CN103417208B - Atrial fibrillation detection device - Google Patents
Atrial fibrillation detection device Download PDFInfo
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- CN103417208B CN103417208B CN201310297015.4A CN201310297015A CN103417208B CN 103417208 B CN103417208 B CN 103417208B CN 201310297015 A CN201310297015 A CN 201310297015A CN 103417208 B CN103417208 B CN 103417208B
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- atrial fibrillation
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Abstract
The invention discloses an atrial fibrillation detection device and detection method. The atrial fibrillation detection device can be placed in places such as a house of a patient or an office of the patient. Only one atrial fibrillation detection device can accurately detect whether atrial fibrillation happens or not, and other detection devices are not required to be matched with the atrial fibrillation detection device. A computer inputs detected digital electrocardio signals into a stochastic resonance model, resonance is generated by the stochastic resonance model, and the computer computes an output SNR of the stochastic resonance model, extracts the SNR mean value and the SNR maximum value of atrial fibrillation characteristics from the digital electrocardio signals, further makes the judgment on whether the atrial fibrillation happens or not, and timely gives out safety information or alarm information. According to the atrial fibrillation detection device and detection method, the electrocardio signals can be detected at any time, the alarm information can be timely given out, and the atrial fibrillation detection device has the advantages of being high in detection efficiency and good in accuracy.
Description
Technical field
The present invention relates to electrocardiogram (ECG) signal analysis technology field, especially relate to a kind of atrial fibrillation checkout gear and the detection method that can accurately extract atrial fibrillation feature from electrocardiosignal.
Background technology
Conventionally, it is once excited that human body is sent by sinuatrial node, by certain approach and process, is transmitted to successively atrium and ventricle, causes the excitement of whole heart; Therefore,, in each cardiac cycle, there are certain rule electric change propagation direction, approach, order and the time etc. that in heart each several part process of excitation, occur.This bio electricity changes by heart conductive tissue and body fluid around, is reflected to body surface, makes parts of body that regular electricity also all occur in each cardiac cycle and changes.Measurement electrode is placed on to the cardiac electric change curve that certain position of human body surface records out, is exactly the electrocardiogram (electrocardiogram, ECG) of record clinically.The signal that comprises reflection patient atrial activity in the body surface ecg of patients with atrial fibrillation, for example, containing abundant relevant patient atrium feature structure and the information of Pathophysiology situation in Atrial Fibrillation Waves, have clinically very large application potential.
Atrial fibrillation is called for short atrial fibrillation, is modal perpetual arrhythmia, and the total sickness rate of atrial fibrillation is 0.4%, and the incidence rate of atrial fibrillation constantly increases with age, and within 75 years old, above crowd can reach 10%.During atrial fibrillation, the frequency of atrium excitement reaches 300 beats/min to 600 beats/min, palmic rate is often fast and irregular, sometimes can reach 100 beats/min to 160 beats/min, not only faster than normal person heart beating, and absolutely not neat, atrium loses effective contractile function.
China's large-scale survey studies show that atrial fibrillation prevalence is 0.77%.Although atrial fibrillation directly causes patient's death unlike quivering in chamber, but during atrial fibrillation, Ventricular Rate can cause that hemodynamics worsens fast, cause cardiac function infringement and malignant ventricular arrhythmia, especially merging thromboembolism will increase patient and occur the danger of apoplexy greatly.At present, owing to can not find, follow the tracks of the change of state of atrial fibrillation and the Validity Test method of therapeutic effect, the improvement of atrial fibrillation is all based on clinical trial-and-error method substantially, causes the decline of therapeutic efficiency.
But, read electrocardiogram, and according to the variation of waveform, to judge be a very complicated process, usually can there is due to the deficiency of doctor's qualification and experience Electrocardiographic interpretation mistake.
Chinese patent mandate publication number: CN101785669A, authorizes open day on July 28th, 2010, discloses a kind of electrocardiograph signal detection method, comprises the steps: signal extraction step, extracts measured's electrocardiosignal and acoustical signal simultaneously; ECG signal sampling step, process described electrocardiosignal, to obtain electrocardiosignal characteristic parameter, and establishing criteria limit value judges that described electrocardiosignal characteristic parameter is whether within the scope of standard limited value, if within the scope of described standard limited value, finish described ECG signal sampling, if not within the scope of described standard limited value, enter acoustical signal detecting step; And acoustical signal detecting step, process described acoustical signal, and judge that whether described acoustical signal is abnormal, if normal, determine that described electrocardiosignal characteristic parameter is not within the scope of standard limited value, if abnormal, the result within the scope of described standard limited value is not undetermined for described electrocardiosignal characteristic parameter.Weak point is that this invention function singleness, can not be for extracting atrial fibrillation feature.
