CN201067411Y - Saliva collecting device - Google Patents

Saliva collecting device Download PDF

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Publication number
CN201067411Y
CN201067411Y CNU2007201091018U CN200720109101U CN201067411Y CN 201067411 Y CN201067411 Y CN 201067411Y CN U2007201091018 U CNU2007201091018 U CN U2007201091018U CN 200720109101 U CN200720109101 U CN 200720109101U CN 201067411 Y CN201067411 Y CN 201067411Y
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China
Prior art keywords
sample
saliva
sample collection
indicating area
collection zone
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Expired - Lifetime
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CNU2007201091018U
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Chinese (zh)
Inventor
戴节林
勾利剑
胡海鹏
伍欣
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ABON Biopharm Hangzhou Co Ltd
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ABON Biopharm Hangzhou Co Ltd
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Priority to CNU2007201091018U priority Critical patent/CN201067411Y/en
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Abstract

The utility model relates to the field of saliva sample collecting device applied to collecting saliva and indicating sufficient saliva sample. The saliva sample collecting device comprises a sample collecting area and an indication area connected with the sample collecting area. The sample collecting area is made from water absorbing material with chemical adsorption performance, and the indication area is made from water absorbing material with wicking action function. The utility model has the advantages that: the device comprising the sample collecting area and the indication area with different materials can effectively prevent the salvia sample from backflow, in addition, the arrangement of the indication area can indicate sufficient collected saliva samples.

Description

The saliva collection device
Affiliated field
This utility model relates to saliva sample gathering-device field, is used for collecting and indication saliva sample capacity whether.
Related background art
Common liquid sample is collected, especially saliva collection device, patent US 6 such as Varian company, 489, the sample collection device that proposes among 172 B1, comprise that one is collected head and collects handle, will collect the mouth that head is put into the testee, obtain and put into checkout gear again behind the sample and carry out every detection.This gathering-device, can collect sample simply fast, but there is certain defective: because in collection process, owing to absorb the position deliquescing gradually of saliva, when being subjected to the external force extruding, be easy to generate saliva backflow, particularly when in gathering-device, being placed with some chemical indicators, pollute saliva sample to be detected because of the backflow of liquid.
Some gathering-device, for example US 7,114, and the fluid collection device of describing among 403 B2 can be used for collecting and storage even detection sample.The collection unit branch comprises a handle and a collection head, collects head and adopts sponge or other any materials that can absorb water.Put into measured's mouth with collecting head, certain hour takes out later on, puts into the sample storage parts of this device, by extruding sample solution is transferred to the reservoir part from collecting head.
Also have a kind of saliva sample to collect and checkout gear, such as US 6,998, propose among 273 B1, one is collected and be detected on to this device collection, in order to prevent that effectively sample is back to collecting zone in testing process, health to testing result and tester impacts, this device is provided with movably " fence " device between collecting zone and surveyed area, be equivalent to a switch, can be controlled to collect and make sample and surveyed area reach circulation status again after finishing, carry out next step detection.
At present, when collecting saliva sample, exist the phenomenon that sample solution may reflux, bring difficulty for the collection sample, psychologically cause certain infringement also for the tester, the detection reaction after also may influencing.The generation of backflow phenomenon is that especially the external world exerts pressure, such as chewing because liquid under the free flow state, just is easy to promptly reflux or the adverse current phenomenon making the liquid that reaches poised state originally in one direction or produce backward flowing.In order to overcome the backflow defective that prior art exists, this utility model provides a kind of gathering-device, the sample collection zone of gathering-device and indicating area material are formed upward different, because liquid can not unobstructedly mutually must flow between different materials, can effectively improve backflow phenomenon.
Collect saliva sample in addition, also exist the problem of content of the sample of uncertain collection.Be applied to the saliva sample that drugs detect, particularly serious on this problem, reason has two: at first be that saliva sample is abundant unlike the urine blood sample, the mouth of junkie is often very dried, when collecting saliva, often need produce saliva by the saliva stimulating gland; Next is that junkie often has resisting psychology, and be unwilling to be detected is consume illegal drugs, so may exist sample size to cause detecting failure inadequately when detecting.
