-12-28 | 2014-12-24 | 上海交通大学 | Pelvis impact test device |
| CN104739537A (en) * | 2015-04-03 | 2015-07-01 | 绍兴文理学院 | Animal spinal cord injury hitting device |
| CN105796204A (en) * | 2016-05-23 | 2016-07-27 | 戴睿武 | Multifunctional experimental animal impacting machine |
| CN106595611A (en) * | 2016-07-29 | 2017-04-26 | 上海市建筑装饰工程集团有限公司 | Support for three-dimensional sample release platform |
| CN106236309A (en) * | 2016-08-22 | 2016-12-21 | 中国康复研究中心 | A kind of big animal spinal cord moment impact damage model modeling beating device |
| CN108542546A (en) * | 2018-06-26 | 2018-09-18 | 成都市富明珑科技有限责任公司 | A kind of animal spinal cord fixing device |
| CN113893057A (en) * | 2021-09-30 | 2022-01-07 | 中国人民解放军陆军特色医学中心 | Animal injury device capable of switching different impact means |
| CN113893057B (en) * | 2021-09-30 | 2023-12-01 | 中国人民解放军陆军特色医学中心 | Animal injury device capable of switching different striking means |
| CN113739683A (en) * | 2021-11-08 | 2021-12-03 | 深圳市瑞沃德生命科技有限公司 | Zero calibration device, striker with zero calibration device, zero calibration method and striking method |
| CN113739683B (en) * | 2021-11-08 | 2022-03-15 | 深圳市瑞沃德生命科技有限公司 | Zero calibration device, striker with zero calibration device, zero calibration method and striking method |
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| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Effective date of abandoning: 20071204 |
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| C25 | Abandonment of patent right or utility model to avoid double patenting |