Summary of the invention
The present invention is difficult to catch in order to overcome atrial fibrillation feature of the prior art, and testing process is complicated, the time is long, and the deficiency that diagnostic accuracy is low, provides a kind of atrial fibrillation checkout gear and the detection method that can accurately extract atrial fibrillation feature from electrocardiosignal.
To achieve these goals, the present invention is by the following technical solutions:
A kind of atrial fibrillation checkout gear, atrial fibrillation checkout gear is electrically connected to computer, comprise housing, be located at ECG detector, digital signal processor, display in housing, be located at the alarm on housing, right lower limb detecting electrode, right arm detecting electrode and left arm detecting electrode; Digital signal processor is electrically connected to ECG detector, and digital signal processor, display and alarm are electrically connected to computer respectively, and right lower limb detecting electrode, right arm detecting electrode and left arm detecting electrode are electrically connected to ECG detector respectively.
As Fig. 1 (a) be normal person electrocardiogram, electrocardiogram that Fig. 1 (b) is patients with atrial fibrillation; Shown in Fig. 1 (b), the electrocardiogram of patients with atrial fibrillation is usually expressed as: P ripple disappear replace little and irregular f ripple and Ventricular Rate definitely uneven.Wherein, the absolute uneven great majority of Ventricular Rate are caused by atrial fibrillation.
But, on electrocardiogram, without P ripple, but also without f ripple clearly, how, because atrium obviously expands and serious fibrosis causes f ripple minimum, be difficult for finding.Need to carry out further intracardiac electrophysiology inspection, could determine that it belongs to atrial fibrillation, atrium partial paralysis or atrium paralysis.
Therefore, common atrial fibrillation diagnosis needs a complicated testing process, according to electrocardiogram, can't make atrial fibrillation diagnosis, need to proceed a series of subsequent detection, and whether just can make is the diagnosis of atrial fibrillation.
And atrial fibrillation needs timely diagnosis and treatment while occurring, otherwise will produce serious result, even can lose one's life.
Atrial fibrillation checkout gear of the present invention can be placed on the places such as patient Jia Zhonghuo office, and whether an atrial fibrillation checkout gear can accurately detect has atrial fibrillation to occur, and does not need the cooperation of other checkout equipment.
Patient can detect electrocardiosignal at any time, in digital electrocardiosignal input accidental resonance model, makes accidental resonance model produce resonance; Computer utilizes formula
calculate the output signal-to-noise ratio of accidental resonance model, it is the meansigma methods SNR of the output signal-to-noise ratio within the scope of 1 to 250dB that computer calculates excitation noise
on average; The SNR of computer selecting output signal-to-noise ratio curve
maximum, computer calculates | SNR
maximum-SNR
on average|;
When | SNR is average |≤W
1, and | SNR
maximum-SNR
on average|≤W
2, computer control alarm sends safety information;
| SNR is average |≤W
1, and | SNR
maximum-SNR
on average| > W
2, computer controlled display display alarm information, alarm sends warning message;
When | SNR is average | > W
1, and | SNR
maximum-SNR
on average|≤W
2, computer control alarm sends safety information;
| SNR is average | > W
1, and | SNR
maximum-SNR
on average| > W
2, computer controlled display display alarm information, alarm sends warning message.
Through above-mentioned processing, computer from digital electrocardiosignal by atrial fibrillation feature SNR
on averageand SNR
maximumaccurately extract, make the judgement whether atrial fibrillation occurs, and send in time warning message.
Use atrial fibrillation checkout gear of the present invention, patient does not spend hospital can detect electrocardiosignal, effectively prevents that atrial fibrillation signal is undetected, for the timely diagnosis and treatment of patients with atrial fibrillation, has striven for the quality time, effectively guarantees the life security of patients with atrial fibrillation.
As preferably, described ECG detector comprises inverting amplifier, voltage follower and INA114 voltage comparator; Described right arm detecting electrode and left arm detecting electrode are electrically connected to negative input end and the positive input terminal of voltage comparator respectively by shielding line, and the outfan of voltage comparator is electrically connected to computer.
As preferably, described voltage comparator is INA114 chip, between the 1st pin of voltage comparator and the 8th pin, be provided with two resistance that resistance is identical, the junction of two resistance is electrically connected to the positive input terminal of voltage follower, the negative input end of voltage follower is electrically connected to the outfan of voltage follower, the outfan of voltage follower is electrically connected to the radome of shielding line, the outfan of voltage follower is electrically connected to the negative input end of inverting amplifier, and the outfan of inverting amplifier is electrically connected to right lower limb detecting electrode.