Summary of the invention
There is the whether shortcoming of capacity of backflow phenomenon and uncertain sample in order to overcome existing saliva collection device, this utility model provides a kind of safer gathering-device of saliva sample easily, make collection easy more relieved, the result is more apparent in collection, and testing result is more accurate.
The technical scheme that its technical problem that solves this utility model adopts is: this saliva sample gathering-device, comprise sample collection zone and the indicating area that is connected with the sample collection zone, and different materials is adopted in sample collection zone and indicating area.In a preferred scheme, mainly by forming by the absorbent material of chemisorption absorption and storage saliva sample, the indicating area is mainly by forming by the absorbent material of capillarity adsorptive liquid in the sample collection zone.The material that constitutes the sample collection zone can be selected from polyvinyl alcohol (PVA), foam plastics, and resin, the sodium polyacrylate cross-linking agent, the acrylic acid-ethylene acid copolymer, acrylonitrile polymerization is saponified, the combination of one or several of vinyl alcohol or sponge; The material of indicating area is selected from filter paper, glass, the combination of one or several of non-woven fabrics or acetate fiber.Scheme that is more preferably be exactly the material that constitutes the sample collection zone be polyethylene foamed alcohol.
The main principle by chemisorbed in sample collection zone absorbs saliva sample, and the effect by storeroom hydrogen bond and Van der Waals force combines liquid and hydrophilic substance.Constituting the material in sample collection zone, is hydrophilic, the reasonable material of water absorption and water-retaining property, and liquid is extruded out again easily simultaneously.Such as some super-strong moisture absorbing macromolecular materials etc., also claim super absorbent resin, super strength water absorbent or high water absorbency polymer, comprise polyvinyl alcohol (PVA), resin, sodium polyacrylate cross-linking agent, the acrylic acid-ethylene acid copolymer, acrylonitrile polymerization is saponified, and vinyl alcohol all is the new functional macromolecule material with excellent water absorbing capacity and water holding capacity.These materials are in water absorption course, at first by few capillary absorption and peptizaiton suction, pass through the effect of Van der Waals force between hydrogen bond and hydrophilic group then, the hydrophilic group disassociation, electrostatic repulsion forces between the ion makes the network expansion of hydrophilic group, the inside and outside osmotic pressure that produces of network, moisture further infiltrates.Along with the increase of water absorption, the inside and outside osmotic pressure of network trends towards zero, and the expansion of hydrophilic group network the time, its elastic contractile force is also increasing, and offsets anionic Coulomb repulsion gradually, finally reaches the suction balance.The macromolecular material of polyvinyl alcohol especially wherein, though water absorbent rate is not high, absorption speed is than very fast, half of the water absorption that can reach capacity in 2-3 minute.Constituting the material in sample collection zone, can also be sponge, agarose, starch based natural polymer product of chitin and so on or cellulose family natural polymer product or polysaccharide natural polymer product or protein-based natural polymer producing region etc.The suction zone that this material constitutes not only can be drawn a large amount of liquid easily, and simultaneously when being subjected to the external force extruding, liquid is easy to be extruded out and detects chemical examination.
