CN201060194Y - Gene chip - Google Patents
Gene chip Download PDFInfo
- Publication number
- CN201060194Y CN201060194Y CNU2007200716341U CN200720071634U CN201060194Y CN 201060194 Y CN201060194 Y CN 201060194Y CN U2007200716341 U CNU2007200716341 U CN U2007200716341U CN 200720071634 U CN200720071634 U CN 200720071634U CN 201060194 Y CN201060194 Y CN 201060194Y
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- carrier
- diaphragm
- chip
- genetic chip
- gene chip
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Abstract
The utility model provides a convenient and economical combined gene chip, which relates to the technical field of the biochip technology and clinical in vitro diagnostic tests. The utility model is combined by a carrier and a viscous film possessing hollowed reaction zone on the carrier. The utility model is used for conveniently and rapidly executing multi-disease and multi-person parallel diagnoses, can lower the producing technical demand on the gene chip carrier, can lessen the cost investment, and can facilitate the popularization and the application of the multi-index and multi-person parallel testing gene chip.
Description
Technical field
The utility model relates to biochip technology and external clinical diagnosis detection technique field, relates more specifically to a kind of genetic chip that is suitable for many indexs, the parallel detection of many person-portions.
Background technology
Genetic chip is because the demand of high flux, broad scale research gene function produces at first, as the chip product of most popular U.S. Affymetrix company in the market.Increasingly mature along with chip technology it is found that genetic chip has unique application prospect and huge commercial market in communicable disease and genetic disease diagnosis.Relevant research and design is also launched day by day.From considering financial cost, the angle of efficient detection is set out, and the design of many indexs, many person-portions genetic chip is also arranged.Be the multiple person diagnosis gene chip carrier of being mentioned in 00114996 the application as Bodao Gene Development Co., Ltd., Shanghai's application number,, reach the purpose that many indexs and many person-portions detect by a plurality of recessed point sample ponds of design on chip carrier.This design is used easy, but because chip has washing step after use, it is unclean that the design of groove is removed washing lotion, and makes the interpretation as a result of chip produce error; And the processing request to carrier is very high aborning.Because domestic genetic chip company entrusts other unit to make mould, has increased cost so greatly.The chip design that with the slide is carrier is an example, and at the detection requirement of different person-portions, slide need be processed into the reaction zone of varying number, and the cost of each die sinking tool is very high.The more important thing is that genetic chip is very high to the requirement of flatness, and domestic technological level does not often reach requirement, this has also increased production cost.Also there be such using and economic, technologic problem for other carrier.These factors have greatly influenced the popularization research of many indexs, many person-portions parallel detection genetic chip and have utilized.
Summary of the invention
In order to eliminate the influence of washing step to the genetic chip sentence read result, and reduction is to the manufacture craft requirement of gene chip carrier, reduce the cost input, be beneficial to applying of many indexs, many person-portions parallel detection genetic chip, the utility model will provide a kind of convenient economic combined genetic chip, can not only reduce and make chip carrier technological requirement and production cost, not influence convenient and swift that genetic chip detects simultaneously again.
The utility model provides a kind of genetic chip, it is characterized in that: be made up of carrier (1) and the diaphragm (2) that covers superincumbent band reaction vacancy section.
The material of said carrier (1) can be modified glass, plastics, silicon.
The material of said carrier (1) can be the super flat slide of standard microslide specification.
Said diaphragm (2) can be the elastomeric material that one side has viscous coating, plastic material.
The thickness of said diaphragm (2) is between 0.1mm-15mm.
The reaction vacancy section area of said diaphragm (2) is 1mm
2-100mm
2Between rectangle, circle, rhombus.
The reaction vacancy section of said diaphragm (2) can be 1mm-20mm for length, and wide is the rectangle of 1mm-60mm.
Description of drawings
Fig. 1 is rectangular a kind of genetic chip for the reaction vacancy section that covers diaphragm on the super flat microslide.