As preferably, described inverting amplifier comprises 1/2OPA2604 chip and the input resistance, output resistance and the feedback resistance that are electrically connected to 1/2OPA2604 chip respectively.
A detection method for atrial fibrillation checkout gear, comprises the steps:
(5-1) with the detection position of alcohol wipe measured's left arm, right arm and right lower limb, carry out disinfection, 3 electrodes are placed on respectively to detect on position and detect, ECG detector obtains analog electrocardiogram signal;
(5-2) in digital signal processor, be provided with accidental resonance model
wherein, V (x) is non-linear potential function, and ξ (t) is white Gaussian noise, and α is constant, f
0be frequency modulating signal, D is noise intensity;
In digital signal processor, be provided with mould/number conversion module; Mould/number conversion module is transformed to digital electrocardiosignal I (t) by analog electrocardiogram signal;
(5-3) in computer, be provided with secure threshold W
1with alarm threshold value W
2, in digital electrocardiosignal I (t) input accidental resonance model, accidental resonance model produces resonance;
(5-4) computer utilizes formula
the output signal-to-noise ratio that calculates accidental resonance model, wherein, ω is signal frequency, and Ω is angular frequency, and S (ω) is signal spectral density, S
n(Ω) be the noise intensity in signal frequency range;
(5-5) computer draws the output signal-to-noise ratio curve of accidental resonance model, and calculates the meansigma methods SNR that excitation noise is the output signal-to-noise ratio within the scope of 1 to 250dB
on average;
(5-6) SNR of computer selecting output signal-to-noise ratio curve
maximum, and calculate | SNR
maximum-SNR
on average|;
(5-7) when | SNR is average |≤W
1, and | SNR
maximum-SNR
on average|≤W
2, computer control alarm sends safety information;
| SNR is average |≤W
1, and | SNR
maximum-SNR
on average| > W
2, computer controlled display display alarm information, alarm sends warning message;
When | SNR is average | > W
1, and | SNR
maximum-SNR
on average|≤W
2, computer control alarm sends safety information;
| SNR is average | > W
1, and | SNR
maximum-SNR
on average| > W
2, computer controlled display display alarm information, alarm sends warning message.
As preferably, described W
1for 10dB to 22dB.
As preferably, described W
2for 5dB to 10dB.
Therefore, the present invention has following beneficial effect: (1) can detect electrocardiosignal at any time, sends in time warning message; (2) can from electrocardiosignal, extract effective atrial fibrillation feature; (3) detection efficiency is high, accuracy good.
Accompanying drawing explanation
Fig. 1 is the comparison diagram of normal electrocardiosignal and atrial fibrillation electrocardiosignal;
Fig. 2 is a kind of schematic diagram of ECG detector of the present invention;
Fig. 3 is a kind of theory diagram of the present invention;
Fig. 4 is a kind of flow chart of the present invention;
Fig. 5 is output signal-to-noise ratio curve chart of the present invention.
In figure: housing 1, ECG detector 2, digital signal processor 3, display 4, alarm 5, right lower limb detecting electrode 6, right arm detecting electrode 7, left arm detecting electrode 8, inverting amplifier 9, voltage follower 10, voltage comparator 11, shielding line 12, radome 13, measured 14, computer 15, normal person's electrocardiogram a, patients with atrial fibrillation electrocardiogram b.
The specific embodiment
Below in conjunction with the drawings and specific embodiments, the present invention will be further described.
Embodiment is as shown in Figure 3 a kind of atrial fibrillation checkout gear, atrial fibrillation checkout gear is electrically connected to computer 15, comprise housing 1, be located at ECG detector 2, digital signal processor 3, display 4 in housing, be located at the alarm 5 on housing, right lower limb detecting electrode 6, right arm detecting electrode 7 and left arm detecting electrode 8; Digital signal processor is electrically connected to ECG detector, and digital signal processor, display and alarm are electrically connected to computer respectively, and right lower limb detecting electrode, right arm detecting electrode and left arm detecting electrode are electrically connected to ECG detector respectively.