The indicating area is mainly by the capillarity adsorptive liquid.Can produce the material of capillarity, be made up of tubule and slit, tubule and slit are more little, and capillarity is obvious more.It is different that indicating area and above-mentioned sample collection zone absorb the principle of liquid, and the indicating area mainly arrives the state of suction by capillary absorption.The physical essence of the driving force of capillarity is the surface tension of liquid.Principle from surface thermodynamics, when liquid contacts with solid phase surface, liquid will be sprawled on the surface of solids, solid-air interface (the exsiccant indicating area and the external world) is originally replaced by solid-liquid (liquid in exsiccant indicating area and the sample collection zone) and liquid-gas (liquid in the sample collection zone and the external world) interface, liquid can monolayer be dispersed on the surface of solids under the limiting case, reach the state of solid phase times moistening, its basic reason is that solid-air interface tension force is greater than the tensile cause of solid-liquid interface. the material of indicating area can have filter paper, glass, the material that acetate fiber or non-woven fabrics etc. have capillarity constitutes, the intermolecular distance of these materials itself is very little, intramolecular distance is also very little, and material compacts.Because capillary existence when reaching capacity state in the sample collection zone, when liquid contacts with the indicating area, is flowed to the indicating area owing to capillarity drives liquid, reaches the purpose of moistening indicating area.
When the zone of collecting sample is squeezed out saliva, because after the saliva of collecting zone storage is flowed out, remaining space can also be drawn unnecessary sample, because the material of prior art formation indicating area is the same with the material of collecting zone, the saliva that is present in the indicating area like this will be back to collecting zone, and the reagent on the indicating area will pollute sample and makes testing result inaccurate like this.Utilize the technical solution of the utility model, because the indicating area mainly is made of the material that relies on the capillarity adsorptive liquid, the liquid that is attracted on the indicating area almost can not be collected the zone absorption, does not therefore produce backflow phenomenon.
The sample collection zone is different with the material that adopt the indicating area, the material that in this utility model, not only comprises two kinds of unlike materials, but the different material that also comprises the pore size between the material material of the same race, such as being similarly filter paper, the sample collection zone is adopted bibulous, the material that hole is big, and the less material of hole is adopted in the indicating area, when liquid is full of two kinds of materials that are in the liquid communication state, because the difference of pore size, the ability of being detained liquid is also different, and liquid that can not is mobile mutually with being intended between two kinds of materials, can reach the effect that liquid does not reflux like this.Bibulous material can be adopted in the sample collection zone, can effectively must be detained sample, and adopts fairly simple method, such as the extruding etc., just sample can be shifted out from collecting zone, be used for the detection.
The material in sample collection zone can be a polyvinyl alcohol, also can be foam plastics, can also be cotton fiber, sponge, can also be that EVA resin etc. has absorptive material.。
In another embodiment, saliva sample gathering-device indicating area includes and can indicate the whether indicator of capacity of sample by Show Color.The mode of Show Color has multiple, can as being the bonded method of dyestuff, also can arrive the indication purpose by chemical reaction by the mode of physics, such as the reaction that utilizes potassium thiocyanate and ferric ion, wine-colored color reaction occurs.Collect if be used for saliva sample, can also be by the amylase substrate be set on the indicating area, the amylase when saliva sample reaches the indicating area in the saliva and its substrate be used for judging whether capacity, play indicative function.
In another embodiment, the material of Show Color comprises food coloring in the saliva sample device.Food coloring can be natural pigment, can be synthetic dyestuff also, comprises gardenia yellow, Fructus Gardeniae orchid, ferrum oxide (deceiving) etc.Natural pigment is safe to use, but because the extraction cost height, so its use cost is higher.And synthetic dyestuff have lovely luster, strong coloring force, stability better, be suitable for toning and composite, the advantage that price is low is so that it is used is comparatively general and extensive.In application of the present utility model, choose food coloring as indicator based on following principle, at first, change color is wanted obviously, such as becoming blueness from white or transparent color, should avoid yellow, color beastly such as redness.Secondly, the indicator stable in properties, change color can be kept the sufficiently long time, can continue in the time of guaranteeing to use to observe to detect to be executed correctly, and should avoid character such as sensitization.The 3rd, the indicator of employing is wanted safety, and human body is not had toxic and side effects.The 4th, the indicator of employing can not exert an influence to the result of pattern detection, does not disturb composition original in the sample.
