CN201086012Y - Microcapsule granulation system - Google Patents
Microcapsule granulation system Download PDFInfo
- Publication number
- CN201086012Y CN201086012Y CNU2007200458551U CN200720045855U CN201086012Y CN 201086012 Y CN201086012 Y CN 201086012Y CN U2007200458551 U CNU2007200458551 U CN U2007200458551U CN 200720045855 U CN200720045855 U CN 200720045855U CN 201086012 Y CN201086012 Y CN 201086012Y
- Authority
- CN
- China
- Prior art keywords
- auxiliary material
- granulation
- bag
- granulation tower
- granulating system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Abstract
The utility model relates to a microencapsulation and granulation system which comprises a granulation tower, a slurry supply pipe, a fluidized dryer, a final product chamber, a coating material chamber and a feeding mechanism. The coating materials are fed into the granulation tower from the bottom of the coating material chamber via the feeding mechanism. The slurry is fed into a granulating head via the slurry supply pipe and then spun inside the granulation tower to form thousands of spherical liquid beads. The spherical liquid beads are coated by the coating material to remove water content, forming microencapsulated granules. The microencapsulated granules and most of the coating materials fall into the fluidized dryer where they are further dried and the microencapsulated granules are separated from the coating materials. The coating materials are fed into the coating material chamber for cyclic utilization, and the microencapsulated granules are delivered to the final product chamber. The utility model realizes the drying and granulation with coating materials. For the common materials, the coating material is heated to a certain temperature by hot air prior to granulation. For heat-sensible easily-oxidized materials, the low-temperature granulation is provided. The utility model has the advantages of good grain roundness and good granulation effect.
Description
Technical field
The utility model relates to a kind of microcapsule granulating system.
Background technology
Microcapsule technology is a kind of technology of utilizing natural or synthetic macromolecule filming material (wall material) liquid or solid medicine (capsule material) to be wrapped embedding formation diameter 100～5000 μ m tiny capsules particles.
The process of preparation microcapsule granule is called the abbreviation microencapsulation.Be widely used in industries such as auxiliary agent, intermediate, medicine, agricultural chemicals, food, environmental protection, petrochemical industry, fine chemistry industry, basic organic chemical industry.Have many superiority after the medicament microcapsuleization:
1. can reduce the incompatibility between the compound preparation Chinese traditional medicine, the reaction between isolated drug component.
2. cover the bitter taste or the peculiar smell of medicine, as sulfa drugs.
3. the release of control medicine.
(1) controlled release or slow releasing pharmaceutical can adopt inert membrane, biodegradable material to wait the effect that reaches controlled release or slowly-releasing.
(2) medicine is discharged at specific position, the medicine lower for therapeutic index can be made into targeting preparation, improves the curative effect of medicine.
4. reduce the toxicity of medicine.
5. the pharmaceutical preparation with the micro-capsule preparation has following superiority:
(1) controlled release or slow releasing pharmaceutical.Prepare powder with microcapsule granule, good fluidity, dosage is more accurate.Can improve the easy hygroscopicity of medicine, prevented from caking.
(2) pour into Capsules with microcapsule granule, good fluidity, loading amount is accurate.
(3) can directly use the microcapsule granule compressed tablets, compressibility is good.Mobility of particle is good, and the amount of inserting punch die is accurate, and tablet weight variation is less; Powder flies upward in the time of also can reducing compressing tablet.
6. protection medicine is as easy oxidation, to medicines such as aqueous vapor sensitivities; Make liquid state or volatile medicine become stable powder.
7. be more conducive to the storage of medicine.
The equipment that present stage is used for microencapsulation preparation has only the high-temperature spray method a kind of, the high commute oxidation of EAT heat sensitive material incompatibility, and coating rate is not high, and easy broken wall influences the result of use of medicine or other active ingredients.The equipment of granular material being made small particles material also has the fluidized granulating machine; the fluidized granulating system drops into granular material in the closed container; because the effect of hot-air flow; make granular material be fluidized state at the container inner suspension; spray into adhesive and atomizing simultaneously; make powder agglomerate into granule, finish granulation process.This equipment mostly is a batch production, does not satisfy the requirement that streamline is produced, and its product particle out-of-shape, and the fluidized granulating system utilizes the hot-air drying simultaneously, and is same powerless to the material of the easy oxidation of thermal sensitivity.
The utility model content
But the purpose of this utility model is to provide a kind of low temperature granulation, the microencapsulation granulating system that streamline is produced.