As shown in Figure 2, ECG detector comprises inverting amplifier 9, voltage follower 10 and voltage comparator 11; Right arm detecting electrode and left arm detecting electrode are electrically connected to negative input end and the positive input terminal of voltage comparator respectively by shielding line 12, and the outfan of voltage comparator is electrically connected to computer;
Between the 1st pin of INA114 voltage comparator and the 8th pin, be provided with two resistance that resistance is identical, the junction of two resistance is electrically connected to the positive input terminal of voltage follower, the negative input end of voltage follower is electrically connected to the outfan of voltage follower, the outfan of voltage follower is electrically connected to the radome of shielding line 13, the outfan of voltage follower is electrically connected to the negative input end of inverting amplifier, and the outfan of inverting amplifier is electrically connected to right lower limb detecting electrode.Inverting amplifier comprises OPA2604 chip and the input resistance, output resistance and the feedback resistance that are electrically connected to OPA2604 chip respectively.
As shown in Figure 4, a kind of detection method of atrial fibrillation checkout gear, comprises the steps:
Step 100, with the detection position of alcohol wipe measured 14 left arm, right arm and right lower limb, carry out disinfection, right lower limb detecting electrode, right arm detecting electrode and left arm detecting electrode are placed on respectively to detect on position and detect, ECG detector obtains analog electrocardiogram signal;
Step 200, is provided with accidental resonance model in digital signal processor
wherein, V (x) is non-linear potential function, and ξ (t) is white Gaussian noise, and α is constant, f
0be frequency modulating signal, D is noise intensity;
In digital signal processor, be provided with mould/number conversion module; Mould/number conversion module is transformed to digital electrocardiosignal I (t) by analog electrocardiogram signal;
Step 300, is provided with secure threshold W in computer
1with alarm threshold value W
2, in digital electrocardiosignal I (t) input accidental resonance model, accidental resonance model produces resonance; W
1=22dB, W
2=10dB;
Step 400, computer utilizes formula
the output signal-to-noise ratio that calculates accidental resonance model, wherein, ω is signal frequency, and Ω is angular frequency, and S (ω) is signal spectral density, S
n(Ω) be the noise intensity in signal frequency range;
Step 500, computer draws the output signal-to-noise ratio curve of accidental resonance model, and calculates the meansigma methods SNR that excitation noise is the output signal-to-noise ratio within the scope of 1 to 250dB
on average;
As shown in Figure 5, the SNR of the output signal-to-noise ratio of the present embodiment
on average=-51.8dB;
Step 600, the SNR of computer selecting output signal-to-noise ratio curve
maximum, and calculate | SNR
maximum-SNR
on average|;
The SNR of the output signal-to-noise ratio curve of the present embodiment
maximum=-45dB;
Step 700, when | SNR
on average|≤W
1, and | SNR
maximum-SNR
on average|≤W
2, computer control alarm sends safety information;
| SNR
on average|≤W
1, and | SNR
maximum-SNR
on average| > W
2, computer controlled display display alarm information, alarm sends warning message;
When | SNR
on average| > W
1, and | SNR
maximum-SNR
on average|≤W
2, computer control alarm sends safety information;
| SNR
on average| > W
1, and | SNR
maximum-SNR
on average| > W
2, computer controlled display display alarm information, alarm sends warning message.
In the present embodiment, | SNR
maximum-SNR
on average|=6.8dB.Computer control alarm sends safety information.
Should be understood that the present embodiment is only not used in and limits the scope of the invention for the present invention is described.In addition should be understood that those skilled in the art can make various changes or modifications the present invention after having read the content of the present invention's instruction, these equivalent form of values fall within the application's appended claims limited range equally.
Claims (4)
1. an atrial fibrillation checkout gear, atrial fibrillation checkout gear is electrically connected to computer (15), it is characterized in that, comprise housing (1), be located at ECG detector (2), digital signal processor (3), display (4) in housing, be located at alarm (5), right lower limb detecting electrode (6), right arm detecting electrode (7) and left arm detecting electrode (8) on housing; Digital signal processor is electrically connected to ECG detector, and digital signal processor, display and alarm are electrically connected to computer respectively, and right lower limb detecting electrode, right arm detecting electrode and left arm detecting electrode are electrically connected to ECG detector respectively;
With the detection position of left arm, right arm and the right lower limb of alcohol wipe measured (14), carry out disinfection, 3 electrodes are placed on respectively to detect on position and detect, ECG detector obtains analog electrocardiogram signal;
In digital signal processor, be provided with accidental resonance model
wherein, V (x) is non-linear potential function, and ξ (t) is white Gaussian noise, and a is constant, f
0be frequency modulating signal, D is noise intensity;
In digital signal processor, be provided with mould/number conversion module; Mould/number conversion module is transformed to digital electrocardiosignal I (t) by analog electrocardiogram signal;
In computer, be provided with secure threshold W
1with alarm threshold value W
2, in digital electrocardiosignal I (t) input accidental resonance model, accidental resonance model produces resonance;
Computer utilizes formula
the output signal-to-noise ratio that calculates accidental resonance model, wherein, ω is signal frequency, and Ω is angular frequency, and S (ω) is signal spectral density, S
n(Ω) be the noise intensity in signal frequency range;
Computer draws the output signal-to-noise ratio curve of accidental resonance model, and calculates the meansigma methods SNR that excitation noise is the output signal-to-noise ratio within the scope of 1 to 250dB
on average;
The SNR of computer selecting output signal-to-noise ratio curve
maximum, and calculate | SNR
maximum-SNR
on average|;
When | SNR
on average|≤W
1, and | SNR
maximum-SNR
on average|≤W
2, computer control alarm sends safety information;
| SNR
on average|≤W
1, and | SNR
maximum-SNR
on average| > W
2, computer controlled display display alarm information, alarm sends warning message;
When | SNR
on average| > W
1, and | SNR
maximum-SNR
on average|≤W
2, computer control alarm sends safety information;
| SNR
on average| > W
1, and | SNR
maximum-SNR
on average| > W
2, computer controlled display display alarm information, alarm sends warning message.