In another embodiment, described saliva sample receiving apparatus, the indicating area comprises a coloured material, this material to small part is covered by a basic opaque layer, when liquid exists,, described opaque layer clear described coloured material can be observed thereby becoming transparent.Coloured material described here can comprise the parts of being with food coloring, colored absorbent material.When sample arrives the indicating area by collecting zone, the opaque layer that covers on the coloured material is soaked into, user can stop to collect the operation of sample by the change of color, and clear and definite sample collection amount enough has been used for other detection reaction, carries out next step operation.
In another embodiment, described saliva sample receiving apparatus, indicator comprises the PH agent.On the indicating area, be written into the PH agent, such as the PH reagent paper, according to the pH value difference of saliva sample.Among the normal human, the pH value of saliva greatly about about 7, meta-acid slightly after the feed, the pH value of urine is between 5-7, the pH value of blood is about 7.35.When collecting saliva, sample arrives the indicating area by capillarity, be positioned at the PH reagent paper contact sample on the indicating area after, soaked into into grass green by original yellow, change color takes place, reach indicative function.
In another embodiment kind, the saliva sample gathering-device comprises the sample collection zone that is made of polyethylene foamed alcohol, be in the indicating area of liquid communication state with the sample collection zone, this indicating area comprises the indicator that the adsorptive pads that is made of filter paper and food coloring constitute.On food coloring, can cover a skim, food coloring is manifested.This device can also comprise a handle, and handle is provided with the window of observed result, by capillarity, food coloring is driven along the direction of liquid flow and flows, and finally is observed in results area.The window of observed result can be an aperture, also can reach the purpose of observed result by adopting transparent material.
In another embodiment, the saliva sample gathering-device comprises the sample collection zone that is made of polyethylene foamed alcohol, be in the indicating area of liquid communication state with the sample collection zone, this indicating area comprises the indicator that the adsorptive pads that is made of filter paper and temperature-sensitive material constitute.Temperature-sensitive material can be the polymer that daiamid composition is formed.Because saliva sample has temperature when just having separated from human body, so at short notice, the variation that temperature sensitive material can sense temperature on the indicating area changes on physicochemical property, reaches the result of indication capacity.
In another embodiment, the indicating area on the saliva sample gathering-device comprises a reagent strip.Reagent strip comprises the sample acceptance region, marked region, and control area and sample store the zone as a result.The sample acceptance region of reagent strip can overlap mutually with the sample collection zone, and saliva can be circulated between the two.Saliva sample reaches the acceptance region by the sample collection zone, because the capillarity saliva sample can continue by drain, arrives the indicating area.Indicator in the indicating area can show that in control area as a result saliva sample arrive the indicating area when running into saliva sample, thus show saliva sample capacity be used for detecting.The indicating area and as a result the control area can be same place, also can be that the control area is positioned at the downstream of indicating area as a result.Movably indicator can be contained in the indicating area that is arranged in upstream position, when sample solution arrives the indicating area, because capillarity drives movably indicator arrival control area as a result, shows the sample capacity.The function that sample stores the zone is that unnecessary saliva sample solution and indicator are trapped in wherein.
The beneficial effect that this utility model is obtained is: 1. the material of collecting zone and surveyed area is different, can effectively must prevent backflow phenomenon, particularly when also having indicator on the indicating area, owing to can not refluxing, liquid pollutes saliva sample 2. on the collecting zone when collecting sample, can whether can reach the requirement of detection according to the amount of the change color extrapolated sample of indicating area, guarantee the accuracy that detects.
Description of drawings
Fig. 1 is a perspective view of the present utility model;
Fig. 2 is an explosive decomposition structural representation of the present utility model;
Fig. 3 is the blast structural representation of this utility model indicating area;
Fig. 4 is the sketch map before this utility model uses;
Fig. 5 is the sketch map after this utility model uses;
Fig. 6 is the planar structure sketch map of another embodiment of this utility model.