The technical scheme that realizes the utility model purpose is: the utlity model has granulation tower, slip service, dry fluid bed and finished product bin; The granulation tower inner and upper is provided with prilling head, and the slip service is connected with prilling head, and the granulation tower bottom connects dry fluid bed by pipeline, and dry fluid bed bottom connects finished product bin by pipeline; Described microcapsule granulating system also is provided with bag by the auxiliary material storehouse, and bag is connected with granulation tower top by pipeline by bottom, auxiliary material storehouse, and bag is connected with dry fluid bed top by pipeline by top, auxiliary material storehouse; Bag is connected with bull ladle by the feed mechanism of auxiliary material by the pipeline between bottom, auxiliary material storehouse and the granulation tower top.
The feed mechanism of above-mentioned microcapsule granulating system comprise be arranged on bag by the auger conveyor of auxiliary material storehouse bottom, be arranged on the auger conveyor exit and be arranged on granulation tower top bag and sent device by the wind of auxiliary material porch.
The wind of the feed mechanism of above-mentioned microcapsule granulating system send device to form by air blast and air cleaner serial connection separately, also is provided with heat exchanger before the air blast.
The granulation tower top bag of above-mentioned microcapsule granulating system is equipped with the dedusting air exhausting device by auxiliary material porch and bag on the pipeline at top, auxiliary material storehouse.
Each dedusting air exhausting device of above-mentioned microcapsule granulating system is in series by cyclone separator, sack cleaner and exhaust blower.
The prilling head of the granulation tower inner and upper of above-mentioned microcapsule granulating system has fixed disk, feed pipe and centrifugal pan, and many circular ports distribute on the centrifugal pan sidewall circumference; Described centrifugal pan directly is connected with the output shaft of drive motors, is provided with the distribution plate that distributes slip between centrifugal pan and the feed pipe, and distribution plate top is connected with feed pipe, and the distribution plate bottom is corresponding with centrifugal pan, and the distribution plate bottom is provided with dispensing orifice.
The distribution plate bottom dispensing orifice of above-mentioned microcapsule granulating system evenly distributes, and each dispensing orifice is oval shape.
The centrifugal pan sidewall circumferential distribution pore of above-mentioned microcapsule granulating system is circular port, and its aperture is all between 0.2～8 millimeter of φ.
The utlity model has following characteristics:
(1) the utility model utilization bag is carried out the microencapsulation granulation to slurry liquid or auxiliary material is arranged as the direct granulation of granulation crystal seed, drying by auxiliary material; can on demand bag be heated to uniform temperature by auxiliary material for different material and carry out granulation; to the material of the easy oxidation of thermal sensitivity, then can realize the low temperature microcapsule granulating.
(2) the utlity model has feed mechanism and dedusting air exhausting device, feeding is unobstructed, and can effectively control dust, and is reasonable in design.
(3) be provided with heat exchanger in the utility model feed mechanism, can regulate the temperature of moving air in the pipeline as required, can reasonably control drying.
(4) prilling head of the present utility model adopts centrifugal pan directly to be connected with the output shaft of drive motors, makes that whole prilling head is simple in structure, and is in light weight, easy to maintenance.
(5) prilling head of the present utility model has distribution plate, and the slip that enters centrifugal pan is evenly distributed, and granulation is effective.
(6) dispensing orifice of the distribution plate of the utility model prilling head bottom is oval shape, is difficult for being stopped up by slip.
(7) the centrifugal pan sidewall circumference of the utility model prilling head has many circular ports, and product particle becomes spherical shape, good fluidity.
Description of drawings
For the easier quilt of content of the present utility model is clearly understood, below the specific embodiment and in conjunction with the accompanying drawings of basis, the utility model is described in further detail, wherein
Fig. 1 is a schematic diagram of the present utility model
Fig. 2 is the structural representation of the utility model prilling head.
Fig. 3 is an A place enlarged diagram among Fig. 2.
The specific embodiment
(embodiment one)
See Fig. 1, the utlity model has granulation tower 1, slip service 2, dry fluid bed 3 and finished product bin 4; Granulation tower 1 inner and upper is provided with prilling head 11, and slip service 2 is connected with prilling head 11, and granulation tower 1 bottom connects dry fluid bed 3 by pipeline, and dry fluid bed 3 bottoms connect finished product bin 4 by pipeline; Microcapsule granulating system also is provided with bag by auxiliary material storehouse 5, and bag can be adopted starch or other corresponding auxiliary materials by auxiliary material; Bag is connected with granulation tower 1 top by pipeline by 5 bottoms, auxiliary material storehouse, and bag is connected with granulation tower 1 bottom and dry fluid bed 3 tops respectively by pipeline by 5 tops, auxiliary material storehouse; Bag is connected with bull ladle by the feed mechanism 6 of auxiliary material by the pipeline between 5 bottoms, auxiliary material storehouse and granulation tower 1 top; Feed mechanism 6 comprise be arranged on bag by the auger conveyor 61 of 5 bottoms, auxiliary material storehouse, be arranged on auger conveyor 61 exits and be arranged on granulation tower 1 top bag and sent device 62 by the wind of auxiliary material porch, wind send device 62 to form by air blast 62a and air cleaner 62b serial connection separately, also is provided with heat exchanger 62c before the air blast 62a; The wind of feed mechanism 6 send between the device 62, bag is equipped with dedusting air exhausting device 7 on the pipeline between 5 tops, auxiliary material storehouse and dry fluid bed 3 tops, and dedusting air exhausting device 7 is in series by cyclone separator 71, sack cleaner 72 and exhaust blower 73.
