CN201119871Y - Monitoring equipment for acidity basicity of upper digestive tract - Google Patents

Monitoring equipment for acidity basicity of upper digestive tract Download PDF

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Publication number
CN201119871Y
CN201119871Y CNU200720057203XU CN200720057203U CN201119871Y CN 201119871 Y CN201119871 Y CN 201119871Y CN U200720057203X U CNU200720057203X U CN U200720057203XU CN 200720057203 U CN200720057203 U CN 200720057203U CN 201119871 Y CN201119871 Y CN 201119871Y
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operational amplifier
links
resistance
circuit
level
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Expired - Fee Related
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CNU200720057203XU
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Chinese (zh)
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余革
林治川
温晓晖
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FIRST AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL SCHOOL
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FIRST AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL SCHOOL
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Abstract

The utility model provides an acidity-alkalinity monitor equipment of an upper digestive tract, which comprises a pH sensor, an A/D converter and a PC set. The utility model is characterized in that the equipment also comprises a pH value detection circuit, an ECG collection amplification circuit, a micro-control processor, a transformer and an optical coupler, wherein the pH sensor is connected with the pH value detection circuit, the pH value detection circuit, the ECG collection amplification circuit and the micro-control processor are all connected with the PC set through the optical processor. The acidity-alkalinity monitor equipment not only realizes the angina pectoris diagnosis function on the medical clinic but also can be applied in the environment which has bigger electromagnet interference such as the operation room or ICU and the like, which can realize relative work such as the playback of the acidity-alkalinity and the ECG waveshape, tendency analysis and the like.