Fig. 2 is that the reaction vacancy section that covers diaphragm on the plastic carrier is circular a kind of genetic chip
Embodiment
Genetic chip shown in Figure 1, its embodiment is as follows: get the microslide of amino or aldehyde group modified mistake, cover plastics or picture glue film on non-marked area.The wide 25mm of this diaphragm, long 70mm, thick 1mm.The hollow out of top parallel arranged is a reaction zone, can be reaction chamber after sticking on the slide.This reaction zone is that length and width respectively are the square of 8mm.Can point sample combine nucleic acid probe with disease association to be detected with the corresponding ground of reaction zone on the slide.
Genetic chip shown in Figure 2, its embodiment is as follows: get the silicon chip of amino or aldehyde group modified mistake, cover plastics or picture glue film on non-marked area.The wide 80mm of this diaphragm, long 80mm, thick 3mm.The hollow out of top parallel arranged is a reaction zone, can be reaction chamber after sticking on the silicon chip.This reaction zone is that diameter is the circle of 8mm.Can point sample combine nucleic acid probe with disease association to be detected with the corresponding ground of reaction zone on the silicon chip.
Claims (7)
1. genetic chip is characterized in that: be made up of carrier (1) and the diaphragm (2) that covers superincumbent band reaction vacancy section.
2. genetic chip as claimed in claim 1 is characterized in that: the material of said carrier (1) can be modified glass, plastics, silicon.
3. genetic chip as claimed in claim 2 is characterized in that: the material of said carrier (1) can be the super flat slide of standard microslide specification.
4. genetic chip as claimed in claim 1 is characterized in that: said diaphragm (2) can be the elastomeric material that one side has viscous coating, plastic material.
5. genetic chip as claimed in claim 4 is characterized in that: the thickness of said diaphragm (2) is between 0.1mm-15mm.
6. as claim 4 or 5 described genetic chips, it is characterized in that: the reaction vacancy section area of said diaphragm (2) is 1mm
2-100mm
2Between rectangle, circle, rhombus.
7. genetic chip as claimed in claim 6 is characterized in that: the reaction vacancy section of said diaphragm (2) can be 1mm-20mm for length, and wide is the rectangle of 1mm-60mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007200716341U CN201060194Y (en) | 2007-06-26 | 2007-06-26 | Gene chip |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007200716341U CN201060194Y (en) | 2007-06-26 | 2007-06-26 | Gene chip |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201060194Y true CN201060194Y (en) | 2008-05-14 |
Family
ID=39408675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNU2007200716341U Expired - Lifetime CN201060194Y (en) | 2007-06-26 | 2007-06-26 | Gene chip |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201060194Y (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102539740A (en) * | 2010-12-29 | 2012-07-04 | 河北省健海生物芯片技术有限责任公司 | Protein chip and method for detecting 80 kinds of autoantibodies simultaneously |
| US11391749B2 (en) | 2018-11-08 | 2022-07-19 | Boe Technology Group Co., Ltd. | Gene chip and gene detection device |
-
2007
- 2007-06-26 CN CNU2007200716341U patent/CN201060194Y/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102539740A (en) * | 2010-12-29 | 2012-07-04 | 河北省健海生物芯片技术有限责任公司 | Protein chip and method for detecting 80 kinds of autoantibodies simultaneously |
| US11391749B2 (en) | 2018-11-08 | 2022-07-19 | Boe Technology Group Co., Ltd. | Gene chip and gene detection device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Shanghai Yulong limited medical examination Assignor: Shanghai Yulong Biological Science And Technology Co., Ltd. Contract record no.: 2011310000223 Denomination of utility model: Washing method for fluorescent label of gene chip and its special elution liquid Granted publication date: 20080514 License type: Exclusive License Record date: 20111021 |
|
| CX01 | Expiry of patent term |
Granted publication date: 20080514 |
|
| CX01 | Expiry of patent term |