Description of drawings labelling: handle 1, window 11, chassis 12, cavity 13, indicating area 2, adsorptive pads one end 21, another end 22 of adsorptive pads, coverlay 23, indicator 24, adsorptive pads 25, sample collection zone 3, sample collection zone one end 31.
The specific embodiment
Below in conjunction with concrete accompanying drawing examples of implementation of the present utility model are described in detail.These specific embodiment only are limited the enumerating under this utility model spirit, do not get rid of one of ordinary skill in the art prior art and this utility model in conjunction with and other specific embodiments of producing.
Embodiment 1: this saliva sample gathering-device, comprise the sample collection zone 3, indicating area 2 and the handle 1 that constitute by polyethylene foamed alcohol, one end 21 of indicating area is connected with sample collection zone 3, and the other end 22 is arranged in the cavity 13 of an end opening of handle.Also comprise a window 11 and a chassis 12 that connects sample collection zone 3 on the handle 1.Indicating area 2 comprises coverlay 23, indicator 24 and adsorptive pads 25.Indicator 24 is made of food coloring.Saliva sample can be absorbed by sample collection zone 3, reaches on the indicator 24 by adsorptive pads 25 then, and sample solution mixes with indicator in the indicating area and to drive the indicator continuation mobile to the other end of adsorptive pads 25, further soaks into coverlay 23.Owing to have window 11 on the handle 1, when color is presented on the window 11, can think that the liquid saliva sample collects capacity, can be used for next step detection.
The sample collection zone
Being connected of sample collection zone 3 and indicating area 2, adopt directly to connect or indirect ways of connecting.Directly connect, be that one terminal 21 of the regional adsorptive pads 25 of indication directly inserts in the sample collection zone, like this, saliva sample reaches a certain amount of in sample collection zone 3 when, just can sample solution be drawn to indicating area 2 by capillarity, thereby play the whether effect of capacity of sample that shows by the end 21 of adsorptive pads.Connect indirectly, can pass through other absorbent materials, sample collection zone 3 is directed on this absorbent material, pass through the interconnect function of this absorbent material and adsorptive pads 25 again, sample is directed to the indicating area by capillarity, briefly, be exactly absorbent material on overlap joint between sample collection zone 3 and the indicating area 2, play the effect of liquid communication.
Sample collection zone 3 is different with the adsorptive pads material of indicating area 2, and it is main material that polyethylene foamed alcohol is adopted in sample collection zone 3, and this material has white and opens hollow structure, matter is hard when doing, suction back quality softness has elasticity, is not subject to Bacteria destroyed, can sterilize, the polyvinyl alcohol molecule has a large amount of hydroxyls, have tangible hydrophilic, in addition, this material water-retaining property is fabulous, liquid is filled also and can ooze, and relatively is fit to the collection of saliva of buccal cavity.In this material, some can also be added and the salivary chemical constituent of people can be impelled, but the material that can not make a difference to pattern detection, such as citric acid etc.Adding this type of material can stimulate detected person's salivary gland, and mouthful more dried tester because take drugs especially is so that the capacity of sample is collected.
In actual mechanical process, polyethylene foamed alcohol material is when contact saliva, and under the effect of hydrogen bond and Van der Waals force, absorbed fluid molecule and polyvinyl alcohol molecule are crosslinked together mutually, are present in the molecule gap of this material.Polyethylene foamed alcohol becomes soft flexible after wetted, have fabulous water retention property.When the saliva in sample collection zone 3 reached capacity state, adsorptive pads 25 1 ends that are positioned at 3 tops, sample collection zone contacted with the saliva sample in sample collection zone, by the form arrival adsorptive pads of molecular diffusion.Adsorptive pads 25 is made of filter paper, and filter paper inside has many tubules, and the spacing between the tubule is also very little, is the essential condition of capillary formation.In the capillary tube of surface tension at filter paper of the liquid on the sample collection zone 3, form a concave meniscus, this concave meniscus presses to following liquid, make liquid rise along tube wall, when the pulling force that makes progress equates with the suffered gravity of fluid column in the capillary tube of filter paper, liquid in the pipe stops to rise, and reaches balance.Capillary tube in the filter paper is numerous, parallel to each other crosslinked, forms a network channel, makes that liquid is constant at short notice must rise, until adsorptive pads is soaked into fully.In said process, because indicator 24 is in a certain position of adsorptive pads 25, in the process along with the rising of capillarity liquid, indicator 24 also contacts with saliva sample, is soaked into, the final indication result that shows.In the time of extruding sample collection zone 3, because the capillary adsorption of filter paper, the liquid that can not that is present on the filter paper is absorbed by the sample collection zone, thereby the chemical indicator that is present on the filter paper can not pollute saliva sample to the sample collection zone with liquid return.