2. atrial fibrillation checkout gear according to claim 1, is characterized in that, described ECG detector comprises inverting amplifier (9), voltage follower (10) and voltage comparator (11); Described right arm detecting electrode and left arm detecting electrode are electrically connected to negative input end and the positive input terminal of voltage comparator respectively by shielding line (12), and the outfan of voltage comparator is electrically connected to computer.
3. atrial fibrillation checkout gear according to claim 2, it is characterized in that, described voltage comparator is INA114 chip, between the 1st pin of voltage comparator and the 8th pin, be provided with two resistance that resistance is identical, the junction of two resistance is electrically connected to the positive input terminal of voltage follower, the negative input end of voltage follower is electrically connected to the outfan of voltage follower, the outfan of voltage follower is electrically connected to the radome of shielding line (13), the outfan of voltage follower is electrically connected to the negative input end of inverting amplifier, the outfan of inverting amplifier is electrically connected to right lower limb detecting electrode.
4. atrial fibrillation checkout gear according to claim 2, is characterized in that, described inverting amplifier comprises OPA2604 chip and the input resistance, output resistance and the feedback resistance that are electrically connected to OPA2604 chip respectively.
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|---|---|---|---|
| CN201310297015.4A CN103417208B (en) | 2013-07-12 | 2013-07-12 | Atrial fibrillation detection device |
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|---|---|---|---|
| CN201310297015.4A CN103417208B (en) | 2013-07-12 | 2013-07-12 | Atrial fibrillation detection device |
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| CN103417208B true CN103417208B (en) | 2014-12-10 |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104323772B (en) * | 2014-12-02 | 2016-08-24 | 太原理工大学 | A kind of atrial fibrillation method for extracting signal based on sparse component analysis |
| DE112016005886T5 (en) * | 2015-12-22 | 2018-08-30 | The Regents Of The University Of California | Computational localization of fibrillation sources |
| CN109480819A (en) * | 2017-09-11 | 2019-03-19 | 南京大学 | A method of atrial fibrillation is predicted using multichannel body surface ecg |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101264016A (en) * | 2004-08-27 | 2008-09-17 | 欧姆龙健康医疗事业株式会社 | Portable type electrocardiograph |
| CN201537088U (en) * | 2009-11-26 | 2010-08-04 | 马慧彬 | Portable electrocardiograph |
| CN103110416A (en) * | 2013-03-04 | 2013-05-22 | 江南大学 | Remote electrocardio intelligent monitoring system |
-
2013
- 2013-07-12 CN CN201310297015.4A patent/CN103417208B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101264016A (en) * | 2004-08-27 | 2008-09-17 | 欧姆龙健康医疗事业株式会社 | Portable type electrocardiograph |
| CN201537088U (en) * | 2009-11-26 | 2010-08-04 | 马慧彬 | Portable electrocardiograph |
| CN103110416A (en) * | 2013-03-04 | 2013-05-22 | 江南大学 | Remote electrocardio intelligent monitoring system |
Non-Patent Citations (3)
| Title |
|---|
| Burr-Brown Corporation.Dual FET-Input, Low Distortion OPERATIONAL AMPLIFIER.《OPA26004 Dual FET-Input,Low Distortion OPERATIONAL AMPLIFIER》.1997, * |
| 刘江一等.精密仪用放大器INA114.《ELECTRONIC PRODUCTS CHINA》.2001,13-15. * |
| 精密仪用放大器INA114;刘江一等;《ELECTRONIC PRODUCTS CHINA》;20011130;13-15 * |
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