See Fig. 2 and Fig. 3, the prilling head 11 of microcapsule granulating system granulation tower 1 inner and upper has fixed disk 111, feed pipe 112 and centrifugal pan 113, and centrifugal pan 113 sidewall circumference have many circles and throw away hole 113-1, and its diameter of bore is all between 0.2～8mm; Centrifugal pan 113 directly is connected with the output shaft 115-1 of drive motors 115, be provided with the distribution plate 114 that distributes slip between centrifugal pan 113 and the feed pipe 112, distribution plate 114 tops are connected with feed pipe 112, distribution plate 114 bottoms are corresponding with centrifugal pan 113, the distribution plate 114 bottoms oval shape dispensing orifice 114-1 that evenly distributes.
The bag that is adopted in the present embodiment is a starch by auxiliary material, during system works, starch is sent in the pipeline by auger conveyor 61 by 5 bottoms, auxiliary material storehouse by bag, because wind send the effect of device 62 and dedusting air exhausting device 7, make ducted air produce and flow, thereby the starch that will enter pipeline is sent in the granulation tower 1; After slip is delivered to prilling head 11 in the granulation tower 1 by pump by slip service 2; centrifugal pan 113 by prilling head 11 is thrown out of the numerous spherical liquid pearl of formation; spherical liquid integument starch parcel; starch is rapidly with the moisture sucking-off of liquid bead surface; the liquid pearl rear surface of drying out forms the membranaceous duricrust of protection; effective part is wrapped in inner back form micro-capsule; particle behind the formation micro-capsule and most starch are fallen into by granulation tower 1 and carry out the drying second time in the dry fluid bed 3; in drying; microcapsule granule is separated with starch; starch after the separation is extracted out by wind and is fallen into bag by auxiliary material storehouse 5 after cyclone separator 71 by dedusting air exhausting device 7 separates; starch enters next cyclic program again, and is recycling.Microcapsule granule moisture content is extracted out by vacuum system 8 after reaching requirement, enters finished product bin 4, or by the automatic blanking device finished product is discharged (form of dry fluid bed is circle or rectangle) from dry fluid bed 3, and granulation work can continuous operations.Can send the heat exchanger 62c of device 62 that ducted moving air is heated to predetermined temperature by feed mechanism 6 wind on demand for different material, also be heated to uniform temperature by auxiliary material and carry out the microencapsulation granulation thereby will wrap; To the material of the easy oxidation of thermal sensitivity, then can realize normal temperature even low temperature granulation.
Claims (8)
1. a microcapsule granulating system has granulation tower (1), slip service (2), dry fluid bed (3) and finished product bin (4); Granulation tower (1) inner and upper is provided with prilling head (11), and slip service (2) is connected with prilling head (11), and granulation tower (1) bottom connects dry fluid bed (3) by pipeline, and dry fluid bed (3) bottom connects finished product bin (4) by pipeline; It is characterized in that: described microcapsule granulating system also is provided with bag by auxiliary material storehouse (5), and bag is connected with granulation tower (1) top by pipeline by auxiliary material storehouse (5) bottom, and bag is connected with dry fluid bed (3) top by pipeline by top, auxiliary material storehouse (5); Bag is connected with bull ladle by the feed mechanism of auxiliary material (6) by the pipeline between auxiliary material storehouse (5) bottom and granulation tower (1) top.
2. microcapsule granulating system according to claim 1 is characterized in that: described feed mechanism (6) comprise be arranged on bag by the auger conveyor (61) of auxiliary material storehouse (5) bottom, be arranged on auger conveyor (61) exit and be arranged on granulation tower (1) top bag and sent device (62) by the wind of auxiliary material porch.
3. microcapsule granulating system according to claim 2 is characterized in that: the wind of described feed mechanism (6) send device (62) to form the preceding heat exchanger (62c) that also is provided with of air blast (62a) by air blast (62a) and air cleaner (62b) serial connection separately.