The indicating area
Indicating area 2 comprises adsorptive pads 25, indicator 24 and coverlay 23.
The material of adsorptive pads 25 is a filter paper.Adsorptive pads 25 has good absorbent function and drain function, and sample solution can be easy to such an extent that reach the other end 22 from an end 21 of adsorptive pads by capillarity.Because the existence of adsorptive pads 25 can also produce an extra pull strength to sample collection zone 3, makes flowing toward a direction of saliva sample.One terminal 21 of adsorptive pads directly inserts in the absorbent material on top 31, sample collection zone, and saliva sample can reach adsorptive pads 25 along terminal 31 after being full of sample collection zone 3.Indicator adopts food coloring, considers that mainly food coloring obtains than being easier on raw material, and cheap, is easier to realize at industrial ratio.Indicator 24 can be placed on a certain position of adsorptive pads 25, is placed on the adsorptive pads 25 after also can being soaked by an absorbent material.Be positioned at the food coloring of adsorptive pads 25 a certain positions, can be dissolved when saliva sample is flowed through, penetrate coverlay 23, thereby by the window 11 on the handle 1 as seen.Also can be mobile together, at other position Show Colors of adsorptive pads 25 according to the direction of liquid flow.
Handle
Handle 1 comprises window 11, the cavity 13 of a chassis 12 and an end opening.Window 11 is arranged on the handle 1, and the size shape of window 11 is unrestricted, can observe change color and get final product.The effect on chassis 12 is to connect and fixed sample collecting zone 3, can be provided with hasp on the chassis 12 sample collection device 3 is fixed on an end of handle 1, also can sample collection zone 1 be bonded on the chassis 12 by being stained with sticking form, such as employing glue.The center on chassis 12 is the inlet of handle internal channel 13, and indicating area 2 can be placed in this passage 13, and an end 22 of adsorptive pads also can be connected with sample collection zone 3 by this passage 13.
Embodiment 2: this saliva sample gathering-device, comprise sample collection zone 3, indicating area 2 and transparent handle 1, and an end 21 of indicating area is connected with sample collection zone 3, and the other end 22 is comprised in the cavity 13 of the end opening in the handle.Also comprise a chassis 12 that connects sample collection zone 3 on the handle 1.Indicating area 2 comprises coverlay 23, dyestuff 24 and adsorptive pads 25.Saliva sample can be absorbed by sample collection zone 3, reach on the indicating area 2 by adsorptive pads 25 then, sample solution in the indicating area 2 with the dyestuff dissolving and drive dyestuff and continue to flow to the other end of adsorptive pads 25.Dyestuff 24 be because flowing of saliva sample can be flushed to another closed end of handle cavity 13, can Show Color on transparent handle 1, can think that saliva sample collects capacity, and can be used for next step detection.
Embodiment 3: this saliva sample gathering-device comprises sample collection zone 3, indicating area 2 and handle 1.The indicating area 2 that is in the liquid communication state with sample collection zone 3 comprises adsorptive pads 25 and the PH reagent paper 24 that is made of filter paper.Because the various pH value differences of human body fluid when liquid arrives PH reagent paper 24, can reach indication result's effect because the difference of acid-base value presents different colors.The result that capacity is collected is read by the window on the handle 1 11.