Description

A kind of upper digestive tract acid-base value custodial care facility
Technical field
This utility model relates to the medical apparatus and instruments field, specifically is meant a kind of upper digestive tract acid-base value monitoring equipment.
Background technology
Patient is when accepting anesthesia and operation; the stimulation of factor such as (as endotracheal intubation) because underlying diseases, operation technique and anaesthetic and anesthesia procedure; regular meeting takes place that gastric content is counter to flow; and patient very easily will instead flow thing mistake and suck respiratory tract under narcotism; cause serious mistake aspiration pneumonitis, jeopardize patient's life security.Therefore, in the anesthesia surgery process, the upper digestive tract acid-base value is monitored in real time very necessary.And up to the present, anaesthetize the upper digestive tract acid-base value monitoring equipment that the boundary does not obtain to be applied to complex electromagnetic environments such as operating room yet both at home and abroad.
At present, can use pH value dynamic monitoring equipment usually to the monitoring of gastroesophageal reflux clinically, patient's upper digestive tract acid-base value is monitored.Promptly the Digestive system generation electrochemical reaction by pH pick off and different pH values produces the correspondent voltage signal, reflects upper gastrointestinal acid-base value information by this voltage signal.The patent No. is that 92202018.3 Chinese utility model patent has been announced a kind of pH value of upper digestive tract dynamic monitor, pH value testing circuit in this device is to carry out A/D conversion by LM331 accurate voltage/frequency converter, implements signal processing and control with single-chip microcomputer again.Because the Electro Magnetic Compatibility of this device is relatively poor, so when being applied to have the operating room environment of a large amount of high power instruments, the large pluse that is easy to be subjected to these instruments interference of electromagnetic signal frequently of leaping high makes the detected value misalignment of pH, can not reflect patient's truth real-time and accurately.Therefore this device can not be applied to the place that operating room or ICU etc. have a large amount of armarium, complex electromagnetic environment.
In addition, the angina pectoris that needs precordialgia that gastroesophageal reflux is caused and coronary heart disease and myocardial ischemia to cause is clinically sometimes differentiated.Gastroenterology dept. can use pH value dynamic monitoring equipment usually to the diagnosis of gastroesophageal reflux, and patient's upper digestive tract acid-base value is monitored.And be Electrocardioscopy to the most frequently used inspection method of anginal diagnosis.Because this device does not possess electrocardiogram collection analysis function, therefore can not accurately differentiate, even cause and fail to pinpoint a disease in diagnosis and mistaken diagnosis the cause of disease of precordialgia.
Summary of the invention
The purpose of this utility model is exactly in order to overcome above-mentioned shortcoming with not enough, a kind of upper digestive tract acid-base value monitoring equipment is provided, this equipment has not only been strengthened Electro Magnetic Compatibility, can be applied under the complex electromagnetic environments such as operating room or ICU, the upper digestive tract acid-base value is carried out real-time monitoring continuously, but also simultaneously collection analysis electrocardiogram and continuous monitoring stomach esophagus pH value, for the Differential Diagnosis to precordialgia clinically provides foundation.
The purpose of this utility model is achieved through the following technical solutions: a kind of upper digestive tract acid-base value custodial care facility, comprise pH pick off, A/D converter and PC, described equipment also comprises pH value testing circuit, electrocardiogram acquisition amplifying circuit, microcontroller processor, transformator and optocoupler; Described pH pick off links to each other with the pH testing circuit, described pH testing circuit, electrocardiogram acquisition amplifying circuit and microcontroller processor all link to each other with A/D converter, described A/D converter links to each other with PC by transformator, and described microcontroller processor links to each other with PC by optocoupler.
Described pH value testing circuit comprises clamping protective circuit, one-level amplifier follow circuit, instrument discharge circuit and step low-pass circuit, and described pH pick off links to each other with clamping protective circuit, one-level amplifier follow circuit, instrument discharge circuit and step low-pass circuit successively.