4. microcapsule granulating system according to claim 3 is characterized in that: described granulation tower (1) top bag is equipped with dedusting air exhausting device (7) by auxiliary material porch and bag on the pipeline at top, auxiliary material storehouse (5).
5. microcapsule granulating system according to claim 4 is characterized in that: described each dedusting air exhausting device (7) is in series by cyclone separator (71), sack cleaner (72) and exhaust blower (73).
6. microcapsule granulating system according to claim 1, it is characterized in that: the prilling head (11) of described granulation tower (1) inner and upper has fixed disk (111), feed pipe (112) and centrifugal pan (113), and many circular ports (113-1) distribute on centrifugal pan (113) the sidewall circumference; Described centrifugal pan (113) directly is connected with the output shaft (115-1) of drive motors (115), be provided with the distribution plate (114) that distributes slip between centrifugal pan (113) and the feed pipe (112), distribution plate (114) top is connected with feed pipe (112), distribution plate (114) bottom is corresponding with centrifugal pan (113), and distribution plate (114) bottom is provided with dispensing orifice (114-1).
7. microcapsule granulating system according to claim 6 is characterized in that: described distribution plate (114) bottom dispensing orifice (114-1) evenly distributes, and each dispensing orifice (114-1) is oval shape.
8. microcapsule granulating system according to claim 6 is characterized in that: described centrifugal pan (113) sidewall circumferential distribution pore (113-1) is circular port, and its aperture is all between 0.2～8 millimeter of φ.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007200458551U CN201086012Y (en) | 2007-09-17 | 2007-09-17 | Microcapsule granulation system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007200458551U CN201086012Y (en) | 2007-09-17 | 2007-09-17 | Microcapsule granulation system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201086012Y true CN201086012Y (en) | 2008-07-16 |
Family
ID=39633601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNU2007200458551U Expired - Lifetime CN201086012Y (en) | 2007-09-17 | 2007-09-17 | Microcapsule granulation system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201086012Y (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101391200B (en) * | 2007-09-17 | 2011-11-23 | 陈红斌 | Microcapsule granulation device |
| CN101822963B (en) * | 2009-03-03 | 2012-03-07 | 陈红斌 | Dual fluidized microcapsule granulating system |
-
2007
- 2007-09-17 CN CNU2007200458551U patent/CN201086012Y/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101391200B (en) * | 2007-09-17 | 2011-11-23 | 陈红斌 | Microcapsule granulation device |
| CN101822963B (en) * | 2009-03-03 | 2012-03-07 | 陈红斌 | Dual fluidized microcapsule granulating system |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102274703A (en) | Large-scale continuous energy-saving fluidized bed spraying, granulating and drying process | |
| CN107115315A (en) | Formula and preparation method for the rumen-protected nicotinic acid that prevents ketosis of dairy cows | |
| US20160227816A1 (en) | Process for the production of granules having greatly improved properties from amino acid solutions and suspensions | |
| CN101822963B (en) | Dual fluidized microcapsule granulating system | |
| HU196717B (en) | Apparatus and method for fluidization contacting materials | |
| CN102091566A (en) | One-step granulating and drying equipment with fluidized bed | |
| CN104306353A (en) | Preparation process and device of vitamin D3 microcapsule powder | |
| CN201086012Y (en) | Microcapsule granulation system | |
| CN204952303U (en) | A spray -drying device for starch sugar production | |
| CN101391200B (en) | Microcapsule granulation device | |
| CN101684051A (en) | Production process of organic-inorganic compound fertilizer | |
| CN203342748U (en) | Granulating and drying device of vertical continuous fluidized bed | |
| CN201445649U (en) | Double-fluidization micro-capsule prilling system | |
| KR100848014B1 (en) | Granule manufacturing system of riquid | |
| CN103344093A (en) | Vertical type continuous fluidized bed pelleting drying device and method | |
| CN104431690A (en) | Lycopene microcapsule granules and preparation process thereof | |
| CN1845783B (en) | Method for production of enzyme granules and enzyme granules produced thus | |
| CN101341940B (en) | Method of preparing pellet feed for weaning pigling | |
| CN101366461A (en) | Preparation method for salinomycin sodium fine granular formulation | |
| CN105664790B (en) | A kind of tea polyphenols fluidized bed granulation method | |
| CN201940207U (en) | Granulating and drying device of one-step fluidized bed | |
| CN107468655A (en) | A kind of lentinan particle and preparation method thereof | |
| CN108101639A (en) | Prepare the method and system of charcoal base manure | |
| CN203728738U (en) | Rotary drum pelletizer | |
| CN209901230U (en) | Microbead granulation system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20080716 Effective date of abandoning: 20070917 |