Embodiment 4: this saliva sample gathering-device comprises the indicator that is made of the amylase substrate.The amylase substrate is a certain colourless when drying, the material of Show Color when soaking into, and this material spreads all over whole piece adsorptive pads 25.After being soaked into by saliva, the amylase in the saliva acts on it, blue chromogenic reaction occurs.
The operating process of this utility model when collecting:
1. testee's mouth is put in the sample collection zone of this gathering-device, in the absorbed process of saliva sample,
The tester can feel and is full of the deliquescing gradually of sample collection zone saliva, but can not oozes.
2. the observation indicating area if change color occurs, then illustrates sample collection capacity.
3. the taking-up gathering-device is used for next step stored samples or check and analysis.

Claims (9)

1. a saliva collection device comprises sample collection district and the indicating area that is connected with the sample collection zone, and it is characterized in that: the sample collection zone is made of the absorbent material with chemisorption, and the indicating area constitutes by having capillary absorbent material.
2. saliva collection device as claimed in claim 1, it is characterized in that, the absorbent material of forming the sample collection zone is selected from polyvinyl alcohol, foam plastics, sodium polyacrylate cross-linking agent, the acrylic acid-ethylene acid copolymer, acrylonitrile polymerization is saponified, one of vinyl alcohol, and the absorbent material of forming the indicating area is selected from filter paper, glass, one of non-woven fabrics or acetate fiber.
3. saliva collection device as claimed in claim 1 is characterized in that, the material in sample collection zone is a polyethylene foamed alcohol.
4. saliva collection device as claimed in claim 1 is characterized in that, an end of described indicating area is positioned at the sample collection zone.
5. saliva collection device as claimed in claim 1 is characterized in that, described sample collection zone is made of polyethylene foamed alcohol, and the indicating area that is connected with sample collection zone comprises the indicator that the adsorptive pads that is made of filter paper and food coloring constitute.
6. saliva collection device as claimed in claim 1 is characterized in that, described sample collection zone is made of polyethylene foamed alcohol, and the indicating area that is connected with sample collection zone comprises the indicator that the adsorptive pads that is made of filter paper and PH agent constitute.
7. saliva collection device as claimed in claim 1, it is characterized in that, described sample collection zone is made of polyethylene foamed alcohol, the indicating area that is connected with the sample collection zone comprises a reagent strip, this reagent strip comprises the indicator that the adsorptive pads that is made of filter paper and food coloring constitute, the saliva collection device also comprises the handle with cavity, and this reagent strip is positioned at the cavity of handle.
8. saliva collection device as claimed in claim 7 is characterized in that described handle is transparent.
9. saliva collection device as claimed in claim 7 is characterized in that, includes the window that can observe the indication result on the described handle.
CNU2007201091018U 2007-05-11 2007-05-11 Saliva collecting device Expired - Lifetime CN201067411Y (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108348913A (en) * 2015-10-26 2018-07-31 幸福科技公司 Lateral flow assay device and method
CN108498960A (en) * 2018-04-17 2018-09-07 天津滨海华医光电技术有限公司 A kind of semiconductor laser therapeutic instrument adjustable probe
WO2020048096A1 (en) * 2018-09-09 2020-03-12 王水娟 Liquid acquisition device
CN113768548A (en) * 2020-06-10 2021-12-10 株式会社村田制作所 Oral appliance

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108348913A (en) * 2015-10-26 2018-07-31 幸福科技公司 Lateral flow assay device and method
CN108498960A (en) * 2018-04-17 2018-09-07 天津滨海华医光电技术有限公司 A kind of semiconductor laser therapeutic instrument adjustable probe
WO2020048096A1 (en) * 2018-09-09 2020-03-12 王水娟 Liquid acquisition device
CN113768548A (en) * 2020-06-10 2021-12-10 株式会社村田制作所 Oral appliance

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Granted publication date: 20080604