Described clamping protective circuit is by resistance R 1, R2, capacitor C 1, C2, and crystal diode D1, D2, D3, D4 form; One end of described resistance R 1 links to each other with the pH anelectrode, the other end and operational amplifier U1 AIn-phase input end link to each other, the N level of an end of capacitor C 1, crystal diode D1 and the P level of crystal diode D2 are all and U1 AIn-phase input end link to each other, the other end ground connection of described capacitor C 1, the P level of crystal diode D1 links to each other with-5V power supply, the N level of crystal diode D2 links to each other with+5V power supply; One end of described resistance R 2 links to each other with the pH negative electrode, the other end and operational amplifier U1 BIn-phase input end link to each other, the N level of an end of capacitor C 2, crystal diode D3 and the P level of crystal diode D4 all with operational amplifier U1 BIn-phase input end link to each other, the other end ground connection of described capacitor C 2, the P level of crystal diode D3 links to each other with-5V power supply, the N level of crystal diode D4 links to each other with+5V power supply.
Described one-level amplifier follow circuit is by operational amplifier U1 AAnd operational amplifier U1 BForm; Described operational amplifier U1 AInverting input and U1 AOutfan link to each other, be connected to the in-phase input end of instrument operational amplifier U2, described operational amplifier U1 BInverting input and U1 BOutfan link to each other, be connected to the inverting input of instrument operational amplifier U2.
Described instrument discharge circuit is made up of instrument operational amplifier U2 and resistance R 3; Described resistance R 3 be serially connected with No. 8 of instrument operational amplifier U2 and No. 1 terminal between, No. 5 terminals of described U2 also link to each other with the 1.25V power supply.
Described step low-pass circuit is made up of capacitor C 3, C4, C5, resistance R 4, R5, R6, R7, R8 and operational amplifier U3; Described resistance R 4 is connected with resistance R 5, and the other end of resistance R 4 is connected to the outfan of instrument operational amplifier U2, and the other end of resistance R 5 is connected to the in-phase input end of operational amplifier U3; Capacitor C 3 be connected between resistance R 4 and the R5 after resistance R 7 is connected, the other end of resistance R 7 links to each other with the inverting input of operational amplifier U3, the in-phase input end of an end operational amplifier U3 of capacitor C 4 links to each other, the other end links to each other with the 1.25V power supply; One end of resistance R 6 links to each other with the inverting input of operational amplifier U3, the other end links to each other with the 1.25V power supply, the outfan of described operational amplifier U3 is connected with resistance R 8, links to each other the other end ground connection of capacitor C 5 with A/D converter after the end parallel connection of the other end of resistance R 8 and capacitor C 5.
Described microcontroller processor is Epson 33209.
The using method of upper digestive tract acid-base value custodial care facility of the present utility model is as follows:
(1) the pH pick off is calibrated;
(2) interrupt by the timing of microcontroller processor, start corresponding task, and by SPI USB (universal serial bus) control A/D converter timing sampling pH voltage waveform and ecg wave form;
(3) the microcontroller processor reads the data that the A/D converter sampling obtains;
(4) the microcontroller processor regularly starts electrocardio algorithm and pH voltage waveform analysis algorithm, provides corresponding alarm signal;
(5) the microcontroller processor is issued waveform by serial line interface that PC stores and waveform is play, and accepts the order of PC simultaneously, finishes that cardiac diagnosis lead switches and the order of pH measurement channel selecting.
This utility model has following advantage and effect with respect to prior art:
(1) the utlity model has good anti-electromagnetic interference performance and anti-electric knife jamming performance, be applicable to the upper digestive tract acid-base value monitoring in the operation process;
(2) this utility model can be gathered the pH value voltage waveform and the ecg wave form of upper digestive tract acid-base value simultaneously, has better clinical diagnosis meaning;
(3) input stage of the present utility model has very high input impedance, the variation of the output impedance of dissimilar electrochemistry pH pick offs is very little to influence of the present invention, so the present invention can be applied to as dissimilar electrochemistry pH pick offs such as antimony electrode, glass electrode, the responsive field effect transistor of hydrion;
(4) the utlity model has perfect PC analysis software, existing product generally can only go out a simple report and curve, but PC analysis software of the present invention has the powerful data analysis function, can carry out the real-time demonstration and the related works such as playback and trend analysis of acid-base value and ecg wave form.
Description of drawings
Fig. 1 is an overall structure block diagram of the present utility model;
Fig. 2 is pH value Acquisition Circuit figure of the present utility model.
The specific embodiment
Below in conjunction with embodiment and accompanying drawing this utility model is described in further detail, but embodiment of the present utility model is not limited thereto.
As shown in Figure 1, electrocardiogram acquisition amplifying circuit of the present utility model, pH testing circuit, A/D converter and microcontroller processor are installed on the analog input card, the pH pick off links to each other with the pH testing circuit by holding wire, and pH testing circuit, electrocardiogram acquisition amplifying circuit and microcontroller processor all link to each other with A/D converter by holding wire.Digestive system in pH pick off and the upper digestive tract carries out electrochemical reaction, obtain corresponding pH value voltage signal, obtain the electrocardio pulse signal by the electrocardiogram acquisition amplifying circuit simultaneously, periodic under the control of microcontroller processor this pH value voltage signal and electrocardio pulse signal are input to analysis and the contrast of carrying out waveform in the A/D converter, by optocoupler this pH value voltage signal and electrocardio pulse signal are transferred to PC again, and provide corresponding alarm signal.Medical personnel then can judge that precordialgia is that gastroesophageal reflux causes or coronary heart disease and myocardial ischemia causes by real-time demonstration on the PC and playback function.And transformator links to each other with power supply chip on the analog input card, and the insulating power supply of low noise is provided for all power devices on the analog input card.Optocoupler is as the intermediary between microcontroller processor and the PC, both isolated with the microcontroller processor and with PC, again the information transmission of microcontroller processor is given PC and finished waveform and show and the data memory function, simultaneously also can carry out remote monitoring by the Internet, can guarantee patient's safety so on the one hand, can reduce on the other hand since the power frequency that ground wire causes to the interference of analog front end circuit.
As shown in Figure 2, pH Acquisition Circuit of the present utility model is made of jointly pH pick off, clamping protective circuit, one-level amplifier follow circuit, instrument discharge circuit and step low-pass circuit.The pH pick off links to each other with pH electrode, and described pH positive electricity is measurement electrode very, and the pH negative electricity is reference electrode very.When pH pick off during with different Digestive system generation electrochemical reaction; can produce corresponding very faint pH value voltage signal, other big interfering signals that the large pluse that this pH value voltage signal produces when carrying out electric knife surgical operation or defibrillation is leapt high in frequency interference signal and the operating room enter clamping protective circuit together.Under these large pluses are leapt high the effect of frequency interference signal; crystal diode D1 in the clamping protective circuit, D2, D3, D4 are switched on; metering function through current-limiting resistance R1 and R2; thereby limited the leap high amplitude of frequency interference signal of this large pluse; simultaneously; current-limiting resistance R1 and capacitor C 1; current-limiting resistance R2 and capacitor C 2 have all constituted a low pass filter; the coupled high-frequency interferencing signal of front end is effectively decayed; leap high frequency interference signal to the influence of Acquisition Circuit thereby reduce this large pluse, protection pH value Acquisition Circuit.
Since very faint from the voltage signal of clamping protective circuit output, so need separate and extract processing to the pH value voltage signal in this voltage signal.By operational amplifier U1 A, U1 BThe one-level amplifier follow circuit of forming has the impedance of G Europe level and the input bias current of P peace level, so this one-level amplifier follow circuit can farthest extract the pH value voltage signal, and can reduce this pressure drop of pH value voltage signal in the pick off internal resistance.
The voltage signal of process one-level follow circuit output enters the instrument discharge circuit again and handles, this instrument discharge circuit adopts the instrument operational amplifier that this voltage signal is amplified, make this pH value voltage signal reach the sample range of A/D converter, because the instrument amplifier has very high input impedance and good common mode inhibition capacity, therefore can eliminate the influence of front end common-mode noise significantly.
Second-order low-pass filter circuit of the common composition of resistance R 4, R5, R6, R7, R8 and capacitor C 3, C4, C5 and operational amplifier U3, enter the in-phase input end of operational amplifier U3 after through resistance R 4, R5 from the voltage of instrument discharge circuit output, because this step low-pass circuit can be with the influence of 40DB/10 frequency multiplication ground weakening zone external noise, so this pH value voltage waveform further can be amplified and give analog-digital converter and sample.
The using method of upper digestive tract acid-base value custodial care facility of the present utility model is as follows:
(1) the pH pick off is calibrated;
(2) interrupt by the timing of microcontroller processor, start corresponding task, and by SPI USB (universal serial bus) control A/D converter timing sampling pH voltage waveform and ecg wave form;
(3) the microcontroller processor reads the data that the A/D converter sampling obtains;
(4) the microcontroller processor regularly starts electrocardio algorithm and pH voltage waveform analysis algorithm, provides corresponding alarm signal;
(5) the microcontroller processor is issued waveform by serial line interface that PC stores and waveform is play, and accepts the order of PC simultaneously, finishes that cardiac diagnosis lead switches and the order of pH measurement channel selecting.

Claims (7)

1, a kind of upper digestive tract acid-base value custodial care facility comprises pH pick off, A/D converter and PC, it is characterized in that: described equipment also comprises pH value testing circuit, electrocardiogram acquisition amplifying circuit, microcontroller processor, transformator and optocoupler; Described pH pick off links to each other with the pH testing circuit, described pH testing circuit, electrocardiogram acquisition amplifying circuit and microcontroller processor all link to each other with A/D converter, described A/D converter links to each other with PC by transformator, and described microcontroller processor links to each other with PC by optocoupler.
2, a kind of upper digestive tract acid-base value custodial care facility according to claim 1; it is characterized in that: described pH value testing circuit comprises clamping protective circuit, one-level amplifier follow circuit, instrument discharge circuit and step low-pass circuit, and described pH pick off links to each other with clamping protective circuit, one-level amplifier follow circuit, instrument discharge circuit and step low-pass circuit successively.
3, a kind of upper digestive tract acid-base value custodial care facility according to claim 2 is characterized in that: described clamping protective circuit is by resistance R 1, R2, capacitor C 1, C2, and crystal diode D1, D2, D3, D4 form; One end of described resistance R 1 links to each other with the pH anelectrode, the other end and operational amplifier U1 AIn-phase input end link to each other, the N level of an end of capacitor C 1, crystal diode D1 and the P level of crystal diode D2 are all and U1 AIn-phase input end link to each other, the other end ground connection of described capacitor C 1, the P level of crystal diode D1 links to each other with-5V power supply, the N level of crystal diode D2 links to each other with+5V power supply; One end of described resistance R 2 links to each other with the pH negative electrode, the other end and operational amplifier U1 BIn-phase input end link to each other, the N level of an end of capacitor C 2, crystal diode D3 and the P level of crystal diode D4 all with operational amplifier U1 BIn-phase input end link to each other, the other end ground connection of described capacitor C 2, the P level of crystal diode D3 links to each other with-5V power supply, the N level of crystal diode D4 links to each other with+5V power supply.
4, a kind of upper digestive tract acid-base value custodial care facility according to claim 2, it is characterized in that: described one-level amplifier follow circuit is by operational amplifier U1 AAnd operational amplifier U1 BForm; Described operational amplifier U1 AInverting input and U1 AOutfan link to each other, be connected to the in-phase input end of instrument operational amplifier U2, described operational amplifier U1 BInverting input and U1 BOutfan link to each other, be connected to the inverting input of instrument operational amplifier U2.
5, a kind of upper digestive tract acid-base value custodial care facility according to claim 2, it is characterized in that: described instrument discharge circuit is made up of instrument operational amplifier U2 and resistance R 3; Described resistance R 3 be serially connected with No. 8 of instrument operational amplifier U2 and No. 1 terminal between, No. 5 terminals of described U2 also link to each other with the 1.25V power supply.
6, a kind of upper digestive tract acid-base value custodial care facility according to claim 2, it is characterized in that: described step low-pass circuit is made up of capacitor C 3, C4, C5, resistance R 4, R5, R6, R7, R8 and operational amplifier U3; Described resistance R 4 is connected with resistance R 5, and the other end of resistance R 4 is connected to the outfan of instrument operational amplifier U2, and the other end of resistance R 5 is connected to the in-phase input end of operational amplifier U3; Capacitor C 3 be connected between resistance R 4 and the R5 after resistance R 7 is connected, the other end of resistance R 7 links to each other with the inverting input of operational amplifier U3, the in-phase input end of an end operational amplifier U3 of capacitor C 4 links to each other, the other end links to each other with the 1.25V power supply; One end of resistance R 6 links to each other with the inverting input of operational amplifier U3, the other end links to each other with the 1.25V power supply, the outfan of described operational amplifier U3 is connected with resistance R 8, links to each other the other end ground connection of capacitor C 5 with A/D converter after the end parallel connection of the other end of resistance R 8 and capacitor C 5.
7, a kind of upper digestive tract acid-base value custodial care facility according to claim 1, it is characterized in that: described microcontroller processor is Epson 33209.
CNU200720057203XU 2007-09-20 2007-09-20 Monitoring equipment for acidity basicity of upper digestive tract Expired - Fee Related CN201119871Y (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105054931A (en) * 2015-09-18 2015-11-18 重庆金山科技(集团)有限公司 System for automatically detecting gastroesophageal reflux event
WO2016014756A1 (en) * 2014-07-24 2016-01-28 Atlas Scientific LLC Electrochemical sensing module

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016014756A1 (en) * 2014-07-24 2016-01-28 Atlas Scientific LLC Electrochemical sensing module
US9571121B2 (en) 2014-07-24 2017-02-14 Atlas Scientific LLC Electrochemical sensing module
GB2544669A (en) * 2014-07-24 2017-05-24 Atlas Scient Llc Electrochemical sensing module
JP2017527789A (en) * 2014-07-24 2017-09-21 アトラス サイエンティフィック リミティッド ライアビリティ カンパニー Sensor detection circuit and sensor reading acquisition method
GB2544669B (en) * 2014-07-24 2021-06-09 Atlas Scient Llc Electrochemical sensing module
CN105054931A (en) * 2015-09-18 2015-11-18 重庆金山科技(集团)有限公司 System for automatically detecting gastroesophageal reflux event

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C17 Cessation of patent right
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Granted publication date: 20080924

Termination date: 20091020